Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4hzr_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): CYS 3.A N TYR 65.A O no hydrogen 3.002 N/A ILE 5.A N VAL 67.A O.A no hydrogen 2.815 N/A ILE 5.A N VAL 67.A O.B no hydrogen 2.921 N/A LYS 8.A NZ ASP 9.A OD2 no hydrogen 2.964 N/A ASP 9.A N GLY 6.A O no hydrogen 2.955 N/A LEU 10.A N GLU 7.A O no hydrogen 3.209 N/A ARG 11.A N GLU 25.A O no hydrogen 2.910 N/A ARG 11.A NE GLU 25.A OE2 no hydrogen 3.325 N/A ARG 11.A NH1 ASP 27.A OD1 no hydrogen 2.650 N/A ARG 11.A NH1 ASP 27.A OD2 no hydrogen 3.411 N/A ARG 11.A NH2 GLU 25.A OE2 no hydrogen 2.925 N/A ARG 11.A NH2 ASP 27.A OD2 no hydrogen 3.031 N/A LEU 13.A N ARG 23.A O no hydrogen 2.705 N/A GLU 14.A N GLU 14.A OE1 no hydrogen 2.751 N/A LYS 15.A NZ ASP 18.A OD1 no hydrogen 2.926 N/A LEU 16.A N VAL 21.A O no hydrogen 2.744 N/A GLY 17.A N VAL 21.A O no hydrogen 3.327 N/A VAL 21.A N GLY 17.A O no hydrogen 3.041 N/A ARG 22.A N VAL 38.A O no hydrogen 2.877 N/A ARG 22.A NE LEU 13.A O no hydrogen 2.804 N/A ARG 22.A NH2 LEU 13.A O no hydrogen 2.844 N/A ARG 23.A N GLU 14.A O no hydrogen 2.856 N/A ARG 23.A NH1 GLU 14.A OE2 no hydrogen 3.268 N/A GLY 24.A N VAL 36.A O no hydrogen 2.861 N/A GLU 25.A N ARG 11.A O no hydrogen 2.905 N/A TRP 26.A N VAL 34.A O no hydrogen 2.801 N/A ASP 27.A N ASP 9.A O no hydrogen 2.849 N/A ALA 28.A N LYS 32.A O no hydrogen 3.007 N/A GLY 31.A N ALA 28.A O no hydrogen 2.912 N/A LYS 32.A N SER 30.A OG no hydrogen 3.345 N/A VAL 34.A N TRP 26.A O no hydrogen 2.812 N/A VAL 36.A N GLY 24.A O no hydrogen 2.995 N/A ALA 37.A N THR 77.A O no hydrogen 2.884 N/A VAL 38.A N ARG 22.A O no hydrogen 2.692 N/A LYS 39.A N MET 75.A O no hydrogen 2.850 N/A LYS 39.A NZ GLU 49.A OE1 no hydrogen 3.268 N/A LYS 39.A NZ ASP 142.A OD2 no hydrogen 3.293 N/A CYS 40.A N VAL 20.A O no hydrogen 2.995 N/A CYS 40.A SG VAL 20.A O no hydrogen 3.800 N/A CYS 40.A SG VAL 38.A O no hydrogen 4.001 N/A LEU 41.A N MET 73.A O no hydrogen 2.771 N/A PHE 46.A N ALA 42.A O no hydrogen 2.873 N/A ILE 47.A N MET 43.A O no hydrogen 2.912 N/A ARG 48.A N ASP 44.A O no hydrogen 2.878 N/A ARG 48.A NH1 ASP 44.A OD1 no hydrogen 3.312 N/A ARG 48.A NH1 ASP 44.A OD2 no hydrogen 2.860 N/A ARG 48.A NH2 ASP 44.A OD2 no hydrogen 2.777 N/A ARG 48.A NH2 ASP 45.A OD1 no hydrogen 2.778 N/A GLU 49.A N ASP 45.A O no hydrogen 2.919 N/A VAL 50.A N PHE 46.A O no hydrogen 3.033 N/A ASN 51.A N ILE 47.A O no hydrogen 2.884 N/A ALA 52.A N ARG 48.A O no