Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4n0n_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): CYS 4.A N ALA 9.A O no hydrogen 2.795 N/A CYS 4.A SG TRP 20.A O no hydrogen 3.738 N/A THR 5.A N TRP 20.A O no hydrogen 2.583 N/A THR 5.A OG1 TRP 20.A O no hydrogen 3.131 N/A GLY 8.A N CYS 4.A O no hydrogen 2.972 N/A VAL 12.A N PHE 21.A O no hydrogen 2.679 N/A ALA 13.A N PHE 21.A O no hydrogen 3.149 N/A LYS 14.A N THR 36.A O no hydrogen 2.913 N/A SER 15.A N GLY 19.A O no hydrogen 3.052 N/A SER 15.A OG GLY 19.A O no hydrogen 3.489 N/A ALA 16.A N HIS 34.A O no hydrogen 2.912 N/A CYS 17.A SG SER 15.A OG no hydrogen 3.122 N/A CYS 17.A SG HIS 29.A NE2 no hydrogen 3.514 N/A CYS 17.A SG HIS 32.A ND1 no hydrogen 3.673 N/A GLY 18.A N SER 15.A O no hydrogen 3.132 N/A GLY 19.A N SER 15.A OG no hydrogen 2.994 N/A TRP 20.A N THR 5.A OG1 no hydrogen 2.790 N/A PHE 21.A N ALA 13.A O no hydrogen 3.056 N/A CYS 25.A N CYS 22.A O no hydrogen 3.069 N/A VAL 26.A N CYS 22.A O no hydrogen 2.984 N/A TYR 28.A N CYS 25.A O no hydrogen 2.928 N/A HIS 29.A N VAL 26.A O no hydrogen 3.082 N/A HIS 32.A N HIS 29.A O no hydrogen 3.004 N/A HIS 32.A NE2 ASP 80.A OD1 no hydrogen 2.817 N/A CYS 33.A SG HIS 29.A NE2 no hydrogen 3.523 N/A CYS 33.A SG HIS 32.A ND1 no hydrogen 3.474 N/A CYS 33.A SG HIS 34.A O no hydrogen 4.017 N/A THR 35.A N ASP 45.A OD2 no hydrogen 3.184 N/A THR 35.A OG1 CYS 33.A O no hydrogen 2.857 N/A THR 36.A N LYS 14.A O no hydrogen 2.928 N/A LEU 38.A N VAL 12.A O no hydrogen 2.702 N/A PHE 39.A N SER 37.A OG no hydrogen 2.980 N/A CYS 42.A SG HIS 44.A ND1 no hydrogen 3.260 N/A ILE 46.A N THR 35.A O no hydrogen 2.776 N/A MET 47.A N ASP 45.A OD1 no hydrogen 2.844 N/A TYR 48.A N ASP 45.A O no hydrogen 3.130 N/A ARG 49.A N ILE 46.A O no hydrogen 2.920 N/A SER 50.A N TYR 52.A O no hydrogen 2.985 N/A CYS 53.A SG HIS 44.A ND1 no hydrogen 3.420 N/A THR 54.A N TYR 48.A O no hydrogen 2.803 N/A THR 54.A OG1 TYR 48.A O no hydrogen 2.682 N/A THR 54.A OG1 LYS 61.A O no hydrogen 3.164 N/A CYS 56.A SG HIS 44.A ND1 no hydrogen 3.544 N/A GLU 57.A N CYS 53.A O no hydrogen 3.212 N/A GLY 58.A N MET 55.A O no hydrogen 3.207 N/A LYS 61.A N THR 54.A OG1 no hydrogen 3.137 N/A GLN 62.A NE2 VAL 64.A O no hydrogen 2.777 N/A MET 63.A N MET 47.A O no hydrogen 2.751 N/A VAL 64.A N MET 47.A O no hydrogen 3.095 N/A LYS 66.A NZ TYR 28.A O no hydrogen 2.926 N/A LYS 66.A NZ VAL 67.A O no hydrogen 2.893 N/A LYS 66.A NZ ASP 73.A OD1 no hydrogen 2.732 N/A LYS 