Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4nkt_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 3.A N ASP 1.A OD1 no hydrogen 3.138 N/A SER 3.A OG ASP 1.A OD1 no hydrogen 2.450 N/A SER 3.A OG HIS 4.A ND1 no hydrogen 2.711 N/A HIS 4.A ND1 SER 3.A OG no hydrogen 2.711 N/A HIS 4.A NE2 HIS 229.A ND1 no hydrogen 2.823 N/A THR 8.A N HIS 4.A O no hydrogen 2.924 N/A THR 8.A OG1 HIS 4.A O no hydrogen 2.813 N/A THR 8.A OG1 SER 223.A OG no hydrogen 3.194 N/A LYS 9.A N LYS 5.A O no hydrogen 3.019 N/A LYS 9.A NZ GLU 13.A OE2 no hydrogen 2.649 N/A PHE 10.A N GLU 6.A O no hydrogen 3.092 N/A CYS 11.A N PHE 7.A O no hydrogen 2.775 N/A CYS 11.A SG PHE 7.A O no hydrogen 3.298 N/A TYR 12.A N THR 8.A O no hydrogen 3.042 N/A GLU 13.A N LYS 9.A O no hydrogen 3.100 N/A VAL 14.A N PHE 10.A O no hydrogen 2.926 N/A TYR 15.A N CYS 11.A O no hydrogen 2.843 N/A ASN 16.A N TYR 12.A O no hydrogen 3.000 N/A GLU 17.A N VAL 14.A O no hydrogen 2.901 N/A ILE 18.A N VAL 14.A O no hydrogen 3.005 N/A ILE 18.A N TYR 15.A O no hydrogen 3.227 N/A LYS 19.A N TYR 15.A O no hydrogen 3.036 N/A LYS 19.A NZ ASN 16.A OD1 no hydrogen 2.588 N/A ILE 20.A N ALA 59.A O no hydrogen 3.360 N/A GLU 24.A N SER 21.A OG no hydrogen 3.099 N/A PHE 25.A N SER 21.A O no hydrogen 2.948 N/A LYS 26.A N ASP 22.A O no hydrogen 2.925 N/A GLU 27.A N LYS 23.A O no hydrogen 3.121 N/A LYS 28.A N GLU 24.A O no hydrogen 3.052 N/A ARG 29.A N PHE 25.A O no hydrogen 2.970 N/A ARG 29.A NH2 GLU 55.A OE1 no hydrogen 2.721 N/A ALA 30.A N LYS 26.A O no hydrogen 2.817 N/A ALA 31.A N GLU 27.A O no hydrogen 2.837 N/A LEU 32.A N LYS 28.A O no hydrogen 2.918 N/A ASP 33.A N ARG 29.A O no hydrogen 2.952 N/A THR 34.A N ALA 30.A O no hydrogen 3.076 N/A THR 34.A OG1 ALA 30.A O no hydrogen 3.305 N/A LEU 35.A N ALA 31.A O no hydrogen 2.973 N/A ARG 36.A N LEU 32.A O no hydrogen 2.907 N/A ARG 36.A NE GLU 47.A OE2 no hydrogen 3.046 N/A ARG 36.A NE LEU 48.A O no hydrogen 3.390 N/A ARG 36.A NH2 LEU 48.A O no hydrogen 2.909 N/A LEU 37.A N ASP 33.A O no hydrogen 3.094 N/A CYS 38.A N THR 34.A O no hydrogen 3.137 N/A CYS 38.A SG.A GLU 84.A OE2 no hydrogen 3.671 N/A CYS 38.A SG.B THR 34.A O no hydrogen 3.460 N/A CYS 38.A SG.B GLU 84.A OE1 no hydrogen 3.164 N/A LEU 39.A N LEU 35.A O no hydrogen 3.021 N/A LYS 40.A N ARG 36.A O no hydrogen 3.033 N/A LYS 40.A NZ PRO 44.A O no hydrogen 2.923 N/A LYS 40.A NZ ALA 46.A O no hydrogen 2.813 N/A LYS 40.A NZ GLU 47.A OE1 no hydrogen 3.195 N/A ARG 41.A N CYS 38.A O no hydrogen 3.137 N/A ILE 