Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4o0s_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 4.A N ASP 7.A OD2 no hydrogen 3.051 N/A ASP 7.A N ALA 4.A O no hydrogen 3.159 N/A PHE 8.A N LEU 5.A O no hydrogen 2.968 N/A GLU 9.A N ARG 26.A O no hydrogen 2.933 N/A GLY 11.A N LEU 24.A O no hydrogen 2.614 N/A ARG 12.A NH1 PRO 13.A O no hydrogen 3.162 N/A LEU 14.A N VAL 22.A O no hydrogen 2.589 N/A GLY 15.A N VAL 22.A O no hydrogen 3.046 N/A GLY 17.A N GLY 20.A O no hydrogen 2.454 N/A ASN 21.A N VAL 38.A O no hydrogen 3.299 N/A ASN 21.A ND2 TYR 23.A OH no hydrogen 3.459 N/A VAL 22.A N GLY 15.A O no hydrogen 2.628 N/A TYR 23.A N LEU 36.A O no hydrogen 2.621 N/A LEU 24.A N ARG 12.A O no hydrogen 3.043 N/A ALA 25.A N LEU 34.A O no hydrogen 2.773 N/A ARG 26.A N GLU 9.A O no hydrogen 2.930 N/A ARG 26.A NH2 GLU 9.A OE2 no hydrogen 2.303 N/A GLU 27.A N PHE 32.A O no hydrogen 2.702 N/A LYS 28.A N ASP 7.A O no hydrogen 2.863 N/A LYS 28.A NZ GLU 6.A O no hydrogen 2.798 N/A GLN 29.A N GLU 27.A OE2 no hydrogen 3.040 N/A SER 30.A N GLU 27.A OE1 no hydrogen 2.329 N/A SER 30.A OG GLU 27.A OE1 no hydrogen 2.681 N/A PHE 32.A N SER 30.A OG no hydrogen 3.133 N/A LEU 34.A N ALA 25.A O no hydrogen 2.879 N/A ALA 35.A N LEU 85.A O no hydrogen 2.793 N/A LEU 36.A N TYR 23.A O no hydrogen 2.553 N/A LYS 37.A N LEU 83.A O no hydrogen 2.984 N/A LYS 37.A NZ ASP 149.A OD1 no hydrogen 3.481 N/A VAL 38.A N ASN 21.A O no hydrogen 2.832 N/A LEU 39.A N VAL 81.A O no hydrogen 2.740 N/A GLN 43.A NE2 LYS 18.A O no hydrogen 2.435 N/A LEU 44.A N PHE 40.A O no hydrogen 3.369 N/A GLU 45.A N LYS 41.A O no hydrogen 2.817 N/A LEU 53.A N VAL 49.A O no hydrogen 2.566 N/A ARG 55.A N HIS 51.A O no hydrogen 3.115 N/A GLU 56.A N GLN 52.A O no hydrogen 3.022 N/A VAL 57.A N LEU 53.A O no hydrogen 2.918 N/A GLU 58.A N ARG 54.A O no hydrogen 3.127 N/A ILE 59.A N ARG 55.A O no hydrogen 3.161 N/A GLN 60.A N GLU 56.A O no hydrogen 3.148 N/A GLN 60.A NE2 LEU 69.A O no hydrogen 2.967 N/A SER 61.A N VAL 57.A O no hydrogen 3.112 N/A SER 61.A OG VAL 57.A O no hydrogen 2.059 N/A SER 61.A OG GLU 58.A O no hydrogen 3.089 N/A HIS 62.A N GLU 58.A O no hydrogen 3.390 N/A HIS 62.A ND1 GLU 58.A O no hydrogen 2.853 N/A LEU 63.A N GLN 60.A O no hydrogen 3.358 N/A ARG 64.A N TYR 121.A OH no hydrogen 3.111 N/A ASN 67.A N HIS 65.A ND1 no hydrogen 2.692 N/A ASN 67.A ND2 GLU 114.A OE1 no hydrogen 3.108 N/A ASN 67.A ND2 LEU 145.A O no hydrogen 3.064 N/A ILE 68.A N HIS 65.A O no hydrogen 3.320 N/A LEU 69.A N ILE 147.A O no hydrogen 2.768 N/A ARG 70.A N GLU 86.A OE2 no hydrogen 3.176 N/A TYR 72.A