Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4nhe_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 2.A N GLU 25.A O no hydrogen 2.916 N/A LYS 3.A N ASP 64.A OD2 no hydrogen 2.596 N/A LEU 4.A N GLN 27.A O no hydrogen 2.841 N/A GLY 5.A N LEU 65.A O no hydrogen 2.835 N/A VAL 6.A N ALA 30.A O no hydrogen 2.951 N/A ILE 7.A N TYR 67.A O no hydrogen 2.897 N/A SER 13.A N GLY 10.A O no hydrogen 2.979 N/A SER 13.A OG GLY 8.A O no hydrogen 2.582 N/A HIS 14.A N GLY 10.A O no hydrogen 3.483 N/A HIS 14.A ND1 TYR 46.A OH no hydrogen 2.942 N/A HIS 15.A N ALA 11.A O no hydrogen 2.963 N/A PHE 16.A N ILE 12.A O no hydrogen 2.854 N/A ILE 17.A N SER 13.A O no hydrogen 2.971 N/A GLU 18.A N HIS 14.A O no hydrogen 2.948 N/A ALA 19.A N HIS 15.A O no hydrogen 3.074 N/A ALA 20.A N PHE 16.A O no hydrogen 2.762 N/A HIS 21.A N ILE 17.A O no hydrogen 2.782 N/A THR 22.A N GLU 18.A O no hydrogen 3.202 N/A THR 22.A OG1 GLU 18.A O no hydrogen 2.687 N/A SER 23.A N ALA 19.A O no hydrogen 3.040 N/A SER 23.A OG ALA 20.A O no hydrogen 2.847 N/A GLY 24.A N HIS 21.A O no hydrogen 3.181 N/A GLU 25.A N SER 23.A OG no hydrogen 3.204 N/A TYR 26.A OH VAL 281.A O no hydrogen 2.750 N/A GLN 27.A N LEU 2.A O no hydrogen 2.761 N/A LEU 28.A N HIS 21.A NE2 no hydrogen 3.097 N/A VAL 29.A N LEU 4.A O no hydrogen 2.920 N/A ALA 30.A N LEU 4.A O no hydrogen 3.377 N/A ILE 31.A N GLN 50.A O no hydrogen 2.968 N/A TYR 32.A N VAL 6.A O no hydrogen 3.011 N/A SER 33.A N PHE 52.A O no hydrogen 2.892 N/A SER 33.A OG LYS 35.A O no hydrogen 3.206 N/A SER 33.A OG THR 38.A OG1 no hydrogen 2.263 N/A LYS 35.A N SER 33.A OG no hydrogen 3.341 N/A GLU 37.A N GLU 37.A OE1 no hydrogen 2.781 N/A THR 38.A OG1 SER 33.A OG no hydrogen 2.263 N/A THR 38.A OG1 LYS 35.A O no hydrogen 2.629 N/A ALA 39.A N LYS 35.A O no hydrogen 3.145 N/A ALA 40.A N LEU 36.A O no hydrogen 2.816 N/A THR 41.A N GLU 37.A O no hydrogen 2.942 N/A THR 41.A OG1 GLU 37.A O no hydrogen 3.004 N/A PHE 42.A N THR 38.A O no hydrogen 3.036 N/A ALA 43.A N ALA 39.A O no hydrogen 2.755 N/A SER 44.A OG THR 41.A O no hydrogen 3.215 N/A TYR 46.A N ALA 43.A O no hydrogen 2.788 N/A TYR 46.A OH HIS 14.A ND1 no hydrogen 2.942 N/A GLN 50.A N VAL 29.A O no hydrogen 2.992 N/A PHE 52.A N ILE 31.A O no hydrogen 2.865 N/A PHE 58.A N GLN 54.A O no hydrogen 2.801 N/A PHE 59.A N LEU 55.A O no hydrogen 2.960 N/A LYS 60.A N VAL 