hydrogen 2.913 N/A MET 53.A N GLU 49.A O no hydrogen 2.867 N/A HIS 54.A N VAL 50.A O no hydrogen 2.878 N/A SER 55.A OG HIS 54.A O no hydrogen 2.446 N/A LEU 56.A N MET 53.A O no hydrogen 3.069 N/A ASP 57.A N TYR 114.A OH no hydrogen 3.025 N/A ASN 60.A ND2 VAL 138.A O.A no hydrogen 3.079 N/A ASN 60.A ND2 VAL 138.A O.B no hydrogen 3.066 N/A LEU 61.A N HIS 58.A O no hydrogen 3.034 N/A ILE 62.A N ILE 140.A O no hydrogen 2.975 N/A ARG 63.A N GLU 78.A OE2 no hydrogen 3.062 N/A TYR 65.A N VAL 76.A O no hydrogen 2.805 N/A GLY 66.A N VAL 76.A O no hydrogen 3.216 N/A VAL 67.A N.A CYS 3.A O no hydrogen 2.975 N/A VAL 67.A N.B CYS 3.A O no hydrogen 2.978 N/A VAL 68.A N LYS 74.A O no hydrogen 2.886 N/A LYS 74.A N VAL 68.A O no hydrogen 3.007 N/A LYS 74.A NZ PRO 72.A O no hydrogen 2.800 N/A MET 75.A N LYS 39.A O no hydrogen 2.841 N/A VAL 76.A N GLY 66.A O no hydrogen 2.877 N/A THR 77.A N ALA 37.A O no hydrogen 2.803 N/A THR 77.A OG1 ALA 37.A O no hydrogen 3.461 N/A THR 77.A OG1 GLU 78.A O no hydrogen 3.074 N/A GLU 78.A N ARG 63.A O no hydrogen 2.867 N/A LEU 82.A N LEU 132.A O no hydrogen 3.027 N/A GLY 83.A N ALA 80.A O no hydrogen 3.009 N/A LEU 85.A N LEU 130.A O no hydrogen 3.075 N/A ASP 87.A N SER 84.A OG no hydrogen 3.040 N/A ARG 88.A N SER 84.A O no hydrogen 3.340 N/A ARG 88.A NE LEU 82.A O no hydrogen 2.651 N/A ARG 88.A NH2 LEU 82.A O no hydrogen 3.112 N/A LEU 89.A N LEU 85.A O no hydrogen 2.866 N/A ARG 90.A N LEU 86.A O no hydrogen 3.096 N/A ARG 90.A NE GLY 199.A O no hydrogen 2.830 N/A ARG 90.A NH2 GLY 199.A O no hydrogen 3.254 N/A LYS 91.A N ASP 87.A O no hydrogen 3.066 N/A HIS 92.A N ARG 88.A O no hydrogen 2.850 N/A HIS 95.A N HIS 92.A O no hydrogen 2.995 N/A PHE 96.A N GLN 93.A O no hydrogen 3.008 N/A LEU 101.A N LEU 97.A O no hydrogen 3.086 N/A SER 102.A N LEU 98.A O no hydrogen 2.970 N/A SER 102.A OG LEU 98.A O no hydrogen 3.132 N/A ARG 103.A N GLY 99.A O no hydrogen 3.056 N/A TYR 104.A N THR 100.A O no hydrogen 2.946 N/A TYR 104.A OH ARG 135.A O no hydrogen 2.579 N/A ALA 105.A N LEU 101.A O no hydrogen 2.943 N/A VAL 106.A N SER 102.A O no hydrogen 3.265 N/A GLN 107.A N ARG 103.A O no hydrogen 3.038 N/A GLN 107.A NE2 ASP 136.A O no hydrogen 2.864 N/A VAL 108.A N TYR 104.A O no hydrogen 2.871 N/A ALA 109.A N ALA 105.A O no hydrogen 3.068 N/A GLU 110.A N VAL 106.A O no hydrogen 2.875 N/A GLY 111.A N GLN 107.A O no hydrogen 2.999 N/A MET 112.A N VAL 108.A O no hydrogen 2.934 N/A GLY 113.A N ALA 109.A O