Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4k4k_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 9.A N ILE 60.A O no hydrogen 2.846 N/A GLU 10.A N PRO 115.A O no hydrogen 2.923 N/A THR 12.A N VAL 117.A O no hydrogen 3.035 N/A SER 13.A N GLY 50.A O no hydrogen 3.069 N/A SER 13.A OG GLU 48.A O no hydrogen 2.667 N/A SER 13.A OG GLY 50.A O no hydrogen 3.493 N/A THR 17.A N THR 46.A O no hydrogen 2.895 N/A THR 17.A OG1 THR 46.A O no hydrogen 3.009 N/A TRP 18.A N THR 46.A O no hydrogen 3.041 N/A TRP 18.A NE1 SER 13.A OG no hydrogen 2.873 N/A GLU 19.A N ASP 22.A OD2 no hydrogen 3.097 N/A GLY 21.A N THR 43.A O no hydrogen 2.853 N/A ASP 22.A N GLU 19.A O no hydrogen 2.948 N/A ILE 24.A N TYR 41.A O no hydrogen 2.806 N/A GLY 25.A N TYR 74.A O no hydrogen 3.059 N/A ILE 26.A N ARG 39.A O no hydrogen 2.926 N/A TYR 27.A N VAL 72.A O no hydrogen 2.951 N/A TYR 27.A OH ASN 85.A OD1 no hydrogen 2.771 N/A ASN 29.A N ALA 32.A O no hydrogen 2.836 N/A ALA 32.A N ASN 29.A O no hydrogen 3.051 N/A ASN 38.A ND2 ARG 78.A O no hydrogen 2.845 N/A ARG 39.A N ILE 26.A O no hydrogen 2.812 N/A ARG 39.A NE.A ASN 36.A O no hydrogen 2.720 N/A ARG 39.A NE.B GLY 37.A O no hydrogen 2.843 N/A ARG 39.A NH1.A GLN 58.A O no hydrogen 3.428 N/A ARG 39.A NH2.B GLY 37.A O no hydrogen 3.041 N/A LYS 40.A N GLN 58.A OE1.A no hydrogen 3.062 N/A LYS 40.A N GLN 58.A OE1.B no hydrogen 2.696 N/A TYR 41.A N ILE 24.A O no hydrogen 2.988 N/A THR 42.A N THR 53.A O no hydrogen 2.836 N/A THR 43.A N ASP 22.A O no hydrogen 2.980 N/A THR 43.A OG1 GLN 45.A O no hydrogen 3.467 N/A THR 43.A OG1 SER 51.A O no hydrogen 2.892 N/A GLN 45.A N THR 43.A OG1 no hydrogen 3.304 N/A THR 46.A OG1 ASP 15.A O no hydrogen 3.256 N/A GLY 50.A N ALA 47.A O no hydrogen 3.080 N/A SER 51.A N GLN 45.A OE1 no hydrogen 3.247 N/A PHE 52.A N ALA 11.A O no hydrogen 2.836 N/A THR 53.A N THR 42.A O no hydrogen 2.777 N/A THR 53.A OG1.B THR 42.A O no hydrogen 3.506 N/A ALA 55.A N LYS 40.A O no hydrogen 2.888 N/A GLN 58.A N ALA 55.A O no hydrogen 2.971 N/A ILE 60.A N TYR 41.A OH no hydrogen 3.007 N/A PHE 62.A N VAL 7.A O no hydrogen 2.821 N/A ALA 66.A N PRO 63.A O no hydrogen 3.104 N/A SER 67.A N ASP 65.A OD1 no hydrogen 2.948 N/A SER 67.A OG ASP 65.A OD1 no hydrogen 2.648 N/A GLN 68.A NE2.A ASP 111.A OD2 no hydrogen 3.067 N/A ARG 69.A N LYS 110.A O no hydrogen 2.862 N/A ARG 69.A NE ASP 34.A OD2 no hydrogen 2.722 N/A ARG 69.A NH1 SER 67.A OG no hydrogen 2.994 N/A ARG 69.A NH1 GLN 68.A O no hydrogen 2.808 N/A ARG 69.A NH2 ASP 34.A OD2 no