Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4hx5_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 4.A NH1 GLU 1.A OE1 no hydrogen 3.372 N/A ARG 4.A NH2 GLU 1.A OE1 no hydrogen 3.228 N/A MET 7.A N ARG 4.A O no hydrogen 2.872 N/A LEU 8.A N PRO 5.A O no hydrogen 3.133 N/A GLN 9.A N GLU 6.A O no hydrogen 3.202 N/A GLY 10.A N GLY 34.A O no hydrogen 2.723 N/A LYS 11.A N LEU 8.A O no hydrogen 3.000 N/A LYS 11.A NZ MET 7.A O no hydrogen 3.391 N/A LYS 12.A N ASP 90.A OD2 no hydrogen 2.641 N/A LYS 12.A NZ MET 86.A O no hydrogen 2.835 N/A VAL 13.A N HIS 36.A O no hydrogen 2.836 N/A ILE 14.A N MET 91.A O no hydrogen 2.995 N/A VAL 15.A N VAL 38.A O no hydrogen 3.032 N/A THR 16.A N ILE 93.A O no hydrogen 3.078 N/A THR 16.A OG1 ILE 93.A O no hydrogen 3.563 N/A THR 16.A OG1 HIS 96.A ND1 no hydrogen 2.768 N/A ALA 18.A N THR 40.A O no hydrogen 3.063 N/A ARG 24.A N LYS 20.A O no hydrogen 3.141 N/A GLU 25.A N GLY 21.A O no hydrogen 3.261 N/A MET 26.A N ILE 22.A O no hydrogen 2.899 N/A ALA 27.A N GLY 23.A O no hydrogen 3.010 N/A TYR 28.A N ARG 24.A O no hydrogen 3.019 N/A HIS 29.A N GLU 25.A O no hydrogen 3.038 N/A HIS 29.A NE2 GLU 215.A O no hydrogen 2.794 N/A LEU 30.A N MET 26.A O no hydrogen 2.998 N/A ALA 31.A N ALA 27.A O no hydrogen 2.884 N/A LYS 32.A N TYR 28.A O no hydrogen 2.919 N/A MET 33.A N HIS 29.A O no hydrogen 3.068 N/A GLY 34.A N ALA 31.A O no hydrogen 2.944 N/A ALA 35.A N LEU 30.A O no hydrogen 3.050 N/A HIS 36.A N LYS 11.A O no hydrogen 2.700 N/A HIS 36.A ND1 SER 61.A OG no hydrogen 2.514 N/A VAL 37.A N SER 61.A O no hydrogen 2.958 N/A VAL 38.A N VAL 13.A O no hydrogen 3.015 N/A VAL 39.A N HIS 63.A O no hydrogen 2.924 N/A THR 40.A N VAL 15.A O no hydrogen 3.135 N/A THR 40.A OG1 ILE 65.A O no hydrogen 2.574 N/A LYS 44.A NZ GLU 45.A OE1 no hydrogen 3.258 N/A THR 46.A OG1 SER 43.A O no hydrogen 3.240 N/A LEU 47.A N SER 43.A O no hydrogen 3.099 N/A GLN 48.A N LYS 44.A O no hydrogen 2.813 N/A GLN 48.A NE2 TYR 64.A OH no hydrogen 2.988 N/A VAL 50.A N THR 46.A O no hydrogen 3.172 N/A VAL 51.A N LEU 47.A O no hydrogen 2.855 N/A SER 52.A N GLN 48.A O no hydrogen 2.986 N/A SER 52.A OG LYS 49.A O no hydrogen 3.286 N/A HIS 53.A N LYS 49.A O no hydrogen 3.096 N/A CYS 54.A N VAL 50.A O no hydrogen 2.923 N/A CYS 54.A SG VAL 50.A O no hydrogen 3.201 N/A LEU 55.A N VAL 51.A O no hydrogen 3.135 N/A GLU 56.A N SER 