Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4opq_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 4.A OG1 SER 253.A OG no hydrogen 3.144 N/A LYS 7.A N GLU 3.A O no hydrogen 3.191 N/A LYS 7.A NZ ASP 10.A OD2.A no hydrogen 3.169 N/A LYS 7.A NZ GLN 246.A OE1 no hydrogen 2.825 N/A LYS 7.A NZ GLU 249.A OE1 no hydrogen 2.720 N/A VAL 8.A N THR 4.A O no hydrogen 2.812 N/A LYS 9.A N LEU 5.A O no hydrogen 2.942 N/A ASP 10.A N VAL 6.A O no hydrogen 2.892 N/A ALA 11.A N LYS 7.A O no hydrogen 2.878 N/A GLU 12.A N VAL 8.A O no hydrogen 3.085 N/A ASP 13.A N LYS 9.A O no hydrogen 3.108 N/A GLN 14.A N ASP 10.A O no hydrogen 2.864 N/A GLN 14.A NE2.B ASP 10.A OD1.A no hydrogen 3.108 N/A LEU 15.A N ALA 11.A O no hydrogen 2.958 N/A LEU 15.A N GLU 12.A O no hydrogen 3.256 N/A GLY 16.A N GLU 12.A O no hydrogen 2.947 N/A ARG 18.A N THR 234.A O no hydrogen 2.932 N/A ARG 18.A NH1 GLU 39.A OE1 no hydrogen 3.014 N/A ARG 18.A NH1 ARG 40.A O no hydrogen 3.157 N/A ARG 18.A NH2 ARG 40.A O no hydrogen 2.913 N/A VAL 19.A N GLU 12.A OE1 no hydrogen 2.947 N/A GLY 20.A N TYR 232.A O no hydrogen 2.743 N/A TYR 21.A N PHE 35.A O no hydrogen 2.941 N/A ILE 22.A N VAL 230.A O no hydrogen 3.031 N/A GLU 23.A N GLU 33.A O no hydrogen 2.974 N/A LEU 24.A N ILE 228.A O no hydrogen 2.772 N/A ASP 25.A N LYS 30.A O no hydrogen 2.866 N/A LEU 26.A N SER 226.A O no hydrogen 2.970 N/A SER 28.A N ASP 25.A OD2 no hydrogen 2.929 N/A SER 28.A OG ASP 25.A OD2 no hydrogen 2.686 N/A GLY 29.A N ASP 25.A O no hydrogen 2.865 N/A LYS 30.A N SER 28.A OG no hydrogen 3.124 N/A LEU 32.A N GLU 23.A O no hydrogen 2.907 N/A PHE 35.A N TYR 21.A O no hydrogen 2.973 N/A ARG 36.A NE GLU 12.A OE1 no hydrogen 2.880 N/A ARG 36.A NH1 GLU 39.A OE1 no hydrogen 3.022 N/A ARG 36.A NH1 GLU 39.A OE2 no hydrogen 3.138 N/A ARG 36.A NH2 GLU 12.A OE1 no hydrogen 3.489 N/A ARG 36.A NH2 GLU 12.A OE2 no hydrogen 2.892 N/A GLU 39.A N ARG 36.A O no hydrogen 3.341 N/A ARG 40.A NH1 VAL 134.A O no hydrogen 2.937 N/A ARG 40.A NH1 THR 150.A OG1 no hydrogen 2.848 N/A ARG 40.A NH2 VAL 134.A O no hydrogen 3.155 N/A PHE 41.A N THR 151.A O no hydrogen 2.912 N/A MET 43.A N ASP 149.A O no hydrogen 3.070 N/A SER 45.A OG SER 105.A OG no hydrogen 3.186 N/A THR 46.A N MET 43.A O no hydrogen 3.113 N/A THR 46.A OG1 MET 43.A O no hydrogen 2.690 N/A THR 46.A OG1 TYR 232.A OH no hydrogen 2.736 N/A PHE 47.A N MET 44.A O no hydrogen 3.389 N/A LYS 48.A N SER 45.A O no hydrogen 3.042 N/A LYS 48.A NZ SER 45.A OG no hydrogen 2.819 N/A LYS 48.A NZ SER 105.A O no hydrogen 2.837 N/A LYS 48.A NZ ASN 107.A OD1 no hydrogen 2.802 N/A LYS 48.A NZ GLU 141.A OE2 no hydrogen 3.345 N/A VAL 49.A N THR 46.A O no hydrogen 3.388 N/A LEU 51.A N PHE 47.A O no hydrogen 2.942 N/A CYS 52.A N LYS 48.A O no hydrogen 3.141 N/A CYS 52.A SG LYS 48.A O no hydrogen 3.821 N/A GLY 53.A N VAL 49.A O no hydrogen 2.982 N/A ALA 54.A N LEU 50.A O no hydrogen 2.998 N/A VAL 55.A N LEU 51.A O no hydrogen 3.028 N/A LEU 56.A N CYS 52.A O no hydrogen 2.864 N/A SER 57.A N GLY 53.A O no hydrogen 2.935 N/A ARG 58.A N.A ALA 54.A O no hydrogen 3.065 N/A ARG 58.A N.B ALA 54.A O no hydrogen 3.055 N/A VAL 59.A N VAL 55.A O no hydrogen 2.993 N/A ASP 60.A N LEU 56.A O no hydrogen 2.840 N/A ALA 61.A N SER 57.A O no hydrogen 3.068 N/A GLY 62.A N VAL 59.A O no hydrogen 3.012 N/A GLN 63.A N ARG 58.A O.A no hydrogen 2.978 N/A GLN 63.A N ARG 58.A O.B no hydrogen 2.762 N/A GLN 63.A NE2.A ALA 61.A O no hydrogen 3.403 N/A GLN 65.A N GLU 64.A OE1 no hydrogen 2.836 N/A ARG 68.A N GLN 65.A O no hydrogen 3.180 N/A ARG 68.A NE GLU 64.A OE1 no hydrogen 2.808 N/A ARG 68.A NH2 GLU 64.A OE2 no hydrogen 2.889 N/A ARG 69.A NH1 ASP 90.A O no hydrogen 2.930 N/A ILE 70.A N MET 92.A O no hydrogen 2.880 N/A TYR 72.A OH THR 84.A O no hydrogen 2.667 N/A SER 73.A N ASP 76.A OD2 no hydrogen 2.801 N/A SER 73.A OG.B ASP 76.A OD2 no hydrogen 2.937 N/A ASN 75.A N SER 73.A OG.A no hydrogen 2.959 N/A ASP 76.A N SER 73.A O no hydrogen 2.911 N/A LEU 77.A N GLN 74.A O no hydrogen 3.226 N/A VAL 78.A N THR 108.A OG1 no hydrogen 2.962 N/A TYR 80.A OH MET 104.A O no hydrogen 2.730 N/A SER 81.A OG VAL 78.A O no hydrogen 2.675 N/A SER 81.A OG THR 108.A OG1 no hydrogen 2.607 N/A VAL 83.A N ASP 106.A OD2 no hydrogen 2.801 N/A THR 84.A N ASP 106.A OD2 no hydrogen 2.873 N/A THR 84.A OG1 ASP 106.A OD1 no hydrogen 2.910 N/A THR 84.A OG1 ASP 106.A OD2 no hydrogen 3.297 N/A GLU 85.A N SER 81.A O no hydrogen 3.043 N/A LYS 86.A N VAL 83.A O no hydrogen 3.000 N/A LYS 86.A NZ PRO 82.A O no hydrogen 2.819 N/A HIS 87.A N THR 84.A O no hydrogen 3.190 N/A HIS 87.A ND1 ASP 90.A OD1 no hydrogen 3.079 N/A HIS 87.A ND1 ASP 90.A OD2 no hydrogen 2.793 N/A GLY 91.A N HIS 87.A O no hydrogen 2.884 N/A MET 92.A N ILE 70.A O no hydrogen 3.225 N/A THR 93.A N GLU 96.A OE1 no hydrogen 2.952 N/A THR 93.A OG1 LEU 66.A O no hydrogen 3.488 N/A VAL 94.A N ARG 68.A O no hydrogen 2.971 N/A GLY 95.A N LEU 66.A O no hydrogen 