66.A NZ ASP 73.A OD2 no hydrogen 3.545 N/A VAL 67.A N PRO 27.A O no hydrogen 2.801 N/A HIS 69.A N ASP 73.A OD2 no hydrogen 2.912 N/A ASP 73.A N HIS 69.A O no hydrogen 3.046 N/A LEU 75.A N ILE 71.A O no hydrogen 3.055 N/A LEU 76.A N LEU 72.A O no hydrogen 2.822 N/A CYS 77.A N ASP 73.A O no hydrogen 2.960 N/A CYS 77.A SG SER 275.A OG no hydrogen 3.427 N/A HIS 78.A N HIS 74.A O no hydrogen 2.968 N/A ILE 79.A N LEU 75.A O no hydrogen 2.929 N/A ASP 80.A N LEU 76.A O no hydrogen 2.825 N/A TYR 81.A N HIS 78.A O no hydrogen 3.079 N/A LEU 87.A N ALA 131.A O no hydrogen 3.040 N/A LEU 89.A N HIS 129.A O no hydrogen 2.714 N/A VAL 91.A N GLY 127.A O no hydrogen 2.795 N/A ALA 92.A N ARG 95.A O no hydrogen 2.982 N/A ARG 95.A N ALA 92.A O no hydrogen 2.992 N/A ARG 95.A NH1 ASP 115.A OD2 no hydrogen 2.717 N/A ARG 95.A NH1 GLY 118.A O no hydrogen 2.817 N/A THR 96.A N ASN 119.A O no hydrogen 2.747 N/A THR 96.A OG1 VAL 90.A O no hydrogen 2.811 N/A THR 96.A OG1 SER 98.A OG no hydrogen 3.372 N/A SER 98.A N THR 96.A OG1 no hydrogen 3.034 N/A SER 98.A OG THR 96.A OG1 no hydrogen 3.372 N/A GLY 101.A N VAL 112.A O no hydrogen 2.794 N/A TYR 103.A N VAL 110.A O no hydrogen 2.735 N/A TYR 103.A OH PRO 99.A O no hydrogen 2.575 N/A LYS 104.A N VAL 132.A O no hydrogen 2.777 N/A VAL 105.A N LYS 108.A O no hydrogen 3.061 N/A LYS 108.A N VAL 105.A O no hydrogen 3.246 N/A LYS 108.A NZ VAL 105.A O no hydrogen 3.166 N/A VAL 110.A N TYR 103.A O no hydrogen 2.733 N/A ALA 111.A N PHE 122.A O no hydrogen 3.067 N/A VAL 112.A N GLY 101.A O no hydrogen 2.815 N/A VAL 113.A N ILE 120.A O no hydrogen 2.843 N/A ASP 115.A N ASN 119.A OD1 no hydrogen 3.272 N/A GLY 117.A N ASP 115.A OD2 no hydrogen 2.950 N/A GLY 118.A N ASP 115.A O no hydrogen 2.939 N/A ASN 119.A ND2 SER 98.A O no hydrogen 2.701 N/A ILE 120.A N VAL 113.A O no hydrogen 2.900 N/A VAL 121.A N GLY 94.A O no hydrogen 2.876 N/A PHE 122.A N ALA 111.A O no hydrogen 2.824 N/A CYS 124.A SG GLY 125.A O no hydrogen 3.910 N/A GLY 127.A N VAL 91.A O no hydrogen 2.892 N/A HIS 129.A N LEU 89.A O no hydrogen 2.859 N/A HIS 129.A NE2 GLY 125.A O no hydrogen 2.848 N/A ALA 131.A N LEU 87.A O no hydrogen 3.012 N/A VAL 132.A N LYS 104.A O no hydrogen 2.963 N/A LEU 134.A N ARG 102.A O no hydrogen 2.725 N/A GLN 135.A NE2 ILE 79.A O no hydrogen 3.463 N/A THR 137.A N ASP 136.A OD1 no hydrogen 2.852 N/A LEU 138.A N CYS 17.A O no hydrogen 2.892 N/A LYS 139.A N THR 137.A OG1 no hydrogen 3.170 N/A VAL 141.A N LEU 138.A O