Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4hvg_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 4.A N VAL 76.A O no hydrogen 3.092 N/A ARG 7.A NE GLU 5.A OE1 no hydrogen 3.415 N/A HIS 8.A N GLU 5.A O no hydrogen 3.052 N/A LEU 9.A N GLU 6.A O no hydrogen 3.006 N/A LYS 10.A N ARG 27.A O no hydrogen 2.629 N/A LYS 10.A NZ ASP 29.A O no hydrogen 3.536 N/A TYR 11.A OH GLN 14.A OE1 no hydrogen 2.781 N/A ILE 12.A N LEU 25.A O no hydrogen 2.884 N/A SER 13.A N LEU 25.A O no hydrogen 3.369 N/A LEU 15.A N VAL 23.A O no hydrogen 3.130 N/A GLY 16.A N VAL 23.A O no hydrogen 3.267 N/A GLY 21.A N GLY 18.A O no hydrogen 2.700 N/A SER 22.A N GLN 43.A O no hydrogen 2.917 N/A VAL 23.A N GLY 16.A O no hydrogen 3.059 N/A GLU 24.A N VAL 41.A O no hydrogen 2.699 N/A LEU 25.A N SER 13.A O no hydrogen 3.183 N/A CYS 26.A N VAL 39.A O no hydrogen 2.903 N/A ARG 27.A N LYS 10.A O no hydrogen 2.715 N/A ARG 27.A NH1 GLY 36.A O no hydrogen 2.909 N/A TYR 28.A N ALA 37.A O no hydrogen 2.817 N/A ASP 29.A N HIS 8.A O no hydrogen 2.760 N/A ASN 34.A N ASP 29.A OD1 no hydrogen 2.626 N/A THR 35.A N ASP 33.A OD1 no hydrogen 2.954 N/A THR 35.A OG1 ASP 33.A OD1 no hydrogen 2.604 N/A THR 35.A OG1 ASP 33.A OD2 no hydrogen 3.398 N/A VAL 39.A N CYS 26.A O no hydrogen 2.899 N/A ALA 40.A N MET 85.A O no hydrogen 2.995 N/A VAL 41.A N GLU 24.A O no hydrogen 2.764 N/A LYS 42.A N LEU 83.A O no hydrogen 2.778 N/A LYS 42.A NZ GLU 58.A OE1 no hydrogen 2.981 N/A LYS 42.A NZ GLU 58.A OE2 no hydrogen 2.801 N/A GLN 43.A N SER 22.A O no hydrogen 2.982 N/A GLN 43.A NE2 SER 22.A O no hydrogen 3.247 N/A GLN 43.A NE2 SER 22.A OG no hydrogen 3.361 N/A GLN 43.A NE2 VAL 41.A O no hydrogen 2.931 N/A GLN 45.A N PHE 20.A O no hydrogen 2.585 N/A GLY 48.A N HIS 46.A NE2 no hydrogen 2.891 N/A ARG 53.A N PRO 49.A O no hydrogen 3.074 N/A ARG 53.A NH2 ASP 54.A OD2 no hydrogen 2.755 N/A ASP 54.A N ASP 50.A O no hydrogen 3.205 N/A PHE 55.A N GLN 51.A O no hydrogen 3.172 N/A GLN 56.A N GLN 52.A O no hydrogen 3.125 N/A ARG 57.A N ARG 53.A O no hydrogen 3.087 N/A GLU 58.A N ASP 54.A O no hydrogen 3.032 N/A ILE 59.A N PHE 55.A O no hydrogen 3.086 N/A GLN 60.A N GLN 56.A O no hydrogen 2.935 N/A ILE 61.A N ARG 57.A O no hydrogen 2.674 N/A LEU 62.A N GLU 58.A O no hydrogen 3.000 N/A LYS 63.A N ILE 59.A O no hydrogen 2.793 N/A ALA 64.A N GLN 60.A O no hydrogen 3.272 N/A ALA 64.A N ILE 61.A O no hydrogen 3.108 N/A LEU 65.A N LEU 62.A O no hydrogen 