hydrogen 3.353 N/A ASP 70.A N LEU 28.A O no hydrogen 2.909 N/A PHE 71.A N VAL 107.A O no hydrogen 2.851 N/A VAL 72.A N TYR 27.A O no hydrogen 3.136 N/A TYR 74.A N GLY 25.A O no hydrogen 3.081 N/A TYR 74.A OH ASN 38.A OD1 no hydrogen 2.598 N/A TYR 75.A OH LYS 98.A O no hydrogen 3.312 N/A TYR 77.A N ALA 23.A O no hydrogen 3.010 N/A TYR 77.A OH GLU 79.A OE1.A no hydrogen 2.655 N/A ARG 78.A N TYR 74.A OH no hydrogen 2.983 N/A ARG 78.A NH1 THR 88.A O no hydrogen 2.794 N/A ARG 78.A NH1 THR 88.A OG1 no hydrogen 3.153 N/A ARG 78.A NH2 THR 88.A O no hydrogen 2.817 N/A ALA 82.A N VAL 86.A O no hydrogen 2.810 N/A VAL 86.A N ALA 82.A O no hydrogen 2.969 N/A TYR 87.A N TYR 160.A O no hydrogen 2.812 N/A VAL 89.A N ALA 158.A O no hydrogen 2.744 N/A VAL 91.A N THR 156.A O no hydrogen 2.970 N/A SER 92.A N ASP 90.A OD1 no hydrogen 2.948 N/A SER 92.A OG.A ASP 90.A OD1 no hydrogen 2.789 N/A SER 92.A OG.B ASP 90.A OD1 no hydrogen 2.671 N/A SER 92.A OG.B ASP 90.A OD2 no hydrogen 3.329 N/A GLN 94.A NE2 VAL 91.A O no hydrogen 2.843 N/A GLN 94.A NE2 ILE 190.A O no hydrogen 2.879 N/A GLN 97.A NE2 GLN 94.A O no hydrogen 2.880 N/A GLN 97.A NE2 GLN 94.A OE1 no hydrogen 2.981 N/A LYS 98.A NZ ASP 99.A OD1 no hydrogen 3.246 N/A ASP 99.A N PRO 96.A O no hydrogen 3.204 N/A ILE 100.A N GLN 97.A O no hydrogen 3.120 N/A LEU 102.A N ILE 100.A O no hydrogen 2.925 N/A GLY 103.A N THR 122.A O no hydrogen 3.007 N/A ALA 104.A N ALA 73.A O no hydrogen 2.906 N/A ALA 105.A N VAL 120.A O no hydrogen 3.230 N/A VAL 107.A N PHE 71.A O no hydrogen 2.910 N/A GLY 109.A N ASP 70.A OD1 no hydrogen 2.962 N/A LYS 110.A N ARG 69.A O no hydrogen 2.948 N/A LYS 110.A NZ ASP 114.A OD2 no hydrogen 2.921 N/A LYS 110.A NZ LYS 116.A O no hydrogen 3.040 N/A LYS 112.A NZ VAL 64.A O no hydrogen 3.269 N/A THR 113.A N ASP 111.A OD1 no hydrogen 2.806 N/A THR 113.A OG1 ASP 111.A OD1 no hydrogen 2.548 N/A ASP 114.A N ASP 111.A O no hydrogen 3.011 N/A VAL 117.A N GLU 10.A O no hydrogen 2.942 N/A PHE 119.A N THR 12.A O no hydrogen 2.774 N/A THR 122.A N GLY 103.A O no hydrogen 2.947 N/A THR 122.A OG1 GLY 103.A O no hydrogen 3.473 N/A HIS 123.A ND1 ASP 101.A OD1 no hydrogen 2.638 N/A LYS 124.A N LEU 102.A O no hydrogen 2.893 N/A LYS 124.A NZ GLY 166.A O no hydrogen 2.748 N/A VAL 126.A N VAL 191.A O no hydrogen 2.955 N/A LYS 127.A N SER 230.A O no hydrogen 2.983 N/A LYS 127.A NZ GLN 97.A OE1 no hydrogen 2.781 N/A LYS 127.A NZ GLU 188.A OE1 no hydrogen 2.817 N/A LEU 128.A N GLY 189.A O no hydrogen 2.795 N/A ASP 129.A N TYR 232.A O