Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4o3x_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 5.A N TYR 80.A O no hydrogen 3.064 N/A VAL 6.A N GLU 25.A O no hydrogen 2.951 N/A VAL 7.A N VAL 78.A O no hydrogen 2.753 N/A LYS 8.A NZ VAL 9.A O no hydrogen 2.784 N/A VAL 9.A N GLY 76.A O no hydrogen 2.768 N/A SER 12.A N ARG 131.A O no hydrogen 2.775 N/A SER 12.A OG LYS 130.A O no hydrogen 2.752 N/A SER 12.A OG ARG 131.A O no hydrogen 2.946 N/A SER 13.A N ASN 16.A O no hydrogen 2.844 N/A LYS 18.A NZ ASP 20.A OD1 no hydrogen 3.386 N/A LYS 18.A NZ ASP 20.A OD2 no hydrogen 2.951 N/A VAL 19.A N ALA 107.A O no hydrogen 2.943 N/A ILE 21.A N LYS 230.A O no hydrogen 2.878 N/A GLU 25.A N VAL 6.A O no hydrogen 3.036 N/A ILE 27.A N GLY 4.A O no hydrogen 2.810 N/A ASN 29.A ND2 ASP 34.A OD2 no hydrogen 2.601 N/A ASN 31.A N ASN 29.A OD1 no hydrogen 2.973 N/A ASN 31.A ND2 ASP 34.A OD2 no hydrogen 3.282 N/A ASP 33.A N ASN 31.A OD1 no hydrogen 3.355 N/A ASP 34.A N ASN 31.A O no hydrogen 3.092 N/A TYR 37.A OH GLU 25.A OE1 no hydrogen 2.632 N/A TYR 37.A OH GLU 25.A OE2 no hydrogen 2.969 N/A LYS 38.A N VAL 35.A O no hydrogen 2.993 N/A ASN 40.A N TYR 37.A O no hydrogen 3.089 N/A SER 41.A N LYS 38.A O no hydrogen 3.046 N/A SER 41.A OG LYS 38.A O no hydrogen 2.464 N/A LYS 43.A NZ ASN 40.A O no hydrogen 3.009 N/A LYS 43.A NZ GLU 74.A OE2 no hydrogen 3.251 N/A TYR 44.A N SER 41.A O no hydrogen 2.990 N/A TYR 44.A OH GLU 74.A OE2 no hydrogen 3.142 N/A ASN 45.A N ASP 66.A OD2 no hydrogen 3.120 N/A ASN 45.A ND2 GLU 68.A O no hydrogen 2.997 N/A TYR 46.A N ASP 66.A OD1 no hydrogen 3.066 N/A ASP 48.A N ILE 65.A O no hydrogen 2.682 N/A LYS 50.A N TYR 63.A O no hydrogen 3.200 N/A LYS 50.A NZ ASP 102.A OD1 no hydrogen 3.401 N/A LYS 50.A NZ ASP 102.A OD2 no hydrogen 2.634 N/A SER 55.A N ASP 53.A OD1 no hydrogen 3.185 N/A SER 55.A OG ASP 53.A OD1 no hydrogen 2.521 N/A LEU 56.A N ASP 53.A O no hydrogen 3.055 N/A GLN 57.A N GLU 220.A OE2 no hydrogen 2.504 N/A TYR 58.A N GLU 220.A OE1 no hydrogen 2.676 N/A VAL 59.A N GLU 220.A OE1 no hydrogen 2.930 N/A ARG 60.A N LYS 81.A O no hydrogen 2.806 N/A ARG 60.A NH1 LEU 32.A O no hydrogen 2.908 N/A ARG 60.A NH2 LYS 50.A O no hydrogen 2.994 N/A SER 61.A OG SER 237.A OG no hydrogen 2.871 N/A GLY 62.A N TYR 79.A O no hydrogen 3.154 N/A VAL 64.A N TYR 77.A O no hydrogen 2.776 N/A ILE 65.A N ASP 48.A O no hydrogen 2.824 N/A ASP 66.A N LYS 75.A O no hydrogen 2.674 N/A GLY 67.A N TYR 46.A O no hydrogen 2.701 N/A GLU 68.A N ASP 66.A OD1 no hydrogen 3.052 N/A HIS 69.A NE2 ASN 73.A O no hydrogen 2.497 N/A ASN 73.A N SER 70.A O no