Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4o0t_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 4.A N GLU 1.A O no hydrogen 3.479 N/A LYS 6.A N GLU 2.A O no hydrogen 2.708 N/A LEU 7.A N ILE 3.A O no hydrogen 3.390 N/A ARG 8.A N LEU 4.A O no hydrogen 3.120 N/A SER 9.A N LYS 6.A O no hydrogen 3.451 N/A SER 9.A OG LYS 6.A O no hydrogen 2.767 N/A ILE 10.A N LEU 7.A O no hydrogen 3.243 N/A VAL 11.A N LEU 7.A O no hydrogen 3.352 N/A SER 12.A N SER 83.A O no hydrogen 2.696 N/A SER 12.A OG ASP 82.A OD1 no hydrogen 2.651 N/A SER 12.A OG ASP 82.A OD2 no hydrogen 3.358 N/A THR 21.A N MET 38.A O no hydrogen 2.549 N/A THR 21.A OG1 MET 38.A O no hydrogen 3.204 N/A GLU 24.A N THR 36.A O no hydrogen 3.106 N/A ILE 26.A N VAL 34.A O no hydrogen 2.811 N/A SER 31.A OG ASP 157.A OD1 no hydrogen 3.126 N/A SER 31.A OG ASP 157.A OD2 no hydrogen 2.692 N/A GLY 32.A N GLY 29.A O no hydrogen 3.363 N/A THR 33.A N GLN 50.A O no hydrogen 3.132 N/A VAL 34.A N GLY 27.A O no hydrogen 2.747 N/A TYR 35.A N ILE 48.A O no hydrogen 2.817 N/A THR 36.A N GLU 24.A O no hydrogen 2.909 N/A THR 36.A OG1 GLU 45.A OE1 no hydrogen 3.332 N/A ALA 37.A N VAL 46.A O no hydrogen 2.898 N/A MET 38.A N THR 21.A O no hydrogen 2.922 N/A VAL 40.A N LYS 19.A O no hydrogen 3.014 N/A VAL 46.A N ALA 37.A O no hydrogen 2.871 N/A ALA 47.A N MET 94.A O no hydrogen 2.914 N/A ILE 48.A N TYR 35.A O no hydrogen 2.818 N/A LYS 49.A N VAL 92.A O no hydrogen 3.090 N/A LYS 49.A NZ GLU 65.A OE1 no hydrogen 2.626 N/A LYS 49.A NZ GLU 65.A OE2 no hydrogen 3.399 N/A GLN 50.A N THR 33.A O no hydrogen 2.742 N/A MET 51.A N LEU 90.A O no hydrogen 2.878 N/A LEU 53.A N ASP 88.A O no hydrogen 2.949 N/A GLN 56.A N ASN 52.A O no hydrogen 3.021 N/A ASN 64.A N GLU 60.A O no hydrogen 3.398 N/A GLU 65.A N LEU 61.A O no hydrogen 3.062 N/A LEU 67.A N ILE 63.A O no hydrogen 3.083 N/A VAL 68.A N ASN 64.A O no hydrogen 3.146 N/A MET 69.A N GLU 65.A O no hydrogen 3.062 N/A ARG 70.A N ILE 66.A O no hydrogen 2.985 N/A ASN 72.A N MET 69.A O no hydrogen 3.047 N/A ASN 72.A ND2 VAL 68.A O no hydrogen 2.269 N/A LYS 73.A NZ TYR 80.A O no hydrogen 3.272 N/A ASN 74.A N ASN 79.A OD1 no hydrogen 3.313 N/A ASN 76.A N ASN 74.A OD1 no hydrogen 2.821 N/A ASN 76.A ND2 GLU 122.A OE1 no hydrogen 3.085 N/A ASN 76.A ND2 VAL 153.A O no hydrogen 2.911 N/A ILE 77.A N ASN 74.A O no hydrogen 3.056 N/A VAL 78.A N LEU 155.A O no hydrogen 3.070 N/A ASN 79.A N GLU 95.A OE2 no hydrogen 3.351 N/A ASN 79.A ND2 ASN 74.A O no hydrogen 3.453 N/A TYR 80.A OH SER 83.A OG no hydrogen 2.732 N/A LEU 81.A N VAL 93.A O no hydrogen 2.702 N/A ASP 82.A N VAL 93.A O no hydrogen 3.105 N/A SER 83.A N ASP 82.A OD1 no hydrogen 2.616 N/A SER 83.A OG TYR 80.A OH no hydrogen 2.732 N/A TYR 84.A N TRP 91.A O no hydrogen 3.017 N/A VAL 86.A N GLU 89.A O no hydrogen 2.973 N/A GLU 89.A N VAL 86.A O no hydrogen 2.922 N/A LEU 90.A N MET 51.A O no hydrogen 