3.255 N/A HIS 66.A N TYR 122.A OH no hydrogen 2.865 N/A PHE 69.A N SER 67.A OG no hydrogen 3.044 N/A ILE 70.A N SER 67.A O no hydrogen 3.035 N/A VAL 71.A N ILE 148.A O no hydrogen 2.936 N/A LYS 72.A N GLU 86.A OE2 no hydrogen 3.173 N/A ARG 74.A N VAL 84.A O no hydrogen 3.056 N/A GLY 75.A N VAL 84.A O no hydrogen 3.286 N/A VAL 76.A N THR 2.A O no hydrogen 3.159 N/A SER 77.A N ARG 82.A O no hydrogen 3.000 N/A ARG 82.A N SER 77.A O no hydrogen 2.918 N/A LEU 83.A N LYS 42.A O no hydrogen 2.796 N/A VAL 84.A N GLY 75.A O no hydrogen 2.907 N/A MET 85.A N ALA 40.A O no hydrogen 2.758 N/A GLU 86.A N LYS 72.A O no hydrogen 2.934 N/A GLY 91.A N LEU 88.A O no hydrogen 2.859 N/A CYS 92.A SG ARG 136.A O no hydrogen 3.480 N/A LEU 93.A N ILE 138.A O no hydrogen 2.900 N/A ARG 94.A NH1 ASP 95.A OD1 no hydrogen 3.513 N/A PHE 96.A N CYS 92.A O no hydrogen 2.931 N/A LEU 97.A N LEU 93.A O no hydrogen 2.742 N/A GLN 98.A NE2 ARG 94.A O no hydrogen 3.018 N/A ARG 99.A N ASP 95.A O no hydrogen 2.941 N/A HIS 100.A N PHE 96.A O no hydrogen 2.980 N/A ARG 101.A N LEU 97.A O no hydrogen 3.168 N/A ARG 103.A N HIS 100.A O no hydrogen 2.721 N/A LEU 104.A N ARG 101.A O no hydrogen 3.201 N/A SER 107.A OG ASP 105.A OD1 no hydrogen 3.411 N/A SER 107.A OG ASP 105.A OD2 no hydrogen 3.338 N/A ARG 108.A N ASP 105.A OD2 no hydrogen 3.444 N/A ARG 108.A NH1 GLU 143.A O no hydrogen 3.321 N/A LEU 109.A N ASP 105.A O no hydrogen 3.387 N/A LEU 110.A N ALA 106.A O no hydrogen 2.883 N/A LEU 111.A N SER 107.A O no hydrogen 2.578 N/A TYR 112.A N ARG 108.A O no hydrogen 2.727 N/A TYR 112.A OH GLU 143.A O no hydrogen 2.555 N/A SER 113.A N LEU 109.A O no hydrogen 2.803 N/A SER 113.A OG LEU 109.A O no hydrogen 2.637 N/A SER 114.A N LEU 110.A O no hydrogen 2.759 N/A SER 114.A OG ASP 274.A OD1 no hydrogen 2.758 N/A GLN 115.A N LEU 111.A O no hydrogen 3.076 N/A GLN 115.A NE2 ALA 144.A O no hydrogen 3.206 N/A ILE 116.A N TYR 112.A O no hydrogen 2.820 N/A CYS 117.A N SER 113.A O no hydrogen 2.934 N/A CYS 117.A SG PHE 266.A O no hydrogen 3.028 N/A LYS 118.A N SER 114.A O no hydrogen 2.832 N/A LYS 118.A NZ GLU 121.A OE2 no hydrogen 2.714 N/A GLY 119.A N GLN 115.A O no hydrogen 3.072 N/A MET 120.A N ILE 116.A O no hydrogen 2.854 N/A GLU 121.A N CYS 117.A O no hydrogen 2.645 N/A TYR 122.A N LYS 118.A O no hydrogen 3.157 N/A LEU 123.A N GLY 119.A O no hydrogen 2.914 N/A GLY 124.A N MET 120.A O no hydrogen 2.873 N/A SER 125.A N GLU 