Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4m40_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 9.A OG ARG 337.A O no hydrogen 2.418 N/A SER 12.A OG SER 10.A O no hydrogen 2.857 N/A HIS 14.A N VAL 26.A O no hydrogen 3.288 N/A VAL 16.A N VAL 24.A O no hydrogen 3.018 N/A THR 18.A N GLY 22.A O no hydrogen 2.837 N/A THR 18.A OG1 GLY 22.A O no hydrogen 2.588 N/A GLN 21.A N THR 18.A OG1 no hydrogen 3.017 N/A VAL 24.A N VAL 16.A O no hydrogen 2.907 N/A VAL 26.A N HIS 14.A O no hydrogen 2.671 N/A THR 27.A N THR 334.A O no hydrogen 2.952 N/A ILE 30.A N LEU 330.A O no hydrogen 2.764 N/A LEU 32.A N LEU 328.A O no hydrogen 2.967 N/A THR 35.A OG1 THR 310.A OG1 no hydrogen 2.717 N/A SER 39.A N TYR 299.A O no hydrogen 2.756 N/A SER 39.A OG HIS 40.A O no hydrogen 3.514 N/A HIS 40.A ND1 PHE 41.A O no hydrogen 3.239 N/A ASN 43.A N GLY 290.A O no hydrogen 2.942 N/A ASN 43.A ND2 GLY 290.A O no hydrogen 3.376 N/A LEU 44.A N THR 49.A OG1 no hydrogen 2.810 N/A LYS 45.A N ALA 292.A O no hydrogen 3.023 N/A THR 47.A N LEU 44.A O no hydrogen 3.044 N/A THR 49.A OG1 THR 47.A O no hydrogen 3.027 N/A ARG 50.A N ALA 81.A O no hydrogen 3.033 N/A ARG 50.A NH1 TYR 114.A O no hydrogen 3.012 N/A ARG 50.A NH2 PRO 77.A O no hydrogen 3.040 N/A ARG 50.A NH2 GLU 115.A O no hydrogen 2.906 N/A LEU 53.A N ASP 62.A OD1 no hydrogen 2.957 N/A CYS 54.A SG THR 56.A OG1 no hydrogen 3.542 N/A CYS 54.A SG VAL 75.A O no hydrogen 3.245 N/A CYS 57.A N CYS 54.A O no hydrogen 3.085 N/A CYS 60.A SG LEU 58.A O no hydrogen 3.413 N/A THR 61.A N ASP 64.A OD2 no hydrogen 3.268 N/A THR 61.A OG1 VAL 90.A O no hydrogen 2.707 N/A ASP 64.A N THR 61.A OG1 no hydrogen 3.343 N/A VAL 65.A N THR 61.A O no hydrogen 2.970 N/A ALA 66.A N ASP 62.A O no hydrogen 2.923 N/A LEU 67.A N LEU 63.A O no hydrogen 2.911 N/A GLY 68.A N VAL 65.A O no hydrogen 3.123 N/A ARG 69.A N ASP 64.A O no hydrogen 3.000 N/A CYS 72.A N ARG 69.A O no hydrogen 3.025 N/A THR 76.A OG1 ILE 117.A O no hydrogen 2.968 N/A ALA 79.A N GLU 115.A O no hydrogen 3.058 N/A SER 82.A N LYS 280.A O no hydrogen 2.854 N/A SER 82.A OG ARG 112.A O no hydrogen 3.244 N/A SER 82.A OG SER 279.A OG no hydrogen 3.066 N/A ILE 83.A N ARG 50.A O no hydrogen 3.246 N/A LEU 84.A N ILE 282.A O no hydrogen 2.839 N/A VAL 90.A N GLU 86.A OE1 no hydrogen 3.159 N/A THR 91.A N GLU 235.A OE1 no hydrogen 3.194 N/A THR 91.A OG1 HIS 99.A NE2 no hydrogen 3.005 N/A THR 91.A OG1 GLU 235.A O no hydrogen 2.787 N/A THR 91.A OG1 GLU 235.A OE1 no hydrogen 3.507 N/A SER 92.A N ASP 