Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4ne4_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLN 2.A N GLN 2.A OE1.B no hydrogen 2.931 N/A VAL 3.A N GLU 30.A O no hydrogen 2.909 N/A VAL 4.A N ASP 53.A OD2 no hydrogen 2.850 N/A VAL 5.A N THR 32.A O no hydrogen 2.898 N/A SER 6.A N ILE 54.A O no hydrogen 2.917 N/A SER 6.A OG ARG 34.A O no hydrogen 2.701 N/A SER 7.A OG LYS 8.A O no hydrogen 2.840 N/A LYS 8.A NZ THR 40.A OG1 no hydrogen 2.715 N/A LYS 8.A NZ GLU 57.A OE1 no hydrogen 3.267 N/A LYS 8.A NZ GLU 57.A OE2 no hydrogen 2.879 N/A ILE 9.A N GLY 38.A O no hydrogen 2.945 N/A GLY 13.A N ASP 10.A OD1 no hydrogen 2.937 N/A GLY 14.A N ASP 10.A O no hydrogen 3.133 N/A VAL 15.A N THR 11.A O no hydrogen 2.944 N/A LEU 16.A N GLU 12.A O no hydrogen 2.819 N/A GLY 17.A N GLY 13.A O no hydrogen 2.743 N/A ASN 18.A N GLY 14.A O no hydrogen 3.033 N/A ASN 18.A ND2 GLY 14.A O no hydrogen 2.896 N/A ILE 19.A N VAL 15.A O no hydrogen 2.943 N/A ILE 20.A N LEU 16.A O no hydrogen 2.990 N/A LEU 21.A N.A GLY 17.A O no hydrogen 2.935 N/A LEU 21.A N.B GLY 17.A O no hydrogen 2.956 N/A ALA 22.A N ASN 18.A O no hydrogen 2.928 N/A VAL 23.A N ILE 19.A O no hydrogen 2.980 N/A LEU 24.A N ILE 20.A O no hydrogen 3.021 N/A ASN 25.A N LEU 21.A O.A no hydrogen 2.924 N/A ASN 25.A N LEU 21.A O.B no hydrogen 2.938 N/A GLN 26.A N ALA 22.A O no hydrogen 2.885 N/A GLN 26.A NE2 LYS 278.A O no hydrogen 3.192 N/A ASN 27.A N VAL 23.A O no hydrogen 3.111 N/A ASN 27.A ND2 VAL 23.A O no hydrogen 2.815 N/A LYS 28.A N.A ASN 25.A O no hydrogen 3.006 N/A LYS 28.A N.B ASN 25.A O no hydrogen 3.004 N/A ILE 29.A N LEU 24.A O no hydrogen 2.939 N/A THR 31.A OG1 ASN 25.A OD1 no hydrogen 2.811 N/A THR 32.A N VAL 3.A O no hydrogen 2.933 N/A ARG 34.A N VAL 5.A O no hydrogen 2.776 N/A ARG 34.A NH1 GLU 51.A O no hydrogen 3.411 N/A ILE 35.A N ASP 33.A OD1 no hydrogen 2.962 N/A GLN 36.A N SER 7.A OG no hydrogen 2.845 N/A GLN 36.A NE2 ILE 9.A O no hydrogen 3.281 N/A GLN 36.A NE2 ASP 10.A O no hydrogen 3.098 N/A LEU 37.A N SER 7.A O no hydrogen 3.096 N/A VAL 43.A N ALA 39.A O no hydrogen 3.102 N/A ARG 44.A N THR 40.A O no hydrogen 2.856 N/A ARG 44.A NH1 ASP 88.A OD2 no hydrogen 2.915 N/A ARG 44.A NH2 ASP 88.A OD1 no hydrogen 2.873 N/A ARG 44.A NH2 ASP 88.A OD2 no hydrogen 3.552 N/A LYS 45.A N PRO 41.A O no hydrogen 2.954 N/A ALA 46.A N VAL 42.A O no hydrogen 2.968 N/A ILE 47.A N VAL 43.A O no hydrogen 2.965 N/A THR 48.A N ARG 44.A O no hydrogen 3.077 N/A THR 48.A OG1 ARG 44.A O no hydrogen 2.895 N/A THR 48.A OG1 LYS 45.A O no hydrogen 3.152 N/A ALA 49.A N LYS 45.A O no hydrogen 2.974 N/A