Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4nmi_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 4.A N ASP 2.A OD1 no hydrogen 2.956 N/A TYR 4.A OH ASP 19.A OD2 no hydrogen 2.684 N/A SER 6.A OG GLU 149.A OE2 no hydrogen 2.629 N/A ARG 7.A N CYS 192.A O no hydrogen 2.790 N/A ARG 7.A NE GLU 149.A OE2 no hydrogen 2.871 N/A ARG 7.A NH1 GLU 154.A OE2 no hydrogen 2.883 N/A ARG 7.A NH2 GLU 149.A OE1 no hydrogen 2.872 N/A ARG 7.A NH2 GLU 154.A OE2 no hydrogen 3.114 N/A GLN 11.A N ASN 9.A OD1 no hydrogen 2.912 N/A LEU 15.A N PHE 189.A O no hydrogen 2.749 N/A ARG 17.A N ASN 187.A O no hydrogen 3.198 N/A ARG 17.A NE ASP 19.A O no hydrogen 2.917 N/A ARG 17.A NE PRO 20.A O no hydrogen 3.321 N/A ARG 17.A NH1 HIS 186.A O no hydrogen 2.917 N/A ARG 17.A NH1 GLU 227.A OE1 no hydrogen 2.776 N/A ARG 17.A NH2 PRO 20.A O no hydrogen 2.772 N/A ARG 17.A NH2 GLU 227.A OE2 no hydrogen 3.011 N/A LYS 18.A N TYR 4.A OH no hydrogen 2.920 N/A TYR 23.A N LEU 119.A O no hydrogen 2.840 N/A TYR 23.A OH MET 160.A O no hydrogen 2.718 N/A THR 24.A OG1 HIS 118.A O no hydrogen 2.612 N/A ARG 26.A NE ASP 29.A OD1 no hydrogen 2.861 N/A ARG 26.A NH1 ASP 40.A OD1 no hydrogen 2.900 N/A ARG 26.A NH1 GLU 43.A OE2 no hydrogen 3.019 N/A ARG 26.A NH2 ASP 29.A OD2 no hydrogen 2.866 N/A ARG 26.A NH2 ASP 40.A OD1 no hydrogen 2.884 N/A LYS 28.A N ASP 25.A O no hydrogen 2.813 N/A ASP 29.A N ARG 26.A O no hydrogen 3.157 N/A GLN 31.A N LYS 28.A O no hydrogen 2.917 N/A ALA 32.A N ASP 29.A O no hydrogen 3.003 N/A THR 35.A N GLN 38.A OE1 no hydrogen 2.942 N/A THR 35.A OG1 GLN 38.A OE1 no hydrogen 3.454 N/A LYS 36.A NZ ASP 40.A OD2 no hydrogen 2.736 N/A GLN 38.A N THR 35.A OG1 no hydrogen 3.028 N/A LEU 39.A N THR 35.A O no hydrogen 2.855 N/A ASP 40.A N LYS 36.A O no hydrogen 2.791 N/A SER 41.A N GLU 37.A O no hydrogen 2.980 N/A TYR 42.A N GLN 38.A O no hydrogen 2.981 N/A GLU 43.A N LEU 39.A O no hydrogen 2.919 N/A LYS 44.A N ASP 40.A O no hydrogen 2.915 N/A ASN 45.A N SER 41.A O no hydrogen 2.877 N/A ASN 45.A ND2 SER 41.A OG no hydrogen 3.338 N/A GLY 46.A N TYR 42.A O no hydrogen 2.835 N/A LEU 48.A N LEU 225.A O no hydrogen 2.844 N/A GLN 49.A NE2 THR 217.A O no hydrogen 2.880 N/A ILE 50.A N VAL 223.A O no hydrogen 2.755 N/A SER 55.A N GLU 58.A OE1 no hydrogen 2.841 N/A SER 55.A OG ASP 57.A OD1 no hydrogen 2.454 N/A VAL 59.A N SER 55.A O no hydrogen 3.045 N/A ILE 60.A N GLU 56.A O no hydrogen 3.175 N/A ASP 61.A N ASP 57.A O no hydrogen 2.914 N/A MET 62.A N GLU 58.A O no hydrogen 2.982 N/A GLN 63.A N