N ILE 84.A O no hydrogen 2.776 N/A GLY 73.A N ILE 84.A O no hydrogen 3.408 N/A PHE 75.A N TYR 82.A O no hydrogen 2.879 N/A ARG 80.A N ASP 77.A O no hydrogen 2.507 N/A ARG 80.A NE ASP 77.A OD1 no hydrogen 2.430 N/A ARG 80.A NH1 ASP 77.A OD1 no hydrogen 2.397 N/A VAL 81.A N LEU 39.A O no hydrogen 2.304 N/A TYR 82.A N PHE 75.A O no hydrogen 2.667 N/A LEU 83.A N LYS 37.A O no hydrogen 2.965 N/A ILE 84.A N GLY 73.A O no hydrogen 2.789 N/A LEU 85.A N ALA 35.A O no hydrogen 2.748 N/A GLU 86.A N ARG 70.A O no hydrogen 2.822 N/A LEU 90.A N LEU 139.A O no hydrogen 3.225 N/A GLY 91.A N ALA 88.A O no hydrogen 3.310 N/A VAL 93.A N LEU 137.A O no hydrogen 2.855 N/A TYR 94.A N PRO 134.A O no hydrogen 3.361 N/A ARG 95.A N THR 92.A OG1 no hydrogen 2.690 N/A ARG 95.A NH1 GLN 98.A OE1 no hydrogen 2.638 N/A GLU 96.A N THR 92.A O no hydrogen 3.188 N/A LEU 97.A N VAL 93.A O no hydrogen 2.754 N/A GLN 98.A N TYR 94.A O no hydrogen 3.184 N/A LYS 99.A N ARG 95.A O no hydrogen 3.181 N/A LEU 100.A N GLU 96.A O no hydrogen 2.955 N/A SER 101.A N LEU 97.A O no hydrogen 2.719 N/A PHE 103.A N PHE 196.A O no hydrogen 2.637 N/A ARG 107.A N ASP 104.A OD1 no hydrogen 2.515 N/A THR 108.A N ASP 104.A O no hydrogen 2.835 N/A THR 108.A OG1 ASP 104.A O no hydrogen 2.946 N/A ALA 109.A N GLU 105.A O no hydrogen 2.882 N/A THR 110.A N GLN 106.A O no hydrogen 3.277 N/A THR 110.A OG1 GLN 106.A O no hydrogen 2.616 N/A THR 110.A OG1 SER 262.A OG no hydrogen 3.369 N/A TYR 111.A N ARG 107.A O no hydrogen 3.184 N/A ILE 112.A N THR 108.A O no hydrogen 3.101 N/A THR 113.A N ALA 109.A O no hydrogen 3.002 N/A THR 113.A OG1 ALA 109.A O no hydrogen 3.066 N/A THR 113.A OG1 SER 261.A OG no hydrogen 3.040 N/A GLU 114.A N THR 110.A O no hydrogen 2.940 N/A LEU 115.A N TYR 111.A O no hydrogen 2.763 N/A ALA 116.A N ILE 112.A O no hydrogen 2.639 N/A ASN 117.A N THR 113.A O no hydrogen 2.873 N/A ALA 118.A N GLU 114.A O no hydrogen 3.036 N/A LEU 119.A N LEU 115.A O no hydrogen 2.814 N/A SER 120.A N ALA 116.A O no hydrogen 2.784 N/A SER 120.A OG ALA 116.A O no hydrogen 2.717 N/A TYR 121.A N ASN 117.A O no hydrogen 3.145 N/A CYS 122.A N ALA 118.A O no hydrogen 2.917 N/A CYS 122.A SG ALA 118.A O no hydrogen 3.387 N/A HIS 123.A N LEU 119.A O no hydrogen 2.688 N/A HIS 123.A NE2 ASP 185.A OD2 no hydrogen 2.661 N/A SER 124.A N SER 120.A O no hydrogen 2.833 N/A SER 124.A OG SER 120.A O no hydrogen 3.422 N/A SER 124.A OG TYR 121.A O no hydrogen 2.429 N/A LYS 125.A N TYR 121.A O no hydrogen 3.163 N/A LYS 125.A N CYS 122.A O no hydrogen 3.212 N/A ARG 126.A N HIS 123.A O no hydrogen 3.072 N/A VAL 127.A N