Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4lss_G.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TRP 2.A NE1 GLU 48.A OE1 no hydrogen 3.105 N/A LEU 9.A N GLN 60.A OE1 no hydrogen 2.974 N/A PHE 10.A N CYS 102.A O no hydrogen 3.077 N/A CYS 11.A SG ALA 30.A O no hydrogen 3.185 N/A ALA 12.A N HIS 100.A O no hydrogen 2.940 N/A SER 13.A N VAL 32.A O no hydrogen 3.016 N/A ALA 15.A N SER 13.A OG no hydrogen 3.273 N/A LYS 16.A N ASN 24.A OD1 no hydrogen 3.214 N/A LYS 16.A NZ ASP 14.A O no hydrogen 3.380 N/A LYS 19.A N LYS 16.A O no hydrogen 3.439 N/A VAL 22.A N THR 93.A O no hydrogen 3.040 N/A HIS 23.A N GLU 21.A OE2 no hydrogen 2.671 N/A HIS 23.A ND1 GLU 21.A OE2 no hydrogen 2.739 N/A ASN 24.A N GLU 21.A OE1 no hydrogen 2.729 N/A ASN 24.A ND2 GLU 21.A OE1 no hydrogen 2.591 N/A VAL 25.A N GLU 21.A O no hydrogen 2.935 N/A TRP 26.A N VAL 22.A O no hydrogen 3.025 N/A ALA 27.A N HIS 23.A O no hydrogen 3.108 N/A THR 28.A N ASN 24.A O no hydrogen 2.939 N/A THR 28.A OG1 LYS 16.A O no hydrogen 3.529 N/A THR 28.A OG1 ASN 24.A O no hydrogen 2.933 N/A HIS 29.A N TRP 26.A O no hydrogen 3.072 N/A ALA 30.A N TRP 26.A O no hydrogen 2.780 N/A CYS 31.A N ALA 27.A O no hydrogen 3.064 N/A VAL 32.A N CYS 11.A O no hydrogen 3.070 N/A ASN 37.A N ASP 35.A OD1 no hydrogen 3.404 N/A ILE 41.A N THR 128.A O no hydrogen 2.952 N/A LEU 43.A N VAL 126.A O no hydrogen 3.148 N/A THR 47.A OG1 CYS 123.A O no hydrogen 2.803 N/A GLU 48.A N CYS 123.A O no hydrogen 3.149 N/A PHE 50.A N GLY 121.A O no hydrogen 2.966 N/A VAL 52.A N GLY 119.A O no hydrogen 3.017 N/A TRP 53.A N ASN 51.A OD1 no hydrogen 2.862 N/A LYS 54.A N ASN 51.A O no hydrogen 2.982 N/A LYS 54.A NZ GLU 159.A OE2 no hydrogen 2.397 N/A ASN 55.A N VAL 52.A O no hydrogen 3.055 N/A MET 57.A N ASN 55.A OD1 no hydrogen 2.931 N/A VAL 58.A N ASN 55.A O no hydrogen 2.935 N/A GLN 60.A N ASN 56.A O no hydrogen 3.140 N/A GLN 60.A NE2 THR 7.A O no hydrogen 3.268 N/A GLN 60.A NE2 ASN 56.A O no hydrogen 3.366 N/A MET 61.A N MET 57.A O no hydrogen 2.960 N/A HIS 62.A N VAL 58.A O no hydrogen 3.047 N/A THR 63.A N GLU 59.A O no hydrogen 3.102 N/A THR 63.A OG1 GLU 59.A O no hydrogen 3.186 N/A THR 63.A OG1 GLN 60.A O no hydrogen 2.865 N/A ASP 64.A N GLN 60.A O no hydrogen 3.095 N/A ILE 65.A N MET 61.A O no hydrogen 2.959 N/A ILE 66.A N HIS 62.A O no hydrogen 2.954 N/A SER 67.A N THR 63.A O no hydrogen 3.032 N/A SER 67.A OG GLN 71.A OE1 no hydrogen 3.488 N/A LEU 68.A N ASP 64.A O no hydrogen 2.733 N/A TRP 69.A N ILE 65.A O no hydrogen 3.231 N/A ASP 70.A N ILE 66.A O no hydrogen 2.972 N/A GLN 71.A N SER 67.A O no hydrogen 