Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4mhx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 2.A NE GLU 278.A OE2 no hydrogen 2.893 N/A ASN 3.A N ASP 243.A O no hydrogen 2.959 N/A ALA 4.A N PHE 149.A O no hydrogen 3.025 N/A LEU 5.A N LEU 245.A O no hydrogen 2.761 N/A LEU 6.A N LEU 151.A O no hydrogen 2.885 N/A LEU 7.A N ILE 247.A O no hydrogen 2.899 N/A LEU 8.A N VAL 153.A O no hydrogen 2.932 N/A ALA 9.A N THR 249.A O no hydrogen 2.908 N/A ASP 10.A N ASP 157.A O no hydrogen 3.130 N/A ASP 11.A N ASP 251.A OD1 no hydrogen 2.859 N/A GLY 13.A N GLU 15.A OE1 no hydrogen 2.974 N/A SER 16.A N PHE 14.A O no hydrogen 2.892 N/A GLY 17.A N THR 26.A OG1 no hydrogen 2.991 N/A ALA 18.A N ASP 30.A OD1 no hydrogen 2.799 N/A TYR 19.A N SER 16.A O no hydrogen 3.150 N/A TYR 19.A N SER 16.A OG no hydrogen 3.291 N/A TYR 19.A OH PHE 39.A O no hydrogen 2.627 N/A TYR 19.A OH LEU 272.A O no hydrogen 3.366 N/A ASN 20.A N GLY 17.A O no hydrogen 2.783 N/A ASN 21.A N SER 16.A O no hydrogen 3.016 N/A ASN 21.A ND2 TYR 218.A OH no hydrogen 3.044 N/A ALA 23.A N ASN 21.A OD1 no hydrogen 2.927 N/A ILE 24.A N ASN 21.A OD1 no hydrogen 3.186 N/A ALA 25.A N TYR 193.A OH no hydrogen 3.099 N/A THR 26.A OG1 ASP 30.A OD1 no hydrogen 3.157 N/A HIS 28.A N ASP 225.A OD2 no hydrogen 3.096 N/A LEU 29.A N ASP 225.A OD1 no hydrogen 2.599 N/A ASP 30.A N THR 26.A O no hydrogen 3.039 N/A ALA 31.A N PRO 27.A O no hydrogen 2.866 N/A LEU 32.A N HIS 28.A O no hydrogen 2.969 N/A ALA 33.A N LEU 29.A O no hydrogen 2.868 N/A ARG 34.A N ASP 30.A O no hydrogen 3.207 N/A ARG 34.A N ALA 31.A O no hydrogen 3.241 N/A ARG 35.A N LEU 32.A O no hydrogen 2.903 N/A SER 36.A N ALA 33.A O no hydrogen 3.116 N/A SER 36.A OG LEU 32.A O no hydrogen 2.526 N/A LEU 37.A N VAL 274.A O no hydrogen 2.772 N/A LEU 38.A N GLN 285.A O no hydrogen 2.994 N/A PHE 39.A N LEU 272.A O no hydrogen 2.954 N/A ARG 40.A N SER 287.A O no hydrogen 3.038 N/A ASN 41.A ND2 GLU 288.A O no hydrogen 2.642 N/A PHE 43.A N VAL 291.A O no hydrogen 2.827 N/A THR 44.A N THR 268.A O no hydrogen 2.762 N/A THR 44.A OG1 VAL 46.A O no hydrogen 2.937 N/A THR 44.A OG1 SER 51.A OG no hydrogen 3.115 N/A THR 44.A OG1 ASP 251.A O no hydrogen 3.419 N/A VAL 46.A N THR 44.A OG1 no hydrogen 3.247 N/A SER 47.A N GLN 343.A OE1 no hydrogen 3.032 N/A SER 47.A OG GLY 267.A O no hydrogen 2.786 N/A SER 48.A OG HIS 346.A ND1 no hydrogen 2.616 N/A SER 49.A OG HIS 103.A O no hydrogen 2.709 N/A SER 51.A N SER 48.A O no hydrogen 2.830 N/A SER 51.A OG THR 44.A OG1 no hydrogen 3.115 N/A SER 51.A OG ASP 251.A O no hydrogen 2.600 N/A ARG 52.A NE ASP 251.A OD2 no hydrogen 3.322 N/A ARG 52.A NH2 ASP 251.A OD2 no hydrogen 3.138 N/A ALA 53.A N SER 49.A O no hydrogen 2.929 N/A SER 54.A N PRO 50.A O no hydrogen 