Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4k8s_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 4.A N SER 1.A O no hydrogen 3.460 N/A MET 5.A N PHE 2.A O no hydrogen 2.997 N/A VAL 6.A N VAL 3.A O no hydrogen 3.067 N/A ASP 7.A N SER 165.A OG no hydrogen 2.740 N/A ASN 8.A N MET 5.A O no hydrogen 3.296 N/A ASN 8.A ND2 HIS 92.A O no hydrogen 3.049 N/A ASN 8.A ND2 MET 166.A O no hydrogen 2.974 N/A LEU 9.A N GLY 164.A O no hydrogen 3.087 N/A ARG 10.A N TYR 18.A O no hydrogen 3.246 N/A ARG 10.A NE LEU 9.A O no hydrogen 3.110 N/A ARG 10.A NH1 ASP 7.A OD1 no hydrogen 2.952 N/A ARG 10.A NH1 ASP 7.A OD2 no hydrogen 3.165 N/A ARG 10.A NH1 LEU 9.A O no hydrogen 3.307 N/A LYS 12.A NZ GLY 115.A O no hydrogen 2.921 N/A GLN 15.A N LYS 12.A O no hydrogen 3.041 N/A TYR 17.A OH CYS 158.A O no hydrogen 2.907 N/A TYR 17.A OH GLU 325.A OE1 no hydrogen 2.597 N/A TYR 18.A N ARG 10.A O no hydrogen 2.931 N/A VAL 19.A N ILE 32.A O no hydrogen 2.883 N/A MET 21.A N LEU 30.A O no hydrogen 2.918 N/A THR 22.A N SER 89.A O no hydrogen 2.817 N/A VAL 23.A N GLN 28.A O no hydrogen 2.927 N/A GLY 24.A N LEU 87.A O no hydrogen 2.643 N/A SER 25.A N SER 60.A OG no hydrogen 3.191 N/A SER 25.A N THR 62.A OG1 no hydrogen 3.038 N/A SER 25.A OG THR 62.A OG1 no hydrogen 2.500 N/A GLN 28.A N VAL 23.A O no hydrogen 2.971 N/A GLN 28.A NE2 GLN 56.A O no hydrogen 3.037 N/A LEU 30.A N MET 21.A O no hydrogen 3.038 N/A ASN 31.A N GLU 119.A OE2 no hydrogen 3.095 N/A ASN 31.A ND2 ASN 117.A O no hydrogen 2.736 N/A ILE 32.A N VAL 19.A O no hydrogen 2.822 N/A LEU 33.A N GLY 120.A O no hydrogen 2.929 N/A VAL 34.A N TYR 17.A O no hydrogen 3.014 N/A ASP 35.A N LEU 122.A O no hydrogen 3.078 N/A THR 36.A N SER 221.A OG no hydrogen 2.971 N/A THR 36.A OG1 VAL 219.A O no hydrogen 2.767 N/A GLY 37.A N ASP 35.A OD1 no hydrogen 2.812 N/A SER 38.A OG ASP 35.A OD2 no hydrogen 2.724 N/A SER 39.A OG TYR 126.A O no hydrogen 2.861 N/A ASN 40.A ND2 ARG 131.A O no hydrogen 2.822 N/A ALA 42.A N ILE 121.A O no hydrogen 2.901 N/A VAL 43.A N ALA 103.A O no hydrogen 2.952 N/A GLY 44.A N GLU 119.A O no hydrogen 2.785 N/A ALA 45.A N ILE 105.A O no hydrogen 3.080 N/A PHE 50.A N HIS 48.A ND1 no hydrogen 3.261 N/A LEU 51.A N HIS 48.A O no hydrogen 3.014 N/A ARG 53.A NH1 THR 29.A O no hydrogen 3.425 N/A TYR 55.A N GLY 44.A O no hydrogen 2.891 N/A TYR 55.A OH ASP 86.A OD2 no hydrogen 2.552 N/A GLN 56.A N GLN 28.A OE1 no hydrogen 3.025 N/A ARG 57.A NH1 TYR 63.A OH no hydrogen 3.167 N/A