Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4hyq_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 1.A N ASN 43.A O no hydrogen 3.224 N/A ALA 1.A N SER 44.A O no hydrogen 3.468 N/A GLY 4.A N SER 72.A O no hydrogen 3.009 N/A TYR 5.A N SER 47.A O no hydrogen 2.879 N/A TYR 5.A OH SER 77.A OG no hydrogen 2.733 N/A VAL 6.A N LEU 75.A O no hydrogen 2.925 N/A ALA 7.A N ASP 49.A O no hydrogen 2.940 N/A LEU 8.A N SER 77.A O no hydrogen 2.898 N/A GLY 9.A N GLN 65.A OE1 no hydrogen 2.802 N/A ASP 10.A N THR 79.A O no hydrogen 2.966 N/A SER 11.A OG HIS 218.A NE2 no hydrogen 2.652 N/A TYR 12.A N ASP 10.A OD1 no hydrogen 3.156 N/A TYR 12.A OH TYR 217.A O no hydrogen 2.813 N/A SER 13.A N ASP 10.A O no hydrogen 2.972 N/A SER 13.A OG LEU 8.A O no hydrogen 3.560 N/A SER 13.A OG TYR 35.A OH no hydrogen 2.665 N/A SER 13.A OG THR 79.A OG1 no hydrogen 2.520 N/A SER 14.A N ASP 10.A O no hydrogen 2.883 N/A SER 14.A OG SER 11.A O no hydrogen 3.408 N/A SER 14.A OG CYS 28.A O no hydrogen 3.200 N/A SER 14.A OG ARG 29.A O no hydrogen 2.937 N/A GLY 15.A N SER 11.A O no hydrogen 3.030 N/A VAL 16.A N SER 11.A O no hydrogen 3.086 N/A GLY 17.A N TYR 21.A OH no hydrogen 2.737 N/A ALA 18.A N GLY 15.A O no hydrogen 2.882 N/A GLY 19.A N TYR 21.A OH no hydrogen 3.112 N/A ASP 22.A N ARG 30.A O no hydrogen 2.794 N/A GLY 24.A N ASP 22.A OD1 no hydrogen 2.731 N/A SER 25.A N ASP 22.A O no hydrogen 2.987 N/A SER 25.A OG ASP 22.A O no hydrogen 2.803 N/A GLY 26.A N SER 23.A O no hydrogen 3.008 N/A CYS 28.A N SER 25.A O no hydrogen 2.953 N/A ARG 29.A N GLY 26.A O no hydrogen 3.133 N/A ARG 30.A N SER 25.A OG no hydrogen 2.999 N/A ARG 30.A NH1 ALA 52.A O no hydrogen 2.931 N/A THR 31.A N SER 14.A O no hydrogen 3.087 N/A THR 31.A OG1 GLY 19.A O no hydrogen 2.727 N/A THR 31.A OG1 SER 20.A O no hydrogen 3.245 N/A LYS 33.A N THR 31.A OG1 no hydrogen 2.932 N/A ALA 34.A N THR 31.A O no hydrogen 3.055 N/A TYR 35.A N GLN 224.A OE1 no hydrogen 2.784 N/A TYR 35.A OH SER 13.A OG no hydrogen 2.665 N/A LEU 38.A N ALA 34.A O no hydrogen 3.037 N/A TRP 39.A N TYR 35.A O no hydrogen 2.831 N/A ALA 40.A N PRO 36.A O no hydrogen 2.918 N/A ALA 41.A N ALA 37.A O no hydrogen 3.007 N/A ALA 42.A N LEU 38.A O no hydrogen 3.213 N/A ASN 43.A N TRP 39.A O no hydrogen 2.859 N/A ASN 43.A ND2 TRP 39.A O no hydrogen 2.873 N/A SER 44.A N ALA 40.A O no hydrogen 2.980 N/A ALA 46.A N ALA 