2.913 N/A SER 54.A OG PRO 50.A O no hydrogen 2.806 N/A SER 54.A OG LEU 59.A O no hydrogen 3.036 N/A LEU 55.A N SER 51.A O no hydrogen 2.808 N/A LEU 56.A N ARG 52.A O no hydrogen 2.923 N/A THR 57.A N SER 54.A O no hydrogen 3.356 N/A THR 57.A OG1 ALA 53.A O no hydrogen 2.733 N/A GLY 58.A N SER 54.A O no hydrogen 2.679 N/A LEU 59.A N THR 57.A OG1 no hydrogen 3.063 N/A GLN 61.A NE2 SER 342.A OG no hydrogen 2.950 N/A GLN 61.A NE2 SER 344.A OG no hydrogen 3.005 N/A HIS 62.A ND1 SER 342.A OG no hydrogen 2.715 N/A HIS 62.A NE2 THR 453.A OG1 no hydrogen 2.643 N/A GLN 63.A N PRO 60.A O no hydrogen 2.911 N/A GLN 63.A NE2 HIS 454.A ND1 no hydrogen 3.105 N/A ASN 64.A N PRO 60.A O no hydrogen 2.990 N/A ASN 64.A ND2 LEU 59.A O no hydrogen 3.160 N/A GLY 65.A N GLN 61.A O no hydrogen 3.126 N/A MET 66.A N ASN 64.A OD1 no hydrogen 2.938 N/A LEU 69.A N HIS 346.A O no hydrogen 2.789 N/A HIS 70.A N SER 49.A OG no hydrogen 3.017 N/A HIS 70.A ND1 PHE 76.A O no hydrogen 2.838 N/A GLN 71.A N GLN 71.A OE1 no hydrogen 2.876 N/A VAL 73.A N ASP 72.A OD1 no hydrogen 2.788 N/A HIS 74.A N GLN 71.A O no hydrogen 2.982 N/A HIS 75.A N GLN 71.A O no hydrogen 3.195 N/A PHE 76.A N LEU 69.A O no hydrogen 3.191 N/A ASN 77.A ND2 HIS 75.A O no hydrogen 3.654 N/A SER 78.A N GLY 105.A O no hydrogen 3.022 N/A SER 78.A OG ASN 64.A OD1 no hydrogen 3.111 N/A SER 78.A OG TYR 110.A OH no hydrogen 2.750 N/A PHE 79.A N ASN 64.A O no hydrogen 2.954 N/A VAL 82.A N PHE 79.A O no hydrogen 3.094 N/A ARG 83.A N TYR 311.A OH no hydrogen 3.203 N/A SER 84.A OG VAL 109.A O no hydrogen 2.459 N/A LEU 85.A N LEU 56.A O no hydrogen 2.694 N/A LEU 88.A N SER 84.A O no hydrogen 3.102 N/A LEU 89.A N LEU 85.A O no hydrogen 3.029 N/A SER 90.A N PRO 86.A O no hydrogen 3.122 N/A SER 90.A OG PRO 86.A O no hydrogen 3.392 N/A GLN 91.A N LEU 87.A O no hydrogen 3.077 N/A ALA 92.A N LEU 88.A O no hydrogen 3.072 N/A ALA 92.A N LEU 89.A O no hydrogen 3.183 N/A GLY 93.A N SER 90.A O no hydrogen 2.987 N/A VAL 94.A N LEU 89.A O no hydrogen 2.831 N/A ARG 95.A N PRO 148.A O no hydrogen 2.852 N/A ARG 95.A NH1 PHE 140.A O no hydrogen 2.627 N/A ARG 95.A NH1 THR 143.A OG1 no hydrogen 3.125 N/A ARG 95.A NH1 GLN 144.A OE1 no hydrogen 2.505 N/A ARG 95.A NH2 THR 143.A OG1 no hydrogen 2.837 N/A THR 96.A N ASP 113.A OD2 no hydrogen 2.976 N/A GLY 97.A N PHE 150.A O no hydrogen 2.931 N/A ILE 98.A N PHE 114.A O no hydrogen 2.885 N/A ILE 99.A N TYR 152.A O no hydrogen 2.991 N/A GLY 100.A N TYR 116.A O no hydrogen 2.806 N/A LYS 101.A N ALA 154.A O no hydrogen 2.954 N/A LYS 101.A NZ ASP 10.A OD1 no hydrogen 3.218 N/A LYS 101.A NZ ASP 10.A OD2 no hydrogen 2.863 N/A LYS 101.A NZ HIS 103.A ND1 no hydrogen 3.463 N/A LYS 102.A N GLU 118.A OE1 no hydrogen 2.839 N/A LYS 102.A NZ TYR 110.A O no