Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4j5x_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLN 1.A N ASN 226.A OD1 no hydrogen 3.378 N/A THR 4.A N GLN 7.A OE1 no hydrogen 3.413 N/A GLU 6.A N GLU 6.A OE1 no hydrogen 3.060 N/A GLN 7.A N THR 4.A OG1 no hydrogen 2.700 N/A ARG 8.A N THR 4.A O no hydrogen 2.928 N/A MET 9.A N GLU 5.A O no hydrogen 2.821 N/A MET 10.A N GLN 7.A O no hydrogen 3.151 N/A ILE 11.A N GLN 7.A O no hydrogen 3.238 N/A ARG 12.A N ARG 8.A O no hydrogen 3.214 N/A LEU 14.A N MET 10.A O no hydrogen 3.232 N/A LEU 14.A N ILE 11.A O no hydrogen 2.937 N/A MET 15.A N ILE 11.A O no hydrogen 2.751 N/A ASP 16.A N ARG 12.A O no hydrogen 3.009 N/A ALA 17.A N GLU 13.A O no hydrogen 3.241 N/A GLN 18.A N LEU 14.A O no hydrogen 2.659 N/A GLN 18.A NE2 GLN 190.A OE1 no hydrogen 2.802 N/A MET 19.A N MET 15.A O no hydrogen 3.262 N/A LYS 20.A N ASP 16.A O no hydrogen 2.945 N/A LYS 20.A NZ ASP 16.A OD1 no hydrogen 2.684 N/A THR 21.A N GLN 18.A O no hydrogen 2.861 N/A THR 21.A OG1 ALA 17.A O no hydrogen 2.408 N/A THR 25.A N ASP 23.A OD1 no hydrogen 3.457 N/A THR 25.A OG1 ASP 23.A OD1 no hydrogen 2.937 N/A THR 25.A OG1 ASP 23.A OD2 no hydrogen 3.121 N/A THR 25.A OG1 SER 27.A OG no hydrogen 2.546 N/A PHE 26.A N ASP 23.A O no hydrogen 3.117 N/A SER 27.A N ASP 23.A OD2 no hydrogen 2.967 N/A SER 27.A OG ASP 23.A OD2 no hydrogen 3.513 N/A SER 27.A OG THR 25.A OG1 no hydrogen 2.546 N/A PHE 29.A N PHE 26.A O no hydrogen 3.071 N/A ARG 33.A N ASP 91.A OD2 no hydrogen 3.120 N/A ALA 43.A N ARG 39.A O no hydrogen 3.413 N/A LYS 44.A N GLU 40.A O no hydrogen 2.970 N/A LYS 44.A NZ ASP 262.A OD2 no hydrogen 2.948 N/A TRP 45.A N GLU 41.A O no hydrogen 3.503 N/A SER 46.A N ALA 42.A O no hydrogen 2.873 N/A SER 46.A OG ALA 42.A O no hydrogen 2.430 N/A GLN 47.A N ALA 43.A O no hydrogen 3.260 N/A GLN 47.A N LYS 44.A O no hydrogen 2.924 N/A VAL 48.A N LYS 44.A O no hydrogen 2.879 N/A ARG 49.A N TRP 45.A O no hydrogen 2.943 N/A LYS 50.A NZ GLN 47.A OE1 no hydrogen 3.294 N/A ASP 51.A N GLN 47.A O no hydrogen 3.119 N/A LEU 52.A N VAL 48.A O no hydrogen 3.388 N/A CYS 53.A N ARG 49.A O no hydrogen 2.913 N/A CYS 53.A SG LYS 50.A O no hydrogen 3.445 N/A SER 54.A OG ASP 51.A O no hydrogen 3.266 N/A SER 54.A OG GLU 167.A OE1 no hydrogen 2.522 N/A LEU 55.A N LEU 52.A O no hydrogen 3.058 N/A LYS 56.A NZ PRO 74.A O no hydrogen 3.361 N/A SER 58.A N CYS 153.A O no hydrogen 2.993 N/A LEU 59.A N TYR 