Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4je0_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 3.A N TYR 48.A O no hydrogen 2.855 N/A ASN 4.A N ASN 2.A OD1 no hydrogen 3.013 N/A ASN 4.A ND2 THR 50.A OG1 no hydrogen 3.131 N/A LEU 6.A N VAL 3.A O no hydrogen 2.724 N/A ILE 7.A N ASN 4.A O no hydrogen 3.359 N/A THR 8.A N LYS 38.A O no hydrogen 3.061 N/A ASN 10.A N GLN 36.A O no hydrogen 2.992 N/A THR 11.A OG1 SER 35.A OG no hydrogen 2.761 N/A THR 12.A N LYS 34.A O no hydrogen 2.833 N/A THR 14.A N ALA 32.A O no hydrogen 3.042 N/A VAL 16.A N TYR 30.A O no hydrogen 3.007 N/A ALA 18.A N ASP 29.A OD1 no hydrogen 2.884 N/A LYS 23.A N ASN 21.A OD1 no hydrogen 3.156 N/A LYS 23.A NZ GLN 146.A OE1 no hydrogen 3.092 N/A VAL 25.A N ASP 29.A OD2 no hydrogen 2.696 N/A GLN 28.A N VAL 25.A O no hydrogen 3.095 N/A ASP 29.A N VAL 25.A O no hydrogen 2.922 N/A TYR 30.A N VAL 16.A O no hydrogen 3.424 N/A LEU 31.A N ILE 115.A O no hydrogen 2.719 N/A ALA 32.A N THR 14.A O no hydrogen 2.857 N/A LEU 33.A N TYR 113.A O no hydrogen 2.764 N/A LYS 34.A N THR 12.A O no hydrogen 3.025 N/A SER 35.A N ILE 111.A O no hydrogen 3.012 N/A SER 35.A OG ASN 10.A O no hydrogen 3.487 N/A SER 35.A OG THR 11.A OG1 no hydrogen 2.761 N/A GLN 36.A N ASN 10.A O no hydrogen 3.058 N/A LYS 38.A N THR 8.A O no hydrogen 2.750 N/A VAL 39.A N VAL 108.A O no hydrogen 2.996 N/A ASP 40.A N LEU 6.A O no hydrogen 3.066 N/A LYS 42.A N ASP 40.A OD1 no hydrogen 3.046 N/A VAL 43.A N ASP 40.A O no hydrogen 3.028 N/A LYS 44.A N ASP 47.A OD2 no hydrogen 2.850 N/A LYS 44.A NZ ASP 47.A OD1 no hydrogen 3.046 N/A SER 45.A N ASP 103.A OD1 no hydrogen 3.427 N/A GLY 46.A N PHE 98.A O no hydrogen 2.921 N/A ASP 47.A N LYS 44.A O no hydrogen 3.052 N/A TYR 48.A N LYS 1.A O no hydrogen 2.813 N/A PHE 49.A N TYR 96.A O no hydrogen 2.943 N/A THR 50.A N ASN 4.A OD1 no hydrogen 2.902 N/A ILE 51.A N ILE 94.A O no hydrogen 2.863 N/A LYS 52.A N THR 133.A O no hydrogen 2.921 N/A LYS 52.A NZ ASN 92.A O no hydrogen 3.142 N/A TYR 53.A N ASN 92.A O no hydrogen 3.327 N/A SER 54.A N ASN 131.A O no hydrogen 2.907 N/A SER 54.A OG THR 56.A OG1 no hydrogen 2.803 N/A SER 54.A OG ASN 131.A O no hydrogen 3.528 N/A THR 56.A OG1 SER 54.A OG no hydrogen 2.803 N/A THR 56.A OG1 GLU 129.A O no hydrogen 2.693 N/A VAL 57.A N SER 54.A O no hydrogen 2.917 N/A GLN 58.A N TYR 116.A O no hydrogen 2.849 N/A GLN 58.A NE2 TYR 60.A O no hydrogen 2.758 N/A GLU 65.A N ASN 63.A OD1 no hydrogen 2.941 N/A ASP 66.A N ASN 63.A O no hydrogen 