Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4laj_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 5.A N VAL 339.A O no hydrogen 3.262 N/A LEU 9.A N GLN 60.A OE1 no hydrogen 2.855 N/A PHE 10.A N CYS 102.A O no hydrogen 2.908 N/A CYS 11.A SG ALA 30.A O no hydrogen 3.415 N/A ALA 12.A N HIS 100.A O no hydrogen 2.851 N/A SER 13.A N VAL 32.A O no hydrogen 2.999 N/A ALA 15.A N SER 13.A OG no hydrogen 3.274 N/A LYS 16.A N ASN 24.A OD1 no hydrogen 2.951 N/A ASP 19.A N LYS 16.A O no hydrogen 3.081 N/A GLU 21.A N ASP 19.A OD1 no hydrogen 2.915 N/A VAL 22.A N SER 93.A O no hydrogen 2.842 N/A HIS 23.A N GLU 21.A OE1 no hydrogen 3.063 N/A HIS 23.A ND1 GLU 21.A OE1 no hydrogen 2.717 N/A ASN 24.A N GLU 21.A OE2 no hydrogen 2.836 N/A ASN 24.A ND2 GLU 21.A OE2 no hydrogen 2.682 N/A VAL 25.A N GLU 21.A O no hydrogen 2.949 N/A TRP 26.A N VAL 22.A O no hydrogen 2.874 N/A ALA 27.A N HIS 23.A O no hydrogen 2.823 N/A THR 28.A N ASN 24.A O no hydrogen 2.720 N/A THR 28.A OG1 ASN 24.A O no hydrogen 2.637 N/A HIS 29.A N TRP 26.A O no hydrogen 3.206 N/A ALA 30.A N TRP 26.A O no hydrogen 2.787 N/A CYS 31.A N ALA 27.A O no hydrogen 2.898 N/A VAL 32.A N CYS 11.A O no hydrogen 2.943 N/A THR 34.A OG1 ASP 14.A OD1 no hydrogen 2.217 N/A ASN 37.A N ASP 35.A OD1 no hydrogen 2.921 N/A GLN 39.A NE2 ASN 37.A O no hydrogen 3.043 N/A VAL 41.A N THR 128.A O no hydrogen 3.181 N/A LEU 43.A N VAL 126.A O no hydrogen 3.054 N/A VAL 46.A N LEU 43.A O no hydrogen 3.473 N/A GLU 48.A N CYS 123.A O no hydrogen 2.911 N/A PHE 50.A N GLY 121.A O no hydrogen 2.791 N/A MET 52.A N GLY 119.A O no hydrogen 2.863 N/A TRP 53.A N ASN 51.A OD1 no hydrogen 3.052 N/A LYS 54.A N ASN 51.A O no hydrogen 3.020 N/A ASN 55.A ND2 LEU 334.A O no hydrogen 3.503 N/A MET 57.A N ASN 55.A OD1 no hydrogen 3.303 N/A VAL 58.A N ASN 55.A O no hydrogen 2.968 N/A GLN 60.A N ASN 56.A O no hydrogen 3.075 N/A GLN 60.A NE2 THR 7.A O no hydrogen 2.756 N/A GLN 60.A NE2 ASN 56.A OD1 no hydrogen 2.844 N/A MET 61.A N MET 57.A O no hydrogen 2.873 N/A HIS 62.A N VAL 58.A O no hydrogen 2.812 N/A GLU 63.A N GLU 59.A O no hydrogen 2.852 N/A ASP 64.A N GLN 60.A O no hydrogen 2.868 N/A ILE 65.A N MET 61.A O no hydrogen 2.829 N/A ILE 66.A N HIS 62.A O no hydrogen 2.852 N/A SER 67.A N GLU 63.A O no hydrogen 2.859 N/A SER 67.A OG.B GLU 63.A O no hydrogen 3.341 N/A SER 67.A OG.B ASP 64.A O no hydrogen 2.321 N/A SER 67.A OG.C GLN 71.A OE1 no hydrogen 2.798 N/A LEU 68.A N ASP 64.A O no hydrogen 2.826 N/A TRP 