no hydrogen 2.823 N/A TYR 114.A N GLU 110.A O no hydrogen 3.073 N/A LEU 115.A N GLY 111.A O no hydrogen 3.119 N/A GLU 116.A N MET 112.A O no hydrogen 2.777 N/A SER 117.A N GLY 113.A O no hydrogen 2.944 N/A SER 117.A OG TYR 114.A O no hydrogen 2.720 N/A LYS 118.A N LEU 115.A O no hydrogen 3.017 N/A ARG 119.A N GLU 116.A O no hydrogen 2.986 N/A ARG 119.A NH2 PRO 150.A O no hydrogen 2.930 N/A ARG 119.A NH2 ASP 153.A O no hydrogen 3.067 N/A PHE 120.A N LEU 115.A O no hydrogen 3.045 N/A ILE 121.A N ARG 147.A O no hydrogen 2.852 N/A HIS 122.A N ASP 184.A OD2 no hydrogen 2.789 N/A HIS 122.A NE2 ASP 142.A O no hydrogen 2.756 N/A ARG 123.A N ASP 184.A OD1 no hydrogen 2.937 N/A ARG 123.A NE LEU 145.A O no hydrogen 2.754 N/A ARG 123.A NH2 LEU 145.A O no hydrogen 2.940 N/A ASP 124.A N HIS 122.A ND1 no hydrogen 3.125 N/A ALA 127.A N GLU 194.A OE2 no hydrogen 2.827 N/A ARG 128.A NH2 ASP 124.A OD1 no hydrogen 3.054 N/A ASN 129.A N ALA 126.A O no hydrogen 2.926 N/A ASN 129.A ND2 ASP 124.A O no hydrogen 2.798 N/A ASN 129.A ND2 ASP 124.A OD2 no hydrogen 3.146 N/A LEU 130.A N ALA 127.A O no hydrogen 3.037 N/A LEU 131.A N LYS 139.A O no hydrogen 2.803 N/A LEU 132.A N GLY 83.A O no hydrogen 2.781 N/A ALA 133.A N LEU 137.A O no hydrogen 2.886 N/A THR 134.A N LEU 137.A O no hydrogen 3.394 N/A ASP 136.A N THR 134.A OG1 no hydrogen 3.057 N/A LEU 137.A N THR 134.A O no hydrogen 3.183 N/A VAL 138.A N.A GLN 107.A OE1 no hydrogen 2.855 N/A VAL 138.A N.B GLN 107.A OE1 no hydrogen 2.850 N/A LYS 139.A N LEU 131.A O no hydrogen 2.837 N/A LYS 139.A NZ ARG 59.A O no hydrogen 2.852 N/A LYS 139.A NZ GLU 78.A OE1 no hydrogen 2.730 N/A ILE 140.A N ASN 60.A O no hydrogen 2.863 N/A GLY 141.A N ASN 129.A O no hydrogen 2.822 N/A PHE 143.A N GLU 49.A OE2 no hydrogen 3.203 N/A GLY 144.A N ASP 142.A OD1 no hydrogen 2.990 N/A MET 146.A N PHE 143.A O no hydrogen 3.130 N/A ARG 147.A N ILE 121.A O no hydrogen 2.939 N/A ARG 147.A NH1 MET 146.A O no hydrogen 2.876 N/A LEU 149.A N ARG 119.A O no hydrogen 2.779 N/A ASP 153.A N PRO 150.A O no hydrogen 3.029 N/A HIS 155.A ND1 ASP 154.A OD1 no hydrogen 2.695 N/A TYR 156.A N PHE 179.A O no hydrogen 2.800 N/A MET 158.A N ARG 177.A O no hydrogen 2.858 N/A ARG 162.A N GLN 159.A O no hydrogen 3.141 N/A ARG 162.A NH1 ASP 45.A OD2 no hydrogen 2.772 N/A ARG 162.A NH2 ASP 45.A OD1 no hydrogen 2.604 N/A ARG 162.A NH2 ASP 45.A OD2 no hydrogen 3.406 N/A TRP 168.A N PRO 165.A O no hydrogen 3.401 N/A TRP 168.A NE1 