71.A O no hydrogen 2.889 N/A LEU 61.A N TRP 69.A O no hydrogen 2.907 N/A ARG 62.A N ARG 149.A O no hydrogen 2.859 N/A GLY 63.A N SER 67.A O no hydrogen 2.920 N/A GLY 66.A N GLY 63.A O no hydrogen 3.132 N/A SER 67.A N ASP 65.A OD1 no hydrogen 2.547 N/A SER 67.A OG ASP 65.A OD1 no hydrogen 2.450 N/A SER 67.A OG ASP 65.A OD2 no hydrogen 3.280 N/A TRP 69.A N LEU 61.A O no hydrogen 2.623 N/A SER 77.A OG ASP 76.A O no hydrogen 2.782 N/A SER 84.A N GLU 81.A O no hydrogen 2.509 N/A SER 84.A OG GLU 81.A O no hydrogen 2.294 N/A LEU 86.A N PHE 83.A O no hydrogen 3.236 N/A HIS 88.A ND1 ARG 33.A O no hydrogen 3.044 N/A HIS 88.A NE2 TYR 152.A OH no hydrogen 2.653 N/A MET 89.A N LEU 85.A O no hydrogen 2.947 N/A ALA 90.A N LEU 86.A O no hydrogen 2.780 N/A ASP 91.A N PRO 87.A O no hydrogen 3.108 N/A MET 92.A N HIS 88.A O no hydrogen 2.995 N/A SER 93.A N MET 89.A O no hydrogen 2.909 N/A SER 93.A OG ALA 90.A O no hydrogen 2.204 N/A THR 94.A N ALA 90.A O no hydrogen 3.252 N/A THR 94.A OG1 ALA 90.A O no hydrogen 3.012 N/A TYR 95.A N ASP 91.A O no hydrogen 3.323 N/A MET 96.A N MET 92.A O no hydrogen 2.906 N/A PHE 97.A N SER 93.A O no hydrogen 2.651 N/A LYS 98.A N THR 94.A O no hydrogen 3.352 N/A GLY 99.A N TYR 95.A O no hydrogen 3.336 N/A ILE 100.A N PHE 97.A O no hydrogen 2.663 N/A ILE 101.A N PHE 97.A O no hydrogen 2.709 N/A SER 102.A OG LYS 98.A O no hydrogen 2.732 N/A ALA 104.A N ILE 100.A O no hydrogen 3.046 N/A VAL 106.A N SER 102.A O no hydrogen 3.243 N/A ILE 107.A N ALA 104.A O no hydrogen 2.762 N/A SER 108.A N GLU 13.A OE2 no hydrogen 2.906 N/A SER 108.A OG GLU 13.A OE1 no hydrogen 2.856 N/A SER 108.A OG GLU 13.A OE2 no hydrogen 3.157 N/A ARG 111.A N ILE 107.A O no hydrogen 2.800 N/A ASP 112.A N SER 108.A O no hydrogen 3.069 N/A LEU 113.A N TYR 109.A O no hydrogen 3.206 N/A ASP 117.A N PRO 114.A O no hydrogen 2.924 N/A GLN 118.A N PRO 114.A O no hydrogen 3.010 N/A ILE 119.A N ILE 115.A O no hydrogen 2.797 N/A SER 120.A N GLU 116.A O no hydrogen 3.081 N/A SER 120.A OG GLU 116.A O no hydrogen 3.225 N/A SER 120.A OG PRO 200.A O no hydrogen 3.536 N/A LEU 121.A N ASP 117.A O no hydrogen 2.802 N/A LEU 122.A N GLN 118.A O no hydrogen 3.016 N/A LYS 123.A N ILE 119.A O no hydrogen 3.194 N/A LYS 123.A NZ GLU 273.A O no hydrogen 2.833 N/A LYS 123.A NZ LEU 274.A O no hydrogen 3.254 N/A ALA 125.A N LEU 122.A O no hydrogen 2.932 N/A ALA 126.A N LEU 122.A O no hydrogen 2.563 N/A LEU 129.A N ALA 