hydrogen 2.820 N/A HIS 103.A N GLU 118.A OE2 no hydrogen 2.815 N/A HIS 103.A NE2 GLN 71.A OE1 no hydrogen 2.662 N/A VAL 109.A N PRO 106.A O no hydrogen 2.807 N/A TYR 110.A N PRO 106.A O no hydrogen 3.082 N/A TYR 110.A OH SER 78.A OG no hydrogen 2.750 N/A ASP 113.A N THR 96.A OG1 no hydrogen 3.065 N/A PHE 114.A N THR 96.A O no hydrogen 3.167 N/A TYR 116.A N ILE 98.A O no hydrogen 2.958 N/A THR 117.A N ASN 120.A OD1 no hydrogen 2.939 N/A GLU 118.A N GLU 118.A OE1 no hydrogen 2.791 N/A GLU 119.A N THR 117.A OG1 no hydrogen 3.056 N/A ASN 120.A N THR 117.A O no hydrogen 3.247 N/A ASN 120.A ND2 ALA 115.A O no hydrogen 3.034 N/A GLN 125.A N SER 122.A O no hydrogen 3.084 N/A VAL 126.A N SER 122.A O no hydrogen 2.970 N/A ARG 128.A N LEU 124.A O no hydrogen 3.170 N/A ARG 128.A NH1 ASP 157.A OD1 no hydrogen 2.618 N/A ARG 128.A NH1 HIS 159.A O no hydrogen 3.232 N/A ARG 128.A NH2 HIS 159.A O no hydrogen 3.101 N/A ASN 129.A N LEU 124.A O no hydrogen 2.970 N/A ASN 129.A ND2 GLN 125.A OE1 no hydrogen 2.891 N/A THR 131.A OG1 ASP 187.A OD2 no hydrogen 2.569 N/A ARG 132.A N ASN 129.A OD1 no hydrogen 3.307 N/A ILE 133.A N ASN 129.A O no hydrogen 2.971 N/A LYS 134.A N ILE 130.A O no hydrogen 2.866 N/A LYS 134.A NZ ASP 187.A OD2 no hydrogen 2.905 N/A LEU 135.A N THR 131.A O no hydrogen 2.925 N/A LEU 136.A N ARG 132.A O no hydrogen 2.953 N/A VAL 137.A N ILE 133.A O no hydrogen 2.937 N/A ARG 138.A N LYS 134.A O no hydrogen 2.962 N/A ARG 138.A NE GLU 234.A OE1 no hydrogen 2.869 N/A ARG 138.A NH2 GLU 234.A OE2 no hydrogen 3.054 N/A LYS 139.A N LEU 135.A O no hydrogen 2.939 N/A LYS 139.A NZ TYR 116.A OH no hydrogen 2.781 N/A PHE 140.A N LEU 136.A O no hydrogen 2.893 N/A LEU 141.A N VAL 137.A O no hydrogen 2.941 N/A GLN 142.A N ARG 138.A O no hydrogen 2.852 N/A THR 143.A N PHE 140.A O no hydrogen 3.217 N/A THR 143.A OG1 LYS 139.A O no hydrogen 2.967 N/A THR 143.A OG1 PHE 140.A O no hydrogen 2.965 N/A GLN 144.A N LEU 141.A O no hydrogen 3.164 N/A GLN 144.A NE2 ARG 147.A O no hydrogen 3.357 N/A PHE 149.A N ASN 3.A OD1 no hydrogen 2.852 N/A PHE 150.A N ARG 95.A O no hydrogen 2.740 N/A LEU 151.A N ALA 4.A O no hydrogen 2.971 N/A TYR 152.A N GLY 97.A O no hydrogen 2.912 N/A VAL 153.A N LEU 6.A O no hydrogen 2.806 N/A ALA 154.A N ILE 99.A O no hydrogen 2.887 N/A PHE 155.A N LEU 8.A O no hydrogen 2.934 N/A HIS 156.A N GLY 127.A O no hydrogen 2.835 N/A HIS 156.A ND1 ASP 10.A OD2 no hydrogen 2.906 N/A HIS 159.A N HIS 156.A O no hydrogen 3.086 N/A HIS 159.A ND1 ARG 160.A O no hydrogen 2.804 N/A ARG 160.A NE PRO 255.A O no hydrogen 2.872 N/A ARG 160.A NH1 ASP 213.A OD1 no hydrogen 3.009 N/A ARG 160.A NH1 ASP 213.A OD2 no hydrogen 3.269 N/A ARG 160.A NH2 ASP 213.A OD2 no hydrogen 2.852 N/A ARG 160.A NH2 PRO 255.A O no hydrogen 