Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4o1l_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 4.A N LYS 79.A O no hydrogen 2.851 N/A ASN 4.A ND2 THR 82.A OG1 no hydrogen 3.092 N/A ASN 4.A ND2 ASP 106.A OD2 no hydrogen 2.728 N/A LEU 6.A N ALA 80.A O no hydrogen 2.958 N/A PHE 7.A N VAL 161.A O no hydrogen 2.906 N/A GLY 8.A N THR 82.A O no hydrogen 2.748 N/A GLY 10.A N PHE 84.A O no hydrogen 3.212 N/A LEU 14.A N GLY 118.A O no hydrogen 3.046 N/A ASP 15.A N HIS 58.A O no hydrogen 2.746 N/A ILE 16.A N CYS 120.A O no hydrogen 2.967 N/A SER 17.A N GLU 56.A O no hydrogen 2.888 N/A ALA 18.A N ALA 122.A O no hydrogen 3.001 N/A VAL 20.A N ILE 124.A O no hydrogen 2.761 N/A LYS 22.A NZ ASP 26.A OD1 no hydrogen 3.376 N/A LYS 22.A NZ ASP 26.A OD2 no hydrogen 2.748 N/A PHE 24.A N ASP 21.A O no hydrogen 3.236 N/A PHE 24.A N ASP 21.A OD1 no hydrogen 3.372 N/A LEU 25.A N ASP 21.A O no hydrogen 3.330 N/A ASP 26.A N LYS 22.A O no hydrogen 2.847 N/A LYS 27.A N ASP 23.A O no hydrogen 2.785 N/A LYS 27.A NZ GLU 48.A OE1 no hydrogen 3.465 N/A LYS 27.A NZ GLU 48.A OE2 no hydrogen 3.500 N/A TYR 28.A N PHE 24.A O no hydrogen 3.141 N/A TYR 28.A OH GLU 48.A OE2 no hydrogen 2.395 N/A SER 29.A N ASP 26.A O no hydrogen 3.056 N/A LEU 30.A N LEU 25.A O no hydrogen 2.802 N/A ASN 33.A ND2 ASN 128.A OD1 no hydrogen 2.697 N/A ASP 34.A N ARG 129.A O no hydrogen 3.327 N/A GLN 35.A N ASP 34.A OD1 no hydrogen 2.921 N/A ILE 36.A N LEU 131.A O no hydrogen 2.918 N/A ALA 38.A N ALA 133.A O no hydrogen 2.680 N/A GLU 39.A N HIS 42.A ND1 no hydrogen 2.973 N/A HIS 42.A N GLU 39.A O no hydrogen 3.088 N/A LYS 43.A N ASP 40.A O no hydrogen 3.029 N/A LEU 45.A N HIS 42.A O no hydrogen 3.255 N/A GLU 48.A N GLU 44.A O no hydrogen 3.050 N/A LEU 49.A N LEU 45.A O no hydrogen 2.999 N/A VAL 50.A N PHE 46.A O no hydrogen 3.442 N/A LYS 51.A N ASP 47.A O no hydrogen 2.986 N/A LYS 52.A N GLU 48.A O no hydrogen 2.945 N/A PHE 53.A N LEU 49.A O no hydrogen 3.071 N/A GLU 56.A N SER 17.A O no hydrogen 2.830 N/A HIS 58.A N ASP 15.A O no hydrogen 2.992 N/A GLY 60.A N LEU 13.A O no hydrogen 2.636 N/A SER 62.A OG ASP 295.A OD1 no hydrogen 2.598 N/A THR 63.A OG1 MET 9.A O no hydrogen 3.448 N/A GLN 64.A NE2 GLY 60.A O no hydrogen 2.766 N/A ASN 65.A N GLY 61.A O no hydrogen 2.846 N/A ASN 65.A ND2 ASP 295.A OD2 no hydrogen 2.748 N/A SER 66.A N SER 62.A O no hydrogen 3.116 N/A SER 66.A OG ASP 295.A O no hydrogen 2.586 N/A