Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4j0x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 4.A N TYR 284.A O no hydrogen 2.917 N/A ARG 5.A N TYR 284.A O no hydrogen 2.970 N/A ARG 5.A NH1 GLU 329.A OE1 no hydrogen 3.386 N/A ARG 5.A NH2 GLU 329.A OE1 no hydrogen 3.427 N/A ARG 5.A NH2 GLU 329.A OE2 no hydrogen 3.176 N/A TYR 6.A OH VAL 3.A O no hydrogen 3.399 N/A GLY 8.A N ASN 286.A OD1 no hydrogen 3.314 N/A LYS 10.A N PHE 7.A O no hydrogen 3.071 N/A LEU 11.A N GLY 8.A O no hydrogen 3.470 N/A LEU 12.A N ASP 364.A O no hydrogen 2.859 N/A ALA 16.A N ILE 13.A O no hydrogen 2.934 N/A LYS 17.A N VAL 362.A O no hydrogen 2.931 N/A LYS 17.A NZ GLN 18.A O no hydrogen 3.030 N/A SER 19.A N SER 360.A O no hydrogen 2.914 N/A THR 21.A N ILE 358.A O no hydrogen 2.914 N/A VAL 23.A N ASN 356.A O no hydrogen 3.296 N/A ASN 26.A ND2 ASP 46.A OD1 no hydrogen 3.546 N/A ASN 27.A N ASN 356.A OD1 no hydrogen 3.130 N/A THR 29.A N VAL 43.A O no hydrogen 2.915 N/A THR 29.A OG1 VAL 43.A O no hydrogen 3.474 N/A THR 29.A OG1 ILE 85.A O no hydrogen 2.680 N/A CYS 30.A SG ILE 31.A O no hydrogen 3.879 N/A CYS 30.A SG VAL 88.A O no hydrogen 3.618 N/A SER 32.A N TYR 41.A O no hydrogen 2.803 N/A CYS 33.A N GLN 326.A OE1 no hydrogen 3.181 N/A PHE 34.A N PHE 39.A O no hydrogen 2.687 N/A ARG 37.A NE ASP 53.A OD2 no hydrogen 3.411 N/A PHE 39.A N PHE 34.A O no hydrogen 3.336 N/A ALA 40.A N TYR 52.A O no hydrogen 2.939 N/A TYR 41.A N SER 32.A O no hydrogen 2.642 N/A THR 42.A N THR 50.A O no hydrogen 2.911 N/A VAL 43.A N CYS 30.A O no hydrogen 3.253 N/A LYS 45.A N ASN 27.A O no hydrogen 3.154 N/A LYS 45.A NZ GLU 341.A OE1 no hydrogen 2.804 N/A LYS 45.A NZ HIS 342.A O no hydrogen 2.837 N/A LEU 47.A N SER 44.A O no hydrogen 3.004 N/A GLN 48.A N SER 44.A OG no hydrogen 3.286 N/A GLN 48.A NE2 THR 50.A OG1 no hydrogen 3.106 N/A LEU 49.A N ALA 67.A O no hydrogen 2.886 N/A THR 50.A N THR 42.A O no hydrogen 2.903 N/A THR 50.A OG1 GLU 25.A OE2 no hydrogen 3.374 N/A LYS 51.A N LYS 65.A O no hydrogen 2.884 N/A LYS 51.A NZ THR 111.A O no hydrogen 2.927 N/A TYR 52.A N ALA 40.A O no hydrogen 2.859 N/A ASP 53.A N LYS 62.A O no hydrogen 2.727 N/A ILE 54.A N LEU 38.A O no hydrogen 3.072 N/A THR 55.A N ASP 53.A OD1 no hydrogen 2.964 N/A SER 58.A N ASP 56.A OD1 no hydrogen 3.146 N/A LYS 59.A N ASP 56.A O no hydrogen 3.251 N/A LYS 62.A N ASP 53.A O no hydrogen 2.749 N/A LEU 64.A N LYS 51.A O no hydrogen 2.862 N/A LYS 65.A NZ SER 113.A O no hydrogen 3.359 N/A ALA 67.A N LEU 49.A O no hydrogen 