69.A N ILE 65.A O no hydrogen 2.863 N/A ASP 70.A N ILE 66.A O no hydrogen 2.819 N/A GLN 71.A N SER 67.A O no hydrogen 2.827 N/A GLN 71.A NE2 HIS 29.A NE2 no hydrogen 3.214 N/A SER 72.A N LEU 68.A O no hydrogen 2.755 N/A SER 72.A OG LEU 68.A O no hydrogen 2.724 N/A LEU 73.A N TRP 69.A O no hydrogen 2.787 N/A LYS 74.A NZ ASP 70.A O no hydrogen 3.030 N/A VAL 77.A N MET 288.A O no hydrogen 2.994 N/A LYS 78.A N ILE 85.A O no hydrogen 2.729 N/A LEU 79.A N LYS 286.A O no hydrogen 2.865 N/A THR 80.A N SER 83.A O no hydrogen 2.881 N/A THR 80.A OG1 GLU 283.A OE1 no hydrogen 3.160 N/A THR 80.A OG1 VAL 284.A O no hydrogen 3.218 N/A SER 83.A N THR 80.A O no hydrogen 2.802 N/A ILE 85.A N LYS 78.A O no hydrogen 2.823 N/A GLN 87.A N CYS 76.A O no hydrogen 3.182 N/A LYS 91.A NZ GLU 243.A OE1 no hydrogen 3.165 N/A LYS 91.A NZ GLU 243.A OE2 no hydrogen 3.089 N/A LYS 91.A NZ ALA 290.A O no hydrogen 2.947 N/A GLU 95.A N GLU 21.A OE1 no hydrogen 2.745 N/A ILE 99.A N ILE 135.A O no hydrogen 2.696 N/A HIS 100.A N ALA 12.A O no hydrogen 2.807 N/A HIS 100.A ND1 THR 132.A O no hydrogen 2.844 N/A TYR 101.A N THR 132.A OG1 no hydrogen 2.985 N/A TYR 101.A OH ASP 64.A OD2 no hydrogen 2.892 N/A CYS 102.A N PHE 10.A O no hydrogen 2.712 N/A CYS 102.A SG HIS 100.A O no hydrogen 3.990 N/A ALA 103.A N GLN 130.A O no hydrogen 2.997 N/A PHE 107.A N PRO 104.A O no hydrogen 3.094 N/A ALA 108.A N VAL 340.A O no hydrogen 2.803 N/A ILE 109.A N VAL 129.A O no hydrogen 2.902 N/A LEU 110.A N LYS 338.A O no hydrogen 2.758 N/A LYS 111.A N SER 127.A O no hydrogen 2.797 N/A CYS 112.A N LYS 336.A O no hydrogen 2.755 N/A ASN 113.A N ASN 125.A O no hydrogen 2.792 N/A ASN 113.A ND2 ASN 125.A O no hydrogen 3.306 N/A ASN 113.A ND2 SER 127.A OG no hydrogen 2.815 N/A LYS 116.A NZ GLU 152.A OE1 no hydrogen 3.090 N/A PHE 117.A N ASP 114.A O no hydrogen 3.336 N/A THR 120.A N ASN 118.A OD1 no hydrogen 3.330 N/A GLY 121.A N PHE 50.A O no hydrogen 2.753 N/A CYS 123.A N GLU 48.A O no hydrogen 2.706 N/A CYS 123.A SG ASP 114.A OD2 no hydrogen 3.348 N/A CYS 123.A SG ASN 125.A O no hydrogen 3.842 N/A THR 124.A N ASP 114.A OD2 no hydrogen 2.923 N/A THR 124.A OG1 ASP 114.A OD1 no hydrogen 3.339 N/A THR 124.A OG1 ASP 114.A OD2 no hydrogen 3.052 N/A ASN 125.A N ASP 114.A OD1 no hydrogen 3.146 N/A SER 127.A N LYS 111.A O no hydrogen 2.899 N/A SER 127.A OG GLU 40.A OE2 no hydrogen 2.549 N/A THR 128.A N VAL 41.A O no hydrogen 2.894 N/A VAL 129.A N ILE 109.A O no hydrogen 2.805 N/A THR 132.A