Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4jpv_G.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TRP 2.A NE1 GLU 48.A OE2 no hydrogen 2.909 N/A LYS 3.A N GLN 340.A O no hydrogen 3.141 N/A LYS 3.A NZ GLU 342.A OE1 no hydrogen 2.894 N/A ALA 5.A N VAL 338.A O no hydrogen 3.358 N/A LEU 9.A N GLN 60.A OE1 no hydrogen 3.237 N/A PHE 10.A N CYS 102.A O no hydrogen 2.924 N/A CYS 11.A SG ALA 30.A O no hydrogen 3.357 N/A ALA 12.A N HIS 100.A O no hydrogen 2.853 N/A SER 13.A N VAL 32.A O no hydrogen 2.995 N/A ALA 15.A N SER 13.A OG no hydrogen 3.319 N/A LYS 16.A N ASN 24.A OD1 no hydrogen 3.190 N/A GLU 19.A N LYS 16.A O no hydrogen 3.207 N/A THR 20.A OG1 SER 93.A OG no hydrogen 3.386 N/A VAL 22.A N SER 93.A O no hydrogen 3.285 N/A HIS 23.A N GLU 21.A OE2 no hydrogen 3.355 N/A HIS 23.A ND1 GLU 21.A OE2 no hydrogen 2.354 N/A ASN 24.A N GLU 21.A OE1 no hydrogen 2.793 N/A ASN 24.A ND2 GLU 21.A OE1 no hydrogen 2.871 N/A VAL 25.A N GLU 21.A O no hydrogen 3.017 N/A TRP 26.A N VAL 22.A O no hydrogen 3.133 N/A ALA 27.A N HIS 23.A O no hydrogen 3.006 N/A THR 28.A N ASN 24.A O no hydrogen 3.120 N/A THR 28.A N VAL 25.A O no hydrogen 3.174 N/A THR 28.A OG1 ASN 24.A O no hydrogen 3.001 N/A HIS 29.A N TRP 26.A O no hydrogen 2.958 N/A HIS 29.A ND1 VAL 25.A O no hydrogen 3.168 N/A ALA 30.A N TRP 26.A O no hydrogen 2.966 N/A CYS 31.A N ALA 27.A O no hydrogen 3.047 N/A VAL 32.A N CYS 11.A O no hydrogen 2.859 N/A THR 34.A OG1 ASP 14.A OD1 no hydrogen 3.485 N/A THR 34.A OG1 ASP 14.A OD2 no hydrogen 3.177 N/A ILE 41.A N SER 128.A O no hydrogen 3.187 N/A LEU 43.A N VAL 126.A O no hydrogen 2.978 N/A GLU 48.A N CYS 123.A O no hydrogen 3.323 N/A PHE 50.A N GLY 121.A O no hydrogen 3.043 N/A MET 52.A N GLY 119.A O no hydrogen 2.991 N/A TRP 53.A N ASN 51.A OD1 no hydrogen 3.081 N/A LYS 54.A N ASN 51.A O no hydrogen 2.929 N/A MET 57.A N ASN 55.A OD1 no hydrogen 3.235 N/A VAL 58.A N ASN 55.A O no hydrogen 2.907 N/A GLN 60.A NE2 THR 7.A O no hydrogen 3.016 N/A GLN 60.A NE2 ASN 56.A OD1 no hydrogen 2.853 N/A MET 61.A N MET 57.A O no hydrogen 3.305 N/A GLN 62.A N VAL 58.A O no hydrogen 2.935 N/A GLU 63.A N GLU 59.A O no hydrogen 3.000 N/A ASP 64.A N GLN 60.A O no hydrogen 2.997 N/A VAL 65.A N MET 61.A O no hydrogen 3.034 N/A ILE 66.A N GLN 62.A O no hydrogen 3.180 N/A SER 67.A N GLU 63.A O no hydrogen 3.100 N/A LEU 68.A N ASP 64.A O no hydrogen 2.881 N/A TRP 69.A N VAL 65.A O no hydrogen 2.784 N/A ASP 70.A N ILE 66.A O no hydrogen 3.028 N/A GLN 71.A N SER 67.A O no hydrogen 3.362 N/A SER 72.A N LEU 68.A O no hydrogen 3.173 N/A SER 72.A OG LEU 68.A O no hydrogen 3.111 N/A LEU 73.A N TRP 