Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4lxx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 4.A N HIS 2.A ND1 no hydrogen 2.935 N/A LYS 5.A N GLN 31.A O no hydrogen 2.777 N/A LYS 5.A NZ.B HIS 2.A O no hydrogen 2.762 N/A ILE 6.A N GLN 31.A O no hydrogen 3.256 N/A CYS 7.A N ILE 74.A O no hydrogen 2.775 N/A CYS 7.A SG VAL 33.A O no hydrogen 3.874 N/A ILE 8.A N VAL 33.A O no hydrogen 2.998 N/A ALA 9.A N PHE 76.A O no hydrogen 3.003 N/A GLY 10.A N ILE 35.A O no hydrogen 3.015 N/A LYS 11.A N LEU 78.A O no hydrogen 3.019 N/A ASN 12.A ND2 TYR 156.A OH no hydrogen 2.867 N/A ASN 13.A N GLN 47.A OE1 no hydrogen 2.789 N/A VAL 16.A N ASN 12.A O no hydrogen 3.015 N/A ASN 17.A N ASN 13.A O no hydrogen 2.871 N/A ASN 17.A ND2 GLU 164.A OE2 no hydrogen 2.950 N/A SER 18.A N ILE 14.A O no hydrogen 3.023 N/A SER 18.A OG ILE 14.A O no hydrogen 2.732 N/A LEU 19.A N ALA 15.A O no hydrogen 2.912 N/A GLN 20.A N VAL 16.A O no hydrogen 2.856 N/A PHE 21.A N ASN 17.A O no hydrogen 2.973 N/A ILE 22.A N SER 18.A O no hydrogen 3.008 N/A LEU 23.A N LEU 19.A O no hydrogen 2.875 N/A LYS 24.A N GLN 20.A O no hydrogen 2.895 N/A ASN 25.A N PHE 21.A O no hydrogen 2.971 N/A ASN 25.A N ILE 22.A O no hydrogen 3.329 N/A ASN 25.A ND2 PHE 21.A O no hydrogen 3.043 N/A TYR 26.A N ILE 22.A O no hydrogen 2.787 N/A PHE 27.A N ILE 22.A O no hydrogen 2.944 N/A GLU 28.A N GLN 31.A OE1 no hydrogen 2.934 N/A GLN 31.A N GLU 28.A O no hydrogen 2.929 N/A ILE 32.A N ALA 29.A O no hydrogen 3.089 N/A VAL 33.A N ILE 6.A O no hydrogen 2.949 N/A VAL 34.A N LYS 60.A O no hydrogen 3.030 N/A ILE 35.A N ILE 8.A O no hydrogen 2.976 N/A ASN 37.A ND2 GLU 79.A O no hydrogen 2.913 N/A LYS 38.A N ASP 81.A OD1 no hydrogen 2.971 N/A ASP 40.A N ASN 37.A O no hydrogen 3.081 N/A GLY 42.A N ASP 40.A OD2 no hydrogen 2.923 N/A SER 45.A N GLN 47.A O no hydrogen 2.912 N/A GLN 47.A NE2 TRP 46.A O no hydrogen 3.109 N/A LYS 48.A N ASN 13.A OD1 no hydrogen 2.789 N/A LYS 48.A NZ ASN 17.A OD1 no hydrogen 2.771 N/A SER 49.A N ASP 44.A OD1 no hydrogen 2.904 N/A SER 49.A OG ASP 40.A OD1 no hydrogen 3.461 N/A SER 49.A OG ASP 40.A OD2 no hydrogen 2.615 N/A LEU 51.A N ASP 40.A OD1 no hydrogen 2.873 N/A LYS 52.A N SER 49.A OG no hydrogen 2.923 N/A LYS 52.A NZ ASP 56.A OD2 no hydrogen 2.917 N/A PHE 53.A N SER 49.A O no hydrogen 3.046 N/A ALA 54.A N LEU 50.A O no hydrogen 2.936 N/A LEU 55.A N LEU 51.A O no hydrogen 3.017 N/A ASP 56.A N LYS 52.A O no hydrogen 2.834 N/A