Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4n06_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 3.A NE ASP 300.A OD1 no hydrogen 3.383 N/A ARG 3.A NE ASP 300.A OD2 no hydrogen 3.093 N/A ARG 3.A NH1 GLN 39.A OE1 no hydrogen 2.659 N/A ARG 3.A NH1 GLU 218.A OE1 no hydrogen 3.149 N/A ARG 3.A NH2 GLU 218.A OE2 no hydrogen 2.745 N/A ARG 3.A NH2 ASP 300.A OD1 no hydrogen 3.041 N/A LEU 4.A N GLN 39.A O no hydrogen 2.938 N/A VAL 6.A N LEU 41.A O no hydrogen 2.769 N/A LYS 11.A NZ GLU 24.A OE1 no hydrogen 3.535 N/A TYR 12.A N LYS 23.A O no hydrogen 2.927 N/A LEU 13.A N ALA 47.A O no hydrogen 2.819 N/A GLY 14.A N VAL 21.A O no hydrogen 2.897 N/A GLU 16.A N LEU 19.A O no hydrogen 2.982 N/A LEU 19.A N GLU 16.A O no hydrogen 3.024 N/A VAL 21.A N GLY 14.A O no hydrogen 2.894 N/A VAL 22.A N ARG 30.A O no hydrogen 2.869 N/A LYS 23.A N TYR 12.A O no hydrogen 2.908 N/A LYS 23.A NZ GLU 16.A OE1 no hydrogen 3.046 N/A LYS 23.A NZ GLU 16.A OE2 no hydrogen 3.516 N/A GLU 24.A N LYS 27.A O no hydrogen 2.913 N/A GLY 26.A N TYR 12.A OH no hydrogen 3.038 N/A LYS 27.A N GLU 24.A O no hydrogen 3.023 N/A LEU 29.A N VAL 22.A O no hydrogen 2.653 N/A ARG 30.A N VAL 22.A O no hydrogen 3.001 N/A VAL 32.A N ILE 20.A O no hydrogen 2.891 N/A ARG 33.A NE ASP 36.A OD2 no hydrogen 2.727 N/A ASP 36.A N ARG 33.A O no hydrogen 3.053 N/A LEU 37.A N PRO 34.A O no hydrogen 2.974 N/A LYS 38.A NZ ASP 300.A OD1 no hydrogen 3.147 N/A GLN 39.A NE2 ASP 62.A OD1 no hydrogen 3.182 N/A VAL 40.A N ASP 62.A O no hydrogen 2.887 N/A LEU 41.A N LEU 4.A O no hydrogen 2.734 N/A ILE 42.A N VAL 64.A O no hydrogen 2.892 N/A ILE 43.A N VAL 6.A O no hydrogen 2.903 N/A GLY 44.A N LEU 66.A O no hydrogen 2.938 N/A ALA 46.A N ILE 43.A O no hydrogen 3.177 N/A ALA 47.A N LYS 11.A O no hydrogen 3.159 N/A SER 49.A N LEU 13.A O no hydrogen 3.141 N/A SER 49.A OG LEU 13.A O no hydrogen 3.459 N/A ALA 52.A N SER 49.A OG no hydrogen 3.042 N/A ILE 53.A N SER 49.A O no hydrogen 3.142 N/A LYS 54.A N SER 50.A O no hydrogen 2.917 N/A LEU 55.A N ASP 51.A O no hydrogen 2.929 N/A LEU 56.A N ALA 52.A O no hydrogen 2.931 N/A LEU 57.A N ILE 53.A O no hydrogen 2.896 N/A LYS 58.A N LYS 54.A O no hydrogen 2.904 N/A ASN 59.A N LEU 55.A O no hydrogen 3.215 N/A ASN 59.A N LEU 56.A O no hydrogen 3.106 N/A ASN 59.A ND2 LEU 55.A O no hydrogen 2.777 N/A ARG 60.A N LEU 57.A O no hydrogen 3.105 N/A VAL 61.A N LEU 56.A O no hydrogen 2.746 N/A ASP 62.A N LYS 38.A O no hydrogen 3.113 