GLY 50.A N ILE 47.A O no hydrogen 3.104 N/A GLU 51.A N ALA 46.A O no hydrogen 2.825 N/A ASP 53.A N VAL 4.A O no hydrogen 2.897 N/A ILE 54.A N VAL 4.A O no hydrogen 3.145 N/A TYR 55.A N ILE 222.A O no hydrogen 3.162 N/A TYR 55.A OH GLU 57.A OE1 no hydrogen 2.669 N/A GLU 57.A N ALA 220.A O no hydrogen 2.953 N/A TYR 58.A N GLU 57.A OE2 no hydrogen 2.833 N/A TYR 58.A OH GLU 12.A OE2 no hydrogen 2.519 N/A THR 59.A N GLN 218.A O no hydrogen 2.945 N/A THR 59.A OG1 VAL 216.A O no hydrogen 3.238 N/A ASN 61.A N TYR 58.A O no hydrogen 2.978 N/A ASN 61.A ND2 GLU 57.A OE2 no hydrogen 2.852 N/A ALA 62.A N THR 59.A O no hydrogen 3.013 N/A ALA 63.A N GLY 60.A O no hydrogen 3.114 N/A PHE 64.A N ASN 61.A O no hydrogen 3.005 N/A PHE 65.A N ASN 61.A O no hydrogen 3.278 N/A PHE 66.A N ALA 62.A O no hydrogen 3.055 N/A SER 67.A N PHE 64.A O no hydrogen 3.465 N/A LYS 68.A N ALA 63.A O no hydrogen 2.740 N/A ASP 71.A N LYS 68.A O no hydrogen 2.961 N/A LEU 73.A N ASP 71.A OD1 no hydrogen 2.918 N/A TRP 74.A NE1 LYS 68.A O no hydrogen 2.935 N/A LYS 75.A N PRO 72.A O no hydrogen 3.105 N/A ASP 76.A N LEU 73.A O no hydrogen 2.975 N/A LYS 79.A N ASP 76.A OD2 no hydrogen 2.965 N/A LYS 79.A NZ ASP 76.A OD1 no hydrogen 3.558 N/A GLY 80.A N ASP 76.A O no hydrogen 2.861 N/A TYR 81.A N ALA 77.A O no hydrogen 3.014 N/A TYR 81.A OH LEU 97.A O no hydrogen 2.661 N/A GLU 82.A N ALA 78.A O no hydrogen 3.048 N/A GLU 83.A N LYS 79.A O no hydrogen 2.947 N/A ALA 84.A N GLY 80.A O no hydrogen 2.947 N/A LYS 85.A N TYR 81.A O no hydrogen 2.936 N/A LYS 85.A NZ.A TRP 96.A O no hydrogen 2.752 N/A THR 86.A N GLU 82.A O no hydrogen 2.910 N/A THR 86.A OG1 GLU 82.A O no hydrogen 2.978 N/A LEU 87.A N GLU 83.A O no hydrogen 2.949 N/A ASP 88.A N ALA 84.A O no hydrogen 3.015 N/A TYR 89.A N LYS 85.A O no hydrogen 3.125 N/A TYR 89.A OH GLU 225.A OE2 no hydrogen 2.557 N/A ASP 90.A N THR 86.A O no hydrogen 2.916 N/A ALA 91.A N LEU 87.A O no hydrogen 2.828 N/A ASN 92.A N ASP 88.A O no hydrogen 2.978 N/A ASN 92.A ND2 ASP 88.A OD1 no hydrogen 2.837 N/A LYS 93.A N TYR 89.A O no hydrogen 2.929 N/A LYS 93.A NZ TYR 89.A O no hydrogen 3.011 N/A ILE 94.A N ASP 88.A O no hydrogen 3.067 N/A VAL 95.A N ILE 223.A O no hydrogen 2.741 N/A TRP 96.A NE1 ASP 88.A OD2 no hydrogen 2.798 N/A LEU 97.A N PRO 221.A O no hydrogen 2.895 N/A SER 100.A N PRO 219.A O no hydrogen 2.849 N/A SER 100.A OG LEU 245.A O no hydrogen 2.563 N/A ALA 102.A N SER 100.A OG no hydrogen 3.035 N/A ASN 104.A N TYR 217.A O no hydrogen 2.945 N/A ASN 104.A ND2 GLU 12.A OE2 no hydrogen 3.085 N/A THR 105.A OG1 PRO 215.A O no hydrogen 2.751 N/A ALA 107.A