2.898 N/A GLY 69.A N LEU 47.A O no hydrogen 2.963 N/A TYR 73.A N GLY 70.A O no hydrogen 2.751 N/A ILE 74.A N ALA 71.A O no hydrogen 3.137 N/A ASN 76.A ND2 ASP 103.A O no hydrogen 2.519 N/A ASN 76.A ND2 ARG 104.A O no hydrogen 3.089 N/A THR 78.A OG1 TYR 73.A O no hydrogen 2.699 N/A HIS 81.A ND1 ASP 103.A OD2 no hydrogen 3.237 N/A HIS 81.A NE2 THR 99.A OG1 no hydrogen 2.503 N/A TYR 82.A N ASP 103.A OD2 no hydrogen 2.954 N/A ASP 83.A N ASP 103.A OD2 no hydrogen 3.102 N/A GLU 84.A N ASP 83.A OD1 no hydrogen 2.659 N/A LEU 86.A N GLY 100.A O no hydrogen 2.898 N/A THR 87.A N GLY 100.A O no hydrogen 3.139 N/A ALA 89.A N VAL 98.A O no hydrogen 3.002 N/A ALA 90.A N SER 32.A OG no hydrogen 2.676 N/A SER 91.A N TYR 96.A O no hydrogen 2.700 N/A SER 91.A OG TYR 96.A O no hydrogen 2.872 N/A GLY 94.A N SER 91.A O no hydrogen 3.102 N/A LYS 95.A NZ TYR 96.A OH no hydrogen 3.484 N/A TYR 96.A N SER 91.A OG no hydrogen 2.752 N/A VAL 97.A N TRP 109.A O no hydrogen 2.934 N/A VAL 98.A N ALA 89.A O no hydrogen 2.956 N/A THR 99.A N ILE 107.A O no hydrogen 2.877 N/A THR 99.A OG1 HIS 81.A NE2 no hydrogen 2.503 N/A THR 99.A OG1 ILE 107.A O no hydrogen 3.452 N/A GLY 100.A N THR 87.A O no hydrogen 3.185 N/A ARG 102.A N GLU 84.A O no hydrogen 2.911 N/A ARG 102.A NH1 GLU 84.A OE2 no hydrogen 2.994 N/A ARG 102.A NH2 LEU 344.A O no hydrogen 3.262 N/A ARG 104.A N GLY 101.A O no hydrogen 3.277 N/A LYS 105.A NZ THR 78.A O no hydrogen 3.151 N/A LYS 105.A NZ THR 78.A OG1 no hydrogen 3.218 N/A LYS 105.A NZ GLY 80.A O no hydrogen 2.338 N/A LEU 106.A N ILE 120.A O no hydrogen 2.910 N/A ILE 107.A N THR 99.A O no hydrogen 2.905 N/A VAL 108.A N LYS 118.A O no hydrogen 2.849 N/A TRP 109.A N VAL 97.A O no hydrogen 2.864 N/A TRP 109.A NE1 THR 99.A OG1 no hydrogen 2.975 N/A SER 110.A N SER 115.A O no hydrogen 2.886 N/A THR 111.A N LYS 95.A O no hydrogen 3.099 N/A THR 111.A OG1 GLY 94.A O no hydrogen 2.602 N/A THR 111.A OG1 LYS 95.A O no hydrogen 3.440 N/A GLU 112.A N SER 110.A OG no hydrogen 3.425 N/A SER 113.A OG SER 115.A OG no hydrogen 2.425 N/A SER 115.A OG SER 113.A OG no hydrogen 2.425 N/A VAL 117.A N VAL 108.A O no hydrogen 2.695 N/A LYS 118.A N VAL 108.A O no hydrogen 3.021 N/A ILE 120.A N LEU 106.A O no hydrogen 2.870 N/A THR 122.A N ARG 104.A O no hydrogen 3.272 N/A THR 122.A OG1 ARG 104.A O no hydrogen 3.301 N/A THR 122.A OG1 GLY 127.A O no hydrogen 3.019 N/A ARG 126.A N ASP 124.A OD1 no hydrogen 2.777 N/A GLY 127.A N ASP 124.A O no hydrogen 3.124 N/A GLU 128.A N ARG 126.A O no hydrogen 