ILE 67.A N THR 63.A O no hydrogen 2.909 N/A LYS 68.A N GLN 64.A O no hydrogen 3.135 N/A VAL 69.A N ASN 65.A O no hydrogen 3.025 N/A ALA 70.A N SER 66.A O no hydrogen 2.835 N/A GLN 71.A N ILE 67.A O no hydrogen 2.968 N/A GLN 71.A NE2 PRO 77.A O no hydrogen 2.905 N/A TRP 72.A N LYS 68.A O no hydrogen 2.967 N/A MET 73.A N VAL 69.A O no hydrogen 3.067 N/A ILE 74.A N ALA 70.A O no hydrogen 2.981 N/A GLN 75.A N GLN 71.A O no hydrogen 2.896 N/A GLN 75.A NE2 TRP 72.A O no hydrogen 2.572 N/A GLN 76.A N ILE 74.A O no hydrogen 2.780 N/A LYS 79.A N HIS 104.A O no hydrogen 2.857 N/A ALA 81.A N GLN 71.A OE1 no hydrogen 3.060 N/A THR 82.A N LEU 6.A O no hydrogen 2.720 N/A THR 82.A OG1 LEU 6.A O no hydrogen 3.431 N/A PHE 83.A N ASP 106.A O no hydrogen 3.257 N/A PHE 84.A N GLY 8.A O no hydrogen 2.903 N/A CYS 86.A SG ILE 87.A O no hydrogen 3.816 N/A CYS 86.A SG TYR 110.A O no hydrogen 3.318 N/A CYS 86.A SG ALA 137.A O no hydrogen 3.069 N/A ILE 87.A N TYR 110.A O no hydrogen 2.967 N/A GLY 88.A N THR 117.A OG1 no hydrogen 3.107 N/A GLY 93.A N ASP 90.A OD1 no hydrogen 2.692 N/A GLU 94.A N ASP 90.A O no hydrogen 3.003 N/A ILE 95.A N LYS 91.A O no hydrogen 3.058 N/A LEU 96.A N PHE 92.A O no hydrogen 3.157 N/A LYS 97.A N GLY 93.A O no hydrogen 3.020 N/A LYS 97.A NZ GLU 94.A OE1 no hydrogen 3.000 N/A LYS 97.A NZ GLU 111.A OE1 no hydrogen 2.310 N/A ARG 98.A N GLU 94.A O no hydrogen 2.968 N/A LYS 99.A N ILE 95.A O no hydrogen 2.871 N/A LYS 99.A NZ GLU 102.A OE2 no hydrogen 2.884 N/A ALA 100.A N LEU 96.A O no hydrogen 2.977 N/A ALA 101.A N LYS 97.A O no hydrogen 3.096 N/A GLU 102.A N ARG 98.A O no hydrogen 2.898 N/A ALA 103.A N LYS 99.A O no hydrogen 2.954 N/A HIS 104.A N ALA 101.A O no hydrogen 2.862 N/A VAL 105.A N ALA 100.A O no hydrogen 3.082 N/A ASP 106.A N ALA 81.A O no hydrogen 2.978 N/A HIS 108.A N PHE 83.A O no hydrogen 2.861 N/A HIS 108.A NE2 ASP 106.A OD1 no hydrogen 3.126 N/A TYR 109.A OH GLN 64.A OE1 no hydrogen 2.571 N/A TYR 110.A N GLY 85.A O no hydrogen 2.810 N/A GLN 112.A N ILE 87.A O no hydrogen 3.296 N/A GLN 112.A NE2 ILE 87.A O no hydrogen 2.999 N/A GLN 112.A NE2 GLN 115.A O no hydrogen 3.225 N/A GLN 115.A N GLN 112.A OE1 no hydrogen 3.140 N/A THR 117.A N ASP 90.A OD2 no hydrogen 2.856 N/A THR 117.A OG1 ASP 90.A OD1 no hydrogen 2.691 N/A THR 117.A OG1 ASP 90.A OD2 no hydrogen 3.391 N/A THR 119.A N ASN 134.A O no hydrogen 3.029 N/A CYS 120.A N LEU 14.A O no hydrogen 