Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4hna_K.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 3.A OG GLU 2.A O no hydrogen 2.874 N/A ASN 4.A ND2 LYS 319.A O no hydrogen 3.375 N/A ILE 5.A N ILE 321.A O no hydrogen 2.843 N/A LYS 6.A N THR 292.A O no hydrogen 2.933 N/A VAL 7.A N ASP 45.A OD1 no hydrogen 3.046 N/A MET 8.A N ILE 294.A O no hydrogen 2.882 N/A CYS 9.A N ARG 46.A O no hydrogen 3.166 N/A CYS 9.A SG ILE 296.A O no hydrogen 3.726 N/A ARG 10.A N ILE 296.A O no hydrogen 2.863 N/A ARG 10.A NH1 HIS 89.A ND1 no hydrogen 3.512 N/A ARG 10.A NH1 THR 90.A OG1 no hydrogen 2.775 N/A ARG 10.A NH2 GLN 54.A OE1 no hydrogen 2.725 N/A PHE 11.A N PHE 48.A O no hydrogen 3.268 N/A ARG 12.A N CYS 298.A O no hydrogen 3.398 N/A ARG 12.A NE SER 84.A O no hydrogen 2.750 N/A ARG 12.A NH1 PRO 13.A O no hydrogen 3.397 N/A ARG 12.A NH1 GLU 18.A OE1 no hydrogen 2.969 N/A ARG 12.A NH1 GLU 18.A OE2 no hydrogen 3.537 N/A ARG 12.A NH2 GLU 18.A OE2 no hydrogen 3.288 N/A ARG 12.A NH2 SER 84.A O no hydrogen 2.833 N/A ASN 15.A N GLU 18.A OE1 no hydrogen 2.998 N/A GLU 18.A N ASN 15.A OD1 no hydrogen 2.834 N/A VAL 19.A N ASN 15.A O no hydrogen 2.972 N/A ASN 20.A N GLU 16.A O no hydrogen 2.692 N/A ARG 21.A N GLU 18.A O no hydrogen 3.177 N/A ARG 21.A NE ASP 23.A OD1 no hydrogen 3.022 N/A ARG 21.A NE ASP 23.A OD2 no hydrogen 3.221 N/A ARG 21.A NH2 ASP 23.A OD2 no hydrogen 2.882 N/A LYS 24.A N SER 302.A OG no hydrogen 3.034 N/A TYR 25.A OH SER 50.A OG no hydrogen 2.734 N/A ILE 26.A N PRO 300.A O no hydrogen 2.784 N/A LYS 28.A N VAL 36.A O no hydrogen 3.341 N/A GLN 30.A N THR 34.A O no hydrogen 2.951 N/A THR 34.A N GLN 30.A O no hydrogen 3.001 N/A THR 34.A OG1 ASP 33.A OD1 no hydrogen 3.563 N/A VAL 35.A N TYR 42.A O no hydrogen 3.150 N/A VAL 36.A N LYS 28.A O no hydrogen 2.709 N/A ILE 37.A N LYS 40.A O no hydrogen 3.048 N/A LYS 40.A N ILE 37.A O no hydrogen 3.303 N/A LYS 40.A NZ PRO 41.A O no hydrogen 3.456 N/A TYR 42.A N VAL 35.A O no hydrogen 2.795 N/A PHE 44.A N ASP 33.A O no hydrogen 2.992 N/A ASP 45.A N VAL 7.A O no hydrogen 2.910 N/A ARG 46.A NE VAL 47.A O no hydrogen 3.333 N/A VAL 47.A N GLU 32.A O no hydrogen 2.925 N/A PHE 48.A N CYS 9.A O no hydrogen 2.715 N/A SER 50.A OG TYR 25.A OH no hydrogen 2.734 N/A THR 52.A N GLN 49.A O no hydrogen 3.119 N/A THR 52.A OG1 GLN 49.A O no hydrogen 3.273 N/A SER 53.A N GLN 56.A OE1 no hydrogen 2.854 N/A GLN 54.A NE2 HIS 89.A O no hydrogen 2.974 N/A GLN 54.A NE2 GLY 100.A O no hydrogen 3.318 N/A GLN 54.A NE2 MET 101.A O no hydrogen 3.219 N/A