2.993 N/A CYS 161.A N THR 170.A O no hydrogen 2.909 N/A GLN 165.A N CYS 161.A O no hydrogen 2.705 N/A GLN 167.A N GLN 167.A OE1 no hydrogen 2.435 N/A GLN 167.A NE2 GLN 165.A OE1 no hydrogen 3.239 N/A TYR 168.A N GLN 165.A O no hydrogen 3.153 N/A GLY 169.A N PRO 166.A O no hydrogen 2.867 N/A THR 170.A OG1 ASP 213.A OD1 no hydrogen 2.957 N/A PHE 171.A N GLU 173.A OE1 no hydrogen 2.968 N/A CYS 172.A N GLY 169.A O no hydrogen 3.139 N/A GLU 173.A N GLU 173.A OE1 no hydrogen 2.867 N/A LYS 174.A N TYR 168.A O no hydrogen 2.908 N/A PHE 175.A N CYS 172.A O no hydrogen 3.216 N/A GLY 176.A N MET 182.A O no hydrogen 2.842 N/A ASN 177.A N LYS 174.A O no hydrogen 3.244 N/A GLY 178.A N GLY 183.A O no hydrogen 2.816 N/A GLU 179.A N ASN 177.A OD1 no hydrogen 2.593 N/A MET 182.A N GLU 179.A O no hydrogen 2.949 N/A ILE 185.A N GLY 176.A O no hydrogen 3.041 N/A ASP 187.A N THR 131.A OG1 no hydrogen 3.233 N/A TRP 188.A N ILE 185.A O no hydrogen 3.012 N/A THR 189.A N GLN 226.A OE1 no hydrogen 2.986 N/A GLN 191.A NE2 ALA 25.A O no hydrogen 3.252 N/A ASP 197.A N ASP 194.A O no hydrogen 3.007 N/A LEU 199.A N TYR 218.A OH no hydrogen 3.078 N/A VAL 204.A N PRO 201.A O no hydrogen 3.055 N/A ASN 206.A N GLY 400.A O no hydrogen 3.366 N/A THR 207.A OG1 ASP 388.A OD2 no hydrogen 2.949 N/A ALA 210.A N THR 207.A OG1 no hydrogen 3.248 N/A ARG 211.A N THR 207.A O no hydrogen 2.861 N/A ARG 211.A NE ASN 206.A OD1 no hydrogen 2.650 N/A ALA 212.A N PRO 208.A O no hydrogen 2.910 N/A ASP 213.A N ALA 209.A O no hydrogen 3.015 N/A LEU 214.A N ALA 210.A O no hydrogen 2.921 N/A ALA 215.A N ARG 211.A O no hydrogen 2.950 N/A ALA 216.A N ALA 212.A O no hydrogen 3.208 N/A GLN 217.A N ASP 213.A O no hydrogen 3.051 N/A TYR 218.A N LEU 214.A O no hydrogen 2.901 N/A THR 219.A N ALA 215.A O no hydrogen 3.300 N/A THR 219.A OG1 GLN 191.A O no hydrogen 2.768 N/A THR 219.A OG1 ALA 215.A O no hydrogen 3.338 N/A THR 220.A N ALA 216.A O no hydrogen 3.268 N/A THR 220.A OG1 PHE 171.A O no hydrogen 2.911 N/A VAL 221.A N GLN 217.A O no hydrogen 2.795 N/A GLY 222.A N TYR 218.A O no hydrogen 2.874 N/A ARG 223.A N THR 219.A O no hydrogen 3.167 N/A ARG 223.A NE ASP 157.A OD2 no hydrogen 2.882 N/A ARG 223.A NH1 CYS 172.A O no hydrogen 3.135 N/A ARG 223.A NH2 ASP 157.A OD1 no hydrogen 2.975 N/A ARG 223.A NH2 CYS 172.A O no hydrogen 2.872 N/A MET 224.A N THR 220.A O no hydrogen 3.012 N/A ASP 225.A N VAL 221.A O no hydrogen 2.857 N/A GLN 226.A N GLY 222.A O no hydrogen 3.034 N/A GLN 226.A NE2 THR 189.A O no hydrogen 2.850 N/A GLN 226.A NE2 GLN 191.A OE1 no hydrogen 3.112 N/A GLN 226.A NE2 GLY 222.A O no hydrogen 3.619 N/A GLY 227.A N ARG 223.A O no hydrogen 3.014 N/A VAL 228.A N MET 224.A O no hydrogen 2.963 N/A GLY 229.A N ASP 225.A O no hydrogen 3.105 