69.A O no hydrogen 3.104 N/A GLN 74.A NE2 ALA 88.A O no hydrogen 3.637 N/A CYS 76.A N MET 285.A O no hydrogen 2.758 N/A CYS 76.A SG MET 285.A O no hydrogen 3.641 N/A LYS 78.A N ILE 85.A O no hydrogen 3.046 N/A THR 80.A N SER 83.A O no hydrogen 2.768 N/A THR 80.A OG1 SER 83.A O no hydrogen 3.064 N/A SER 83.A N THR 80.A O no hydrogen 3.041 N/A ILE 85.A N LYS 78.A O no hydrogen 2.757 N/A GLN 87.A N CYS 76.A O no hydrogen 3.007 N/A CYS 89.A SG GLN 87.A O no hydrogen 4.034 N/A LYS 91.A NZ ALA 287.A O no hydrogen 3.389 N/A LYS 91.A NZ PRO 288.A O no hydrogen 3.279 N/A SER 93.A OG THR 20.A OG1 no hydrogen 3.386 N/A ASP 95.A N GLU 21.A OE2 no hydrogen 2.641 N/A ILE 99.A N ILE 135.A O no hydrogen 2.834 N/A HIS 100.A N ALA 12.A O no hydrogen 2.922 N/A HIS 100.A ND1 ALA 12.A O no hydrogen 3.243 N/A TYR 101.A N THR 132.A OG1 no hydrogen 2.876 N/A TYR 101.A OH ASP 64.A OD2 no hydrogen 2.673 N/A CYS 102.A N PHE 10.A O no hydrogen 2.689 N/A CYS 102.A SG HIS 100.A O no hydrogen 4.037 N/A THR 103.A N GLN 130.A O no hydrogen 3.476 N/A THR 103.A OG1 TYR 107.A O no hydrogen 3.457 N/A TYR 107.A N PRO 104.A O no hydrogen 3.164 N/A TYR 107.A OH GLN 340.A OE1 no hydrogen 3.365 N/A VAL 108.A N VAL 339.A O no hydrogen 3.089 N/A ILE 109.A N VAL 129.A O no hydrogen 3.416 N/A LEU 110.A N LYS 337.A O no hydrogen 2.597 N/A LYS 111.A N SER 127.A O no hydrogen 3.157 N/A CYS 112.A N LYS 335.A O no hydrogen 3.162 N/A ASN 113.A N ASN 125.A O no hydrogen 2.893 N/A ASN 113.A ND2 ASN 125.A O no hydrogen 2.914 N/A ASN 113.A ND2 ASN 125.A OD1 no hydrogen 3.615 N/A ASN 113.A ND2 SER 127.A OG no hydrogen 3.289 N/A THR 120.A N ASN 118.A OD1 no hydrogen 2.954 N/A GLY 121.A N PHE 50.A O no hydrogen 3.216 N/A CYS 123.A N GLU 48.A O no hydrogen 3.008 N/A CYS 123.A SG ASP 114.A OD1 no hydrogen 3.213 N/A CYS 123.A SG ASN 125.A O no hydrogen 3.961 N/A LYS 124.A N ASP 114.A OD2 no hydrogen 3.161 N/A ASN 125.A N ASP 114.A OD1 no hydrogen 2.961 N/A SER 127.A N LYS 111.A O no hydrogen 3.097 N/A SER 127.A OG GLU 40.A OE2 no hydrogen 2.476 N/A SER 128.A N ILE 41.A O no hydrogen 2.932 N/A VAL 129.A N ILE 109.A O no hydrogen 3.212 N/A THR 132.A N TYR 101.A O no hydrogen 3.002 N/A THR 132.A OG1 HIS 133.A O no hydrogen 3.040 N/A HIS 133.A N TYR 336.A OH no hydrogen 3.191 N/A HIS 133.A ND1 TYR 336.A OH no hydrogen 2.573 N/A ILE 135.A N ILE 99.A O no hydrogen 3.190 N/A VAL 138.A N LYS 136.A O no hydrogen 2.792 N/A SER 140.A OG LEU 143.A O no hydrogen 2.746 N/A THR 141.A N HIS 237.A O no hydrogen 2.983 N/A THR 141.A OG1 GLU 232.A O no hydrogen 2.911 N/A THR 141.A OG1 MET 235.A O no hydrogen 3.360 N/A GLN 142.A N GLY 321.A