1.A O no hydrogen 3.199 N/A ALA 46.A N GLY 3.A O no hydrogen 3.108 N/A ASP 49.A N TYR 5.A O no hydrogen 2.987 N/A VAL 51.A N ALA 7.A O no hydrogen 3.006 N/A CYS 53.A N GLY 9.A O no hydrogen 2.873 N/A CYS 53.A SG SER 54.A O no hydrogen 3.790 N/A SER 54.A N CYS 28.A O no hydrogen 2.954 N/A ALA 56.A N CYS 53.A O no hydrogen 3.037 N/A VAL 57.A N ASP 60.A OD2 no hydrogen 3.058 N/A THR 58.A N ASP 84.A OD1 no hydrogen 3.431 N/A THR 58.A N ASP 84.A OD2 no hydrogen 2.769 N/A THR 58.A OG1 ASP 84.A OD1 no hydrogen 2.698 N/A ASP 60.A N VAL 57.A O no hydrogen 2.895 N/A VAL 61.A N VAL 57.A O no hydrogen 3.251 N/A LEU 62.A N THR 58.A O no hydrogen 3.222 N/A ASN 63.A N SER 59.A O no hydrogen 2.901 N/A LYS 64.A N ASP 60.A O no hydrogen 2.726 N/A GLN 65.A N VAL 61.A O no hydrogen 3.046 N/A GLN 65.A NE2 GLY 9.A O no hydrogen 3.129 N/A LEU 69.A N MET 66.A O no hydrogen 3.070 N/A ASN 70.A N THR 73.A OG1 no hydrogen 2.949 N/A SER 72.A N ASN 70.A OD1 no hydrogen 2.742 N/A SER 72.A OG ASN 70.A OD1 no hydrogen 2.370 N/A THR 73.A N ASN 70.A O no hydrogen 3.059 N/A THR 73.A OG1 ASN 70.A O no hydrogen 3.136 N/A SER 74.A N GLY 4.A O no hydrogen 2.817 N/A SER 74.A OG ALA 2.A O no hydrogen 2.452 N/A SER 74.A OG GLY 4.A O no hydrogen 3.524 N/A LEU 75.A N GLY 4.A O no hydrogen 3.158 N/A VAL 76.A N ASN 136.A O no hydrogen 2.891 N/A SER 77.A N VAL 6.A O no hydrogen 3.135 N/A SER 77.A OG TYR 5.A OH no hydrogen 2.733 N/A LEU 78.A N VAL 138.A O no hydrogen 3.010 N/A THR 79.A OG1 ASP 10.A OD1 no hydrogen 2.779 N/A THR 79.A OG1 SER 13.A OG no hydrogen 2.520 N/A GLY 82.A N TYR 142.A OH no hydrogen 3.058 N/A ASN 83.A ND2 ALA 56.A O no hydrogen 3.190 N/A ALA 85.A N GLY 81.A O no hydrogen 3.218 N/A GLY 86.A N ASN 83.A O no hydrogen 3.012 N/A PHE 87.A N GLY 82.A O no hydrogen 3.224 N/A VAL 90.A N GLY 86.A O no hydrogen 2.908 N/A MET 91.A N PHE 87.A O no hydrogen 2.853 N/A THR 92.A N ALA 88.A O no hydrogen 3.001 N/A THR 92.A OG1 ALA 88.A O no hydrogen 3.063 N/A THR 93.A N ASP 89.A O no hydrogen 2.952 N/A THR 93.A OG1 ASP 89.A O no hydrogen 3.055 N/A CYS 94.A N VAL 90.A O no hydrogen 2.884 N/A CYS 94.A SG VAL 90.A O no hydrogen 3.345 N/A VAL 95.A N MET 91.A O no hydrogen 2.942 N/A LEU 96.A N THR 92.A O no hydrogen 2.972 N/A GLN 97.A N THR 93.A O no hydrogen 2.850 N/A ASN 101.A N SER 98.A OG no hydrogen 3.143 N/A CYS 102.A N SER 98.A O no hydrogen 2.908 N/A ILE 