N/A LEU 230.A N GLN 226.A O no hydrogen 3.016 N/A VAL 231.A N GLY 227.A O no hydrogen 3.013 N/A LEU 232.A N VAL 228.A O no hydrogen 3.055 N/A GLN 233.A N GLY 229.A O no hydrogen 2.940 N/A GLN 233.A NE2 ASP 237.A OD1 no hydrogen 2.658 N/A GLU 234.A N LEU 230.A O no hydrogen 2.976 N/A LEU 235.A N VAL 231.A O no hydrogen 3.237 N/A ARG 236.A N LEU 232.A O no hydrogen 3.018 N/A ARG 236.A NH1 GLN 233.A OE1 no hydrogen 2.758 N/A ASP 237.A N GLN 233.A O no hydrogen 2.808 N/A ALA 238.A N GLU 234.A O no hydrogen 2.961 N/A GLY 239.A N ARG 236.A O no hydrogen 2.797 N/A VAL 240.A N LEU 235.A O no hydrogen 2.857 N/A LEU 241.A N LEU 235.A O no hydrogen 3.088 N/A ASP 243.A N VAL 240.A O no hydrogen 2.821 N/A THR 244.A N LEU 241.A O no hydrogen 3.194 N/A THR 244.A OG1 VAL 240.A O no hydrogen 2.899 N/A LEU 245.A N ASN 3.A O no hydrogen 2.933 N/A VAL 246.A N SER 275.A O no hydrogen 2.979 N/A ILE 247.A N LEU 5.A O no hydrogen 3.001 N/A PHE 248.A N LEU 273.A O no hydrogen 3.011 N/A THR 249.A N LEU 7.A O no hydrogen 3.028 N/A SER 250.A OG ALA 9.A O no hydrogen 3.313 N/A SER 250.A OG GLY 12.A O no hydrogen 2.857 N/A SER 250.A OG ASN 252.A O no hydrogen 3.300 N/A SER 250.A OG GLU 270.A OE1 no hydrogen 3.217 N/A ASP 251.A N ALA 9.A O no hydrogen 3.317 N/A ASN 252.A ND2 ASP 11.A OD1 no hydrogen 2.558 N/A ASN 252.A ND2 GLY 253.A O no hydrogen 3.091 N/A GLY 253.A N GLY 267.A O no hydrogen 2.966 N/A PHE 256.A N ILE 254.A O no hydrogen 2.877 N/A SER 258.A N TYR 408.A OH no hydrogen 3.060 N/A SER 258.A OG TYR 402.A OH no hydrogen 2.814 N/A GLY 259.A N PHE 256.A O no hydrogen 2.882 N/A ARG 260.A N ILE 254.A O no hydrogen 2.922 N/A ARG 260.A NH1 HIS 159.A NE2 no hydrogen 3.376 N/A THR 261.A N SER 47.A O no hydrogen 2.966 N/A THR 261.A N SER 47.A OG no hydrogen 2.888 N/A THR 261.A OG1 ARG 260.A O no hydrogen 2.576 N/A ASN 262.A N GLY 259.A O no hydrogen 2.980 N/A ASN 262.A ND2 GLY 259.A O no hydrogen 3.161 N/A ASN 262.A ND2 ARG 260.A O no hydrogen 3.689 N/A ASN 262.A ND2 TYR 408.A OH no hydrogen 3.058 N/A TYR 264.A OH GLU 415.A OE2 no hydrogen 2.554 N/A GLY 267.A N TYR 264.A O no hydrogen 2.893 N/A THR 268.A N TYR 264.A O no hydrogen 3.204 N/A THR 268.A N TRP 265.A O no hydrogen 3.299 N/A THR 268.A OG1 TYR 264.A O no hydrogen 3.278 N/A ALA 269.A N TRP 265.A O no hydrogen 2.989 N/A GLU 270.A N ALA 42.A O no hydrogen 2.950 N/A LEU 272.A N TYR 19.A OH no hydrogen 2.995 N/A LEU 273.A N PHE 248.A O no hydrogen 2.997 N/A VAL 274.A N LEU 37.A O no hydrogen 2.954 N/A SER 275.A N VAL 246.A O no hydrogen 2.852 N/A SER 275.A OG ARG 35.A O no hydrogen 2.399 N/A SER 276.A OG HIS 279.A ND1 no hydrogen 2.727 N/A GLU 278.A N SER 276.A OG no hydrogen 3.145 N/A HIS 279.A N SER 276.A O no hydrogen 3.253 N/A HIS 279.A ND1 SER 276.A OG no