Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4iov_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): CYS 11.A SG THR 23.A O no hydrogen 3.315 N/A ASP 12.A N THR 23.A O no hydrogen 2.417 N/A SER 13.A N ASP 12.A OD1 no hydrogen 2.891 N/A SER 13.A OG ASP 73.A OD2 no hydrogen 3.116 N/A THR 14.A N THR 21.A O no hydrogen 2.827 N/A TRP 15.A NE1 ASP 73.A OD2 no hydrogen 2.965 N/A LYS 19.A NZ GLU 468.A OE2 no hydrogen 3.018 N/A VAL 20.A N TRP 469.A O no hydrogen 2.873 N/A THR 21.A N THR 14.A O no hydrogen 2.802 N/A THR 22.A N ILE 467.A O no hydrogen 2.862 N/A THR 22.A OG1 ILE 467.A O no hydrogen 3.477 N/A THR 23.A N ASP 12.A O no hydrogen 2.578 N/A SER 24.A N VAL 465.A O no hydrogen 3.024 N/A SER 24.A OG CYS 67.A O no hydrogen 2.960 N/A THR 25.A OG1 HIS 10.A O no hydrogen 2.690 N/A ARG 26.A N VAL 463.A O no hydrogen 3.047 N/A ARG 26.A NE PRO 141.A O no hydrogen 3.022 N/A ARG 26.A NH1 THR 25.A O no hydrogen 2.617 N/A ARG 26.A NH2 PRO 141.A O no hydrogen 3.425 N/A ARG 26.A NH2 PRO 142.A O no hydrogen 2.880 N/A TRP 28.A N GLY 461.A O no hydrogen 2.710 N/A VAL 29.A N PHE 148.A O no hydrogen 2.929 N/A LEU 30.A N SER 459.A O no hydrogen 2.719 N/A TYR 33.A OH VAL 150.A O no hydrogen 2.518 N/A HIS 36.A N TYR 33.A O no hydrogen 2.870 N/A LEU 37.A N ASN 34.A O no hydrogen 2.815 N/A LEU 39.A N SER 54.A O no hydrogen 3.193 N/A LEU 41.A N GLY 52.A O no hydrogen 2.541 N/A THR 43.A N TYR 50.A O no hydrogen 3.295 N/A THR 44.A OG1 THR 44.A O no hydrogen 2.231 N/A ASN 48.A N SER 45.A O no hydrogen 3.139 N/A TYR 50.A N THR 43.A O no hydrogen 3.262 N/A ASN 51.A ND2 ILE 158.A O no hydrogen 3.069 N/A ASN 51.A ND2 ASN 170.A OD1 no hydrogen 3.677 N/A GLY 52.A N LEU 41.A O no hydrogen 2.678 N/A PHE 53.A N TYR 155.A O no hydrogen 3.013 N/A SER 54.A N LEU 39.A O no hydrogen 3.090 N/A SER 54.A OG ASN 34.A OD1 no hydrogen 2.614 N/A THR 55.A N TYR 153.A O no hydrogen 2.737 N/A TRP 57.A NE1 GLU 176.A OE1 no hydrogen 2.586 N/A GLY 58.A N ILE 433.A O no hydrogen 2.714 N/A TYR 59.A N PRO 151.A O no hydrogen 3.039 N/A PHE 60.A N ILE 431.A O no hydrogen 3.120 N/A ASN 63.A N ASP 61.A OD1 no hydrogen 2.784 N/A ASN 63.A ND2 MET 132.A O no hydrogen 3.397 N/A ASN 63.A ND2 TRP 403.A O no hydrogen 2.996 N/A PHE 65.A N GLY 400.A O no hydrogen 3.059 N/A HIS 66.A ND1 GLU 507.A OE2 no hydrogen 3.309 N/A CYS 67.A N ARG 64.A O no hydrogen 3.266 N/A CYS 67.A SG ARG 64.A O no hydrogen 3.024 N/A CYS 67.A SG LEU 140.A O no hydrogen 