52.A O no hydrogen 3.215 N/A LEU 57.A N HIS 53.A O no hydrogen 3.031 N/A LEU 57.A N CYS 54.A O no hydrogen 3.248 N/A GLY 58.A N LEU 55.A O no hydrogen 3.260 N/A ALA 59.A N CYS 54.A O no hydrogen 3.111 N/A ALA 60.A N ALA 35.A O no hydrogen 3.073 N/A SER 61.A OG HIS 36.A ND1 no hydrogen 2.514 N/A HIS 63.A N VAL 37.A O no hydrogen 3.037 N/A ILE 65.A N VAL 39.A O no hydrogen 3.103 N/A GLY 67.A N ALA 41.A O no hydrogen 3.087 N/A THR 68.A OG1 GLU 70.A OE2 no hydrogen 2.659 N/A GLU 70.A N THR 68.A OG1 no hydrogen 3.148 N/A ASP 71.A N THR 68.A O no hydrogen 3.163 N/A THR 73.A N ASP 71.A OD1 no hydrogen 3.117 N/A PHE 74.A N ASP 71.A OD1 no hydrogen 3.388 N/A ALA 75.A N ASP 71.A O no hydrogen 3.157 N/A GLU 76.A N MET 72.A O no hydrogen 3.106 N/A GLN 77.A N THR 73.A O no hydrogen 2.877 N/A PHE 78.A N PHE 74.A O no hydrogen 2.659 N/A VAL 79.A N ALA 75.A O no hydrogen 3.371 N/A ALA 80.A N GLU 76.A O no hydrogen 3.410 N/A GLN 81.A N GLN 77.A O no hydrogen 2.955 N/A ALA 82.A N PHE 78.A O no hydrogen 2.893 N/A GLY 83.A N VAL 79.A O no hydrogen 2.960 N/A LYS 84.A N ALA 80.A O no hydrogen 2.901 N/A LEU 85.A N GLN 81.A O no hydrogen 2.911 N/A MET 86.A N ALA 82.A O no hydrogen 3.089 N/A GLY 88.A N GLY 83.A O no hydrogen 2.820 N/A ASP 90.A N LYS 12.A O no hydrogen 2.863 N/A MET 91.A N LYS 12.A O no hydrogen 3.151 N/A LEU 92.A N SER 140.A O no hydrogen 2.870 N/A ILE 93.A N ILE 14.A O no hydrogen 2.864 N/A LEU 94.A N VAL 142.A O no hydrogen 2.776 N/A ASN 95.A N THR 16.A OG1 no hydrogen 3.012 N/A HIS 96.A N THR 16.A OG1 no hydrogen 3.275 N/A HIS 96.A ND1 THR 16.A OG1 no hydrogen 2.768 N/A HIS 96.A NE2 SER 122.A OG no hydrogen 2.726 N/A THR 98.A N ASN 119.A OD1 no hydrogen 2.916 N/A THR 100.A OG1 THR 98.A O no hydrogen 2.806 N/A ASN 103.A N MET 155.A O no hydrogen 3.024 N/A HIS 106.A N ASP 108.A OD1 no hydrogen 2.792 N/A ILE 109.A N ASP 107.A O no hydrogen 2.898 N/A HIS 111.A N ASP 108.A O no hydrogen 3.143 N/A VAL 112.A N ASP 108.A O no hydrogen 3.375 N/A ARG 113.A N ILE 109.A O no hydrogen 2.887 N/A LYS 114.A N HIS 110.A O no hydrogen 2.860 N/A LYS 114.A NZ GLU 70.A OE1 no hydrogen 2.911 N/A SER 115.A N HIS 111.A O no hydrogen 2.916 N/A SER 115.A OG HIS 111.A O no hydrogen 2.772 N/A MET 116.A N VAL 112.A O no hydrogen 2.976 N/A GLU 117.A N ARG 113.A O no hydrogen 2.833 N/A VAL 118.A N LYS 114.A O no hydrogen 2.859 N/A ASN 119.A N