ARG 57.A NH2 GLU 82.A OE1 no hydrogen 2.998 N/A LEU 59.A N GLN 56.A O no hydrogen 3.187 N/A SER 60.A N ARG 57.A O no hydrogen 3.317 N/A SER 60.A OG ASP 86.A OD1 no hydrogen 3.334 N/A SER 60.A OG ASP 86.A OD2 no hydrogen 2.874 N/A SER 61.A N SER 25.A O no hydrogen 3.148 N/A SER 61.A OG SER 25.A O no hydrogen 3.110 N/A THR 62.A OG1 SER 25.A OG no hydrogen 2.500 N/A THR 62.A OG1 SER 60.A OG no hydrogen 2.769 N/A THR 62.A OG1 ASP 86.A OD1 no hydrogen 2.675 N/A TYR 63.A N SER 60.A O no hydrogen 3.261 N/A TYR 63.A OH ASP 65.A OD2 no hydrogen 3.042 N/A ARG 64.A N THR 85.A O no hydrogen 2.902 N/A LEU 66.A N LEU 83.A O no hydrogen 3.115 N/A ARG 67.A N ASP 65.A OD1 no hydrogen 2.632 N/A VAL 70.A N GLY 81.A O no hydrogen 2.945 N/A VAL 72.A N TRP 79.A O no hydrogen 3.098 N/A TYR 74.A N GLY 77.A O no hydrogen 2.814 N/A LYS 78.A N ASP 109.A O no hydrogen 3.148 N/A TRP 79.A N VAL 72.A O no hydrogen 3.134 N/A TRP 79.A NE1 TYR 74.A OH no hydrogen 2.948 N/A GLU 80.A N GLU 107.A O no hydrogen 2.858 N/A GLY 81.A N VAL 70.A O no hydrogen 2.937 N/A GLU 82.A N ALA 104.A O no hydrogen 2.894 N/A LEU 83.A N LYS 68.A O no hydrogen 3.066 N/A GLY 84.A N ILE 102.A O no hydrogen 3.186 N/A THR 85.A N ARG 64.A O no hydrogen 2.826 N/A ASP 86.A N ALA 100.A O no hydrogen 3.397 N/A LEU 87.A N ASP 86.A OD1 no hydrogen 2.688 N/A VAL 88.A N VAL 98.A O no hydrogen 2.808 N/A SER 89.A N THR 22.A O no hydrogen 2.794 N/A SER 89.A OG THR 22.A OG1 no hydrogen 2.746 N/A VAL 96.A N PRO 94.A O no hydrogen 2.944 N/A VAL 98.A N VAL 88.A O no hydrogen 3.030 N/A ARG 99.A NH1 THR 62.A O no hydrogen 3.117 N/A ARG 99.A NH1 THR 85.A OG1 no hydrogen 2.781 N/A ARG 99.A NH2 THR 62.A O no hydrogen 2.912 N/A ALA 100.A N ASP 86.A O no hydrogen 3.183 N/A ASN 101.A ND2 GLU 137.A O no hydrogen 3.057 N/A ILE 102.A N GLY 84.A O no hydrogen 2.899 N/A ALA 103.A N PHE 41.A O no hydrogen 2.827 N/A ALA 104.A N GLU 82.A O no hydrogen 2.676 N/A ILE 105.A N VAL 43.A O no hydrogen 2.795 N/A THR 106.A N GLU 80.A O no hydrogen 2.969 N/A THR 106.A OG1 GLU 80.A O no hydrogen 3.297 N/A GLU 107.A N GLU 80.A O no hydrogen 3.215 N/A ASP 109.A N LYS 78.A O no hydrogen 2.942 N/A LYS 110.A NZ ASP 109.A OD2 no hydrogen 3.475 N/A SER 116.A N ILE 113.A O no hydrogen 3.296 N/A ASN 117.A ND2 TYR 18.A OH no hydrogen 3.015 N/A TRP 118.A N SER 116.A OG no hydrogen 3.131 N/A TRP 118.A NE1 GLN 15.A O no hydrogen 2.927 N/A GLU 119.A N ASN 31.A O no hydrogen 2.823 N/A ILE 121.A N ALA 42.A O no hydrogen 2.840 N/A