3.110 N/A GLN 71.A N LEU 68.A O no hydrogen 3.252 N/A SER 72.A N TRP 69.A O no hydrogen 3.240 N/A SER 72.A OG LEU 68.A O no hydrogen 2.819 N/A LEU 73.A N TRP 69.A O no hydrogen 3.147 N/A CYS 76.A N MET 278.A O no hydrogen 2.611 N/A VAL 77.A N MET 278.A O no hydrogen 3.454 N/A LYS 78.A N ILE 85.A O no hydrogen 2.835 N/A LEU 79.A N GLN 276.A O no hydrogen 2.779 N/A SER 83.A OG GLY 82.A O no hydrogen 2.551 N/A ILE 85.A N LYS 78.A O no hydrogen 3.281 N/A GLN 87.A N CYS 76.A O no hydrogen 3.078 N/A CYS 89.A SG GLN 87.A O no hydrogen 3.649 N/A LYS 91.A NZ GLU 240.A OE2 no hydrogen 3.089 N/A GLU 95.A N GLU 21.A OE2 no hydrogen 3.178 N/A ILE 99.A N ILE 135.A O no hydrogen 2.752 N/A HIS 100.A N ALA 12.A O no hydrogen 2.825 N/A HIS 100.A ND1 THR 132.A O no hydrogen 3.107 N/A TYR 101.A N THR 132.A OG1 no hydrogen 2.718 N/A TYR 101.A OH ASP 64.A OD2 no hydrogen 3.090 N/A CYS 102.A N PHE 10.A O no hydrogen 2.741 N/A ALA 103.A N GLN 130.A O no hydrogen 3.009 N/A PHE 107.A N PRO 104.A O no hydrogen 3.067 N/A ALA 108.A N VAL 332.A O no hydrogen 3.091 N/A ILE 109.A N VAL 129.A O no hydrogen 3.268 N/A LEU 110.A N LYS 330.A O no hydrogen 2.810 N/A LYS 111.A N SER 127.A O no hydrogen 2.867 N/A CYS 112.A N LYS 328.A O no hydrogen 2.821 N/A LYS 113.A N ASN 125.A O no hydrogen 2.805 N/A LYS 113.A NZ GLU 40.A OE2 no hydrogen 3.491 N/A ASN 118.A N ASN 118.A OD1 no hydrogen 2.577 N/A ASN 118.A ND2 THR 120.A O no hydrogen 2.952 N/A GLY 121.A N PHE 50.A O no hydrogen 2.947 N/A CYS 123.A N GLU 48.A O no hydrogen 2.886 N/A CYS 123.A SG ASN 125.A O no hydrogen 3.105 N/A LYS 124.A N ASP 114.A OD1 no hydrogen 3.232 N/A LYS 124.A N ASP 114.A OD2 no hydrogen 3.293 N/A ASN 125.A N ASP 114.A OD1 no hydrogen 2.806 N/A SER 127.A N LYS 111.A O no hydrogen 3.133 N/A SER 127.A OG GLU 40.A OE2 no hydrogen 2.928 N/A THR 128.A N ILE 41.A O no hydrogen 2.614 N/A THR 128.A OG1 ILE 109.A O no hydrogen 3.397 N/A VAL 129.A N ILE 109.A O no hydrogen 2.904 N/A CYS 131.A SG GLN 130.A O no hydrogen 3.141 N/A THR 132.A N TYR 101.A O no hydrogen 2.737 N/A THR 132.A OG1 TYR 101.A O no hydrogen 3.513 N/A THR 132.A OG1 HIS 133.A O no hydrogen 3.131 N/A HIS 133.A N TYR 329.A OH no hydrogen 3.162 N/A HIS 133.A ND1 TYR 329.A OH no hydrogen 2.774 N/A ILE 135.A N ILE 99.A O no hydrogen 2.636 N/A VAL 138.A N LYS 136.A O no hydrogen 2.828 N/A SER 140.A OG LEU 143.A O no hydrogen 2.486 N/A THR 141.A N SER 234.A O no hydrogen 2.977 N/A THR 141.A OG1 GLU 229.A O no hydrogen 2.571 N/A THR 141.A OG1 THR 232.A O no hydrogen 2.824 N/A GLN 142.A N GLY 314.A O no hydrogen 3.099 N/A GLN 142.A NE2 ILE 