3.456 N/A HIS 68.A N PHE 65.A O no hydrogen 2.858 N/A HIS 68.A NE2 PHE 62.A O no hydrogen 3.027 N/A SER 70.A OG ASP 73.A OD1 no hydrogen 2.729 N/A ASP 73.A N SER 70.A OG no hydrogen 3.166 N/A TRP 74.A N SER 70.A O no hydrogen 2.903 N/A TRP 74.A NE1 GLY 512.A O no hydrogen 3.096 N/A GLN 75.A N PRO 71.A O no hydrogen 2.851 N/A ARG 76.A N ARG 72.A O no hydrogen 2.780 N/A ARG 76.A NH1 ASP 73.A OD2 no hydrogen 3.264 N/A LEU 77.A N ASP 73.A O no hydrogen 2.846 N/A ILE 78.A N TRP 74.A O no hydrogen 2.977 N/A ASN 79.A N GLN 75.A O no hydrogen 2.989 N/A ASN 79.A ND2 PHE 485.A O no hydrogen 3.319 N/A ASN 81.A N LEU 77.A O no hydrogen 3.143 N/A TRP 82.A N GLU 472.A O no hydrogen 2.971 N/A LEU 84.A N HIS 201.A O no hydrogen 3.356 N/A ARG 85.A N GLU 470.A O no hydrogen 3.005 N/A ARG 85.A NH1 VAL 198.A O no hydrogen 2.882 N/A ARG 85.A NH2 GLU 470.A OE2 no hydrogen 3.121 N/A LYS 87.A N GLU 468.A O no hydrogen 2.795 N/A LYS 87.A NZ GLU 468.A OE2 no hydrogen 2.768 N/A ALA 88.A N GLU 468.A O no hydrogen 3.226 N/A MET 89.A N TYR 193.A O no hydrogen 2.771 N/A ARG 90.A N GLN 466.A O no hydrogen 2.978 N/A VAL 91.A N MET 191.A O no hydrogen 2.861 N/A LYS 92.A N ALA 464.A O no hydrogen 2.919 N/A ILE 93.A N PHE 189.A O no hydrogen 2.881 N/A PHE 94.A N GLN 462.A O no hydrogen 2.817 N/A ASN 95.A N SER 6.A OG no hydrogen 2.925 N/A ASN 95.A ND2 SER 6.A OG no hydrogen 3.097 N/A GLN 97.A N THR 460.A O no hydrogen 2.833 N/A GLN 97.A NE2 ASN 95.A O no hydrogen 3.645 N/A LYS 99.A N TYR 458.A O no hydrogen 2.787 N/A GLU 100.A N ALA 111.A O no hydrogen 2.840 N/A VAL 101.A N THR 456.A O no hydrogen 3.006 N/A THR 102.A N THR 109.A O no hydrogen 2.587 N/A SER 104.A OG GLU 107.A O no hydrogen 2.504 N/A ALA 111.A N GLU 100.A O no hydrogen 2.952 N/A ASN 113.A N VAL 98.A O no hydrogen 3.266 N/A ASN 113.A ND2 GLN 457.A OE1 no hydrogen 2.738 N/A SER 116.A N LEU 114.A O no hydrogen 3.039 N/A SER 116.A OG GLN 457.A OE1 no hydrogen 3.082 N/A VAL 118.A N LEU 183.A O no hydrogen 3.051 N/A GLN 119.A N LYS 434.A O no hydrogen 2.888 N/A GLN 119.A NE2 THR 436.A OG1 no hydrogen 2.337 N/A ILE 120.A N GLN 181.A O no hydrogen 2.835 N/A PHE 121.A N PHE 432.A O no hydrogen 3.214 N/A SER 125.A OG GLU 127.A OE1 no hydrogen 3.485 N/A TYR 126.A OH PRO 427.A O no hydrogen 2.462 N/A GLU 127.A N ASP 123.A OD1 no hydrogen 3.306 N/A TYR 130.A OH PRO 428.A O no hydrogen 2.643 N/A ALA 134.A N VAL 131.A O no hydrogen 3.354 N/A SER 139.A OG ASP 61.A OD2 no