42.A N LEU 39.A O no hydrogen 2.750 N/A SER 43.A N LEU 39.A O no hydrogen 3.112 N/A ASP 45.A N SER 43.A OG no hydrogen 3.019 N/A GLU 47.A N LEU 70.A O no hydrogen 3.033 N/A LEU 48.A N GLU 47.A OE2 no hydrogen 3.177 N/A VAL 49.A N CYS 68.A O no hydrogen 2.816 N/A PHE 51.A N ASP 66.A O no hydrogen 3.077 N/A GLY 52.A N THR 128.A OG1 no hydrogen 2.925 N/A SER 56.A N GLY 52.A O no hydrogen 3.061 N/A SER 56.A OG GLY 52.A O no hydrogen 3.369 N/A SER 56.A OG SER 53.A O no hydrogen 3.349 N/A GLY 57.A N SER 53.A O no hydrogen 2.935 N/A LEU 58.A N SER 53.A O no hydrogen 2.767 N/A LYS 61.A N ILE 18.A O no hydrogen 2.897 N/A LYS 61.A NZ GLU 17.A O no hydrogen 3.032 N/A ASN 62.A N GLU 24.A OE1 no hydrogen 2.834 N/A SER 63.A N GLU 24.A OE2 no hydrogen 3.209 N/A SER 63.A OG LEU 60.A O no hydrogen 2.454 N/A MET 65.A N GLN 114.A O no hydrogen 3.133 N/A LEU 67.A N ALA 116.A O no hydrogen 2.802 N/A CYS 68.A N VAL 49.A O no hydrogen 2.774 N/A VAL 69.A N GLY 118.A O no hydrogen 2.809 N/A LEU 70.A N GLU 47.A O no hydrogen 2.848 N/A MET 71.A N ASN 120.A OD1 no hydrogen 2.873 N/A PHE 77.A N ILE 73.A O no hydrogen 2.804 N/A TYR 78.A N ALA 74.A O no hydrogen 2.928 N/A TYR 78.A OH GLY 88.A O no hydrogen 2.972 N/A GLU 79.A N LEU 75.A O no hydrogen 2.908 N/A GLU 80.A N GLN 76.A O no hydrogen 3.031 N/A LEU 81.A N PHE 77.A O no hydrogen 2.869 N/A ILE 82.A N TYR 78.A O no hydrogen 3.092 N/A ALA 83.A N GLU 79.A O no hydrogen 3.108 N/A GLU 84.A N GLU 80.A O no hydrogen 3.051 N/A GLU 84.A N LEU 81.A O no hydrogen 3.172 N/A GLY 85.A N ILE 82.A O no hydrogen 2.875 N/A PHE 86.A N LEU 81.A O no hydrogen 3.137 N/A GLU 87.A N SER 103.A O no hydrogen 2.851 N/A LYS 89.A N LYS 100.A O no hydrogen 2.828 N/A ILE 99.A N ILE 117.A O no hydrogen 2.913 N/A LYS 100.A N LYS 89.A O no hydrogen 2.929 N/A LEU 101.A N CYS 115.A O no hydrogen 2.701 N/A THR 102.A N GLU 87.A O no hydrogen 2.775 N/A THR 102.A OG1 GLU 87.A O no hydrogen 3.421 N/A SER 103.A OG ALA 111.A O no hydrogen 3.031 N/A ASP 104.A N GLY 110.A O no hydrogen 3.172 N/A THR 105.A N GLY 85.A O no hydrogen 2.921 N/A THR 105.A OG1 GLY 85.A O no hydrogen 2.861 N/A LYS 106.A N ASP 104.A OD1 no hydrogen 3.004 N/A ASN 107.A N ASP 104.A OD1 no hydrogen 2.884 N/A ASN 107.A ND2 GLU 84.A O no hydrogen 3.170 N/A ASN 107.A ND2 ASP 104.A OD1 no hydrogen 2.836 N/A PHE 109.A N ASP 104.A OD2 no hydrogen 2.875 N/A SER 112.A OG SER 112.A O no hydrogen 2.310 N/A PHE 113.A N GLY 110.A O no hydrogen 3.352 N/A CYS 115.A N LEU 101.A O no hydrogen 3.015 N/A