Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4han_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 4.A N.A SER 292.A O no hydrogen 2.692 N/A MET 4.A N.B SER 292.A O no hydrogen 2.707 N/A SER 6.A N VAL 290.A O no hydrogen 2.740 N/A LEU 10.A N PHE 155.A O no hydrogen 2.695 N/A GLN 11.A NE2 SER 154.A OG no hydrogen 3.405 N/A ASN 12.A N PHE 153.A O no hydrogen 2.912 N/A ILE 14.A N ILE 151.A O no hydrogen 2.749 N/A ASN 16.A N HIS 149.A O no hydrogen 2.645 N/A PHE 21.A N ILE 142.A O no hydrogen 2.970 N/A GLY 23.A N LEU 140.A O no hydrogen 2.937 N/A ILE 25.A N ASP 138.A O no hydrogen 2.780 N/A GLN 28.A N ASP 27.A OD1 no hydrogen 2.545 N/A ASP 30.A N GLN 28.A O no hydrogen 3.066 N/A GLY 32.A N VAL 111.A O no hydrogen 2.678 N/A THR 33.A N ASP 30.A O no hydrogen 3.091 N/A THR 33.A OG1 ASP 30.A O no hydrogen 2.797 N/A LEU 34.A N SER 154.A O no hydrogen 3.143 N/A ILE 35.A N ILE 109.A O no hydrogen 2.886 N/A VAL 36.A N GLY 152.A O no hydrogen 2.678 N/A ILE 37.A N ILE 107.A O no hydrogen 2.860 N/A ARG 38.A N SER 150.A O no hydrogen 3.132 N/A GLY 39.A N PHE 105.A O no hydrogen 3.117 N/A HIS 40.A N ASN 147.A O no hydrogen 2.829 N/A VAL 41.A N LYS 103.A O no hydrogen 3.152 N/A ALA 45.A N PRO 42.A O no hydrogen 3.271 N/A ARG 47.A NH2 GLN 49.A OE1 no hydrogen 2.858 N/A PHE 48.A N PRO 70.A O no hydrogen 3.280 N/A GLN 49.A N TYR 143.A O no hydrogen 2.821 N/A GLN 49.A NE2 ASP 51.A OD1 no hydrogen 2.582 N/A VAL 50.A N PHE 68.A O no hydrogen 2.855 N/A ASP 51.A N GLY 141.A O no hydrogen 2.659 N/A LEU 52.A N PHE 66.A O no hydrogen 2.825 N/A GLN 53.A N THR 139.A O no hydrogen 2.700 N/A GLN 53.A NE2 TYR 143.A OH no hydrogen 2.639 N/A ASN 54.A N ASP 63.A O no hydrogen 2.883 N/A GLY 55.A N ASP 138.A OD2 no hydrogen 2.851 N/A SER 57.A OG PRO 60.A O no hydrogen 2.583 N/A ARG 61.A N GLU 86.A OE2 no hydrogen 2.533 N/A ALA 62.A N SER 57.A O no hydrogen 2.866 N/A VAL 64.A N LEU 83.A O no hydrogen 2.824 N/A PHE 66.A N LEU 52.A O no hydrogen 3.357 N/A HIS 67.A N ASN 81.A O no hydrogen 2.854 N/A HIS 67.A ND1 ASP 51.A OD2 no hydrogen 2.574 N/A PHE 68.A N VAL 50.A O no hydrogen 2.924 N/A ASN 69.A N VAL 79.A O no hydrogen 2.697 N/A ASN 69.A ND2 PHE 48.A O no hydrogen 2.714 N/A ARG 71.A N CYS 77.A O no hydrogen 2.743 N/A ARG 71.A NE ASN 69.A OD1 no hydrogen 2.916 N/A ARG 71.A NH2 ASN 69.A OD1 no hydrogen 3.035 N/A PHE 72.A N ASP 46.A O no hydrogen 2.863 N/A GLY 76.A N LYS 73.A O no hydrogen 3.182 N/A CYS 77.A N ARG 71.A O no hydrogen 3.042 N/A ILE 78.A N THR 94.A O no hydrogen 2.932 N/A VAL 79.A N ASN 69.A O no hydrogen 2.792 N/A CYS 80.A N GLU 92.A O no hydrogen 2.732 N/A ASN 81.A N HIS 67.A O no hydrogen 3.166 N/A ASN 81.A ND2 GLY 89.A O no hydrogen 2.851 N/A THR 82.A N ASN 81.A OD1 no hydrogen 2.682 N/A THR 82.A OG1 ALA 65.A O no hydrogen 2.689 N/A THR 82.A OG1 TYR 128.A OH no hydrogen 2.582 N/A