hydrogen 2.734 N/A LEU 140.A N ASP 61.A O no hydrogen 3.105 N/A PHE 148.A N THR 27.A O no hydrogen 3.202 N/A VAL 150.A N VAL 29.A O no hydrogen 3.063 N/A GLN 152.A NE2 ASN 34.A OD1 no hydrogen 2.942 N/A GLN 152.A NE2 THR 55.A O no hydrogen 2.801 N/A TYR 153.A N TRP 57.A O no hydrogen 2.799 N/A TYR 153.A OH PRO 129.A O no hydrogen 2.821 N/A TYR 155.A N PHE 53.A O no hydrogen 2.963 N/A TYR 155.A OH TYR 173.A O no hydrogen 2.771 N/A GLY 157.A N ASN 51.A O no hydrogen 2.720 N/A GLN 164.A NE2 GLN 166.A OE1 no hydrogen 3.558 N/A ASN 170.A N THR 167.A O no hydrogen 3.044 N/A ASN 170.A ND2 THR 167.A O no hydrogen 3.458 N/A TYR 173.A N TYR 155.A OH no hydrogen 2.789 N/A CYS 174.A SG TYR 38.A OH no hydrogen 3.883 N/A TYR 177.A N CYS 174.A O no hydrogen 2.789 N/A PHE 178.A N LEU 175.A O no hydrogen 3.180 N/A GLN 181.A N ILE 120.A O no hydrogen 2.962 N/A GLN 181.A NE2 ASN 188.A O no hydrogen 2.996 N/A LEU 183.A N VAL 118.A O no hydrogen 2.890 N/A THR 185.A OG1 ILE 96.A O no hydrogen 3.490 N/A ASN 187.A N ARG 184.A O no hydrogen 2.842 N/A ASN 187.A ND2 ARG 184.A O no hydrogen 3.464 N/A PHE 189.A N ILE 93.A O no hydrogen 3.048 N/A MET 191.A N VAL 91.A O no hydrogen 2.892 N/A TYR 193.A N MET 89.A O no hydrogen 2.730 N/A TYR 193.A OH HIS 426.A O no hydrogen 2.366 N/A PHE 195.A N LYS 87.A O no hydrogen 2.755 N/A HIS 201.A N LEU 84.A O no hydrogen 2.686 N/A HIS 201.A NE2 ASP 395.A OD1 no hydrogen 3.298 N/A MET 203.A N TRP 82.A O no hydrogen 2.508 N/A ALA 205.A N LEU 516.A O no hydrogen 2.797 N/A SER 207.A N ASN 518.A O no hydrogen 2.809 N/A SER 209.A OG ASP 211.A OD2 no hydrogen 3.411 N/A LEU 210.A N ALA 352.A O no hydrogen 3.039 N/A ARG 212.A N SER 209.A O no hydrogen 2.960 N/A LEU 217.A N ASN 215.A OD1 no hydrogen 2.972 N/A LEU 218.A N ASN 215.A O no hydrogen 3.134 N/A GLN 220.A NE2 ARG 255.A O no hydrogen 2.828 N/A HIS 224.A N GLY 244.A O no hydrogen 3.165 N/A GLN 226.A N THR 242.A O no hydrogen 2.916 N/A THR 229.A OG1 SER 230.A O no hydrogen 3.024 N/A THR 229.A OG1 GLN 236.A O no hydrogen 3.482 N/A THR 233.A OG1 GLN 236.A O no hydrogen 3.383 N/A ASN 238.A N SER 230.A OG no hydrogen 2.812 N/A THR 242.A N SER 227.A O no hydrogen 2.931 N/A THR 242.A OG1 SER 227.A O no hydrogen 3.311 N/A GLY 244.A N HIS 224.A O no hydrogen 2.973 N/A LYS 245.A NZ ASP 219.A OD2 no hydrogen 3.206 N/A ILE 246.A N LEU 222.A O no hydrogen 3.001 N/A SER 248.A OG PRO 216.A O no hydrogen 3.150 N/A ASP 250.A N ARG 247.A O no hydrogen 