Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4i9z_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 5.A N GLU 1.A O no hydrogen 3.229 N/A LEU 6.A N GLU 2.A O no hydrogen 2.888 N/A GLN 7.A N THR 3.A O no hydrogen 2.428 N/A SER 8.A N ARG 4.A O no hydrogen 2.806 N/A SER 8.A OG ARG 4.A O no hydrogen 3.063 N/A LEU 9.A N GLU 5.A O no hydrogen 2.873 N/A ALA 10.A N LEU 6.A O no hydrogen 2.795 N/A ALA 11.A N GLN 7.A O no hydrogen 2.980 N/A ALA 12.A N LEU 9.A O no hydrogen 3.322 N/A SER 16.A OG THR 19.A OG1 no hydrogen 2.851 N/A THR 19.A N SER 16.A OG no hydrogen 2.890 N/A THR 19.A OG1 SER 16.A OG no hydrogen 2.851 N/A LEU 20.A N SER 16.A O no hydrogen 3.074 N/A LYS 21.A N GLN 18.A O no hydrogen 3.171 N/A ILE 22.A N ALA 17.A O no hydrogen 3.288 N/A ASP 24.A N LYS 21.A O no hydrogen 3.247 N/A PHE 27.A N ASP 24.A O no hydrogen 3.240 N/A GLU 31.A N GLU 31.A OE1 no hydrogen 2.992 N/A LEU 32.A N ASP 29.A O no hydrogen 2.911 N/A SER 33.A N GLU 36.A OE1 no hydrogen 2.693 N/A SER 33.A OG GLU 36.A OE1 no hydrogen 3.428 N/A GLU 36.A N SER 33.A OG no hydrogen 3.093 N/A THR 37.A N SER 33.A O no hydrogen 2.981 N/A THR 37.A OG1 ASP 34.A O no hydrogen 2.675 N/A ALA 38.A N ASP 34.A O no hydrogen 2.899 N/A LEU 39.A N LEU 35.A O no hydrogen 2.976 N/A CYS 40.A N GLU 36.A O no hydrogen 2.978 N/A CYS 40.A SG GLU 36.A O no hydrogen 3.470 N/A THR 41.A N THR 37.A O no hydrogen 2.955 N/A THR 41.A OG1 THR 37.A O no hydrogen 2.811 N/A ILE 42.A N ALA 38.A O no hydrogen 3.040 N/A ARG 43.A N LEU 39.A O no hydrogen 2.997 N/A ARG 43.A NE PRO 15.A O no hydrogen 2.855 N/A ARG 43.A NH1 ASP 47.A OD1 no hydrogen 2.868 N/A ARG 43.A NH2 VAL 14.A O no hydrogen 2.721 N/A ARG 43.A NH2 PRO 15.A O no hydrogen 3.153 N/A MET 44.A N CYS 40.A O no hydrogen 2.983 N/A PHE 45.A N THR 41.A O no hydrogen 3.102 N/A THR 46.A N ILE 42.A O no hydrogen 2.923 N/A THR 46.A OG1 ARG 43.A O no hydrogen 3.350 N/A THR 46.A OG1 ASP 47.A OD1 no hydrogen 3.068 N/A ASP 47.A N ARG 43.A O no hydrogen 2.922 N/A LEU 48.A N MET 44.A O no hydrogen 3.209 N/A ASN 49.A N THR 46.A O no hydrogen 2.804 N/A LEU 50.A N PHE 45.A O no hydrogen 2.982 N/A ASN 53.A N ASN 49.A O no hydrogen 3.001 N/A PHE 54.A N LEU 50.A O no hydrogen 3.208 N/A GLN 55.A N GLN 52.A O no hydrogen 3.369 N/A GLN 55.A NE2 ASN 53.A O no hydrogen 3.467 N/A MET 56.A N VAL 51.A O no hydrogen 3.144 N/A GLU 59.A N GLU 59.A OE1 no hydrogen 2.748 N/A LEU 