LEU 83.A N VAL 64.A O no hydrogen 2.865 N/A ILE 84.A N LYS 87.A O no hydrogen 2.857 N/A ASN 85.A N ASP 63.A OD1 no hydrogen 2.772 N/A LYS 87.A N ILE 84.A O no hydrogen 2.885 N/A GLY 89.A N THR 82.A O no hydrogen 2.974 N/A GLU 92.A N CYS 80.A O no hydrogen 2.809 N/A THR 94.A N ILE 78.A O no hydrogen 2.986 N/A ARG 101.A NE ALA 45.A O no hydrogen 2.653 N/A ARG 101.A NH2 ALA 45.A O no hydrogen 3.369 N/A ARG 101.A NH2 ASP 46.A OD2 no hydrogen 3.101 N/A GLU 102.A N VAL 41.A O no hydrogen 2.665 N/A LYS 103.A N LYS 100.A O no hydrogen 3.265 N/A PHE 105.A N GLY 39.A O no hydrogen 3.091 N/A GLU 106.A N ASN 121.A OD1 no hydrogen 3.004 N/A ILE 107.A N ILE 37.A O no hydrogen 2.771 N/A VAL 108.A N ALA 119.A O no hydrogen 2.729 N/A ILE 109.A N ILE 35.A O no hydrogen 2.829 N/A MET 110.A N GLN 117.A O no hydrogen 2.748 N/A VAL 111.A N THR 33.A O no hydrogen 2.863 N/A LEU 112.A N LYS 115.A O no hydrogen 2.863 N/A PHE 116.A N TYR 128.A O no hydrogen 2.766 N/A GLN 117.A N MET 110.A O no hydrogen 2.848 N/A VAL 118.A N LEU 126.A O no hydrogen 2.935 N/A ALA 119.A N VAL 108.A O no hydrogen 2.873 N/A VAL 120.A N LYS 123.A O no hydrogen 2.989 N/A ASN 121.A N GLU 106.A O no hydrogen 3.006 N/A LYS 123.A N VAL 120.A O no hydrogen 3.150 N/A THR 125.A N VAL 118.A O no hydrogen 2.886 N/A THR 125.A OG1 LYS 123.A O no hydrogen 3.408 N/A LEU 126.A N VAL 118.A O no hydrogen 3.226 N/A TYR 128.A N PHE 116.A O no hydrogen 3.010 N/A TYR 128.A OH THR 82.A OG1 no hydrogen 2.582 N/A HIS 130.A N ASP 114.A O no hydrogen 3.141 N/A HIS 130.A NE2 LEU 112.A O no hydrogen 2.861 N/A ARG 131.A NH1 ASN 81.A OD1 no hydrogen 3.105 N/A ARG 131.A NH1 ARG 90.A O no hydrogen 3.034 N/A ARG 131.A NH2 ARG 90.A O no hydrogen 2.750 N/A ARG 131.A NH2 GLU 92.A OE2 no hydrogen 2.976 N/A GLU 135.A N GLU 135.A OE1 no hydrogen 2.856 N/A LYS 136.A N GLY 133.A O no hydrogen 2.899 N/A ILE 137.A N PRO 134.A O no hydrogen 3.293 N/A ASP 138.A N GLN 53.A O no hydrogen 3.085 N/A THR 139.A N GLN 53.A O no hydrogen 3.127 N/A THR 139.A OG1 ASP 138.A OD2 no hydrogen 2.687 N/A LEU 140.A N GLY 23.A O no hydrogen 2.778 N/A GLY 141.A N ASP 51.A O no hydrogen 2.809 N/A ILE 142.A N PHE 21.A O no hydrogen 2.977 N/A TYR 143.A N GLN 49.A O no hydrogen 3.051 N/A LYS 145.A N ARG 47.A O no hydrogen 3.110 N/A ASN 147.A N HIS 40.A O no hydrogen 2.917 N/A HIS 149.A N ARG 38.A O no hydrogen 2.885 N/A SER 150.A N ARG 38.A O no hydrogen 3.414 N/A ILE 151.A N ILE 14.A O no hydrogen 2.910 N/A GLY 152.A N VAL 36.A O no hydrogen 2.600 N/A PHE 153.A N ASN 12.A O no hydrogen 2.741 N/A SER 154.A N LEU 34.A O no hydrogen 2.990 N/A PHE 155.A N LEU 10.A O no hydrogen 2.744 N/A MET 159.A N LEU 287.A O no hydrogen 2.898 N/A PHE 163.A N ILE 281.A O no hydrogen 2.849 N/A ALA 165.A N LEU 279.A O no hydrogen 2.831 N/A LEU 167.A N ASP 277.A O no hydrogen 2.930 N/A MET 171.A N ILE 276.A O