Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4h8w_G.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TRP 2.A NE1 GLU 48.A OE2 no hydrogen 2.881 N/A LYS 3.A N GLN 335.A O no hydrogen 3.029 N/A LEU 9.A N GLN 60.A OE1 no hydrogen 2.836 N/A PHE 10.A N CYS 102.A O no hydrogen 3.058 N/A CYS 11.A SG ALA 30.A O no hydrogen 3.473 N/A ALA 12.A N HIS 100.A O no hydrogen 2.824 N/A SER 13.A N VAL 32.A O no hydrogen 2.989 N/A ALA 15.A N SER 13.A OG no hydrogen 2.989 N/A LYS 16.A N ASN 24.A OD1 no hydrogen 2.897 N/A LYS 16.A NZ ASP 14.A O no hydrogen 2.903 N/A GLU 19.A N LYS 16.A O no hydrogen 3.233 N/A GLU 21.A N GLU 19.A OE1 no hydrogen 3.066 N/A VAL 22.A N SER 93.A O no hydrogen 2.885 N/A HIS 23.A N GLU 21.A OE2 no hydrogen 3.039 N/A HIS 23.A ND1 GLU 21.A OE2 no hydrogen 2.743 N/A ASN 24.A N GLU 21.A OE1 no hydrogen 2.844 N/A ASN 24.A ND2 GLU 21.A OE1 no hydrogen 2.796 N/A VAL 25.A N GLU 21.A O no hydrogen 3.010 N/A TRP 26.A N VAL 22.A O no hydrogen 2.913 N/A ALA 27.A N HIS 23.A O no hydrogen 2.848 N/A THR 28.A N ASN 24.A O no hydrogen 2.890 N/A THR 28.A OG1.A ASN 24.A O no hydrogen 3.146 N/A THR 28.A OG1.A VAL 25.A O no hydrogen 3.135 N/A HIS 29.A N TRP 26.A O no hydrogen 3.076 N/A ALA 30.A N TRP 26.A O no hydrogen 2.700 N/A CYS 31.A N ALA 27.A O no hydrogen 2.944 N/A VAL 32.A N CYS 11.A O no hydrogen 2.981 N/A THR 34.A N SER 13.A O no hydrogen 3.217 N/A THR 34.A OG1.A ASP 14.A OD1 no hydrogen 3.431 N/A THR 34.A OG1.B ASP 14.A OD1 no hydrogen 2.558 N/A ILE 41.A N SER 128.A O no hydrogen 3.043 N/A LEU 43.A N VAL 126.A O no hydrogen 2.937 N/A VAL 46.A N LEU 43.A O no hydrogen 3.230 N/A GLU 48.A N CYS 123.A O no hydrogen 3.146 N/A ASN 49.A N GLU 48.A OE1 no hydrogen 2.810 N/A PHE 50.A N GLY 121.A O no hydrogen 2.857 N/A MET 52.A N GLY 119.A O no hydrogen 2.806 N/A TRP 53.A N ASN 51.A OD1 no hydrogen 3.042 N/A LYS 54.A N ASN 51.A O no hydrogen 3.116 N/A MET 57.A N ASN 55.A OD1 no hydrogen 3.128 N/A VAL 58.A N ASN 55.A O no hydrogen 2.891 N/A GLU 59.A N GLU 59.A OE2 no hydrogen 3.012 N/A GLN 60.A N ASN 56.A O no hydrogen 3.066 N/A GLN 60.A NE2 THR 7.A O no hydrogen 2.811 N/A GLN 60.A NE2 ASN 56.A OD1 no hydrogen 2.864 N/A MET 61.A N MET 57.A O no hydrogen 3.010 N/A GLN 62.A N VAL 58.A O no hydrogen 2.941 N/A GLU 63.A N GLU 59.A O no hydrogen 3.036 N/A ASP 64.A N GLN 60.A O no hydrogen 3.078 N/A VAL 65.A N MET 61.A O