Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4jzw_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 5.A N VAL 332.A O no hydrogen 2.984 N/A THR 8.A N THR 7.A OG1 no hydrogen 2.611 N/A THR 8.A OG1.B THR 8.A O no hydrogen 2.409 N/A LEU 9.A N GLN 60.A OE1 no hydrogen 3.161 N/A PHE 10.A N CYS 102.A O no hydrogen 3.083 N/A CYS 11.A SG ALA 30.A O no hydrogen 3.360 N/A ALA 12.A N HIS 100.A O no hydrogen 2.820 N/A SER 13.A N VAL 32.A O no hydrogen 2.918 N/A ALA 15.A N SER 13.A OG no hydrogen 2.842 N/A LYS 16.A N ASN 24.A OD1 no hydrogen 2.970 N/A LYS 16.A NZ.A ASP 14.A O no hydrogen 3.127 N/A ASP 19.A N LYS 16.A O no hydrogen 3.216 N/A GLU 21.A N ASP 19.A OD1 no hydrogen 2.943 N/A VAL 22.A N SER 93.A O no hydrogen 2.956 N/A HIS 23.A N GLU 21.A OE1 no hydrogen 3.040 N/A HIS 23.A ND1 GLU 21.A OE1 no hydrogen 2.725 N/A ASN 24.A N GLU 21.A OE2 no hydrogen 2.842 N/A ASN 24.A ND2 GLU 21.A OE2 no hydrogen 2.904 N/A VAL 25.A N GLU 21.A O no hydrogen 2.912 N/A TRP 26.A N VAL 22.A O no hydrogen 2.939 N/A ALA 27.A N HIS 23.A O no hydrogen 2.859 N/A THR 28.A N ASN 24.A O no hydrogen 2.850 N/A THR 28.A OG1.A ASN 24.A O no hydrogen 2.978 N/A THR 28.A OG1.A VAL 25.A O no hydrogen 2.391 N/A THR 28.A OG1.B LYS 16.A O no hydrogen 3.557 N/A THR 28.A OG1.B ASN 24.A O no hydrogen 2.554 N/A HIS 29.A N TRP 26.A O no hydrogen 3.181 N/A ALA 30.A N TRP 26.A O no hydrogen 2.843 N/A CYS 31.A N ALA 27.A O no hydrogen 2.848 N/A VAL 32.A N CYS 11.A O no hydrogen 2.937 N/A THR 34.A N SER 13.A O no hydrogen 3.012 N/A THR 34.A OG1.A ASP 14.A OD1 no hydrogen 2.804 N/A THR 34.A OG1.B ASP 14.A OD1 no hydrogen 2.403 N/A ASN 37.A N ASP 35.A OD1 no hydrogen 2.944 N/A GLN 39.A NE2 ASN 37.A O no hydrogen 3.687 N/A VAL 41.A N THR 128.A O no hydrogen 2.997 N/A LYS 42.A NZ ASN 125.A OD1 no hydrogen 2.622 N/A LEU 43.A N VAL 126.A O no hydrogen 2.882 N/A VAL 46.A N LEU 43.A O no hydrogen 3.438 N/A GLU 48.A N CYS 123.A O no hydrogen 2.942 N/A PHE 50.A N GLY 121.A O no hydrogen 2.891 N/A MET 52.A N GLY 119.A O no hydrogen 2.832 N/A TRP 53.A N ASN 51.A OD1 no hydrogen 3.036 N/A LYS 54.A N ASN 51.A O no hydrogen 3.115 N/A MET 57.A N ASN 55.A OD1 no hydrogen 3.154 N/A VAL 58.A N ASN 55.A O no hydrogen 2.896 N/A GLN 60.A N ASN 56.A O no hydrogen 2.968 N/A GLN 60.A NE2 THR 7.A O no hydrogen 2.410 N/A GLN 60.A NE2 ASN 56.A OD1 no hydrogen 2.763 N/A MET 61.A N MET 57.A O no hydrogen 2.980 N/A HIS 62.A N VAL 58.A O no hydrogen 