no hydrogen 3.113 N/A VAL 142.A N THR 255.A OG1 no hydrogen 2.970 N/A VAL 143.A N THR 5.A O no hydrogen 2.794 N/A ASN 144.A N VAL 6.A O no hydrogen 2.909 N/A ALA 146.A N VAL 142.A O no hydrogen 2.918 N/A LEU 147.A N VAL 143.A O no hydrogen 2.917 N/A LYS 148.A N ASN 144.A O no hydrogen 3.192 N/A ASN 149.A N LYS 145.A O no hydrogen 3.003 N/A ASN 149.A ND2 LEU 254.A O no hydrogen 2.703 N/A ALA 150.A N ALA 146.A O no hydrogen 2.798 N/A ALA 151.A N LEU 147.A O no hydrogen 3.155 N/A ALA 152.A N ASN 149.A O no hydrogen 3.171 N/A SER 153.A N ALA 150.A O no hydrogen 2.994 N/A SER 153.A OG ASN 149.A O no hydrogen 2.648 N/A GLU 154.A N VAL 259.A O no hydrogen 2.899 N/A TYR 155.A N VAL 286.A O no hydrogen 2.868 N/A VAL 156.A N GLY 261.A O no hydrogen 2.808 N/A GLY 158.A N GLY 263.A O no hydrogen 2.838 N/A SER 162.A N PRO 159.A O no hydrogen 3.191 N/A SER 162.A OG PRO 159.A O no hydrogen 2.686 N/A LYS 164.A NZ GLY 158.A O no hydrogen 2.717 N/A LYS 164.A NZ PRO 159.A O no hydrogen 3.168 N/A THR 165.A OG1 ASP 240.A OD1 no hydrogen 2.862 N/A HIS 167.A N GLY 163.A O no hydrogen 2.966 N/A LEU 168.A N LYS 164.A O no hydrogen 2.905 N/A VAL 169.A N THR 165.A O no hydrogen 2.947 N/A LYS 170.A N PHE 166.A O no hydrogen 3.183 N/A ASP 171.A N HIS 167.A O no hydrogen 3.108 N/A VAL 172.A N LEU 168.A O no hydrogen 3.019 N/A LEU 173.A N VAL 169.A O no hydrogen 3.015 N/A ALA 174.A N LYS 170.A O no hydrogen 3.145 N/A ALA 174.A N ASP 171.A O no hydrogen 3.220 N/A VAL 175.A N VAL 172.A O no hydrogen 3.278 N/A ALA 179.A N ASN 222.A O no hydrogen 3.152 N/A THR 180.A N GLU 236.A O no hydrogen 2.836 N/A THR 180.A OG1 GLU 234.A O no hydrogen 2.733 N/A LEU 181.A N THR 224.A O no hydrogen 2.700 N/A VAL 182.A N PHE 238.A O no hydrogen 2.805 N/A VAL 183.A N ARG 226.A O no hydrogen 2.945 N/A SER 188.A N THR 185.A OG1 no hydrogen 3.026 N/A SER 188.A OG ASP 240.A OD2 no hydrogen 2.455 N/A MET 189.A N THR 185.A O no hydrogen 2.896 N/A LEU 190.A N HIS 186.A O no hydrogen 2.913 N/A ASP 191.A N ALA 187.A O no hydrogen 2.887 N/A CYS 192.A N SER 188.A O no hydrogen 2.862 N/A CYS 192.A SG SER 188.A O no hydrogen 3.409 N/A ILE 193.A N MET 189.A O no hydrogen 2.886 N/A ASN 194.A N LEU 190.A O no hydrogen 2.859 N/A LYS 195.A N ASP 191.A O no hydrogen 3.035 N/A LYS 195.A NZ ASP 191.A OD1 no hydrogen 2.915 N/A LEU 196.A N CYS 192.A O no hydrogen 3.053 N/A LYS 197.A N ILE 193.A O no hydrogen 2.949 N/A GLN 198.A N ASN 194.A O no hydrogen 2.904 N/A ALA 199.A N LYS 