64.A OD1 no hydrogen 3.273 N/A SER 92.A N ASP 64.A OD2 no hydrogen 3.175 N/A SER 92.A OG ASN 59.A O no hydrogen 3.534 N/A SER 92.A OG ASP 64.A OD2 no hydrogen 2.553 N/A MET 98.A N ILE 245.A O no hydrogen 3.156 N/A HIS 99.A NE2 THR 91.A OG1 no hydrogen 3.005 N/A ARG 101.A N MET 98.A O no hydrogen 3.308 N/A ARG 101.A NH1 GLN 226.A OE1 no hydrogen 3.109 N/A ARG 101.A NH2 GLN 226.A OE1 no hydrogen 3.025 N/A THR 102.A N HIS 99.A O no hydrogen 3.315 N/A THR 102.A OG1 VAL 247.A O no hydrogen 2.551 N/A LYS 103.A NZ ASP 248.A OD1 no hydrogen 2.791 N/A LYS 103.A NZ ASP 248.A OD2 no hydrogen 3.287 N/A LYS 103.A NZ TYR 249.A O no hydrogen 3.223 N/A ILE 104.A N THR 102.A OG1 no hydrogen 3.278 N/A ARG 105.A NE ASP 100.A OD1 no hydrogen 3.307 N/A ARG 105.A NH1 PRO 89.A O no hydrogen 2.840 N/A ARG 105.A NH1 GLU 235.A OE1 no hydrogen 2.970 N/A ARG 105.A NH2 GLU 235.A OE1 no hydrogen 3.478 N/A ARG 105.A NH2 GLU 235.A OE2 no hydrogen 2.791 N/A GLN 106.A N LYS 103.A O no hydrogen 3.083 N/A GLN 106.A NE2 VAL 87.A O no hydrogen 2.922 N/A LEU 107.A N ILE 104.A O no hydrogen 2.925 N/A ASN 109.A ND2 GLU 86.A O no hydrogen 2.917 N/A ASN 109.A ND2 GLN 106.A OE1 no hydrogen 3.071 N/A LEU 110.A N GLN 106.A O no hydrogen 2.970 N/A LEU 111.A N LEU 107.A O no hydrogen 3.111 N/A ARG 112.A N PRO 108.A O no hydrogen 3.138 N/A ARG 112.A NE ASN 109.A OD1 no hydrogen 3.244 N/A ARG 112.A NH1 GLY 51.A O no hydrogen 3.143 N/A ARG 112.A NH2 ASP 62.A OD2 no hydrogen 2.819 N/A GLY 113.A N LEU 110.A O no hydrogen 3.349 N/A TYR 114.A N LEU 111.A O no hydrogen 3.082 N/A TYR 114.A OH ASP 185.A OD2 no hydrogen 2.761 N/A GLU 115.A N SER 276.A O no hydrogen 2.962 N/A LYS 116.A N SER 276.A O no hydrogen 2.893 N/A ARG 118.A N CYS 274.A O no hydrogen 2.906 N/A ARG 118.A NE GLU 184.A OE2 no hydrogen 3.033 N/A ARG 118.A NH2 GLU 184.A OE1 no hydrogen 3.029 N/A SER 120.A N VAL 272.A O no hydrogen 2.895 N/A SER 120.A OG GLN 122.A O no hydrogen 3.054 N/A SER 120.A OG VAL 272.A O no hydrogen 3.294 N/A VAL 124.A N GLN 270.A O no hydrogen 2.751 N/A LYS 129.A N ASN 126.A OD1 no hydrogen 3.410 N/A ALA 130.A N ALA 127.A O no hydrogen 3.240 N/A TYR 135.A N GLU 128.A O no hydrogen 3.094 N/A TYR 135.A OH PRO 131.A O no hydrogen 2.461 N/A ARG 136.A N VAL 160.A O no hydrogen 2.847 N/A GLY 138.A N TRP 158.A O no hydrogen 2.635 N/A SER 140.A N GLY 151.A O no hydrogen 2.959 N/A SER 142.A N SER 140.A OG no hydrogen 3.187 N/A SER 142.A OG CYS 94.A O no hydrogen 3.208 N/A CYS 143.A N SER 140.A O no hydrogen 3.158 N/A