ALA 116.A N MET 65.A O no hydrogen 2.959 N/A ILE 117.A N ILE 99.A O no hydrogen 2.712 N/A GLY 118.A N LEU 67.A O no hydrogen 2.901 N/A ASN 120.A N VAL 69.A O no hydrogen 2.767 N/A ALA 124.A N ASN 121.A OD1 no hydrogen 3.265 N/A HIS 126.A N ARG 122.A O no hydrogen 3.070 N/A ASN 127.A N LEU 123.A O no hydrogen 2.857 N/A THR 128.A N ALA 124.A O no hydrogen 3.025 N/A THR 128.A OG1 ALA 124.A O no hydrogen 2.797 N/A LEU 129.A N ILE 125.A O no hydrogen 3.013 N/A LEU 130.A N HIS 126.A O no hydrogen 2.988 N/A LEU 131.A N ASN 127.A O no hydrogen 2.992 N/A SER 132.A N THR 128.A O no hydrogen 2.768 N/A SER 132.A OG GLU 55.A O no hydrogen 3.554 N/A SER 132.A OG THR 128.A O no hydrogen 2.848 N/A SER 133.A N LEU 129.A O no hydrogen 3.011 N/A SER 133.A OG LEU 129.A O no hydrogen 3.183 N/A TYR 134.A N LEU 130.A O no hydrogen 3.122 N/A TYR 134.A OH PRO 188.A O no hydrogen 2.843 N/A THR 135.A N LEU 131.A O no hydrogen 3.025 N/A THR 135.A OG1.A SER 56.A O no hydrogen 3.227 N/A THR 135.A OG1.A SER 132.A O no hydrogen 2.726 N/A LYS 136.A N SER 132.A O no hydrogen 3.153 N/A LEU 137.A N SER 133.A O no hydrogen 3.032 N/A LEU 137.A N TYR 134.A O no hydrogen 3.070 N/A ASP 138.A N TYR 134.A O no hydrogen 3.359 N/A ARG 140.A N ASP 138.A OD2 no hydrogen 2.866 N/A ARG 140.A NE ASP 138.A OD2 no hydrogen 2.899 N/A ARG 140.A NH1 ASN 220.A O no hydrogen 3.172 N/A ARG 140.A NH1 ASN 220.A OD1 no hydrogen 3.212 N/A ARG 140.A NH1 SER 222.A O no hydrogen 2.711 N/A ARG 140.A NH2 ASP 138.A OD1 no hydrogen 2.982 N/A ARG 140.A NH2 ASN 220.A O no hydrogen 2.884 N/A LEU 141.A N ASP 138.A O no hydrogen 3.187 N/A LYS 142.A NZ TYR 15.A OH no hydrogen 3.306 N/A MET 144.A N ARG 140.A O no hydrogen 3.220 N/A VAL 145.A N LEU 141.A O no hydrogen 2.909 N/A LEU 146.A N LYS 142.A O no hydrogen 3.012 N/A LEU 147.A N PRO 143.A O no hydrogen 3.005 N/A VAL 148.A N MET 144.A O no hydrogen 2.999 N/A LYS 149.A N VAL 145.A O no hydrogen 2.917 N/A LYS 149.A NZ LEU 58.A O no hydrogen 2.737 N/A HIS 150.A N LEU 146.A O no hydrogen 2.893 N/A TRP 151.A N LEU 147.A O no hydrogen 2.932 N/A ALA 152.A N VAL 148.A O no hydrogen 2.847 N/A LYS 153.A N LYS 149.A O no hydrogen 2.945 N/A LYS 153.A NZ ASN 158.A OD1 no hydrogen 2.602 N/A ARG 154.A N HIS 150.A O no hydrogen 2.942 N/A ARG 154.A NE PHE 316.A O no hydrogen 3.014 N/A LYS 155.A N TRP 151.A O no hydrogen 2.932 N/A LYS 155.A NZ SER 314.A O no hydrogen 2.843 N/A LYS 155.A NZ GLU 317.A O no hydrogen 2.653 N/A GLN 156.A N LYS 153.A O no hydrogen 3.206 N/A ILE 157.A