hydrogen 2.727 N/A ARG 282.A NE ALA 329.A O no hydrogen 3.009 N/A ARG 282.A NH1 GLN 285.A OE1 no hydrogen 3.294 N/A ARG 282.A NH2 ALA 329.A O no hydrogen 2.822 N/A ARG 282.A NH2 GLU 333.A OE1 no hydrogen 2.750 N/A TRP 283.A N PRO 280.A O no hydrogen 3.111 N/A TRP 283.A NE1 SER 276.A O no hydrogen 3.102 N/A GLY 284.A N SER 36.A O no hydrogen 2.713 N/A GLN 285.A N ARG 282.A O no hydrogen 2.988 N/A SER 287.A N LEU 38.A O no hydrogen 2.751 N/A SER 287.A OG GLU 333.A OE1 no hydrogen 2.505 N/A SER 287.A OG GLU 333.A OE2 no hydrogen 3.064 N/A GLU 288.A N GLU 333.A OE2 no hydrogen 2.771 N/A ALA 289.A N SER 287.A OG no hydrogen 3.333 N/A TYR 290.A N TRP 336.A O no hydrogen 2.916 N/A VAL 291.A N ASN 41.A O no hydrogen 2.990 N/A SER 292.A N ASP 295.A OD2 no hydrogen 3.028 N/A LEU 293.A N PHE 43.A O no hydrogen 2.870 N/A LEU 294.A N SER 292.A OG no hydrogen 3.180 N/A ASP 295.A N SER 292.A O no hydrogen 2.773 N/A LEU 296.A N LEU 293.A O no hydrogen 3.208 N/A THR 297.A OG1 LEU 55.A O no hydrogen 2.672 N/A THR 299.A N ASP 295.A O no hydrogen 2.908 N/A THR 299.A OG1 ASP 295.A O no hydrogen 2.650 N/A ILE 300.A N LEU 296.A O no hydrogen 2.836 N/A LEU 301.A N THR 297.A O no hydrogen 2.973 N/A ASP 302.A N PRO 298.A O no hydrogen 3.115 N/A TRP 303.A N THR 299.A O no hydrogen 3.007 N/A TRP 303.A NE1 ASN 3.A O no hydrogen 2.768 N/A PHE 304.A N ILE 300.A O no hydrogen 3.116 N/A SER 305.A N ASP 302.A O no hydrogen 3.000 N/A ILE 306.A N LEU 301.A O no hydrogen 2.821 N/A TYR 311.A OH TYR 308.A OH no hydrogen 2.627 N/A LYS 317.A N PHE 314.A O no hydrogen 3.185 N/A ILE 319.A N TYR 311.A O no hydrogen 2.834 N/A ARG 324.A N ASP 295.A OD1 no hydrogen 2.731 N/A SER 325.A OG ASP 302.A OD2 no hydrogen 2.667 N/A LEU 326.A N THR 299.A OG1 no hydrogen 2.845 N/A LEU 327.A N SER 325.A OG no hydrogen 3.206 N/A ALA 329.A N LEU 326.A O no hydrogen 2.952 N/A LEU 330.A N LEU 327.A O no hydrogen 3.187 N/A GLU 331.A N PRO 328.A O no hydrogen 2.935 N/A ALA 332.A N PRO 328.A O no hydrogen 3.161 N/A VAL 339.A N GLN 358.A O no hydrogen 3.028 N/A GLY 341.A N SER 356.A O no hydrogen 2.721 N/A SER 342.A N SER 45.A O no hydrogen 2.811 N/A SER 342.A OG HIS 62.A ND1 no hydrogen 2.715 N/A GLN 343.A N MET 354.A O no hydrogen 2.980 N/A GLN 343.A NE2 THR 261.A O no hydrogen 3.003 N/A HIS 345.A N TYR 67.A O no hydrogen 2.933 N/A HIS 346.A ND1 SER 48.A OG no hydrogen 2.616 N/A VAL 348.A N HIS 74.A ND1 no hydrogen 3.151 N/A MET 350.A N GLU 347.A O no hydrogen 2.846 N/A MET 354.A N GLN 343.A O no hydrogen 2.822 N/A ARG 355.A N HIS 366.A O no hydrogen 2.904 N/A ARG 355.A NE ASP 455.A OD2 no hydrogen 2.603 N/A ARG 355.A NH1 GLN 343.A O no hydrogen 2.780 N/A ARG 355.A NH1 MET 354.A O no hydrogen 3.031 N/A ARG 355.A NH2 SER 344.A OG no hydrogen 3.410 