ALA 146.A N ASN 145.A OD1 no hydrogen 2.685 N/A SER 148.A OG SER 150.A O no hydrogen 2.845 N/A SER 150.A N SER 148.A OG no hydrogen 3.203 N/A GLY 151.A N SER 140.A O no hydrogen 2.859 N/A ALA 154.A N GLY 68.A O no hydrogen 2.705 N/A THR 155.A OG1 LEU 67.A O no hydrogen 2.566 N/A MET 156.A N PHE 153.A O no hydrogen 3.291 N/A ALA 157.A N LEU 268.A O no hydrogen 2.826 N/A TRP 158.A NE1 TYR 204.A OH no hydrogen 2.772 N/A ALA 159.A N ILE 266.A O no hydrogen 3.197 N/A VAL 160.A N ARG 136.A O no hydrogen 3.018 N/A LYS 162.A N PRO 134.A O no hydrogen 2.961 N/A LYS 166.A NZ ASN 202.A O no hydrogen 3.400 N/A THR 167.A OG1 ALA 168.A O no hydrogen 3.501 N/A THR 169.A OG1 ASN 170.A O no hydrogen 3.106 N/A LEU 172.A N TYR 262.A O no hydrogen 2.884 N/A VAL 174.A N ILE 260.A O no hydrogen 2.902 N/A VAL 176.A N GLY 258.A O no hydrogen 2.411 N/A HIS 178.A NE2 THR 181.A O no hydrogen 3.095 N/A ILE 179.A N GLN 186.A OE1 no hydrogen 2.590 N/A CYS 180.A SG ASP 185.A O no hydrogen 3.905 N/A CYS 180.A SG GLN 186.A OE1 no hydrogen 3.819 N/A CYS 180.A SG TRP 273.A O no hydrogen 3.816 N/A THR 181.A N GLU 184.A OE1 no hydrogen 2.816 N/A GLU 183.A N THR 181.A OG1 no hydrogen 3.086 N/A GLU 184.A N THR 181.A O no hydrogen 3.275 N/A ASP 185.A N ALA 275.A O no hydrogen 2.755 N/A GLN 186.A N GLN 252.A O no hydrogen 2.929 N/A GLN 186.A NE2 PRO 177.A O no hydrogen 3.036 N/A GLN 186.A NE2 THR 188.A OG1 no hydrogen 3.150 N/A ILE 187.A N TRP 273.A O no hydrogen 2.876 N/A THR 188.A N MET 250.A O no hydrogen 2.884 N/A THR 188.A OG1 GLN 252.A OE1 no hydrogen 2.922 N/A TRP 190.A N ASP 248.A O no hydrogen 2.988 N/A GLY 191.A N LEU 267.A O no hydrogen 3.227 N/A PHE 192.A N VAL 246.A O no hydrogen 2.904 N/A HIS 193.A N GLY 265.A O no hydrogen 2.615 N/A HIS 193.A ND1 TYR 204.A OH no hydrogen 2.427 N/A SER 194.A N ARG 244.A O no hydrogen 2.910 N/A SER 194.A OG GLN 226.A O no hydrogen 2.604 N/A ASP 196.A N ASP 195.A OD1 no hydrogen 2.630 N/A LYS 197.A N ASP 196.A OD1 no hydrogen 2.765 N/A GLN 199.A N GLN 199.A OE1 no hydrogen 2.753 N/A MET 200.A N ASP 196.A O no hydrogen 2.767 N/A LYS 201.A N LYS 197.A O no hydrogen 2.967 N/A ASN 202.A N THR 198.A O no hydrogen 2.910 N/A LEU 203.A N GLN 199.A O no hydrogen 2.867 N/A TYR 204.A N MET 200.A O no hydrogen 2.932 N/A TYR 204.A OH HIS 193.A ND1 no hydrogen 2.427 N/A GLY 205.A N LYS 201.A O no hydrogen 3.096 N/A ASN 208.A N ASP 206.A OD1 no hydrogen 2.679 N/A GLN 210.A N SER 225.A OG no hydrogen 2.816 N/A GLN 210.A NE2 ASP 206.A OD2 no hydrogen 3.150 