Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4hwy_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 5.A N ILE 33.A O no hydrogen 3.035 N/A PHE 10.A N SER 7.A OG no hydrogen 3.120 N/A VAL 11.A N SER 7.A O no hydrogen 3.136 N/A ASP 12.A N LYS 8.A O no hydrogen 2.912 N/A ARG 13.A N ALA 9.A O no hydrogen 3.097 N/A ARG 13.A NE SER 243.A OG no hydrogen 3.390 N/A VAL 14.A N PHE 10.A O no hydrogen 3.018 N/A ASN 15.A N VAL 11.A O no hydrogen 2.975 N/A ASN 15.A ND2 ALA 24.A O no hydrogen 2.815 N/A ARG 16.A N ASP 12.A O no hydrogen 2.948 N/A LEU 17.A N ARG 13.A O no hydrogen 2.803 N/A ASN 18.A N VAL 14.A O no hydrogen 2.842 N/A ASN 18.A ND2 ASN 15.A OD1 no hydrogen 3.181 N/A ARG 19.A N ARG 16.A O no hydrogen 3.253 N/A GLY 20.A N ASN 18.A OD1 no hydrogen 2.856 N/A ILE 21.A N ASN 18.A O no hydrogen 3.302 N/A TRP 22.A NE1 HIS 240.A O no hydrogen 3.006 N/A LYS 23.A N SER 236.A O no hydrogen 2.808 N/A ALA 24.A N ASN 15.A OD1 no hydrogen 2.870 N/A LYS 25.A N ALA 233.A O no hydrogen 2.990 N/A LYS 25.A NZ ASP 27.A O no hydrogen 3.562 N/A LYS 25.A NZ ASP 27.A OD1 no hydrogen 2.868 N/A GLN 31.A N GLY 28.A O no hydrogen 3.030 N/A ILE 33.A N MET 30.A O no hydrogen 3.061 N/A THR 34.A N GLU 37.A OE1 no hydrogen 2.998 N/A THR 34.A OG1 GLU 37.A OE1 no hydrogen 2.623 N/A LEU 35.A N ALA 3.A O no hydrogen 2.992 N/A ARG 36.A N GLU 1.A O no hydrogen 3.101 N/A GLU 37.A N THR 34.A OG1 no hydrogen 3.417 N/A ALA 38.A N THR 34.A O no hydrogen 2.918 N/A LYS 39.A N LEU 35.A O no hydrogen 3.010 N/A ARG 40.A N ARG 36.A O no hydrogen 3.095 N/A ARG 40.A NH1 ALA 86.A O no hydrogen 3.376 N/A ARG 40.A NH1 PHE 178.A O no hydrogen 2.710 N/A ARG 40.A NH2 ASN 131.A OD1 no hydrogen 3.055 N/A ARG 40.A NH2 PHE 178.A O no hydrogen 3.199 N/A LEU 41.A N GLU 37.A O no hydrogen 3.349 N/A ASN 42.A N LYS 39.A O no hydrogen 3.247 N/A ASN 42.A ND2 LEU 247.A O no hydrogen 3.360 N/A VAL 44.A N GLY 249.A O no hydrogen 2.917 N/A ILE 45.A N GLY 133.A O no hydrogen 2.875 N/A ARG 51.A N ALA 204.A O no hydrogen 2.973 N/A ARG 51.A NE GLU 214.A OE1 no hydrogen 2.784 N/A ARG 51.A NH1 ARG 52.A O no hydrogen 3.049 N/A ARG 51.A NH1 GLU 57.A OE1 no hydrogen 3.301 N/A ARG 51.A NH1 GLU 57.A OE2 no hydrogen 2.844 N/A ARG 51.A NH2 GLU 57.A OE1 no hydrogen 2.788 N/A ARG 51.A NH2 GLU 214.A OE1 no hydrogen 3.049 N/A THR 54.A N GLU 57.A OE2 no hydrogen 3.006 N/A GLU 56.A N GLU 56.A OE1 no hydrogen 2.551 N/A GLU 57.A N THR 54.A OG1 no hydrogen 3.132 N/A ALA 58.A N THR 54.A O no hydrogen 2.992 N/A ARG 59.A N GLU 55.A O no hydrogen 3.230 N/A ARG 59.A N GLU 56.A O no hydrogen 3.321 N/A ALA 60.A N GLU 57.A O no hydrogen 3.335 N/A PHE 66.A N TRP 257.A O no hydrogen 2.953 N/A SER 68.A N VAL 255.A O