2.836 N/A TRP 91.A N TYR 84.A O no hydrogen 2.837 N/A TRP 91.A NE1 GLU 89.A OE1 no hydrogen 3.202 N/A VAL 92.A N LYS 49.A O no hydrogen 2.942 N/A VAL 93.A N ASP 82.A O no hydrogen 2.758 N/A MET 94.A N ALA 47.A O no hydrogen 2.920 N/A GLU 95.A N ASN 79.A O no hydrogen 3.023 N/A LEU 102.A N ILE 145.A O no hydrogen 3.037 N/A THR 103.A OG1 SER 142.A OG no hydrogen 2.583 N/A VAL 106.A N LEU 102.A O no hydrogen 2.857 N/A THR 107.A N THR 103.A O no hydrogen 3.133 N/A THR 107.A OG1 THR 103.A O no hydrogen 2.951 N/A THR 109.A N VAL 105.A O no hydrogen 3.061 N/A THR 109.A OG1 VAL 105.A O no hydrogen 2.788 N/A ASP 112.A N GLN 115.A OE1 no hydrogen 2.861 N/A GLN 115.A N ASP 112.A O no hydrogen 2.999 N/A GLN 115.A N ASP 112.A OD1 no hydrogen 2.844 N/A GLN 115.A NE2 SER 279.A O no hydrogen 2.918 N/A ILE 116.A N ASP 112.A O no hydrogen 3.014 N/A ALA 117.A N GLU 113.A O no hydrogen 3.005 N/A ALA 118.A N GLY 114.A O no hydrogen 3.260 N/A VAL 119.A N GLN 115.A O no hydrogen 3.198 N/A CYS 120.A N ILE 116.A O no hydrogen 2.952 N/A CYS 120.A SG ILE 116.A O no hydrogen 3.091 N/A ARG 121.A N ALA 117.A O no hydrogen 3.024 N/A ARG 121.A NH2 GLU 122.A OE2 no hydrogen 2.898 N/A GLU 122.A N ALA 118.A O no hydrogen 3.190 N/A CYS 123.A N VAL 119.A O no hydrogen 3.054 N/A CYS 123.A SG VAL 119.A O no hydrogen 3.252 N/A LEU 124.A N CYS 120.A O no hydrogen 2.953 N/A GLN 125.A N ARG 121.A O no hydrogen 3.058 N/A ALA 126.A N GLU 122.A O no hydrogen 3.285 N/A LEU 127.A N CYS 123.A O no hydrogen 2.979 N/A GLU 128.A N LEU 124.A O no hydrogen 2.770 N/A PHE 129.A N GLN 125.A O no hydrogen 3.150 N/A LEU 130.A N ALA 126.A O no hydrogen 2.947 N/A HIS 131.A N LEU 127.A O no hydrogen 2.769 N/A HIS 131.A NE2 ASP 196.A OD2 no hydrogen 2.835 N/A SER 132.A N GLU 128.A O no hydrogen 3.283 N/A SER 132.A OG GLU 128.A O no hydrogen 3.188 N/A SER 132.A OG PHE 129.A O no hydrogen 2.685 N/A ASN 133.A N LEU 130.A O no hydrogen 3.002 N/A ASN 133.A ND2 ASN 72.A OD1 no hydrogen 3.395 N/A GLN 134.A N HIS 131.A O no hydrogen 3.183 N/A VAL 135.A N LEU 130.A O no hydrogen 2.842 N/A ILE 136.A N ALA 162.A O no hydrogen 2.908 N/A HIS 137.A N ASP 196.A OD2 no hydrogen 2.944 N/A HIS 137.A NE2 THR 156.A O no hydrogen 2.935 N/A ARG 138.A N ASP 196.A OD1 no hydrogen 2.851 N/A ARG 138.A NE PHE 160.A O no hydrogen 2.743 N/A ARG 138.A NH1 GLU 173.A OE2 no hydrogen 3.448 N/A ARG 138.A NH1 TYR 191.A OH no hydrogen 3.162 N/A ARG 138.A NH2 PHE 160.A O no hydrogen 2.696 N/A ASN 139.A N HIS 137.A ND1 no hydrogen 2.991 N/A LYS 141.A NZ THR 177.A OG1 no hydrogen 3.077 N/A SER 142.A N GLU 206.A OE1 no hydrogen 3.162 N/A SER 142.A OG THR 103.A OG1 no hydrogen 2.583 N/A SER 142.A OG GLU 206.A OE1 no hydrogen 3.316 N/A SER 142.A OG GLU 206.A OE2 no hydrogen 2.579 N/A ASN 144.A N LYS 141.A O no hydrogen 2.720 N/A ASN 144.A ND2 ASN 139.A O no hydrogen 2.801 N/A ILE 145.A N SER 142.A O no hydrogen 