2.971 N/A GLU 63.A N GLU 59.A O no hydrogen 3.035 N/A ASP 64.A N GLN 60.A O no hydrogen 3.017 N/A ILE 65.A N MET 61.A O no hydrogen 2.932 N/A ILE 66.A N HIS 62.A O no hydrogen 2.909 N/A SER 67.A N GLU 63.A O no hydrogen 3.035 N/A SER 67.A OG.A ASP 64.A O no hydrogen 2.740 N/A SER 67.A OG.B GLU 63.A O no hydrogen 2.892 N/A LEU 68.A N ASP 64.A O no hydrogen 2.870 N/A TRP 69.A N ILE 65.A O no hydrogen 2.951 N/A ASP 70.A N ILE 66.A O no hydrogen 2.788 N/A GLN 71.A N SER 67.A O no hydrogen 2.931 N/A SER 72.A N TRP 69.A O no hydrogen 3.094 N/A SER 72.A OG LEU 68.A O no hydrogen 2.381 N/A LEU 73.A N TRP 69.A O no hydrogen 2.788 N/A LYS 74.A NZ ASP 70.A O no hydrogen 2.807 N/A CYS 76.A N MET 282.A O no hydrogen 2.753 N/A VAL 77.A N MET 282.A O no hydrogen 3.395 N/A LYS 78.A N ILE 85.A O no hydrogen 2.805 N/A LEU 79.A N LYS 280.A O no hydrogen 2.772 N/A THR 80.A N SER 83.A O no hydrogen 3.167 N/A SER 83.A N THR 80.A O no hydrogen 3.081 N/A SER 83.A OG THR 80.A O no hydrogen 2.514 N/A ILE 85.A N LYS 78.A O no hydrogen 2.927 N/A THR 86.A OG1.A CYS 76.A O no hydrogen 2.550 N/A GLN 87.A N CYS 76.A O no hydrogen 3.063 N/A GLN 87.A NE2 PRO 75.A O no hydrogen 3.078 N/A LYS 91.A NZ GLU 242.A OE1 no hydrogen 3.425 N/A LYS 91.A NZ GLU 242.A OE2 no hydrogen 2.898 N/A LYS 91.A NZ ALA 284.A O no hydrogen 2.882 N/A GLU 95.A N GLU 21.A OE1 no hydrogen 2.749 N/A ILE 99.A N ILE 135.A O no hydrogen 2.820 N/A HIS 100.A N ALA 12.A O no hydrogen 2.821 N/A HIS 100.A ND1 THR 132.A O no hydrogen 2.863 N/A TYR 101.A N THR 132.A OG1 no hydrogen 2.899 N/A TYR 101.A OH ASP 64.A OD2 no hydrogen 2.646 N/A CYS 102.A N PHE 10.A O no hydrogen 2.729 N/A ALA 103.A N GLN 130.A O no hydrogen 3.294 N/A PHE 107.A N PRO 104.A O no hydrogen 3.146 N/A ALA 108.A N VAL 333.A O no hydrogen 2.911 N/A LEU 110.A N LYS 331.A O no hydrogen 2.821 N/A LYS 111.A N SER 127.A O no hydrogen 2.803 N/A CYS 112.A N LYS 329.A O no hydrogen 2.740 N/A ASN 113.A N ASN 125.A O no hydrogen 2.889 N/A ASN 113.A ND2 ASN 125.A O no hydrogen 3.233 N/A ASN 113.A ND2 SER 127.A OG no hydrogen 3.019 N/A LYS 116.A NZ GLU 153.A OE1 no hydrogen 3.244 N/A THR 120.A N ASN 118.A OD1 no hydrogen 3.035 N/A GLY 121.A N PHE 50.A O no hydrogen 2.952 N/A CYS 123.A N GLU 48.A O no hydrogen 2.823 N/A CYS 123.A SG ASN 125.A O no hydrogen 3.628 N/A THR 124.A N ASP 114.A OD2 no hydrogen 2.887 N/A THR 124.A OG1 ASP 114.A OD1 no hydrogen 3.420 N/A SER 127.A N LYS 111.A O no