ASN 57.A N PHE 53.A O no hydrogen 3.032 N/A ASN 57.A N ALA 54.A O no hydrogen 3.053 N/A ASN 57.A ND2 PHE 53.A O no hydrogen 2.924 N/A ASN 58.A N LEU 55.A O no hydrogen 3.293 N/A ILE 59.A N ALA 54.A O no hydrogen 2.904 N/A VAL 62.A N VAL 34.A O no hydrogen 2.924 N/A THR 63.A N GLU 66.A OE1 no hydrogen 3.046 N/A GLU 66.A N THR 63.A O no hydrogen 3.044 N/A GLU 66.A N THR 63.A OG1 no hydrogen 3.395 N/A ILE 67.A N LEU 64.A O no hydrogen 2.982 N/A TYR 68.A N LEU 64.A O no hydrogen 3.212 N/A ILE 70.A N ILE 67.A O no hydrogen 3.074 N/A ILE 73.A N ILE 70.A O no hydrogen 3.364 N/A ILE 74.A N LYS 5.A O no hydrogen 2.987 N/A PHE 75.A N ARG 93.A O no hydrogen 2.853 N/A PHE 76.A N CYS 7.A O no hydrogen 2.899 N/A SER 77.A N PHE 95.A O no hydrogen 2.808 N/A LEU 78.A N ALA 9.A O no hydrogen 2.834 N/A ASP 81.A N ASN 37.A OD1 no hydrogen 3.229 N/A ILE 86.A N ASN 131.A OD1 no hydrogen 2.832 N/A GLU 87.A N GLU 87.A OE1 no hydrogen 2.794 N/A ASN 88.A N LYS 85.A O no hydrogen 2.992 N/A PHE 89.A N ILE 86.A O no hydrogen 3.051 N/A LYS 90.A N TYR 68.A O no hydrogen 2.935 N/A LYS 90.A NZ ASN 69.A O no hydrogen 2.908 N/A SER 91.A OG ILE 73.A O no hydrogen 2.643 N/A ARG 93.A N SER 91.A OG no hydrogen 3.063 N/A ARG 93.A NH1 GLN 72.A O no hydrogen 2.879 N/A ARG 93.A NH2 ILE 174.A O no hydrogen 3.239 N/A ARG 93.A NH2 ILE 175.A O no hydrogen 2.809 N/A PHE 95.A N PHE 75.A O no hydrogen 2.861 N/A ASN 96.A N HIS 127.A O no hydrogen 2.937 N/A ASN 96.A ND2 SER 77.A O no hydrogen 3.176 N/A ILE 97.A N SER 77.A O no hydrogen 3.330 N/A HIS 98.A N THR 125.A O no hydrogen 2.800 N/A HIS 98.A NE2 TYR 105.A O no hydrogen 2.844 N/A SER 100.A OG LYS 104.A O no hydrogen 2.684 N/A SER 100.A OG TYR 105.A O no hydrogen 3.299 N/A LEU 102.A N THR 125.A OG1 no hydrogen 3.219 N/A LYS 104.A N ALA 101.A O no hydrogen 3.134 N/A LYS 104.A NZ GLU 119.A OE1 no hydrogen 3.460 N/A LYS 104.A NZ GLU 119.A OE2 no hydrogen 2.972 N/A TYR 105.A N SER 190.A OG no hydrogen 2.907 N/A TYR 105.A OH GLU 119.A OE2 no hydrogen 2.697 N/A LYS 106.A N SER 190.A O no hydrogen 2.856 N/A LYS 106.A NZ PRO 103.A O no hydrogen 2.891 N/A LYS 106.A NZ GLN 184.A OE1 no hydrogen 2.879 N/A LYS 106.A NZ SER 189.A OG no hydrogen 2.843 N/A GLY 107.A N ASP 134.A OD2 no hydrogen 2.857 N/A VAL 108.A N PHE 192.A O no hydrogen 2.997 N/A THR 110.A OG1 PHE 99.A O no hydrogen 2.663 N/A ILE 112.A N PHE 109.A O no hydrogen 2.937 N/A THR 113.A N PHE 109.A O no hydrogen 2.972 N/A THR 113.A