Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4hsq_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 1.A N ASP 24.A OD2 no hydrogen 3.204 N/A GLU 3.A N LYS 22.A O no hydrogen 2.723 N/A LYS 4.A N ASN 135.A OD1 no hydrogen 2.890 N/A LYS 4.A NZ ASP 41.A OD1 no hydrogen 3.568 N/A LYS 4.A NZ ASP 41.A OD2 no hydrogen 2.715 N/A THR 5.A N THR 20.A O no hydrogen 2.822 N/A THR 5.A OG1 THR 20.A O no hydrogen 3.539 N/A LYS 7.A N THR 18.A O no hydrogen 2.872 N/A LYS 7.A NZ ASP 207.A OD1 no hydrogen 3.300 N/A LYS 7.A NZ ASP 207.A OD2 no hydrogen 2.904 N/A ASP 8.A N ASP 207.A OD1 no hydrogen 2.811 N/A ALA 9.A N ASP 207.A OD1 no hydrogen 2.854 N/A GLN 11.A N ASP 8.A O no hydrogen 2.945 N/A GLN 11.A NE2 ALA 9.A O no hydrogen 3.009 N/A ASN 12.A N ASP 15.A OD2 no hydrogen 2.731 N/A ILE 13.A N GLY 199.A O no hydrogen 3.083 N/A GLN 14.A N ARG 104.A O no hydrogen 2.857 N/A ASP 15.A N ASN 12.A O no hydrogen 3.109 N/A TYR 17.A N VAL 102.A O no hydrogen 2.824 N/A TYR 17.A OH TYR 19.A OH no hydrogen 2.915 N/A THR 18.A N LYS 7.A O no hydrogen 3.169 N/A TYR 19.A N PHE 100.A O no hydrogen 3.003 N/A TYR 19.A OH TYR 17.A OH no hydrogen 2.915 N/A THR 20.A N THR 5.A O no hydrogen 2.880 N/A THR 20.A OG1 THR 99.A OG1 no hydrogen 2.788 N/A ILE 21.A N LEU 98.A O no hydrogen 2.784 N/A LYS 22.A N GLU 3.A O no hydrogen 2.729 N/A LYS 22.A NZ SER 97.A OG no hydrogen 2.864 N/A ALA 25.A N ASP 95.A O no hydrogen 2.795 N/A TRP 28.A N SER 93.A OG no hydrogen 3.141 N/A ASP 31.A N ASP 31.A OD1 no hydrogen 2.702 N/A LYS 32.A N GLY 29.A O no hydrogen 3.198 N/A LYS 32.A NZ PRO 124.A O no hydrogen 3.201 N/A ARG 38.A N ILE 120.A O no hydrogen 2.864 N/A ARG 38.A NE GLU 40.A OE2 no hydrogen 2.660 N/A ARG 38.A NH2 GLU 40.A OE2 no hydrogen 3.322 N/A PHE 39.A N VAL 81.A O no hydrogen 2.835 N/A GLU 40.A N ASP 118.A O no hydrogen 2.820 N/A ASP 41.A N LEU 79.A O no hydrogen 2.839 N/A LEU 43.A N ASN 77.A O no hydrogen 2.934 N/A ARG 46.A N ASP 44.A OD2 no hydrogen 2.821 N/A ARG 46.A NE ASP 44.A OD2 no hydrogen 2.899 N/A ARG 46.A NH1 VAL 107.A O no hydrogen 2.783 N/A ARG 46.A NH1 THR 110.A O no hydrogen 2.879 N/A ARG 46.A NH1 THR 110.A OG1 no hydrogen 3.204 N/A ARG 46.A NH1 GLU 112.A O no hydrogen 3.540 N/A ARG 46.A NH2 ASP 44.A OD1 no hydrogen 2.934 N/A ARG 46.A NH2 GLU 112.A O no hydrogen 2.927 N/A LEU 47.A N ASP 44.A O no hydrogen 2.878 N/A ASP 48.A N LYS 103.A O no hydrogen 2.894 N/A GLN 50.A N GLU 101.A O no hydrogen 2.836 N/A LYS 51.A NZ GLU 101.A OE1 no hydrogen 3.062 N/A LYS 51.A NZ GLU 101.A OE2 no hydrogen 3.252 N/A THR 53.A N THR 99.A O no hydrogen 2.785 N/A THR 53.A OG1 THR 99.A O no hydrogen 3.070 N/A GLU 54.A N THR 99.A O no hydrogen 3.131 N/A LYS 56.A N SER 97.A O no hydrogen 2.882 N/A ALA 57.A N THR 60.A O no hydrogen 2.897 N/A GLY 58.A N LYS 96.A O no hydrogen 2.779 N/A THR 60.A N ALA 57.A O no hydrogen 2.897 