2.931 N/A VAL 129.A N GLY 101.A O no hydrogen 3.023 N/A LEU 130.A N SER 144.A O no hydrogen 2.904 N/A SER 131.A N SER 144.A O no hydrogen 3.347 N/A SER 131.A OG ASP 173.A OD1 no hydrogen 3.055 N/A ALA 133.A N TYR 142.A O no hydrogen 2.992 N/A ARG 135.A N GLN 140.A O no hydrogen 2.880 N/A ARG 135.A NE ALA 178.A O no hydrogen 2.477 N/A ARG 135.A NH1 GLN 140.A OE1 no hydrogen 2.655 N/A ARG 135.A NH2 ALA 178.A O no hydrogen 3.162 N/A LYS 136.A N LEU 177.A O no hydrogen 2.492 N/A LYS 136.A NZ ALA 176.A O no hydrogen 2.700 N/A SER 138.A OG GLN 140.A OE1 no hydrogen 3.492 N/A GLN 140.A N SER 138.A OG no hydrogen 2.712 N/A LEU 141.A N TYR 153.A O no hydrogen 2.912 N/A TYR 142.A N ALA 133.A O no hydrogen 2.975 N/A ALA 143.A N ARG 151.A O no hydrogen 2.881 N/A SER 144.A N SER 131.A O no hydrogen 2.907 N/A SER 144.A OG SER 131.A O no hydrogen 3.539 N/A SER 144.A OG VAL 171.A O no hydrogen 3.032 N/A CYS 145.A N LYS 149.A O no hydrogen 3.077 N/A CYS 145.A SG ALA 143.A O no hydrogen 3.626 N/A ALA 146.A N GLU 128.A O no hydrogen 2.925 N/A LYS 149.A NZ ASP 147.A O no hydrogen 2.982 N/A ILE 150.A N LEU 164.A O no hydrogen 2.965 N/A ARG 151.A N ALA 143.A O no hydrogen 2.886 N/A ARG 151.A NH1 ASP 147.A OD1 no hydrogen 3.224 N/A ARG 151.A NH1 ASP 147.A OD2 no hydrogen 3.456 N/A ARG 151.A NH2 ASP 147.A OD2 no hydrogen 2.912 N/A THR 152.A N GLU 162.A O no hydrogen 2.943 N/A TYR 153.A N LEU 141.A O no hydrogen 2.884 N/A SER 154.A N SER 159.A O no hydrogen 3.259 N/A SER 154.A OG ASP 139.A OD2 no hydrogen 3.404 N/A ILE 155.A N ASP 139.A O no hydrogen 2.979 N/A ASN 156.A N ASP 139.A OD2 no hydrogen 2.712 N/A GLN 157.A N SER 154.A O no hydrogen 3.170 N/A PHE 158.A N ILE 155.A O no hydrogen 3.159 N/A SER 159.A N SER 154.A O no hydrogen 3.277 N/A SER 159.A OG GLN 157.A OE1 no hydrogen 3.518 N/A LEU 161.A N THR 152.A O no hydrogen 2.937 N/A GLU 162.A N THR 152.A OG1 no hydrogen 3.239 N/A LEU 164.A N ILE 150.A O no hydrogen 2.818 N/A HIS 167.A ND1 ASP 189.A OD2 no hydrogen 2.746 N/A HIS 167.A NE2 THR 184.A OG1 no hydrogen 2.605 N/A HIS 168.A N ASP 189.A OD2 no hydrogen 3.403 N/A VAL 171.A N CYS 145.A O no hydrogen 3.308 N/A GLU 172.A N VAL 185.A O no hydrogen 3.044 N/A ILE 174.A N ASP 173.A OD1 no hydrogen 2.895 N/A SER 175.A N VAL 183.A O no hydrogen 2.885 N/A ARG 181.A NH1 ASP 236.A O no hydrogen 3.501 N/A CYS 182.A N TRP 195.A O no hydrogen 2.997 N/A VAL 183.A N SER 175.A O no hydrogen 2.887 N/A THR 184.A N MET 193.A O no hydrogen 2.928 N/A THR 184.A OG1 HIS 167.A NE2 