230.A O no hydrogen 2.838 N/A LEU 143.A N THR 141.A O no hydrogen 2.703 N/A LEU 144.A N GLY 295.A O no hydrogen 2.855 N/A ASN 146.A N ASN 292.A O no hydrogen 2.814 N/A GLY 147.A N THR 294.A OG1 no hydrogen 3.209 N/A SER 148.A N GLU 325.A OE1 no hydrogen 3.276 N/A SER 148.A OG GLU 325.A OE1 no hydrogen 2.326 N/A ALA 150.A N LEU 172.A O no hydrogen 2.735 N/A ARG 155.A N GLN 171.A O no hydrogen 2.943 N/A LYS 157.A N ILE 169.A O no hydrogen 2.795 N/A ASN 160.A N SER 158.A OG no hydrogen 3.152 N/A ASP 163.A N ASN 160.A O no hydrogen 2.833 N/A ALA 165.A N ASP 163.A OD1 no hydrogen 2.863 N/A LYS 166.A N ASP 163.A O no hydrogen 2.943 N/A LYS 166.A NZ GLU 159.A OE1 no hydrogen 3.241 N/A THR 167.A OG1 ASP 320.A OD2 no hydrogen 3.211 N/A ILE 168.A N LEU 298.A O no hydrogen 2.849 N/A ILE 169.A N LYS 157.A O no hydrogen 2.797 N/A VAL 170.A N ILE 296.A O no hydrogen 2.781 N/A GLN 171.A N ARG 155.A O no hydrogen 2.837 N/A GLN 171.A NE2 SER 148.A O no hydrogen 3.040 N/A LEU 172.A N THR 294.A O no hydrogen 2.840 N/A THR 173.A OG1 ALA 150.A O no hydrogen 3.000 N/A THR 173.A OG1 GLU 151.A O no hydrogen 3.545 N/A VAL 176.A N ILE 293.A O no hydrogen 3.161 N/A ILE 178.A N SER 291.A O no hydrogen 2.860 N/A ASN 179.A N VAL 193.A O no hydrogen 3.212 N/A CYS 180.A N CYS 289.A O no hydrogen 3.475 N/A ALA 181.A N TYR 191.A O no hydrogen 3.096 N/A ARG 182.A N ILE 287.A O no hydrogen 2.807 N/A ARG 182.A NE ARG 182.A O no hydrogen 3.446 N/A ARG 182.A NH1 ILE 187.A O no hydrogen 3.258 N/A ARG 182.A NH1 ILE 283.A O no hydrogen 3.431 N/A ARG 182.A NH2 ILE 283.A O no hydrogen 3.140 N/A ARG 182.A NH2 GLY 285.A O no hydrogen 2.451 N/A ARG 188.A N ASP 186.A OD1 no hydrogen 2.745 N/A ARG 188.A NE GLN 266.A OE1 no hydrogen 3.176 N/A ARG 188.A NH2 GLN 266.A OE1 no hydrogen 2.593 N/A GLN 189.A N ASP 186.A O no hydrogen 3.510 N/A ALA 190.A N CYS 262.A O no hydrogen 2.834 N/A TYR 191.A N ALA 181.A O no hydrogen 3.132 N/A CYS 192.A N LEU 260.A O no hydrogen 2.761 N/A VAL 193.A N ASN 179.A O no hydrogen 2.876 N/A VAL 194.A N ILE 258.A O no hydrogen 3.124 N/A ARG 196.A N ASP 256.A O no hydrogen 3.327 N/A GLN 198.A N ASN 195.A OD1 no hydrogen 3.188 N/A TRP 199.A N ASN 195.A O no hydrogen 2.909 N/A TRP 199.A NE1 LEU 249.A O no hydrogen 2.871 N/A ASN 200.A N ARG 196.A O no hydrogen 2.777 N/A ASP 201.A N THR 197.A O no hydrogen 2.929 N/A THR 202.A N GLN 198.A O no hydrogen 3.160 N/A THR 202.A OG1 GLN 198.A O no hydrogen 2.772 N/A LEU 203.A N TRP 199.A O no hydrogen 2.909 N/A GLY 204.A N ASN 200.A O no hydrogen 3.078 N/A GLN 205.A N ASP 201.A O no hydrogen 3.164 N/A VAL 206.A N THR 