N/A THR 60.A OG1 ALA 57.A O no hydrogen 3.473 N/A LEU 62.A N VAL 55.A O no hydrogen 2.713 N/A GLY 63.A N ASP 66.A OD2 no hydrogen 2.811 N/A ASP 66.A N GLY 63.A O no hydrogen 2.911 N/A THR 68.A N THR 82.A O no hydrogen 2.705 N/A ASN 70.A N VAL 80.A O no hydrogen 3.190 N/A ASN 70.A ND2 ASP 75.A OD2 no hydrogen 2.882 N/A ASN 70.A ND2 LYS 78.A O no hydrogen 2.876 N/A THR 74.A N ASP 71.A O no hydrogen 3.001 N/A THR 74.A OG1 ASP 71.A O no hydrogen 3.145 N/A ASP 75.A N PRO 72.A O no hydrogen 2.896 N/A ASN 77.A N PRO 72.A O no hydrogen 2.704 N/A ASN 77.A ND2 LEU 43.A O no hydrogen 3.487 N/A ASN 77.A ND2 ASP 44.A O no hydrogen 2.916 N/A ASN 77.A ND2 LEU 47.A O no hydrogen 2.879 N/A LYS 78.A N ASP 75.A O no hydrogen 3.048 N/A LYS 78.A NZ GLU 40.A OE1 no hydrogen 2.964 N/A LEU 79.A N ASP 41.A O no hydrogen 2.703 N/A VAL 80.A N ASN 70.A OD1 no hydrogen 2.846 N/A VAL 81.A N PHE 39.A O no hydrogen 2.926 N/A THR 82.A N THR 68.A O no hydrogen 2.975 N/A LEU 83.A N PHE 37.A O no hydrogen 2.958 N/A THR 84.A N ASP 66.A O no hydrogen 2.949 N/A THR 84.A OG1 SER 65.A O no hydrogen 2.693 N/A GLY 87.A N THR 84.A OG1 no hydrogen 3.188 N/A LEU 88.A N THR 84.A O no hydrogen 2.860 N/A LYS 89.A N ASP 85.A O no hydrogen 3.222 N/A LYS 89.A NZ ASP 85.A O no hydrogen 3.473 N/A LYS 90.A N GLY 87.A O no hydrogen 3.102 N/A LYS 90.A NZ ASP 66.A OD1 no hydrogen 3.413 N/A LYS 90.A NZ ASP 66.A OD2 no hydrogen 2.652 N/A VAL 91.A N LEU 88.A O no hydrogen 3.152 N/A LYS 92.A N ASP 95.A OD2 no hydrogen 2.845 N/A GLY 94.A N PRO 26.A O no hydrogen 2.793 N/A ASP 95.A N LYS 92.A O no hydrogen 2.981 N/A LYS 96.A NZ ASP 24.A OD1 no hydrogen 3.262 N/A LEU 98.A N ILE 21.A O no hydrogen 2.818 N/A THR 99.A N GLU 54.A O no hydrogen 2.794 N/A THR 99.A OG1 THR 20.A OG1 no hydrogen 2.788 N/A PHE 100.A N TYR 19.A O no hydrogen 3.033 N/A GLU 101.A N LYS 51.A O no hydrogen 2.803 N/A VAL 102.A N TYR 17.A O no hydrogen 2.883 N/A LYS 103.A N ASP 48.A O no hydrogen 3.064 N/A ARG 104.A NE GLU 106.A O no hydrogen 3.013 N/A ARG 104.A NH1 THR 111.A O no hydrogen 3.243 N/A ARG 104.A NH1 THR 139.A O no hydrogen 3.303 N/A ARG 104.A NH2 VAL 107.A O no hydrogen 2.966 N/A ARG 104.A NH2 THR 111.A O no hydrogen 2.970 N/A LYS 105.A N ARG 46.A O no hydrogen 2.799 N/A LYS 105.A NZ LYS 45.A O no hydrogen 3.307 N/A VAL 107.A N ASP 198.A OD1 no hydrogen 2.859 N/A THR 110.A OG1 GLU 112.A O no hydrogen 2.789 N/A LEU 113.A N THR 139.A O no hydrogen 2.800 N/A ASN 115.A N VAL 137.A O no hydrogen 2.907 N/A ARG 116.A NH1 THR 134.A O no hydrogen 3.295 N/A ALA 117.A N THR 134.A OG1 no hydrogen 2.954 N/A ASP 118.A N GLU 40.A O no hydrogen 2.931 N/A VAL 119.A N ASN 132.A O no hydrogen 2.850 N/A ILE 120.A N ARG 38.A O no hydrogen 2.923 N/A PHE 121.A N VAL 130.A O no hydrogen 2.983 N/A ASN 122.A N ALA 36.A O no hydrogen 3.155 N/A ASN 122.A ND2 THR 35.A OG1 no hydrogen 