N/A VAL 63.A N LEU 76.A O no hydrogen 2.958 N/A VAL 64.A N VAL 40.A O no hydrogen 2.927 N/A PHE 65.A N GLY 74.A O no hydrogen 2.964 N/A LEU 66.A N ILE 42.A O no hydrogen 2.899 N/A ASP 67.A N GLU 71.A O no hydrogen 3.342 N/A GLY 70.A N ASP 67.A O no hydrogen 2.883 N/A LEU 73.A N PHE 65.A O no hydrogen 2.875 N/A ARG 75.A NE GLU 224.A OE2 no hydrogen 2.783 N/A ARG 75.A NH1 ASP 62.A OD2 no hydrogen 2.600 N/A ARG 75.A NH2 GLU 224.A OE2 no hydrogen 2.605 N/A LEU 76.A N VAL 63.A O no hydrogen 2.885 N/A THR 83.A OG1 GLY 227.A O no hydrogen 2.399 N/A ARG 87.A N THR 83.A O no hydrogen 2.989 N/A ARG 88.A N ALA 84.A O no hydrogen 2.922 N/A GLU 89.A N LYS 85.A O no hydrogen 2.975 N/A GLN 90.A N THR 86.A O no hydrogen 2.882 N/A GLN 90.A NE2 ASP 229.A O no hydrogen 2.738 N/A GLN 90.A NE2 ALA 232.A O no hydrogen 2.813 N/A TYR 91.A N ARG 87.A O no hydrogen 2.903 N/A TYR 91.A OH ASP 229.A OD2 no hydrogen 2.887 N/A LEU 92.A N ARG 88.A O no hydrogen 2.930 N/A ALA 93.A N GLU 89.A O no hydrogen 2.907 N/A TYR 94.A OH ASP 156.A OD1 no hydrogen 2.774 N/A GLY 95.A N LEU 92.A O no hydrogen 3.064 N/A ASP 96.A N ALA 93.A O no hydrogen 3.208 N/A ARG 98.A N ASP 96.A OD2 no hydrogen 3.141 N/A ARG 98.A NE ASP 96.A OD1 no hydrogen 3.212 N/A ARG 98.A NE ASP 96.A OD2 no hydrogen 2.994 N/A ARG 98.A NH1 GLU 89.A OE1 no hydrogen 2.967 N/A ARG 98.A NH1 LEU 327.A O no hydrogen 3.159 N/A ARG 98.A NH2 ASP 96.A OD1 no hydrogen 2.898 N/A GLY 99.A N ALA 93.A O no hydrogen 3.259 N/A GLY 99.A N ASP 96.A O no hydrogen 3.365 N/A HIS 101.A N LYS 97.A O no hydrogen 2.920 N/A HIS 101.A NE2 TYR 333.A O no hydrogen 2.810 N/A LEU 102.A N ARG 98.A O no hydrogen 2.933 N/A ALA 103.A N GLY 99.A O no hydrogen 2.965 N/A LYS 104.A N VAL 100.A O no hydrogen 2.925 N/A LYS 104.A NZ ASP 149.A O no hydrogen 3.261 N/A LYS 104.A NZ VAL 151.A O no hydrogen 2.718 N/A GLU 105.A N HIS 101.A O no hydrogen 2.936 N/A PHE 106.A N LEU 102.A O no hydrogen 2.960 N/A ILE 107.A N ALA 103.A O no hydrogen 3.000 N/A LYS 108.A N LYS 104.A O no hydrogen 2.908 N/A LYS 108.A NZ ASP 149.A OD1 no hydrogen 3.162 N/A ALA 109.A N GLU 105.A O no hydrogen 2.939 N/A LYS 110.A N PHE 106.A O no hydrogen 2.980 N/A LYS 110.A NZ GLU 166.A OE1 no hydrogen 3.287 N/A ASN 112.A N ALA 109.A O no hydrogen 2.958 N/A ASN 112.A ND2 ALA 109.A O no hydrogen 2.717 N/A ASN 112.A ND2 PHE 336.A O no hydrogen 2.978 N/A GLN 113.A N LYS 110.A O no hydrogen 2.969 N/A GLN 113.A NE2 SER 170.A OG no hydrogen 3.411 