61.A N LYS 57.A O no hydrogen 3.115 N/A CYS 62.A N HIS 58.A O no hydrogen 2.946 N/A CYS 62.A SG HIS 58.A O no hydrogen 3.357 N/A ARG 63.A N GLU 59.A O no hydrogen 3.009 N/A ARG 63.A NH1 GLY 156.A O no hydrogen 2.803 N/A TRP 64.A N VAL 60.A O no hydrogen 2.883 N/A ILE 65.A N LEU 61.A O no hydrogen 2.905 N/A LEU 66.A N CYS 62.A O no hydrogen 2.996 N/A SER 67.A N ARG 63.A O no hydrogen 2.846 N/A SER 67.A OG ARG 63.A O no hydrogen 3.128 N/A SER 67.A OG ASN 157.A OD1 no hydrogen 2.673 N/A VAL 68.A N TRP 64.A O no hydrogen 2.972 N/A LYS 69.A N ILE 65.A O no hydrogen 2.938 N/A LYS 69.A NZ GLU 5.A OE1 no hydrogen 2.483 N/A LYS 70.A N LEU 66.A O no hydrogen 2.943 N/A ASN 71.A N SER 67.A O no hydrogen 3.100 N/A ASN 71.A N VAL 68.A O no hydrogen 3.010 N/A ASN 71.A ND2 SER 67.A O no hydrogen 2.562 N/A TYR 72.A N LYS 69.A O no hydrogen 3.241 N/A TYR 72.A OH LEU 117.A O no hydrogen 2.558 N/A ARG 73.A NE ASP 122.A OD2 no hydrogen 3.068 N/A ARG 73.A NH2 ASP 122.A OD2 no hydrogen 3.058 N/A VAL 76.A N ARG 73.A O no hydrogen 3.141 N/A TYR 78.A N GLU 244.A OE2 no hydrogen 2.983 N/A HIS 79.A N GLU 244.A OE2 no hydrogen 2.773 N/A HIS 79.A ND1 GLU 244.A OE1 no hydrogen 2.742 N/A ASN 80.A N TYR 78.A O no hydrogen 2.780 N/A ASN 80.A ND2 VAL 76.A O no hydrogen 2.830 N/A ASN 80.A ND2 ALA 77.A O no hydrogen 2.970 N/A TRP 81.A NE1 THR 37.A OG1 no hydrogen 2.958 N/A ARG 82.A NE ASP 34.A OD1 no hydrogen 3.486 N/A ARG 82.A NH1 LEU 32.A O no hydrogen 2.816 N/A ARG 82.A NH1 ASP 34.A OD1 no hydrogen 3.008 N/A ARG 82.A NH2 ASP 29.A O no hydrogen 3.045 N/A ARG 82.A NH2 ASP 29.A OD2 no hydrogen 2.934 N/A ARG 82.A NH2 LEU 32.A O no hydrogen 3.090 N/A HIS 83.A N ASN 80.A OD1 no hydrogen 3.384 N/A HIS 83.A NE2 ASP 223.A OD2 no hydrogen 3.077 N/A ALA 84.A N ASN 80.A O no hydrogen 3.294 N/A PHE 85.A N TRP 81.A O no hydrogen 2.777 N/A ASN 86.A N ARG 82.A O no hydrogen 2.879 N/A ASN 86.A ND2 ASP 29.A OD1 no hydrogen 2.979 N/A THR 87.A N HIS 83.A O no hydrogen 2.847 N/A THR 87.A OG1 HIS 83.A O no hydrogen 2.806 N/A ALA 88.A N ALA 84.A O no hydrogen 2.905 N/A GLN 89.A N PHE 85.A O no hydrogen 2.961 N/A GLN 89.A NE2 ILE 22.A O no hydrogen 2.772 N/A GLN 89.A NE2 ASP 24.A O no hydrogen 2.856 N/A CYS 90.A N ASN 86.A O no hydrogen 3.007 N/A MET 91.A N THR 87.A O no hydrogen 2.985 N/A PHE 92.A N ALA 88.A O no hydrogen 2.829 N/A ALA 93.A N GLN 89.A O no hydrogen 2.798 N/A ALA 94.A N CYS 90.A O