no hydrogen 2.835 N/A ILE 130.A N ALA 187.A O no hydrogen 2.782 N/A THR 131.A N TYR 234.A O no hydrogen 2.849 N/A ILE 132.A N LEU 185.A O no hydrogen 2.749 N/A LYS 133.A N ILE 236.A O no hydrogen 2.810 N/A ALA 134.A N ASP 141.A OD1 no hydrogen 2.821 N/A ASP 135.A N ILE 238.A O no hydrogen 2.957 N/A THR 137.A N ASP 135.A OD1 no hydrogen 2.970 N/A SER 138.A N ASP 135.A OD2 no hydrogen 3.375 N/A SER 138.A N THR 137.A OG1 no hydrogen 2.827 N/A SER 138.A OG ASP 135.A OD1 no hydrogen 3.312 N/A SER 138.A OG ASP 135.A OD2 no hydrogen 2.572 N/A LEU 139.A N ASP 135.A OD1 no hydrogen 2.945 N/A THR 140.A N ASP 143.A OD2 no hydrogen 2.807 N/A THR 140.A OG1 ASP 143.A OD2 no hydrogen 3.293 N/A ASP 143.A N THR 140.A O no hydrogen 2.953 N/A LEU 144.A N ASP 141.A O no hydrogen 3.005 N/A ALA 145.A N ALA 142.A O no hydrogen 3.139 N/A THR 147.A N LEU 144.A O no hydrogen 3.060 N/A THR 147.A OG1 LEU 144.A O no hydrogen 2.696 N/A THR 148.A N THR 204.A O no hydrogen 3.100 N/A THR 148.A OG1 THR 204.A OG1.B no hydrogen 2.306 N/A SER 150.A N THR 202.A O no hydrogen 3.118 N/A SER 150.A OG GLU 177.A OE2 no hydrogen 2.599 N/A ILE 151.A N ILE 178.A O no hydrogen 2.873 N/A SER 152.A N ALA 200.A O no hydrogen 2.950 N/A SER 152.A OG GLY 199.A O no hydrogen 3.429 N/A SER 152.A OG ALA 200.A O no hydrogen 3.490 N/A ASN 153.A ND2 GLY 199.A O no hydrogen 2.785 N/A GLN 154.A N LYS 176.A O no hydrogen 2.844 N/A GLN 155.A NE2 GLY 173.A O no hydrogen 3.281 N/A ALA 158.A N VAL 89.A O no hydrogen 3.094 N/A THR 159.A N THR 169.A O no hydrogen 2.872 N/A TYR 160.A N TYR 87.A O no hydrogen 2.992 N/A ASN 161.A ND2 GLY 84.A O no hydrogen 3.006 N/A VAL 162.A N ASN 85.A O no hydrogen 2.970 N/A VAL 163.A N ASN 161.A OD1 no hydrogen 2.952 N/A THR 164.A N ASN 161.A OD1 no hydrogen 2.916 N/A GLY 165.A N ASN 161.A O no hydrogen 2.947 N/A THR 169.A N THR 159.A O no hydrogen 2.749 N/A THR 171.A N ALA 157.A O no hydrogen 2.995 N/A THR 171.A OG1 ALA 157.A O no hydrogen 3.323 N/A GLY 173.A N GLN 155.A OE1 no hydrogen 2.822 N/A THR 174.A OG1 THR 175.A O no hydrogen 3.556 N/A LYS 176.A N GLN 154.A O no hydrogen 2.813 N/A LYS 176.A NZ.A SER 92.A O no hydrogen 3.103 N/A LYS 176.A NZ.B SER 92.A OG.A no hydrogen 2.831 N/A ILE 178.A N ILE 151.A O no hydrogen 2.784 N/A LEU 180.A N VAL 149.A O no hydrogen 2.841 N/A HIS 181.A N GLU 188.A O no hydrogen 3.019 N/A HIS 181.A ND1.A GLU 188.A OE2 no hydrogen 2.786 N/A ASP 183.A N LYS 186.A O no hydrogen 2.845 N/A LYS 186.A N ASP 183.A O no hydrogen 3.296 N/A ALA 187.A N ILE 130.A