hydrogen 3.031 N/A SER 127.A OG GLU 40.A OE2 no hydrogen 2.652 N/A THR 128.A N VAL 41.A O no hydrogen 2.841 N/A THR 128.A OG1.A ILE 109.A O no hydrogen 3.464 N/A VAL 129.A N ILE 109.A O no hydrogen 3.065 N/A GLN 130.A NE2 ASP 35.A OD2 no hydrogen 2.581 N/A GLN 130.A NE2 ASN 37.A O no hydrogen 3.341 N/A THR 132.A N TYR 101.A O no hydrogen 2.799 N/A THR 132.A OG1 HIS 133.A O no hydrogen 2.901 N/A HIS 133.A N TYR 330.A OH no hydrogen 3.093 N/A HIS 133.A ND1 TYR 330.A OH no hydrogen 2.730 N/A HIS 133.A NE2 GLU 326.A OE1 no hydrogen 2.787 N/A ILE 135.A N ILE 99.A O no hydrogen 2.797 N/A ARG 136.A NH1 PRO 96.A O no hydrogen 3.218 N/A VAL 138.A N ARG 136.A O no hydrogen 2.862 N/A SER 140.A OG LEU 143.A O no hydrogen 2.702 N/A THR 141.A N SER 236.A O no hydrogen 2.998 N/A THR 141.A OG1 GLU 231.A O no hydrogen 2.777 N/A THR 141.A OG1 THR 234.A O no hydrogen 2.945 N/A THR 141.A OG1 SER 236.A OG no hydrogen 3.429 N/A GLN 142.A NE2 ILE 232.A O no hydrogen 2.889 N/A GLN 142.A NE2 VAL 233.A O no hydrogen 2.955 N/A LEU 143.A N THR 141.A O no hydrogen 2.696 N/A LEU 144.A N GLY 299.A O no hydrogen 2.854 N/A ASN 146.A N ASN 296.A O no hydrogen 2.732 N/A GLY 147.A N THR 298.A OG1 no hydrogen 2.984 N/A SER 148.A N GLU 326.A OE2 no hydrogen 2.759 N/A SER 148.A OG HIS 133.A NE2 no hydrogen 3.230 N/A SER 148.A OG GLU 326.A OE1 no hydrogen 2.740 N/A ALA 150.A N LEU 172.A O no hydrogen 2.758 N/A VAL 155.A N GLN 171.A O no hydrogen 3.018 N/A ARG 157.A N ILE 169.A O no hydrogen 2.987 N/A ARG 157.A NE PHE 117.A O no hydrogen 2.769 N/A ARG 157.A NH1 GLN 171.A OE1 no hydrogen 2.939 N/A ARG 157.A NH2 PHE 117.A O no hydrogen 2.879 N/A ARG 157.A NH2 GLN 171.A OE1 no hydrogen 3.433 N/A ASN 160.A N SER 158.A OG no hydrogen 2.986 N/A THR 162.A N ASN 160.A OD1 no hydrogen 2.976 N/A THR 162.A OG1 ASN 160.A OD1 no hydrogen 2.744 N/A ASN 163.A N ASN 160.A O no hydrogen 3.106 N/A ASN 164.A ND2 ASP 305.A O no hydrogen 3.003 N/A ALA 165.A N ASN 163.A OD1 no hydrogen 2.883 N/A LYS 166.A N ASN 163.A O no hydrogen 2.956 N/A LYS 166.A NZ GLU 159.A OE1 no hydrogen 2.943 N/A ILE 168.A N LEU 302.A O no hydrogen 2.834 N/A ILE 169.A N ARG 157.A O no hydrogen 2.805 N/A VAL 170.A N LEU 300.A O no hydrogen 2.751 N/A GLN 171.A N VAL 155.A O no hydrogen 2.800 N/A GLN 171.A NE2 SER 148.A O no hydrogen 3.610 N/A GLN 171.A NE2 TYR 328.A OH no hydrogen 3.371 N/A LEU 172.A N THR 298.A O no hydrogen 3.028 N/A VAL 176.A N ILE 297.A O no