no hydrogen 2.873 N/A LEU 95.A N MET 91.A O no hydrogen 2.955 N/A LYS 96.A N PHE 92.A O no hydrogen 2.855 N/A LYS 96.A NZ ASP 47.A O no hydrogen 2.633 N/A LYS 96.A NZ GLN 101.A OE1 no hydrogen 3.486 N/A GLY 98.A N ALA 93.A O no hydrogen 2.861 N/A LYS 99.A N LYS 96.A O no hydrogen 2.973 N/A ILE 100.A N ALA 94.A O no hydrogen 3.095 N/A GLN 101.A N LEU 95.A O no hydrogen 2.959 N/A LYS 103.A N ILE 100.A O no hydrogen 2.875 N/A LEU 104.A N GLN 101.A O no hydrogen 3.318 N/A THR 105.A N GLU 108.A OE1 no hydrogen 2.856 N/A GLU 108.A N THR 105.A OG1 no hydrogen 3.054 N/A ILE 109.A N THR 105.A O no hydrogen 3.016 N/A LEU 110.A N ASP 106.A O no hydrogen 2.942 N/A ALA 111.A N LEU 107.A O no hydrogen 3.005 N/A LEU 112.A N GLU 108.A O no hydrogen 3.003 N/A LEU 113.A N ILE 109.A O no hydrogen 3.116 N/A ILE 114.A N LEU 110.A O no hydrogen 3.174 N/A ALA 115.A N ALA 111.A O no hydrogen 2.789 N/A ALA 116.A N LEU 112.A O no hydrogen 2.800 N/A LEU 117.A N LEU 113.A O no hydrogen 3.163 N/A SER 118.A N ILE 114.A O no hydrogen 2.893 N/A SER 118.A N ALA 115.A O no hydrogen 2.935 N/A SER 118.A OG ILE 114.A O no hydrogen 2.873 N/A HIS 119.A ND1 ALA 116.A O no hydrogen 2.709 N/A HIS 119.A NE2 ASP 223.A OD2 no hydrogen 3.020 N/A ASP 120.A N TYR 72.A OH no hydrogen 3.239 N/A LEU 121.A N SER 118.A O no hydrogen 3.148 N/A ASP 122.A N ASN 71.A O no hydrogen 2.900 N/A HIS 123.A N ASP 120.A O no hydrogen 3.048 N/A GLY 125.A N HIS 123.A ND1 no hydrogen 3.009 N/A VAL 126.A N GLU 244.A OE1 no hydrogen 2.824 N/A ASN 127.A ND2 PHE 245.A O no hydrogen 2.761 N/A ASN 127.A ND2 ASP 247.A OD2 no hydrogen 2.663 N/A ASN 128.A N GLY 125.A O no hydrogen 3.042 N/A TYR 130.A N ASN 128.A OD1 no hydrogen 2.858 N/A LEU 134.A N GLN 133.A OE1 no hydrogen 3.037 N/A SER 138.A OG ASP 183.A OD2 no hydrogen 2.525 N/A GLU 141.A N GLU 141.A OE1 no hydrogen 2.711 N/A HIS 142.A N SER 138.A O no hydrogen 2.976 N/A HIS 143.A N ILE 139.A O no hydrogen 3.101 N/A HIS 143.A NE2 ASP 122.A OD1 no hydrogen 2.683 N/A HIS 144.A N MET 140.A O no hydrogen 2.899 N/A HIS 144.A ND1 LEU 121.A O no hydrogen 2.586 N/A PHE 145.A N GLU 141.A O no hydrogen 2.942 N/A ASP 146.A N HIS 142.A O no hydrogen 2.939 N/A GLN 147.A N HIS 143.A O no hydrogen 2.934 N/A CYS 148.A N HIS 144.A O no hydrogen 2.888 N/A CYS 148.A SG SER 118.A OG no hydrogen 3.477 N/A LEU 149.A N PHE 145.A O no hydrogen 2.817 N/A MET 150.A N ASP 146.A O no