no hydrogen 2.822 N/A ILE 66.A N GLN 62.A O no hydrogen 3.045 N/A SER 67.A N.A GLU 63.A O no hydrogen 3.017 N/A SER 67.A N.B GLU 63.A O no hydrogen 3.046 N/A SER 67.A OG.B GLU 63.A O no hydrogen 3.167 N/A LEU 68.A N ASP 64.A O no hydrogen 2.809 N/A TRP 69.A N VAL 65.A O no hydrogen 2.832 N/A ASP 70.A N ILE 66.A O no hydrogen 2.740 N/A GLN 71.A N SER 67.A O.A no hydrogen 2.997 N/A GLN 71.A N SER 67.A O.B no hydrogen 2.972 N/A SER 72.A N LEU 68.A O no hydrogen 2.983 N/A SER 72.A N TRP 69.A O no hydrogen 3.266 N/A SER 72.A OG LEU 68.A O no hydrogen 2.788 N/A LEU 73.A N TRP 69.A O no hydrogen 3.085 N/A GLN 74.A NE2 SER 72.A O no hydrogen 3.467 N/A CYS 76.A N MET 282.A O no hydrogen 2.671 N/A VAL 77.A N MET 282.A O no hydrogen 3.193 N/A LYS 78.A N ILE 85.A O no hydrogen 2.902 N/A LEU 79.A N GLN 280.A O no hydrogen 2.805 N/A THR 80.A N SER 83.A O no hydrogen 3.010 N/A SER 83.A N THR 80.A O no hydrogen 2.815 N/A ILE 85.A N LYS 78.A O no hydrogen 2.925 N/A GLN 87.A N CYS 76.A O no hydrogen 3.001 N/A GLN 87.A NE2 PRO 75.A O no hydrogen 2.822 N/A LYS 91.A NZ GLU 242.A OE1 no hydrogen 3.361 N/A LYS 91.A NZ GLU 242.A OE2 no hydrogen 2.825 N/A LYS 91.A NZ ALA 284.A O no hydrogen 3.451 N/A LYS 91.A NZ PRO 285.A O no hydrogen 2.892 N/A ASP 95.A N GLU 21.A OE2 no hydrogen 2.759 N/A ILE 99.A N ILE 135.A O no hydrogen 2.857 N/A HIS 100.A N ALA 12.A O no hydrogen 2.908 N/A HIS 100.A ND1 THR 132.A O no hydrogen 2.780 N/A TYR 101.A N THR 132.A OG1 no hydrogen 2.857 N/A TYR 101.A OH ASP 64.A OD2 no hydrogen 2.714 N/A CYS 102.A N PHE 10.A O no hydrogen 2.792 N/A THR 103.A N GLN 130.A O no hydrogen 3.330 N/A THR 103.A OG1 GLN 130.A O no hydrogen 3.553 N/A TYR 107.A N PRO 104.A O no hydrogen 3.312 N/A VAL 108.A N VAL 334.A O no hydrogen 2.955 N/A ILE 109.A N VAL 129.A O no hydrogen 3.286 N/A LEU 110.A N LYS 332.A O no hydrogen 2.781 N/A LYS 111.A N SER 127.A O no hydrogen 2.859 N/A CYS 112.A N LYS 330.A O no hydrogen 2.853 N/A ASN 113.A N ASN 125.A O no hydrogen 2.737 N/A ASN 113.A ND2 ASN 125.A O no hydrogen 3.210 N/A ASN 113.A ND2 ASN 125.A OD1 no hydrogen 3.672 N/A ASN 113.A ND2 SER 127.A OG no hydrogen 2.955 N/A LYS 115.A NZ GLU 151.A OE1 no hydrogen 2.924 N/A ASN 116.A ND2 GLU 152.A OE1 no hydrogen 2.876 N/A PHE 117.A N ASP 114.A O no hydrogen 3.280 N/A THR 120.A N ASN 118.A OD1 no hydrogen 2.959 N/A THR 120.A OG1 ASN 118.A OD1 no