N TYR 101.A O no hydrogen 2.918 N/A THR 132.A OG1 HIS 133.A O no hydrogen 3.088 N/A HIS 133.A N TYR 337.A OH no hydrogen 3.045 N/A HIS 133.A ND1 TYR 337.A OH no hydrogen 2.635 N/A HIS 133.A NE2 GLU 333.A OE1 no hydrogen 2.979 N/A ILE 135.A N ILE 99.A O no hydrogen 2.810 N/A VAL 138.A N ARG 136.A O no hydrogen 2.620 N/A SER 140.A OG LEU 143.A O no hydrogen 2.783 N/A THR 141.A N SER 237.A O no hydrogen 3.143 N/A THR 141.A OG1 GLU 232.A O no hydrogen 2.583 N/A THR 141.A OG1 THR 235.A O no hydrogen 3.176 N/A THR 141.A OG1 SER 237.A OG no hydrogen 3.027 N/A GLN 142.A N GLY 322.A O no hydrogen 2.959 N/A GLN 142.A NE2 ILE 233.A O no hydrogen 3.038 N/A GLN 142.A NE2 VAL 234.A O no hydrogen 2.939 N/A LEU 143.A N THR 141.A O no hydrogen 2.600 N/A LEU 144.A N GLY 305.A O no hydrogen 2.821 N/A ASN 146.A N ASN 302.A O no hydrogen 2.715 N/A GLY 147.A N THR 304.A OG1 no hydrogen 3.021 N/A SER 148.A N GLU 333.A OE2 no hydrogen 2.710 N/A SER 148.A OG HIS 133.A NE2 no hydrogen 3.117 N/A SER 148.A OG GLU 333.A OE1 no hydrogen 2.735 N/A ALA 150.A N LEU 172.A O no hydrogen 2.658 N/A VAL 155.A N GLN 171.A O no hydrogen 2.904 N/A ARG 157.A N ILE 169.A O no hydrogen 2.817 N/A ARG 157.A NE PHE 117.A O no hydrogen 2.779 N/A ARG 157.A NH1 GLN 171.A OE1 no hydrogen 2.725 N/A ARG 157.A NH2 PHE 117.A O no hydrogen 2.800 N/A ARG 157.A NH2 GLN 171.A OE1 no hydrogen 3.219 N/A ASN 160.A N SER 158.A OG no hydrogen 3.123 N/A THR 162.A N ASN 160.A OD1 no hydrogen 3.138 N/A THR 162.A OG1 ASN 160.A OD1 no hydrogen 2.831 N/A ASN 163.A N ASN 160.A O no hydrogen 3.075 N/A ASN 164.A ND2 ARG 310.A O no hydrogen 3.609 N/A ALA 165.A N ASN 163.A OD1 no hydrogen 2.962 N/A LYS 166.A N ASN 163.A O no hydrogen 3.082 N/A LYS 166.A NZ GLU 159.A OE1 no hydrogen 3.260 N/A ILE 168.A N LEU 308.A O no hydrogen 2.810 N/A ILE 169.A N ARG 157.A O no hydrogen 2.786 N/A VAL 170.A N LEU 306.A O no hydrogen 2.786 N/A GLN 171.A N VAL 155.A O no hydrogen 2.775 N/A GLN 171.A NE2 SER 148.A O no hydrogen 3.487 N/A GLN 171.A NE2 TYR 335.A OH no hydrogen 3.208 N/A LEU 172.A N THR 304.A O no hydrogen 3.048 N/A ASN 173.A ND2 GLU 152.A O no hydrogen 2.666 N/A VAL 176.A N ILE 303.A O no hydrogen 2.898 N/A ILE 178.A N SER 301.A O no hydrogen 2.817 N/A ASN 179.A N ASN 194.A O no hydrogen 2.897 N/A CYS 180.A N CYS 299.A O no hydrogen 2.779 N/A THR 181.A N HIS 192.A O no hydrogen 2.787 N/A ARG 182.A N ILE 297.A O no hydrogen 2.816 N/A ARG 182.A NE ARG 182.A O no hydrogen 2.932 N/A ARG 182.A