no hydrogen 2.844 N/A GLY 174.A N CYS 249.A O no hydrogen 2.590 N/A ARG 175.A N GLY 172.A O no hydrogen 2.980 N/A ARG 175.A NE PRO 170.A O no hydrogen 3.020 N/A ARG 175.A NH1 SER 292.A OG no hydrogen 2.911 N/A ARG 175.A NH1 TRP 293.A O no hydrogen 2.657 N/A ARG 175.A NH2 THR 169.A O no hydrogen 2.854 N/A ARG 175.A NH2 SER 292.A OG no hydrogen 3.315 N/A THR 176.A N TRP 293.A O no hydrogen 2.893 N/A VAL 177.A N ILE 247.A O no hydrogen 2.826 N/A VAL 178.A N ARG 291.A O no hydrogen 2.649 N/A VAL 179.A N MET 245.A O no hydrogen 2.907 N/A LYS 180.A N GLU 289.A O no hydrogen 2.722 N/A LYS 180.A NZ GLU 289.A OE2 no hydrogen 2.664 N/A GLY 181.A N PHE 243.A O no hydrogen 3.151 N/A GLU 182.A N HIS 286.A O no hydrogen 2.789 N/A VAL 183.A N MET 241.A O no hydrogen 3.058 N/A ASN 184.A N ASP 284.A O no hydrogen 3.110 N/A ALA 187.A N ASN 184.A O no hydrogen 3.095 N/A LYS 188.A N ASP 284.A OD1 no hydrogen 2.819 N/A PHE 190.A N PRO 208.A O no hydrogen 3.302 N/A ASN 191.A N ASN 282.A O no hydrogen 2.840 N/A ASN 191.A ND2 ASP 193.A OD2 no hydrogen 3.083 N/A VAL 192.A N LEU 206.A O no hydrogen 2.768 N/A ASP 193.A N GLU 280.A O no hydrogen 2.775 N/A LEU 194.A N LEU 204.A O no hydrogen 3.004 N/A LEU 195.A N THR 278.A O no hydrogen 2.900 N/A ALA 196.A N ASP 201.A O no hydrogen 2.899 N/A GLY 197.A N ASP 277.A OD2 no hydrogen 2.753 N/A SER 199.A OG ASP 201.A OD2 no hydrogen 2.948 N/A LYS 200.A N ALA 196.A O no hydrogen 2.793 N/A ASP 201.A N SER 199.A OG no hydrogen 3.403 N/A ILE 202.A N PHE 220.A O no hydrogen 3.033 N/A ALA 203.A N LEU 194.A O no hydrogen 2.861 N/A LEU 204.A N LEU 194.A O no hydrogen 3.308 N/A HIS 205.A N ASN 218.A O no hydrogen 2.853 N/A HIS 205.A ND1 ASP 193.A OD1 no hydrogen 2.539 N/A LEU 206.A N VAL 192.A O no hydrogen 2.786 N/A ASN 207.A N VAL 216.A O no hydrogen 2.843 N/A ASN 207.A ND2 PHE 190.A O no hydrogen 3.029 N/A ARG 209.A N ALA 214.A O no hydrogen 2.690 N/A ARG 209.A NE ASN 207.A OD1 no hydrogen 2.924 N/A ARG 209.A NH2 ASN 207.A OD1 no hydrogen 3.475 N/A LEU 210.A N LYS 188.A O no hydrogen 2.719 N/A ASN 211.A N LYS 188.A O no hydrogen 3.220 N/A LYS 213.A N LEU 210.A O no hydrogen 3.145 N/A ALA 214.A N ARG 209.A O no hydrogen 3.067 N/A VAL 216.A N ASN 207.A O no hydrogen 2.984 N/A ARG 217.A N GLU 229.A O no hydrogen 3.089 N/A ARG 217.A NE PHE 215.A O no hydrogen 3.222 N/A ARG 217.A NH1 ASN 231.A O no hydrogen 3.219 N/A ARG 217.A NH2 PHE 215.A O no hydrogen 3.296 N/A ARG 217.A NH2 ASN 231.A O no hydrogen 2.439 N/A ASN 218.A N HIS 205.A O no hydrogen 3.274 N/A ASN 218.A ND2 GLY 226.A O no hydrogen 2.986 N/A SER 219.A N ASN 218.A OD1 no hydrogen 2.891 N/A SER 219.A OG ALA 203.A O no hydrogen 2.592 N/A SER 219.A OG TYR 266.A OH no hydrogen 2.702 N/A PHE 220.A N ILE 202.A O no hydrogen 2.910 N/A LEU 221.A N SER 224.A O no hydrogen 2.917 N/A SER 224.A N LEU 221.A O no hydrogen 