hydrogen 3.452 N/A GLY 121.A N PHE 50.A O no hydrogen 2.914 N/A CYS 123.A N GLU 48.A O no hydrogen 2.765 N/A CYS 123.A SG ASN 125.A O no hydrogen 3.600 N/A LYS 124.A N ASP 114.A OD2 no hydrogen 2.750 N/A LYS 124.A NZ THR 47.A OG1 no hydrogen 2.869 N/A SER 127.A N LYS 111.A O no hydrogen 2.936 N/A SER 127.A OG GLU 40.A OE2 no hydrogen 2.783 N/A SER 128.A N ILE 41.A O no hydrogen 2.840 N/A VAL 129.A N ILE 109.A O no hydrogen 2.806 N/A THR 132.A N TYR 101.A O no hydrogen 2.852 N/A THR 132.A OG1 HIS 133.A O no hydrogen 2.867 N/A HIS 133.A N TYR 331.A OH no hydrogen 3.008 N/A HIS 133.A ND1 TYR 331.A OH no hydrogen 2.612 N/A HIS 133.A NE2 GLU 327.A OE1 no hydrogen 2.960 N/A ILE 135.A N ILE 99.A O no hydrogen 2.724 N/A VAL 138.A N LYS 136.A O no hydrogen 2.898 N/A SER 140.A OG LEU 143.A O no hydrogen 2.694 N/A THR 141.A N SER 236.A O no hydrogen 3.088 N/A THR 141.A OG1 GLU 231.A O no hydrogen 2.800 N/A THR 141.A OG1 MET 234.A O no hydrogen 2.890 N/A THR 141.A OG1 SER 236.A OG no hydrogen 3.348 N/A GLN 142.A N GLY 316.A O no hydrogen 2.833 N/A GLN 142.A NE2 ILE 232.A O no hydrogen 3.087 N/A LEU 143.A N THR 141.A O no hydrogen 2.801 N/A LEU 144.A N GLY 299.A O no hydrogen 2.906 N/A ASN 146.A N ASN 296.A O no hydrogen 2.789 N/A GLY 147.A N THR 298.A OG1 no hydrogen 3.066 N/A SER 148.A N GLU 327.A OE2 no hydrogen 2.728 N/A SER 148.A OG GLU 327.A OE1 no hydrogen 2.624 N/A SER 148.A OG GLU 327.A OE2 no hydrogen 3.193 N/A ALA 150.A N LEU 172.A O no hydrogen 2.885 N/A GLU 153.A N ASN 116.A OD1 no hydrogen 3.132 N/A ILE 155.A N HIS 171.A O no hydrogen 3.050 N/A ARG 157.A N ILE 169.A O no hydrogen 2.764 N/A ARG 157.A NH1 PHE 117.A O no hydrogen 2.840 N/A ARG 157.A NH2 HIS 171.A ND1 no hydrogen 3.001 N/A ASN 160.A N SER 158.A OG no hydrogen 2.863 N/A THR 162.A OG1 ASN 160.A OD1 no hydrogen 2.737 N/A ASN 163.A N ASN 160.A O no hydrogen 2.997 N/A ASN 164.A ND2 ASP 305.A O no hydrogen 2.923 N/A ALA 165.A N ASN 163.A OD1 no hydrogen 2.923 N/A LYS 166.A N ASN 163.A O no hydrogen 3.022 N/A LYS 166.A NZ GLU 159.A OE1 no hydrogen 2.895 N/A THR 167.A OG1 ASP 322.A OD2 no hydrogen 3.556 N/A ILE 168.A N LEU 302.A O no hydrogen 2.796 N/A ILE 169.A N ARG 157.A O no hydrogen 2.781 N/A VAL 170.A N ILE 300.A O no hydrogen 2.865 N/A HIS 171.A N ILE 155.A O no hydrogen 2.865 N/A HIS 171.A NE2 SER 148.A O no hydrogen 2.769 N/A LEU 172.A N THR 298.A