CYS 122.A O no hydrogen 2.691 N/A ILE 128.A N VAL 154.A O no hydrogen 3.078 N/A HIS 129.A N ASP 185.A OD2 no hydrogen 3.378 N/A ARG 130.A N ASP 185.A OD1 no hydrogen 3.136 N/A ARG 130.A NE TRP 152.A O no hydrogen 2.741 N/A ARG 130.A NH1 TRP 152.A O no hydrogen 2.273 N/A LYS 133.A NZ ASP 131.A OD1 no hydrogen 3.366 N/A ASN 136.A N LYS 133.A O no hydrogen 2.750 N/A ASN 136.A ND2 ASP 131.A O no hydrogen 2.983 N/A ASN 136.A ND2 ASP 131.A OD2 no hydrogen 3.243 N/A LEU 137.A N PRO 134.A O no hydrogen 3.025 N/A LEU 138.A N LYS 146.A O no hydrogen 2.805 N/A LEU 139.A N GLY 91.A O no hydrogen 2.627 N/A GLY 140.A N GLU 144.A O no hydrogen 2.683 N/A GLY 143.A N GLY 140.A O no hydrogen 2.527 N/A GLU 144.A N GLU 144.A OE1 no hydrogen 2.433 N/A LEU 145.A N GLU 114.A OE2 no hydrogen 3.375 N/A LYS 146.A N LEU 138.A O no hydrogen 2.625 N/A LYS 146.A NZ PRO 66.A O no hydrogen 2.763 N/A LYS 146.A NZ GLU 86.A OE1 no hydrogen 3.148 N/A ILE 147.A N ASN 67.A O no hydrogen 2.715 N/A ALA 148.A N ASN 136.A O no hydrogen 3.077 N/A SER 153.A N PHE 150.A O no hydrogen 2.673 N/A SER 153.A OG PHE 150.A O no hydrogen 2.611 N/A VAL 154.A N ILE 128.A O no hydrogen 2.944 N/A SER 158.A N HIS 180.A O no hydrogen 3.166 N/A SER 158.A OG HIS 155.A O no hydrogen 2.466 N/A SER 158.A OG PRO 157.A O no hydrogen 3.321 N/A TYR 169.A OH GLU 195.A OE1 no hydrogen 3.321 N/A TYR 169.A OH GLU 195.A OE2 no hydrogen 2.660 N/A LEU 170.A N LEU 167.A O no hydrogen 2.948 N/A GLU 173.A N GLU 173.A OE1 no hydrogen 2.809 N/A ILE 175.A N PRO 171.A O no hydrogen 3.228 N/A GLU 176.A N PRO 172.A O no hydrogen 2.888 N/A GLY 177.A N MET 174.A O no hydrogen 3.165 N/A HIS 180.A N SER 158.A O no hydrogen 3.147 N/A LYS 183.A NZ ARG 245.A O no hydrogen 2.611 N/A VAL 184.A N ASP 181.A O no hydrogen 3.160 N/A ASP 185.A N GLU 182.A O no hydrogen 3.007 N/A TRP 187.A N LYS 183.A O no hydrogen 3.120 N/A SER 188.A N VAL 184.A O no hydrogen 3.203 N/A SER 188.A OG TYR 169.A O no hydrogen 3.538 N/A SER 188.A OG VAL 184.A O no hydrogen 3.471 N/A LEU 189.A N ASP 185.A O no hydrogen 2.960 N/A GLY 190.A N LEU 186.A O no hydrogen 3.165 N/A VAL 191.A N TRP 187.A O no hydrogen 2.945 N/A LEU 192.A N SER 188.A O no hydrogen 2.875 N/A CYS 193.A N LEU 189.A O no hydrogen 3.015 N/A TYR 194.A N GLY 190.A O no hydrogen 3.272 N/A TYR 194.A OH THR 221.A O no hydrogen 2.556 N/A GLU 195.A N VAL 191.A O no hydrogen 2.949 N/A PHE 196.A N LEU 192.A O no hydrogen 2.844 N/A LEU 197.A N CYS 193.A O no hydrogen 3.257 N/A VAL 198.A N TYR 194.A O no hydrogen 2.795 N/A GLY 199.A N GLU 195.A O no hydrogen 2.598 N/A GLU 204.A N PRO 201.A