hydrogen 3.037 N/A ILE 151.A N GLN 147.A O no hydrogen 3.132 N/A LEU 152.A N CYS 148.A O no hydrogen 2.998 N/A ASN 153.A N LEU 149.A O no hydrogen 2.968 N/A ASN 153.A N MET 150.A O no hydrogen 3.319 N/A SER 154.A N ILE 151.A O no hydrogen 3.055 N/A SER 154.A OG MET 150.A O no hydrogen 2.868 N/A ASN 157.A N SER 154.A O no hydrogen 3.019 N/A ASN 157.A ND2 PRO 155.A O no hydrogen 3.110 N/A GLN 158.A NE2 SER 154.A O no hydrogen 3.014 N/A ILE 159.A N ASN 157.A O no hydrogen 2.957 N/A SER 161.A N GLN 158.A O no hydrogen 3.029 N/A SER 161.A OG GLN 158.A O no hydrogen 3.110 N/A LEU 163.A N LEU 160.A O no hydrogen 3.008 N/A SER 164.A N GLU 167.A OE1 no hydrogen 2.950 N/A SER 164.A OG GLU 167.A OE1 no hydrogen 3.294 N/A GLU 167.A N SER 164.A OG no hydrogen 3.175 N/A TYR 168.A N SER 164.A O no hydrogen 2.708 N/A LYS 169.A N ILE 165.A O no hydrogen 2.985 N/A LYS 169.A NZ GLU 166.A OE2 no hydrogen 2.983 N/A THR 170.A N GLU 166.A O no hydrogen 3.160 N/A THR 170.A OG1 GLU 166.A O no hydrogen 3.000 N/A THR 171.A N GLU 167.A O no hydrogen 2.918 N/A THR 171.A OG1 GLU 167.A O no hydrogen 3.304 N/A THR 171.A OG1 TYR 168.A O no hydrogen 2.905 N/A LEU 172.A N TYR 168.A O no hydrogen 2.870 N/A LYS 173.A N LYS 169.A O no hydrogen 3.111 N/A ILE 174.A N THR 170.A O no hydrogen 3.174 N/A ILE 175.A N THR 171.A O no hydrogen 2.820 N/A LYS 176.A N LEU 172.A O no hydrogen 2.800 N/A GLN 177.A N LYS 173.A O no hydrogen 3.009 N/A ALA 178.A N ILE 174.A O no hydrogen 2.821 N/A ILE 179.A N ILE 175.A O no hydrogen 2.939 N/A LEU 180.A N LYS 176.A O no hydrogen 2.853 N/A ALA 181.A N GLN 177.A O no hydrogen 2.822 N/A THR 182.A N ILE 179.A O no hydrogen 3.022 N/A THR 182.A OG1 ILE 179.A O no hydrogen 2.637 N/A ASP 183.A N LEU 180.A O no hydrogen 3.111 N/A ALA 185.A N ASP 183.A OD1 no hydrogen 2.954 N/A TYR 187.A N ASP 183.A O no hydrogen 3.149 N/A TYR 187.A OH ILE 262.A O no hydrogen 2.900 N/A ILE 188.A N LEU 184.A O no hydrogen 2.972 N/A LYS 189.A N ALA 185.A O no hydrogen 3.159 N/A ARG 190.A N LEU 186.A O no hydrogen 3.040 N/A ARG 190.A N TYR 187.A O no hydrogen 3.279 N/A ARG 191.A N TYR 187.A O no hydrogen 2.808 N/A ARG 191.A NH1 ALA 261.A O no hydrogen 2.653 N/A ARG 191.A NH2 ALA 261.A O no hydrogen 3.220 N/A PHE 195.A N ARG 191.A O no hydrogen 3.006 N/A GLU 196.A N GLY 192.A O no hydrogen 2.653 N/A LEU 197.A N GLU 193.A O no hydrogen 2.885 N/A ILE 198.A N PHE 194.A O no hydrogen 