no hydrogen 3.008 N/A SER 68.A OG VAL 255.A O no hydrogen 2.798 N/A ALA 71.A N ASP 67.A O no hydrogen 2.988 N/A TRP 72.A N SER 68.A O no hydrogen 2.835 N/A CYS 75.A N TRP 72.A O no hydrogen 3.283 N/A THR 77.A OG1 ASP 101.A OD1 no hydrogen 2.744 N/A ILE 78.A N CYS 75.A O no hydrogen 3.359 N/A GLN 80.A N THR 77.A O no hydrogen 3.120 N/A GLN 84.A N SER 271.A O no hydrogen 2.909 N/A GLN 84.A NE2 LEU 41.A O no hydrogen 2.991 N/A GLN 84.A NE2 CYS 87.A O no hydrogen 2.863 N/A SER 85.A N ASP 83.A OD1 no hydrogen 2.842 N/A SER 85.A OG PRO 158.A O no hydrogen 2.744 N/A CYS 87.A N SER 85.A O no hydrogen 2.821 N/A GLY 88.A N CYS 130.A O no hydrogen 2.871 N/A SER 89.A OG TYR 155.A OH no hydrogen 2.857 N/A CYS 90.A SG LEU 41.A O no hydrogen 3.889 N/A CYS 90.A SG HIS 250.A ND1 no hydrogen 3.133 N/A TRP 91.A NE1 GLY 129.A O no hydrogen 3.118 N/A ALA 92.A N SER 89.A O no hydrogen 2.778 N/A VAL 93.A N SER 89.A O no hydrogen 2.842 N/A ALA 94.A N CYS 90.A O no hydrogen 2.859 N/A ALA 96.A N ALA 92.A O no hydrogen 2.800 N/A SER 97.A N VAL 93.A O no hydrogen 2.931 N/A SER 97.A OG VAL 93.A O no hydrogen 3.061 N/A ALA 98.A N ALA 94.A O no hydrogen 3.174 N/A MET 99.A N ALA 95.A O no hydrogen 2.843 N/A SER 100.A N ALA 96.A O no hydrogen 3.009 N/A SER 100.A OG ALA 96.A O no hydrogen 2.753 N/A ASP 101.A N SER 97.A O no hydrogen 3.083 N/A ARG 102.A N ALA 98.A O no hydrogen 2.834 N/A ARG 102.A NE PRO 220.A O no hydrogen 2.800 N/A ARG 102.A NH1 TYR 203.A OH no hydrogen 3.370 N/A ARG 102.A NH1 GLU 214.A OE2 no hydrogen 3.030 N/A ARG 102.A NH1 GLY 300.A O no hydrogen 2.846 N/A ARG 102.A NH2 GLU 214.A OE2 no hydrogen 2.702 N/A ARG 102.A NH2 GLY 219.A O no hydrogen 2.889 N/A PHE 103.A N MET 99.A O no hydrogen 2.985 N/A PHE 103.A N SER 100.A O no hydrogen 3.171 N/A CYS 104.A N ASP 101.A O no hydrogen 2.993 N/A CYS 104.A SG ASN 74.A O no hydrogen 3.997 N/A CYS 104.A SG GLN 110.A O no hydrogen 3.681 N/A THR 105.A N ASP 101.A O no hydrogen 2.953 N/A THR 105.A OG1 ARG 218.A O no hydrogen 2.763 N/A MET 106.A N ARG 102.A O no hydrogen 2.835 N/A GLY 107.A N ARG 102.A O no hydrogen 3.065 N/A GLY 107.A N PHE 103.A O no hydrogen 2.982 N/A VAL 109.A N PHE 103.A O no hydrogen 2.940 N/A GLN 110.A NE2 ASN 74.A O no hydrogen 2.869 N/A HIS 113.A NE2 GLN 80.A OE1 no hydrogen 2.599 N/A ILE 114.A N SER 100.A OG no hydrogen 2.963 N/A SER 115.A N VAL 148.A O no hydrogen 2.945 N/A SER 115.A OG GLN 153.A O no hydrogen 2.823 N/A ASP 118.A N SER 115.A OG no hydrogen 3.155 N/A LEU 120.A N ALA 116.A O no hydrogen 2.867 N/A ALA 121.A N GLY 117.A O no hydrogen 2.876 N/A CYS 122.A N ASP 118.A O no hydrogen 2.783 N/A CYS 122.A SG ASP 118.A OD1 no hydrogen 3.275 N/A CYS 123.A N LEU 119.A