GLU 194.A OE2 no hydrogen 2.783 N/A CYS 169.A N PHE 166.A O no hydrogen 3.020 N/A CYS 169.A SG VAL 164.A O no hydrogen 3.992 N/A CYS 169.A SG PRO 165.A O no hydrogen 3.640 N/A GLU 172.A N GLU 172.A OE1 no hydrogen 2.788 N/A SER 173.A OG THR 178.A O no hydrogen 2.723 N/A LEU 174.A N ALA 170.A O no hydrogen 3.027 N/A LYS 175.A N PRO 171.A O no hydrogen 2.902 N/A LYS 175.A NZ ASP 216.A OD1 no hydrogen 2.793 N/A THR 176.A N GLU 172.A O no hydrogen 3.019 N/A THR 176.A OG1 GLU 172.A O no hydrogen 3.169 N/A THR 176.A OG1 THR 178.A OG1 no hydrogen 2.718 N/A ARG 177.A N SER 173.A O no hydrogen 2.956 N/A ARG 177.A NE MET 158.A O no hydrogen 2.846 N/A ARG 177.A NH2 GLN 159.A O no hydrogen 2.878 N/A ARG 177.A NH2 ARG 162.A O no hydrogen 3.082 N/A THR 178.A N GLU 172.A O no hydrogen 3.270 N/A THR 178.A OG1 THR 176.A OG1 no hydrogen 2.718 N/A PHE 179.A N TYR 156.A O no hydrogen 2.830 N/A SER 180.A N SER 183.A OG no hydrogen 2.844 N/A SER 183.A N SER 180.A OG no hydrogen 3.098 N/A SER 183.A OG SER 180.A O no hydrogen 3.046 N/A ASP 184.A N SER 180.A O no hydrogen 3.092 N/A THR 185.A N HIS 181.A O no hydrogen 2.951 N/A THR 185.A OG1 HIS 181.A O no hydrogen 3.542 N/A THR 185.A OG1 PRO 248.A O no hydrogen 2.918 N/A TRP 186.A N ALA 182.A O no hydrogen 3.097 N/A MET 187.A N SER 183.A O no hydrogen 2.981 N/A PHE 188.A N ASP 184.A O no hydrogen 2.836 N/A GLY 189.A N THR 185.A O no hydrogen 3.049 N/A VAL 190.A N TRP 186.A O no hydrogen 3.174 N/A THR 191.A N MET 187.A O no hydrogen 2.896 N/A THR 191.A OG1 MET 187.A O no hydrogen 2.980 N/A LEU 192.A N PHE 188.A O no hydrogen 2.862 N/A TRP 193.A N GLY 189.A O no hydrogen 3.044 N/A TRP 193.A NE1 PRO 223.A O no hydrogen 2.736 N/A GLU 194.A N VAL 190.A O no hydrogen 2.904 N/A MET 195.A N THR 191.A O no hydrogen 3.028 N/A PHE 196.A N LEU 192.A O no hydrogen 2.981 N/A THR 197.A N TRP 193.A O no hydrogen 2.973 N/A THR 197.A OG1 TRP 193.A O no hydrogen 2.935 N/A THR 197.A OG1 GLU 194.A O no hydrogen 3.154 N/A TYR 198.A N MET 195.A O no hydrogen 2.969 N/A TYR 198.A OH PHE 96.A O no hydrogen 3.380 N/A GLY 199.A N GLU 194.A O no hydrogen 2.764 N/A GLN 200.A N THR 197.A OG1 no hydrogen 3.144 N/A LEU 206.A N TRP 203.A O no hydrogen 3.140 N/A ASN 207.A N GLN 210.A OE1 no hydrogen 2.944 N/A GLN 210.A N ASN 207.A OD1 no hydrogen 2.898 N/A ILE 211.A N ASN 207.A O no hydrogen 2.959 N/A LEU 212.A N GLY 208.A O no hydrogen 2.914 N/A HIS 213.A N SER 209.A O no hydrogen 2.942 N/A HIS 213.A ND1 