N ALA 152.A O no hydrogen 3.018 N/A ASN 158.A ND2 LEU 165.A O no hydrogen 2.979 N/A ASN 158.A ND2 SER 167.A OG no hydrogen 3.121 N/A SER 159.A N THR 164.A OG1 no hydrogen 2.944 N/A PHE 162.A N SER 159.A O no hydrogen 2.983 N/A GLY 163.A N PRO 160.A O no hydrogen 3.309 N/A THR 164.A N SER 159.A O no hydrogen 2.849 N/A THR 164.A OG1 SER 159.A O no hydrogen 3.334 N/A LEU 165.A N ILE 157.A O no hydrogen 3.337 N/A SER 167.A OG ASN 158.A OD1 no hydrogen 3.338 N/A TYR 168.A OH ASP 272.A OD1 no hydrogen 2.682 N/A GLY 169.A N SER 166.A OG no hydrogen 3.083 N/A TYR 170.A N SER 166.A O no hydrogen 3.153 N/A TYR 170.A OH ILE 157.A O no hydrogen 2.704 N/A VAL 171.A N SER 167.A O no hydrogen 3.007 N/A LEU 172.A N TYR 168.A O no hydrogen 3.033 N/A MET 173.A N GLY 169.A O no hydrogen 3.050 N/A VAL 174.A N TYR 170.A O no hydrogen 2.895 N/A LEU 175.A N VAL 171.A O no hydrogen 2.859 N/A TYR 176.A N LEU 172.A O no hydrogen 2.824 N/A TYR 176.A OH GLY 253.A O no hydrogen 2.601 N/A TYR 177.A N MET 173.A O no hydrogen 3.147 N/A LEU 178.A N VAL 174.A O no hydrogen 3.019 N/A ILE 179.A N LEU 175.A O no hydrogen 2.899 N/A HIS 180.A N TYR 176.A O no hydrogen 2.862 N/A VAL 181.A N TYR 177.A O no hydrogen 3.177 N/A ILE 182.A N TYR 177.A O no hydrogen 3.027 N/A VAL 186.A N LEU 178.A O no hydrogen 2.929 N/A ASN 189.A ND2 HIS 180.A NE2 no hydrogen 3.002 N/A ASN 189.A ND2 PHE 248.A O no hydrogen 2.965 N/A LEU 190.A N TYR 134.A OH no hydrogen 2.997 N/A LEU 191.A N ASN 189.A OD1 no hydrogen 2.855 N/A LEU 192.A N ASN 189.A O no hydrogen 3.270 N/A LEU 192.A N ASN 189.A OD1 no hydrogen 3.058 N/A SER 193.A OG ASP 209.A OD2 no hydrogen 2.746 N/A LEU 195.A N SER 193.A OG no hydrogen 3.006 N/A LYS 196.A N SER 193.A O no hydrogen 3.086 N/A LYS 196.A NZ ASP 205.A OD2 no hydrogen 2.588 N/A LYS 199.A N ASP 205.A OD1 no hydrogen 2.941 N/A VAL 201.A N PHE 204.A O no hydrogen 2.806 N/A PHE 204.A N VAL 201.A O no hydrogen 3.015 N/A VAL 206.A N LYS 199.A O no hydrogen 2.763 N/A GLY 207.A N ASP 205.A OD1 no hydrogen 3.013 N/A ASP 209.A N LEU 190.A O no hydrogen 2.804 N/A LYS 211.A NZ GLU 213.A OE2 no hydrogen 3.166 N/A LYS 211.A NZ ASP 214.A OD2 no hydrogen 3.343 N/A GLU 213.A N GLU 213.A OE1 no hydrogen 2.618 N/A ASP 214.A N LYS 211.A O no hydrogen 3.189 N/A ILE 215.A N LEU 212.A O no hydrogen 3.027 N/A SER 218.A OG PRO 185.A O no hydrogen 3.509 N/A SER 218.A OG VAL 186.A O no hydrogen 2.762 N/A SER 218.A OG ASN 220.A O no hydrogen 3.569 N/A ASN 220.A N SER 218.A OG no hydrogen 3.096 N/A ASN 