O no hydrogen 3.011 N/A CYS 126.A N CYS 123.A O no hydrogen 3.321 N/A GLY 127.A N SER 124.A O no hydrogen 3.359 N/A ASP 128.A N GLY 132.A O no hydrogen 2.750 N/A CYS 130.A N THR 180.A OG1 no hydrogen 2.978 N/A CYS 130.A SG PHE 178.A O no hydrogen 3.997 N/A ASN 131.A N ASP 128.A O no hydrogen 2.933 N/A ASN 131.A ND2 ASP 128.A O no hydrogen 3.666 N/A ASN 131.A ND2 ASP 128.A OD2 no hydrogen 2.642 N/A GLY 132.A N GLY 129.A O no hydrogen 3.089 N/A GLY 133.A N GLY 43.A O no hydrogen 2.878 N/A ASP 134.A N CYS 126.A O no hydrogen 2.757 N/A ASP 136.A N ASP 134.A OD1 no hydrogen 2.900 N/A ARG 137.A N ASP 134.A O no hydrogen 3.131 N/A ARG 137.A NH1 ASP 125.A OD1 no hydrogen 3.130 N/A ALA 138.A N ASP 134.A O no hydrogen 3.324 N/A TRP 139.A N PRO 135.A O no hydrogen 3.342 N/A TRP 139.A NE1 GLU 222.A OE1 no hydrogen 2.938 N/A ALA 140.A N ASP 136.A O no hydrogen 3.116 N/A TYR 141.A N ARG 137.A O no hydrogen 2.762 N/A PHE 142.A N ALA 138.A O no hydrogen 3.013 N/A SER 143.A N TRP 139.A O no hydrogen 3.239 N/A SER 143.A OG SER 199.A O no hydrogen 3.506 N/A SER 143.A OG SER 199.A OG no hydrogen 2.880 N/A SER 143.A OG SER 202.A OG no hydrogen 3.146 N/A SER 144.A N ALA 140.A O no hydrogen 3.021 N/A SER 144.A OG ALA 140.A O no hydrogen 3.263 N/A SER 144.A OG TYR 141.A O no hydrogen 3.526 N/A THR 145.A N TYR 141.A O no hydrogen 2.798 N/A GLY 146.A N TYR 141.A O no hydrogen 2.982 N/A LEU 147.A N TYR 197.A O no hydrogen 2.783 N/A VAL 148.A N ASP 118.A OD2 no hydrogen 3.043 N/A ASP 150.A N HIS 113.A O no hydrogen 2.741 N/A GLN 153.A N SER 149.A O no hydrogen 2.955 N/A GLN 153.A NE2 ASN 184.A O no hydrogen 3.145 N/A GLN 153.A NE2 THR 186.A O no hydrogen 3.097 N/A TYR 155.A OH GLN 84.A O no hydrogen 2.662 N/A TYR 155.A OH SER 89.A OG no hydrogen 2.857 N/A CYS 160.A N ASP 83.A OD2 no hydrogen 3.239 N/A CYS 160.A SG SER 85.A OG no hydrogen 3.694 N/A SER 161.A N PRO 171.A O no hydrogen 2.815 N/A SER 161.A OG GLU 275.A OE1 no hydrogen 2.456 N/A HIS 163.A N SER 161.A OG no hydrogen 3.220 N/A LYS 165.A N HIS 163.A ND1 no hydrogen 3.151 N/A SER 166.A OG GLU 275.A OE2 no hydrogen 2.628 N/A ASN 168.A N SER 166.A OG no hydrogen 3.096 N/A GLY 169.A N SER 166.A O no hydrogen 2.977 N/A TYR 170.A N SER 166.A OG no hydrogen 3.105 N/A CYS 173.A N SER 161.A O no hydrogen 2.880 N/A GLN 175.A N PRO 172.A O no hydrogen 3.284 N/A PHE 176.A N CYS 173.A O no hydrogen 3.019 N/A PHE 178.A N ALA 86.A O no hydrogen 3.432 N/A THR 180.A OG1 ASP 128.A O no hydrogen 3.559 N/A LYS 182.A NZ CYS 183.A O no hydrogen 3.251 N/A LYS 182.A NZ ASN 184.A OD1 no hydrogen 3.299 N/A CYS 183.A SG TYR 185.A OH no hydrogen 3.701 N/A THR 186.A OG1 CYS 187.A O no hydrogen 3.421 N/A CYS 187.A SG