103.A N GLU 99.A O no hydrogen 2.926 N/A ALA 104.A N ALA 100.A O no hydrogen 3.094 N/A ARG 105.A N ASN 101.A O no hydrogen 3.010 N/A ARG 105.A NE ASP 89.A OD2 no hydrogen 2.790 N/A ARG 105.A NH1 ARG 105.A O no hydrogen 2.968 N/A ARG 105.A NH2 ASP 89.A OD2 no hydrogen 3.272 N/A VAL 106.A N CYS 102.A O no hydrogen 2.847 N/A ASN 107.A N ILE 103.A O no hydrogen 2.831 N/A THR 108.A N ALA 104.A O no hydrogen 3.079 N/A THR 108.A OG1 ALA 104.A O no hydrogen 3.363 N/A ALA 109.A N ARG 105.A O no hydrogen 3.083 N/A LYS 110.A N VAL 106.A O no hydrogen 2.851 N/A ALA 111.A N ASN 107.A O no hydrogen 3.013 N/A PHE 112.A N THR 108.A O no hydrogen 3.238 N/A VAL 113.A N ALA 109.A O no hydrogen 2.928 N/A GLU 114.A N LYS 110.A O no hydrogen 3.076 N/A SER 115.A N ALA 111.A O no hydrogen 3.064 N/A SER 115.A OG ALA 111.A O no hydrogen 2.922 N/A SER 115.A OG THR 116.A OG1 no hydrogen 3.265 N/A THR 116.A N PHE 112.A O no hydrogen 2.822 N/A THR 116.A OG1 SER 115.A OG no hydrogen 3.265 N/A LEU 117.A N PHE 112.A O no hydrogen 3.021 N/A ARG 120.A NH1 ASP 84.A OD1 no hydrogen 2.947 N/A LEU 121.A N LEU 117.A O no hydrogen 2.909 N/A ASP 122.A N PRO 118.A O no hydrogen 2.902 N/A SER 123.A N GLY 119.A O no hydrogen 3.096 N/A VAL 124.A N ARG 120.A O no hydrogen 3.056 N/A TYR 125.A N LEU 121.A O no hydrogen 2.771 N/A SER 126.A N ASP 122.A O no hydrogen 2.809 N/A SER 126.A OG ASP 122.A O no hydrogen 3.083 N/A GLN 127.A N SER 123.A O no hydrogen 3.177 N/A VAL 128.A N VAL 124.A O no hydrogen 2.980 N/A ARG 129.A N TYR 125.A O no hydrogen 3.239 N/A ARG 129.A NH1 ALA 132.A O no hydrogen 2.843 N/A ARG 129.A NH1 ALA 135.A O no hydrogen 2.884 N/A ARG 129.A NH2 ALA 135.A O no hydrogen 3.094 N/A ALA 130.A N SER 126.A O no hydrogen 2.989 N/A LYS 131.A N GLN 127.A O no hydrogen 3.137 N/A LYS 131.A NZ MET 66.A O no hydrogen 2.986 N/A LYS 131.A NZ GLY 67.A O no hydrogen 2.942 N/A LYS 131.A NZ LEU 69.A O no hydrogen 2.640 N/A ALA 132.A N VAL 128.A O no hydrogen 2.939 N/A ALA 135.A N ALA 132.A O no hydrogen 3.367 N/A ASN 136.A N SER 74.A O no hydrogen 2.907 N/A ASN 136.A ND2 LYS 235.A O no hydrogen 2.895 N/A ASN 136.A ND2 ALA 236.A O no hydrogen 2.706 N/A VAL 138.A N VAL 76.A O no hydrogen 2.794 N/A VAL 139.A N ALA 185.A O no hydrogen 2.888 N/A LEU 140.A N LEU 78.A O no hydrogen 2.938 N/A GLY 141.A N GLY 187.A O no hydrogen 2.951 N/A TYR 142.A N ASN 172.A OD1 no