O no hydrogen 2.833 N/A GLN 142.A NE2 ILE 233.A O no hydrogen 2.642 N/A LEU 143.A N THR 141.A O no hydrogen 2.514 N/A LEU 144.A N GLY 302.A O no hydrogen 2.803 N/A ASN 146.A N ASN 299.A O no hydrogen 3.042 N/A SER 148.A N GLU 332.A OE2 no hydrogen 2.948 N/A SER 148.A OG GLU 332.A OE1 no hydrogen 3.375 N/A SER 148.A OG GLU 332.A OE2 no hydrogen 3.001 N/A ALA 150.A N LEU 172.A O no hydrogen 2.831 N/A ILE 155.A N HIS 171.A O no hydrogen 3.255 N/A ARG 157.A N ILE 169.A O no hydrogen 2.862 N/A ARG 157.A NH1 HIS 171.A ND1 no hydrogen 2.969 N/A ARG 157.A NH2 PHE 117.A O no hydrogen 2.811 N/A THR 162.A OG1 ASN 160.A OD1 no hydrogen 2.809 N/A ASP 163.A N ASN 160.A O no hydrogen 3.002 N/A ALA 165.A N ASP 163.A OD1 no hydrogen 2.912 N/A LYS 166.A N ASP 163.A O no hydrogen 3.404 N/A LYS 166.A NZ GLU 159.A OE1 no hydrogen 3.282 N/A ILE 168.A N LEU 305.A O no hydrogen 3.025 N/A ILE 169.A N ARG 157.A O no hydrogen 2.709 N/A VAL 170.A N ILE 303.A O no hydrogen 2.819 N/A HIS 171.A N ILE 155.A O no hydrogen 2.889 N/A HIS 171.A NE2 SER 148.A O no hydrogen 2.534 N/A LEU 172.A N THR 301.A O no hydrogen 3.035 N/A VAL 176.A N ILE 300.A O no hydrogen 3.445 N/A ILE 178.A N SER 298.A O no hydrogen 2.683 N/A ASN 179.A N GLU 195.A O no hydrogen 3.019 N/A CYS 180.A N CYS 296.A O no hydrogen 2.997 N/A THR 181.A N TYR 193.A O no hydrogen 2.982 N/A ARG 182.A N ILE 294.A O no hydrogen 3.031 N/A ARG 182.A NE PRO 183.A O no hydrogen 2.988 N/A ARG 182.A NH1 ILE 189.A O no hydrogen 2.867 N/A ARG 182.A NH2 ILE 290.A O no hydrogen 3.224 N/A ARG 182.A NH2 GLY 292.A O no hydrogen 2.488 N/A ARG 190.A N ASP 188.A OD1 no hydrogen 3.196 N/A ARG 190.A NH1 GLN 273.A OE1 no hydrogen 2.286 N/A LYS 191.A N ASP 188.A O no hydrogen 3.268 N/A ALA 192.A N CYS 269.A O no hydrogen 2.968 N/A TYR 193.A N THR 181.A O no hydrogen 3.117 N/A CYS 194.A N LEU 267.A O no hydrogen 2.696 N/A GLU 195.A N ASN 179.A O no hydrogen 2.680 N/A ILE 196.A N ILE 265.A O no hydrogen 2.940 N/A THR 199.A OG1 ASN 262.A O no hydrogen 3.115 N/A LYS 200.A N ASN 197.A OD1 no hydrogen 3.267 N/A TRP 201.A N ASN 197.A O no hydrogen 3.008 N/A TRP 201.A NE1 LEU 252.A O no hydrogen 2.590 N/A ASN 202.A N GLY 198.A O no hydrogen 2.988 N/A VAL 204.A N LYS 200.A O no hydrogen 3.281 N/A LEU 205.A N TRP 201.A O no hydrogen 2.748 N/A LYS 206.A N ASN 202.A O no hydrogen 2.994 N/A GLN 207.A N LYS 203.A O no hydrogen 3.095 N/A VAL 208.A N VAL 204.A O no hydrogen 3.034 N/A THR 209.A N LEU 205.A O no hydrogen 3.268 N/A THR 209.A OG1 LYS 206.A O no hydrogen 2.433 N/A GLU 210.A N LYS 206.A O no hydrogen 3.155 N/A GLU 210.A N GLN 207.A O no hydrogen 3.102 N/A