3.196 N/A ASN 123.A N LYS 128.A O no hydrogen 2.837 N/A ASN 125.A N ASN 123.A OD1 no hydrogen 3.077 N/A ASN 125.A ND2 THR 27.A O no hydrogen 2.783 N/A ASN 125.A ND2 ASN 123.A OD1 no hydrogen 2.855 N/A THR 126.A N ASN 123.A O no hydrogen 3.301 N/A ASP 127.A N ASN 123.A O no hydrogen 2.680 N/A LYS 128.A N THR 126.A OG1 no hydrogen 3.260 N/A VAL 130.A N PHE 121.A O no hydrogen 2.787 N/A ASN 132.A N VAL 119.A O no hydrogen 2.949 N/A LYS 133.A NZ ASP 118.A OD1 no hydrogen 3.328 N/A THR 134.A N ALA 117.A O no hydrogen 2.848 N/A THR 134.A OG1 ALA 117.A O no hydrogen 3.320 N/A THR 134.A OG1 ASN 135.A O no hydrogen 2.735 N/A ASN 135.A ND2 LYS 4.A O no hydrogen 3.031 N/A VAL 137.A N ASN 115.A O no hydrogen 2.921 N/A THR 139.A N LEU 113.A O no hydrogen 2.907 N/A THR 139.A OG1 ASP 8.A OD2 no hydrogen 2.770 N/A HIS 141.A N THR 111.A O no hydrogen 3.088 N/A HIS 141.A NE2 GLN 11.A O no hydrogen 2.758 N/A GLY 142.A N LEU 200.A O no hydrogen 2.876 N/A LYS 143.A N VAL 258.A O no hydrogen 2.711 N/A LEU 144.A N ILE 197.A O no hydrogen 2.957 N/A LYS 145.A N LEU 260.A O no hydrogen 2.850 N/A LYS 145.A NZ GLU 253.A O no hydrogen 3.202 N/A VAL 146.A N PHE 195.A O no hydrogen 2.938 N/A VAL 147.A N SER 262.A O no hydrogen 2.888 N/A LYS 148.A N GLY 193.A O no hydrogen 2.676 N/A LYS 149.A N ILE 264.A O no hydrogen 2.920 N/A LYS 149.A NZ GLU 263.A OE2 no hydrogen 2.682 N/A ASP 150.A N LYS 156.A O no hydrogen 3.027 N/A GLY 151.A N ASN 266.A O no hydrogen 2.832 N/A LYS 152.A N ASP 150.A OD2 no hydrogen 2.937 N/A LYS 156.A N GLU 153.A O no hydrogen 3.336 N/A LYS 156.A NZ TYR 229.A OH no hydrogen 2.783 N/A LEU 158.A N LYS 148.A O no hydrogen 2.794 N/A LYS 159.A NZ ASP 191.A OD1 no hydrogen 3.225 N/A GLY 160.A N THR 189.A O no hydrogen 2.963 N/A ALA 161.A N THR 189.A OG1 no hydrogen 3.037 N/A GLU 162.A N LYS 224.A O no hydrogen 2.826 N/A PHE 163.A N TRP 187.A O no hydrogen 2.898 N/A GLU 164.A N LYS 221.A O no hydrogen 2.917 N/A TYR 166.A N CYS 219.A O no hydrogen 2.890 N/A TYR 166.A OH GLU 164.A OE1 no hydrogen 2.929 N/A GLN 167.A N LYS 176.A O no hydrogen 2.831 N/A CYS 168.A N LYS 217.A O no hydrogen 2.989 N/A THR 169.A N VAL 173.A O no hydrogen 3.355 N/A ALA 171.A N GLU 238.A OE1 no hydrogen 3.056 N/A ALA 172.A N SER 170.A OG no hydrogen 3.075 N/A VAL 173.A N SER 170.A O no hydrogen 3.112 N/A GLY 175.A N GLN 167.A O no hydrogen 2.720 N/A LEU 179.A N LEU 165.A O no hydrogen 2.764 N/A VAL 181.A N VAL 184.A O no hydrogen 2.836 N/A VAL 184.A N VAL 181.A O no hydrogen 3.191 N/A TRP 187.A N PHE 163.A O no hydrogen 2.960 N/A THR 189.A N ALA 161.A O no hydrogen 2.932 N/A THR 189.A OG1 LEU 158.A O no hydrogen 2.644 N/A GLY 190.A N THR 194.A O no hydrogen 2.857 N/A GLY 193.A N GLY 190.A O no hydrogen 2.916 N/A THR 194.A N ASP 192.A OD1 no hydrogen 3.082 N/A THR 194.A OG1 ASP 192.A OD1 no hydrogen 2.816 N/A THR 