N/A ARG 355.A NH2 ASP 455.A OD1 no hydrogen 2.902 N/A ARG 355.A NH2 ASP 455.A OD2 no hydrogen 3.269 N/A SER 356.A N GLY 341.A O no hydrogen 2.908 N/A VAL 357.A N LEU 364.A O no hydrogen 3.101 N/A GLN 358.A N VAL 339.A O no hydrogen 2.782 N/A GLN 358.A NE2 ARG 360.A O no hydrogen 2.724 N/A HIS 359.A N PHE 362.A O no hydrogen 2.860 N/A ARG 360.A N ALA 337.A O no hydrogen 2.854 N/A PHE 362.A N HIS 359.A O no hydrogen 3.064 N/A ARG 363.A N TYR 417.A O no hydrogen 2.872 N/A ARG 363.A NH2 LEU 263.A O no hydrogen 2.469 N/A LEU 364.A N VAL 357.A O no hydrogen 2.991 N/A VAL 365.A N GLU 415.A O no hydrogen 2.757 N/A HIS 366.A N ARG 355.A O no hydrogen 2.713 N/A ASN 367.A N ARG 413.A O no hydrogen 2.803 N/A ASN 367.A ND2 ALA 412.A O no hydrogen 2.744 N/A ASN 367.A ND2 GLU 415.A OE1 no hydrogen 2.950 N/A LEU 368.A N PRO 353.A O no hydrogen 3.004 N/A MET 372.A N ASN 369.A O no hydrogen 3.091 N/A PHE 374.A N TYR 409.A O no hydrogen 2.864 N/A GLN 378.A N GLU 347.A OE2 no hydrogen 2.964 N/A PHE 380.A N ASP 377.A OD2 no hydrogen 3.181 N/A TYR 381.A N ASP 377.A O no hydrogen 3.076 N/A SER 383.A N PHE 380.A O no hydrogen 2.903 N/A SER 383.A OG PHE 380.A O no hydrogen 2.559 N/A THR 385.A N ASP 213.A OD2 no hydrogen 3.285 N/A THR 385.A OG1 ASP 213.A OD2 no hydrogen 2.652 N/A PHE 386.A N SER 383.A OG no hydrogen 2.866 N/A GLN 387.A N SER 383.A O no hydrogen 2.896 N/A GLN 387.A NE2 TYR 381.A O no hydrogen 2.797 N/A ASP 388.A N PRO 384.A O no hydrogen 2.945 N/A LEU 389.A N THR 385.A O no hydrogen 3.061 N/A LEU 390.A N PHE 386.A O no hydrogen 2.890 N/A ASN 391.A N GLN 387.A O no hydrogen 2.778 N/A ARG 392.A N ASP 388.A O no hydrogen 2.999 N/A ARG 392.A NE ASP 388.A OD1 no hydrogen 2.975 N/A ARG 392.A NE ASP 388.A OD2 no hydrogen 3.485 N/A ARG 392.A NH1 PRO 398.A O no hydrogen 2.875 N/A THR 393.A N LEU 389.A O no hydrogen 2.967 N/A THR 393.A OG1 LEU 389.A O no hydrogen 2.849 N/A THR 394.A N LEU 390.A O no hydrogen 3.065 N/A THR 394.A OG1 LEU 390.A O no hydrogen 3.385 N/A THR 394.A OG1 ASN 391.A O no hydrogen 3.119 N/A ALA 395.A N ASN 391.A O no hydrogen 2.989 N/A GLN 397.A N ARG 392.A O no hydrogen 3.036 N/A TRP 401.A N THR 399.A OG1 no hydrogen 3.161 N/A TRP 401.A NE1 PHE 203.A O no hydrogen 2.909 N/A TYR 402.A OH SER 258.A OG no hydrogen 2.814 N/A HIS 407.A N ASP 404.A O no hydrogen 3.075 N/A TYR 408.A N ASP 404.A O no hydrogen 3.058 N/A TYR 409.A N LEU 405.A O no hydrogen 2.856 N/A TYR 410.A N ARG 406.A O no hydrogen 2.847 N/A ARG 411.A NE TYR 408.A O no hydrogen 2.876 N/A ARG 411.A NH1 ASN 262.A OD1 no hydrogen 2.943 N/A ARG 411.A NH2 ASN 262.A OD1 no hydrogen 2.795 N/A ARG 411.A NH2 TYR 408.A O no hydrogen 3.197 N/A ARG 413.A NE HIS 366.A NE2 no hydrogen 3.014 N/A ARG 413.A NH1 ARG 481.A O no hydrogen 2.880 