LYS 211.A N GLN 207.A O no hydrogen 3.160 N/A LYS 211.A NZ GLU 214.A OE2 no hydrogen 2.883 N/A LEU 212.A N VAL 208.A O no hydrogen 2.966 N/A LYS 213.A N THR 209.A O no hydrogen 3.220 N/A LYS 213.A N GLU 210.A O no hydrogen 3.267 N/A GLU 214.A N LYS 211.A O no hydrogen 3.172 N/A HIS 215.A ND1 LYS 211.A O no hydrogen 3.231 N/A PHE 216.A N LYS 213.A O no hydrogen 3.401 N/A ASN 218.A N LYS 213.A O no hydrogen 3.049 N/A LYS 219.A N PHE 216.A O no hydrogen 2.978 N/A LYS 219.A NZ GLU 316.A OE2 no hydrogen 3.375 N/A THR 220.A OG1 SER 314.A O no hydrogen 3.331 N/A ILE 222.A N GLU 316.A O no hydrogen 3.265 N/A PHE 223.A N ASN 255.A OD1 no hydrogen 3.309 N/A GLN 224.A N PHE 318.A O no hydrogen 3.040 N/A GLN 224.A NE2 PHE 223.A O no hydrogen 3.179 N/A ILE 233.A N ASP 230.A O no hydrogen 2.882 N/A THR 234.A N ASP 230.A O no hydrogen 3.235 N/A THR 234.A OG1 LEU 231.A O no hydrogen 3.515 N/A MET 235.A N LEU 231.A O no hydrogen 3.161 N/A HIS 236.A N CYS 247.A O no hydrogen 2.684 N/A HIS 236.A ND1 THR 141.A O no hydrogen 2.739 N/A HIS 237.A N THR 141.A OG1 no hydrogen 2.855 N/A HIS 237.A ND1 PHE 245.A O no hydrogen 2.929 N/A PHE 238.A N PHE 245.A O no hydrogen 3.189 N/A CYS 240.A N GLU 243.A O no hydrogen 2.962 N/A ARG 241.A NE ASN 295.A O no hydrogen 3.340 N/A ARG 241.A NH1 ASP 95.A OD2 no hydrogen 3.419 N/A ARG 241.A NH2 ASN 295.A O no hydrogen 3.256 N/A GLY 242.A N ASN 239.A OD1 no hydrogen 2.759 N/A GLU 243.A N CYS 240.A O no hydrogen 2.865 N/A PHE 245.A N PHE 238.A O no hydrogen 2.929 N/A TYR 246.A N LYS 270.A O no hydrogen 2.955 N/A TYR 246.A OH GLU 232.A OE2 no hydrogen 2.649 N/A CYS 247.A N HIS 236.A O no hydrogen 3.378 N/A ASN 248.A N PRO 268.A O no hydrogen 3.243 N/A THR 249.A OG1 GLN 142.A OE1 no hydrogen 2.781 N/A THR 250.A N ASN 248.A OD1 no hydrogen 3.213 N/A THR 250.A OG1 ASN 248.A OD1 no hydrogen 2.648 N/A LEU 252.A N THR 249.A O no hydrogen 3.014 N/A PHE 253.A N THR 250.A O no hydrogen 3.279 N/A ASN 255.A ND2 PHE 223.A O no hydrogen 2.609 N/A THR 256.A N ASN 254.A OD1 no hydrogen 3.000 N/A CYS 257.A N ASN 254.A O no hydrogen 2.977 N/A ILE 258.A N ASN 255.A O no hydrogen 3.328 N/A ILE 265.A N ILE 196.A O no hydrogen 2.894 N/A LEU 267.A N CYS 194.A O no hydrogen 2.548 N/A CYS 269.A N ALA 192.A O no hydrogen 2.736 N/A CYS 269.A SG LEU 267.A O no hydrogen 3.739 N/A LYS 270.A N TYR 246.A O no hydrogen 2.952 N/A ILE 271.A N ARG 190.A O no hydrogen 2.859 N/A LYS 272.A N PHE 244.A O no hydrogen 3.032 N/A GLN 273.A NE2 TYR 286.A O no hydrogen 3.519 N/A ILE 275.A N ALA 284.A O no hydrogen 3.197 N/A ASN 276.A N GLU 232.A OE2 no hydrogen 2.999 N/A ASN 276.A ND2 GLU 232.A