2.885 N/A LYS 68.A N GLU 65.A O no hydrogen 3.079 N/A ASN 69.A N ASP 66.A O no hydrogen 2.970 N/A ILE 70.A N ILE 67.A O no hydrogen 3.209 N/A ILE 73.A N ALA 83.A O no hydrogen 2.869 N/A ASP 75.A N GLU 80.A O no hydrogen 2.815 N/A ASN 77.A N ASP 75.A OD1 no hydrogen 2.876 N/A GLY 79.A N ASP 75.A O no hydrogen 2.704 N/A GLU 80.A N ASN 78.A OD1 no hydrogen 2.889 N/A ILE 82.A N ILE 73.A O no hydrogen 2.792 N/A ALA 83.A N ILE 73.A O no hydrogen 3.347 N/A THR 84.A N THR 97.A O no hydrogen 2.843 N/A THR 84.A OG1 THR 97.A O no hydrogen 3.517 N/A ALA 85.A N ASP 72.A OD1 no hydrogen 3.028 N/A LYS 86.A N THR 95.A O no hydrogen 2.886 N/A HIS 87.A NE2 ILE 70.A O no hydrogen 2.906 N/A ASP 88.A N LEU 93.A O no hydrogen 2.877 N/A ASN 91.A N ASP 88.A O no hydrogen 2.936 N/A ASN 91.A ND2 ASP 88.A OD2 no hydrogen 2.700 N/A ASN 92.A N THR 89.A O no hydrogen 3.139 N/A ASN 92.A ND2 TYR 53.A O no hydrogen 3.335 N/A ASN 92.A ND2 SER 54.A O no hydrogen 2.975 N/A LEU 93.A N ASP 88.A O no hydrogen 3.231 N/A ILE 94.A N ILE 51.A O no hydrogen 2.792 N/A THR 95.A N LYS 86.A O no hydrogen 2.856 N/A TYR 96.A N PHE 49.A O no hydrogen 2.831 N/A TYR 96.A OH TYR 113.A OH no hydrogen 2.907 N/A THR 97.A N THR 84.A O no hydrogen 2.842 N/A PHE 98.A N ASP 47.A O no hydrogen 2.794 N/A THR 99.A N ILE 82.A O no hydrogen 2.917 N/A THR 99.A OG1 THR 81.A O no hydrogen 2.594 N/A THR 99.A OG1 ILE 82.A O no hydrogen 3.402 N/A TYR 101.A N THR 99.A OG1 no hydrogen 3.201 N/A TYR 101.A OH ASP 75.A OD2 no hydrogen 2.398 N/A VAL 102.A N THR 99.A O no hydrogen 3.429 N/A ASP 103.A N ASP 100.A O no hydrogen 2.846 N/A ARG 104.A N ASP 100.A O no hydrogen 3.117 N/A ARG 104.A N TYR 101.A O no hydrogen 3.243 N/A ARG 104.A NH1 ASP 100.A OD1 no hydrogen 2.379 N/A PHE 105.A N TYR 101.A O no hydrogen 2.882 N/A SER 107.A N ASP 41.A OD1 no hydrogen 2.870 N/A ILE 111.A N SER 35.A O no hydrogen 2.907 N/A TYR 113.A N LEU 33.A O no hydrogen 2.793 N/A TYR 113.A OH TYR 96.A OH no hydrogen 2.907 N/A ILE 115.A N LEU 31.A O no hydrogen 2.749 N/A TYR 116.A N GLN 58.A O no hydrogen 2.847 N/A ASP 119.A N ASP 117.A OD1 no hydrogen 3.034 N/A ILE 121.A N ALA 118.A O no hydrogen 2.893 N/A LYS 125.A N ILE 145.A O no hydrogen 3.145 N/A ASP 127.A N ASN 144.A OD1 no hydrogen 2.582 N/A VAL 128.A N ALA 143.A O no hydrogen 2.805 N/A PHE 130.A N THR 141.A O no hydrogen 2.745 N/A ASN 131.A N SER 54.A OG no hydrogen 3.074 N/A ASN 131.A ND2 GLU 129.A OE2 no hydrogen 2.938 N/A VAL 132.A N THR 139.A O no hydrogen 3.068 N/A THR 133.A