VAL 59.A O no hydrogen 2.948 N/A GLN 63.A NE2 LEU 169.A O no hydrogen 2.927 N/A LYS 64.A N ILE 60.A O no hydrogen 2.908 N/A ALA 65.A N ASP 61.A O no hydrogen 2.855 N/A ILE 66.A N MET 62.A O no hydrogen 3.035 N/A PHE 67.A N GLN 63.A O no hydrogen 3.481 N/A GLU 68.A N LYS 64.A O no hydrogen 2.798 N/A LEU 69.A N ALA 65.A O no hydrogen 2.941 N/A GLN 70.A N ILE 66.A O no hydrogen 2.974 N/A GLN 70.A NE2 ILE 90.A O no hydrogen 3.229 N/A ASP 71.A N PHE 67.A O no hydrogen 3.050 N/A SER 72.A N GLU 68.A O no hydrogen 2.992 N/A SER 72.A OG GLU 68.A O no hydrogen 3.019 N/A ILE 73.A N LEU 69.A O no hydrogen 3.035 N/A LYS 74.A N ASP 71.A O no hydrogen 3.229 N/A LYS 74.A NZ ASP 71.A OD1 no hydrogen 2.874 N/A VAL 76.A N ILE 73.A O no hydrogen 3.037 N/A LYS 80.A N SER 78.A OG no hydrogen 3.180 N/A VAL 81.A N SER 78.A O no hydrogen 3.108 N/A ILE 82.A N SER 92.A O no hydrogen 2.847 N/A ARG 83.A NH1 LYS 74.A O no hydrogen 3.511 N/A ARG 83.A NH1 ASN 88.A O no hydrogen 3.112 N/A ARG 83.A NH2 ILE 73.A O no hydrogen 3.225 N/A ARG 83.A NH2 LYS 74.A O no hydrogen 3.171 N/A ARG 83.A NH2 VAL 76.A O no hydrogen 2.801 N/A GLU 84.A N ASP 89.A O no hydrogen 2.811 N/A GLU 86.A N GLU 86.A OE1 no hydrogen 2.305 N/A SER 87.A OG GLU 84.A OE1 no hydrogen 2.635 N/A ASN 88.A N GLU 84.A O no hydrogen 2.774 N/A ASP 89.A N SER 87.A OG no hydrogen 3.188 N/A ARG 91.A N ILE 82.A O no hydrogen 2.768 N/A ARG 91.A NE TYR 133.A O no hydrogen 3.003 N/A ARG 91.A NH1 GLU 84.A OE2 no hydrogen 2.537 N/A SER 92.A N ILE 82.A O no hydrogen 3.293 N/A ILE 93.A N ILE 131.A O no hydrogen 2.920 N/A PHE 94.A N LYS 80.A O no hydrogen 2.866 N/A HIS 95.A N SER 129.A O no hydrogen 2.950 N/A HIS 95.A ND1 ASP 99.A OD1 no hydrogen 3.314 N/A HIS 97.A N SER 129.A OG no hydrogen 3.018 N/A HIS 97.A ND1 SER 129.A OG no hydrogen 2.680 N/A GLN 98.A N HIS 95.A O no hydrogen 3.264 N/A GLN 98.A NE2 GLU 275.A OE1 no hydrogen 3.233 N/A ASP 99.A N HIS 95.A O no hydrogen 3.170 N/A ASP 100.A N VAL 96.A O no hydrogen 3.215 N/A TYR 102.A N ASP 100.A OD2 no hydrogen 3.072 N/A PHE 103.A N ASP 100.A OD2 no hydrogen 3.296 N/A GLN 104.A N ASP 100.A O no hydrogen 2.952 N/A ASP 105.A N ASN 101.A O no hydrogen 3.096 N/A VAL 106.A N TYR 102.A O no hydrogen 3.083 N/A ALA 107.A N PHE 103.A O no hydrogen 2.911 N/A ASN 108.A N GLN 104.A O no hydrogen 2.959 N/A ASP 109.A N VAL 106.A O no hydrogen 2.994 N/A LYS 110.A NZ ASP 114.A OD1 no hydrogen 3.071 N/A LYS 110.A NZ ASP 114.A OD2 no hydrogen 3.096 N/A ARG 111.A N ASP 109.A OD1 no hydrogen 2.967 N/A ARG 