57.A O no hydrogen 3.181 N/A SER 61.A N PHE 58.A O no hydrogen 3.138 N/A SER 62.A OG SER 62.A O no hydrogen 2.289 N/A ASP 64.A N LYS 3.A O no hydrogen 2.898 N/A LEU 65.A N LYS 3.A O no hydrogen 3.200 N/A VAL 66.A N HIS 88.A O no hydrogen 2.841 N/A TYR 67.A N GLY 5.A O no hydrogen 2.957 N/A TYR 67.A OH GLU 92.A OE1 no hydrogen 2.555 N/A ILE 68.A N ILE 90.A O no hydrogen 2.855 N/A ALA 69.A N ILE 7.A O no hydrogen 2.796 N/A SER 70.A OG GLN 78.A OE1 no hydrogen 2.670 N/A ASN 72.A ND2 ALA 171.A O no hydrogen 2.965 N/A SER 73.A OG ARG 169.A O no hydrogen 3.263 N/A LEU 74.A N PRO 71.A O no hydrogen 2.962 N/A HIS 75.A N ASN 72.A O no hydrogen 3.179 N/A HIS 75.A ND1 PRO 94.A O no hydrogen 2.825 N/A HIS 75.A NE2 SER 70.A O no hydrogen 2.762 N/A GLN 78.A N LEU 74.A O no hydrogen 3.266 N/A ALA 79.A N HIS 75.A O no hydrogen 2.850 N/A LYS 80.A N PHE 76.A O no hydrogen 2.892 N/A LYS 80.A NZ THR 108.A OG1 no hydrogen 2.718 N/A ALA 81.A N ALA 77.A O no hydrogen 3.112 N/A ALA 82.A N GLN 78.A O no hydrogen 2.955 N/A LEU 83.A N ALA 79.A O no hydrogen 2.955 N/A SER 84.A N LYS 80.A O no hydrogen 3.013 N/A SER 84.A OG LYS 80.A O no hydrogen 3.049 N/A ALA 85.A N ALA 81.A O no hydrogen 3.060 N/A ALA 85.A N ALA 82.A O no hydrogen 3.106 N/A GLY 86.A N LEU 83.A O no hydrogen 2.872 N/A LYS 87.A N ALA 82.A O no hydrogen 3.023 N/A LYS 87.A NZ PHE 59.A O no hydrogen 3.142 N/A LYS 87.A NZ SER 61.A O no hydrogen 2.770 N/A HIS 88.A N ASP 64.A O no hydrogen 2.884 N/A VAL 89.A N PHE 115.A O no hydrogen 3.058 N/A ILE 90.A N VAL 66.A O no hydrogen 3.013 N/A LEU 91.A N PHE 117.A O no hydrogen 2.821 N/A GLU 92.A N ILE 68.A O no hydrogen 3.048 N/A LYS 93.A N GLU 92.A OE2 no hydrogen 3.028 N/A LYS 93.A NZ ASP 177.A O no hydrogen 2.820 N/A ALA 95.A N GLU 118.A OE2 no hydrogen 2.672 N/A SER 97.A N GLU 101.A OE1 no hydrogen 3.057 N/A SER 97.A OG GLU 101.A OE1 no hydrogen 3.178 N/A SER 97.A OG GLU 101.A OE2 no hydrogen 3.334 N/A GLN 100.A NE2 ASP 104.A OD1 no hydrogen 3.154 N/A GLU 101.A N GLN 98.A O no hydrogen 3.077 N/A TRP 102.A NE1 LEU 300.A O no hydrogen 3.125 N/A PHE 103.A N PRO 99.A O no hydrogen 3.228 N/A ASP 104.A N GLN 100.A O no hydrogen 2.942 N/A LEU 105.A N GLU 101.A O no hydrogen 2.963 N/A ILE 106.A N TRP 102.A O no hydrogen 3.080 N/A GLN 107.A N PHE 103.A O no hydrogen 3.191 N/A THR 108.A N ASP 104.A O no hydrogen 3.006 N/A THR 108.A OG1 