N/A ARG 413.A NH2 ASP 462.A OD1 no hydrogen 3.413 N/A ARG 413.A NH2 ARG 481.A O no hydrogen 3.430 N/A GLU 415.A N VAL 365.A O no hydrogen 2.926 N/A LEU 416.A N ASN 428.A OD1 no hydrogen 2.937 N/A TYR 417.A N ARG 363.A O no hydrogen 2.783 N/A TYR 417.A OH GLU 415.A OE2 no hydrogen 2.914 N/A ARG 419.A N HIS 361.A O no hydrogen 2.879 N/A SER 420.A N ASP 418.A OD1 no hydrogen 2.913 N/A SER 420.A OG ASP 418.A OD1 no hydrogen 2.770 N/A SER 420.A OG ASP 418.A OD2 no hydrogen 3.510 N/A ARG 421.A N ASP 418.A O no hydrogen 3.182 N/A ASP 422.A N ASP 418.A O no hydrogen 2.721 N/A GLU 425.A N ASP 422.A O no hydrogen 2.947 N/A THR 426.A N ASP 422.A OD1 no hydrogen 2.998 N/A THR 426.A OG1 ASP 422.A OD1 no hydrogen 3.414 N/A GLN 427.A N ASP 422.A OD2 no hydrogen 3.356 N/A ASN 428.A ND2 TRP 414.A O no hydrogen 3.055 N/A LEU 429.A N LEU 416.A O no hydrogen 2.781 N/A ALA 430.A N ASN 428.A OD1 no hydrogen 2.905 N/A ASP 432.A N LEU 429.A O no hydrogen 3.016 N/A ARG 434.A N ASP 432.A OD1 no hydrogen 3.025 N/A ARG 434.A NE ASP 432.A OD1 no hydrogen 3.107 N/A ARG 434.A NE ASP 432.A OD2 no hydrogen 3.332 N/A ARG 434.A NH2 ASP 432.A OD2 no hydrogen 2.734 N/A PHE 435.A N ASP 432.A O no hydrogen 2.851 N/A ALA 436.A N PRO 433.A O no hydrogen 3.167 N/A LEU 439.A N PHE 435.A O no hydrogen 3.029 N/A GLU 440.A N ALA 436.A O no hydrogen 2.932 N/A MET 441.A N GLN 437.A O no hydrogen 2.992 N/A LEU 442.A N LEU 438.A O no hydrogen 2.838 N/A ARG 443.A N LEU 439.A O no hydrogen 2.939 N/A ASP 444.A N GLU 440.A O no hydrogen 3.059 N/A GLN 445.A N MET 441.A O no hydrogen 3.156 N/A LEU 446.A N LEU 442.A O no hydrogen 2.978 N/A ALA 447.A N ARG 443.A O no hydrogen 2.994 N/A LYS 448.A N ASP 444.A O no hydrogen 3.077 N/A TRP 449.A N GLN 445.A O no hydrogen 3.179 N/A GLN 450.A N LEU 446.A O no hydrogen 3.031 N/A GLN 450.A NE2 ASP 455.A OD2 no hydrogen 2.849 N/A TRP 451.A N ALA 447.A O no hydrogen 3.021 N/A GLU 452.A N LYS 448.A O no hydrogen 3.087 N/A THR 453.A N TRP 449.A O no hydrogen 2.827 N/A THR 453.A OG1 HIS 62.A NE2 no hydrogen 2.643 N/A THR 453.A OG1 TRP 449.A O no hydrogen 2.697 N/A THR 453.A OG1 GLN 450.A O no hydrogen 3.497 N/A HIS 454.A N TRP 451.A O no hydrogen 2.880 N/A ASP 455.A N GLN 450.A O no hydrogen 2.921 N/A TRP 457.A N ASP 455.A OD1 no hydrogen 2.936 N/A VAL 458.A N ASP 455.A O no hydrogen 3.102 N/A ALA 460.A N TRP 457.A O no hydrogen 3.040 N/A GLY 463.A N CYS 459.A O no hydrogen 3.057 N/A VAL 464.A N GLN 474.A O no hydrogen 2.801 N/A GLU 466.A N GLN 472.A O no hydrogen 2.843 N/A LEU 469.A N GLU 466.A O no hydrogen 3.421 N/A GLN 474.A N VAL 464.A O no hydrogen 2.897 N/A GLN 474.A NE2 PRO 471.A O no hydrogen 2.914 N/A LEU 476.A N ASP 462.A O no hydrogen 3.186 N/A ASN 478.A ND2 PRO 461.A O no hydrogen 3.107 N/A