SER 115.A O no hydrogen 2.886 N/A ASN 119.A ND2 SER 162.A OG no hydrogen 3.074 N/A PHE 120.A N MET 116.A O no hydrogen 3.268 N/A LEU 121.A N MET 116.A O no hydrogen 2.888 N/A SER 122.A N GLU 117.A O no hydrogen 2.923 N/A SER 122.A OG HIS 96.A NE2 no hydrogen 2.726 N/A SER 122.A OG VAL 118.A O no hydrogen 2.606 N/A TYR 123.A N PHE 120.A O no hydrogen 3.114 N/A TYR 123.A OH HIS 96.A O no hydrogen 2.623 N/A VAL 124.A N PHE 120.A O no hydrogen 3.407 N/A VAL 125.A N LEU 121.A O no hydrogen 3.027 N/A LEU 126.A N SER 122.A O no hydrogen 2.853 N/A THR 127.A N TYR 123.A O no hydrogen 2.960 N/A THR 127.A OG1 TYR 123.A O no hydrogen 2.802 N/A VAL 128.A N VAL 124.A O no hydrogen 2.882 N/A ALA 129.A N VAL 125.A O no hydrogen 3.052 N/A ALA 130.A N LEU 126.A O no hydrogen 2.909 N/A LEU 131.A N THR 127.A O no hydrogen 2.815 N/A LEU 134.A N ALA 130.A O no hydrogen 2.993 N/A LYS 135.A N LEU 131.A O no hydrogen 2.802 N/A GLN 136.A N PRO 132.A O no hydrogen 3.233 N/A SER 137.A N MET 133.A O no hydrogen 3.317 N/A SER 137.A OG LEU 89.A O no hydrogen 2.794 N/A SER 137.A OG MET 133.A O no hydrogen 3.513 N/A SER 137.A OG LEU 134.A O no hydrogen 3.450 N/A GLY 139.A N LEU 134.A O no hydrogen 2.733 N/A SER 140.A N ASP 90.A O no hydrogen 2.871 N/A SER 140.A OG SER 185.A OG no hydrogen 2.676 N/A ILE 141.A N SER 185.A O no hydrogen 2.859 N/A VAL 142.A N LEU 92.A O no hydrogen 2.790 N/A VAL 143.A N THR 187.A O no hydrogen 2.709 N/A VAL 144.A N LEU 94.A O no hydrogen 2.897 N/A SER 145.A N CYS 189.A O no hydrogen 2.734 N/A SER 146.A N SER 145.A OG no hydrogen 2.605 N/A LEU 147.A N LEU 191.A O no hydrogen 2.984 N/A ALA 148.A N SER 146.A OG no hydrogen 2.869 N/A GLY 149.A N SER 146.A O no hydrogen 2.755 N/A LYS 150.A N LEU 147.A O no hydrogen 2.955 N/A LYS 150.A NZ ASP 167.A OD2 no hydrogen 2.820 N/A LYS 150.A NZ GLU 231.A OE1 no hydrogen 2.795 N/A LYS 150.A NZ GLU 231.A OE2 no hydrogen 3.498 N/A VAL 151.A N LEU 147.A O no hydrogen 2.983 N/A SER 160.A N VAL 156.A O no hydrogen 2.710 N/A SER 160.A OG ALA 148.A O no hydrogen 2.880 N/A ALA 161.A N ALA 157.A O no hydrogen 2.884 N/A SER 162.A N ALA 158.A O no hydrogen 3.161 N/A SER 162.A OG TYR 159.A O no hydrogen 2.737 N/A LYS 163.A N TYR 159.A O no hydrogen 3.081 N/A LYS 163.A NZ VAL 144.A O no hydrogen 2.878 N/A PHE 164.A N SER 160.A O no hydrogen 2.894 N/A ALA 165.A N ALA 161.A O no hydrogen 