195.A O no hydrogen 3.155 N/A GLY 200.A N LYS 197.A O no hydrogen 3.099 N/A ALA 201.A N LEU 196.A O no hydrogen 2.990 N/A TYR 204.A N ILE 223.A O no hydrogen 2.841 N/A LEU 213.A N THR 211.A OG1 no hydrogen 3.150 N/A GLY 219.A N PRO 203.A O no hydrogen 3.050 N/A SER 220.A N ASP 202.A OD2 no hydrogen 3.286 N/A GLY 221.A N ASP 202.A O no hydrogen 2.900 N/A THR 224.A N ALA 179.A O no hydrogen 2.967 N/A VAL 225.A N TYR 204.A O no hydrogen 3.007 N/A ARG 226.A N LEU 181.A O no hydrogen 2.872 N/A ARG 226.A NE SER 233.A OG no hydrogen 3.420 N/A ARG 226.A NH1 PRO 228.A O no hydrogen 3.268 N/A ARG 226.A NH1 VAL 230.A O no hydrogen 3.051 N/A ARG 226.A NH2 SER 233.A OG no hydrogen 2.872 N/A VAL 230.A N LEU 227.A O no hydrogen 3.100 N/A SER 233.A N GLN 256.A OE1 no hydrogen 2.911 N/A GLU 234.A N THR 180.A OG1 no hydrogen 2.843 N/A THR 237.A OG1 GLY 235.A O no hydrogen 2.900 N/A PHE 238.A N THR 180.A O no hydrogen 2.814 N/A VAL 239.A N LYS 260.A O no hydrogen 2.969 N/A ASP 240.A N VAL 182.A O no hydrogen 2.917 N/A VAL 242.A N TYR 262.A O no hydrogen 2.793 N/A TYR 244.A N GLU 241.A O no hydrogen 2.974 N/A ASP 249.A N SER 246.A OG no hydrogen 3.108 N/A LEU 250.A N SER 246.A O no hydrogen 3.011 N/A ALA 251.A N PRO 247.A O no hydrogen 2.998 N/A ARG 252.A N VAL 248.A O no hydrogen 2.977 N/A ARG 252.A NE ASP 249.A OD1 no hydrogen 3.004 N/A ARG 252.A NH1 THR 137.A O no hydrogen 2.791 N/A ARG 252.A NH1 LYS 139.A O no hydrogen 3.018 N/A ARG 252.A NH2 ASP 136.A OD1 no hydrogen 2.877 N/A ARG 252.A NH2 ASP 249.A OD1 no hydrogen 2.994 N/A ILE 253.A N ASP 249.A O no hydrogen 2.925 N/A LEU 254.A N LEU 250.A O no hydrogen 2.937 N/A THR 255.A N ALA 251.A O no hydrogen 2.900 N/A THR 255.A OG1 GLY 140.A O no hydrogen 3.563 N/A THR 255.A OG1 VAL 142.A O no hydrogen 3.502 N/A THR 255.A OG1 ALA 251.A O no hydrogen 2.696 N/A GLN 256.A N ILE 253.A O no hydrogen 3.082 N/A VAL 259.A N SER 153.A OG no hydrogen 3.013 N/A LYS 260.A N THR 237.A O no hydrogen 3.010 N/A LYS 260.A NZ ASP 171.A OD2 no hydrogen 2.731 N/A GLY 261.A N GLU 154.A O no hydrogen 2.761 N/A TYR 262.A N VAL 239.A O no hydrogen 3.043 N/A TYR 262.A OH ASP 171.A OD2 no hydrogen 2.485 N/A GLY 263.A N VAL 156.A O no hydrogen 3.061 N/A LEU 265.A N TYR 155.A OH no hydrogen 3.323 N/A ASN 266.A N ASP 264.A OD1 no hydrogen 2.832 N/A GLN 267.A N ASP 264.A O no hydrogen 3.263 N/A GLN 267.A NE2 ASP 264.A OD2 no hydrogen 2.976 N/A CYS 270.A N TYR 244.A O no hydrogen 2.837 N/A CYS 270.A SG VAL 271.A