GLU 55.A N SER 53.A OG no hydrogen 3.118 N/A GLN 56.A N SER 53.A OG no hydrogen 3.094 N/A VAL 57.A N SER 53.A O no hydrogen 2.931 N/A TYR 58.A N GLN 54.A O no hydrogen 3.106 N/A TYR 58.A OH ASP 110.A OD2 no hydrogen 3.193 N/A ASN 59.A N GLU 55.A O no hydrogen 3.048 N/A ASP 60.A N GLN 56.A O no hydrogen 3.257 N/A ASP 60.A N VAL 57.A O no hydrogen 3.260 N/A ALA 61.A N VAL 57.A O no hydrogen 2.854 N/A ALA 62.A N TYR 58.A O no hydrogen 3.029 N/A LYS 64.A N ALA 62.A O no hydrogen 2.556 N/A LYS 64.A NZ ASN 59.A O no hydrogen 2.895 N/A LYS 64.A NZ ASP 60.A O no hydrogen 3.248 N/A ASP 68.A N LYS 64.A O no hydrogen 3.321 N/A VAL 69.A N ILE 65.A O no hydrogen 2.936 N/A LEU 70.A N VAL 66.A O no hydrogen 3.215 N/A GLU 71.A N LYS 67.A O no hydrogen 2.897 N/A GLY 72.A N VAL 69.A O no hydrogen 3.133 N/A TYR 73.A N ASP 68.A O no hydrogen 2.943 N/A ASN 74.A ND2 ASN 289.A O no hydrogen 2.875 N/A ASN 74.A ND2 ASN 328.A OD1 no hydrogen 3.215 N/A GLY 75.A N LYS 222.A O no hydrogen 3.001 N/A THR 76.A N ARG 291.A O no hydrogen 3.055 N/A THR 76.A OG1 SER 285.A OG no hydrogen 3.046 N/A ILE 77.A N TYR 224.A O no hydrogen 3.048 N/A PHE 78.A N THR 293.A O no hydrogen 3.272 N/A ALA 79.A N VAL 226.A O no hydrogen 3.153 N/A TYR 80.A N VAL 295.A O no hydrogen 2.899 N/A GLN 82.A NE2 ASN 304.A OD1 no hydrogen 3.093 N/A THR 83.A N SER 231.A O no hydrogen 3.027 N/A SER 84.A OG THR 83.A O no hydrogen 2.756 N/A SER 84.A OG MET 193.A O no hydrogen 2.893 N/A SER 85.A N GLN 82.A O no hydrogen 3.102 N/A SER 85.A OG GLN 82.A O no hydrogen 2.694 N/A SER 85.A OG CYS 297.A O no hydrogen 3.504 N/A LYS 87.A NZ GLY 81.A O no hydrogen 3.317 N/A THR 88.A OG1 SER 198.A OG no hydrogen 2.826 N/A THR 88.A OG1 ASP 227.A OD1 no hydrogen 2.696 N/A THR 88.A OG1 ASP 227.A OD2 no hydrogen 3.206 N/A THR 90.A N GLY 86.A O no hydrogen 2.827 N/A THR 90.A OG1 GLY 86.A O no hydrogen 2.521 N/A MET 91.A N LYS 87.A O no hydrogen 3.024 N/A GLU 92.A N THR 88.A O no hydrogen 2.714 N/A GLY 93.A N THR 88.A O no hydrogen 3.222 N/A LYS 94.A N GLY 100.A O no hydrogen 2.956 N/A LYS 94.A NZ ASP 97.A OD1 no hydrogen 3.191 N/A LEU 95.A N GLY 93.A O no hydrogen 2.926 N/A MET 101.A N ASP 97.A O no hydrogen 2.874 N/A GLY 102.A N GLU 92.A O no hydrogen 2.879 N/A ILE 103.A N THR 90.A O no hydrogen 2.970 N/A ILE 104.A N MET 91.A O no hydrogen 3.078 N/A ARG 106.A NE MET 101.A O no hydrogen 2.908 N/A ARG 106.A NE GLY 102.A O no hydrogen 3.273 N/A ARG 106.A NH2 MET 101.A O no hydrogen 2.969 N/A ILE 107.A N ILE 103.A O no hydrogen 2.796 N/A VAL 108.A N ILE 