N VAL 192.A O no hydrogen 2.900 N/A ALA 109.A N ALA 191.A O no hydrogen 2.902 N/A LEU 110.A N VAL 205.A O no hydrogen 2.824 N/A ARG 111.A N ASN 189.A O no hydrogen 2.945 N/A ARG 111.A NE ASP 113.A OD1 no hydrogen 3.360 N/A ARG 111.A NH1 ALA 181.A O no hydrogen 3.032 N/A ARG 111.A NH1 ALA 182.A O no hydrogen 2.904 N/A ARG 111.A NH2 ASP 113.A OD2 no hydrogen 3.241 N/A LYS 112.A N GLY 203.A O no hydrogen 2.955 N/A ALA 115.A N ARG 111.A O no hydrogen 3.015 N/A ASP 116.A N LYS 112.A O no hydrogen 2.843 N/A LYS 117.A N ASP 113.A O no hydrogen 3.006 N/A ASN 118.A N VAL 114.A O no hydrogen 3.157 N/A ASN 118.A ND2 VAL 114.A O no hydrogen 2.945 N/A ASN 119.A N ASP 116.A O no hydrogen 3.320 N/A LEU 120.A N ALA 115.A O no hydrogen 2.873 N/A LYS 121.A N ASP 125.A OD2 no hydrogen 2.914 N/A THR 122.A N ASP 125.A OD2 no hydrogen 3.068 N/A LEU 123.A N GLU 208.A O no hydrogen 2.853 N/A SER 124.A N ASP 210.A OD1 no hydrogen 3.037 N/A SER 124.A OG ASP 210.A OD1 no hydrogen 3.384 N/A SER 124.A OG ASP 210.A OD2 no hydrogen 2.550 N/A ASP 125.A N THR 122.A OG1 no hydrogen 2.991 N/A PHE 126.A N THR 122.A O no hydrogen 3.017 N/A GLY 127.A N LEU 123.A O no hydrogen 2.842 N/A LYS 128.A N SER 124.A O no hydrogen 3.136 N/A TYR 129.A N ASP 125.A O no hydrogen 3.000 N/A TYR 129.A OH THR 135.A O no hydrogen 2.791 N/A VAL 130.A N PHE 126.A O no hydrogen 2.886 N/A ALA 131.A N GLY 127.A O no hydrogen 2.878 N/A GLY 132.A N LYS 128.A O no hydrogen 3.010 N/A GLY 133.A N VAL 130.A O no hydrogen 3.016 N/A GLY 134.A N TYR 129.A O no hydrogen 2.852 N/A VAL 137.A N ASN 189.A OD1 no hydrogen 3.029 N/A LEU 138.A N GLN 165.A O no hydrogen 2.828 N/A ALA 139.A N ALA 190.A O no hydrogen 2.916 N/A ALA 140.A N ILE 167.A O no hydrogen 2.889 N/A SER 142.A N LEU 169.A O no hydrogen 2.865 N/A PHE 144.A N SER 141.A OG no hydrogen 2.959 N/A VAL 145.A N SER 141.A O no hydrogen 3.010 N/A ASN 146.A N SER 142.A O no hydrogen 2.966 N/A ASN 146.A ND2 SER 142.A O no hydrogen 2.990 N/A SER 147.A N GLU 143.A O no hydrogen 2.808 N/A SER 147.A OG.A GLU 143.A O no hydrogen 2.626 N/A SER 147.A OG.B GLU 143.A O no hydrogen 2.850 N/A ALA 150.A N SER 147.A O no hydrogen 2.999 N/A LEU 151.A N PHE 144.A O no hydrogen 2.883 N/A PHE 154.A N ALA 150.A O no hydrogen 3.125 N/A GLN 155.A N LEU 151.A O no hydrogen 2.787 N/A THR 156.A N PRO 152.A O no hydrogen 3.049 N/A THR 156.A OG1 PRO 152.A O no hydrogen 3.077 N/A THR 157.A N ALA 153.A O no hydrogen 3.029 N/A THR 157.A OG1 ALA 153.A O no hydrogen 3.314 N/A TYR 158.A N PHE 154.A O no hydrogen 2.923 N/A TYR 158.A OH ASP 209.A OD1 no hydrogen 2.547 N/A GLY 159.A N