hydrogen 3.250 N/A LYS 75.A NZ ASP 66.A O no hydrogen 2.710 N/A LYS 75.A NZ ASP 138.A OD1 no hydrogen 2.683 N/A TYR 77.A N VAL 64.A O no hydrogen 2.823 N/A VAL 78.A N VAL 7.A O no hydrogen 2.834 N/A TYR 79.A N GLY 62.A O no hydrogen 3.178 N/A TYR 80.A N TYR 5.A O no hydrogen 3.069 N/A LYS 81.A N ARG 60.A O no hydrogen 2.791 N/A LYS 81.A NZ ASN 29.A O no hydrogen 2.542 N/A LYS 81.A NZ ASN 31.A O no hydrogen 2.937 N/A LYS 81.A NZ ASP 34.A O no hydrogen 2.951 N/A GLY 82.A N LEU 3.A O no hydrogen 2.878 N/A ASN 83.A N TYR 58.A O no hydrogen 2.876 N/A ASN 83.A ND2 GLY 30.A O no hydrogen 2.882 N/A ALA 86.A N PHE 213.A O no hydrogen 3.110 N/A LYS 87.A N PRO 216.A O no hydrogen 3.299 N/A GLU 88.A N PRO 216.A O no hydrogen 3.006 N/A LEU 95.A N VAL 152.A O no hydrogen 3.266 N/A TYR 97.A N PHE 150.A O no hydrogen 2.760 N/A TYR 97.A OH ALA 218.A O no hydrogen 2.914 N/A THR 98.A N LYS 239.A O no hydrogen 2.783 N/A GLY 99.A N SER 148.A O no hydrogen 3.105 N/A SER 100.A N SER 237.A O no hydrogen 3.121 N/A TRP 101.A N TYR 146.A O no hydrogen 3.258 N/A TRP 101.A NE1 SER 164.A O no hydrogen 2.822 N/A ASP 102.A N VAL 235.A O no hydrogen 2.788 N/A PHE 103.A N SER 136.A OG no hydrogen 3.116 N/A THR 104.A N PHE 233.A O no hydrogen 2.942 N/A THR 104.A OG1 SER 105.A O no hydrogen 3.101 N/A SER 105.A N LEU 134.A O no hydrogen 2.772 N/A SER 105.A OG ASN 106.A O no hydrogen 2.709 N/A ASN 106.A N SER 231.A O no hydrogen 2.831 N/A ASN 106.A ND2 ASP 20.A OD1 no hydrogen 2.885 N/A ALA 107.A N VAL 19.A O no hydrogen 2.936 N/A ASN 108.A N GLY 129.A O no hydrogen 3.000 N/A LEU 109.A N LYS 17.A O no hydrogen 2.644 N/A ASN 110.A N ASN 108.A OD1 no hydrogen 3.199 N/A ASN 110.A ND2 ASN 108.A OD1 no hydrogen 2.998 N/A GLU 113.A N ASN 110.A O no hydrogen 3.035 N/A GLY 114.A N ASN 111.A O no hydrogen 3.141 N/A ARG 115.A NE TYR 199.A OH no hydrogen 3.216 N/A ARG 115.A NH1 ASN 106.A O no hydrogen 3.007 N/A ARG 115.A NH1 ASN 106.A OD1 no hydrogen 3.217 N/A ARG 115.A NH1 GLY 129.A O no hydrogen 2.565 N/A ARG 115.A NH2 ASN 106.A OD1 no hydrogen 2.357 N/A ARG 115.A NH2 TYR 199.A OH no hydrogen 3.539 N/A ASP 122.A N LEU 119.A O no hydrogen 2.957 N/A TYR 123.A N LEU 119.A O no hydrogen 3.070 N/A TYR 124.A N ASP 138.A O no hydrogen 2.829 N/A THR 125.A OG1 LYS 126.A O no hydrogen 3.239 N/A ALA 127.A N ASN 117.A O no hydrogen 2.783 N/A LYS 130.A N ALA 127.A O no hydrogen 3.227 N/A GLY 133.A N PRO 10.A O no hydrogen 3.069 N/A LEU 134.A N SER 105.A OG no hydrogen 2.793 N/A VAL 135.A N ASP 138.A OD2 no hydrogen 2.932 N/A SER 136.A N PHE 103.A O no hydrogen 3.046 N/A SER 136.A OG ASP 102.A