125.A O no hydrogen 2.670 N/A LEU 129.A N ALA 126.A O no hydrogen 3.287 N/A CYS 130.A N ALA 126.A O no hydrogen 3.293 N/A CYS 130.A SG ALA 126.A O no hydrogen 3.302 N/A GLN 131.A N PHE 127.A O no hydrogen 3.425 N/A ARG 133.A N LEU 129.A O no hydrogen 2.870 N/A ARG 133.A NE GLN 18.A OE1 no hydrogen 3.247 N/A ARG 133.A NH1 GLY 99.A O no hydrogen 2.771 N/A ARG 133.A NH2 GLN 18.A OE1 no hydrogen 3.219 N/A ARG 133.A NH2 THR 21.A OG1 no hydrogen 3.184 N/A ARG 133.A NH2 GLY 99.A O no hydrogen 3.339 N/A PHE 134.A N CYS 130.A O no hydrogen 2.686 N/A ASN 135.A N GLN 131.A O no hydrogen 2.907 N/A ASN 135.A ND2 HIS 173.A ND1 no hydrogen 3.212 N/A ASN 135.A ND2 HIS 173.A O no hydrogen 3.055 N/A THR 136.A N ARG 133.A O no hydrogen 2.959 N/A THR 136.A OG1 ARG 133.A O no hydrogen 2.413 N/A VAL 137.A N PHE 134.A O no hydrogen 3.216 N/A PHE 138.A N ASN 135.A O no hydrogen 3.391 N/A ASN 139.A N THR 144.A O no hydrogen 2.952 N/A ASN 139.A ND2 GLU 146.A OE2 no hydrogen 3.064 N/A GLU 141.A N ASN 139.A OD1 no hydrogen 2.973 N/A THR 142.A N ASN 139.A OD1 no hydrogen 3.323 N/A GLY 143.A N ASN 139.A O no hydrogen 2.542 N/A TRP 145.A N TYR 152.A O no hydrogen 3.144 N/A GLU 146.A N VAL 137.A O no hydrogen 2.815 N/A CYS 147.A N TRP 145.A O no hydrogen 2.731 N/A CYS 147.A SG TRP 145.A O no hydrogen 3.230 N/A SER 151.A N GLN 60.A O no hydrogen 2.637 N/A TYR 152.A OH HIS 88.A NE2 no hydrogen 2.653 N/A CYS 153.A N SER 58.A O no hydrogen 3.155 N/A CYS 153.A SG THR 142.A O no hydrogen 3.855 N/A CYS 153.A SG LEU 154.A O no hydrogen 3.781 N/A LEU 154.A N GLY 143.A O no hydrogen 2.901 N/A GLU 155.A N LYS 56.A O no hydrogen 3.406 N/A GLN 163.A N GLN 162.A OE1 no hydrogen 2.391 N/A LEU 166.A N GLN 163.A O no hydrogen 3.283 N/A GLU 167.A N LEU 164.A O no hydrogen 2.761 N/A LYS 171.A N GLU 167.A O no hydrogen 3.053 N/A PHE 172.A N PRO 168.A O no hydrogen 2.955 N/A HIS 173.A NE2 GLN 131.A OE1 no hydrogen 2.780 N/A TYR 174.A N LEU 170.A O no hydrogen 3.202 N/A MET 175.A N LYS 171.A O no hydrogen 2.650 N/A LEU 176.A N PHE 172.A O no hydrogen 2.648 N/A LYS 177.A N HIS 173.A O no hydrogen 2.826 N/A LYS 177.A NZ ASN 135.A O no hydrogen 2.624 N/A LYS 178.A N TYR 174.A O no hydrogen 3.175 N/A LEU 179.A N LEU 176.A O no hydrogen 3.130 N/A GLN 180.A N LYS 177.A O no hydrogen 3.363 N/A HIS 182.A N GLU 185.A OE1 no hydrogen 3.047 N/A HIS 182.A ND1 TYR 222.A OH no hydrogen 3.121 N/A GLU 184.A N GLU 184.A OE1 no hydrogen 