121.A O no hydrogen 3.018 N/A SER 125.A OG TYR 122.A O no hydrogen 2.614 N/A ARG 126.A N TYR 122.A O no hydrogen 3.064 N/A ARG 126.A N LEU 123.A O no hydrogen 3.080 N/A ARG 127.A N GLY 124.A O no hydrogen 2.997 N/A ARG 127.A NH1 LEU 157.A O no hydrogen 3.033 N/A ARG 127.A NH1 LYS 161.A O no hydrogen 3.301 N/A ARG 127.A NH2 ASP 162.A OD1 no hydrogen 3.085 N/A CYS 128.A N LEU 123.A O no hydrogen 2.965 N/A CYS 128.A SG VAL 129.A O no hydrogen 3.806 N/A CYS 128.A SG LYS 155.A O no hydrogen 3.932 N/A VAL 129.A N LYS 155.A O no hydrogen 2.973 N/A HIS 130.A N ASP 192.A OD1 no hydrogen 2.843 N/A HIS 130.A NE2 ALA 149.A O no hydrogen 2.810 N/A ARG 131.A N ASP 192.A OD2 no hydrogen 3.074 N/A ASP 132.A N HIS 130.A ND1 no hydrogen 3.175 N/A ALA 135.A N GLU 202.A OE2 no hydrogen 2.812 N/A ASN 137.A N ALA 134.A O no hydrogen 2.796 N/A ASN 137.A ND2 ASP 132.A O no hydrogen 2.511 N/A ASN 137.A ND2 ASP 132.A OD2 no hydrogen 2.687 N/A ILE 138.A N ALA 135.A O no hydrogen 3.234 N/A LEU 139.A N LYS 147.A O no hydrogen 2.740 N/A VAL 140.A N GLY 91.A O no hydrogen 3.033 N/A GLU 141.A N HIS 145.A O no hydrogen 2.851 N/A SER 142.A N HIS 145.A O no hydrogen 3.149 N/A HIS 145.A N SER 142.A O no hydrogen 3.091 N/A HIS 145.A NE2 ASP 68.A O no hydrogen 2.619 N/A VAL 146.A N GLN 115.A OE1 no hydrogen 2.886 N/A LYS 147.A N LEU 139.A O no hydrogen 2.838 N/A LYS 147.A NZ GLU 86.A OE2 no hydrogen 2.686 N/A ILE 148.A N PHE 69.A O no hydrogen 2.897 N/A ALA 149.A N ASN 137.A O no hydrogen 2.892 N/A GLY 152.A N ASP 150.A OD2 no hydrogen 3.079 N/A ALA 154.A N PHE 151.A O no hydrogen 3.127 N/A LYS 155.A N VAL 129.A O no hydrogen 2.972 N/A LEU 157.A N ARG 127.A O no hydrogen 2.782 N/A LYS 161.A N PRO 158.A O no hydrogen 3.273 N/A LYS 161.A NZ TYR 163.A OH no hydrogen 3.497 N/A TYR 164.A N PHE 187.A O no hydrogen 2.723 N/A VAL 166.A N ASN 185.A O no hydrogen 2.881 N/A GLU 168.A N GLU 168.A OE1 no hydrogen 2.548 N/A SER 172.A N TYR 177.A OH no hydrogen 3.341 N/A SER 172.A OG ASP 132.A OD1 no hydrogen 3.093 N/A TRP 176.A N PRO 173.A O no hydrogen 3.473 N/A TRP 176.A NE1 GLU 202.A OE2 no hydrogen 2.766 N/A TYR 177.A N ILE 174.A O no hydrogen 3.104 N/A GLU 180.A N GLU 180.A OE2 no hydrogen 2.778 N/A SER 181.A OG ILE 186.A O no hydrogen 2.842 N/A LEU 182.A N ALA 178.A O no hydrogen 3.057 N/A SER 183.A N PRO 179.A O no hydrogen 2.929 N/A SER 183.A OG PRO 179.A O no hydrogen 2.671 N/A SER 183.A OG ASP 184.A OD2 no hydrogen 