104.A O no hydrogen 3.071 N/A GLN 109.A N PRO 105.A O no hydrogen 3.358 N/A ASP 110.A N ARG 106.A O no hydrogen 3.143 N/A ILE 111.A N ILE 107.A O no hydrogen 2.839 N/A ASN 113.A N GLN 109.A O no hydrogen 2.967 N/A TYR 114.A N ASP 110.A O no hydrogen 3.271 N/A ILE 115.A N ILE 111.A O no hydrogen 3.192 N/A TYR 116.A N PHE 112.A O no hydrogen 2.850 N/A SER 117.A OG ASN 113.A O no hydrogen 2.921 N/A MET 118.A N TYR 114.A O no hydrogen 2.967 N/A ASN 121.A N ASP 119.A OD1 no hydrogen 3.481 N/A LEU 122.A N ASP 119.A O no hydrogen 3.179 N/A GLU 123.A N GLU 211.A O no hydrogen 2.949 N/A HIS 125.A N LYS 209.A O no hydrogen 2.823 N/A LYS 127.A N ASN 207.A O no hydrogen 3.140 N/A LYS 127.A NZ GLU 166.A OE1 no hydrogen 2.708 N/A LYS 127.A NZ GLU 166.A OE2 no hydrogen 3.497 N/A VAL 128.A N ARG 167.A O no hydrogen 2.795 N/A SER 129.A N LEU 205.A O no hydrogen 3.104 N/A SER 129.A OG THR 165.A O no hydrogen 2.696 N/A PHE 131.A N ILE 203.A O no hydrogen 3.061 N/A GLU 132.A N ARG 139.A O no hydrogen 2.912 N/A ILE 133.A N HIS 201.A O no hydrogen 3.215 N/A TYR 134.A N LYS 137.A O no hydrogen 3.235 N/A TYR 134.A OH GLU 246.A OE2 no hydrogen 2.492 N/A LYS 137.A N TYR 134.A O no hydrogen 3.123 N/A ARG 139.A N GLU 132.A O no hydrogen 2.886 N/A ARG 139.A NH1 GLU 132.A OE2 no hydrogen 2.789 N/A ASP 140.A N LYS 146.A O no hydrogen 2.856 N/A LEU 141.A N TYR 130.A O no hydrogen 2.945 N/A LEU 142.A N ASP 140.A OD1 no hydrogen 3.276 N/A SER 145.A N ASP 143.A OD1 no hydrogen 2.870 N/A SER 145.A OG ASP 143.A OD1 no hydrogen 3.011 N/A SER 145.A OG ASP 143.A OD2 no hydrogen 3.487 N/A LYS 146.A NZ GLY 163.A O no hydrogen 3.036 N/A LEU 149.A N ILE 138.A O no hydrogen 2.784 N/A HIS 152.A N TYR 160.A O no hydrogen 2.761 N/A ASP 154.A N VAL 158.A O no hydrogen 3.065 N/A ARG 157.A N ASP 154.A O no hydrogen 2.890 N/A VAL 158.A N ASP 154.A OD1 no hydrogen 3.061 N/A TYR 160.A N HIS 152.A O no hydrogen 2.748 N/A LYS 162.A N SER 150.A O no hydrogen 2.853 N/A THR 165.A N ASP 140.A OD2 no hydrogen 2.901 N/A THR 165.A OG1 ASP 140.A OD2 no hydrogen 2.671 N/A ARG 167.A N VAL 128.A O no hydrogen 2.958 N/A ARG 167.A NH1 GLU 181.A OE1 no hydrogen 3.235 N/A ARG 167.A NH1 GLU 181.A OE2 no hydrogen 3.072 N/A ARG 167.A NH2 GLU 181.A OE1 no hydrogen 3.392 N/A VAL 169.A N ILE 126.A O no hydrogen 2.949 N/A GLU 174.A N SER 171.A OG no hydrogen 2.977 N/A VAL 175.A N SER 171.A O no hydrogen 3.397 N/A VAL 175.A N PRO 172.A O no hydrogen 3.046 N/A MET 176.A N PRO 172.A O no hydrogen 3.005 N/A ASP 177.A N ASP 173.A O no hydrogen 