NE PRO 183.A O no hydrogen 2.991 N/A ARG 182.A NH1 ILE 188.A O no hydrogen 2.751 N/A ARG 182.A NH1 ILE 293.A O no hydrogen 3.182 N/A ARG 182.A NH2 ILE 293.A O no hydrogen 2.606 N/A ARG 182.A NH2 GLY 295.A O no hydrogen 3.294 N/A ASN 184.A ND2 ASN 184.A O no hydrogen 2.475 N/A ARG 189.A N ASP 187.A OD1 no hydrogen 2.949 N/A ARG 189.A NE GLN 276.A OE1 no hydrogen 3.081 N/A ARG 189.A NH2 GLN 276.A OE1 no hydrogen 2.572 N/A GLN 190.A N ASP 187.A O no hydrogen 3.078 N/A ALA 191.A N CYS 272.A O no hydrogen 2.898 N/A HIS 192.A N THR 181.A O no hydrogen 2.872 N/A CYS 193.A N LEU 270.A O no hydrogen 2.843 N/A ASN 194.A N ASN 179.A O no hydrogen 2.768 N/A LEU 195.A N ILE 268.A O no hydrogen 2.868 N/A LYS 197.A NZ THR 264.A O no hydrogen 2.820 N/A THR 198.A OG1 SER 196.A OG no hydrogen 3.429 N/A GLN 199.A N SER 196.A OG no hydrogen 3.243 N/A TRP 200.A N SER 196.A O no hydrogen 3.148 N/A TRP 200.A NE1 LEU 252.A O no hydrogen 2.711 N/A GLU 201.A N LYS 197.A O no hydrogen 2.831 N/A ASN 202.A N THR 198.A O no hydrogen 2.847 N/A THR 203.A N GLN 199.A O no hydrogen 2.829 N/A THR 203.A OG1 GLN 199.A O no hydrogen 2.644 N/A LEU 204.A N TRP 200.A O no hydrogen 2.833 N/A GLU 205.A N GLU 201.A O no hydrogen 2.870 N/A GLN 206.A N ASN 202.A O no hydrogen 2.880 N/A ILE 207.A N THR 203.A O no hydrogen 2.848 N/A ALA 208.A N LEU 204.A O no hydrogen 2.808 N/A ILE 209.A N GLU 205.A O no hydrogen 2.870 N/A LYS 210.A N GLN 206.A O no hydrogen 2.890 N/A LYS 210.A NZ GLU 153.A OE1 no hydrogen 2.840 N/A LYS 210.A NZ GLU 213.A OE1 no hydrogen 3.431 N/A LYS 210.A NZ GLU 213.A OE2 no hydrogen 3.449 N/A LEU 211.A N ILE 207.A O no hydrogen 2.754 N/A LYS 212.A N ALA 208.A O no hydrogen 2.848 N/A LYS 212.A NZ ASN 217.A O no hydrogen 2.594 N/A LYS 212.A NZ LYS 219.A O no hydrogen 3.227 N/A GLU 213.A N ILE 209.A O no hydrogen 2.856 N/A GLN 214.A N LEU 211.A O no hydrogen 3.008 N/A PHE 215.A N LEU 211.A O no hydrogen 2.829 N/A GLY 216.A N LYS 212.A O no hydrogen 2.780 N/A LYS 219.A N GLY 216.A O no hydrogen 3.200 N/A LYS 219.A NZ GLU 317.A OE2 no hydrogen 3.504 N/A THR 220.A N GLY 315.A O no hydrogen 2.898 N/A ILE 222.A N GLU 317.A O no hydrogen 2.865 N/A PHE 223.A N TRP 255.A O no hydrogen 2.939 N/A ASN 224.A N PHE 319.A O no hydrogen 2.851 N/A GLY 228.A N SER 226.A OG no hydrogen 3.385 N/A GLU 232.A N GLU 232.A OE2 no hydrogen 2.826 N/A ILE 233.A N ASP 230.A O no hydrogen 3.054 N/A VAL 234.A N ASP 230.A O no hydrogen 3.079 N/A THR 235.A N PRO 231.A O no