hydrogen 2.834 N/A TYR 142.A OH ASP 10.A OD2 no hydrogen 2.617 N/A ARG 144.A NE ASP 169.A OD1 no hydrogen 2.863 N/A ARG 144.A NH2 ASP 169.A OD1 no hydrogen 3.413 N/A ARG 144.A NH2 ASP 169.A OD2 no hydrogen 2.854 N/A TYR 146.A N ASN 165.A OD1 no hydrogen 3.113 N/A TYR 146.A OH TYR 217.A OH no hydrogen 2.740 N/A LYS 147.A N ILE 198.A O no hydrogen 2.988 N/A GLY 155.A N CYS 152.A O no hydrogen 3.236 N/A THR 157.A N GLU 160.A OE1 no hydrogen 3.134 N/A THR 157.A OG1 GLU 99.A OE1 no hydrogen 2.731 N/A THR 157.A OG1 GLU 160.A OE1 no hydrogen 3.263 N/A GLU 160.A N THR 157.A OG1 no hydrogen 3.209 N/A ARG 161.A N THR 157.A O no hydrogen 2.894 N/A ARG 161.A NE GLY 155.A O no hydrogen 2.589 N/A ARG 161.A NE LEU 156.A O no hydrogen 3.211 N/A ARG 161.A NH1 ASN 149.A OD1 no hydrogen 3.371 N/A ARG 161.A NH2 LEU 156.A O no hydrogen 3.122 N/A THR 162.A N GLU 158.A O no hydrogen 2.851 N/A THR 162.A OG1 GLU 158.A O no hydrogen 2.931 N/A ALA 163.A N GLY 159.A O no hydrogen 3.109 N/A ILE 164.A N GLU 160.A O no hydrogen 2.875 N/A ASN 165.A N ARG 161.A O no hydrogen 2.897 N/A ASN 165.A ND2 TYR 146.A O no hydrogen 2.868 N/A GLY 166.A N THR 162.A O no hydrogen 2.935 N/A ALA 167.A N ALA 163.A O no hydrogen 3.007 N/A ALA 168.A N ILE 164.A O no hydrogen 3.044 N/A ASP 169.A N ASN 165.A O no hydrogen 2.948 N/A LEU 170.A N GLY 166.A O no hydrogen 3.073 N/A LEU 171.A N ALA 167.A O no hydrogen 2.919 N/A ASN 172.A N ALA 168.A O no hydrogen 2.818 N/A ASN 172.A ND2 TYR 142.A O no hydrogen 2.845 N/A SER 173.A N ASP 169.A O no hydrogen 2.888 N/A VAL 174.A N LEU 170.A O no hydrogen 3.026 N/A ILE 175.A N LEU 171.A O no hydrogen 2.972 N/A SER 176.A N ASN 172.A O no hydrogen 2.854 N/A SER 176.A OG ASN 172.A O no hydrogen 2.950 N/A SER 176.A OG SER 173.A O no hydrogen 2.788 N/A LYS 177.A N SER 173.A O no hydrogen 3.057 N/A ARG 178.A N VAL 174.A O no hydrogen 2.970 N/A ARG 178.A NH1 ASP 122.A OD1 no hydrogen 2.815 N/A ARG 178.A NH1 ASP 181.A OD2 no hydrogen 3.363 N/A ALA 179.A N ILE 175.A O no hydrogen 2.834 N/A ALA 180.A N SER 176.A O no hydrogen 3.031 N/A ASP 181.A N LYS 177.A O no hydrogen 3.061 N/A HIS 182.A N ARG 178.A O no hydrogen 3.305 N/A HIS 182.A N ALA 179.A O no hydrogen 3.035 N/A HIS 182.A NE2 ASP 122.A OD1 no hydrogen 2.733 N/A GLY 183.A N ALA 180.A O no hydrogen 2.990 N/A TYR 184.A N ALA 179.A O no hydrogen 2.887 N/A TYR 184.A OH TYR 125.A O no