3.039 N/A CYS 120.A SG ILE 132.A O no hydrogen 3.958 N/A ALA 121.A N ILE 132.A O no hydrogen 2.880 N/A ALA 122.A N ILE 16.A O no hydrogen 2.939 N/A CYS 123.A N SER 130.A O no hydrogen 3.093 N/A CYS 123.A SG SER 130.A O no hydrogen 3.709 N/A ILE 124.A N ALA 18.A O no hydrogen 2.828 N/A THR 125.A N ASN 128.A O no hydrogen 3.111 N/A ASN 128.A N THR 125.A O no hydrogen 2.749 N/A ARG 129.A N ASN 33.A OD1 no hydrogen 3.394 N/A SER 130.A N CYS 123.A O no hydrogen 2.989 N/A SER 130.A OG LYS 31.A O no hydrogen 2.467 N/A LEU 131.A N ASP 34.A O no hydrogen 2.934 N/A ILE 132.A N ALA 121.A O no hydrogen 2.952 N/A ALA 133.A N ILE 36.A O no hydrogen 2.870 N/A ASN 134.A N THR 119.A O no hydrogen 2.752 N/A ALA 137.A N PRO 116.A O no hydrogen 3.029 N/A ALA 138.A N LEU 135.A O no hydrogen 2.847 N/A ASN 139.A N ALA 136.A O no hydrogen 2.923 N/A CYS 140.A N ALA 137.A O no hydrogen 2.819 N/A CYS 140.A SG ALA 136.A O no hydrogen 3.855 N/A TYR 141.A OH HIS 146.A ND1 no hydrogen 2.842 N/A LYS 142.A NZ CYS 140.A O no hydrogen 2.857 N/A LYS 143.A NZ ASP 148.A OD1 no hydrogen 3.534 N/A LYS 143.A NZ ASP 148.A OD2 no hydrogen 2.865 N/A LYS 145.A N LYS 142.A O no hydrogen 3.224 N/A HIS 146.A N LYS 143.A O no hydrogen 3.318 N/A HIS 146.A ND1 TYR 141.A OH no hydrogen 2.842 N/A ASP 148.A N LYS 143.A O no hydrogen 2.723 N/A ASN 152.A N LEU 149.A O no hydrogen 2.994 N/A TRP 153.A N LEU 149.A O no hydrogen 2.942 N/A TRP 153.A NE1 GLU 157.A OE2 no hydrogen 3.222 N/A MET 154.A N GLU 150.A O no hydrogen 3.092 N/A VAL 156.A N ASN 152.A O no hydrogen 3.390 N/A GLU 157.A N TRP 153.A O no hydrogen 3.087 N/A LYS 158.A N MET 154.A O no hydrogen 3.212 N/A LYS 158.A NZ GLU 3.A O no hydrogen 3.343 N/A LYS 158.A NZ ASN 4.A OD1 no hydrogen 2.816 N/A ALA 159.A N VAL 156.A O no hydrogen 3.085 N/A ARG 160.A N ILE 5.A O no hydrogen 2.886 N/A ARG 160.A NH1 GLU 157.A O no hydrogen 3.322 N/A ARG 160.A NH1 LYS 158.A O no hydrogen 3.442 N/A ARG 160.A NH1 ALA 159.A O no hydrogen 3.191 N/A VAL 161.A N ILE 5.A O no hydrogen 3.271 N/A CYS 162.A N ILE 189.A O no hydrogen 2.815 N/A TYR 163.A N PHE 7.A O no hydrogen 2.780 N/A ILE 164.A N THR 191.A O no hydrogen 3.042 N/A ALA 165.A N THR 63.A OG1 no hydrogen 3.038 N/A GLY 166.A N ASN 193.A O no hydrogen 2.739 N/A PHE 167.A N SER 195.A OG no hydrogen 3.163 N/A PHE 168.A N ALA 165.A O no hydrogen 3.155 N/A LEU 169.A N GLY 166.A O no hydrogen 2.851 N/A THR 170.A N PHE 167.A O no