N/A GLN 210.A NE2 ASN 208.A O no hydrogen 2.695 N/A LYS 211.A N GLN 263.A OE1 no hydrogen 3.244 N/A PHE 212.A N TYR 223.A O no hydrogen 2.886 N/A THR 213.A N VAL 261.A O no hydrogen 2.883 N/A THR 213.A OG1 HIS 222.A ND1 no hydrogen 2.718 N/A SER 214.A N THR 221.A O no hydrogen 2.914 N/A SER 214.A OG THR 221.A OG1 no hydrogen 2.627 N/A SER 215.A N THR 259.A O no hydrogen 2.926 N/A ALA 216.A N VAL 219.A O no hydrogen 3.134 N/A ASN 217.A ND2 VAL 251.A O no hydrogen 3.012 N/A VAL 219.A N ALA 216.A O no hydrogen 2.926 N/A THR 221.A N SER 214.A O no hydrogen 2.940 N/A THR 221.A OG1 SER 214.A OG no hydrogen 2.627 N/A HIS 222.A ND1 THR 213.A OG1 no hydrogen 2.718 N/A TYR 223.A N PHE 212.A O no hydrogen 2.828 N/A TYR 223.A OH ASP 248.A OD2 no hydrogen 2.702 N/A SER 225.A N GLN 210.A O no hydrogen 2.866 N/A SER 225.A OG GLN 210.A O no hydrogen 3.281 N/A GLN 226.A NE2 GLY 228.A O no hydrogen 2.975 N/A GLY 228.A N ASP 195.A O no hydrogen 3.053 N/A GLN 233.A NE2 ASP 236.A OD2 no hydrogen 2.622 N/A GLN 233.A NE2 LEU 239.A O no hydrogen 2.816 N/A GLY 237.A N CYS 94.A O no hydrogen 2.758 N/A GLY 238.A N ASP 236.A OD1 no hydrogen 3.421 N/A GLN 241.A N GLN 233.A OE1 no hydrogen 2.423 N/A SER 242.A OG ASP 195.A OD1 no hydrogen 2.853 N/A SER 242.A OG ASP 195.A OD2 no hydrogen 3.442 N/A ARG 244.A N SER 194.A O no hydrogen 3.045 N/A ARG 244.A NE PRO 231.A O no hydrogen 2.911 N/A ARG 244.A NH1 GLN 241.A O no hydrogen 3.340 N/A ARG 244.A NH1 GLY 243.A O no hydrogen 2.884 N/A ARG 244.A NH2 PRO 231.A O no hydrogen 2.674 N/A ILE 245.A N PRO 96.A O no hydrogen 3.265 N/A VAL 246.A N PHE 192.A O no hydrogen 2.911 N/A ASP 248.A N TRP 190.A O no hydrogen 2.825 N/A MET 250.A N THR 188.A O no hydrogen 2.853 N/A GLN 252.A N GLN 186.A O no hydrogen 2.855 N/A GLN 252.A NE2 VAL 176.A O no hydrogen 2.896 N/A GLN 252.A NE2 LYS 256.A O no hydrogen 2.807 N/A LYS 253.A NZ ASP 185.A OD1 no hydrogen 3.203 N/A LYS 253.A NZ ASP 185.A OD2 no hydrogen 2.652 N/A LYS 256.A N LYS 253.A O no hydrogen 2.984 N/A GLY 258.A N VAL 176.A O no hydrogen 2.874 N/A THR 259.A N SER 215.A O no hydrogen 2.915 N/A ILE 260.A N VAL 174.A O no hydrogen 2.936 N/A VAL 261.A N THR 213.A O no hydrogen 2.842 N/A TYR 262.A N LEU 172.A O no hydrogen 2.885 N/A TYR 262.A OH PRO 131.A O no hydrogen 2.864 N/A ARG 264.A N GLN 210.A OE1 no hydrogen 3.001 N/A ARG 264.A NE THR 167.A O no hydrogen 2.718 N/A ARG 264.A NH1 GLY 132.A O no hydrogen 3.414 N/A ARG 264.A NH2 THR 167.A O no hydrogen 2.955 N/A LEU 267.A N GLY 191.A O