OE1 no hydrogen 2.877 N/A MET 277.A N GLY 282.A O no hydrogen 3.312 N/A GLN 279.A N GLN 279.A OE1 no hydrogen 2.399 N/A GLY 280.A N MET 277.A O no hydrogen 2.880 N/A ALA 284.A N ILE 275.A O no hydrogen 2.985 N/A MET 285.A N VAL 77.A O no hydrogen 2.872 N/A TYR 286.A N GLN 273.A O no hydrogen 2.800 N/A ILE 290.A N GLU 243.A OE2 no hydrogen 2.965 N/A ILE 294.A N ARG 182.A O no hydrogen 3.123 N/A CYS 296.A N CYS 180.A O no hydrogen 2.826 N/A SER 298.A N ILE 178.A O no hydrogen 2.981 N/A ASN 299.A N ASN 146.A OD1 no hydrogen 3.340 N/A ILE 300.A N VAL 176.A O no hydrogen 3.016 N/A THR 301.A N LEU 144.A O no hydrogen 2.951 N/A THR 301.A OG1 LEU 144.A O no hydrogen 3.412 N/A ILE 303.A N VAL 170.A O no hydrogen 2.973 N/A LEU 304.A N GLN 142.A O no hydrogen 3.007 N/A LEU 305.A N ILE 168.A O no hydrogen 2.915 N/A THR 306.A N ARG 319.A O no hydrogen 2.710 N/A ARG 307.A NH1 GLU 316.A OE1 no hydrogen 2.801 N/A ASP 308.A N ILE 317.A O no hydrogen 2.925 N/A SER 314.A N ASN 312.A O no hydrogen 2.520 N/A SER 314.A OG ASN 312.A O no hydrogen 2.999 N/A SER 314.A OG THR 315.A OG1 no hydrogen 3.407 N/A THR 315.A OG1 SER 314.A OG no hydrogen 3.407 N/A GLU 316.A N THR 220.A O no hydrogen 3.233 N/A PHE 318.A N ILE 222.A O no hydrogen 2.939 N/A ARG 319.A N THR 306.A O no hydrogen 2.937 N/A ARG 319.A NE ASP 308.A OD1 no hydrogen 2.865 N/A ARG 319.A NE ASP 308.A OD2 no hydrogen 3.271 N/A ARG 319.A NH1 PRO 225.A O no hydrogen 2.850 N/A ARG 319.A NH2 ASP 308.A OD2 no hydrogen 2.773 N/A GLY 321.A N LEU 304.A O no hydrogen 2.976 N/A LYS 326.A N ASN 324.A OD1 no hydrogen 3.193 N/A LYS 326.A NZ GLU 59.A OE1 no hydrogen 2.789 N/A ASP 327.A N ASN 324.A O no hydrogen 3.115 N/A ASN 328.A N ILE 325.A O no hydrogen 3.054 N/A ASN 328.A ND2 VAL 138.A O no hydrogen 3.697 N/A ASN 328.A ND2 SER 140.A O no hydrogen 3.109 N/A TRP 329.A NE1 GLN 62.A OE1 no hydrogen 2.865 N/A ARG 330.A N LYS 326.A O no hydrogen 2.870 N/A SER 331.A N ASP 327.A O no hydrogen 3.201 N/A SER 331.A N ASN 328.A O no hydrogen 3.317 N/A SER 331.A OG ASN 328.A O no hydrogen 2.790 N/A GLU 332.A N TRP 329.A O no hydrogen 3.243 N/A LEU 333.A N TRP 329.A O no hydrogen 3.101 N/A TYR 336.A N LEU 333.A O no hydrogen 3.094 N/A TYR 336.A OH HIS 133.A ND1 no hydrogen 2.573 N/A LYS 337.A N LEU 110.A O no hydrogen 3.049 N/A LYS 337.A NZ ASP 4.A OD1 no hydrogen 3.308 N/A LYS 337.A NZ ASP 4.A OD2 no hydrogen 2.932 N/A LYS 337.A NZ GLU 48.A OE1 no hydrogen 2.852 N/A LYS 337.A NZ ASN 49.A O no hydrogen 3.032 N/A VAL 339.A N VAL 108.A O no hydrogen 2.998 N/A GLN 340.A N LYS 3.A O no hydrogen 2.826 N/A ILE 341.A N GLY 106.A O no hydrogen 3.183 N/A