hydrogen 3.111 N/A THR 170.A OG1 PHE 167.A O no hydrogen 3.247 N/A VAL 171.A N PHE 168.A O no hydrogen 3.120 N/A SER 172.A N PHE 168.A O no hydrogen 3.048 N/A SER 172.A OG GLU 174.A OE2 no hydrogen 3.427 N/A SER 172.A OG SER 175.A OG no hydrogen 2.692 N/A SER 175.A N SER 172.A O no hydrogen 2.873 N/A SER 175.A N SER 172.A OG no hydrogen 3.262 N/A SER 175.A OG SER 172.A OG no hydrogen 2.692 N/A VAL 176.A N SER 172.A O no hydrogen 3.181 N/A LEU 177.A N PRO 173.A O no hydrogen 2.976 N/A LYS 178.A N GLU 174.A O no hydrogen 3.059 N/A LYS 178.A NZ ASP 148.A OD1 no hydrogen 2.452 N/A VAL 179.A N SER 175.A O no hydrogen 3.036 N/A ALA 180.A N VAL 176.A O no hydrogen 2.760 N/A HIS 181.A N LEU 177.A O no hydrogen 2.842 N/A HIS 181.A ND1 TYR 213.A OH no hydrogen 2.766 N/A HIS 182.A N LYS 178.A O no hydrogen 3.028 N/A ALA 183.A N VAL 179.A O no hydrogen 2.857 N/A SER 184.A N ALA 180.A O no hydrogen 3.113 N/A GLU 185.A N HIS 181.A O no hydrogen 2.945 N/A ASN 186.A N HIS 182.A O no hydrogen 3.230 N/A ASN 186.A N ALA 183.A O no hydrogen 3.300 N/A ASN 186.A ND2 HIS 182.A O no hydrogen 3.285 N/A ASN 187.A N SER 184.A O no hydrogen 3.163 N/A ARG 188.A N ALA 183.A O no hydrogen 2.737 N/A ILE 189.A N ARG 160.A O no hydrogen 3.230 N/A PHE 190.A N ASP 215.A OD2 no hydrogen 2.660 N/A THR 191.A N CYS 162.A O no hydrogen 2.762 N/A THR 191.A OG1 CYS 162.A O no hydrogen 2.551 N/A LEU 192.A N ILE 216.A O no hydrogen 3.053 N/A ASN 193.A ND2 TYR 163.A OH no hydrogen 2.707 N/A LEU 194.A N PHE 218.A O no hydrogen 3.041 N/A SER 195.A N ASN 193.A OD1 no hydrogen 3.064 N/A ALA 196.A N LEU 194.A O no hydrogen 2.725 N/A ILE 199.A N ALA 196.A O no hydrogen 2.958 N/A GLN 201.A N PRO 197.A O no hydrogen 3.115 N/A PHE 202.A N PHE 198.A O no hydrogen 3.021 N/A TYR 203.A N ILE 199.A O no hydrogen 2.881 N/A LEU 207.A N TYR 203.A O no hydrogen 2.838 N/A MET 208.A N LYS 204.A O no hydrogen 2.853 N/A LYS 209.A N GLU 205.A O no hydrogen 2.997 N/A VAL 210.A N SER 206.A O no hydrogen 3.169 N/A VAL 210.A N LEU 207.A O no hydrogen 3.138 N/A MET 211.A N LEU 207.A O no hydrogen 2.911 N/A TYR 213.A N VAL 210.A O no hydrogen 2.689 N/A TYR 213.A OH HIS 181.A ND1 no hydrogen 2.766 N/A VAL 214.A N MET 211.A O no hydrogen 2.952 N/A ASP 215.A N PHE 190.A O no hydrogen 2.693 N/A ILE 216.A N PHE 190.A O no hydrogen 3.387 N/A LEU 217.A N ILE 258.A O no hydrogen 3.018 N/A PHE 218.A N LEU 192.A O no hydrogen 2.868 N/A GLY 219.A N