3.192 N/A PHE 253.A N ASP 250.A O no hydrogen 3.133 N/A TYR 254.A N PHE 251.A O no hydrogen 2.727 N/A TYR 254.A OH LEU 218.A O no hydrogen 3.026 N/A ARG 255.A N GLN 220.A OE1 no hydrogen 2.741 N/A ARG 255.A NH1 PHE 253.A O no hydrogen 2.629 N/A LYS 256.A NZ ASP 211.A O no hydrogen 3.312 N/A LYS 256.A NZ PHE 251.A O no hydrogen 3.346 N/A LYS 256.A NZ TYR 254.A O no hydrogen 3.289 N/A LEU 259.A N GLY 388.A O no hydrogen 2.748 N/A CYS 263.A N MET 383.A O no hydrogen 2.946 N/A CYS 263.A SG THR 381.A O no hydrogen 3.180 N/A LYS 265.A N THR 381.A O no hydrogen 3.244 N/A GLN 266.A N ASP 357.A O no hydrogen 2.947 N/A GLN 267.A NE2 ARG 268.A O no hydrogen 3.551 N/A PHE 269.A N PHE 319.A O no hydrogen 3.073 N/A SER 270.A N ASN 276.A OD1 no hydrogen 2.712 N/A SER 270.A OG THR 272.A OG1 no hydrogen 2.834 N/A LYS 271.A N GLY 317.A O no hydrogen 2.508 N/A LYS 271.A NZ PRO 314.A O no hydrogen 2.678 N/A LYS 271.A NZ ASP 316.A O no hydrogen 3.244 N/A THR 272.A N SER 270.A OG no hydrogen 3.140 N/A THR 272.A OG1 SER 270.A OG no hydrogen 2.834 N/A GLN 275.A N THR 272.A O no hydrogen 3.113 N/A ASN 276.A N ALA 273.A O no hydrogen 3.368 N/A ASN 276.A ND2 SER 270.A O no hydrogen 3.277 N/A ALA 286.A N GLY 283.A O no hydrogen 2.979 N/A LEU 287.A N PRO 280.A O no hydrogen 2.746 N/A LYS 289.A N ALA 286.A O no hydrogen 3.070 N/A LYS 289.A NZ GLY 284.A O no hydrogen 3.230 N/A LYS 289.A NZ ASN 285.A OD1 no hydrogen 3.103 N/A TYR 290.A N LEU 287.A O no hydrogen 2.609 N/A TYR 290.A OH ASN 285.A OD1 no hydrogen 2.777 N/A ASP 291.A N LEU 287.A O no hydrogen 3.245 N/A ASP 291.A N LEU 288.A O no hydrogen 3.324 N/A THR 292.A OG1 LYS 265.A O no hydrogen 2.933 N/A HIS 293.A ND1 ASP 291.A O no hydrogen 3.024 N/A TYR 294.A N SER 301.A O no hydrogen 2.983 N/A LEU 296.A N ARG 299.A O no hydrogen 3.108 N/A ARG 299.A N LEU 296.A O no hydrogen 2.763 N/A SER 301.A N TYR 294.A O no hydrogen 3.376 N/A ALA 310.A N PRO 355.A O no hydrogen 2.768 N/A THR 311.A OG1 ALA 312.A O no hydrogen 3.072 N/A SER 315.A OG ASP 316.A OD1 no hydrogen 3.437 N/A PHE 319.A N PHE 269.A O no hydrogen 2.834 N/A ALA 322.A N SER 320.A OG no hydrogen 2.839 N/A GLN 323.A N SER 320.A O no hydrogen 3.271 N/A LEU 324.A N THR 345.A OG1 no hydrogen 2.768 N/A PHE 326.A N LEU 343.A O no hydrogen 2.842 N/A SER 330.A OG ASN 341.A OD1 no hydrogen 3.170 N/A THR 336.A OG1 SER 338.A O no hydrogen 3.536 N/A ASN 340.A N SER 338.A OG no hydrogen 3.102 N/A ASN 341.A N SER 338.A O