220.A ND2 PRO 184.A O no hydrogen 2.841 N/A SER 222.A N ASN 220.A OD1 no hydrogen 2.847 N/A SER 222.A OG ASN 220.A OD1 no hydrogen 3.132 N/A SER 223.A N ASP 1.A OD2 no hydrogen 2.812 N/A SER 223.A OG ASP 1.A OD2 no hydrogen 3.257 N/A SER 223.A OG THR 8.A OG1 no hydrogen 3.194 N/A SER 223.A OG SER 226.A OG no hydrogen 3.214 N/A GLY 225.A N THR 8.A OG1 no hydrogen 2.863 N/A SER 226.A N SER 223.A OG no hydrogen 3.100 N/A SER 226.A OG ASP 1.A OD1 no hydrogen 3.473 N/A SER 226.A OG ASP 1.A OD2 no hydrogen 2.675 N/A SER 226.A OG SER 3.A OG no hydrogen 2.898 N/A SER 226.A OG HIS 4.A ND1 no hydrogen 2.818 N/A SER 226.A OG SER 223.A OG no hydrogen 3.214 N/A LEU 227.A N SER 223.A O no hydrogen 2.994 N/A LEU 228.A N LEU 224.A O no hydrogen 2.995 N/A HIS 229.A N GLY 225.A O no hydrogen 3.072 N/A HIS 229.A ND1 HIS 4.A NE2 no hydrogen 2.823 N/A HIS 229.A NE2 ASN 304.A OD1 no hydrogen 2.863 N/A GLY 230.A N SER 226.A O no hydrogen 3.038 N/A PHE 231.A N LEU 227.A O no hydrogen 2.903 N/A PHE 232.A N LEU 228.A O no hydrogen 2.950 N/A ARG 233.A N HIS 229.A O no hydrogen 3.037 N/A ARG 233.A NH1 ASN 304.A OD1 no hydrogen 2.853 N/A PHE 234.A N GLY 230.A O no hydrogen 2.971 N/A TYR 235.A N PHE 231.A O no hydrogen 3.309 N/A TYR 235.A OH MET 173.A O no hydrogen 2.706 N/A ALA 236.A N PHE 232.A O no hydrogen 2.940 N/A TYR 237.A N ARG 233.A O no hydrogen 2.987 N/A LYS 238.A N PHE 234.A O no hydrogen 2.969 N/A PHE 239.A N PHE 234.A O no hydrogen 2.825 N/A GLU 243.A N GLU 240.A O no hydrogen 3.133 N/A LYS 244.A N GLU 240.A O no hydrogen 2.848 N/A LYS 244.A NZ GLU 240.A OE2 no hydrogen 3.141 N/A VAL 245.A N LEU 255.A O no hydrogen 2.829 N/A VAL 246.A N ALA 269.A O no hydrogen 2.970 N/A THR 247.A OG1 GLU 271.A OE2 no hydrogen 2.854 N/A ARG 249.A N THR 247.A OG1 no hydrogen 2.947 N/A ARG 249.A NE PRO 273.A O no hydrogen 2.859 N/A ARG 249.A NH2 PRO 273.A O no hydrogen 2.938 N/A ARG 250.A NE GLU 259.A OE2 no hydrogen 3.460 N/A ARG 250.A NH1 ARG 249.A O no hydrogen 3.335 N/A ARG 250.A NH2 GLU 259.A OE2 no hydrogen 2.930 N/A GLY 253.A N ARG 250.A O no hydrogen 2.960 N/A TYR 254.A N ASP 252.A OD1 no hydrogen 2.878 N/A LYS 257.A N GLU 243.A O no hydrogen 2.898 N/A LYS 257.A NZ PRO 241.A O no hydrogen 2.981 N/A LYS 257.A NZ TYR 266.A O no hydrogen 2.589 N/A LYS 257.A NZ ILE 267.A O no hydrogen 3.083 N/A GLU 259.A N THR 256.A OG1 no hydrogen 3.117 N/A LYS 260.A N THR 256.A O no hydrogen 3.171 N/A LYS 260.A NZ GLU 271.A OE1 no hydrogen 2.531 N/A LYS 260.A NZ ILE 276.A O no hydrogen 