ILE 260.A O no hydrogen 3.012 N/A ASN 220.A N GLU 223.A OE1 no hydrogen 3.021 N/A GLU 221.A N GLU 221.A OE1 no hydrogen 2.977 N/A GLU 223.A N ASN 220.A OD1 no hydrogen 2.977 N/A ALA 224.A N ASN 220.A O no hydrogen 3.036 N/A ALA 225.A N GLU 221.A O no hydrogen 2.971 N/A THR 226.A N THR 222.A O no hydrogen 2.662 N/A THR 226.A OG1 THR 222.A O no hydrogen 2.839 N/A PHE 227.A N GLU 223.A O no hydrogen 2.751 N/A ALA 228.A N ALA 224.A O no hydrogen 2.833 N/A ARG 229.A N ALA 225.A O no hydrogen 2.929 N/A GLU 230.A N THR 226.A O no hydrogen 2.842 N/A GLN 231.A N PHE 227.A O no hydrogen 2.814 N/A GLY 232.A N ARG 229.A O no hydrogen 2.857 N/A PHE 233.A N ALA 228.A O no hydrogen 2.894 N/A THR 235.A N PHE 233.A O no hydrogen 2.832 N/A ASP 237.A N THR 235.A OG1 no hydrogen 3.076 N/A GLU 240.A N ASP 237.A OD2 no hydrogen 3.171 N/A ILE 241.A N ASP 237.A O no hydrogen 2.942 N/A ALA 242.A N ILE 238.A O no hydrogen 2.950 N/A LYS 243.A N LYS 239.A O no hydrogen 3.288 N/A LYS 244.A N GLU 240.A O no hydrogen 3.045 N/A THR 245.A N ILE 241.A O no hydrogen 2.930 N/A THR 245.A OG1 ILE 241.A O no hydrogen 2.562 N/A GLN 246.A N ALA 242.A O no hydrogen 2.792 N/A GLN 246.A NE2 ARG 257.A O no hydrogen 2.563 N/A ALA 247.A N LYS 243.A O no hydrogen 3.236 N/A ALA 247.A N LYS 244.A O no hydrogen 3.324 N/A LEU 248.A N THR 245.A O no hydrogen 3.337 N/A LYS 250.A NZ ASP 215.A OD1 no hydrogen 2.566 N/A LYS 250.A NZ ASN 252.A O no hydrogen 2.989 N/A LYS 250.A NZ ARG 255.A O no hydrogen 2.813 N/A MET 251.A N PRO 212.A O no hydrogen 3.006 N/A ASN 252.A ND2 ASN 187.A OD1 no hydrogen 2.926 N/A LYS 254.A N ASN 252.A OD1 no hydrogen 3.092 N/A ARG 255.A NE ASN 187.A OD1 no hydrogen 2.722 N/A ARG 255.A NH2 ASN 187.A O no hydrogen 2.753 N/A ARG 257.A NE VAL 214.A O no hydrogen 2.899 N/A ARG 257.A NH1 GLN 246.A O no hydrogen 3.106 N/A ARG 257.A NH1 LEU 248.A O no hydrogen 2.733 N/A ARG 257.A NH2 MET 211.A O no hydrogen 2.922 N/A ARG 257.A NH2 LEU 248.A O no hydrogen 3.439 N/A ARG 257.A NH2 PRO 249.A O no hydrogen 2.681 N/A ILE 258.A N ASP 215.A O no hydrogen 2.817 N/A VAL 259.A N ALA 271.A O no hydrogen 2.974 N/A ILE 260.A N LEU 217.A O no hydrogen 2.905 N/A PHE 261.A N ILE 269.A O no hydrogen 2.927 N/A THR 262.A N GLY 219.A O no hydrogen 2.793 N/A GLN 263.A NE2 ASP 267.A O no hydrogen 2.683 N/A ARG 265.A NE GLN 284.A OE1 no hydrogen 3.453 N/A ASP 266.A N GLN 263.A O no hydrogen 3.345 N/A THR 268.A N PHE 279.A