N/A ILE 115.A N ASN 112.A O no hydrogen 2.988 N/A LEU 116.A N GLN 113.A O no hydrogen 2.992 N/A ASN 118.A N ALA 114.A O no hydrogen 2.984 N/A LEU 119.A N ILE 115.A O no hydrogen 2.927 N/A ALA 120.A N LEU 116.A O no hydrogen 2.925 N/A LYS 121.A N THR 117.A O no hydrogen 2.941 N/A ALA 122.A N ASN 118.A O no hydrogen 2.997 N/A ARG 123.A N ALA 120.A O no hydrogen 3.070 N/A ASN 127.A N ARG 123.A O no hydrogen 2.912 N/A VAL 130.A N ASN 127.A OD1 no hydrogen 3.291 N/A ALA 131.A N ASN 127.A O no hydrogen 3.082 N/A GLU 132.A N PRO 128.A O no hydrogen 2.933 N/A SER 133.A N GLU 129.A O no hydrogen 2.957 N/A SER 133.A OG GLU 129.A O no hydrogen 3.010 N/A LEU 134.A N VAL 130.A O no hydrogen 2.902 N/A LEU 135.A N ALA 131.A O no hydrogen 2.950 N/A LYS 136.A N GLU 132.A O no hydrogen 2.950 N/A LYS 136.A NZ GLU 132.A OE2 no hydrogen 3.211 N/A ALA 137.A N SER 133.A O no hydrogen 2.953 N/A LYS 138.A N LEU 134.A O no hydrogen 2.950 N/A LYS 138.A NZ THR 117.A OG1 no hydrogen 2.851 N/A LYS 139.A N LEU 135.A O no hydrogen 2.949 N/A GLU 140.A N LYS 136.A O no hydrogen 2.973 N/A ILE 141.A N ALA 137.A O no hydrogen 2.959 N/A ASP 142.A N LYS 138.A O no hydrogen 2.926 N/A ALA 143.A N LYS 139.A O no hydrogen 2.929 N/A CYS 144.A N GLU 140.A O no hydrogen 3.000 N/A CYS 144.A SG GLU 140.A O no hydrogen 3.525 N/A LEU 145.A N ILE 141.A O no hydrogen 2.912 N/A ASN 146.A N ASP 142.A O no hydrogen 2.912 N/A GLU 147.A N ALA 143.A O no hydrogen 2.993 N/A LEU 148.A N CYS 144.A O no hydrogen 2.920 N/A ASP 149.A N LEU 145.A O no hydrogen 2.971 N/A GLY 150.A N GLU 147.A O no hydrogen 3.227 N/A VAL 151.A N LEU 148.A O no hydrogen 3.343 N/A VAL 158.A N ILE 155.A O no hydrogen 3.203 N/A ARG 159.A NE PHE 234.A O no hydrogen 3.386 N/A ARG 159.A NE LEU 235.A O no hydrogen 2.883 N/A ARG 159.A NH1 ASP 156.A OD1 no hydrogen 2.719 N/A ARG 159.A NH2 TYR 94.A OH no hydrogen 2.972 N/A ARG 159.A NH2 ASP 156.A OD1 no hydrogen 3.435 N/A ARG 159.A NH2 PHE 234.A O no hydrogen 2.799 N/A LEU 162.A N VAL 158.A O no hydrogen 3.158 N/A LEU 163.A N ARG 159.A O no hydrogen 2.907 N/A GLY 164.A N GLU 160.A O no hydrogen 2.909 N/A ILE 165.A N ARG 161.A O no hydrogen 2.995 N/A GLU 166.A N LEU 162.A O no hydrogen 2.913 N/A GLY 167.A N LEU 163.A O no hydrogen 2.915 N/A LYS 168.A N GLY 164.A O no hydrogen 2.988 N/A ALA 169.A N ILE 165.A O no hydrogen 3.012 N/A SER 170.A N GLU 166.A O no hydrogen 2.897 N/A SER 170.A OG GLU 166.A O no hydrogen 3.122 N/A LYS 171.A N