ASP 104.A O no hydrogen 2.965 N/A ALA 109.A N LEU 105.A O no hydrogen 2.731 N/A GLU 110.A N ILE 106.A O no hydrogen 2.930 N/A LYS 111.A N GLN 107.A O no hydrogen 3.002 N/A ASN 112.A N THR 108.A O no hydrogen 3.200 N/A ASN 112.A ND2 THR 108.A O no hydrogen 2.658 N/A ASN 113.A N GLU 110.A O no hydrogen 3.121 N/A CYS 114.A N ALA 109.A O no hydrogen 3.020 N/A CYS 114.A SG LYS 87.A O no hydrogen 3.596 N/A CYS 114.A SG ASN 112.A O no hydrogen 3.372 N/A PHE 115.A N HIS 88.A ND1 no hydrogen 2.924 N/A ILE 116.A N TYR 296.A OH no hydrogen 3.016 N/A PHE 117.A N VAL 89.A O no hydrogen 2.884 N/A ALA 119.A N LEU 91.A O no hydrogen 2.875 N/A ALA 120.A N GLU 118.A O no hydrogen 2.730 N/A ARG 121.A NH1 GLU 251.A OE2 no hydrogen 2.936 N/A ARG 121.A NH2 GLU 251.A OE2 no hydrogen 3.104 N/A ASN 122.A ND2 TYR 181.A O no hydrogen 3.056 N/A ASN 122.A ND2 ILE 250.A O no hydrogen 2.949 N/A TYR 123.A OH ASP 302.A OD2 no hydrogen 2.643 N/A GLU 125.A N ASN 122.A O no hydrogen 3.022 N/A LYS 126.A N GLU 279.A OE2 no hydrogen 2.842 N/A PHE 128.A N GLU 125.A O no hydrogen 3.087 N/A THR 130.A N LYS 126.A O no hydrogen 3.122 N/A THR 130.A OG1 LYS 126.A O no hydrogen 3.430 N/A ILE 131.A N ALA 127.A O no hydrogen 2.701 N/A LYS 132.A N PHE 128.A O no hydrogen 2.899 N/A LYS 132.A NZ ARG 188.A O no hydrogen 3.043 N/A ASN 133.A N THR 129.A O no hydrogen 3.045 N/A PHE 134.A N THR 130.A O no hydrogen 3.134 N/A LEU 135.A N ILE 131.A O no hydrogen 3.009 N/A ALA 136.A N ASN 133.A O no hydrogen 3.178 N/A LYS 138.A N LEU 135.A O no hydrogen 2.881 N/A LYS 138.A NZ ASP 242.A OD2 no hydrogen 2.435 N/A LEU 141.A N TYR 239.A O no hydrogen 2.683 N/A ALA 143.A N GLN 221.A O no hydrogen 3.066 N/A ASP 144.A N GLU 237.A O no hydrogen 2.873 N/A PHE 145.A N HIS 223.A O no hydrogen 2.914 N/A ASN 146.A ND2 LEU 234.A O no hydrogen 2.832 N/A TYR 147.A N LYS 225.A O no hydrogen 3.011 N/A LYS 149.A N GLY 227.A O no hydrogen 3.029 N/A SER 151.A N LYS 228.A O no hydrogen 2.921 N/A LYS 153.A N SER 151.A OG no hydrogen 2.957 N/A MET 154.A N SER 151.A O no hydrogen 3.054 N/A LEU 157.A N LYS 153.A O no hydrogen 3.063 N/A LEU 158.A N MET 154.A O no hydrogen 2.825 N/A ALA 159.A N PRO 155.A O no hydrogen 3.002 N/A GLY 160.A N LEU 157.A O no hydrogen 2.901 N/A GLN 161.A N ASP 156.A O no hydrogen 2.962 N/A PHE 166.A N PRO 163.A O no hydrogen 2.853 N/A SER 167.A N ASN 164.A O no