no hydrogen 2.730 N/A LEU 268.A N ALA 157.A O no hydrogen 2.963 N/A GLN 270.A N THR 155.A O no hydrogen 2.825 N/A GLN 270.A NE2 ILE 125.A O no hydrogen 2.734 N/A GLN 270.A NE2 PRO 269.A O no hydrogen 3.032 N/A LYS 271.A N ALA 154.A O no hydrogen 3.435 N/A LYS 271.A NZ ASN 123.A OD1 no hydrogen 2.622 N/A VAL 272.A N SER 120.A OG no hydrogen 2.875 N/A TRP 273.A N ILE 187.A O no hydrogen 2.915 N/A TRP 273.A NE1 ALA 66.A O no hydrogen 2.771 N/A CYS 274.A N ARG 118.A O no hydrogen 2.861 N/A ALA 275.A N ASP 185.A O no hydrogen 2.949 N/A SER 276.A N LYS 116.A O no hydrogen 2.915 N/A SER 279.A N GLY 113.A O no hydrogen 2.969 N/A SER 279.A OG SER 82.A OG no hydrogen 3.066 N/A SER 279.A OG ARG 112.A O no hydrogen 2.496 N/A LYS 280.A N LYS 80.A O no hydrogen 2.776 N/A ILE 282.A N SER 82.A O no hydrogen 3.017 N/A LYS 283.A N GLU 297.A OE2 no hydrogen 2.837 N/A GLY 284.A N LEU 84.A O no hydrogen 3.223 N/A ILE 289.A N PHE 41.A O no hydrogen 3.018 N/A ALA 292.A N ASN 43.A O no hydrogen 3.078 N/A ASP 293.A N ASN 303.A OD1 no hydrogen 2.805 N/A CYS 294.A N LEU 302.A O no hydrogen 2.848 N/A CYS 294.A SG ILE 317.A O no hydrogen 3.670 N/A LEU 295.A N ILE 317.A O no hydrogen 2.927 N/A HIS 296.A N GLY 300.A O no hydrogen 2.926 N/A HIS 296.A NE2 TYR 309.A OH no hydrogen 2.776 N/A GLU 297.A N LYS 315.A O no hydrogen 3.006 N/A LYS 298.A N HIS 296.A ND1 no hydrogen 3.067 N/A GLY 300.A N HIS 296.A O no hydrogen 2.850 N/A GLY 301.A N HIS 40.A O no hydrogen 2.907 N/A LEU 302.A N CYS 294.A O no hydrogen 2.893 N/A LYS 304.A N ASP 293.A OD2 no hydrogen 3.164 N/A LYS 306.A N SER 305.A OG no hydrogen 2.640 N/A TYR 308.A N LEU 32.A O no hydrogen 3.121 N/A TYR 309.A N ILE 322.A O no hydrogen 2.898 N/A TYR 309.A OH HIS 296.A NE2 no hydrogen 2.776 N/A THR 310.A N THR 34.A O no hydrogen 2.887 N/A THR 310.A OG1 THR 34.A O no hydrogen 3.442 N/A THR 310.A OG1 THR 35.A OG1 no hydrogen 2.717 N/A GLU 312.A N TYR 299.A OH no hydrogen 2.903 N/A ILE 317.A N LEU 295.A O no hydrogen 2.899 N/A ASN 319.A N ASP 293.A O no hydrogen 3.066 N/A ILE 322.A N PRO 307.A O no hydrogen 3.010 N/A TRP 323.A NE1 GLY 311.A O no hydrogen 3.021 N/A VAL 324.A N TYR 309.A O no hydrogen 2.880 N/A LYS 329.A NZ PRO 327.A O no hydrogen 3.474 N/A LEU 330.A N ILE 30.A O no hydrogen 2.837 N/A ASN 332.A N GLY 28.A O no hydrogen 2.841 N/A THR 334.A N THR 27.A OG1 no hydrogen 3.151 N/A LYS 335.A NZ GLN 21.A OE1 no hydrogen 2.378 N/A TYR 336.A N ASN 25.A O no hydrogen 2.870 N/A LYS 341.A NZ PRO 339.A O no hydrogen 3.059 N/A