202.A O no hydrogen 3.001 N/A ALA 207.A N LEU 203.A O no hydrogen 2.997 N/A ILE 208.A N GLY 204.A O no hydrogen 3.122 N/A GLN 209.A N GLN 205.A O no hydrogen 3.339 N/A GLN 209.A NE2 GLU 153.A OE2 no hydrogen 3.112 N/A LEU 210.A N VAL 206.A O no hydrogen 2.834 N/A ARG 211.A N ALA 207.A O no hydrogen 2.974 N/A ARG 211.A NE THR 216.A O no hydrogen 2.946 N/A HIS 213.A N LEU 210.A O no hydrogen 3.204 N/A TRP 214.A N LEU 210.A O no hydrogen 3.107 N/A THR 216.A N TRP 214.A O no hydrogen 2.835 N/A ILE 218.A N TRP 254.A O no hydrogen 2.812 N/A ILE 219.A N GLU 309.A O no hydrogen 2.758 N/A PHE 220.A N SER 252.A O no hydrogen 2.941 N/A ASN 221.A N PHE 311.A O no hydrogen 2.883 N/A GLU 222.A N ASN 221.A OD1 no hydrogen 2.775 N/A ILE 230.A N ASP 227.A O no hydrogen 3.010 N/A THR 231.A N ASP 227.A O no hydrogen 3.055 N/A THR 232.A N LEU 228.A O no hydrogen 3.074 N/A THR 232.A OG1 LEU 228.A O no hydrogen 2.720 N/A HIS 233.A N CYS 244.A O no hydrogen 3.016 N/A HIS 233.A ND1 THR 141.A O no hydrogen 2.795 N/A SER 234.A N THR 141.A OG1 no hydrogen 2.839 N/A SER 234.A OG PHE 242.A O no hydrogen 3.112 N/A PHE 235.A N PHE 242.A O no hydrogen 3.153 N/A CYS 237.A N GLU 240.A O no hydrogen 2.750 N/A GLY 239.A N ASN 236.A OD1 no hydrogen 2.895 N/A GLU 240.A N CYS 237.A O no hydrogen 2.965 N/A PHE 242.A N PHE 235.A O no hydrogen 2.833 N/A TYR 243.A N ARG 263.A O no hydrogen 2.981 N/A TYR 243.A OH GLU 229.A OE2 no hydrogen 2.624 N/A CYS 244.A N HIS 233.A O no hydrogen 3.040 N/A ASN 245.A N PRO 261.A O no hydrogen 2.957 N/A THR 246.A OG1 GLN 142.A OE1 no hydrogen 2.610 N/A SER 247.A N ASN 245.A OD1 no hydrogen 3.001 N/A SER 247.A OG ASN 245.A OD1 no hydrogen 2.830 N/A LEU 249.A N THR 246.A O no hydrogen 2.758 N/A PHE 250.A N THR 246.A O no hydrogen 3.172 N/A SER 252.A N PHE 220.A O no hydrogen 3.196 N/A TRP 254.A N ILE 218.A O no hydrogen 2.829 N/A TRP 254.A NE1 SER 252.A OG no hydrogen 3.004 N/A ILE 258.A N VAL 194.A O no hydrogen 2.820 N/A LEU 260.A N CYS 192.A O no hydrogen 2.641 N/A CYS 262.A N ALA 190.A O no hydrogen 2.949 N/A CYS 262.A SG LEU 260.A O no hydrogen 3.596 N/A ARG 263.A N TYR 243.A O no hydrogen 2.995 N/A ARG 263.A NH2 ASP 186.A OD2 no hydrogen 2.969 N/A ILE 264.A N ARG 188.A O no hydrogen 2.805 N/A LYS 265.A N PHE 241.A O no hydrogen 3.215 N/A GLN 266.A NE2 TYR 279.A O no hydrogen 2.995 N/A ILE 268.A N ALA 277.A O no hydrogen 3.047 N/A ASN 269.A N GLU 229.A OE2 no hydrogen 3.002 N/A ASN 269.A ND2 GLU 229.A OE1 no hydrogen 2.848 N/A ASN 269.A ND2 GLU 229.A OE2 no hydrogen 3.406 N/A MET 270.A N GLY 275.A O no hydrogen 2.850 N/A GLN 272.A N GLN 