GLN 155.A O no hydrogen 2.951 N/A PHE 160.A N GLN 155.A O no hydrogen 3.169 N/A GLN 165.A N LYS 162.A O no hydrogen 2.825 N/A LEU 166.A N PRO 163.A O no hydrogen 3.193 N/A ILE 167.A N LEU 138.A O no hydrogen 2.842 N/A LEU 169.A N ALA 140.A O no hydrogen 2.849 N/A THR 174.A OG1 ASP 196.A OD2 no hydrogen 2.767 N/A ALA 175.A N ASP 173.A OD1 no hydrogen 2.956 N/A THR 177.A OG1 THR 174.A O no hydrogen 3.110 N/A ILE 178.A N THR 174.A O no hydrogen 2.903 N/A ALA 179.A N ALA 175.A O no hydrogen 3.158 N/A ALA 180.A N ALA 176.A O no hydrogen 3.038 N/A ALA 181.A N THR 177.A O no hydrogen 3.163 N/A ALA 182.A N ILE 178.A O no hydrogen 2.912 N/A ASN 183.A N ALA 179.A O no hydrogen 2.870 N/A GLN 184.A N ALA 181.A O no hydrogen 3.367 N/A THR 185.A N ALA 180.A O no hydrogen 3.008 N/A ASN 187.A N GLN 184.A O no hydrogen 2.995 N/A ALA 188.A N THR 185.A O no hydrogen 2.898 N/A ASN 189.A N VAL 137.A O no hydrogen 2.934 N/A ASN 189.A ND2 THR 135.A O no hydrogen 3.009 N/A ALA 190.A N VAL 137.A O no hydrogen 3.182 N/A ALA 191.A N ALA 109.A O no hydrogen 2.872 N/A TYR 193.A N ASP 196.A OD2 no hydrogen 2.941 N/A GLY 194.A N THR 105.A O no hydrogen 2.941 N/A THR 195.A N ASN 104.A OD1 no hydrogen 3.351 N/A THR 195.A OG1 GLU 12.A OE1 no hydrogen 2.538 N/A THR 195.A OG1 GLU 12.A OE2 no hydrogen 3.568 N/A ASP 196.A N TYR 193.A O no hydrogen 2.926 N/A ILE 199.A N ASP 196.A O no hydrogen 3.148 N/A ALA 200.A N GLY 197.A O no hydrogen 3.382 N/A SER 202.A OG.A GLY 198.A O no hydrogen 2.777 N/A SER 202.A OG.B GLY 198.A O no hydrogen 2.752 N/A SER 202.A OG.B ILE 199.A O no hydrogen 2.716 N/A VAL 205.A N LEU 110.A O no hydrogen 2.794 N/A LEU 207.A N ILE 108.A O no hydrogen 2.954 N/A GLU 208.A N LYS 121.A O no hydrogen 3.025 N/A LYS 211.A N TYR 158.A OH no hydrogen 2.815 N/A HIS 212.A N ASP 209.A O no hydrogen 2.966 N/A VAL 213.A N ASP 209.A OD1 no hydrogen 2.956 N/A GLN 214.A N ASP 209.A OD2 no hydrogen 2.894 N/A GLN 214.A NE2 ALA 149.A O no hydrogen 2.768 N/A VAL 216.A N TRP 74.A O no hydrogen 2.859 N/A TYR 217.A N ASN 103.A OD1 no hydrogen 2.987 N/A GLN 218.A N THR 59.A OG1 no hydrogen 3.060 N/A GLN 218.A NE2.A SER 100.A O no hydrogen 2.786 N/A GLN 218.A NE2.B PRO 101.A O no hydrogen 3.489 N/A ALA 220.A N GLU 57.A O no hydrogen 2.803 N/A ILE 222.A N TYR 55.A O no hydrogen 2.922 N/A ILE 223.A N VAL 95.A O no hydrogen 2.964 N/A ARG 224.A N ASP 53.A O no hydrogen 2.971 N/A ARG 224.A NE ILE 52.A O no hydrogen 3.262 N/A ARG 224.A NE ASP 53.A OD1 no hydrogen 2.910 N/A ARG 224.A NH1 GLU 226.A OE2 no hydrogen 2.819 N/A ARG 224.A NH2 ASP 53.A OD1 no hydrogen 2.716 N/A GLU 225.A N