no hydrogen 3.315 N/A LEU 342.A N ALA 339.A O no hydrogen 3.387 N/A LEU 343.A N PHE 326.A O no hydrogen 2.700 N/A THR 345.A N LEU 324.A O no hydrogen 2.994 N/A THR 345.A OG1 LEU 324.A O no hydrogen 3.028 N/A GLU 347.A N THR 311.A OG1 no hydrogen 3.049 N/A GLU 348.A N SER 346.A OG no hydrogen 3.420 N/A ILE 350.A N GLU 347.A O no hydrogen 3.130 N/A ALA 351.A N GLU 348.A O no hydrogen 2.756 N/A THR 353.A N ILE 350.A O no hydrogen 2.787 N/A THR 353.A OG1 VAL 390.A O no hydrogen 3.545 N/A ASN 354.A N ILE 350.A O no hydrogen 3.230 N/A ASN 354.A ND2 GLN 392.A O no hydrogen 3.471 N/A ARG 356.A NH1 ASP 357.A OD1 no hydrogen 2.897 N/A ASP 357.A N ALA 310.A O no hydrogen 2.736 N/A THR 358.A N ASP 357.A OD1 no hydrogen 2.630 N/A MET 360.A N ASP 359.A OD1 no hydrogen 2.269 N/A PHE 361.A N VAL 380.A O no hydrogen 3.184 N/A ILE 364.A N GLY 378.A O no hydrogen 2.949 N/A ASP 366.A N ILE 376.A O no hydrogen 2.977 N/A ASN 370.A N THR 373.A O no hydrogen 3.052 N/A ASN 370.A ND2 THR 373.A OG1 no hydrogen 3.413 N/A THR 373.A N ASN 370.A O no hydrogen 2.742 N/A GLY 378.A N ILE 364.A O no hydrogen 2.691 N/A VAL 380.A N GLY 362.A O no hydrogen 3.149 N/A MET 383.A N CYS 263.A O no hydrogen 2.766 N/A MET 389.A N LEU 386.A O no hydrogen 3.109 N/A VAL 390.A N LEU 259.A O no hydrogen 3.137 N/A GLN 392.A NE2 TRP 391.A O no hydrogen 3.686 N/A ARG 394.A NE LEU 418.A O no hydrogen 2.695 N/A ARG 394.A NH2 GLY 306.A O no hydrogen 2.946 N/A ASP 395.A N GLU 347.A OE1 no hydrogen 3.509 N/A ILE 396.A N ASP 395.A OD1 no hydrogen 2.324 N/A TYR 397.A OH GLU 347.A OE1 no hydrogen 3.323 N/A TYR 397.A OH GLU 347.A OE2 no hydrogen 2.743 N/A TYR 398.A N ILE 511.A O no hydrogen 2.649 N/A TYR 398.A OH PHE 69.A O no hydrogen 2.573 N/A GLN 399.A N GLN 399.A OE1 no hydrogen 2.656 N/A GLN 399.A NE2 GLU 507.A OE1 no hydrogen 3.424 N/A GLN 399.A NE2 ARG 509.A O no hydrogen 3.355 N/A GLY 400.A N TYR 397.A O no hydrogen 2.490 N/A ILE 402.A N ASN 63.A O no hydrogen 2.743 N/A ILE 402.A N ASN 63.A OD1 no hydrogen 3.410 N/A TRP 403.A N ASN 63.A OD1 no hydrogen 3.085 N/A TRP 403.A NE1 TYR 130.A OH no hydrogen 2.994 N/A ALA 404.A N PHE 422.A O no hydrogen 3.174 N/A ILE 406.A N LEU 424.A O no hydrogen 2.782 N/A SER 416.A OG PRO 415.A O no hydrogen 3.124 N/A GLY 420.A N PRO 417.A O no hydrogen 3.385 N/A PHE 422.A N ILE 402.A O no hydrogen 2.746 N/A LEU 424.A N ALA 404.A O no hydrogen 3.142 N/A LYS 425.A N GLU 196.A OE2 no hydrogen 2.737 N/A HIS 426.A