no hydrogen 2.605 N/A THR 184.A OG1 MET 193.A O no hydrogen 3.427 N/A VAL 185.A N ASP 173.A O no hydrogen 2.944 N/A GLY 186.A N THR 191.A O no hydrogen 3.165 N/A ALA 187.A N ILE 228.A O no hydrogen 3.121 N/A ARG 188.A N ASP 169.A OD2 no hydrogen 3.051 N/A ASP 189.A N GLY 186.A O no hydrogen 3.215 N/A ARG 190.A N ALA 187.A O no hydrogen 3.067 N/A THR 191.A N ASP 189.A OD1 no hydrogen 2.781 N/A THR 191.A OG1 ASP 189.A OD1 no hydrogen 3.014 N/A THR 191.A OG1 ASP 189.A OD2 no hydrogen 3.043 N/A ALA 192.A N PHE 205.A O no hydrogen 2.885 N/A MET 193.A N THR 184.A O no hydrogen 2.894 N/A LEU 194.A N LEU 203.A O no hydrogen 2.919 N/A TRP 195.A N CYS 182.A O no hydrogen 2.832 N/A TRP 195.A NE1 THR 184.A OG1 no hydrogen 2.812 N/A LYS 196.A N THR 201.A O no hydrogen 3.161 N/A ASP 199.A N LYS 196.A O no hydrogen 3.126 N/A GLU 200.A N ILE 197.A O no hydrogen 3.373 N/A LEU 203.A N LEU 194.A O no hydrogen 2.878 N/A PHE 205.A N ALA 192.A O no hydrogen 2.871 N/A GLY 207.A N ARG 190.A O no hydrogen 2.800 N/A GLY 208.A N GLU 225.A OE1 no hydrogen 2.684 N/A LEU 214.A N GLU 210.A O no hydrogen 2.875 N/A LEU 215.A N PRO 211.A O no hydrogen 2.877 N/A ARG 216.A N GLN 212.A O no hydrogen 2.918 N/A ARG 217.A N LYS 213.A O no hydrogen 2.928 N/A TRP 218.A N LEU 215.A O no hydrogen 3.075 N/A MET 219.A N LEU 215.A O no hydrogen 3.035 N/A GLU 221.A N TRP 218.A O no hydrogen 3.360 N/A GLY 226.A N ASP 244.A OD1 no hydrogen 3.298 N/A SER 227.A N ASP 244.A OD1 no hydrogen 3.019 N/A SER 227.A OG ASP 229.A OD1 no hydrogen 2.355 N/A ILE 228.A N ALA 187.A O no hydrogen 2.899 N/A ASP 229.A N GLY 242.A O no hydrogen 2.803 N/A VAL 230.A N GLY 242.A O no hydrogen 2.973 N/A VAL 231.A N ASP 173.A OD2 no hydrogen 3.070 N/A SER 232.A N ILE 240.A O no hydrogen 2.921 N/A MET 233.A N SER 175.A OG no hydrogen 3.238 N/A VAL 234.A N HIS 238.A O no hydrogen 3.273 N/A ASP 236.A N GLY 1.A O no hydrogen 3.385 N/A PHE 237.A N ASP 235.A OD1 no hydrogen 2.780 N/A HIS 238.A ND1 ASP 235.A OD1 no hydrogen 2.886 N/A HIS 238.A ND1 ASP 235.A OD2 no hydrogen 3.227 N/A PHE 239.A N TRP 251.A O no hydrogen 2.974 N/A ILE 240.A N SER 232.A O no hydrogen 2.860 N/A THR 241.A N CYS 249.A O no hydrogen 2.903 N/A GLY 242.A N VAL 230.A O no hydrogen 2.902 N/A SER 243.A N ASN 247.A O no hydrogen 3.079 N/A SER 243.A OG GLU 225.A OE2 no hydrogen 2.386 N/A ASP 244.A N SER 227.A O no hydrogen 3.095 N/A ASN 245.A ND2 PHE 223.A O no hydrogen 2.968 N/A GLY 246.A N SER 243.A O no hydrogen 3.253 N/A ASN 247.A N ASN 245.A OD1 no