OG1 PHE 109.A O no hydrogen 3.442 N/A ILE 115.A N ILE 112.A O no hydrogen 3.054 N/A LEU 116.A N ILE 112.A O no hydrogen 3.000 N/A ASN 117.A N THR 113.A O no hydrogen 3.044 N/A ASN 117.A ND2 THR 113.A O no hydrogen 2.860 N/A ASN 118.A N ILE 115.A O no hydrogen 2.923 N/A GLU 119.A N PRO 114.A O no hydrogen 2.943 N/A SER 122.A N PHE 144.A O no hydrogen 2.916 N/A SER 122.A OG TYR 159.A OH no hydrogen 2.681 N/A VAL 124.A N HIS 142.A O no hydrogen 2.933 N/A THR 125.A N HIS 98.A O no hydrogen 2.902 N/A THR 125.A OG1 SER 100.A O no hydrogen 2.678 N/A LEU 126.A N ASP 140.A O no hydrogen 2.851 N/A HIS 127.A N ASN 96.A O no hydrogen 2.946 N/A HIS 127.A ND1 ARG 128.A O no hydrogen 2.821 N/A HIS 127.A NE2 ASN 96.A OD1 no hydrogen 2.914 N/A ARG 128.A N ASN 137.A O no hydrogen 2.904 N/A ARG 128.A NH2 ASP 92.A O no hydrogen 2.993 N/A ILE 129.A N LEU 94.A O no hydrogen 2.875 N/A ASN 131.A ND2 GLU 87.A OE1 no hydrogen 2.992 N/A ASN 131.A ND2 GLU 87.A OE2 no hydrogen 3.332 N/A GLY 132.A N ASP 130.A OD2 no hydrogen 3.061 N/A THR 135.A OG1 ASP 130.A OD2 no hydrogen 2.565 N/A ASN 137.A ND2 ASP 181.A OD2 no hydrogen 2.994 N/A ILE 138.A N LEU 182.A O no hydrogen 2.886 N/A ILE 139.A N LEU 126.A O no hydrogen 2.808 N/A ASP 140.A N LEU 126.A O no hydrogen 3.238 N/A GLN 141.A N ASP 140.A OD2 no hydrogen 2.975 N/A GLN 141.A NE2 LEU 102.A O no hydrogen 2.915 N/A GLN 141.A NE2 THR 125.A OG1 no hydrogen 2.967 N/A HIS 142.A N VAL 124.A O no hydrogen 2.940 N/A CYS 143.A SG GLU 121.A OE1 no hydrogen 3.606 N/A CYS 143.A SG GLN 141.A OE1 no hydrogen 3.493 N/A PHE 144.A N SER 122.A O no hydrogen 2.971 N/A ILE 146.A N LEU 120.A O no hydrogen 2.877 N/A ASP 147.A N ASP 150.A OD2 no hydrogen 3.009 N/A ASP 150.A N ASP 147.A O no hydrogen 2.973 N/A THR 151.A N ASP 154.A OD2 no hydrogen 2.967 N/A ALA 152.A N ARG 217.A O no hydrogen 3.083 N/A ARG 153.A N ILE 220.A O no hydrogen 3.161 N/A ARG 153.A NE GLU 223.A OE1 no hydrogen 3.106 N/A ARG 153.A NE GLU 223.A OE2 no hydrogen 2.970 N/A ARG 153.A NH1 GLU 223.A OE2 no hydrogen 3.348 N/A ASP 154.A N THR 151.A OG1 no hydrogen 3.100 N/A LEU 155.A N THR 151.A O no hydrogen 2.932 N/A TYR 156.A N ALA 152.A O no hydrogen 2.860 N/A PHE 157.A N ARG 153.A O no hydrogen 3.011 N/A ASN 158.A N ASP 154.A O no hydrogen 3.044 N/A TYR 159.A N LEU 155.A O no hydrogen 2.895 N/A TYR 159.A OH THR 110.A O no hydrogen 2.692 N/A TYR 159.A OH SER 122.A OG no hydrogen 2.681 N/A LEU 160.A N TYR 156.A O no hydrogen 