3.200 N/A ARG 199.A N PHE 195.A O no hydrogen 2.805 N/A LYS 200.A NZ GLU 196.A OE1 no hydrogen 3.093 N/A ASN 201.A N ILE 198.A O no hydrogen 3.008 N/A GLN 202.A N LEU 197.A O no hydrogen 2.711 N/A ASN 204.A N GLN 210.A OE1 no hydrogen 2.363 N/A GLU 206.A N ASN 204.A OD1 no hydrogen 3.302 N/A HIS 209.A NE2 GLU 193.A OE1 no hydrogen 2.493 N/A GLN 210.A N ASP 207.A O no hydrogen 2.925 N/A GLN 210.A N ASP 207.A OD2 no hydrogen 3.019 N/A LYS 211.A N ASP 207.A O no hydrogen 2.931 N/A LYS 211.A NZ GLU 108.A OE1 no hydrogen 2.851 N/A LYS 211.A NZ GLU 108.A OE2 no hydrogen 2.939 N/A GLU 212.A N PRO 208.A O no hydrogen 3.061 N/A LEU 213.A N HIS 209.A O no hydrogen 3.183 N/A PHE 214.A N GLN 210.A O no hydrogen 2.908 N/A LEU 215.A N LYS 211.A O no hydrogen 2.995 N/A ALA 216.A N GLU 212.A O no hydrogen 3.180 N/A MET 217.A N LEU 213.A O no hydrogen 2.955 N/A LEU 218.A N PHE 214.A O no hydrogen 2.735 N/A MET 219.A N LEU 215.A O no hydrogen 2.976 N/A THR 220.A N ALA 216.A O no hydrogen 3.188 N/A THR 220.A OG1 ALA 216.A O no hydrogen 3.414 N/A ALA 221.A N MET 217.A O no hydrogen 2.956 N/A CYS 222.A N LEU 218.A O no hydrogen 3.086 N/A CYS 222.A SG LEU 218.A O no hydrogen 3.502 N/A ASP 223.A N MET 219.A O no hydrogen 2.867 N/A LEU 224.A N THR 220.A O no hydrogen 2.947 N/A SER 225.A N CYS 222.A O no hydrogen 3.159 N/A SER 225.A OG CYS 222.A O no hydrogen 2.852 N/A ILE 227.A N LEU 224.A O no hydrogen 3.098 N/A THR 228.A N SER 225.A O no hydrogen 3.001 N/A THR 228.A OG1 SER 225.A O no hydrogen 2.617 N/A LYS 229.A N ALA 226.A O no hydrogen 3.150 N/A LYS 229.A NZ PHE 25.A O no hydrogen 2.708 N/A LYS 229.A NZ PHE 27.A O no hydrogen 2.967 N/A GLN 234.A N PRO 230.A O no hydrogen 2.965 N/A GLN 234.A NE2 ALA 226.A O no hydrogen 3.140 N/A GLN 235.A N TRP 231.A O no hydrogen 2.942 N/A ARG 236.A NH1 GLU 239.A OE2 no hydrogen 3.126 N/A ILE 237.A N ILE 233.A O no hydrogen 2.938 N/A ALA 238.A N GLN 234.A O no hydrogen 2.786 N/A GLU 239.A N GLN 235.A O no hydrogen 3.184 N/A LEU 240.A N ARG 236.A O no hydrogen 3.365 N/A VAL 241.A N ILE 237.A O no hydrogen 2.985 N/A ALA 242.A N ALA 238.A O no hydrogen 2.887 N/A THR 243.A N GLU 239.A O no hydrogen 2.949 N/A THR 243.A OG1 GLU 239.A O no hydrogen 3.081 N/A GLU 244.A N LEU 240.A O no hydrogen 2.968 N/A PHE 245.A N VAL 241.A O no hydrogen 2.731 N/A PHE 246.A N ALA 242.A O no hydrogen 3.002 N/A SER 253.A OG LYS 250.A O no hydrogen 