O no hydrogen 3.263 N/A GLN 209.A N GLN 209.A OE1 no hydrogen 2.962 N/A THR 211.A N THR 207.A O no hydrogen 2.886 N/A THR 211.A OG1 THR 207.A O no hydrogen 3.025 N/A TYR 212.A N TYR 208.A O no hydrogen 2.985 N/A LYS 213.A N GLN 209.A O no hydrogen 3.339 N/A ARG 214.A N GLU 210.A O no hydrogen 3.058 N/A ARG 214.A NE GLU 219.A O no hydrogen 3.226 N/A ARG 214.A NH2 GLU 204.A O no hydrogen 3.027 N/A ILE 215.A N THR 211.A O no hydrogen 2.885 N/A SER 216.A N TYR 212.A O no hydrogen 2.941 N/A SER 216.A OG GLU 176.A OE1 no hydrogen 2.775 N/A ARG 217.A N LYS 213.A O no hydrogen 2.699 N/A GLU 219.A N ARG 214.A O no hydrogen 2.994 N/A VAL 226.A N PRO 223.A O no hydrogen 3.253 N/A THR 227.A OG1 GLU 105.A OE1 no hydrogen 2.595 N/A ALA 230.A N THR 227.A OG1 no hydrogen 3.214 N/A ARG 231.A N THR 227.A O no hydrogen 2.832 N/A ARG 231.A NE VAL 226.A O no hydrogen 3.033 N/A ASP 232.A N GLU 228.A O no hydrogen 3.027 N/A LEU 233.A N GLY 229.A O no hydrogen 3.479 N/A ILE 234.A N ALA 230.A O no hydrogen 3.108 N/A SER 235.A N ARG 231.A O no hydrogen 2.881 N/A SER 235.A OG ARG 231.A O no hydrogen 3.023 N/A ARG 236.A N ASP 232.A O no hydrogen 3.152 N/A ARG 236.A NE ASP 232.A OD1 no hydrogen 2.834 N/A LEU 237.A N LEU 233.A O no hydrogen 3.008 N/A LEU 238.A N ILE 234.A O no hydrogen 2.767 N/A SER 243.A N ASN 241.A OD1 no hydrogen 3.029 N/A SER 243.A OG ASN 241.A OD1 no hydrogen 2.637 N/A GLN 244.A N ASN 241.A O no hydrogen 3.297 N/A ARG 245.A N PRO 242.A O no hydrogen 2.939 N/A ARG 245.A NE LYS 239.A O no hydrogen 2.866 N/A ARG 245.A NH1 GLU 173.A OE1 no hydrogen 2.754 N/A ARG 245.A NH1 LYS 239.A O no hydrogen 2.849 N/A ARG 245.A NH2 GLU 173.A OE2 no hydrogen 2.329 N/A ARG 245.A NH2 LYS 183.A O no hydrogen 3.375 N/A MET 247.A N GLU 250.A OE2 no hydrogen 3.179 N/A VAL 251.A N MET 247.A O no hydrogen 3.129 N/A LEU 252.A N LEU 248.A O no hydrogen 2.920 N/A GLU 253.A N ARG 249.A O no hydrogen 2.964 N/A HIS 254.A N VAL 251.A O no hydrogen 3.228 N/A HIS 254.A NE2 ASP 232.A OD1 no hydrogen 3.027 N/A TRP 256.A N HIS 254.A ND1 no hydrogen 3.045 N/A TRP 256.A NE1 GLU 105.A OE1 no hydrogen 2.605 N/A THR 258.A N HIS 254.A O no hydrogen 2.939 N/A THR 258.A OG1 HIS 254.A O no hydrogen 3.393 N/A ALA 259.A N PRO 255.A O no hydrogen 2.983 N/A ASN 260.A N TRP 256.A O no hydrogen 3.220 N/A ASN 260.A ND2 TRP 256.A O no hydrogen 2.703 N/A SER 261.A OG THR 113.A OG1 no hydrogen 3.040 N/A SER 261.A OG LYS 263.A O no hydrogen 2.984 N/A SER 262.A OG THR 110.A OG1 no hydrogen 3.369 N/A LYS 263.A NZ ASN 67.A OD1 no hydrogen 3.540 N/A SER 265.A OG LEU 252.A O no hydrogen 3.189 N/A