LEU 122.A N LEU 33.A O no hydrogen 2.815 N/A GLY 123.A N ASN 40.A O no hydrogen 2.802 N/A LEU 124.A N ASP 35.A O no hydrogen 2.752 N/A ALA 125.A N SER 38.A O no hydrogen 2.640 N/A TYR 126.A N TRP 189.A O no hydrogen 3.171 N/A ILE 129.A N TYR 126.A O no hydrogen 3.182 N/A ALA 130.A N ALA 127.A O no hydrogen 2.776 N/A ARG 131.A N ASN 40.A OD1 no hydrogen 3.075 N/A SER 135.A N ASP 133.A OD1 no hydrogen 2.611 N/A SER 135.A OG ASP 133.A OD1 no hydrogen 2.900 N/A LEU 136.A N ASP 133.A O no hydrogen 3.272 N/A SER 142.A N PRO 138.A O no hydrogen 3.065 N/A SER 142.A OG GLU 137.A OE2 no hydrogen 2.736 N/A SER 142.A OG PRO 138.A O no hydrogen 3.410 N/A LEU 143.A N PHE 139.A O no hydrogen 2.779 N/A VAL 144.A N PHE 140.A O no hydrogen 2.929 N/A LYS 145.A N ASP 141.A O no hydrogen 2.975 N/A GLN 146.A N SER 142.A O no hydrogen 3.005 N/A THR 147.A N LEU 143.A O no hydrogen 3.215 N/A THR 147.A OG1 LEU 143.A O no hydrogen 2.771 N/A VAL 149.A N THR 147.A OG1 no hydrogen 3.136 N/A LEU 152.A N PRO 150.A O no hydrogen 2.919 N/A PHE 153.A N PHE 331.A O no hydrogen 3.257 N/A SER 154.A N ILE 167.A O no hydrogen 2.863 N/A SER 154.A OG ILE 167.A O no hydrogen 3.529 N/A SER 154.A OG GLY 170.A O no hydrogen 2.714 N/A SER 154.A OG TYR 328.A OH no hydrogen 2.578 N/A LEU 155.A N VAL 329.A O no hydrogen 2.920 N/A GLN 156.A N SER 165.A O no hydrogen 2.854 N/A GLN 156.A NE2 LEU 175.A O no hydrogen 3.399 N/A CYS 158.A N GLY 163.A O no hydrogen 3.000 N/A VAL 162.A N GLY 11.A O no hydrogen 2.807 N/A GLY 164.A N LEU 9.A O no hydrogen 3.053 N/A SER 165.A N GLN 156.A O no hydrogen 2.957 N/A SER 165.A OG GLN 156.A OE1 no hydrogen 3.563 N/A MET 166.A N ASN 8.A OD1 no hydrogen 2.780 N/A ILE 167.A N SER 154.A O no hydrogen 3.013 N/A GLY 169.A N LEU 152.A O no hydrogen 2.818 N/A ASP 172.A N TYR 328.A OH no hydrogen 2.799 N/A SER 174.A N ASP 172.A OD1 no hydrogen 2.928 N/A SER 174.A OG ASP 172.A OD1 no hydrogen 2.987 N/A LEU 175.A N ASP 172.A O no hydrogen 3.152 N/A TYR 176.A OH HIS 173.A ND1 no hydrogen 2.851 N/A THR 177.A N VAL 342.A O no hydrogen 3.047 N/A TRP 181.A N PHE 340.A O no hydrogen 2.974 N/A THR 183.A N ILE 338.A O no hydrogen 2.930 N/A THR 183.A OG1 MET 280.A O no hydrogen 2.426 N/A ILE 185.A N LYS 336.A O no hydrogen 2.829 N/A ARG 186.A N GLU 192.A O no hydrogen 2.859 N/A ARG 186.A NH1 GLU 192.A OE2 no hydrogen 3.214 N/A ARG 186.A NH1 TYR 370.A O no hydrogen 2.734 N/A ARG 186.A NH2 TYR 370.A O no hydrogen 3.196 N/A TRP 189.A N ARG 187.A O no