ILE 192.A O no hydrogen 3.115 N/A ASP 188.A N CYS 152.A O no hydrogen 2.945 N/A THR 191.A N ASP 189.A OD1 no hydrogen 2.903 N/A THR 191.A OG1 ASP 189.A OD1 no hydrogen 2.806 N/A THR 191.A OG1 ASP 189.A OD2 no hydrogen 3.548 N/A ILE 192.A N ASP 189.A O no hydrogen 2.964 N/A ASN 196.A ND2 THR 145.A O no hydrogen 3.534 N/A TYR 197.A N LEU 147.A O no hydrogen 2.680 N/A SER 199.A N PHE 142.A O no hydrogen 3.231 N/A SER 199.A OG SER 143.A OG no hydrogen 2.880 N/A TRP 200.A N ILE 301.A O no hydrogen 2.975 N/A SER 202.A OG TRP 139.A O no hydrogen 3.206 N/A SER 202.A OG SER 143.A OG no hydrogen 3.146 N/A TYR 203.A N ALA 299.A O no hydrogen 2.978 N/A TYR 203.A OH GLU 214.A OE1 no hydrogen 3.348 N/A TYR 203.A OH GLU 214.A OE2 no hydrogen 2.458 N/A ALA 204.A N PRO 49.A O no hydrogen 2.844 N/A LEU 205.A N GLY 297.A O no hydrogen 2.999 N/A GLN 206.A N ASP 210.A OD2 no hydrogen 3.002 N/A GLY 207.A N GLU 294.A O no hydrogen 2.979 N/A TYR 211.A N GLY 207.A O no hydrogen 3.268 N/A TYR 211.A OH ILE 293.A O no hydrogen 2.763 N/A MET 212.A N GLU 208.A O no hydrogen 3.014 N/A ARG 213.A N ASP 209.A O no hydrogen 2.897 N/A ARG 213.A NE GLU 57.A O no hydrogen 2.926 N/A ARG 213.A NH1 GLU 57.A O no hydrogen 3.563 N/A ARG 213.A NH2 ASP 209.A OD2 no hydrogen 3.213 N/A GLU 214.A N ASP 210.A O no hydrogen 2.676 N/A LEU 215.A N TYR 211.A O no hydrogen 2.870 N/A PHE 216.A N MET 212.A O no hydrogen 2.932 N/A PHE 217.A N ARG 213.A O no hydrogen 3.156 N/A ARG 218.A N GLU 214.A O no hydrogen 3.023 N/A ARG 218.A NH1 TYR 203.A OH no hydrogen 2.824 N/A GLY 219.A N LEU 215.A O no hydrogen 2.992 N/A GLU 222.A N SER 298.A O no hydrogen 3.287 N/A VAL 223.A N VAL 252.A O no hydrogen 2.938 N/A PHE 225.A N HIS 250.A O no hydrogen 3.161 N/A ASP 226.A N CYS 291.A O no hydrogen 2.838 N/A VAL 227.A N GLY 248.A O no hydrogen 2.908 N/A GLU 229.A N GLN 245.A O no hydrogen 3.016 N/A PHE 231.A N TYR 228.A O no hydrogen 3.160 N/A ILE 232.A N GLU 229.A O no hydrogen 3.273 N/A ALA 233.A N ASP 230.A O no hydrogen 3.182 N/A TYR 234.A N PHE 231.A O no hydrogen 2.901 N/A TYR 234.A OH GLY 237.A O no hydrogen 2.631 N/A ASN 235.A N LYS 23.A O no hydrogen 2.879 N/A SER 236.A N LYS 23.A O no hydrogen 3.450 N/A SER 236.A OG ASN 235.A OD1 no hydrogen 3.331 N/A VAL 238.A N ILE 21.A O no hydrogen 3.190 N/A TYR 239.A N LEU 283.A O no hydrogen 2.996 N/A TYR 239.A OH ASP 230.A OD1 no hydrogen 2.665 N/A HIS 241.A N GLU 290.A OE2 no hydrogen 2.796 N/A VAL 242.A N ASP 230.A OD2 no hydrogen 2.814 N/A SER 243.A N ASP 230.A OD2 no hydrogen 3.085 N/A GLN 245.A N GLU 229.A OE1 no hydrogen 2.699 N/A GLN 245.A NE2 GLU 229.A OE2 no hydrogen 3.147 N/A LEU 247.A N VAL 227.A O no hydrogen 2.618 N/A HIS 250.A