hydrogen 2.909 N/A THR 235.A OG1 PRO 231.A O no hydrogen 2.741 N/A HIS 236.A N CYS 247.A O no hydrogen 2.770 N/A HIS 236.A ND1 THR 141.A O no hydrogen 3.014 N/A SER 237.A N THR 141.A OG1 no hydrogen 3.141 N/A SER 237.A OG THR 141.A OG1 no hydrogen 3.027 N/A SER 237.A OG GLU 232.A O no hydrogen 2.869 N/A PHE 238.A N PHE 245.A O no hydrogen 2.912 N/A CYS 240.A N GLU 243.A O no hydrogen 2.893 N/A GLY 242.A N ASN 239.A OD1 no hydrogen 2.786 N/A GLU 243.A N CYS 240.A O no hydrogen 3.187 N/A PHE 245.A N PHE 238.A O no hydrogen 2.726 N/A TYR 246.A N ARG 273.A O no hydrogen 2.801 N/A TYR 246.A OH GLU 232.A OE1 no hydrogen 2.562 N/A CYS 247.A N HIS 236.A O no hydrogen 2.818 N/A ASN 248.A N PRO 271.A O no hydrogen 2.960 N/A SER 249.A OG GLN 142.A OE1 no hydrogen 2.574 N/A THR 250.A N ASN 248.A OD1 no hydrogen 2.995 N/A THR 250.A OG1 ASN 248.A OD1 no hydrogen 2.980 N/A GLN 251.A NE2 THR 269.A O no hydrogen 3.047 N/A LEU 252.A N SER 249.A O no hydrogen 2.961 N/A PHE 253.A N SER 249.A O no hydrogen 3.135 N/A PHE 253.A N THR 250.A O no hydrogen 3.224 N/A THR 254.A OG1 THR 250.A O no hydrogen 2.738 N/A TRP 255.A N PHE 223.A O no hydrogen 3.025 N/A THR 258.A N ASN 256.A OD1 no hydrogen 3.070 N/A THR 258.A OG1 ASN 256.A OD1 no hydrogen 2.637 N/A ARG 259.A N ASN 256.A O no hydrogen 2.917 N/A LYS 260.A N ASP 257.A O no hydrogen 2.848 N/A LYS 260.A NZ ASP 257.A OD1 no hydrogen 3.351 N/A LEU 261.A N THR 258.A O no hydrogen 2.896 N/A ASN 262.A N ARG 259.A O no hydrogen 3.209 N/A ILE 268.A N LEU 195.A O no hydrogen 2.724 N/A THR 269.A OG1 ASN 194.A OD1 no hydrogen 2.490 N/A LEU 270.A N CYS 193.A O no hydrogen 2.737 N/A CYS 272.A N ALA 191.A O no hydrogen 2.775 N/A CYS 272.A SG LEU 270.A O no hydrogen 3.550 N/A ARG 273.A N TYR 246.A O no hydrogen 2.854 N/A ARG 273.A NH1 ASP 187.A OD2 no hydrogen 2.932 N/A ARG 273.A NH1 GLN 190.A OE1 no hydrogen 3.212 N/A ILE 274.A N ARG 189.A O no hydrogen 2.905 N/A LYS 275.A N PHE 244.A O no hydrogen 3.075 N/A LYS 275.A NZ ILE 277.A O no hydrogen 3.408 N/A GLN 276.A NE2 TYR 289.A O no hydrogen 3.024 N/A ILE 278.A N ALA 287.A O no hydrogen 2.772 N/A ASN 279.A N GLU 232.A OE1 no hydrogen 2.868 N/A ASN 279.A ND2 GLU 232.A OE1 no hydrogen 3.384 N/A ASN 279.A ND2 GLU 232.A OE2 no hydrogen 2.739 N/A MET 280.A N GLY 285.A O no hydrogen 2.894 N/A TRP 281.A N GLN 282.A OE1 no hydrogen 3.177 N/A GLN 282.A N GLN 282.A OE1 no hydrogen 2.741 N/A GLN 282.A NE2 ASP 70.A OD1 no hydrogen 3.266 N/A LYS 286.A N LEU 79.A O no