O no hydrogen 2.855 N/A GLU 188.A N HIS 181.A O no hydrogen 2.905 N/A GLY 189.A N LEU 128.A O no hydrogen 3.017 N/A ILE 190.A N GLN 94.A OE1 no hydrogen 2.889 N/A VAL 191.A N VAL 126.A O no hydrogen 2.827 N/A ALA 194.A N PHE 226.A O no hydrogen 2.950 N/A THR 197.A N LYS 224.A O no hydrogen 2.990 N/A THR 197.A OG1 ASN 218.A OD1 no hydrogen 3.143 N/A THR 197.A OG1 SER 223.A O no hydrogen 2.621 N/A ALA 198.A N SER 196.A OG no hydrogen 3.155 N/A LEU 201.A N TRP 215.A O no hydrogen 2.843 N/A THR 202.A N SER 150.A O no hydrogen 2.872 N/A THR 202.A OG1 HIS 214.A ND1 no hydrogen 2.965 N/A PHE 203.A N PHE 213.A O no hydrogen 2.788 N/A THR 204.A N THR 148.A O no hydrogen 3.093 N/A THR 204.A OG1.B THR 148.A OG1 no hydrogen 2.306 N/A VAL 205.A N GLN 211.A O no hydrogen 2.861 N/A LEU 208.A N VAL 205.A O no hydrogen 3.226 N/A GLY 210.A N PRO 206.A O no hydrogen 3.307 N/A GLN 211.A N LEU 208.A O no hydrogen 3.082 N/A PHE 213.A N PHE 203.A O no hydrogen 2.857 N/A HIS 214.A ND1 THR 202.A OG1 no hydrogen 2.965 N/A TRP 215.A N LEU 201.A O no hydrogen 2.940 N/A SER 219.A N ASP 216.A O no hydrogen 2.968 N/A SER 219.A OG ASP 216.A O no hydrogen 2.736 N/A ALA 220.A N VAL 217.A O no hydrogen 3.183 N/A GLN 222.A N SER 247.A OG no hydrogen 3.398 N/A SER 223.A OG VAL 217.A O no hydrogen 3.053 N/A SER 223.A OG TYR 234.A OH no hydrogen 2.764 N/A LYS 224.A NZ ASN 218.A O no hydrogen 2.712 N/A PHE 226.A N ALA 194.A O no hydrogen 2.797 N/A VAL 227.A N TYR 232.A OH no hydrogen 2.794 N/A GLY 229.A N LEU 125.A O no hydrogen 2.813 N/A SER 230.A N VAL 227.A O no hydrogen 3.233 N/A SER 230.A OG VAL 227.A O no hydrogen 2.858 N/A LYS 231.A N GLU 250.A O no hydrogen 2.812 N/A TYR 232.A N LYS 127.A O no hydrogen 2.817 N/A LEU 233.A N LYS 248.A O no hydrogen 2.755 N/A TYR 234.A N ASP 129.A O no hydrogen 2.808 N/A TYR 234.A OH SER 223.A OG no hydrogen 2.764 N/A THR 235.A N SER 246.A O no hydrogen 2.929 N/A ILE 236.A N THR 131.A O no hydrogen 2.775 N/A THR 237.A N GLU 244.A O no hydrogen 2.807 N/A ILE 238.A N LYS 133.A O no hydrogen 2.864 N/A SER 239.A N GLY 242.A O no hydrogen 2.902 N/A SER 239.A OG GLY 242.A O no hydrogen 2.881 N/A LYS 240.A N SER 138.A OG no hydrogen 2.946 N/A GLY 242.A N SER 239.A O no hydrogen 3.141 N/A GLU 244.A N THR 237.A O no hydrogen 3.011 N/A SER 246.A N THR 235.A O no hydrogen 3.016 N/A LYS 248.A N LEU 233.A O no hydrogen 2.899 N/A GLU 250.A N LYS 231.A O no hydrogen 2.915 N/A TRP 252.A N GLY 229.A O no hydrogen 2.841 N/A THR 253.A OG1 ASP 251.A O no hydrogen 3.559 N/A