2.850 N/A ASP 184.A N GLU 180.A O no hydrogen 2.808 N/A ASN 185.A N SER 181.A O no hydrogen 2.946 N/A ASN 185.A ND2 SER 181.A O no hydrogen 3.606 N/A ILE 186.A N GLU 180.A O no hydrogen 3.405 N/A PHE 187.A N TYR 164.A O no hydrogen 2.833 N/A SER 188.A N SER 191.A OG no hydrogen 2.497 N/A ARG 189.A NH1 GLY 124.A O no hydrogen 3.071 N/A GLN 190.A N SER 188.A OG no hydrogen 2.940 N/A SER 191.A N SER 188.A OG no hydrogen 3.276 N/A SER 191.A OG SER 188.A O no hydrogen 2.858 N/A ASP 192.A N SER 188.A O no hydrogen 2.912 N/A VAL 193.A N ARG 189.A O no hydrogen 3.272 N/A TRP 194.A N GLN 190.A O no hydrogen 3.107 N/A SER 195.A N SER 191.A O no hydrogen 3.195 N/A SER 195.A OG TRP 176.A O no hydrogen 2.594 N/A SER 195.A OG SER 191.A O no hydrogen 3.401 N/A PHE 196.A N ASP 192.A O no hydrogen 2.937 N/A GLY 197.A N VAL 193.A O no hydrogen 3.061 N/A VAL 199.A N SER 195.A O no hydrogen 2.881 N/A LEU 200.A N PHE 196.A O no hydrogen 2.975 N/A TYR 201.A N GLY 197.A O no hydrogen 3.089 N/A TYR 201.A OH CYS 211.A O no hydrogen 2.639 N/A GLU 202.A N VAL 198.A O no hydrogen 2.982 N/A LEU 203.A N VAL 199.A O no hydrogen 2.759 N/A PHE 204.A N LEU 200.A O no hydrogen 2.927 N/A THR 205.A N GLU 202.A O no hydrogen 3.363 N/A THR 205.A OG1 TYR 201.A O no hydrogen 2.637 N/A THR 205.A OG1 GLU 202.A O no hydrogen 3.342 N/A TYR 206.A N LEU 203.A O no hydrogen 2.902 N/A TYR 206.A OH LEU 104.A O no hydrogen 2.494 N/A CYS 207.A N GLU 202.A O no hydrogen 2.786 N/A CYS 207.A SG GLU 202.A O no hydrogen 3.878 N/A CYS 207.A SG GLU 202.A OE1 no hydrogen 3.917 N/A ASP 208.A N THR 205.A O no hydrogen 2.898 N/A SER 210.A OG ASP 208.A OD2 no hydrogen 2.538 N/A SER 212.A N LYS 209.A O no hydrogen 3.150 N/A SER 212.A OG LYS 209.A O no hydrogen 2.776 N/A SER 212.A OG SER 214.A OG no hydrogen 2.929 N/A SER 214.A OG SER 212.A OG no hydrogen 2.929 N/A ALA 215.A N SER 212.A OG no hydrogen 2.970 N/A GLU 216.A N SER 212.A O no hydrogen 2.869 N/A PHE 217.A N PRO 213.A O no hydrogen 3.157 N/A LEU 218.A N SER 214.A O no hydrogen 3.142 N/A ARG 219.A N ALA 215.A O no hydrogen 3.010 N/A ARG 219.A NH1 GLU 216.A OE2 no hydrogen 2.465 N/A MET 220.A N GLU 216.A O no hydrogen 2.701 N/A MET 221.A N LEU 218.A O no hydrogen 2.786 N/A ARG 227.A N PRO 223.A O no hydrogen 3.060 N/A ARG 227.A NE VAL 222.A O no hydrogen 3.141 N/A ARG 227.A NH2 VAL 222.A O no hydrogen 3.266 N/A LEU 228.A N ALA 224.A O no hydrogen 2.883 N/A LEU 229.A N LEU 225.A