OD1 no hydrogen 2.770 N/A ASP 138.A N VAL 135.A O no hydrogen 2.878 N/A ALA 139.A N SER 136.A O no hydrogen 3.183 N/A LYS 140.A N ASP 122.A O no hydrogen 2.737 N/A LYS 140.A NZ ASN 120.A O no hydrogen 2.953 N/A LYS 143.A N LYS 140.A O no hydrogen 2.837 N/A HIS 144.A N LYS 140.A O no hydrogen 2.962 N/A HIS 144.A ND1 ASP 165.A OD2 no hydrogen 2.620 N/A HIS 144.A NE2 ASP 122.A OD1 no hydrogen 2.805 N/A LYS 145.A N ASP 165.A OD1 no hydrogen 3.135 N/A THR 147.A N SER 164.A O no hydrogen 3.057 N/A SER 148.A N GLY 99.A O no hydrogen 2.795 N/A SER 148.A OG SER 100.A O no hydrogen 3.025 N/A GLN 149.A N LYS 162.A O no hydrogen 2.918 N/A PHE 150.A N TYR 97.A O no hydrogen 2.858 N/A GLU 151.A N THR 160.A O no hydrogen 2.573 N/A VAL 152.A N LEU 95.A O no hydrogen 2.922 N/A ASP 153.A N LYS 158.A O no hydrogen 2.756 N/A ALA 155.A N ASP 153.A OD1 no hydrogen 2.989 N/A THR 156.A N ASP 153.A OD1 no hydrogen 3.288 N/A LYS 158.A N ASP 153.A O no hydrogen 2.993 N/A LYS 158.A NZ ASP 176.A OD1 no hydrogen 2.806 N/A MET 159.A N ALA 175.A O no hydrogen 2.987 N/A THR 160.A N GLU 151.A O no hydrogen 2.798 N/A GLY 161.A N VAL 173.A O no hydrogen 3.053 N/A LYS 162.A N GLN 149.A O no hydrogen 2.810 N/A LEU 163.A N TYR 171.A O no hydrogen 2.640 N/A SER 164.A N THR 147.A O no hydrogen 2.850 N/A ASP 165.A N LYS 168.A O no hydrogen 2.715 N/A LYS 166.A N LYS 145.A O no hydrogen 2.628 N/A LYS 166.A NZ PRO 141.A O no hydrogen 3.465 N/A LYS 166.A NZ ALA 142.A O no hydrogen 2.558 N/A LYS 168.A N ASP 165.A O no hydrogen 2.804 N/A ILE 170.A N LEU 163.A O no hydrogen 2.791 N/A TYR 171.A N LEU 163.A O no hydrogen 3.030 N/A THR 172.A N THR 187.A O no hydrogen 2.943 N/A VAL 173.A N GLY 161.A O no hydrogen 2.888 N/A ASN 174.A N ALA 185.A O no hydrogen 2.956 N/A ALA 175.A N MET 159.A O no hydrogen 3.059 N/A ASP 176.A N THR 183.A O no hydrogen 2.658 N/A ILE 177.A N LYS 157.A O no hydrogen 3.061 N/A ARG 178.A N ARG 181.A O no hydrogen 2.855 N/A ASN 180.A ND2 ALA 86.A O no hydrogen 2.891 N/A ARG 181.A N ARG 178.A O no hydrogen 3.267 N/A PHE 182.A N GLY 211.A O no hydrogen 2.914 N/A THR 183.A N ASP 176.A O no hydrogen 2.974 N/A GLY 184.A N LEU 209.A O no hydrogen 2.601 N/A ALA 185.A N ASN 174.A O no hydrogen 2.675 N/A ALA 186.A N SER 206.A O no hydrogen 2.869 N/A THR 187.A N THR 172.A O no hydrogen 2.701 N/A ALA 188.A N ASP 205.A OD1 no hydrogen 2.951 N/A SER 189.A N ILE 170.A O no hydrogen 2.922 N/A SER 189.A OG THR 169.A O no hydrogen 3.198 N/A LYS 191.A NZ ALA 188.A O no hydrogen 3.244 N/A LYS 191.A NZ ASP 205.A OD1 no hydrogen 3.051 N/A LYS 191.A NZ ASP 205.A OD2 no hydrogen 3.338 