3.103 N/A THR 178.A OG1 VAL 175.A O no hydrogen 3.246 N/A ILE 179.A N VAL 175.A O no hydrogen 2.852 N/A ASP 180.A N MET 176.A O no hydrogen 2.826 N/A GLU 181.A N ASP 177.A O no hydrogen 3.062 N/A GLY 182.A N THR 178.A O no hydrogen 2.932 N/A LYS 183.A N ILE 179.A O no hydrogen 2.757 N/A LYS 183.A NZ GLU 92.A OE1 no hydrogen 2.752 N/A SER 184.A N ASP 180.A O no hydrogen 3.137 N/A SER 184.A OG ASP 180.A O no hydrogen 2.793 N/A SER 184.A OG GLU 181.A O no hydrogen 2.738 N/A ASN 185.A N GLY 182.A O no hydrogen 3.128 N/A ASN 185.A ND2 LEU 141.A O no hydrogen 3.252 N/A ARG 186.A N GLY 182.A O no hydrogen 3.277 N/A ARG 186.A N LYS 183.A O no hydrogen 3.043 N/A ARG 186.A NE SER 200.A OG no hydrogen 2.989 N/A ARG 186.A NH1 ASP 227.A OD1 no hydrogen 2.770 N/A ARG 186.A NH2 SER 200.A O no hydrogen 2.508 N/A ARG 186.A NH2 ASP 227.A O no hydrogen 3.348 N/A HIS 187.A N GLU 132.A OE1 no hydrogen 3.034 N/A ALA 189.A N SER 197.A O no hydrogen 2.960 N/A THR 191.A N ASN 194.A O no hydrogen 2.965 N/A ASN 192.A N THR 237.A O no hydrogen 2.620 N/A ASN 194.A N THR 191.A O no hydrogen 3.184 N/A ASN 194.A N THR 191.A OG1 no hydrogen 3.155 N/A HIS 196.A N ASN 194.A OD1 no hydrogen 3.248 N/A SER 197.A N ALA 189.A O no hydrogen 2.966 N/A SER 198.A OG THR 88.A OG1 no hydrogen 2.826 N/A ARG 199.A N HIS 187.A O no hydrogen 2.965 N/A ARG 199.A NE SER 198.A O no hydrogen 3.469 N/A ARG 199.A NH1 GLU 232.A OE2 no hydrogen 3.473 N/A ARG 199.A NH2 SER 197.A OG no hydrogen 3.022 N/A ARG 199.A NH2 GLU 232.A OE2 no hydrogen 2.858 N/A SER 200.A OG GLU 132.A OE1 no hydrogen 2.887 N/A HIS 201.A N ILE 133.A O no hydrogen 3.387 N/A HIS 201.A NE2 SER 253.A OG no hydrogen 2.802 N/A SER 202.A N ASP 227.A O no hydrogen 2.837 N/A ILE 203.A N PHE 131.A O no hydrogen 2.831 N/A PHE 204.A N LEU 225.A O no hydrogen 3.212 N/A LEU 205.A N SER 129.A O no hydrogen 3.032 N/A ILE 206.A N LEU 223.A O no hydrogen 2.880 N/A ASN 207.A N LYS 127.A O no hydrogen 2.986 N/A VAL 208.A N GLY 221.A O no hydrogen 3.002 N/A LYS 209.A N HIS 125.A O no hydrogen 3.001 N/A GLN 210.A N LEU 219.A O no hydrogen 2.892 N/A GLU 211.A N GLU 123.A O no hydrogen 2.860 N/A ASN 212.A N GLN 217.A O no hydrogen 2.884 N/A ASN 212.A ND2 ASN 121.A OD1 no hydrogen 3.637 N/A THR 213.A N ASN 121.A O no hydrogen 3.317 N/A THR 213.A OG1 ASN 121.A O no hydrogen 3.304 N/A GLN 214.A N ASN 212.A OD1 no hydrogen 2.872 N/A THR 215.A N ASN 212.A OD1 no hydrogen 3.125 N/A GLU 216.A N ASN 212.A O no hydrogen 2.926 N/A LYS 218.A NZ GLU 211.A OE1 no hydrogen 3.341 N/A LEU 219.A