111.A NE ASP 109.A OD1 no hydrogen 2.786 N/A ARG 111.A NH1 GLU 58.A OE1 no hydrogen 2.981 N/A ARG 111.A NH2 GLU 58.A OE1 no hydrogen 3.493 N/A ARG 111.A NH2 GLU 58.A OE2 no hydrogen 3.054 N/A ARG 111.A NH2 ASP 109.A OD2 no hydrogen 2.711 N/A ILE 112.A N ASP 109.A O no hydrogen 2.953 N/A LEU 113.A N ASP 109.A O no hydrogen 2.976 N/A ASP 114.A N LYS 110.A O no hydrogen 2.857 N/A VAL 116.A N ILE 112.A O no hydrogen 3.070 N/A ARG 117.A N LEU 113.A O no hydrogen 2.908 N/A HIS 118.A N ASP 114.A O no hydrogen 3.260 N/A LEU 119.A N ILE 115.A O no hydrogen 2.907 N/A LEU 120.A N VAL 116.A O no hydrogen 2.906 N/A SER 122.A N ARG 117.A O no hydrogen 3.379 N/A SER 122.A OG ASP 123.A O no hydrogen 2.706 N/A SER 122.A OG SER 252.A OG no hydrogen 2.675 N/A TYR 125.A N ASN 251.A O no hydrogen 2.910 N/A HIS 127.A N VAL 249.A O no hydrogen 2.739 N/A SER 129.A OG HIS 97.A ND1 no hydrogen 2.680 N/A ARG 130.A N PHE 247.A O no hydrogen 2.813 N/A ARG 130.A NH2 SER 92.A OG no hydrogen 3.060 N/A ILE 131.A N ILE 93.A O no hydrogen 2.860 N/A ASN 132.A N ASN 245.A O no hydrogen 2.875 N/A ASN 132.A ND2 SER 92.A OG no hydrogen 2.830 N/A TYR 133.A N ARG 91.A O no hydrogen 2.863 N/A TYR 133.A OH ILE 66.A O no hydrogen 2.613 N/A LYS 134.A N ASN 244.A OD1 no hydrogen 2.873 N/A PHE 137.A N THR 239.A O no hydrogen 2.791 N/A LYS 138.A N PRO 135.A O no hydrogen 3.028 N/A PHE 142.A N SER 234.A O no hydrogen 2.797 N/A HIS 145.A N HIS 232.A O no hydrogen 2.897 N/A HIS 145.A ND1 ASP 143.A O no hydrogen 2.742 N/A SER 146.A OG ASN 229.A OD1 no hydrogen 2.671 N/A PHE 148.A N SER 228.A O no hydrogen 2.905 N/A GLU 149.A N SER 146.A OG no hydrogen 3.304 N/A TRP 151.A N ASP 147.A O no hydrogen 2.864 N/A HIS 152.A N PHE 148.A O no hydrogen 2.750 N/A HIS 152.A ND1 MET 157.A O no hydrogen 2.730 N/A HIS 152.A NE2 ASP 2.A OD1 no hydrogen 2.574 N/A VAL 153.A N GLU 149.A O no hydrogen 2.983 N/A GLU 154.A N THR 150.A O no hydrogen 2.737 N/A ASP 155.A N TRP 151.A O no hydrogen 3.045 N/A GLY 156.A N HIS 152.A O no hydrogen 3.139 N/A MET 157.A N TRP 151.A O no hydrogen 2.951 N/A ARG 159.A N ASN 255.A OD1 no hydrogen 3.068 N/A ARG 159.A NH1 ASP 19.A OD1 no hydrogen 2.843 N/A MET 160.A N ASP 19.A OD2 no hydrogen 2.927 N/A ARG 161.A NH1 LEU 120.A O no hydrogen 2.766 N/A ILE 163.A N TYR 250.A O no hydrogen 2.937 N/A SER 164.A N PHE 226.A O no hydrogen 2.862 N/A SER 164.A OG ASP 147.A OD2 no hydrogen 3.543 N/A VAL 165.A N MET 248.A O no hydrogen 2.727 N/A SER 166.A N THR 224.A O no hydrogen 2.860 N/A ILE 167.A N LEU 