3.123 N/A MET 254.A N LYS 250.A O no hydrogen 3.164 N/A GLN 255.A N ILE 251.A O no hydrogen 2.903 N/A GLN 255.A NE2 GLN 234.A OE1 no hydrogen 2.997 N/A VAL 256.A N PRO 252.A O no hydrogen 3.074 N/A GLY 257.A N SER 253.A O no hydrogen 2.983 N/A PHE 258.A N MET 254.A O no hydrogen 2.797 N/A ILE 259.A N GLN 255.A O no hydrogen 2.895 N/A ASP 260.A N VAL 256.A O no hydrogen 2.897 N/A ALA 261.A N GLY 257.A O no hydrogen 2.784 N/A ILE 262.A N PHE 258.A O no hydrogen 2.972 N/A CYS 263.A N PHE 258.A O no hydrogen 3.418 N/A CYS 263.A N ILE 259.A O no hydrogen 3.155 N/A CYS 263.A SG PHE 258.A O no hydrogen 3.863 N/A LEU 264.A N ILE 259.A O no hydrogen 2.853 N/A TYR 267.A N CYS 263.A O no hydrogen 3.089 N/A TYR 267.A OH ALA 221.A O no hydrogen 2.637 N/A GLU 268.A N LEU 264.A O no hydrogen 2.876 N/A ALA 269.A N GLN 265.A O no hydrogen 2.851 N/A LEU 270.A N LEU 266.A O no hydrogen 2.844 N/A THR 271.A N TYR 267.A O no hydrogen 2.927 N/A THR 271.A OG1 TYR 267.A O no hydrogen 3.196 N/A THR 271.A OG1 GLU 268.A O no hydrogen 2.613 N/A HIS 272.A N GLU 268.A O no hydrogen 3.113 N/A VAL 273.A N ALA 269.A O no hydrogen 3.156 N/A SER 274.A N LEU 270.A O no hydrogen 2.892 N/A SER 274.A OG GLY 98.A O no hydrogen 2.676 N/A CYS 277.A N SER 274.A O no hydrogen 2.944 N/A CYS 277.A SG GLY 98.A O no hydrogen 4.012 N/A PHE 278.A N GLU 275.A O no hydrogen 3.108 N/A LEU 280.A N CYS 277.A O no hydrogen 3.023 N/A ASP 282.A N PHE 278.A O no hydrogen 2.775 N/A GLY 283.A N PRO 279.A O no hydrogen 2.901 N/A CYS 284.A N LEU 280.A O no hydrogen 2.955 N/A ARG 285.A N LEU 281.A O no hydrogen 2.996 N/A ARG 285.A NH2 GLU 268.A OE2 no hydrogen 3.375 N/A LYS 286.A N ASP 282.A O no hydrogen 2.975 N/A LYS 286.A NZ ASP 282.A OD2 no hydrogen 2.769 N/A ASN 287.A N GLY 283.A O no hydrogen 3.039 N/A ASN 287.A ND2 ILE 227.A O no hydrogen 2.701 N/A ASN 287.A ND2 LYS 229.A O no hydrogen 2.767 N/A ARG 288.A N CYS 284.A O no hydrogen 3.058 N/A ARG 288.A NH1 ASP 260.A OD2 no hydrogen 2.955 N/A GLN 289.A N ARG 285.A O no hydrogen 3.211 N/A LYS 290.A N LYS 286.A O no hydrogen 3.246 N/A TRP 291.A N ASN 287.A O no hydrogen 2.901 N/A TRP 291.A NE1 GLN 234.A OE1 no hydrogen 2.861 N/A GLN 292.A N ARG 288.A O no hydrogen 2.854 N/A ALA 293.A N GLN 289.A O no hydrogen 3.053 N/A LEU 294.A N LYS 290.A O no hydrogen 3.222 N/A ALA 295.A N TRP 291.A O no hydrogen 2.896 N/A GLU 296.A N ALA 293.A O no hydrogen 3.414 N/A