hydrogen 3.115 N/A ILE 248.A N GLU 262.A O no hydrogen 2.948 N/A CYS 249.A N THR 241.A O no hydrogen 2.931 N/A CYS 249.A SG THR 261.A OG1 no hydrogen 3.334 N/A LEU 250.A N PHE 260.A O no hydrogen 2.832 N/A TRP 251.A N PHE 239.A O no hydrogen 2.874 N/A TRP 251.A NE1 THR 241.A OG1 no hydrogen 2.876 N/A LEU 253.A N PHE 237.A O no hydrogen 3.176 N/A ALA 254.A N SER 252.A OG no hydrogen 3.216 N/A LYS 255.A N SER 252.A O no hydrogen 3.120 N/A LYS 256.A NZ THR 204.A O no hydrogen 2.354 N/A LYS 257.A NZ ASP 209.A OD1 no hydrogen 2.790 N/A LYS 257.A NZ ASP 209.A OD2 no hydrogen 3.249 N/A PHE 260.A N LEU 250.A O no hydrogen 3.027 N/A GLU 262.A N ILE 248.A O no hydrogen 2.989 N/A ALA 265.A N GLY 246.A O no hydrogen 2.766 N/A HIS 266.A ND1 SER 294.A OG no hydrogen 2.930 N/A HIS 266.A NE2 SER 290.A OG no hydrogen 2.853 N/A GLY 267.A N ILE 264.A O no hydrogen 2.877 N/A LEU 269.A N GLN 272.A O no hydrogen 2.926 N/A PHE 274.A N GLY 267.A O no hydrogen 3.076 N/A ILE 276.A N SER 243.A O no hydrogen 3.070 N/A THR 277.A N GLY 291.A O no hydrogen 2.898 N/A THR 277.A OG1 GLY 291.A O no hydrogen 3.222 N/A THR 277.A OG1 VAL 322.A O no hydrogen 2.785 N/A SER 278.A N GLY 291.A O no hydrogen 2.962 N/A SER 278.A OG THR 277.A O no hydrogen 3.261 N/A TYR 280.A N ILE 289.A O no hydrogen 2.897 N/A ALA 281.A N SER 232.A OG no hydrogen 2.800 N/A TYR 284.A N VAL 234.A O no hydrogen 2.652 N/A TYR 284.A OH ASP 236.A OD1 no hydrogen 3.105 N/A SER 285.A N ILE 282.A O no hydrogen 3.256 N/A SER 285.A OG ILE 282.A O no hydrogen 2.872 N/A ASN 286.A N ARG 5.A O no hydrogen 3.139 N/A ASN 286.A ND2 ILE 302.A O no hydrogen 3.689 N/A VAL 287.A N SER 285.A OG no hydrogen 3.190 N/A PHE 288.A N TRP 300.A O no hydrogen 2.958 N/A ILE 289.A N TYR 280.A O no hydrogen 2.897 N/A SER 290.A N LYS 298.A O no hydrogen 2.869 N/A SER 290.A OG HIS 266.A NE2 no hydrogen 2.853 N/A GLY 291.A N SER 278.A O no hydrogen 2.892 N/A SER 292.A OG TRP 275.A O no hydrogen 2.331 N/A SER 294.A OG HIS 266.A ND1 no hydrogen 2.930 N/A SER 296.A OG GLU 314.A OE2 no hydrogen 2.949 N/A LEU 297.A N LEU 315.A O no hydrogen 2.896 N/A LYS 298.A N SER 290.A O no hydrogen 2.937 N/A LYS 298.A NZ ALA 265.A O no hydrogen 2.733 N/A VAL 299.A N GLY 313.A O no hydrogen 2.889 N/A TRP 300.A N PHE 288.A O no hydrogen 2.878 N/A TRP 300.A NE1 SER 290.A OG no hydrogen 3.029 N/A LYS 301.A N GLU 310.A O no hydrogen 2.682 N/A LYS 301.A NZ ASP 9.A OD1 no hydrogen 3.146 N/A LYS 301.A NZ ASP 9.A OD2 no hydrogen 2.794 N/A ILE 302.A N ASN 286.A O no hydrogen 