O no hydrogen 3.046 N/A ASN 173.A ND2 GLU 152.A O no hydrogen 2.770 N/A VAL 176.A N ILE 297.A O no hydrogen 3.232 N/A ILE 178.A N SER 295.A O no hydrogen 2.836 N/A ASN 179.A N GLU 194.A O no hydrogen 2.933 N/A CYS 180.A N CYS 293.A O no hydrogen 2.837 N/A THR 181.A N TYR 192.A O no hydrogen 2.856 N/A THR 181.A OG1 ASN 292.A OD1 no hydrogen 2.806 N/A ARG 182.A N ILE 291.A O no hydrogen 2.764 N/A ARG 182.A NE PRO 183.A O no hydrogen 3.030 N/A ARG 182.A NH1 ILE 188.A O no hydrogen 2.875 N/A ARG 182.A NH1 ILE 287.A O no hydrogen 3.542 N/A ARG 182.A NH2 ILE 287.A O no hydrogen 2.792 N/A ARG 182.A NH2 GLY 289.A O no hydrogen 2.594 N/A SER 184.A OG ASN 185.A OD1 no hydrogen 2.782 N/A ARG 189.A N ASP 187.A OD1 no hydrogen 2.985 N/A ARG 189.A NE GLN 270.A OE1 no hydrogen 2.716 N/A LYS 190.A N ASP 187.A O no hydrogen 2.952 N/A ALA 191.A N CYS 266.A O no hydrogen 3.002 N/A TYR 192.A N THR 181.A O no hydrogen 2.988 N/A CYS 193.A N LEU 264.A O no hydrogen 3.014 N/A GLU 194.A N ASN 179.A O no hydrogen 2.843 N/A ILE 195.A N ILE 262.A O no hydrogen 2.918 N/A GLY 197.A N GLY 260.A O no hydrogen 2.841 N/A THR 198.A OG1 ASN 259.A O no hydrogen 2.792 N/A THR 198.A OG1 ASN 259.A OD1 no hydrogen 2.318 N/A LYS 199.A N ASN 196.A OD1 no hydrogen 3.133 N/A TRP 200.A N ASN 196.A O no hydrogen 2.967 N/A TRP 200.A NE1 LEU 251.A O no hydrogen 2.641 N/A ASN 201.A N GLY 197.A O no hydrogen 2.841 N/A LYS 202.A N THR 198.A O no hydrogen 3.131 N/A VAL 203.A N LYS 199.A O no hydrogen 3.225 N/A LEU 204.A N TRP 200.A O no hydrogen 2.753 N/A LYS 205.A N ASN 201.A O no hydrogen 2.773 N/A GLN 206.A N LYS 202.A O no hydrogen 3.035 N/A VAL 207.A N VAL 203.A O no hydrogen 2.897 N/A THR 208.A N LEU 204.A O no hydrogen 2.783 N/A THR 208.A OG1 LEU 204.A O no hydrogen 3.434 N/A GLU 209.A N LYS 205.A O no hydrogen 2.912 N/A LYS 210.A N GLN 206.A O no hydrogen 2.847 N/A LYS 210.A NZ GLU 153.A OE2 no hydrogen 3.325 N/A LYS 210.A NZ GLU 213.A OE2 no hydrogen 2.761 N/A LEU 211.A N VAL 207.A O no hydrogen 2.926 N/A LYS 212.A N THR 208.A O no hydrogen 2.946 N/A GLU 213.A N GLU 209.A O no hydrogen 3.350 N/A GLU 213.A N LYS 210.A O no hydrogen 2.977 N/A HIS 214.A N LEU 211.A O no hydrogen 2.942 N/A PHE 215.A N LYS 212.A O no hydrogen 3.320 N/A ASN 217.A N LYS 212.A O no hydrogen 2.808 N/A LYS 218.A N PHE 215.A O no hydrogen 2.845 N/A LYS 218.A NZ THR 308.A O no hydrogen 