246.A O no hydrogen 2.814 N/A ALA 168.A N SER 222.A O no hydrogen 3.056 N/A LEU 169.A N ASN 244.A O no hydrogen 2.835 N/A ASN 172.A N GLY 218.A O no hydrogen 2.757 N/A TYR 173.A N ASN 176.A OD1 no hydrogen 3.300 N/A ASN 176.A ND2 TYR 241.A O no hydrogen 3.065 N/A MET 180.A N GLY 233.A O no hydrogen 2.829 N/A LEU 181.A N SER 214.A O no hydrogen 2.911 N/A ILE 182.A N MET 231.A O no hydrogen 3.056 N/A GLY 184.A N ASN 45.A O no hydrogen 2.910 N/A SER 185.A N ILE 182.A O no hydrogen 3.196 N/A SER 185.A OG ILE 182.A O no hydrogen 2.640 N/A HIS 186.A NE2 GLU 43.A O no hydrogen 2.937 N/A ASN 187.A N GLY 184.A O no hydrogen 3.266 N/A TYR 188.A N SER 185.A O no hydrogen 3.079 N/A PHE 189.A N LEU 15.A O no hydrogen 2.730 N/A SER 191.A N LYS 13.A O no hydrogen 2.859 N/A SER 191.A OG PRO 5.A O no hydrogen 3.117 N/A SER 191.A OG LYS 13.A O no hydrogen 3.441 N/A CYS 192.A N SER 6.A OG no hydrogen 2.843 N/A CYS 192.A SG VAL 190.A O no hydrogen 3.618 N/A GLY 194.A N ASN 9.A O no hydrogen 2.714 N/A SER 202.A N ASP 199.A OD2 no hydrogen 2.988 N/A SER 202.A OG ASP 199.A OD1 no hydrogen 2.621 N/A SER 202.A OG ASP 199.A OD2 no hydrogen 3.323 N/A LEU 203.A N ASP 199.A O no hydrogen 3.066 N/A ARG 204.A N GLU 200.A O no hydrogen 2.803 N/A GLU 205.A N GLU 201.A O no hydrogen 3.040 N/A LEU 206.A N SER 202.A O no hydrogen 2.951 N/A THR 207.A N LEU 203.A O no hydrogen 2.980 N/A THR 207.A OG1 LEU 203.A O no hydrogen 2.883 N/A ARG 208.A N ARG 204.A O no hydrogen 2.922 N/A ILE 209.A N GLU 205.A O no hydrogen 2.978 N/A GLY 210.A N LEU 206.A O no hydrogen 2.822 N/A GLY 211.A N THR 207.A O no hydrogen 2.922 N/A GLY 212.A N THR 207.A O no hydrogen 3.191 N/A SER 214.A N LEU 181.A O no hydrogen 2.831 N/A GLY 218.A N ASN 172.A O no hydrogen 2.967 N/A ALA 220.A N ASP 171.A OD1 no hydrogen 2.865 N/A GLY 221.A N ALA 168.A O no hydrogen 2.647 N/A SER 222.A N LYS 219.A O no hydrogen 3.047 N/A SER 222.A OG LYS 219.A O no hydrogen 2.753 N/A VAL 223.A N ILE 50.A O no hydrogen 2.965 N/A THR 224.A N SER 166.A O no hydrogen 2.889 N/A LEU 225.A N LEU 48.A O no hydrogen 2.843 N/A PHE 226.A N SER 164.A O no hydrogen 2.842 N/A GLU 227.A N GLY 46.A O no hydrogen 2.889 N/A SER 228.A N ALA 162.A O no hydrogen 3.030 N/A SER 228.A OG GLU 227.A OE1 no hydrogen 3.521 N/A SER 228.A OG GLU 227.A OE2 no hydrogen 2.820 N/A ASN 229.A N GLU 227.A OE1 no hydrogen 2.770 N/A ASN 229.A ND2 HIS 186.A O no hydrogen 3.138 N/A ASN 229.A ND2 TYR 188.A O no hydrogen 2.871 N/A THR 230.A N GLU 227.A O no hydrogen 3.070 N/A THR 