N LYS 52.A O no hydrogen 2.760 N/A THR 133.A OG1 THR 138.A OG1 no hydrogen 2.824 N/A ILE 134.A N ASP 137.A O no hydrogen 2.764 N/A GLY 135.A N THR 50.A O no hydrogen 2.976 N/A ASP 137.A N ILE 134.A O no hydrogen 3.047 N/A THR 138.A OG1 THR 133.A OG1 no hydrogen 2.824 N/A THR 139.A N VAL 132.A O no hydrogen 2.802 N/A THR 141.A N PHE 130.A O no hydrogen 2.853 N/A THR 142.A OG1 VAL 128.A O no hydrogen 3.566 N/A ALA 143.A N VAL 128.A O no hydrogen 2.926 N/A ILE 145.A N LYS 125.A O no hydrogen 2.827 N/A GLN 146.A N ILE 24.A O no hydrogen 3.174 N/A TYR 147.A N SER 124.A OG no hydrogen 2.942 N/A TYR 147.A OH ILE 121.A O no hydrogen 2.686 N/A VAL 151.A N ILE 158.A O no hydrogen 2.922 N/A ARG 153.A N ASN 156.A O no hydrogen 3.008 N/A ARG 153.A NE SER 300.A O no hydrogen 2.714 N/A ARG 153.A NH2 SER 300.A O no hydrogen 2.933 N/A ARG 153.A NH2 SER 300.A OG no hydrogen 3.158 N/A ASN 155.A N ASN 298.A OD1 no hydrogen 2.929 N/A ASN 156.A N ARG 153.A O no hydrogen 2.993 N/A ASN 156.A ND2 ARG 299.A O no hydrogen 2.926 N/A SER 157.A OG SER 187.A OG no hydrogen 3.279 N/A ILE 158.A N VAL 151.A O no hydrogen 2.973 N/A GLY 159.A N TYR 183.A O no hydrogen 3.088 N/A SER 160.A OG ASN 305.A OD1 no hydrogen 2.870 N/A ALA 161.A N THR 181.A O no hydrogen 3.019 N/A THR 163.A N LYS 179.A O no hydrogen 2.945 N/A THR 165.A N LEU 62.A O no hydrogen 2.761 N/A VAL 166.A N TYR 177.A O no hydrogen 2.885 N/A HIS 168.A N PRO 175.A O no hydrogen 2.946 N/A HIS 168.A ND1 ASP 174.A O no hydrogen 2.821 N/A HIS 168.A NE2 GLU 65.A OE2 no hydrogen 2.738 N/A GLY 170.A N THR 281.A O no hydrogen 2.774 N/A ASN 171.A N HIS 168.A O no hydrogen 3.125 N/A GLU 173.A N ASN 171.A OD1 no hydrogen 3.182 N/A ASP 174.A N ASN 171.A OD1 no hydrogen 3.100 N/A TYR 177.A N VAL 166.A O no hydrogen 2.963 N/A TYR 177.A OH GLU 164.A OE1 no hydrogen 2.507 N/A TYR 178.A N THR 276.A O no hydrogen 2.930 N/A TYR 178.A OH GLN 290.A OE1 no hydrogen 2.545 N/A LYS 179.A N GLU 164.A O no hydrogen 2.817 N/A LYS 179.A NZ ASP 275.A OD2 no hydrogen 3.102 N/A GLN 180.A N VAL 274.A O no hydrogen 3.032 N/A GLN 180.A NE2 GLN 290.A O no hydrogen 3.218 N/A GLN 180.A NE2 ASN 305.A OD1 no hydrogen 2.942 N/A THR 181.A N ALA 161.A O no hydrogen 2.858 N/A VAL 182.A N VAL 273.A O no hydrogen 2.774 N/A TYR 183.A N GLY 159.A O no hydrogen 2.690 N/A TYR 183.A OH ASN 231.A O no hydrogen 2.712 N/A VAL 184.A N TYR 271.A O no hydrogen 2.738 N/A ASN 185.A N SER 157.A O no hydrogen 3.080 N/A ASN 185.A ND2 LYS 189.A O no hydrogen 3.010 