2.994 N/A LEU 166.A N SER 162.A O no hydrogen 3.181 N/A ASP 167.A N LYS 163.A O no hydrogen 3.317 N/A GLY 168.A N PHE 164.A O no hydrogen 3.149 N/A PHE 169.A N ALA 165.A O no hydrogen 2.913 N/A PHE 170.A N LEU 166.A O no hydrogen 2.858 N/A SER 171.A N ASP 167.A O no hydrogen 2.839 N/A SER 171.A OG ASP 167.A O no hydrogen 2.894 N/A SER 171.A OG ASP 167.A OD1 no hydrogen 2.650 N/A SER 172.A N.A GLY 168.A O no hydrogen 3.210 N/A SER 172.A N.B GLY 168.A O no hydrogen 3.213 N/A SER 172.A OG.B GLY 168.A O no hydrogen 2.799 N/A ILE 173.A N PHE 169.A O no hydrogen 3.073 N/A ARG 174.A N PHE 170.A O no hydrogen 3.046 N/A ARG 174.A NE ILE 186.A O no hydrogen 3.075 N/A ARG 174.A NH2 ILE 186.A O no hydrogen 2.971 N/A LYS 175.A N SER 171.A O no hydrogen 3.461 N/A LYS 175.A NZ GLU 253.A OE2 no hydrogen 2.770 N/A GLU 176.A N SER 172.A O.A no hydrogen 3.216 N/A GLU 176.A N SER 172.A O.B no hydrogen 3.253 N/A TYR 177.A N ILE 173.A O no hydrogen 2.761 N/A SER 178.A N ARG 174.A O no hydrogen 2.976 N/A SER 178.A OG LYS 175.A O no hydrogen 3.551 N/A VAL 179.A N LYS 175.A O no hydrogen 3.226 N/A SER 180.A N GLU 176.A O no hydrogen 3.015 N/A SER 180.A OG GLU 176.A O no hydrogen 2.659 N/A VAL 182.A N TYR 177.A O no hydrogen 2.825 N/A SER 185.A N GLY 139.A O no hydrogen 3.182 N/A THR 187.A N ILE 141.A O no hydrogen 2.850 N/A THR 187.A OG1 GLN 229.A O no hydrogen 2.647 N/A LEU 188.A N GLU 230.A O no hydrogen 2.841 N/A CYS 189.A N VAL 143.A O no hydrogen 2.814 N/A CYS 189.A SG VAL 143.A O no hydrogen 3.814 N/A VAL 190.A N VAL 232.A O no hydrogen 2.695 N/A GLY 192.A N TYR 234.A O no hydrogen 2.750 N/A ASP 195.A N ALA 212.A O no hydrogen 2.929 N/A THR 196.A N ILE 194.A O no hydrogen 2.832 N/A ALA 199.A N THR 196.A OG1 no hydrogen 3.136 N/A MET 200.A N THR 196.A O no hydrogen 2.961 N/A LYS 201.A N GLU 197.A O no hydrogen 3.058 N/A LYS 201.A NZ GLU 197.A OE1 no hydrogen 3.430 N/A ALA 202.A N THR 198.A O no hydrogen 3.013 N/A VAL 203.A N ALA 199.A O no hydrogen 2.939 N/A SER 204.A N MET 200.A O no hydrogen 3.197 N/A SER 204.A OG MET 200.A O no hydrogen 2.817 N/A ILE 206.A N VAL 203.A O no hydrogen 2.790 N/A VAL 207.A N VAL 203.A O no hydrogen 3.074 N/A ALA 212.A N LEU 193.A O no hydrogen 2.892 N/A LYS 214.A N ASP 195.A OD2 no hydrogen 2.930 N/A GLU 215.A N GLU 215.A OE2 no hydrogen 2.859 N/A CYS 217.A N PRO 213.A O no hydrogen 3.018 N/A ALA 