2.603 N/A TYR 186.A N HIS 182.A O no hydrogen 2.978 N/A TYR 186.A OH ASN 135.A OD1 no hydrogen 2.457 N/A VAL 187.A N GLU 183.A O no hydrogen 2.965 N/A LEU 188.A N GLU 184.A O no hydrogen 2.895 N/A MET 189.A N GLU 185.A O no hydrogen 3.102 N/A GLN 190.A N TYR 186.A O no hydrogen 3.181 N/A GLN 190.A NE2 GLN 18.A OE1 no hydrogen 3.423 N/A ALA 191.A N VAL 187.A O no hydrogen 3.236 N/A ILE 192.A N LEU 188.A O no hydrogen 3.023 N/A SER 193.A N MET 189.A O no hydrogen 2.906 N/A LEU 194.A N GLN 190.A O no hydrogen 2.667 N/A PHE 195.A N ALA 191.A O no hydrogen 2.651 N/A SER 196.A OG ILE 192.A O no hydrogen 3.100 N/A SER 196.A OG SER 193.A O no hydrogen 3.033 N/A ASP 198.A N ASP 198.A OD1 no hydrogen 2.412 N/A ARG 199.A NH2 GLU 128.A OE2 no hydrogen 2.667 N/A ARG 199.A NH2 SER 193.A O no hydrogen 3.012 N/A LEU 203.A N ASP 117.A OD1 no hydrogen 2.584 N/A GLN 204.A N ASP 117.A OD2 no hydrogen 3.362 N/A HIS 205.A N LEU 203.A O no hydrogen 2.905 N/A ASP 209.A N HIS 205.A O no hydrogen 3.011 N/A GLN 210.A N ARG 206.A O no hydrogen 2.999 N/A LEU 211.A N VAL 207.A O no hydrogen 2.900 N/A GLN 212.A N VAL 208.A O no hydrogen 2.985 N/A GLN 212.A NE2 ILE 192.A O no hydrogen 2.571 N/A GLU 213.A N ASP 209.A O no hydrogen 3.151 N/A GLN 214.A N GLN 210.A O no hydrogen 3.010 N/A GLN 214.A NE2 GLN 210.A O no hydrogen 3.626 N/A PHE 215.A N LEU 211.A O no hydrogen 3.017 N/A ALA 216.A N GLN 212.A O no hydrogen 3.021 N/A ILE 217.A N GLU 213.A O no hydrogen 3.127 N/A THR 218.A N GLN 214.A O no hydrogen 3.185 N/A THR 218.A OG1 GLN 214.A O no hydrogen 2.486 N/A LEU 219.A N PHE 215.A O no hydrogen 3.076 N/A LYS 220.A N ALA 216.A O no hydrogen 2.782 N/A SER 221.A N ILE 217.A O no hydrogen 2.858 N/A SER 221.A OG ILE 217.A O no hydrogen 2.677 N/A SER 221.A OG THR 218.A O no hydrogen 3.323 N/A TYR 222.A N THR 218.A O no hydrogen 3.077 N/A TYR 222.A OH HIS 182.A ND1 no hydrogen 3.121 N/A GLU 224.A N LYS 220.A O no hydrogen 3.398 N/A CYS 225.A N SER 221.A O no hydrogen 2.938 N/A CYS 225.A SG GLN 1.A O no hydrogen 3.333 N/A CYS 225.A SG GLY 2.A O no hydrogen 3.524 N/A CYS 225.A SG SER 221.A O no hydrogen 3.170 N/A ASN 226.A N TYR 222.A O no hydrogen 2.932 N/A ARG 227.A NE GLU 185.A OE1 no hydrogen 3.369 N/A ARG 227.A NE GLU 185.A OE2 no hydrogen 2.752 N/A ARG 227.A NH2 GLN 180.A O no hydrogen 2.554 N/A ARG 227.A NH2 GLU 185.A OE1 no hydrogen 3.183 N/A HIS 232.A N PRO 228.A O no hydrogen 3.406 N/A MET 240.A N PHE 