hydrogen 3.094 N/A ARG 169.A N SER 167.A OG no hydrogen 2.864 N/A GLY 172.A N SER 167.A O no hydrogen 3.255 N/A GLY 173.A N VAL 165.A O no hydrogen 2.891 N/A ALA 174.A N ASP 208.A O no hydrogen 2.911 N/A LEU 175.A N ASP 208.A OD2 no hydrogen 2.817 N/A ASP 177.A N GLY 173.A O no hydrogen 2.918 N/A LEU 178.A N ALA 174.A O no hydrogen 2.766 N/A GLY 179.A N ALA 174.A O no hydrogen 2.868 N/A TYR 181.A N LEU 178.A O no hydrogen 3.006 N/A LEU 183.A N GLY 179.A O no hydrogen 3.244 N/A TYR 184.A N ILE 180.A O no hydrogen 2.887 N/A TYR 184.A OH GLU 118.A OE1 no hydrogen 2.620 N/A ALA 185.A N TYR 181.A O no hydrogen 2.986 N/A ALA 186.A N PRO 182.A O no hydrogen 2.964 N/A VAL 187.A N LEU 183.A O no hydrogen 2.931 N/A ARG 188.A N TYR 184.A O no hydrogen 2.881 N/A ARG 188.A NE TYR 123.A O no hydrogen 3.362 N/A ARG 188.A NH1 ARG 188.A O no hydrogen 3.516 N/A LEU 189.A N ALA 185.A O no hydrogen 3.050 N/A PHE 190.A N ALA 186.A O no hydrogen 2.685 N/A GLY 191.A N VAL 187.A O no hydrogen 2.882 N/A LYS 192.A NZ SER 305.A OG no hydrogen 2.945 N/A ASN 194.A N PHE 216.A O no hydrogen 2.608 N/A THR 197.A N ILE 214.A O no hydrogen 2.978 N/A TYR 198.A N THR 316.A OG1 no hydrogen 2.946 N/A TYR 198.A OH ASP 208.A OD2 no hydrogen 2.832 N/A HIS 199.A N ASP 212.A O no hydrogen 2.936 N/A GLN 201.A N ASN 210.A O no hydrogen 2.905 N/A GLN 202.A NE2 SER 206.A O no hydrogen 2.848 N/A GLN 202.A NE2 ALA 317.A O no hydrogen 3.132 N/A GLN 202.A NE2 GLY 318.A O no hydrogen 3.110 N/A LEU 203.A N ILE 207.A O no hydrogen 2.823 N/A ASN 205.A ND2 PHE 166.A O no hydrogen 3.030 N/A SER 206.A N LEU 203.A O no hydrogen 2.943 N/A SER 206.A OG ASN 205.A O no hydrogen 2.736 N/A SER 206.A OG GLY 318.A O no hydrogen 3.564 N/A SER 206.A OG ARG 320.A O no hydrogen 3.122 N/A ILE 207.A N ASN 205.A OD1 no hydrogen 2.947 N/A LEU 209.A N GLN 201.A O no hydrogen 2.868 N/A ASN 210.A ND2 ASN 229.A OD1 no hydrogen 2.901 N/A GLY 211.A N ALA 226.A O no hydrogen 2.832 N/A ASP 212.A N HIS 199.A O no hydrogen 2.933 N/A GLY 213.A N ILE 224.A O no hydrogen 2.722 N/A ILE 214.A N THR 197.A O no hydrogen 2.954 N/A LEU 215.A N VAL 222.A O no hydrogen 2.820 N/A PHE 216.A N ASP 195.A O no hydrogen 2.800 N/A TYR 217.A N TYR 220.A O no hydrogen 2.843 N/A TYR 217.A OH GLY 191.A O no hydrogen 2.642 N/A VAL 222.A N LEU 215.A O no hydrogen 2.920 N/A HIS 223.A N ALA 143.A O no hydrogen 2.942 