3.147 N/A LEU 146.A N LYS 154.A O no hydrogen 2.824 N/A LEU 147.A N GLY 100.A O no hydrogen 3.187 N/A GLY 148.A N SER 152.A O no hydrogen 2.815 N/A GLY 151.A N GLY 148.A O no hydrogen 2.820 N/A SER 152.A OG ASP 150.A OD1 no hydrogen 2.571 N/A SER 152.A OG ASP 150.A OD2 no hydrogen 2.857 N/A LYS 154.A N LEU 146.A O no hydrogen 2.949 N/A LYS 154.A NZ PRO 75.A O no hydrogen 2.401 N/A LYS 154.A NZ ILE 77.A O no hydrogen 3.566 N/A LEU 155.A N ASN 76.A O no hydrogen 2.840 N/A THR 156.A N ASN 144.A O no hydrogen 2.871 N/A ASP 157.A N THR 156.A OG1 no hydrogen 2.684 N/A CYS 161.A N PHE 158.A O no hydrogen 3.195 N/A CYS 161.A SG ILE 136.A O no hydrogen 3.856 N/A ALA 162.A N ILE 136.A O no hydrogen 2.981 N/A ILE 164.A N GLN 134.A O no hydrogen 2.899 N/A GLN 168.A N THR 165.A O no hydrogen 2.808 N/A ARG 171.A N TYR 191.A O no hydrogen 2.964 N/A ARG 171.A NH1 GLU 173.A OE1 no hydrogen 3.114 N/A ARG 171.A NH2 GLN 163.A O no hydrogen 3.109 N/A THR 177.A OG1 ASN 139.A OD1 no hydrogen 2.811 N/A TRP 180.A N THR 177.A O no hydrogen 2.904 N/A TRP 180.A NE1 GLU 206.A OE1 no hydrogen 2.789 N/A MET 181.A N PRO 178.A O no hydrogen 3.031 N/A GLU 184.A N GLU 184.A OE2 no hydrogen 2.755 N/A VAL 185.A N ALA 182.A O no hydrogen 3.143 N/A VAL 186.A N ALA 182.A O no hydrogen 3.114 N/A THR 187.A N PRO 183.A O no hydrogen 2.903 N/A THR 187.A OG1 PRO 183.A O no hydrogen 3.045 N/A ARG 188.A N VAL 185.A O no hydrogen 3.326 N/A TYR 191.A N ARG 171.A O no hydrogen 2.990 N/A TYR 191.A OH GLU 173.A O no hydrogen 2.752 N/A LYS 194.A NZ VAL 256.A O no hydrogen 2.480 N/A LYS 194.A NZ ARG 259.A O no hydrogen 2.950 N/A VAL 195.A N GLY 192.A O no hydrogen 3.444 N/A ASP 196.A N PRO 193.A O no hydrogen 3.133 N/A TRP 198.A N LYS 194.A O no hydrogen 3.133 N/A SER 199.A N VAL 195.A O no hydrogen 3.196 N/A SER 199.A OG TRP 180.A O no hydrogen 2.657 N/A SER 199.A OG VAL 195.A O no hydrogen 3.055 N/A LEU 200.A N ASP 196.A O no hydrogen 2.964 N/A GLY 201.A N ILE 197.A O no hydrogen 3.085 N/A ILE 202.A N TRP 198.A O no hydrogen 2.971 N/A MET 203.A N SER 199.A O no hydrogen 2.972 N/A ALA 204.A N LEU 200.A O no hydrogen 2.956 N/A ILE 205.A N GLY 201.A O no hydrogen 3.183 N/A GLU 206.A N ILE 202.A O no hydrogen 3.085 N/A MET 207.A N MET 203.A O no hydrogen 3.079 N/A ILE 208.A N ALA 204.A O no hydrogen 2.844 N/A ILE 208.A N ILE 205.A O no hydrogen 3.139 N/A GLU 209.A N ILE 205.A O no hydrogen 2.607 N/A GLY 210.A N GLU 206.A O no hydrogen 2.576 N/A ASN 216.A ND2 GLU 217.A OE1 no hydrogen 3.079 N/A GLU 217.A N TYR 214.A O no hydrogen 2.932 N/A ALA 222.A N ASN 218.A O no hydrogen 2.667 N/A LEU 223.A N PRO 219.A O no hydrogen 3.018 N/A TYR 224.A N LEU 220.A O no hydrogen 3.017 N/A LEU 225.A N ARG 221.A O no hydrogen 2.810 N/A ILE 226.A N ALA 222.A O no hydrogen 2.724 N/A ALA 227.A N LEU 223.A O no hydrogen 2.941 N/A THR 228.A N TYR 224.A O no hydrogen 2.813 N/A THR 228.A