2.939 N/A LYS 161.A N PHE 157.A O no hydrogen 3.124 N/A TYR 162.A N ASN 158.A O no hydrogen 2.876 N/A GLY 163.A N TYR 159.A O no hydrogen 2.725 N/A GLU 164.A N LEU 160.A O no hydrogen 3.065 N/A SER 165.A N LYS 161.A O no hydrogen 3.124 N/A SER 165.A OG.A LYS 161.A O no hydrogen 3.235 N/A ILE 166.A N TYR 162.A O no hydrogen 2.939 N/A PHE 167.A N GLY 163.A O no hydrogen 3.092 N/A LYS 168.A N GLU 164.A O no hydrogen 3.088 N/A LYS 168.A NZ GLU 164.A OE1 no hydrogen 2.782 N/A LYS 169.A N SER 165.A O no hydrogen 2.952 N/A LYS 169.A NZ ASP 140.A OD1 no hydrogen 2.855 N/A ASN 170.A N ILE 166.A O no hydrogen 3.210 N/A ASN 170.A N PHE 167.A O no hydrogen 3.208 N/A ASN 170.A ND2 ASP 140.A OD1 no hydrogen 2.850 N/A ASN 170.A ND2 ILE 166.A O no hydrogen 2.958 N/A GLN 172.A NE2 TYR 26.A OH no hydrogen 2.868 N/A THR 173.A OG1 ASN 170.A O no hydrogen 2.856 N/A ILE 174.A N ASN 170.A O no hydrogen 3.122 N/A ILE 175.A N ILE 171.A O no hydrogen 2.864 N/A ASN 176.A N GLN 172.A O no hydrogen 2.837 N/A ASN 177.A N ILE 174.A O no hydrogen 3.117 N/A SER 178.A N THR 173.A O no hydrogen 2.876 N/A SER 178.A OG THR 173.A O no hydrogen 3.465 N/A LEU 182.A N ILE 138.A O no hydrogen 3.014 N/A GLN 184.A NE2 ASP 134.A O no hydrogen 2.888 N/A GLN 184.A NE2 GLY 136.A O no hydrogen 2.949 N/A THR 185.A OG1.A ILE 187.A O no hydrogen 2.789 N/A THR 185.A OG1.B ASN 186.A OD1 no hydrogen 3.509 N/A ILE 187.A N THR 185.A OG1.B no hydrogen 3.324 N/A SER 189.A N ASN 186.A O no hydrogen 3.484 N/A SER 190.A N PRO 103.A O no hydrogen 3.342 N/A PHE 192.A N LYS 106.A O no hydrogen 3.055 N/A SER 193.A N ASP 196.A OD2 no hydrogen 2.971 N/A ASP 196.A N SER 193.A O no hydrogen 2.930 N/A ILE 197.A N ARG 194.A O no hydrogen 3.255 N/A VAL 200.A N ASN 198.A OD1 no hydrogen 3.066 N/A HIS 201.A NE2 GLN 215.A OE1 no hydrogen 2.976 N/A ASN 204.A N GLN 215.A OE1 no hydrogen 2.913 N/A LYS 206.A N ASN 204.A OD1 no hydrogen 3.038 N/A LYS 207.A NZ GLU 211.A OE2 no hydrogen 3.326 N/A THR 208.A N GLU 211.A OE1 no hydrogen 2.914 N/A THR 208.A OG1 GLU 211.A OE1 no hydrogen 3.135 N/A SER 209.A N ASP 262.A OD1 no hydrogen 2.837 N/A SER 209.A OG ASP 262.A OD1 no hydrogen 3.523 N/A SER 209.A OG PHE 264.A O no hydrogen 2.631 N/A GLU 211.A N THR 208.A OG1 no hydrogen 3.037 N/A ILE 212.A N THR 208.A O no hydrogen 2.888 N/A HIS 213.A N SER 209.A O no hydrogen 2.857 N/A HIS 213.A ND1 SER 237.A OG no hydrogen 2.739 N/A HIS 213.A NE2 ILE 148.A O no hydrogen 2.683 N/A