3.010 N/A SER 224.A OG TRP 225.A O no hydrogen 3.468 N/A GLY 226.A N SER 219.A O no hydrogen 3.120 N/A GLU 229.A N ARG 217.A O no hydrogen 2.965 N/A ARG 230.A NE GLU 228.A OE1 no hydrogen 2.977 N/A ARG 230.A NH2 GLU 228.A OE1 no hydrogen 2.990 N/A GLY 240.A N VAL 183.A O no hydrogen 2.850 N/A MET 241.A N SER 238.A O no hydrogen 3.113 N/A TYR 242.A OH GLU 244.A OE1 no hydrogen 2.667 N/A PHE 243.A N GLY 181.A O no hydrogen 2.939 N/A GLU 244.A N ASN 259.A OD1 no hydrogen 2.994 N/A MET 245.A N VAL 179.A O no hydrogen 2.935 N/A ILE 246.A N ALA 257.A O no hydrogen 2.865 N/A ILE 247.A N VAL 177.A O no hydrogen 2.714 N/A TYR 248.A N LYS 255.A O no hydrogen 2.793 N/A CYS 249.A N ARG 175.A O no hydrogen 2.741 N/A CYS 249.A SG ASP 250.A O no hydrogen 3.745 N/A CYS 249.A SG HIS 268.A NE2 no hydrogen 3.873 N/A ASP 250.A N GLU 253.A O no hydrogen 2.830 N/A VAL 251.A N ASP 250.A OD1 no hydrogen 2.703 N/A PHE 254.A N TYR 266.A O no hydrogen 2.745 N/A LYS 255.A N TYR 248.A O no hydrogen 2.871 N/A LYS 255.A NZ ASP 250.A OD2 no hydrogen 3.345 N/A VAL 256.A N LEU 264.A O no hydrogen 2.938 N/A ALA 257.A N ILE 246.A O no hydrogen 2.960 N/A VAL 258.A N VAL 261.A O no hydrogen 2.931 N/A ASN 259.A N GLU 244.A O no hydrogen 2.889 N/A VAL 261.A N VAL 258.A O no hydrogen 3.424 N/A SER 263.A N VAL 256.A O no hydrogen 2.847 N/A LEU 264.A N VAL 256.A O no hydrogen 3.225 N/A TYR 266.A N PHE 254.A O no hydrogen 2.906 N/A TYR 266.A OH SER 219.A OG no hydrogen 2.702 N/A LYS 267.A NZ GLU 253.A OE1 no hydrogen 3.122 N/A HIS 268.A N ARG 252.A O no hydrogen 2.970 N/A HIS 268.A NE2 ASP 250.A O no hydrogen 2.955 N/A ARG 269.A NH1 ASN 218.A OD1 no hydrogen 3.109 N/A ARG 269.A NH1 GLU 227.A O no hydrogen 3.114 N/A ARG 269.A NH2 GLU 227.A O no hydrogen 2.739 N/A ARG 269.A NH2 GLU 229.A OE2 no hydrogen 2.856 N/A LYS 271.A NZ HIS 268.A O no hydrogen 2.982 N/A SER 275.A N GLU 272.A O no hydrogen 2.991 N/A ILE 276.A N LEU 273.A O no hydrogen 2.853 N/A ASP 277.A N LEU 195.A O no hydrogen 3.017 N/A THR 278.A N LEU 195.A O no hydrogen 3.230 N/A THR 278.A OG1 ASP 277.A OD2 no hydrogen 2.810 N/A LEU 279.A N ALA 165.A O no hydrogen 2.716 N/A GLU 280.A N ASP 193.A O no hydrogen 2.851 N/A ILE 281.A N PHE 163.A O no hydrogen 2.967 N/A ASN 282.A N ASN 191.A O no hydrogen 3.111 N/A GLY 283.A N ASN 282.A OD1 no hydrogen 2.728 N/A ASP 284.A N SER 189.A O no hydrogen 3.045 N/A ILE 285.A N GLY 283.A O no hydrogen 2.882 N/A HIS 286.A N GLU 182.A O no hydrogen 2.604 N/A LEU 288.A N LYS 180.A O no hydrogen 2.757 N/A GLU 289.A N LYS 180.A O no hydrogen 3.074 N/A VAL 290.A N SER 6.A O no hydrogen 3.007 N/A ARG 291.A N VAL 178.A O no hydrogen 2.827 N/A ARG 291.A NH1 GLU 289.A OE2 no hydrogen 2.997 N/A SER 292.A N MET 4.A O.A no hydrogen 3.072 N/A SER 292.A N MET 4.A O.B no hydrogen 2.961 N/A TRP 293.A N THR 176.A O no hydrogen 2.986 N/A