N/A ASN 185.A ND2 ASN 269.A O no hydrogen 2.815 N/A SER 187.A N SER 157.A OG no hydrogen 3.107 N/A SER 187.A OG SER 157.A OG no hydrogen 3.279 N/A GLU 188.A N ASN 185.A O no hydrogen 2.964 N/A LYS 189.A N ASN 185.A OD1 no hydrogen 2.907 N/A LYS 189.A NZ ASN 155.A OD1 no hydrogen 2.975 N/A LEU 191.A N ILE 267.A O no hydrogen 2.796 N/A ASN 193.A ND2 ASP 296.A OD1 no hydrogen 2.895 N/A ALA 194.A N GLY 265.A O no hydrogen 2.885 N/A LYS 195.A N THR 294.A O no hydrogen 2.865 N/A LEU 196.A N VAL 262.A O no hydrogen 2.880 N/A LYS 197.A N THR 292.A O no hydrogen 2.815 N/A VAL 198.A N VAL 260.A O no hydrogen 2.902 N/A ALA 200.A N ASP 258.A O no hydrogen 3.009 N/A ASP 204.A N HIS 202.A ND1 no hydrogen 3.250 N/A TYR 205.A N HIS 202.A O no hydrogen 3.101 N/A ASN 208.A N TYR 205.A O no hydrogen 3.100 N/A ASN 208.A ND2 VAL 289.A O no hydrogen 2.828 N/A VAL 209.A N THR 287.A O no hydrogen 2.923 N/A GLY 210.A N ASN 208.A OD1 no hydrogen 2.875 N/A GLN 211.A N TYR 178.A OH no hydrogen 3.088 N/A GLN 211.A NE2 LYS 277.A O no hydrogen 3.328 N/A ILE 212.A N ASP 258.A OD1 no hydrogen 3.002 N/A ASN 213.A N THR 217.A OG1 no hydrogen 3.155 N/A ASN 213.A ND2 GLN 211.A OE1 no hydrogen 3.315 N/A ASP 215.A N ASN 213.A OD1 no hydrogen 2.823 N/A VAL 216.A N ASN 213.A OD1 no hydrogen 3.085 N/A THR 217.A N ASN 213.A O no hydrogen 2.917 N/A THR 217.A OG1 ASN 213.A O no hydrogen 3.328 N/A THR 217.A OG1 THR 276.A OG1 no hydrogen 2.810 N/A LYS 218.A N ASP 275.A O no hydrogen 2.726 N/A ILE 221.A N THR 245.A OG1 no hydrogen 2.925 N/A TYR 222.A N VAL 272.A O no hydrogen 2.862 N/A GLN 223.A N ILE 242.A O no hydrogen 2.820 N/A ALA 224.A N SER 270.A O no hydrogen 2.963 N/A ASP 227.A N GLU 188.A OE2 no hydrogen 2.819 N/A TYR 228.A N PRO 225.A O no hydrogen 3.188 N/A TYR 228.A OH GLN 240.A OE1 no hydrogen 2.532 N/A ASN 231.A ND2 ALA 118.A O no hydrogen 3.001 N/A LYS 232.A N PRO 122.A O no hydrogen 2.787 N/A LYS 232.A NZ PRO 148.A O no hydrogen 2.849 N/A GLY 233.A N ASN 231.A OD1 no hydrogen 2.759 N/A TYR 234.A N ASN 231.A O no hydrogen 2.992 N/A ASP 235.A N ASN 231.A OD1 no hydrogen 3.187 N/A ASN 239.A N ASN 237.A OD1 no hydrogen 3.267 N/A GLN 240.A N ASN 237.A O no hydrogen 2.976 N/A LEU 241.A N THR 238.A O no hydrogen 3.050 N/A ILE 242.A N GLN 223.A O no hydrogen 3.077 N/A VAL 244.A N ILE 221.A O no hydrogen 2.934 N/A THR 245.A N ASP 243.A OD1 no hydrogen 2.976 N/A THR 245.A OG1 ILE 221.A O no hydrogen 3.400 N/A THR 245.A OG1 ASP 243.A OD1 no hydrogen 2.560 N/A GLN 247.A N VAL 