N GLN 210.A O no hydrogen 2.812 N/A GLY 221.A N VAL 208.A O no hydrogen 2.955 N/A LYS 222.A N ASN 74.A OD1 no hydrogen 3.287 N/A LEU 223.A N ILE 206.A O no hydrogen 2.670 N/A TYR 224.A N GLY 75.A O no hydrogen 2.703 N/A LEU 225.A N PHE 204.A O no hydrogen 2.712 N/A VAL 226.A N ILE 77.A O no hydrogen 3.032 N/A ASP 227.A N SER 202.A O no hydrogen 2.815 N/A ALA 229.A N HIS 201.A ND1 no hydrogen 2.915 N/A GLU 232.A N ASN 251.A OD1 no hydrogen 3.077 N/A LYS 236.A NZ TYR 303.A O no hydrogen 2.618 N/A LYS 236.A NZ ASN 304.A OD1 no hydrogen 2.866 N/A LYS 236.A NZ GLU 307.A OE2 no hydrogen 2.929 N/A THR 237.A N LYS 233.A O no hydrogen 3.130 N/A THR 237.A OG1 LYS 233.A O no hydrogen 2.878 N/A GLY 238.A N VAL 234.A O no hydrogen 2.842 N/A LEU 244.A N GLY 241.A O no hydrogen 2.973 N/A ASP 245.A N GLY 241.A O no hydrogen 2.980 N/A GLU 246.A N ALA 242.A O no hydrogen 3.037 N/A ALA 247.A N VAL 243.A O no hydrogen 3.144 N/A LYS 248.A N LEU 244.A O no hydrogen 2.785 N/A ASN 249.A N ASP 245.A O no hydrogen 3.425 N/A ASN 249.A ND2 ASP 245.A O no hydrogen 3.212 N/A ILE 250.A N GLU 246.A O no hydrogen 3.128 N/A ASN 251.A N ALA 247.A O no hydrogen 2.963 N/A ASN 251.A ND2 GLU 232.A O no hydrogen 3.265 N/A LYS 252.A N LYS 248.A O no hydrogen 3.251 N/A SER 253.A N ASN 249.A O no hydrogen 3.214 N/A SER 253.A OG HIS 201.A NE2 no hydrogen 2.802 N/A SER 253.A OG ASN 249.A O no hydrogen 3.273 N/A SER 253.A OG ILE 250.A O no hydrogen 2.943 N/A LEU 254.A N ILE 250.A O no hydrogen 2.956 N/A SER 255.A N ASN 251.A O no hydrogen 2.784 N/A SER 255.A OG ASN 251.A O no hydrogen 2.963 N/A SER 255.A OG LYS 252.A O no hydrogen 2.840 N/A ALA 256.A N LYS 252.A O no hydrogen 3.293 N/A LEU 257.A N SER 253.A O no hydrogen 2.884 N/A GLY 258.A N LEU 254.A O no hydrogen 3.102 N/A ASN 259.A N SER 255.A O no hydrogen 2.966 N/A VAL 260.A N ALA 256.A O no hydrogen 3.098 N/A ILE 261.A N LEU 257.A O no hydrogen 3.027 N/A SER 262.A N GLY 258.A O no hydrogen 2.742 N/A SER 262.A OG GLY 258.A O no hydrogen 3.037 N/A ALA 263.A N ASN 259.A O no hydrogen 2.996 N/A LEU 264.A N VAL 260.A O no hydrogen 3.167 N/A ALA 265.A N ILE 261.A O no hydrogen 2.867 N/A GLU 266.A N SER 262.A O no hydrogen 2.855 N/A GLY 267.A N LEU 264.A O no hydrogen 3.346 N/A SER 268.A N ALA 263.A O no hydrogen 2.901 N/A ASP 275.A N PRO 272.A O no hydrogen 3.306 N/A SER 276.A N THR 279.A OG1 no hydrogen 3.006 N/A LYS 277.A NZ ASN 148.A OD1 no hydrogen 3.328 N/A THR 279.A OG1 TYR 273.A O no hydrogen 2.592 N/A THR 279.A OG1 SER 276.A O no hydrogen 2.764 N/A ARG 