2.755 N/A GLY 261.A N GLN 258.A O no hydrogen 3.001 N/A TRP 262.A N LYS 257.A O no hydrogen 2.818 N/A ARG 265.A NE ARG 282.A O no hydrogen 3.600 N/A ARG 265.A NH2 THR 283.A O no hydrogen 3.348 N/A ILE 270.A N ASN 279.A OD1 no hydrogen 2.709 N/A GLU 271.A N VAL 246.A O no hydrogen 2.926 N/A ASP 272.A N HIS 278.A O no hydrogen 3.227 N/A PHE 274.A N ASP 272.A OD2 no hydrogen 3.008 N/A GLU 275.A N ASP 272.A OD2 no hydrogen 2.831 N/A HIS 278.A N GLU 275.A O no hydrogen 2.885 N/A ASN 279.A ND2 ARG 265.A O no hydrogen 2.777 N/A ASN 279.A ND2 LEU 268.A O no hydrogen 3.111 N/A VAL 280.A N ILE 270.A O no hydrogen 2.845 N/A GLY 281.A N ASN 279.A OD1 no hydrogen 3.012 N/A ARG 282.A N ASN 279.A O no hydrogen 2.889 N/A THR 283.A OG1 THR 164.A O no hydrogen 2.731 N/A VAL 284.A N GLY 281.A O no hydrogen 2.998 N/A SER 285.A N GLY 163.A O no hydrogen 2.983 N/A SER 285.A OG GLY 163.A O no hydrogen 3.424 N/A SER 285.A OG SER 287.A OG no hydrogen 3.170 N/A SER 287.A OG SER 285.A OG no hydrogen 3.170 N/A GLY 288.A N SER 285.A OG no hydrogen 3.115 N/A LEU 289.A N SER 285.A O no hydrogen 2.937 N/A TYR 290.A N SER 286.A O no hydrogen 3.292 N/A ARG 291.A N SER 287.A O no hydrogen 3.084 N/A ARG 291.A NH1 GLN 156.A O no hydrogen 3.040 N/A ARG 291.A NH2 GLN 156.A O no hydrogen 3.239 N/A ILE 292.A N GLY 288.A O no hydrogen 2.828 N/A ARG 293.A N LEU 289.A O no hydrogen 2.698 N/A ARG 293.A NH2 TYR 235.A O no hydrogen 2.848 N/A ARG 293.A NH2 PHE 239.A O no hydrogen 2.903 N/A GLY 294.A N TYR 290.A O no hydrogen 2.946 N/A GLU 295.A N ARG 291.A O no hydrogen 3.041 N/A PHE 296.A N ILE 292.A O no hydrogen 3.082 N/A MET 297.A N ARG 293.A O no hydrogen 3.071 N/A ALA 298.A N GLY 294.A O no hydrogen 2.976 N/A ALA 299.A N GLU 295.A O no hydrogen 2.916 N/A SER 300.A N PHE 296.A O no hydrogen 3.003 N/A SER 300.A OG PHE 296.A O no hydrogen 2.913 N/A ARG 301.A N MET 297.A O no hydrogen 2.795 N/A LEU 302.A N ALA 298.A O no hydrogen 3.012 N/A LEU 303.A N ALA 299.A O no hydrogen 3.154 N/A ASN 304.A N SER 300.A O no hydrogen 2.906 N/A ASN 304.A N ARG 301.A O no hydrogen 3.285 N/A SER 305.A N LEU 302.A O no hydrogen 3.311 N/A SER 307.A N SER 305.A OG no hydrogen 3.375 N/A SER 307.A OG SER 305.A OG no hydrogen 3.250 N/A SER 314.A N PRO 311.A O no hydrogen 3.192 N/A SER 314.A OG PRO 311.A O no hydrogen 2.945 N/A LEU 315.A N TYR 312.A O no hydrogen 2.887 N/A PHE 316.A N ASP 313.A O no hydrogen 3.018 N/A GLU 317.A N SER 314.A O no hydrogen 3.234 N/A ALA 319.A N ARG 154.A O no hydrogen 3.082 N/A