hydrogen 3.128 N/A ILE 178.A N SER 295.A O no hydrogen 2.820 N/A ASN 179.A N ASN 193.A O no hydrogen 2.965 N/A CYS 180.A N CYS 293.A O no hydrogen 2.858 N/A THR 181.A N HIS 191.A O no hydrogen 2.703 N/A ARG 182.A N ILE 291.A O no hydrogen 2.716 N/A ARG 182.A NE PRO 183.A O no hydrogen 3.021 N/A ARG 182.A NH1 ILE 187.A O no hydrogen 2.708 N/A ARG 182.A NH1 ILE 287.A O no hydrogen 3.402 N/A ARG 182.A NH2 ILE 287.A O no hydrogen 2.685 N/A ARG 182.A NH2 GLY 289.A O no hydrogen 2.617 N/A ARG 188.A N ASP 186.A OD1 no hydrogen 2.977 N/A ARG 188.A NE GLN 270.A OE1 no hydrogen 3.359 N/A ARG 188.A NH2 GLN 270.A OE1 no hydrogen 2.696 N/A GLN 189.A N ASP 186.A O no hydrogen 3.169 N/A ALA 190.A N CYS 266.A O no hydrogen 3.086 N/A HIS 191.A N THR 181.A O no hydrogen 2.918 N/A CYS 192.A N LEU 264.A O no hydrogen 2.945 N/A ASN 193.A N ASN 179.A O no hydrogen 2.737 N/A LEU 194.A N ILE 262.A O no hydrogen 2.967 N/A LYS 196.A N ARG 260.A O no hydrogen 2.995 N/A THR 197.A OG1 SER 195.A OG no hydrogen 3.284 N/A GLN 198.A N SER 195.A OG no hydrogen 3.171 N/A TRP 199.A N SER 195.A O no hydrogen 3.014 N/A TRP 199.A NE1 LEU 251.A O no hydrogen 2.847 N/A GLU 200.A N LYS 196.A O no hydrogen 2.840 N/A ASN 201.A N THR 197.A O no hydrogen 2.866 N/A THR 202.A N GLN 198.A O no hydrogen 2.966 N/A THR 202.A OG1 GLN 198.A O no hydrogen 2.825 N/A LEU 203.A N TRP 199.A O no hydrogen 2.972 N/A GLU 204.A N GLU 200.A O no hydrogen 2.964 N/A GLN 205.A N ASN 201.A O no hydrogen 3.075 N/A ILE 206.A N THR 202.A O no hydrogen 2.941 N/A ALA 207.A N LEU 203.A O no hydrogen 2.833 N/A ILE 208.A N GLU 204.A O no hydrogen 3.184 N/A LYS 209.A N GLN 205.A O no hydrogen 3.286 N/A LYS 209.A NZ GLU 212.A OE2 no hydrogen 3.005 N/A LEU 210.A N ILE 206.A O no hydrogen 2.775 N/A LYS 211.A N ALA 207.A O no hydrogen 2.864 N/A LYS 211.A NZ ASN 216.A O no hydrogen 3.033 N/A GLU 212.A N ILE 208.A O no hydrogen 2.988 N/A GLN 213.A N LYS 209.A O no hydrogen 3.293 N/A PHE 214.A N LEU 210.A O no hydrogen 2.793 N/A GLY 215.A N LYS 211.A O no hydrogen 2.765 N/A LYS 218.A N GLY 215.A O no hydrogen 2.987 N/A LYS 218.A NZ GLU 310.A OE2 no hydrogen 3.448 N/A THR 219.A N GLY 308.A O no hydrogen 2.942 N/A ILE 221.A N GLU 310.A O no hydrogen 2.948 N/A PHE 222.A N TRP 254.A O no hydrogen 3.017 N/A ASN 223.A N PHE 312.A O no hydrogen 2.854 N/A GLY 227.A N SER 225.A OG no hydrogen 3.154 N/A GLU 231.A N GLU 231.A OE2 no hydrogen 2.768 N/A ILE 232.A N ASP 