ASN 214.A N PHE 210.A O no hydrogen 2.864 N/A ASN 214.A ND2 ASN 118.A OD1 no hydrogen 2.836 N/A GLN 215.A N GLU 211.A O no hydrogen 2.958 N/A GLN 215.A NE2 ASN 204.A O no hydrogen 3.005 N/A GLN 215.A NE2 GLU 211.A O no hydrogen 3.252 N/A ILE 216.A N ILE 212.A O no hydrogen 3.008 N/A ARG 217.A N HIS 213.A O no hydrogen 2.922 N/A ARG 217.A NE ASN 214.A OD1 no hydrogen 2.820 N/A ARG 217.A NH1 ASP 147.A O no hydrogen 3.037 N/A ARG 217.A NH1 ASP 150.A O no hydrogen 2.834 N/A ARG 217.A NH2 ASN 214.A OD1 no hydrogen 2.914 N/A ALA 218.A N ASN 214.A O no hydrogen 2.930 N/A PHE 219.A N ILE 216.A O no hydrogen 3.142 N/A ILE 220.A N ARG 217.A O no hydrogen 3.147 N/A PHE 221.A N GLN 225.A O no hydrogen 3.160 N/A GLU 223.A N GLU 223.A OE1 no hydrogen 2.693 N/A TYR 224.A N PHE 221.A O no hydrogen 2.799 N/A GLN 225.A N PHE 221.A O no hydrogen 2.916 N/A GLN 225.A NE2 PHE 219.A O no hydrogen 3.063 N/A ILE 229.A N SER 232.A O no hydrogen 2.869 N/A ASN 230.A ND2 GLU 251.A OE1 no hydrogen 2.991 N/A SER 232.A N ILE 229.A O no hydrogen 2.884 N/A ILE 234.A N PRO 227.A O no hydrogen 2.920 N/A ILE 235.A N GLN 269.A O no hydrogen 2.946 N/A LYS 236.A NZ ASN 149.A O no hydrogen 2.804 N/A SER 237.A OG HIS 213.A ND1 no hydrogen 2.739 N/A ILE 238.A N ILE 267.A O no hydrogen 2.885 N/A LEU 239.A N ASN 149.A OD1 no hydrogen 2.986 N/A ALA 240.A N LYS 265.A O no hydrogen 2.904 N/A ILE 244.A N GLY 263.A O no hydrogen 2.855 N/A ASN 247.A N GLY 260.A O no hydrogen 3.015 N/A VAL 248.A N SER 259.A OG no hydrogen 2.924 N/A GLU 250.A N ILE 257.A O no hydrogen 2.912 N/A PHE 252.A N TYR 255.A O no hydrogen 2.831 N/A PHE 256.A N ALA 268.A O no hydrogen 2.894 N/A ILE 257.A N GLU 250.A O no hydrogen 2.911 N/A ILE 258.A N ILE 266.A O no hydrogen 2.957 N/A SER 259.A N VAL 248.A O no hydrogen 2.906 N/A SER 259.A OG GLY 245.A O no hydrogen 2.695 N/A GLY 260.A N SER 209.A OG no hydrogen 2.916 N/A ILE 261.A N LYS 207.A O no hydrogen 2.853 N/A GLY 263.A N GLY 260.A O no hydrogen 2.952 N/A LYS 265.A N GLU 242.A O no hydrogen 2.911 N/A ILE 266.A N ILE 258.A O no hydrogen 2.800 N/A ILE 267.A N ILE 238.A O no hydrogen 2.966 N/A ALA 268.A N PHE 256.A O no hydrogen 2.958 N/A GLN 269.A N LYS 236.A O no hydrogen 2.810 N/A LYS 270.A N ASN 254.A O no hydrogen 2.938 N/A LYS 270.A NZ GLU 251.A OE2 no hydrogen 2.771 N/A LYS 270.A NZ PHE 252.A O no hydrogen 2.781 N/A LYS 270.A NZ GLU 253.A O no hydrogen 3.325 N/A LEU 271.A N LYS 233.A O no hydrogen 2.822 N/A