N GLU 196.A OE2 no hydrogen 3.355 N/A PHE 432.A N PHE 121.A O no hydrogen 2.937 N/A ILE 433.A N GLY 58.A O no hydrogen 2.701 N/A LYS 434.A N GLN 119.A O no hydrogen 3.209 N/A LYS 434.A NZ GLU 176.A OE2 no hydrogen 2.924 N/A THR 436.A N THR 117.A O no hydrogen 2.905 N/A THR 436.A OG1 THR 117.A O no hydrogen 2.754 N/A THR 436.A OG1 THR 117.A OG1 no hydrogen 2.378 N/A ALA 440.A N SER 453.A O no hydrogen 2.876 N/A ILE 455.A N VAL 438.A O no hydrogen 3.312 N/A GLN 457.A NE2 SER 116.A OG no hydrogen 3.299 N/A TYR 458.A N LYS 99.A O no hydrogen 3.113 N/A SER 459.A N LEU 30.A O no hydrogen 3.025 N/A SER 459.A OG ASN 435.A OD1 no hydrogen 2.681 N/A THR 460.A N GLN 97.A O no hydrogen 2.979 N/A THR 460.A OG1 TRP 28.A O no hydrogen 2.734 N/A GLY 461.A N TRP 28.A O no hydrogen 3.248 N/A GLN 462.A N PHE 94.A O no hydrogen 2.961 N/A GLN 462.A NE2 ASN 95.A OD1 no hydrogen 3.134 N/A VAL 463.A N ARG 26.A O no hydrogen 3.002 N/A ALA 464.A N LYS 92.A O no hydrogen 2.773 N/A VAL 465.A N SER 24.A O no hydrogen 2.984 N/A GLN 466.A N ARG 90.A O no hydrogen 2.871 N/A ILE 467.A N THR 22.A O no hydrogen 2.844 N/A GLU 468.A N ALA 88.A O no hydrogen 2.724 N/A TRP 469.A N VAL 20.A O no hydrogen 2.818 N/A TRP 469.A NE1 THR 22.A OG1 no hydrogen 3.066 N/A GLU 470.A N ARG 85.A O no hydrogen 2.904 N/A ILE 471.A N GLY 18.A O no hydrogen 2.968 N/A GLU 472.A N GLY 83.A O no hydrogen 2.978 N/A SER 476.A N GLU 474.A OE1 no hydrogen 3.301 N/A ARG 478.A N SER 476.A OG no hydrogen 3.103 N/A ARG 478.A NE ASN 480.A O no hydrogen 2.773 N/A ARG 478.A NH2 PRO 481.A O no hydrogen 2.849 N/A GLN 484.A NE2 ASN 79.A O no hydrogen 3.096 N/A TRP 497.A NE1 TYR 489.A OH no hydrogen 2.992 N/A ASP 500.A N LYS 504.A O no hydrogen 3.137 N/A GLY 503.A N ASP 500.A OD1 no hydrogen 2.588 N/A LYS 504.A N ASP 500.A OD1 no hydrogen 3.376 N/A ILE 511.A N GLN 399.A OE1 no hydrogen 3.265 N/A SER 513.A N ASP 395.A OD2 no hydrogen 2.964 N/A SER 513.A OG ASP 395.A OD1 no hydrogen 2.958 N/A ARG 514.A N ASP 395.A OD2 no hydrogen 3.104 N/A ARG 514.A NE SER 202.A O no hydrogen 3.431 N/A ARG 514.A NH1 ASN 393.A O no hydrogen 3.143 N/A ARG 514.A NH2 SER 202.A OG no hydrogen 3.232 N/A ARG 514.A NH2 ASN 393.A O no hydrogen 2.648 N/A THR 517.A N GLU 482.A OE1 no hydrogen 3.214 N/A THR 517.A OG1 ALA 205.A O no hydrogen 3.212 N/A ASN 518.A N ALA 205.A O no hydrogen 3.082 N/A HIS 519.A ND1 LEU 520.A OXT no hydrogen 2.526 N/A LEU 520.A N GLN 208.A OE1 no hydrogen 3.239 N/A