218.A N LYS 214.A O no hydrogen 3.001 N/A LEU 219.A N GLU 215.A O no hydrogen 3.269 N/A GLU 220.A N GLU 216.A O no hydrogen 2.989 N/A ILE 221.A N CYS 217.A O no hydrogen 3.090 N/A ILE 222.A N ALA 218.A O no hydrogen 3.254 N/A LYS 223.A N LEU 219.A O no hydrogen 2.839 N/A LYS 223.A NZ GLU 220.A OE1 no hydrogen 3.099 N/A GLY 224.A N GLU 220.A O no hydrogen 3.031 N/A GLY 225.A N ILE 221.A O no hydrogen 2.996 N/A ALA 226.A N ILE 222.A O no hydrogen 2.803 N/A LEU 227.A N LYS 223.A O no hydrogen 2.819 N/A ARG 228.A N GLY 225.A O no hydrogen 3.150 N/A ARG 228.A NH1 ASN 138.A O no hydrogen 2.956 N/A ARG 228.A NH1 GLY 139.A O no hydrogen 3.490 N/A ARG 228.A NH2 ASN 138.A O no hydrogen 3.369 N/A ARG 228.A NH2 GLY 139.A O no hydrogen 3.421 N/A ARG 228.A NH2 ASN 183.A O no hydrogen 2.996 N/A GLN 229.A N GLY 224.A O no hydrogen 2.968 N/A VAL 232.A N LEU 188.A O no hydrogen 2.910 N/A TYR 233.A OH GLU 231.A OE2 no hydrogen 2.636 N/A TYR 234.A N VAL 190.A O no hydrogen 3.018 N/A TYR 234.A OH GLU 216.A OE1 no hydrogen 2.707 N/A SER 236.A OG GLN 210.A O no hydrogen 2.860 N/A SER 237.A N ASP 235.A OD1 no hydrogen 3.004 N/A TRP 239.A N SER 237.A OG no hydrogen 3.157 N/A THR 240.A N SER 237.A O no hydrogen 3.285 N/A THR 240.A OG1 ASP 235.A OD1 no hydrogen 2.673 N/A THR 240.A OG1 SER 237.A O no hydrogen 3.406 N/A THR 241.A OG1 LEU 238.A O no hydrogen 2.541 N/A LEU 242.A N LEU 238.A O no hydrogen 3.275 N/A LEU 243.A N TRP 239.A O no hydrogen 3.219 N/A LEU 243.A N THR 240.A O no hydrogen 3.020 N/A ILE 244.A N THR 240.A O no hydrogen 3.055 N/A ARG 249.A NE GLU 253.A OE1 no hydrogen 2.822 N/A ARG 249.A NH1 ASP 167.A OD1 no hydrogen 3.348 N/A ARG 249.A NH1 ASP 167.A OD2 no hydrogen 2.788 N/A ARG 249.A NH2 ASP 167.A OD1 no hydrogen 2.807 N/A LYS 250.A N ASN 246.A O no hydrogen 3.394 N/A LYS 250.A NZ GLU 253.A OE2 no hydrogen 2.814 N/A ILE 251.A N PRO 247.A O no hydrogen 3.075 N/A LEU 252.A N SER 248.A O no hydrogen 2.928 N/A GLU 253.A N ARG 249.A O no hydrogen 2.883 N/A PHE 254.A N LYS 250.A O no hydrogen 3.126 N/A LEU 255.A N ILE 251.A O no hydrogen 2.827 N/A TYR 256.A N LEU 252.A O no hydrogen 2.874 N/A SER 257.A N GLU 253.A O no hydrogen 2.981 N/A SER 257.A OG PHE 254.A O no hydrogen 2.607 N/A THR 258.A OG1 LEU 255.A O no hydrogen 2.849 N/A SER 259.A N TYR 256.A O no hydrogen 3.187 N/A TYR 260.A N SER 257.A O no hydrogen 3.257 N/A