GLY 167.A O no hydrogen 2.962 N/A LYS 171.A NZ ASP 175.A OD2 no hydrogen 3.419 N/A HIS 172.A N LYS 168.A O no hydrogen 3.041 N/A TYR 173.A N ALA 169.A O no hydrogen 2.927 N/A TYR 173.A OH ASP 258.A OD2 no hydrogen 2.720 N/A TRP 174.A N SER 170.A O no hydrogen 2.903 N/A ASP 175.A N LYS 171.A O no hydrogen 2.994 N/A ALA 176.A N HIS 172.A O no hydrogen 3.030 N/A ILE 177.A N TYR 173.A O no hydrogen 2.888 N/A SER 178.A N TRP 174.A O no hydrogen 2.919 N/A SER 178.A OG ASP 175.A O no hydrogen 2.423 N/A LEU 179.A N ASP 175.A O no hydrogen 3.079 N/A LEU 179.A N ALA 176.A O no hydrogen 3.144 N/A VAL 180.A N ILE 177.A O no hydrogen 2.895 N/A ILE 181.A N ILE 177.A O no hydrogen 3.300 N/A GLU 184.A N GLU 184.A OE1 no hydrogen 2.716 N/A TYR 185.A N PRO 182.A O no hydrogen 3.158 N/A TYR 185.A OH ILE 270.A O no hydrogen 2.502 N/A ARG 186.A N GLU 183.A O no hydrogen 3.143 N/A ARG 186.A NE ARG 186.A O no hydrogen 2.625 N/A ARG 186.A NH2 ASP 203.A OD1 no hydrogen 3.401 N/A ARG 190.A NH1 ASN 206.A OD1 no hydrogen 3.005 N/A ARG 190.A NH1 ASN 209.A OD1 no hydrogen 3.006 N/A ARG 190.A NH2 ASN 209.A OD1 no hydrogen 2.584 N/A ARG 191.A N ASN 206.A OD1 no hydrogen 3.143 N/A ARG 191.A NE ARG 199.A O no hydrogen 3.597 N/A ASN 206.A N ASP 203.A OD2 no hydrogen 3.145 N/A ASN 206.A ND2 GLY 189.A O no hydrogen 3.156 N/A ASN 206.A ND2 ASP 203.A OD1 no hydrogen 3.013 N/A ASN 206.A ND2 ASP 203.A OD2 no hydrogen 3.040 N/A ALA 207.A N ASP 203.A O no hydrogen 3.154 N/A ASN 209.A N ASN 206.A O no hydrogen 2.903 N/A TYR 210.A N ALA 207.A O no hydrogen 2.999 N/A TYR 212.A N LEU 208.A O no hydrogen 2.880 N/A TYR 212.A OH ASP 258.A OD1 no hydrogen 2.607 N/A SER 213.A N ASN 209.A O no hydrogen 2.984 N/A SER 213.A OG GLU 71.A OE2 no hydrogen 3.037 N/A SER 213.A OG ASN 209.A O no hydrogen 2.993 N/A ILE 214.A N TYR 210.A O no hydrogen 3.010 N/A LEU 215.A N GLY 211.A O no hydrogen 2.921 N/A LEU 216.A N TYR 212.A O no hydrogen 2.897 N/A ALA 217.A N SER 213.A O no hydrogen 2.971 N/A GLU 218.A N ILE 214.A O no hydrogen 3.012 N/A CYS 219.A N LEU 215.A O no hydrogen 2.897 N/A CYS 219.A SG LEU 215.A O no hydrogen 3.371 N/A VAL 220.A N LEU 216.A O no hydrogen 2.900 N/A LYS 221.A N ALA 217.A O no hydrogen 2.997 N/A ALA 222.A N GLU 218.A O no hydrogen 2.939 N/A VAL 223.A N CYS 219.A O no hydrogen 2.910 N/A GLU 224.A N VAL 220.A O no hydrogen 2.919 N/A LEU 225.A N LYS 221.A O no hydrogen 2.947 N/A ALA 226.A N ALA 222.A O no hydrogen 3.266 N/A GLY 