244.A O no hydrogen 2.837 N/A PHE 248.A N THR 245.A O no hydrogen 3.049 N/A LYS 249.A N GLU 246.A O no hydrogen 3.374 N/A LYS 251.A N PHE 248.A O no hydrogen 2.971 N/A LYS 251.A NZ ASP 250.A OD2 no hydrogen 3.520 N/A THR 253.A N ASN 261.A O no hydrogen 3.036 N/A GLY 255.A N SER 259.A O no hydrogen 2.996 N/A SER 259.A OG ALA 256.A O no hydrogen 2.684 N/A VAL 260.A N VAL 198.A O no hydrogen 2.859 N/A ASN 261.A N THR 253.A O no hydrogen 2.851 N/A ASN 261.A ND2 THR 253.A O no hydrogen 3.620 N/A VAL 262.A N LEU 196.A O no hydrogen 2.708 N/A ASP 263.A N LYS 251.A O no hydrogen 2.919 N/A PHE 264.A N ALA 194.A O no hydrogen 2.824 N/A GLY 265.A N ALA 194.A O no hydrogen 3.259 N/A GLY 265.A N ASP 263.A OD1 no hydrogen 3.181 N/A ILE 267.A N LEU 191.A O no hydrogen 3.073 N/A ASN 269.A ND2 ALA 224.A O no hydrogen 3.518 N/A TYR 271.A N VAL 184.A O no hydrogen 2.842 N/A VAL 272.A N TYR 222.A O no hydrogen 2.820 N/A VAL 273.A N VAL 182.A O no hydrogen 2.750 N/A ASP 275.A N LYS 218.A O no hydrogen 2.826 N/A THR 276.A N TYR 178.A O no hydrogen 3.140 N/A THR 276.A OG1 GLN 211.A O no hydrogen 2.624 N/A THR 276.A OG1 THR 217.A OG1 no hydrogen 2.810 N/A PHE 278.A N GLY 176.A O no hydrogen 3.031 N/A GLU 279.A N VAL 209.A O no hydrogen 2.766 N/A SER 283.A N THR 281.A OG1 no hydrogen 3.325 N/A SER 285.A N SER 283.A OG no hydrogen 2.841 N/A VAL 289.A N ASN 208.A OD1 no hydrogen 2.975 N/A GLN 290.A N ASN 305.A O no hydrogen 3.077 N/A GLN 290.A NE2 GLN 180.A OE1 no hydrogen 2.796 N/A ALA 291.A N THR 303.A O no hydrogen 2.930 N/A THR 292.A N LYS 197.A O no hydrogen 2.731 N/A THR 292.A OG1 SER 302.A OG no hydrogen 2.882 N/A LEU 293.A N VAL 301.A O no hydrogen 2.907 N/A THR 294.A N LYS 195.A O no hydrogen 2.908 N/A THR 294.A OG1 LYS 195.A O no hydrogen 3.540 N/A SER 295.A OG ASN 156.A OD1 no hydrogen 2.632 N/A ASP 296.A N THR 192.A O no hydrogen 2.877 N/A ASN 298.A N SER 295.A O no hydrogen 3.374 N/A ASN 298.A ND2 SER 295.A OG no hydrogen 2.859 N/A ARG 299.A N ASP 154.A OD2 no hydrogen 2.862 N/A ARG 299.A NE ASP 154.A OD1 no hydrogen 3.412 N/A ARG 299.A NE ASP 154.A OD2 no hydrogen 2.860 N/A ARG 299.A NH2 ASP 154.A OD1 no hydrogen 2.617 N/A VAL 301.A N LEU 293.A O no hydrogen 2.994 N/A SER 302.A OG THR 292.A OG1 no hydrogen 2.882 N/A THR 303.A N ALA 291.A O no hydrogen 2.837 N/A GLY 304.A N THR 303.A OG1 no hydrogen 2.736 N/A ASN 305.A N GLN 290.A O no hydrogen 2.995 N/A ASN 305.A ND2 SER 160.A O no hydrogen 3.333 N/A ALA 307.A N LEU 288.A O no hydrogen 2.763 N/A