N PHE 225.A O no hydrogen 3.014 N/A HIS 250.A NE2 ASN 270.A OD1 no hydrogen 2.850 N/A VAL 252.A N VAL 223.A O no hydrogen 2.863 N/A ARG 253.A N ALA 269.A O no hydrogen 3.387 N/A ARG 253.A NH1 ILE 78.A O no hydrogen 3.552 N/A ARG 253.A NH2 ILE 78.A O no hydrogen 2.844 N/A ARG 253.A NH2 ASP 101.A OD2 no hydrogen 2.771 N/A LEU 254.A N PHE 221.A O no hydrogen 2.894 N/A VAL 255.A N LYS 267.A O no hydrogen 3.105 N/A GLY 256.A N LYS 267.A O no hydrogen 3.283 N/A TRP 257.A N PHE 66.A O no hydrogen 2.862 N/A TRP 257.A NE1 PRO 63.A O no hydrogen 3.059 N/A GLY 258.A N TYR 265.A O no hydrogen 3.248 N/A SER 260.A N VAL 263.A O no hydrogen 2.829 N/A VAL 263.A N SER 260.A O no hydrogen 2.788 N/A TYR 265.A N GLY 258.A O no hydrogen 2.893 N/A TRP 266.A N ILE 284.A O no hydrogen 2.819 N/A TRP 266.A NE1 GLU 294.A OE2 no hydrogen 2.813 N/A LYS 267.A N GLY 256.A O no hydrogen 2.837 N/A LYS 267.A NZ ASP 67.A OD1 no hydrogen 2.905 N/A ILE 268.A N PHE 282.A O no hydrogen 2.938 N/A ALA 269.A N ARG 253.A O no hydrogen 2.898 N/A ASN 270.A N GLY 280.A O no hydrogen 3.026 N/A SER 271.A N ASN 270.A OD1 no hydrogen 2.821 N/A SER 271.A OG GLN 84.A OE1 no hydrogen 2.810 N/A TRP 272.A NE1 GLN 84.A OE1 no hydrogen 3.041 N/A ASN 273.A N ALA 82.A O no hydrogen 3.069 N/A ASN 273.A ND2 ASP 83.A OD2 no hydrogen 3.141 N/A GLU 275.A N ASN 273.A OD1 no hydrogen 2.699 N/A MET 278.A N TYR 281.A O no hydrogen 2.763 N/A GLY 280.A N TRP 276.A O no hydrogen 2.788 N/A TYR 281.A N MET 278.A O no hydrogen 3.033 N/A TYR 281.A OH PRO 79.A O no hydrogen 3.172 N/A PHE 282.A N ILE 268.A O no hydrogen 2.996 N/A LEU 283.A N TYR 234.A OH no hydrogen 3.078 N/A ILE 284.A N TRP 266.A O no hydrogen 3.128 N/A ARG 285.A N TYR 239.A O no hydrogen 3.073 N/A ARG 285.A NH2 GLU 290.A OE1 no hydrogen 3.155 N/A ARG 286.A N PRO 264.A O no hydrogen 3.052 N/A ARG 286.A NE TYR 265.A O no hydrogen 2.957 N/A ARG 286.A NH1 GLU 208.A OE2 no hydrogen 2.735 N/A ARG 286.A NH2 GLY 258.A O no hydrogen 2.769 N/A GLY 287.A N GLU 294.A OE2 no hydrogen 2.854 N/A SER 289.A N GLU 294.A OE1 no hydrogen 2.871 N/A SER 289.A OG ASP 295.A OD1 no hydrogen 2.599 N/A CYS 291.A SG GLU 290.A OE2 no hydrogen 3.903 N/A GLY 292.A N SER 289.A O no hydrogen 2.917 N/A ILE 293.A N GLU 290.A O no hydrogen 2.901 N/A GLU 294.A N SER 289.A OG no hydrogen 3.002 N/A ASP 295.A N GLY 292.A O no hydrogen 2.952 N/A GLY 297.A N LEU 205.A O no hydrogen 2.781 N/A SER 298.A N GLU 222.A O no hydrogen 2.966 N/A SER 298.A OG ASP 136.A OD1 no hydrogen 2.731 N/A ALA 299.A N TYR 203.A O no hydrogen 2.992 N/A ILE 301.A N THR 201.A O no hydrogen 3.044 N/A LEU 303.A N ARG 198.A O no hydrogen 2.880 N/A THR 307.A OG1 ALA 308.A O no hydrogen 3.137 N/A