194.A OG1 ASP 192.A OD2 no hydrogen 3.185 N/A PHE 195.A N VAL 146.A O no hydrogen 3.261 N/A ILE 197.A N LEU 144.A O no hydrogen 2.756 N/A LEU 200.A N GLY 142.A O no hydrogen 2.822 N/A HIS 201.A N ASN 12.A OD1 no hydrogen 2.766 N/A HIS 201.A ND1 VAL 202.A O no hydrogen 2.697 N/A HIS 201.A NE2 ASP 8.A OD1 no hydrogen 2.753 N/A VAL 202.A N TYR 140.A O no hydrogen 3.109 N/A THR 203.A N PHE 241.A O no hydrogen 2.946 N/A THR 203.A OG1 PHE 241.A O no hydrogen 3.357 N/A GLU 206.A N LYS 209.A O no hydrogen 2.963 N/A ASP 207.A N ASP 8.A OD1 no hydrogen 2.748 N/A LYS 209.A N GLU 206.A O no hydrogen 3.194 N/A ALA 211.A N ASP 204.A O no hydrogen 2.944 N/A LYS 216.A NZ ASP 10.A OD1 no hydrogen 2.782 N/A LYS 216.A NZ ASP 10.A OD2 no hydrogen 3.466 N/A LYS 216.A NZ GLU 206.A OE1 no hydrogen 2.941 N/A LYS 217.A N CYS 168.A O no hydrogen 3.035 N/A LYS 217.A NZ GLU 238.A OE2 no hydrogen 3.000 N/A LYS 217.A NZ GLU 240.A OE1 no hydrogen 3.242 N/A PHE 218.A N ILE 239.A O no hydrogen 3.329 N/A CYS 219.A N TYR 166.A O no hydrogen 2.803 N/A CYS 219.A SG SER 170.A O no hydrogen 3.617 N/A LEU 220.A N THR 237.A O no hydrogen 2.793 N/A LYS 221.A N GLU 164.A O no hydrogen 2.930 N/A GLU 222.A N ASN 235.A O no hydrogen 2.761 N/A THR 223.A N GLU 162.A O no hydrogen 2.786 N/A THR 223.A OG1 GLU 162.A O no hydrogen 3.285 N/A LYS 224.A N GLU 162.A O no hydrogen 3.355 N/A LYS 224.A NZ GLY 160.A O no hydrogen 3.262 N/A LYS 224.A NZ ALA 225.A O no hydrogen 3.220 N/A TYR 229.A N PRO 226.A O no hydrogen 2.960 N/A TYR 229.A OH ASP 150.A OD1 no hydrogen 2.596 N/A ALA 230.A N ILE 267.A O no hydrogen 3.018 N/A ASN 235.A ND2 GLU 222.A O no hydrogen 2.756 N/A THR 237.A N LEU 220.A O no hydrogen 2.855 N/A ILE 239.A N PHE 218.A O no hydrogen 2.743 N/A ARG 243.A N ASP 204.A OD1 no hydrogen 2.965 N/A ARG 243.A NE ASP 204.A OD2 no hydrogen 2.996 N/A ARG 243.A NH1 TYR 140.A OH no hydrogen 3.379 N/A ARG 243.A NH2 ASP 204.A OD2 no hydrogen 3.506 N/A ARG 243.A NH2 GLU 210.A OE2 no hydrogen 2.807 N/A LYS 245.A N THR 242.A OG1 no hydrogen 3.173 N/A LYS 245.A NZ GLU 240.A OE2 no hydrogen 2.829 N/A ILE 246.A N THR 242.A O no hydrogen 2.951 N/A SER 247.A N ARG 243.A O no hydrogen 2.943 N/A ASP 250.A N ASP 255.A O no hydrogen 2.932 N/A LYS 251.A N ASP 255.A OD2 no hydrogen 3.033 N/A ASP 255.A N PHE 252.A O no hydrogen 3.049 N/A GLU 257.A N GLU 257.A OE1 no hydrogen 2.748 N/A VAL 258.A N ASP 256.A OD1 no hydrogen 2.989 N/A THR 259.A N ASP 256.A O no hydrogen 3.492 N/A THR 259.A OG1 ASP 256.A OD1 no hydrogen 2.798 N/A LEU 260.A N LYS 143.A O no hydrogen 2.867 N/A SER 262.A N LYS 145.A O no hydrogen 2.808 N/A ILE 264.A N VAL 147.A O no hydrogen 2.935 N/A ASN 266.A N LYS 149.A O no hydrogen 2.916 N/A LYS 268.A NZ ASP 150.A OD1 no hydrogen 2.650 N/A LYS 268.A NZ GLU 153.A OE1 no hydrogen 3.252 N/A GLN 269.A N GLY 228.A O no hydrogen 2.609 N/A