O no hydrogen 3.050 N/A GLU 230.A N SER 226.A O no hydrogen 2.912 N/A LEU 231.A N ARG 227.A O no hydrogen 2.993 N/A LEU 232.A N LEU 228.A O no hydrogen 3.023 N/A GLU 233.A N LEU 229.A O no hydrogen 3.103 N/A GLU 233.A N GLU 230.A O no hydrogen 3.018 N/A GLU 234.A N GLU 230.A O no hydrogen 2.798 N/A GLN 236.A N LEU 231.A O no hydrogen 3.012 N/A GLN 236.A NE2 GLU 234.A OE2 no hydrogen 3.172 N/A ARG 237.A NE TRP 256.A O no hydrogen 3.291 N/A ARG 237.A NH1 TRP 256.A O no hydrogen 2.997 N/A ARG 237.A NH2 LEU 232.A O no hydrogen 2.976 N/A ARG 237.A NH2 GLN 236.A O no hydrogen 2.779 N/A CYS 244.A N PRO 241.A O no hydrogen 3.010 N/A CYS 244.A SG PRO 245.A O no hydrogen 3.193 N/A GLU 247.A N GLU 247.A OE1 no hydrogen 2.745 N/A VAL 248.A N PRO 245.A O no hydrogen 3.218 N/A GLU 250.A N ALA 246.A O no hydrogen 3.015 N/A LEU 251.A N GLU 247.A O no hydrogen 3.302 N/A MET 252.A N VAL 248.A O no hydrogen 3.015 N/A LYS 253.A N HIS 249.A O no hydrogen 2.769 N/A LYS 253.A NZ GLU 250.A OE1 no hydrogen 3.161 N/A LEU 254.A N GLU 250.A O no hydrogen 2.804 N/A CYS 255.A N LEU 251.A O no hydrogen 2.903 N/A CYS 255.A SG LEU 251.A O no hydrogen 3.236 N/A TRP 256.A N MET 252.A O no hydrogen 2.987 N/A TRP 256.A N LYS 253.A O no hydrogen 3.117 N/A TRP 256.A NE1 TRP 194.A O no hydrogen 3.080 N/A ALA 257.A N LEU 254.A O no hydrogen 3.155 N/A ASP 262.A N SER 259.A O no hydrogen 3.059 N/A ARG 263.A N PRO 260.A O no hydrogen 3.052 N/A ARG 263.A NE ALA 257.A O no hydrogen 2.887 N/A ARG 263.A NH1 GLU 180.A OE2 no hydrogen 2.861 N/A ARG 263.A NH1 ALA 257.A O no hydrogen 3.378 N/A ARG 263.A NH2 GLU 180.A OE1 no hydrogen 2.672 N/A ARG 263.A NH2 GLU 180.A OE2 no hydrogen 3.450 N/A ARG 263.A NH2 GLN 190.A O no hydrogen 3.175 N/A SER 265.A OG SER 267.A OG no hydrogen 3.146 N/A SER 267.A OG SER 265.A OG no hydrogen 3.146 N/A ALA 268.A N SER 265.A OG no hydrogen 2.860 N/A LEU 269.A N SER 265.A O no hydrogen 2.829 N/A GLY 270.A N PHE 266.A O no hydrogen 2.887 N/A LEU 273.A N LEU 269.A O no hydrogen 3.061 N/A ASP 274.A N GLY 270.A O no hydrogen 2.987 N/A MET 275.A N PRO 271.A O no hydrogen 2.689 N/A LEU 276.A N GLN 272.A O no hydrogen 2.885 N/A TRP 277.A N LEU 273.A O no hydrogen 2.798 N/A SER 278.A N ASP 274.A O no hydrogen 3.119 N/A SER 278.A OG ASP 274.A O no hydrogen 3.425 N/A GLY 279.A N LEU 276.A O no hydrogen 2.760 N/A SER 280.A N LEU 276.A O no hydrogen 3.130 N/A ARG 281.A N SER 280.A OG no hydrogen 2.906 N/A