N/A HIS 223.A ND1 GLY 213.A O no hydrogen 3.237 N/A ILE 224.A N GLY 213.A O no hydrogen 2.801 N/A LYS 225.A N PHE 145.A O no hydrogen 3.116 N/A LYS 225.A NZ ASP 212.A OD1 no hydrogen 2.578 N/A LYS 225.A NZ ASP 212.A OD2 no hydrogen 3.506 N/A ALA 226.A N GLY 211.A O no hydrogen 3.088 N/A GLY 227.A N TYR 147.A O no hydrogen 3.353 N/A LYS 228.A N LEU 209.A O no hydrogen 2.735 N/A LYS 228.A NZ ASP 177.A OD1 no hydrogen 2.641 N/A SER 232.A N ALA 148.A O no hydrogen 3.036 N/A LEU 234.A N SER 232.A OG no hydrogen 3.327 N/A CYS 236.A N LEU 247.A O no hydrogen 2.750 N/A GLU 237.A N ASP 144.A O no hydrogen 2.953 N/A ILE 238.A N LEU 245.A O no hydrogen 2.816 N/A TYR 239.A N GLY 142.A O no hydrogen 2.821 N/A TYR 239.A OH GLU 237.A OE1 no hydrogen 2.761 N/A THR 240.A N GLY 243.A O no hydrogen 2.836 N/A THR 240.A OG1 ASP 242.A OD1 no hydrogen 2.536 N/A THR 240.A OG1 GLY 243.A O no hydrogen 3.285 N/A THR 241.A N GLN 139.A O no hydrogen 3.053 N/A GLY 243.A N THR 240.A O no hydrogen 3.259 N/A THR 244.A N THR 259.A O no hydrogen 2.837 N/A LEU 245.A N ILE 238.A O no hydrogen 2.786 N/A THR 246.A N ILE 257.A O no hydrogen 2.820 N/A LEU 247.A N CYS 236.A O no hydrogen 2.739 N/A ASN 248.A N SER 255.A O no hydrogen 3.215 N/A THR 249.A OG1 GLU 251.A O no hydrogen 2.600 N/A GLU 251.A N THR 249.A OG1 no hydrogen 3.267 N/A HIS 252.A N GLU 125.A OE2 no hydrogen 2.571 N/A HIS 252.A NE2 ALA 273.A O no hydrogen 2.806 N/A ILE 253.A N GLU 125.A OE1 no hydrogen 2.865 N/A ARG 254.A N ASN 248.A OD1 no hydrogen 2.822 N/A SER 255.A N ASN 248.A OD1 no hydrogen 3.094 N/A ILE 257.A N THR 246.A O no hydrogen 2.876 N/A PHE 258.A N VAL 266.A O no hydrogen 2.793 N/A THR 259.A N THR 244.A O no hydrogen 2.941 N/A ASP 260.A N ASN 264.A O no hydrogen 2.927 N/A GLN 262.A N ASP 260.A OD1 no hydrogen 2.728 N/A GLY 263.A N ASP 260.A O no hydrogen 2.998 N/A ASN 264.A N ASP 260.A OD1 no hydrogen 3.070 N/A ASN 264.A ND2 ASP 260.A OD2 no hydrogen 3.294 N/A GLN 265.A NE2 THR 259.A OG1 no hydrogen 3.111 N/A VAL 266.A N PHE 258.A O no hydrogen 2.752 N/A LEU 268.A N ALA 256.A O no hydrogen 2.939 N/A GLN 272.A NE2 HIS 252.A O no hydrogen 2.910 N/A THR 278.A N HIS 275.A O no hydrogen 3.430 N/A THR 278.A OG1 HIS 275.A O no hydrogen 3.323 N/A VAL 281.A N MET 277.A O no hydrogen 2.973 N/A ALA 282.A N THR 278.A O no hydrogen 3.124 N/A ALA 283.A N GLU 279.A O no hydrogen 