LYS 93.A O no hydrogen 2.914 N/A VAL 227.A N ARG 224.A O no hydrogen 3.046 N/A LEU 228.A N ARG 224.A O no hydrogen 3.107 N/A LYS 229.A N GLU 225.A O no hydrogen 2.857 N/A LYS 230.A N GLU 226.A O no hydrogen 3.351 N/A HIS 231.A N VAL 227.A O no hydrogen 3.044 N/A HIS 231.A N LEU 228.A O no hydrogen 3.024 N/A ILE 234.A N HIS 231.A O no hydrogen 3.096 N/A LEU 237.A N ASN 233.A O no hydrogen 2.978 N/A LEU 238.A N ILE 234.A O no hydrogen 3.076 N/A LYS 239.A N GLU 235.A O no hydrogen 3.260 N/A LYS 239.A NZ GLU 243.A OE2 no hydrogen 2.938 N/A PHE 242.A N LEU 238.A O no hydrogen 3.015 N/A GLU 243.A N LYS 239.A O no hydrogen 3.026 N/A LYS 244.A N PRO 240.A O no hydrogen 3.272 N/A LYS 244.A N VAL 241.A O no hydrogen 3.248 N/A LEU 245.A N PHE 242.A O no hydrogen 3.048 N/A ASP 246.A N LYS 244.A O no hydrogen 3.012 N/A THR 249.A N ASP 246.A OD1 no hydrogen 2.954 N/A THR 249.A OG1 ASP 246.A OD1 no hydrogen 2.684 N/A LEU 250.A N ASP 246.A O no hydrogen 2.976 N/A GLN 251.A N LEU 247.A O no hydrogen 2.893 N/A GLN 251.A NE2 GLY 194.A O no hydrogen 2.891 N/A ASP 252.A N ALA 248.A O no hydrogen 2.989 N/A LEU 253.A N THR 249.A O no hydrogen 2.998 N/A ASN 254.A N LEU 250.A O no hydrogen 2.929 N/A ASN 254.A ND2 GLU 12.A OE1 no hydrogen 2.955 N/A ASN 254.A ND2 THR 195.A O no hydrogen 2.943 N/A ALA 255.A N GLN 251.A O no hydrogen 2.900 N/A ARG 256.A N ASP 252.A O no hydrogen 2.997 N/A ARG 256.A NE.A ASP 252.A OD1.A no hydrogen 3.194 N/A ARG 256.A NE.B GLU 262.A OE2 no hydrogen 3.173 N/A ARG 256.A NH1.A ASP 252.A OD1.A no hydrogen 2.959 N/A ARG 256.A NH1.B GLU 262.A OE1 no hydrogen 3.041 N/A ARG 256.A NH1.B ASP 269.A OD2 no hydrogen 2.867 N/A VAL 257.A N LEU 253.A O no hydrogen 3.436 N/A GLN 258.A N ASN 254.A O no hydrogen 2.820 N/A GLN 258.A NE2.A THR 11.A OG1 no hydrogen 3.164 N/A GLN 258.A NE2.B THR 11.A OG1 no hydrogen 2.881 N/A VAL 259.A N ALA 255.A O no hydrogen 2.690 N/A GLY 260.A N ALA 255.A O no hydrogen 2.872 N/A GLY 261.A N VAL 257.A O no hydrogen 3.186 N/A GLU 262.A N ARG 256.A O no hydrogen 2.970 N/A VAL 267.A N GLN 263.A O no hydrogen 3.059 N/A ALA 268.A N ALA 264.A O no hydrogen 2.870 N/A PHE 270.A N VAL 267.A O no hydrogen 3.020 N/A LEU 271.A N ALA 268.A O no hydrogen 3.026 N/A THR 272.A OG1.A ASP 269.A O no hydrogen 3.139 N/A LYS 273.A N ASP 269.A O no hydrogen 2.953 N/A ASN 274.A N PHE 270.A O no hydrogen 3.252 N/A ASN 274.A N LEU 271.A O no hydrogen 3.203 N/A ASN 274.A ND2 PHE 270.A O no hydrogen 2.758 N/A GLY 275.A N THR 272.A O no hydrogen 3.280 N/A PHE 276.A N LEU 271.A O no hydrogen 2.827 N/A LYS 278.A N GLN 26.A OE1 no hydrogen 3.057 N/A