280.A N LYS 277.A O no hydrogen 2.950 N/A ILE 281.A N LYS 277.A O no hydrogen 3.180 N/A LEU 282.A N MET 278.A O no hydrogen 3.031 N/A GLN 283.A N ARG 280.A O no hydrogen 3.222 N/A SER 285.A OG THR 76.A OG1 no hydrogen 3.046 N/A SER 285.A OG LEU 282.A O no hydrogen 3.446 N/A LEU 286.A N LEU 282.A O no hydrogen 2.899 N/A GLY 287.A N GLN 283.A O no hydrogen 3.158 N/A GLY 288.A N ASP 284.A O no hydrogen 3.095 N/A ASN 289.A ND2 SER 326.A O no hydrogen 2.810 N/A ALA 290.A N GLY 288.A O no hydrogen 2.937 N/A ARG 291.A N ASN 74.A O no hydrogen 2.687 N/A THR 292.A OG1 SER 285.A O no hydrogen 2.700 N/A THR 293.A N THR 76.A O no hydrogen 2.926 N/A ILE 294.A N LYS 6.A O no hydrogen 2.795 N/A VAL 295.A N PHE 78.A O no hydrogen 2.898 N/A ILE 296.A N MET 8.A O no hydrogen 2.885 N/A CYS 297.A N TYR 80.A O no hydrogen 2.797 N/A CYS 298.A N ARG 10.A O no hydrogen 3.034 N/A SER 299.A OG GLU 18.A OE1 no hydrogen 3.479 N/A SER 299.A OG GLU 18.A OE2 no hydrogen 2.544 N/A SER 301.A N SER 299.A OG no hydrogen 3.423 N/A SER 301.A OG ASP 23.A OD2 no hydrogen 2.739 N/A TYR 303.A N SER 301.A OG no hydrogen 2.938 N/A ASN 304.A N SER 301.A O no hydrogen 3.212 N/A GLU 305.A N SER 302.A O no hydrogen 3.404 N/A THR 308.A N ASN 304.A O no hydrogen 2.853 N/A THR 308.A OG1 SER 299.A O no hydrogen 3.246 N/A LYS 309.A N GLU 305.A O no hydrogen 2.847 N/A LYS 309.A NZ GLU 305.A OE2 no hydrogen 2.769 N/A SER 310.A N SER 306.A O no hydrogen 3.075 N/A SER 310.A OG GLU 307.A O no hydrogen 3.296 N/A THR 311.A N GLU 307.A O no hydrogen 3.035 N/A THR 311.A OG1 GLU 307.A O no hydrogen 3.063 N/A LEU 312.A N THR 308.A O no hydrogen 2.969 N/A LEU 313.A N LYS 309.A O no hydrogen 2.859 N/A PHE 314.A N SER 310.A O no hydrogen 3.183 N/A GLY 315.A N THR 311.A O no hydrogen 3.072 N/A GLN 316.A N LEU 312.A O no hydrogen 2.881 N/A GLN 316.A NE2 ALA 43.A O no hydrogen 3.251 N/A ARG 317.A N LEU 313.A O no hydrogen 3.167 N/A ARG 317.A NH2 SER 262.A OG no hydrogen 2.718 N/A ALA 318.A N PHE 314.A O no hydrogen 2.889 N/A LYS 319.A N GLY 315.A O no hydrogen 2.970 N/A THR 320.A N ARG 317.A O no hydrogen 3.060 N/A THR 320.A OG1 ARG 317.A O no hydrogen 2.798 N/A ILE 321.A N ALA 318.A O no hydrogen 3.268 N/A ASN 323.A ND2 SER 285.A O no hydrogen 2.904 N/A THR 324.A N GLY 288.A O no hydrogen 3.327 N/A SER 326.A N ASN 289.A OD1 no hydrogen 2.737 N/A SER 326.A OG ASN 289.A OD1 no hydrogen 2.635 N/A ASN 328.A N GLY 72.A O no hydrogen 2.791 N/A ASN 328.A ND2 ASN 74.A OD1 no hydrogen 2.836 N/A ASN 328.A ND2 SER 220.A O no hydrogen 3.055 N/A