2.992 N/A PHE 284.A N GLU 280.A O no hydrogen 2.912 N/A ALA 285.A N VAL 281.A O no hydrogen 3.316 N/A HIS 286.A N ALA 282.A O no hydrogen 2.850 N/A MET 287.A N ALA 283.A O no hydrogen 2.922 N/A ILE 288.A N PHE 284.A O no hydrogen 3.138 N/A GLN 289.A N ALA 285.A O no hydrogen 3.068 N/A GLN 289.A NE2 GLU 25.A OE1 no hydrogen 2.593 N/A GLN 290.A N HIS 286.A O no hydrogen 2.818 N/A LEU 295.A N ASP 292.A OD1 no hydrogen 2.870 N/A TYR 296.A N ASP 292.A O no hydrogen 3.056 N/A GLN 297.A N LEU 293.A O no hydrogen 2.918 N/A THR 298.A N ASN 294.A O no hydrogen 3.238 N/A THR 298.A OG1 LEU 295.A O no hydrogen 2.796 N/A TRP 299.A N LEU 295.A O no hydrogen 3.072 N/A LEU 300.A N TYR 296.A O no hydrogen 3.045 N/A TYR 301.A N GLN 297.A O no hydrogen 2.938 N/A ASP 302.A N THR 298.A O no hydrogen 2.770 N/A ALA 303.A N TRP 299.A O no hydrogen 3.038 N/A GLY 304.A N LEU 300.A O no hydrogen 3.022 N/A SER 305.A N TYR 301.A O no hydrogen 2.990 N/A SER 305.A OG TYR 301.A O no hydrogen 3.405 N/A VAL 306.A N ASP 302.A O no hydrogen 2.949 N/A HIS 307.A N ALA 303.A O no hydrogen 2.985 N/A HIS 307.A NE2 GLU 118.A OE1 no hydrogen 2.892 N/A HIS 307.A NE2 GLU 118.A OE2 no hydrogen 3.013 N/A GLU 308.A N GLY 304.A O no hydrogen 2.989 N/A LEU 309.A N SER 305.A O no hydrogen 3.059 N/A LEU 310.A N VAL 306.A O no hydrogen 2.878 N/A TYR 311.A N HIS 307.A O no hydrogen 3.091 N/A THR 312.A N GLU 308.A O no hydrogen 3.015 N/A THR 312.A OG1 GLU 308.A O no hydrogen 3.176 N/A MET 313.A N LEU 309.A O no hydrogen 2.895 N/A ARG 314.A N LEU 310.A O no hydrogen 2.846 N/A ARG 314.A NH1 SER 97.A O no hydrogen 2.928 N/A ARG 314.A NH1 GLU 324.A OE2 no hydrogen 2.784 N/A ARG 314.A NH2 ILE 319.A O no hydrogen 2.920 N/A ARG 314.A NH2 GLU 324.A OE1 no hydrogen 3.037 N/A GLN 315.A N TYR 311.A O no hydrogen 3.014 N/A THR 316.A N THR 312.A O no hydrogen 2.989 N/A THR 316.A OG1 TYR 198.A O no hydrogen 2.948 N/A THR 316.A OG1 MET 313.A O no hydrogen 3.044 N/A ALA 317.A N MET 313.A O no hydrogen 3.123 N/A ILE 319.A N ARG 314.A O no hydrogen 2.898 N/A ARG 320.A N SER 206.A OG no hydrogen 2.768 N/A PHE 321.A N GLU 324.A OE1 no hydrogen 2.891 N/A GLU 322.A N ASP 168.A O no hydrogen 2.815 N/A GLU 324.A N PHE 321.A O no hydrogen 2.845 N/A LYS 325.A N GLU 322.A O no hydrogen 3.245 N/A LYS 325.A NZ ASP 168.A OD2 no hydrogen 2.992 N/A LYS 325.A NZ ASN 205.A O no hydrogen 2.782 N/A