hydrogen 3.093 N/A TRP 189.A N TYR 190.A O no hydrogen 3.086 N/A TRP 189.A NE1 GLU 192.A OE1 no hydrogen 3.031 N/A TYR 191.A OH LEU 124.A O no hydrogen 2.776 N/A VAL 193.A N SER 217.A O no hydrogen 2.831 N/A ILE 195.A N ASN 213.A OD1 no hydrogen 2.998 N/A VAL 196.A N TYR 278.A O no hydrogen 2.732 N/A ARG 197.A NE VAL 196.A O no hydrogen 2.811 N/A ARG 197.A NH2 VAL 196.A O no hydrogen 3.245 N/A GLU 199.A N SER 276.A O no hydrogen 3.205 N/A ILE 200.A N GLN 203.A O no hydrogen 3.097 N/A ASN 201.A N VAL 274.A O no hydrogen 3.055 N/A GLN 203.A N ILE 200.A O no hydrogen 3.098 N/A LEU 205.A N VAL 198.A O no hydrogen 3.029 N/A LYS 210.A N ASP 208.A OD1 no hydrogen 3.462 N/A LYS 210.A NZ ASP 367.A O no hydrogen 2.783 N/A GLU 211.A N ASP 208.A O no hydrogen 3.040 N/A TYR 212.A N CYS 209.A O no hydrogen 2.895 N/A ASN 213.A N LYS 210.A O no hydrogen 3.083 N/A ASN 213.A ND2 ILE 195.A O no hydrogen 2.748 N/A ASN 213.A ND2 CYS 368.A O no hydrogen 2.939 N/A LYS 216.A NZ ASP 215.A OD2 no hydrogen 3.128 N/A LYS 216.A NZ THR 315.A O no hydrogen 2.687 N/A SER 217.A OG TYR 212.A O no hydrogen 3.175 N/A SER 217.A OG ASN 213.A OD1 no hydrogen 2.592 N/A ILE 218.A N THR 317.A O no hydrogen 2.939 N/A VAL 219.A N TYR 191.A O no hydrogen 3.089 N/A ASP 220.A N MET 319.A O no hydrogen 3.027 N/A SER 221.A N THR 36.A OG1 no hydrogen 3.054 N/A SER 221.A OG VAL 34.A O no hydrogen 2.917 N/A GLY 222.A N ASP 220.A OD1 no hydrogen 3.109 N/A THR 223.A N ASP 220.A O no hydrogen 3.147 N/A THR 223.A OG1 ASP 220.A OD2 no hydrogen 2.415 N/A LEU 226.A N ALA 309.A O no hydrogen 2.958 N/A ARG 227.A N VAL 318.A O no hydrogen 2.929 N/A LEU 228.A N SER 311.A O no hydrogen 2.972 N/A LYS 230.A N SER 313.A O no hydrogen 3.207 N/A LYS 231.A NZ GLU 211.A OE1 no hydrogen 3.540 N/A PHE 233.A N PRO 229.A O no hydrogen 2.714 N/A GLU 234.A N LYS 230.A O no hydrogen 2.812 N/A ALA 235.A N LYS 231.A O no hydrogen 3.023 N/A ALA 236.A N VAL 232.A O no hydrogen 2.775 N/A ALA 236.A N PHE 233.A O no hydrogen 3.005 N/A VAL 237.A N PHE 233.A O no hydrogen 2.896 N/A LYS 238.A N GLU 234.A O no hydrogen 3.050 N/A SER 239.A N ALA 235.A O no hydrogen 3.446 N/A ILE 240.A N ALA 236.A O no hydrogen 3.111 N/A LYS 241.A N VAL 237.A O no hydrogen 2.899 N/A ALA 242.A N LYS 238.A O no hydrogen 2.901 N/A ALA 243.A N SER 239.A O no hydrogen 2.969 N/A SER 244.A N LYS 241.A O no hydrogen 3.108 N/A SER 244.A OG ILE 240.A O no hydrogen 2.752 N/A SER 244.A OG LYS 241.A O no hydrogen 3.453 N/A SER 245.A