N/A ASN 192.A N ASP 190.A OD1 no hydrogen 3.002 N/A LYS 193.A NZ GLU 113.A OE2 no hydrogen 3.009 N/A GLY 196.A N GLY 114.A O no hydrogen 2.860 N/A SER 198.A OG LYS 195.A O no hydrogen 3.048 N/A TYR 199.A N GLY 196.A O no hydrogen 3.229 N/A TYR 199.A OH GLU 113.A OE2 no hydrogen 2.549 N/A ASN 200.A N LYS 193.A O no hydrogen 2.475 N/A ASN 200.A ND2 ASP 190.A O no hydrogen 3.023 N/A ASN 200.A ND2 ASN 192.A O no hydrogen 3.100 N/A PHE 202.A N ASN 200.A OD1 no hydrogen 2.972 N/A SER 206.A N ALA 186.A O no hydrogen 3.089 N/A SER 206.A OG SER 208.A OG no hydrogen 3.342 N/A SER 206.A OG VAL 226.A O no hydrogen 2.864 N/A GLN 207.A N ASN 228.A OD1 no hydrogen 2.953 N/A SER 208.A N SER 206.A OG no hydrogen 3.262 N/A SER 208.A OG SER 206.A OG no hydrogen 3.342 N/A SER 208.A OG VAL 226.A O no hydrogen 3.097 N/A LEU 209.A N GLY 184.A O no hydrogen 3.041 N/A GLU 210.A N LYS 224.A O no hydrogen 3.035 N/A GLY 211.A N PHE 182.A O no hydrogen 3.208 N/A GLY 212.A N ALA 222.A O no hydrogen 2.890 N/A PHE 213.A N ASN 180.A O no hydrogen 2.798 N/A TYR 214.A N GLU 220.A O no hydrogen 2.634 N/A GLY 215.A N SER 84.A O no hydrogen 2.531 N/A LYS 217.A N GLU 219.A OE1 no hydrogen 2.954 N/A LYS 217.A N GLU 219.A OE2 no hydrogen 3.317 N/A LYS 217.A NZ GLU 88.A OE2 no hydrogen 2.695 N/A ALA 218.A N GLY 215.A O no hydrogen 2.812 N/A GLU 219.A N GLU 219.A OE1 no hydrogen 2.745 N/A GLU 220.A N TYR 214.A O no hydrogen 3.045 N/A MET 221.A N ALA 238.A O no hydrogen 2.932 N/A ALA 222.A N GLY 212.A O no hydrogen 3.065 N/A GLY 223.A N PHE 236.A O no hydrogen 3.033 N/A LYS 224.A N GLU 210.A O no hydrogen 2.981 N/A PHE 225.A N ALA 234.A O no hydrogen 2.966 N/A VAL 226.A N SER 208.A OG no hydrogen 3.287 N/A ALA 227.A N LEU 232.A O no hydrogen 2.858 N/A ASN 228.A N ASP 205.A O no hydrogen 2.963 N/A ASN 228.A ND2 GLN 207.A OE1 no hydrogen 3.022 N/A LYS 230.A N ALA 227.A O no hydrogen 2.914 N/A SER 231.A N ASP 229.A OD1 no hydrogen 3.392 N/A SER 231.A OG ASP 229.A OD1 no hydrogen 2.701 N/A SER 231.A OG ASP 229.A OD2 no hydrogen 3.367 N/A PHE 233.A N THR 104.A O no hydrogen 2.948 N/A ALA 234.A N PHE 225.A O no hydrogen 2.908 N/A VAL 235.A N ASP 102.A O no hydrogen 2.743 N/A PHE 236.A N GLY 223.A O no hydrogen 3.093 N/A SER 237.A N SER 100.A O no hydrogen 3.282 N/A SER 237.A OG SER 61.A OG no hydrogen 2.871 N/A ALA 238.A N MET 221.A O no hydrogen 2.926 N/A LYS 239.A N THR 98.A O no hydrogen 3.113 N/A LYS 239.A NZ SER 55.A O no hydrogen 3.495 N/A LYS 239.A NZ GLU 220.A OE2 no hydrogen 3.185 N/A HIS 240.A N GLU 219.A O no hydrogen 3.296 N/A ASN 241.A N THR 96.A O no hydrogen 3.187 N/A