O no hydrogen 3.545 N/A VAL 276.A N PRO 273.A O no hydrogen 3.300 N/A ARG 278.A NH1 GLN 267.A O no hydrogen 2.807 N/A ARG 278.A NH2 ALA 243.A O no hydrogen 2.880 N/A ARG 278.A NH2 GLN 267.A O no hydrogen 3.027 N/A LEU 280.A N PRO 277.A O no hydrogen 3.052 N/A TRP 281.A NE1 PRO 247.A O no hydrogen 2.915 N/A ARG 283.A N ASN 279.A O no hydrogen 2.885 N/A ARG 283.A NE ASN 279.A O no hydrogen 3.351 N/A ARG 283.A NE ASN 279.A OD1 no hydrogen 3.339 N/A ARG 283.A NH2 ASN 279.A OD1 no hydrogen 2.814 N/A HIS 284.A N TRP 281.A O no hydrogen 2.997 N/A PHE 285.A N LEU 282.A O no hydrogen 3.147 N/A VAL 286.A N SER 153.A O no hydrogen 2.809 N/A LEU 288.A N TYR 155.A O no hydrogen 2.884 N/A LEU 291.A N GLU 157.A O no hydrogen 2.826 N/A CYS 294.A N GLU 313.A O no hydrogen 2.808 N/A CYS 294.A SG GLY 161.A O no hydrogen 3.790 N/A CYS 294.A SG PHE 297.A O no hydrogen 3.720 N/A CYS 294.A SG TYR 312.A OH no hydrogen 3.299 N/A HIS 295.A N GLY 161.A O no hydrogen 2.779 N/A GLY 298.A N THR 319.A OG1 no hydrogen 2.961 N/A VAL 301.A N GLY 298.A O no hydrogen 3.274 N/A CYS 302.A N GLY 298.A O no hydrogen 3.326 N/A CYS 302.A SG GLY 298.A O no hydrogen 3.785 N/A ASP 303.A N ALA 299.A O no hydrogen 2.738 N/A LEU 304.A N ALA 300.A O no hydrogen 3.381 N/A ILE 305.A N VAL 301.A O no hydrogen 3.103 N/A LYS 306.A N ASP 303.A O no hydrogen 3.153 N/A ILE 308.A N ILE 305.A O no hydrogen 3.032 N/A TYR 309.A N ILE 305.A O no hydrogen 2.968 N/A TYR 309.A OH ASP 264.A OD2 no hydrogen 2.482 N/A TYR 311.A OH GLU 157.A OE1 no hydrogen 2.638 N/A TYR 312.A OH PRO 160.A O no hydrogen 2.758 N/A GLU 313.A N ARG 292.A O no hydrogen 2.811 N/A ALA 315.A N PHE 297.A O no hydrogen 2.930 N/A HIS 317.A NE2 ARG 296.A O no hydrogen 2.903 N/A HIS 317.A NE2 SER 383.A O no hydrogen 3.119 N/A THR 319.A OG1 SER 383.A O no hydrogen 2.701 N/A LYS 320.A N GLN 384.A O no hydrogen 2.969 N/A VAL 322.A N LEU 386.A O no hydrogen 2.962 N/A VAL 324.A N ILE 388.A O no hydrogen 2.665 N/A ASP 328.A N ASN 326.A OD1 no hydrogen 2.900 N/A PHE 329.A N ASN 326.A O no hydrogen 3.089 N/A LYS 331.A N THR 361.A OG1 no hydrogen 2.861 N/A VAL 333.A N VAL 359.A O no hydrogen 2.954 N/A ILE 335.A N THR 361.A O no hydrogen 2.809 N/A THR 336.A N ARG 347.A O no hydrogen 2.837 N/A THR 336.A OG1 ARG 363.A O no hydrogen 2.650 N/A TYR 338.A OH GLN 368.A O no hydrogen 3.230 N/A ASP 341.A N TYR 338.A O no hydrogen 3.061 N/A ARG 342.A N HIS 339.A O no hydrogen 3.104 N/A ARG 342.A NE HIS 339.A O no hydrogen 