GLU 218.A OE1 no hydrogen 2.944 N/A LYS 214.A N GLN 210.A O no hydrogen 3.018 N/A LYS 214.A NZ GLU 220.A OE1 no hydrogen 2.994 N/A ILE 215.A N ILE 211.A O no hydrogen 2.992 N/A ASP 216.A N LEU 212.A O no hydrogen 2.838 N/A LYS 217.A N HIS 213.A O no hydrogen 2.967 N/A GLU 218.A N HIS 213.A O no hydrogen 3.061 N/A GLU 220.A N LYS 214.A O no hydrogen 2.912 N/A ARG 221.A NE TRP 240.A O no hydrogen 3.048 N/A ARG 221.A NH1 ILE 215.A O no hydrogen 2.992 N/A ARG 221.A NH1 GLU 220.A O no hydrogen 2.882 N/A ARG 221.A NH2 TRP 240.A O no hydrogen 2.887 N/A ARG 224.A NH1 CYS 228.A O no hydrogen 2.900 N/A CYS 228.A N PRO 225.A O no hydrogen 2.979 N/A CYS 228.A SG PRO 229.A O no hydrogen 3.514 N/A GLN 230.A NE2 ASN 234.A OD1 no hydrogen 2.887 N/A TYR 233.A N PRO 229.A O no hydrogen 3.060 N/A TYR 233.A OH LEU 222.A O no hydrogen 2.670 N/A ASN 234.A N GLN 230.A O no hydrogen 2.823 N/A VAL 235.A N ASP 231.A O no hydrogen 3.273 N/A MET 236.A N ILE 232.A O no hydrogen 3.104 N/A VAL 237.A N TYR 233.A O no hydrogen 2.935 N/A GLN 238.A N ASN 234.A O no hydrogen 3.008 N/A GLN 238.A NE2 ASN 234.A O no hydrogen 3.426 N/A CYS 239.A N VAL 235.A O no hydrogen 3.038 N/A CYS 239.A SG VAL 235.A O no hydrogen 3.404 N/A TRP 240.A N VAL 237.A O no hydrogen 3.067 N/A ALA 241.A N GLN 238.A O no hydrogen 3.351 N/A GLU 245.A N GLU 245.A OE1 no hydrogen 2.781 N/A ASP 246.A N LYS 243.A O no hydrogen 2.873 N/A ARG 247.A N PRO 244.A O no hydrogen 3.058 N/A ARG 247.A NE ALA 241.A O no hydrogen 2.807 N/A ARG 247.A NH1 GLU 172.A OE2 no hydrogen 2.818 N/A ARG 247.A NH1 ALA 182.A O no hydrogen 3.037 N/A ARG 247.A NH2 GLU 172.A OE1 no hydrogen 2.912 N/A ARG 247.A NH2 ALA 241.A O no hydrogen 3.366 N/A ARG 247.A NH2 HIS 242.A O no hydrogen 3.040 N/A PHE 250.A N GLU 116.A OE1 no hydrogen 2.973 N/A ALA 252.A N THR 249.A OG1 no hydrogen 3.203 N/A LEU 253.A N THR 249.A O no hydrogen 2.846 N/A ARG 254.A N PHE 250.A O no hydrogen 2.918 N/A ASP 255.A N VAL 251.A O.A no hydrogen 3.297 N/A PHE 256.A N ALA 252.A O no hydrogen 2.914 N/A LEU 257.A N LEU 253.A O no hydrogen 2.833 N/A LEU 258.A N ARG 254.A O no hydrogen 2.888 N/A GLU 259.A N ASP 255.A O no hydrogen 3.014 N/A ALA 260.A N PHE 256.A O no hydrogen 3.008 N/A ALA 260.A N LEU 257.A O no hydrogen 3.162 N/A GLN 261.A N.A LEU 258.A O no hydrogen 3.261 N/A GLN 261.A N.B LEU 258.A O no hydrogen 3.259 N/A GLN 261.A NE2.B SER 102.A O no hydrogen 2.981 N/A GLN 261.A NE2.B LEU 257.A O no hydrogen 2.839 N/A