229.A O no hydrogen 3.005 N/A VAL 233.A N ASP 229.A O no hydrogen 3.034 N/A THR 234.A N PRO 230.A O no hydrogen 2.976 N/A THR 234.A OG1 PRO 230.A O no hydrogen 2.822 N/A HIS 235.A N CYS 246.A O no hydrogen 2.837 N/A HIS 235.A ND1 THR 141.A O no hydrogen 2.840 N/A SER 236.A N THR 141.A OG1 no hydrogen 3.143 N/A SER 236.A OG THR 141.A OG1 no hydrogen 3.429 N/A SER 236.A OG GLU 231.A O no hydrogen 2.861 N/A PHE 237.A N PHE 244.A O no hydrogen 3.127 N/A CYS 239.A N GLU 242.A O no hydrogen 2.945 N/A GLY 241.A N ASN 238.A OD1 no hydrogen 2.770 N/A GLU 242.A N CYS 239.A O no hydrogen 3.019 N/A PHE 244.A N PHE 237.A O no hydrogen 2.837 N/A TYR 245.A N ARG 267.A O no hydrogen 2.819 N/A TYR 245.A OH GLU 231.A OE1 no hydrogen 2.706 N/A CYS 246.A N HIS 235.A O no hydrogen 2.814 N/A ASN 247.A N PRO 265.A O no hydrogen 2.935 N/A SER 248.A OG GLN 142.A OE1 no hydrogen 2.655 N/A THR 249.A N ASN 247.A OD1 no hydrogen 3.041 N/A THR 249.A OG1 ASN 247.A OD1 no hydrogen 2.861 N/A GLN 250.A NE2 THR 263.A O no hydrogen 2.772 N/A LEU 251.A N SER 248.A O no hydrogen 2.893 N/A PHE 252.A N SER 248.A O no hydrogen 3.224 N/A PHE 252.A N THR 249.A O no hydrogen 3.174 N/A THR 253.A OG1 THR 249.A O no hydrogen 2.785 N/A TRP 254.A N PHE 222.A O no hydrogen 3.157 N/A THR 257.A N ASN 255.A OD1 no hydrogen 3.328 N/A THR 257.A OG1 ASN 255.A OD1 no hydrogen 3.132 N/A ARG 258.A NH1 THR 253.A O no hydrogen 3.335 N/A ILE 262.A N LEU 194.A O no hydrogen 2.768 N/A THR 263.A OG1 ASN 193.A OD1 no hydrogen 2.737 N/A LEU 264.A N CYS 192.A O no hydrogen 2.704 N/A CYS 266.A N ALA 190.A O no hydrogen 2.809 N/A CYS 266.A SG LEU 264.A O no hydrogen 3.593 N/A ARG 267.A N TYR 245.A O no hydrogen 2.911 N/A ARG 267.A NH1 ASP 186.A OD2 no hydrogen 2.847 N/A ARG 267.A NH2 ASP 186.A OD2 no hydrogen 3.227 N/A ILE 268.A N ARG 188.A O no hydrogen 2.837 N/A LYS 269.A N PHE 243.A O no hydrogen 2.992 N/A GLN 270.A NE2 TYR 283.A O no hydrogen 2.831 N/A ILE 272.A N ALA 281.A O no hydrogen 2.830 N/A ASN 273.A N GLU 231.A OE1 no hydrogen 2.908 N/A ASN 273.A ND2 GLU 231.A OE1 no hydrogen 3.530 N/A ASN 273.A ND2 GLU 231.A OE2 no hydrogen 2.906 N/A MET 274.A N GLY 279.A O no hydrogen 2.896 N/A GLN 276.A N GLN 276.A OE1 no hydrogen 2.862 N/A GLN 276.A NE2 ASP 70.A OD1 no hydrogen 3.118 N/A LYS 280.A N LEU 79.A O no hydrogen 2.903 N/A ALA 281.A N ILE 272.A O no hydrogen 2.938 N/A MET 282.A N VAL 77.A O no hydrogen 2.886 N/A TYR 283.A N GLN 270.A O no