N ALA 242.A O no hydrogen 3.524 N/A SER 245.A OG ALA 242.A O no hydrogen 3.047 N/A GLU 247.A N SER 244.A O no hydrogen 3.221 N/A LEU 255.A N ASP 251.A O no hydrogen 3.105 N/A GLY 256.A N PHE 253.A O no hydrogen 2.921 N/A GLN 258.A N GLY 252.A O no hydrogen 2.804 N/A VAL 260.A N TYR 306.A O no hydrogen 3.240 N/A TRP 262.A N ASP 304.A O no hydrogen 3.180 N/A GLN 263.A N GLN 263.A OE1 no hydrogen 2.621 N/A ALA 264.A N GLN 302.A O no hydrogen 3.117 N/A GLY 265.A N ASP 304.A OD2 no hydrogen 3.094 N/A THR 266.A N GLN 263.A O no hydrogen 2.765 N/A THR 266.A OG1 GLN 263.A O no hydrogen 2.560 N/A THR 267.A OG1 TYR 306.A OH no hydrogen 3.237 N/A TRP 269.A N THR 267.A O no hydrogen 2.892 N/A ILE 271.A N PRO 268.A O no hydrogen 3.280 N/A PHE 272.A N TRP 269.A O no hydrogen 3.053 N/A VAL 274.A N ASN 201.A OD1 no hydrogen 3.256 N/A ILE 275.A N ILE 292.A O no hydrogen 2.973 N/A SER 276.A N GLU 199.A O no hydrogen 3.012 N/A SER 276.A OG THR 291.A OG1 no hydrogen 3.052 N/A LEU 277.A N ILE 290.A O no hydrogen 2.903 N/A TYR 278.A N ARG 197.A O no hydrogen 3.033 N/A TYR 278.A OH GLU 199.A OE1 no hydrogen 3.266 N/A TYR 278.A OH GLU 199.A OE2 no hydrogen 2.997 N/A LEU 279.A N PHE 288.A O no hydrogen 2.902 N/A MET 280.A N ILE 194.A O no hydrogen 3.020 N/A GLY 281.A N GLN 286.A O no hydrogen 2.786 N/A GLN 286.A N VAL 283.A O no hydrogen 2.886 N/A SER 287.A N PHE 360.A O no hydrogen 2.828 N/A SER 287.A OG THR 362.A OG1 no hydrogen 2.715 N/A PHE 288.A N LEU 279.A O no hydrogen 3.205 N/A ARG 289.A N GLU 357.A O no hydrogen 2.938 N/A ARG 289.A NH1 TYR 278.A OH no hydrogen 3.139 N/A ARG 289.A NH2 GLU 357.A OE2 no hydrogen 2.307 N/A ILE 290.A N LEU 277.A O no hydrogen 2.703 N/A THR 291.A N ALA 355.A O no hydrogen 2.907 N/A THR 291.A OG1 SER 276.A OG no hydrogen 3.052 N/A ILE 292.A N ILE 275.A O no hydrogen 2.604 N/A GLN 295.A N GLN 295.A OE1 no hydrogen 2.636 N/A GLN 295.A NE2 ASP 349.A OD2 no hydrogen 2.620 N/A GLN 296.A N LEU 293.A O no hydrogen 2.834 N/A TYR 297.A N LEU 293.A O no hydrogen 3.447 N/A TYR 297.A OH PRO 273.A O no hydrogen 2.363 N/A LEU 298.A N PRO 294.A O no hydrogen 3.057 N/A ARG 299.A N LYS 307.A O no hydrogen 2.801 N/A VAL 301.A N CYS 305.A O no hydrogen 3.242 N/A ASP 304.A N TRP 262.A O no hydrogen 2.666 N/A TYR 306.A N VAL 260.A O no hydrogen 2.896 N/A TYR 306.A OH THR 267.A OG1 no hydrogen 3.237 N/A LYS 307.A N ARG 299.A O no hydrogen 2.625 N/A ALA 309.A N TYR 297.A O no hydrogen 2.913 N/A SER 311.A N LEU 226.A O no