2.667 N/A THR 219.A N SER 309.A O no hydrogen 3.117 N/A ILE 221.A N GLU 311.A O no hydrogen 2.956 N/A PHE 222.A N ASN 254.A OD1 no hydrogen 2.868 N/A GLN 223.A N PHE 313.A O no hydrogen 2.978 N/A ILE 232.A N ASP 229.A O no hydrogen 2.911 N/A THR 233.A N ASP 229.A O no hydrogen 2.911 N/A THR 233.A OG1 ASP 229.A O no hydrogen 3.402 N/A MET 234.A N LEU 230.A O no hydrogen 3.033 N/A HIS 235.A N CYS 246.A O no hydrogen 2.879 N/A HIS 235.A ND1 THR 141.A O no hydrogen 2.807 N/A SER 236.A N THR 141.A OG1 no hydrogen 3.024 N/A SER 236.A OG THR 141.A OG1 no hydrogen 3.348 N/A SER 236.A OG GLU 231.A O no hydrogen 2.678 N/A PHE 237.A N PHE 244.A O no hydrogen 3.140 N/A CYS 239.A N GLU 242.A O no hydrogen 2.878 N/A ARG 240.A NE ASN 292.A O no hydrogen 2.951 N/A ARG 240.A NH2 ASN 292.A O no hydrogen 2.924 N/A GLY 241.A N ASN 238.A OD1 no hydrogen 2.791 N/A GLU 242.A N CYS 239.A O no hydrogen 3.019 N/A PHE 244.A N PHE 237.A O no hydrogen 2.969 N/A TYR 245.A N LYS 267.A O no hydrogen 2.922 N/A TYR 245.A OH GLU 231.A OE2 no hydrogen 2.615 N/A CYS 246.A N HIS 235.A O no hydrogen 2.750 N/A ASN 247.A N PRO 265.A O no hydrogen 2.852 N/A THR 248.A OG1 GLN 142.A OE1 no hydrogen 2.586 N/A THR 249.A N ASN 247.A OD1 no hydrogen 2.991 N/A THR 249.A OG1 ASN 247.A OD1 no hydrogen 3.164 N/A GLN 250.A NE2 THR 263.A O no hydrogen 2.604 N/A LEU 251.A N THR 248.A O no hydrogen 3.000 N/A ASN 254.A ND2 PHE 222.A O no hydrogen 2.892 N/A THR 255.A N ASN 253.A OD1 no hydrogen 3.152 N/A ILE 257.A N ASN 254.A O no hydrogen 3.334 N/A GLY 260.A N CYS 258.A O no hydrogen 2.530 N/A ILE 262.A N ILE 195.A O no hydrogen 2.747 N/A LEU 264.A N CYS 193.A O no hydrogen 2.851 N/A CYS 266.A N ALA 191.A O no hydrogen 2.957 N/A CYS 266.A SG LEU 264.A O no hydrogen 3.893 N/A LYS 267.A N TYR 245.A O no hydrogen 2.928 N/A ILE 268.A N ARG 189.A O no hydrogen 2.957 N/A LYS 269.A N PHE 243.A O no hydrogen 3.016 N/A LYS 269.A NZ ILE 271.A O no hydrogen 3.439 N/A GLN 270.A NE2 ILE 268.A O no hydrogen 3.107 N/A ILE 272.A N ALA 281.A O no hydrogen 2.841 N/A ASN 273.A N GLU 231.A OE2 no hydrogen 2.921 N/A ASN 273.A ND2 GLU 231.A OE1 no hydrogen 2.952 N/A MET 274.A N GLY 279.A O no hydrogen 2.988 N/A GLN 276.A N GLN 276.A OE1 no hydrogen 2.786 N/A GLN 276.A NE2 ASP 70.A OD1 no hydrogen 2.831 N/A GLN 280.A N LEU 79.A O no hydrogen 2.876 N/A ALA 281.A N ILE 272.A O no hydrogen 