272.A OE1 no hydrogen 2.660 N/A GLN 272.A NE2 ASP 70.A OD1 no hydrogen 3.221 N/A ARG 273.A NH1 ASP 70.A OD1 no hydrogen 3.219 N/A ARG 273.A NH1 ASP 70.A OD2 no hydrogen 3.237 N/A ARG 273.A NH2 ASP 70.A OD2 no hydrogen 2.924 N/A GLN 276.A N LEU 79.A O no hydrogen 2.998 N/A ALA 277.A N ILE 268.A O no hydrogen 3.001 N/A MET 278.A N VAL 77.A O no hydrogen 2.924 N/A TYR 279.A N GLN 266.A O no hydrogen 2.693 N/A ILE 283.A N GLU 240.A OE2 no hydrogen 3.005 N/A ILE 287.A N ARG 182.A O no hydrogen 3.466 N/A ARG 288.A NH1 ASN 179.A OD1 no hydrogen 2.551 N/A CYS 289.A N CYS 180.A O no hydrogen 2.986 N/A CYS 289.A SG CYS 289.A O no hydrogen 2.934 N/A SER 291.A N ILE 178.A O no hydrogen 2.811 N/A ASN 292.A N ASN 146.A OD1 no hydrogen 3.270 N/A ILE 293.A N VAL 176.A O no hydrogen 2.872 N/A THR 294.A N LEU 144.A O no hydrogen 3.014 N/A GLY 295.A N LEU 144.A O no hydrogen 3.398 N/A ILE 296.A N VAL 170.A O no hydrogen 3.058 N/A LEU 297.A N GLN 142.A O no hydrogen 2.987 N/A LEU 298.A N ILE 168.A O no hydrogen 2.879 N/A THR 299.A N ARG 312.A O no hydrogen 2.806 N/A ARG 300.A NH1 GLU 309.A OE1 no hydrogen 3.330 N/A ASP 301.A N THR 310.A O no hydrogen 3.038 N/A GLU 309.A N THR 217.A O no hydrogen 2.934 N/A PHE 311.A N ILE 219.A O no hydrogen 2.686 N/A ARG 312.A N THR 299.A O no hydrogen 2.975 N/A ARG 312.A NE ASP 301.A OD1 no hydrogen 3.019 N/A ARG 312.A NE ASP 301.A OD2 no hydrogen 3.085 N/A ARG 312.A NH1 GLU 222.A O no hydrogen 2.697 N/A ARG 312.A NH2 ASP 301.A OD2 no hydrogen 2.938 N/A GLY 314.A N LEU 297.A O no hydrogen 2.682 N/A ARG 319.A N ASP 317.A OD1 no hydrogen 2.996 N/A ARG 319.A NE ASP 317.A OD2 no hydrogen 3.493 N/A ARG 319.A NH1 GLU 59.A OE1 no hydrogen 3.477 N/A ASP 320.A N ASP 317.A O no hydrogen 3.028 N/A ASN 321.A ND2 VAL 138.A O no hydrogen 3.655 N/A ASN 321.A ND2 SER 140.A O no hydrogen 3.248 N/A TRP 322.A N MET 318.A O no hydrogen 3.198 N/A TRP 322.A NE1 HIS 62.A ND1 no hydrogen 3.163 N/A ARG 323.A N ARG 319.A O no hydrogen 2.826 N/A ARG 323.A NH1 ASP 320.A OD1 no hydrogen 2.752 N/A SER 324.A N ASP 320.A O no hydrogen 3.019 N/A SER 324.A OG ASN 321.A O no hydrogen 2.667 N/A GLU 325.A N TRP 322.A O no hydrogen 2.957 N/A LEU 326.A N TRP 322.A O no hydrogen 2.878 N/A TYR 329.A N LEU 326.A O no hydrogen 3.111 N/A TYR 329.A OH HIS 133.A ND1 no hydrogen 2.774 N/A LYS 330.A NZ ASN 4.A OD1 no hydrogen 2.661 N/A LYS 330.A NZ GLU 48.A OE1 no hydrogen 2.643 N/A LYS 330.A NZ GLU 49.A O no hydrogen 2.667 N/A VAL 332.A N ALA 108.A O no hydrogen 3.174 N/A LYS 333.A N LYS 3.A O no hydrogen 3.323 N/A ILE 334.A N GLY 106.A O no hydrogen 2.957 N/A