hydrogen 2.839 N/A TYR 283.A OH LEU 73.A O no hydrogen 3.374 N/A ILE 287.A N GLU 242.A OE2 no hydrogen 3.267 N/A ILE 291.A N ARG 182.A O no hydrogen 3.004 N/A CYS 293.A N CYS 180.A O no hydrogen 2.896 N/A SER 294.A OG ASN 179.A OD1 no hydrogen 2.542 N/A SER 295.A N ILE 178.A O no hydrogen 2.890 N/A ASN 296.A N ASN 146.A OD1 no hydrogen 3.042 N/A ILE 297.A N VAL 176.A O no hydrogen 2.801 N/A THR 298.A N LEU 144.A O no hydrogen 2.898 N/A THR 298.A OG1 LEU 144.A O no hydrogen 3.488 N/A GLY 299.A N LEU 144.A O no hydrogen 3.262 N/A LEU 300.A N VAL 170.A O no hydrogen 2.995 N/A LEU 301.A N GLN 142.A O no hydrogen 2.930 N/A LEU 302.A N ILE 168.A O no hydrogen 2.873 N/A THR 303.A N ARG 313.A O no hydrogen 2.828 N/A ARG 304.A NH1 GLU 310.A OE1 no hydrogen 2.977 N/A ARG 304.A NH2 PHE 161.A O no hydrogen 3.116 N/A ASP 305.A N ILE 311.A O no hydrogen 2.981 N/A THR 309.A OG1 THR 219.A OG1 no hydrogen 2.880 N/A GLU 310.A N THR 219.A O no hydrogen 3.007 N/A PHE 312.A N ILE 221.A O no hydrogen 2.750 N/A ARG 313.A N THR 303.A O no hydrogen 2.838 N/A ARG 313.A NE ASP 305.A OD1 no hydrogen 2.776 N/A ARG 313.A NE ASP 305.A OD2 no hydrogen 3.263 N/A ARG 313.A NH1 PRO 224.A O no hydrogen 2.892 N/A ARG 313.A NH2 ASP 305.A OD2 no hydrogen 2.873 N/A GLY 315.A N LEU 301.A O no hydrogen 2.685 N/A ARG 320.A N ASP 318.A OD1 no hydrogen 3.041 N/A ARG 320.A NE GLU 59.A OE1 no hydrogen 3.047 N/A ARG 320.A NH1 ASP 318.A OD1 no hydrogen 2.824 N/A ASP 321.A N ASP 318.A O no hydrogen 3.176 N/A ASN 322.A ND2 VAL 138.A O no hydrogen 3.439 N/A ASN 322.A ND2 SER 140.A O no hydrogen 3.137 N/A TRP 323.A N MET 319.A O no hydrogen 3.085 N/A TRP 323.A NE1 HIS 62.A ND1 no hydrogen 3.116 N/A ARG 324.A N ARG 320.A O no hydrogen 2.840 N/A ARG 324.A NE ASP 321.A OD1 no hydrogen 3.057 N/A ARG 324.A NH1 MET 52.A O no hydrogen 2.865 N/A SER 325.A N ASP 321.A O no hydrogen 2.922 N/A SER 325.A N ASN 322.A O no hydrogen 3.187 N/A SER 325.A OG ASN 322.A O no hydrogen 2.624 N/A GLU 326.A N TRP 323.A O no hydrogen 3.009 N/A LEU 327.A N TRP 323.A O no hydrogen 2.889 N/A TYR 330.A N LEU 327.A O no hydrogen 2.923 N/A TYR 330.A OH HIS 133.A ND1 no hydrogen 2.730 N/A LYS 331.A N LEU 110.A O no hydrogen 3.028 N/A LYS 331.A NZ GLU 48.A OE2 no hydrogen 2.741 N/A LYS 331.A NZ ASN 49.A O no hydrogen 2.731 N/A VAL 333.A N ALA 108.A O no hydrogen 2.951 N/A LYS 334.A N LYS 3.A O no hydrogen 2.875 N/A ILE 335.A N GLY 106.A O no hydrogen 2.867 N/A