hydrogen 3.010 N/A SER 311.A OG ASN 225.A OD1 no hydrogen 2.590 N/A SER 313.A N LEU 228.A O no hydrogen 2.776 N/A SER 313.A OG GLY 316.A O no hydrogen 3.213 N/A THR 315.A N SER 313.A OG no hydrogen 2.998 N/A THR 317.A N LYS 216.A O no hydrogen 2.797 N/A THR 317.A OG1 TYR 212.A O no hydrogen 2.604 N/A VAL 318.A N ARG 227.A O no hydrogen 2.861 N/A MET 319.A N ILE 218.A O no hydrogen 2.895 N/A GLY 320.A N ASN 225.A O no hydrogen 3.278 N/A ALA 321.A N THR 223.A O no hydrogen 2.820 N/A VAL 322.A N THR 224.A O no hydrogen 3.088 N/A ILE 323.A N GLY 320.A O no hydrogen 2.812 N/A MET 324.A N GLY 320.A O no hydrogen 2.980 N/A GLU 325.A N ALA 321.A O no hydrogen 2.864 N/A PHE 327.A N MET 324.A O no hydrogen 2.901 N/A TYR 328.A N ALA 341.A O no hydrogen 2.678 N/A TYR 328.A OH SER 154.A OG no hydrogen 2.578 N/A VAL 329.A N LEU 155.A O no hydrogen 2.935 N/A VAL 330.A N GLY 339.A O no hydrogen 2.751 N/A PHE 331.A N PHE 153.A O no hydrogen 2.886 N/A ASP 332.A N ARG 337.A O no hydrogen 3.013 N/A ARG 333.A NE ASN 151.A OD1 no hydrogen 2.612 N/A ARG 333.A NH1 TYR 191.A OH no hydrogen 2.869 N/A ARG 333.A NH2 ASP 141.A OD1 no hydrogen 3.351 N/A ALA 334.A N ASN 151.A O no hydrogen 2.953 N/A ARG 335.A N ASP 332.A OD1 no hydrogen 2.995 N/A LYS 336.A N ARG 333.A O no hydrogen 3.022 N/A ARG 337.A N ASP 332.A O no hydrogen 3.102 N/A ARG 337.A NE ASP 332.A OD2 no hydrogen 2.984 N/A ARG 337.A NH1 GLU 282.A OE2 no hydrogen 2.804 N/A ARG 337.A NH2 ASP 332.A OD2 no hydrogen 3.308 N/A ILE 338.A N THR 183.A O no hydrogen 2.767 N/A GLY 339.A N VAL 330.A O no hydrogen 2.730 N/A PHE 340.A N TRP 181.A O no hydrogen 2.749 N/A ALA 341.A N TYR 328.A O no hydrogen 2.951 N/A SER 343.A N GLY 326.A O no hydrogen 3.007 N/A ALA 344.A N LEU 175.A O no hydrogen 2.959 N/A CYS 345.A N SER 343.A OG no hydrogen 3.283 N/A CYS 345.A SG SER 343.A OG no hydrogen 3.504 N/A HIS 346.A N SER 343.A O no hydrogen 3.242 N/A PHE 351.A N ASP 349.A OD1 no hydrogen 2.735 N/A ARG 352.A N ASP 349.A OD1 no hydrogen 2.954 N/A ARG 352.A NH1 PHE 272.A O no hydrogen 2.940 N/A ARG 352.A NH2 PHE 272.A O no hydrogen 2.787 N/A ALA 354.A N HIS 346.A NE2 no hydrogen 3.206 N/A GLU 357.A N ARG 289.A O no hydrogen 3.056 N/A PHE 360.A N SER 287.A O no hydrogen 2.856 N/A THR 362.A N ASN 285.A O no hydrogen 3.026 N/A THR 362.A OG1 SER 287.A OG no hydrogen 2.715 N/A CYS 368.A N MET 365.A O no hydrogen 3.037 N/A CYS 368.A SG ASP 364.A O no hydrogen 3.996 N/A GLY 369.A N GLU 366.A O no hydrogen 3.007 N/A