2.887 N/A MET 282.A N VAL 77.A O no hydrogen 2.839 N/A TYR 283.A N GLN 270.A O no hydrogen 2.800 N/A ILE 287.A N GLU 242.A OE2 no hydrogen 3.134 N/A ILE 291.A N ARG 182.A O no hydrogen 2.842 N/A CYS 293.A N CYS 180.A O no hydrogen 3.011 N/A SER 295.A N ILE 178.A O no hydrogen 2.934 N/A ASN 296.A N ASN 146.A OD1 no hydrogen 3.018 N/A ILE 297.A N VAL 176.A O no hydrogen 2.766 N/A THR 298.A N LEU 144.A O no hydrogen 2.895 N/A THR 298.A OG1 LEU 144.A O no hydrogen 3.464 N/A GLY 299.A N LEU 144.A O no hydrogen 3.263 N/A ILE 300.A N VAL 170.A O no hydrogen 3.049 N/A LEU 301.A N GLN 142.A O no hydrogen 2.838 N/A LEU 302.A N ILE 168.A O no hydrogen 2.873 N/A THR 303.A N ARG 314.A O no hydrogen 2.803 N/A ARG 304.A NH1 GLU 311.A OE1 no hydrogen 2.922 N/A ARG 304.A NH2 LEU 161.A O no hydrogen 3.143 N/A ASP 305.A N THR 312.A O no hydrogen 2.789 N/A GLU 311.A N THR 219.A O no hydrogen 2.869 N/A PHE 313.A N ILE 221.A O no hydrogen 2.846 N/A ARG 314.A N THR 303.A O no hydrogen 2.844 N/A ARG 314.A NE ASP 305.A OD1 no hydrogen 2.743 N/A ARG 314.A NE ASP 305.A OD2 no hydrogen 3.374 N/A ARG 314.A NH1 PRO 224.A O no hydrogen 2.863 N/A ARG 314.A NH2 ASP 305.A OD2 no hydrogen 2.810 N/A GLY 316.A N LEU 301.A O no hydrogen 2.702 N/A LYS 321.A N ASN 319.A OD1 no hydrogen 3.278 N/A ASP 322.A N ASN 319.A O no hydrogen 2.811 N/A ASN 323.A ND2 SER 140.A O no hydrogen 3.004 N/A TRP 324.A N ILE 320.A O no hydrogen 3.313 N/A TRP 324.A NE1 GLN 62.A OE1 no hydrogen 2.879 N/A ARG 325.A N LYS 321.A O no hydrogen 2.990 N/A ARG 325.A NH1 ASP 322.A OD1 no hydrogen 2.732 N/A SER 326.A N ASP 322.A O no hydrogen 3.198 N/A SER 326.A N ASN 323.A O no hydrogen 3.221 N/A SER 326.A OG ASN 323.A O no hydrogen 2.580 N/A GLU 327.A N TRP 324.A O no hydrogen 3.035 N/A LEU 328.A N TRP 324.A O no hydrogen 2.927 N/A TYR 331.A N LEU 328.A O no hydrogen 2.857 N/A TYR 331.A OH HIS 133.A ND1 no hydrogen 2.612 N/A LYS 332.A N LEU 110.A O no hydrogen 2.833 N/A LYS 332.A NZ ASP 4.A OD1 no hydrogen 2.663 N/A LYS 332.A NZ ASP 4.A OD2 no hydrogen 3.551 N/A LYS 332.A NZ GLU 48.A OE2 no hydrogen 3.127 N/A LYS 332.A NZ ASN 49.A O no hydrogen 2.639 N/A VAL 334.A N VAL 108.A O no hydrogen 2.994 N/A GLN 335.A N LYS 3.A O no hydrogen 2.797 N/A GLN 335.A NE2 GLU 337.A OE1 no hydrogen 3.209 N/A ILE 336.A N GLY 106.A O no hydrogen 2.918 N/A GLU 337.A N GLY 106.A O no hydrogen 3.234 N/A