227.A N GLU 224.A O no hydrogen 3.152 N/A LEU 228.A N VAL 223.A O no hydrogen 3.176 N/A ASP 229.A N GLN 90.A OE1 no hydrogen 2.827 N/A TYR 231.A N ASP 229.A OD1 no hydrogen 3.244 N/A ALA 232.A N ASP 229.A O no hydrogen 3.344 N/A PHE 234.A N ASP 248.A OD2 no hydrogen 2.861 N/A LEU 235.A N ASP 248.A OD2 no hydrogen 2.529 N/A HIS 236.A N ASP 248.A OD1 no hydrogen 2.968 N/A HIS 236.A NE2 GLU 250.A OE1 no hydrogen 3.046 N/A VAL 237.A N LEU 235.A O no hydrogen 3.077 N/A SER 244.A OG TYR 231.A O no hydrogen 3.103 N/A SER 244.A OG ARG 242.A O no hydrogen 3.110 N/A LEU 245.A N PRO 230.A O no hydrogen 2.790 N/A ILE 247.A N SER 243.A O no hydrogen 3.039 N/A ASP 248.A N SER 244.A O no hydrogen 2.914 N/A LEU 249.A N LEU 245.A O no hydrogen 2.898 N/A ASN 251.A N LEU 249.A O no hydrogen 3.180 N/A ASN 251.A ND2 LEU 249.A O no hydrogen 3.310 N/A ASN 251.A ND2 TYR 333.A OH no hydrogen 2.830 N/A GLN 254.A NE2 ASP 258.A OD2 no hydrogen 2.785 N/A VAL 256.A N PHE 252.A O no hydrogen 2.961 N/A VAL 257.A N ARG 253.A O no hydrogen 2.928 N/A ASP 258.A N ARG 253.A O no hydrogen 2.995 N/A ARG 259.A N GLN 254.A O no hydrogen 3.085 N/A VAL 261.A N VAL 257.A O no hydrogen 2.963 N/A LEU 262.A N ASP 258.A O no hydrogen 2.866 N/A ARG 263.A N ARG 259.A O no hydrogen 2.930 N/A LEU 264.A N VAL 260.A O no hydrogen 2.932 N/A ILE 265.A N VAL 261.A O no hydrogen 2.951 N/A SER 266.A N LEU 262.A O no hydrogen 2.927 N/A SER 266.A OG ARG 263.A O no hydrogen 2.644 N/A TYR 267.A N ARG 263.A O no hydrogen 3.309 N/A ARG 268.A N ILE 265.A O no hydrogen 3.041 N/A ARG 268.A NH1 ILE 265.A O no hydrogen 2.855 N/A GLN 269.A N LEU 264.A O no hydrogen 3.009 N/A LYS 271.A N ASP 274.A OD2 no hydrogen 2.751 N/A LYS 271.A NZ ARG 268.A O no hydrogen 2.565 N/A GLU 273.A N GLU 273.A OE1 no hydrogen 2.738 N/A ASP 274.A N LYS 271.A O no hydrogen 2.900 N/A CYS 275.A N PRO 272.A O no hydrogen 3.348 N/A GLU 276.A N GLN 282.A O no hydrogen 2.847 N/A ARG 278.A N GLU 276.A O no hydrogen 2.835 N/A CYS 281.A N ALA 201.A O no hydrogen 2.746 N/A GLN 282.A N GLU 276.A O no hydrogen 2.916 N/A SER 284.A N ASP 274.A O no hydrogen 3.115 N/A SER 284.A OG ASP 274.A OD1 no hydrogen 3.510 N/A ALA 287.A N SER 284.A OG no hydrogen 3.260 N/A ARG 288.A N SER 284.A O no hydrogen 2.775 N/A ARG 289.A N ASP 285.A O no hydrogen 2.923 N/A ARG 289.A NH1 ASN 286.A OD1 no hydrogen 2.852 N/A LEU 290.A N ASN 286.A O no hydrogen 2.935 N/A LEU 291.A N ALA 287.A O no hydrogen 2.919 N/A LEU 