2.437 N/A SER 303.A N SER 308.A O no hydrogen 2.762 N/A SER 303.A OG SER 308.A O no hydrogen 3.186 N/A LEU 306.A N SER 303.A O no hydrogen 3.029 N/A SER 308.A OG ARG 307.A O no hydrogen 2.642 N/A GLU 310.A N LYS 301.A O no hydrogen 2.703 N/A LEU 312.A N VAL 299.A O no hydrogen 2.723 N/A GLY 313.A N VAL 299.A O no hydrogen 2.981 N/A LEU 315.A N LEU 297.A O no hydrogen 2.894 N/A GLY 317.A N GLN 18.A OE1 no hydrogen 2.838 N/A LYS 319.A NZ SER 316.A O no hydrogen 3.114 N/A VAL 321.A N ALA 339.A O no hydrogen 3.060 N/A VAL 322.A N SER 292.A O no hydrogen 2.993 N/A THR 323.A N SER 337.A O no hydrogen 2.859 N/A THR 323.A OG1 LEU 28.A O no hydrogen 3.083 N/A THR 323.A OG1 SER 337.A O no hydrogen 3.126 N/A THR 323.A OG1 SER 337.A OG no hydrogen 2.609 N/A GLN 326.A N LEU 335.A O no hydrogen 2.869 N/A GLN 326.A NE2 ILE 325.A O no hydrogen 2.867 N/A VAL 328.A N ARG 333.A O no hydrogen 2.921 N/A GLU 329.A N GLN 35.A OE1 no hydrogen 2.982 N/A SER 330.A N LYS 331.A O no hydrogen 2.995 N/A LYS 331.A NZ ASP 364.A OD1 no hydrogen 3.179 N/A PHE 332.A N ILE 363.A O no hydrogen 2.976 N/A ARG 333.A N VAL 328.A O no hydrogen 2.840 N/A ARG 333.A NE SER 360.A OG no hydrogen 2.918 N/A ARG 333.A NH1 ILE 54.A O no hydrogen 2.893 N/A ARG 333.A NH1 LYS 59.A O no hydrogen 3.565 N/A ARG 333.A NH2 LYS 59.A O no hydrogen 2.946 N/A ARG 333.A NH2 SER 360.A OG no hydrogen 3.344 N/A ILE 334.A N ALA 361.A O no hydrogen 2.841 N/A LEU 335.A N GLN 326.A O no hydrogen 2.880 N/A ALA 336.A N TYR 359.A O no hydrogen 2.920 N/A SER 337.A N LYS 324.A O no hydrogen 2.930 N/A SER 337.A OG THR 323.A OG1 no hydrogen 2.609 N/A SER 337.A OG LYS 324.A O no hydrogen 3.500 N/A ILE 338.A N GLY 357.A O no hydrogen 2.878 N/A ALA 339.A N VAL 321.A O no hydrogen 2.998 N/A LYS 340.A N ASN 27.A OD1 no hydrogen 3.251 N/A ARG 343.A NH2 LEU 86.A O no hydrogen 3.537 N/A LEU 344.A N HIS 342.A ND1 no hydrogen 3.344 N/A GLY 345.A N HIS 342.A O no hydrogen 3.243 N/A ASN 350.A ND2 ASN 350.A O no hydrogen 3.313 N/A ARG 355.A NE LYS 319.A O no hydrogen 2.791 N/A ARG 355.A NH2 GLY 317.A O no hydrogen 2.514 N/A ARG 355.A NH2 LYS 319.A O no hydrogen 3.228 N/A GLY 357.A N ILE 338.A O no hydrogen 2.949 N/A ILE 358.A N THR 21.A O no hydrogen 2.907 N/A TYR 359.A N ALA 336.A O no hydrogen 2.909 N/A TYR 359.A OH GLN 18.A OE1 no hydrogen 2.785 N/A SER 360.A N SER 19.A O no hydrogen 2.899 N/A ALA 361.A N ILE 334.A O no hydrogen 2.913 N/A VAL 362.A N LYS 17.A O no hydrogen 2.874 N/A ILE 363.A N PHE 332.A O no hydrogen 2.829 N/A