236.A O no hydrogen 2.378 N/A ALA 241.A N LEU 237.A O no hydrogen 2.855 N/A MET 242.A N LYS 238.A O no hydrogen 3.256 N/A LEU 243.A N ILE 239.A O no hydrogen 2.987 N/A THR 244.A N MET 240.A O no hydrogen 2.947 N/A THR 244.A OG1 MET 240.A O no hydrogen 3.330 N/A THR 244.A OG1 ALA 241.A O no hydrogen 2.298 N/A GLU 245.A N ALA 241.A O no hydrogen 2.886 N/A LEU 246.A N MET 242.A O no hydrogen 2.805 N/A ARG 247.A N THR 244.A O no hydrogen 2.888 N/A ARG 247.A NH1 ASP 198.A OD1 no hydrogen 3.535 N/A ARG 247.A NH1 ASP 198.A OD2 no hydrogen 2.737 N/A SER 248.A N GLU 245.A O no hydrogen 3.234 N/A ILE 249.A N GLU 245.A O no hydrogen 2.982 N/A ASN 250.A N LEU 246.A O no hydrogen 2.827 N/A ALA 251.A N ARG 247.A O no hydrogen 3.012 N/A GLN 252.A N SER 248.A O no hydrogen 2.659 N/A HIS 253.A N ILE 249.A O no hydrogen 2.988 N/A THR 254.A N ASN 250.A O no hydrogen 3.165 N/A THR 254.A OG1 ASN 250.A O no hydrogen 2.381 N/A GLN 255.A N ALA 251.A O no hydrogen 3.376 N/A ARG 256.A N GLN 252.A O no hydrogen 2.986 N/A ARG 256.A NH1 GLU 167.A OE2 no hydrogen 2.941 N/A ARG 256.A NH2 GLU 167.A OE2 no hydrogen 2.930 N/A LEU 257.A N HIS 253.A O no hydrogen 2.760 N/A LEU 258.A N THR 254.A O no hydrogen 2.914 N/A ARG 259.A N GLN 255.A O no hydrogen 3.067 N/A ARG 259.A NH2 ASP 51.A OD2 no hydrogen 2.541 N/A ILE 260.A N ARG 256.A O no hydrogen 3.138 N/A GLN 261.A N LEU 257.A O no hydrogen 2.928 N/A ASP 262.A N LEU 258.A O no hydrogen 3.111 N/A ASP 262.A N ARG 259.A O no hydrogen 3.187 N/A ILE 263.A N ARG 259.A O no hydrogen 3.302 N/A HIS 264.A N GLN 261.A O no hydrogen 3.411 N/A PHE 266.A N GLN 261.A OE1 no hydrogen 2.831 N/A MET 271.A N THR 268.A OG1 no hydrogen 2.986 N/A GLN 272.A N THR 268.A O no hydrogen 2.902 N/A GLU 273.A N PRO 269.A O no hydrogen 3.106 N/A LEU 274.A N LEU 270.A O no hydrogen 2.952 N/A PHE 275.A N MET 271.A O no hydrogen 2.779 N/A PHE 275.A N GLN 272.A O no hydrogen 3.231 N/A GLY 276.A N GLU 273.A O no hydrogen 3.428 N/A ILE 277.A N GLN 272.A O no hydrogen 2.854 N/A ARG 283.A N SER 279.A O no hydrogen 2.539 N/A ARG 283.A NE SER 279.A OG no hydrogen 3.362 N/A HIS 284.A N LEU 280.A O no hydrogen 3.340 N/A ILE 286.A N GLU 273.A OE1 no hydrogen 2.735 N/A LEU 287.A N GLU 273.A OE1 no hydrogen 2.856 N/A HIS 288.A N HIS 284.A O no hydrogen 3.004 N/A ARG 289.A N LYS 285.A O no hydrogen 3.430 N/A LEU 290.A N ILE 286.A O no hydrogen 3.352 N/A LEU 291.A N HIS 288.A O no hydrogen 3.300 N/A