hydrogen 2.883 N/A LYS 286.A NZ ASN 279.A OD1 no hydrogen 2.796 N/A ALA 287.A N ILE 278.A O no hydrogen 2.768 N/A MET 288.A N VAL 77.A O no hydrogen 2.660 N/A TYR 289.A N GLN 276.A O no hydrogen 2.807 N/A TYR 289.A OH LEU 73.A O no hydrogen 3.005 N/A ILE 293.A N GLU 243.A OE2 no hydrogen 2.975 N/A ILE 297.A N ARG 182.A O no hydrogen 3.208 N/A CYS 299.A N CYS 180.A O no hydrogen 2.864 N/A SER 300.A OG ASN 179.A OD1 no hydrogen 2.732 N/A SER 301.A N ILE 178.A O no hydrogen 2.878 N/A ASN 302.A N ASN 146.A OD1 no hydrogen 3.078 N/A ILE 303.A N VAL 176.A O no hydrogen 2.784 N/A THR 304.A N LEU 144.A O no hydrogen 2.863 N/A THR 304.A OG1 LEU 144.A O no hydrogen 3.409 N/A GLY 305.A N LEU 144.A O no hydrogen 3.287 N/A LEU 306.A N VAL 170.A O no hydrogen 2.810 N/A LEU 307.A N GLN 142.A O no hydrogen 2.858 N/A LEU 308.A N ILE 168.A O no hydrogen 2.823 N/A THR 309.A N ARG 320.A O no hydrogen 2.807 N/A ARG 310.A NH1 GLU 317.A OE1 no hydrogen 3.388 N/A ARG 310.A NH2 PHE 161.A O no hydrogen 2.939 N/A ASP 311.A N ILE 318.A O no hydrogen 3.048 N/A GLU 317.A N THR 220.A O no hydrogen 2.793 N/A PHE 319.A N ILE 222.A O no hydrogen 2.758 N/A ARG 320.A N THR 309.A O no hydrogen 2.832 N/A ARG 320.A NE ASP 311.A OD1 no hydrogen 2.872 N/A ARG 320.A NE ASP 311.A OD2 no hydrogen 3.288 N/A ARG 320.A NH1 PRO 225.A O no hydrogen 2.939 N/A ARG 320.A NH2 ASP 311.A OD2 no hydrogen 2.976 N/A GLY 322.A N LEU 307.A O no hydrogen 2.683 N/A ARG 327.A N ASP 325.A OD1 no hydrogen 3.070 N/A ASP 328.A N ASP 325.A O no hydrogen 2.970 N/A ASN 329.A ND2 VAL 138.A O no hydrogen 3.527 N/A ASN 329.A ND2 SER 140.A O no hydrogen 3.084 N/A TRP 330.A N MET 326.A O no hydrogen 3.279 N/A TRP 330.A NE1 HIS 62.A ND1 no hydrogen 3.237 N/A ARG 331.A N ARG 327.A O no hydrogen 2.792 N/A ARG 331.A NE MET 52.A O no hydrogen 3.199 N/A ARG 331.A NH1 ASP 328.A OD1 no hydrogen 2.817 N/A SER 332.A N ASP 328.A O no hydrogen 2.749 N/A SER 332.A OG ASN 329.A O no hydrogen 2.529 N/A GLU 333.A N TRP 330.A O no hydrogen 3.039 N/A LEU 334.A N TRP 330.A O no hydrogen 2.796 N/A TYR 337.A N LEU 334.A O no hydrogen 3.074 N/A TYR 337.A OH HIS 133.A ND1 no hydrogen 2.635 N/A LYS 338.A N LEU 110.A O no hydrogen 2.857 N/A LYS 338.A NZ GLU 4.A OE1 no hydrogen 3.480 N/A LYS 338.A NZ GLU 48.A OE2 no hydrogen 2.897 N/A LYS 338.A NZ ASN 49.A O no hydrogen 2.642 N/A VAL 340.A N ALA 108.A O no hydrogen 2.876 N/A LYS 341.A N LYS 3.A O no hydrogen 2.950 N/A ILE 342.A N GLY 106.A O no hydrogen 2.898 N/A