O no hydrogen 2.764 N/A THR 268.A OG1 HIS 319.A NE2 no hydrogen 2.457 N/A ILE 269.A N PHE 261.A O no hydrogen 2.829 N/A MET 270.A N THR 277.A O no hydrogen 2.998 N/A ALA 271.A N VAL 259.A O no hydrogen 2.925 N/A THR 272.A N GLU 275.A O no hydrogen 2.854 N/A THR 272.A OG1 GLU 275.A O no hydrogen 3.389 N/A THR 277.A N MET 270.A O no hydrogen 2.841 N/A PHE 279.A N THR 268.A O no hydrogen 2.929 N/A GLN 284.A NE2 ARG 265.A O no hydrogen 3.445 N/A GLN 284.A NE2 VAL 281.A O no hydrogen 2.974 N/A GLY 292.A N ASP 289.A OD1 no hydrogen 3.175 N/A ALA 293.A N ASP 289.A O no hydrogen 3.004 N/A GLY 294.A N THR 290.A O no hydrogen 2.759 N/A ASP 295.A N ASN 291.A O no hydrogen 3.229 N/A ALA 296.A N GLY 292.A O no hydrogen 3.061 N/A PHE 297.A N ALA 293.A O no hydrogen 2.822 N/A VAL 298.A N GLY 294.A O no hydrogen 3.238 N/A GLY 299.A N ASP 295.A O no hydrogen 3.037 N/A GLY 300.A N ALA 296.A O no hydrogen 2.845 N/A PHE 301.A N PHE 297.A O no hydrogen 2.907 N/A LEU 302.A N VAL 298.A O no hydrogen 2.797 N/A SER 303.A N GLY 299.A O no hydrogen 3.027 N/A SER 303.A OG GLY 300.A O no hydrogen 2.602 N/A GLN 304.A N PHE 301.A O no hydrogen 3.311 N/A GLN 304.A NE2 SER 303.A OG no hydrogen 2.475 N/A LEU 305.A N PHE 301.A O no hydrogen 3.136 N/A VAL 306.A N LEU 302.A O no hydrogen 3.146 N/A SER 307.A N GLN 304.A O no hydrogen 2.979 N/A ASP 308.A N LEU 305.A O no hydrogen 3.040 N/A LYS 309.A N GLN 304.A O no hydrogen 3.237 N/A CYS 314.A N PRO 310.A O no hydrogen 3.005 N/A CYS 314.A SG PHE 301.A O no hydrogen 3.983 N/A CYS 314.A SG LYS 309.A O no hydrogen 3.737 N/A CYS 314.A SG PRO 310.A O no hydrogen 3.343 N/A ILE 315.A N LEU 311.A O no hydrogen 2.979 N/A ARG 316.A N THR 312.A O no hydrogen 3.036 N/A ARG 316.A NE GLU 313.A OE1 no hydrogen 3.037 N/A ARG 316.A NH2 GLU 313.A OE2 no hydrogen 2.661 N/A ALA 317.A N GLU 313.A O no hydrogen 2.975 N/A GLY 318.A N CYS 314.A O no hydrogen 2.894 N/A HIS 319.A N ILE 315.A O no hydrogen 2.842 N/A HIS 319.A NE2 THR 268.A OG1 no hydrogen 2.457 N/A TYR 320.A N ARG 316.A O no hydrogen 2.816 N/A ALA 321.A N ALA 317.A O no hydrogen 2.971 N/A ALA 322.A N GLY 318.A O no hydrogen 2.967 N/A SER 323.A N HIS 319.A O no hydrogen 3.312 N/A SER 323.A OG HIS 319.A O no hydrogen 3.557 N/A SER 323.A OG TYR 320.A O no hydrogen 2.703 N/A ILE 324.A N TYR 320.A O no hydrogen 3.242 N/A ILE 325.A N ALA 321.A O no hydrogen 3.188 N/A ILE 326.A N ALA 322.A O no hydrogen 3.049 N/A