230.A OG1 GLY 46.A O no hydrogen 2.726 N/A THR 230.A OG1 GLU 227.A O no hydrogen 3.450 N/A MET 231.A N SER 185.A OG no hydrogen 2.854 N/A HIS 232.A N HIS 145.A O no hydrogen 3.018 N/A HIS 232.A ND1 THR 230.A O no hydrogen 3.095 N/A GLY 233.A N MET 180.A O no hydrogen 2.990 N/A SER 234.A N PHE 142.A O no hydrogen 3.028 N/A THR 235.A OG1 SER 236.A O no hydrogen 3.038 N/A ASN 237.A ND2 TYR 241.A O no hydrogen 2.812 N/A THR 239.A N ASN 237.A OD1 no hydrogen 2.866 N/A THR 239.A OG1 ASN 237.A OD1 no hydrogen 2.713 N/A TYR 241.A N THR 239.A OG1 no hydrogen 3.216 N/A ARG 243.A N LYS 134.A O no hydrogen 2.920 N/A ARG 243.A NH1 GLY 177.A O no hydrogen 2.777 N/A ARG 243.A NH1 THR 235.A O no hydrogen 3.352 N/A ARG 243.A NH2 LYS 138.A O no hydrogen 2.976 N/A ARG 243.A NH2 GLY 139.A O no hydrogen 3.000 N/A ASN 244.A N SER 170.A OG no hydrogen 3.106 N/A ASN 245.A N ASN 132.A O no hydrogen 3.030 N/A ASN 245.A ND2 SER 166.A OG no hydrogen 3.246 N/A LEU 246.A N ILE 167.A O no hydrogen 3.079 N/A PHE 247.A N ARG 130.A O no hydrogen 2.854 N/A MET 248.A N VAL 165.A O no hydrogen 2.902 N/A VAL 249.A N GLN 128.A O no hydrogen 2.928 N/A TYR 250.A N ILE 163.A O no hydrogen 2.856 N/A TYR 250.A OH ALA 107.A O no hydrogen 2.653 N/A ASN 251.A N TYR 125.A O no hydrogen 2.851 N/A ASN 251.A ND2 TYR 125.A OH no hydrogen 2.890 N/A ASN 251.A ND2 ASN 255.A O no hydrogen 2.938 N/A SER 252.A N ARG 161.A O no hydrogen 3.183 N/A SER 252.A OG SER 122.A OG no hydrogen 2.675 N/A VAL 253.A N ASP 123.A O no hydrogen 3.060 N/A LYS 254.A N SER 252.A OG no hydrogen 2.972 N/A ASN 255.A N SER 252.A O no hydrogen 2.945 N/A ASN 255.A ND2 ARG 159.A O no hydrogen 2.918 N/A ASN 255.A ND2 ASN 251.A OD1 no hydrogen 2.916 N/A VAL 258.A N GLY 156.A O no hydrogen 2.905 N/A PHE 261.A N HIS 152.A O no hydrogen 3.339 N/A SER 262.A N VAL 153.A O no hydrogen 2.937 N/A SER 262.A OG VAL 153.A O no hydrogen 3.316 N/A GLY 263.A N PRO 260.A O no hydrogen 2.984 N/A GLY 264.A N SER 262.A OG no hydrogen 2.907 N/A ARG 267.A NE ASP 155.A OD1 no hydrogen 2.878 N/A ARG 267.A NH2 ASP 155.A OD2 no hydrogen 2.851 N/A ILE 271.A N PRO 268.A O no hydrogen 2.938 N/A ALA 272.A N PRO 268.A O no hydrogen 3.054 N/A VAL 273.A N HIS 127.A O no hydrogen 2.937 N/A ARG 274.A N GLU 269.A OE1 no hydrogen 2.762 N/A ARG 274.A N GLU 269.A OE2 no hydrogen 3.290 N/A ARG 274.A NH1 VAL 258.A O no hydrogen 2.897 N/A ARG 274.A NH2 VAL 258.A O no hydrogen 3.435 N/A GLU 275.A N GLU 269.A OE2 no hydrogen 3.054 N/A LYS 276.A NZ ARG 274.A O no hydrogen 3.091 N/A