292.A N ARG 288.A O no hydrogen 2.910 N/A ALA 293.A N ARG 289.A O no hydrogen 2.945 N/A SER 294.A N LEU 290.A O no hydrogen 2.921 N/A SER 294.A OG LEU 290.A O no hydrogen 2.717 N/A LEU 295.A N LEU 291.A O no hydrogen 2.910 N/A LEU 296.A N LEU 292.A O no hydrogen 2.928 N/A GLU 297.A N ALA 293.A O no hydrogen 2.941 N/A ARG 298.A N SER 294.A O no hydrogen 2.918 N/A ARG 298.A NE GLN 255.A O no hydrogen 2.920 N/A ARG 298.A NH2 GLN 255.A O no hydrogen 2.891 N/A LEU 299.A N LEU 295.A O no hydrogen 2.902 N/A ASP 300.A N LEU 296.A O no hydrogen 2.963 N/A SER 301.A N ARG 298.A O no hydrogen 3.270 N/A SER 301.A OG ARG 298.A O no hydrogen 2.755 N/A THR 303.A N LEU 310.A O no hydrogen 2.866 N/A THR 303.A OG1 GLN 338.A OE1 no hydrogen 2.754 N/A GLN 304.A NE2 ASN 309.A OD1 no hydrogen 3.363 N/A TYR 305.A N ARG 308.A O no hydrogen 2.889 N/A TYR 305.A OH HIS 319.A NE2 no hydrogen 2.814 N/A ARG 306.A NH1 ASP 322.A OD1 no hydrogen 3.444 N/A ARG 306.A NH2 ASP 322.A OD2 no hydrogen 2.353 N/A ARG 308.A N TYR 305.A O no hydrogen 3.115 N/A LEU 310.A N THR 303.A O no hydrogen 2.902 N/A TYR 312.A N SER 301.A O no hydrogen 3.290 N/A SER 313.A N LEU 299.A O no hydrogen 3.015 N/A SER 313.A OG LEU 299.A O no hydrogen 3.288 N/A SER 313.A OG ASP 300.A OD1 no hydrogen 3.498 N/A ILE 315.A N ALA 311.A O no hydrogen 3.021 N/A ILE 316.A N TYR 312.A O no hydrogen 2.896 N/A LEU 317.A N SER 313.A O no hydrogen 2.981 N/A LEU 318.A N SER 314.A O no hydrogen 2.859 N/A HIS 319.A N ILE 315.A O no hydrogen 2.914 N/A HIS 319.A ND1 TYR 333.A OH no hydrogen 2.770 N/A HIS 319.A NE2 TYR 305.A OH no hydrogen 2.814 N/A ALA 320.A N ILE 316.A O no hydrogen 3.001 N/A ARG 321.A N LEU 317.A O no hydrogen 2.965 N/A ASP 322.A N LEU 318.A O no hydrogen 2.855 N/A VAL 323.A N HIS 319.A O no hydrogen 2.929 N/A VAL 324.A N ALA 320.A O no hydrogen 3.028 N/A ALA 325.A N ARG 321.A O no hydrogen 2.885 N/A PHE 326.A N ASP 322.A O no hydrogen 2.895 N/A LEU 327.A N VAL 323.A O no hydrogen 2.966 N/A ARG 328.A N VAL 324.A O no hydrogen 3.098 N/A ARG 328.A NH2 THR 86.A OG1 no hydrogen 2.880 N/A GLY 329.A N PHE 326.A O no hydrogen 3.028 N/A GLU 330.A N ALA 325.A O no hydrogen 2.831 N/A ARG 331.A N ALA 325.A O no hydrogen 3.255 N/A TYR 333.A OH HIS 319.A ND1 no hydrogen 2.770 N/A GLY 335.A N GLU 105.A OE1 no hydrogen 3.035 N/A PHE 336.A N ASN 251.A OD1 no hydrogen 2.815 N/A LYS 339.A NZ ASN 118.A OD1 no hydrogen 3.125 N/A LYS 339.A NZ GLN 255.A OE1 no hydrogen 3.145 N/A