3.228 N/A GLY 343.A N HIS 346.A ND1 no hydrogen 2.931 N/A HIS 346.A N GLY 343.A O no hydrogen 3.004 N/A HIS 346.A NE2 GLU 330.A OE1 no hydrogen 3.121 N/A ARG 347.A N VAL 334.A O no hydrogen 2.748 N/A ARG 347.A NH2 SER 351.A OG no hydrogen 3.320 N/A ILE 349.A N THR 336.A O no hydrogen 2.898 N/A SER 351.A OG THR 348.A O no hydrogen 3.032 N/A ILE 352.A N THR 348.A O no hydrogen 3.366 N/A ILE 352.A N ILE 349.A O no hydrogen 3.155 N/A GLN 353.A N ASP 350.A O no hydrogen 3.422 N/A GLN 353.A NE2 ASP 350.A O no hydrogen 3.140 N/A CYS 355.A N ILE 352.A O no hydrogen 2.960 N/A PHE 357.A N ARG 381.A O no hydrogen 2.812 N/A VAL 360.A N GLU 385.A O no hydrogen 3.055 N/A THR 361.A N VAL 333.A O no hydrogen 2.881 N/A THR 361.A OG1 LYS 331.A O no hydrogen 2.727 N/A LEU 362.A N TYR 387.A O no hydrogen 2.832 N/A ARG 363.A N ILE 335.A O no hydrogen 2.831 N/A LEU 364.A N TYR 389.A O no hydrogen 2.793 N/A THR 366.A OG1 ASP 341.A OD1 no hydrogen 3.249 N/A THR 366.A OG1 ASP 341.A OD2 no hydrogen 2.535 N/A SER 369.A N GLN 394.A OE1 no hydrogen 3.078 N/A SER 369.A OG THR 366.A O no hydrogen 3.092 N/A SER 369.A OG GLN 394.A OE1 no hydrogen 2.793 N/A ARG 374.A N THR 371.A OG1 no hydrogen 3.302 N/A ARG 374.A NE ASP 350.A OD1 no hydrogen 3.196 N/A ARG 374.A NH1 SER 369.A O no hydrogen 2.878 N/A ALA 375.A N THR 371.A O no hydrogen 2.948 N/A VAL 376.A N ARG 372.A O no hydrogen 2.950 N/A VAL 377.A N PRO 373.A O no hydrogen 3.198 N/A ALA 378.A N ARG 374.A O no hydrogen 2.971 N/A VAL 379.A N ALA 375.A O no hydrogen 3.269 N/A THR 380.A N VAL 377.A O no hydrogen 3.168 N/A ARG 381.A NE VAL 377.A O no hydrogen 2.832 N/A ARG 381.A NH1 CYS 355.A O no hydrogen 2.926 N/A SER 383.A N PHE 357.A O no hydrogen 2.853 N/A SER 383.A OG PHE 357.A O no hydrogen 3.453 N/A GLN 384.A N PRO 358.A O no hydrogen 2.872 N/A GLU 385.A N PRO 358.A O no hydrogen 2.946 N/A LEU 386.A N LYS 320.A O no hydrogen 2.727 N/A TYR 387.A N VAL 360.A O no hydrogen 2.984 N/A TYR 387.A OH GLU 385.A OE1 no hydrogen 2.687 N/A ILE 388.A N VAL 322.A O no hydrogen 2.815 N/A TYR 389.A N LEU 362.A O no hydrogen 2.870 N/A ASP 393.A N ASP 390.A O no hydrogen 3.142 N/A GLN 394.A N ASP 390.A OD1 no hydrogen 2.866 N/A GLN 394.A NE2 THR 366.A O no hydrogen 2.805 N/A LEU 395.A N ASP 390.A OD2 no hydrogen 2.981 N/A SER 396.A OG ASP 393.A O no hydrogen 3.493 N/A SER 396.A OG ASP 393.A OD1 no hydrogen 2.876 N/A LEU 398.A N LEU 395.A O no hydrogen 3.185 N/A LEU 399.A N LEU 395.A O no hydrogen 2.823 N/A