OG1 TYR 224.A O no hydrogen 3.039 N/A THR 228.A OG1 LEU 225.A O no hydrogen 3.016 N/A THR 228.A OG1 ASN 229.A OD1 no hydrogen 3.264 N/A ASN 229.A N LEU 225.A O no hydrogen 2.655 N/A ASN 229.A ND2 TYR 214.A OH no hydrogen 2.866 N/A GLY 230.A N ILE 226.A O no hydrogen 3.143 N/A THR 231.A OG1 LEU 252.A O no hydrogen 2.839 N/A GLN 235.A N GLU 209.A OE2 no hydrogen 3.018 N/A GLN 235.A NE2 GLU 209.A OE1 no hydrogen 3.019 N/A ASN 236.A ND2 GLU 238.A OE1 no hydrogen 3.123 N/A LYS 239.A N ASN 236.A O no hydrogen 3.209 N/A LEU 240.A N PRO 237.A O no hydrogen 3.328 N/A SER 241.A N GLU 113.A OE2 no hydrogen 2.929 N/A SER 241.A OG GLU 113.A OE1 no hydrogen 2.657 N/A PHE 244.A N SER 241.A O no hydrogen 3.197 N/A PHE 244.A N SER 241.A OG no hydrogen 3.206 N/A ARG 245.A N SER 241.A O no hydrogen 3.097 N/A ARG 245.A NH1 PRO 237.A O no hydrogen 3.200 N/A ASP 246.A N ALA 242.A O no hydrogen 3.376 N/A LEU 248.A N PHE 244.A O no hydrogen 2.961 N/A ASN 249.A N ARG 245.A O no hydrogen 3.109 N/A ARG 250.A N PHE 247.A O no hydrogen 3.198 N/A ARG 250.A NH1 ASP 246.A OD1 no hydrogen 3.272 N/A CYS 251.A N LEU 248.A O no hydrogen 2.914 N/A CYS 251.A SG PHE 247.A O no hydrogen 3.515 N/A LEU 252.A N LEU 248.A O no hydrogen 2.866 N/A GLU 257.A N ASP 255.A OD2 no hydrogen 3.135 N/A ARG 259.A NE GLU 253.A O no hydrogen 2.941 N/A ARG 259.A NH1 GLU 184.A OE1 no hydrogen 2.387 N/A ARG 259.A NH1 LYS 194.A O no hydrogen 3.333 N/A ARG 259.A NH2 GLU 184.A OE2 no hydrogen 3.011 N/A ARG 259.A NH2 GLU 253.A O no hydrogen 3.115 N/A GLY 260.A N ARG 250.A O no hydrogen 2.915 N/A SER 261.A N GLU 264.A OE1 no hydrogen 2.959 N/A LEU 265.A N SER 261.A O no hydrogen 2.859 N/A LEU 266.A N ALA 262.A O no hydrogen 3.219 N/A GLN 267.A N GLU 264.A O no hydrogen 3.373 N/A HIS 268.A N LEU 265.A O no hydrogen 3.208 N/A HIS 268.A NE2 ASP 246.A OD1 no hydrogen 2.798 N/A PHE 270.A N HIS 268.A ND1 no hydrogen 2.996 N/A LEU 271.A N HIS 268.A O no hydrogen 3.339 N/A LYS 272.A N GLN 269.A O no hydrogen 3.085 N/A LYS 275.A N GLY 114.A O no hydrogen 3.078 N/A LYS 275.A NZ ASP 112.A OD2 no hydrogen 2.716 N/A SER 279.A N PRO 276.A O no hydrogen 2.933 N/A SER 279.A OG PRO 276.A O no hydrogen 2.734 N/A LEU 280.A N LEU 277.A O no hydrogen 3.094 N/A THR 281.A N SER 278.A O no hydrogen 3.338 N/A THR 281.A OG1 SER 278.A O no hydrogen 3.209 N/A ILE 284.A N LEU 280.A O no hydrogen 3.270 N/A ILE 284.A N THR 281.A O no hydrogen 3.063 N/A ALA 285.A N THR 281.A O no hydrogen 3.048 N/A ALA 286.A N PRO 282.A O no hydrogen 2.899 N/A ALA 287.A N LEU 283.A O no hydrogen 2.868 N/A LYS 288.A N ILE 284.A O no hydrogen 3.021 N/A GLU 289.A N ALA 285.A O no hydrogen 3.164 N/A GLU 289.A N ALA 286.A O no hydrogen 3.294 N/A ALA 290.A N ALA 286.A O no hydrogen 3.320 N/A THR 291.A N ALA 287.A O no hydrogen 3.179 N/A THR 291.A OG1 ALA 287.A O no hydrogen 3.280 N/A LYS 292.A N LYS 288.A O no hydrogen 3.283 N/A