hydrogen 2.591 N/A ALA 185.A N VAL 137.A O no hydrogen 2.929 N/A GLY 187.A N VAL 139.A O no hydrogen 2.799 N/A ILE 189.A N GLY 187.A O no hydrogen 2.972 N/A ALA 191.A N ASP 188.A OD1 no hydrogen 2.913 N/A ALA 192.A N ASP 188.A O no hydrogen 3.186 N/A PHE 193.A N ILE 189.A O no hydrogen 2.812 N/A THR 194.A N ALA 191.A O no hydrogen 3.155 N/A THR 194.A OG1 ALA 190.A O no hydrogen 2.963 N/A THR 194.A OG1 ALA 191.A O no hydrogen 3.244 N/A GLY 195.A N GLU 197.A OE1 no hydrogen 2.834 N/A HIS 196.A N PHE 193.A O no hydrogen 2.800 N/A HIS 196.A ND1 ASP 202.A O no hydrogen 2.813 N/A GLU 197.A N GLU 197.A OE1 no hydrogen 2.765 N/A ILE 198.A N PHE 145.A O no hydrogen 2.900 N/A SER 200.A N GLU 197.A O no hydrogen 3.104 N/A SER 200.A OG GLY 195.A O no hydrogen 3.376 N/A SER 200.A OG GLU 197.A O no hydrogen 2.618 N/A ASP 202.A N SER 200.A OG no hydrogen 3.160 N/A SER 203.A OG GLU 197.A O no hydrogen 3.357 N/A SER 203.A OG LEU 205.A O no hydrogen 2.843 N/A TRP 204.A N HIS 196.A O no hydrogen 2.753 N/A LEU 205.A N SER 203.A OG no hydrogen 2.967 N/A HIS 206.A N HIS 218.A O no hydrogen 2.875 N/A HIS 206.A NE2 GLY 17.A O no hydrogen 2.621 N/A LYS 209.A N SER 216.A OG no hydrogen 2.790 N/A LYS 209.A NZ HIS 206.A ND1 no hydrogen 3.312 N/A TYR 217.A N HIS 206.A O no hydrogen 2.843 N/A TYR 217.A OH TYR 146.A OH no hydrogen 2.740 N/A HIS 218.A N ASP 215.A O no hydrogen 3.105 N/A HIS 218.A ND1 SER 216.A O no hydrogen 2.873 N/A HIS 218.A NE2 SER 11.A OG no hydrogen 2.652 N/A THR 220.A N TRP 204.A O no hydrogen 2.885 N/A THR 220.A OG1 TRP 204.A O no hydrogen 3.387 N/A GLY 223.A N THR 220.A OG1 no hydrogen 3.139 N/A GLN 224.A N THR 220.A O no hydrogen 3.004 N/A GLN 224.A NE2 TYR 12.A O no hydrogen 3.148 N/A SER 225.A N ALA 221.A O no hydrogen 3.036 N/A SER 225.A OG ALA 221.A O no hydrogen 3.266 N/A SER 225.A OG ALA 222.A O no hydrogen 3.546 N/A GLY 226.A N ALA 222.A O no hydrogen 2.737 N/A GLY 227.A N GLY 223.A O no hydrogen 2.908 N/A TYR 228.A N GLY 223.A O no hydrogen 3.027 N/A LEU 229.A N GLN 224.A O no hydrogen 2.912 N/A VAL 231.A N GLY 227.A O no hydrogen 3.452 N/A LEU 232.A N TYR 228.A O no hydrogen 2.980 N/A ASN 233.A N LEU 229.A O no hydrogen 2.809 N/A SER 234.A N PRO 230.A O no hydrogen 2.982 N/A SER 234.A OG VAL 231.A O no hydrogen 2.607 N/A LYS 235.A N LEU 232.A O no hydrogen 3.040 N/A ALA 236.A N LEU 232.A O no hydrogen 2.813 N/A