2.880 N/A GLU 96.A N THR 93.A OG1 no hydrogen 3.073 N/A LEU 97.A N THR 93.A O no hydrogen 2.861 N/A CYS 98.A N VAL 94.A O no hydrogen 2.982 N/A SER 99.A N GLY 95.A O no hydrogen 2.918 N/A ALA 100.A N GLU 96.A O no hydrogen 2.847 N/A ALA 101.A N LEU 97.A O no hydrogen 2.830 N/A ILE 102.A N CYS 98.A O no hydrogen 2.921 N/A THR 103.A N SER 99.A O no hydrogen 2.705 N/A THR 103.A OG1 SER 99.A O no hydrogen 2.802 N/A MET 104.A N ALA 100.A O no hydrogen 3.013 N/A ASP 106.A N ALA 100.A O no hydrogen 3.141 N/A ASN 107.A N TYR 80.A O no hydrogen 2.905 N/A ASN 107.A ND2 GLU 79.A O no hydrogen 2.927 N/A THR 108.A OG1 SER 81.A OG no hydrogen 2.607 N/A ALA 109.A N ASP 106.A OD1 no hydrogen 2.875 N/A ALA 110.A N ASP 106.A O no hydrogen 3.273 N/A ASN 111.A N ASN 107.A O no hydrogen 3.055 N/A ASN 111.A ND2 GLU 141.A O no hydrogen 3.011 N/A LEU 112.A N THR 108.A O no hydrogen 2.848 N/A LEU 113.A N ALA 109.A O no hydrogen 3.062 N/A LEU 114.A N ALA 110.A O no hydrogen 2.852 N/A THR 115.A N ASN 111.A O no hydrogen 3.046 N/A THR 115.A OG1.A ASN 111.A O no hydrogen 3.288 N/A THR 115.A OG1.B LEU 112.A O no hydrogen 2.739 N/A THR 116.A N LEU 112.A O no hydrogen 3.239 N/A THR 116.A N LEU 113.A O no hydrogen 3.049 N/A THR 116.A OG1 LEU 113.A O no hydrogen 2.717 N/A ILE 117.A N LEU 114.A O no hydrogen 3.220 N/A GLY 118.A N THR 115.A O no hydrogen 3.211 N/A GLY 119.A N LEU 114.A O no hydrogen 2.887 N/A GLU 122.A N GLY 119.A O no hydrogen 3.032 N/A LEU 123.A N GLY 119.A O no hydrogen 3.363 N/A THR 124.A N PRO 120.A O no hydrogen 3.123 N/A THR 124.A OG1 PRO 120.A O no hydrogen 3.403 N/A THR 124.A OG1 LEU 137.A O no hydrogen 2.931 N/A ALA 125.A N LYS 121.A O no hydrogen 2.967 N/A PHE 126.A N GLU 122.A O no hydrogen 3.095 N/A LEU 127.A N LEU 123.A O no hydrogen 2.953 N/A HIS 128.A N THR 124.A O no hydrogen 2.949 N/A ASN 129.A N ALA 125.A O no hydrogen 2.865 N/A MET 130.A N PHE 126.A O no hydrogen 3.142 N/A MET 130.A N LEU 127.A O no hydrogen 3.096 N/A GLY 131.A N HIS 128.A O no hydrogen 3.029 N/A ASP 132.A N LEU 127.A O no hydrogen 3.086 N/A VAL 134.A N ASP 132.A OD1 no hydrogen 2.922 N/A THR 135.A N ASP 132.A OD1 no hydrogen 2.915 N/A THR 135.A OG1 ASP 132.A OD1 no hydrogen 3.259 N/A THR 135.A OG1 ASP 132.A OD2 no hydrogen 2.661 N/A THR 135.A OG1 THR 151.A OG1 no hydrogen 2.822 N/A ARG 136.A N THR 150.A O no hydrogen 3.036 N/A ARG 136.A NE ASP 138.A OD1 no hydrogen 3.423 N/A ARG 136.A NE ASP 138.A OD2 no hydrogen 2.938 N/A ARG 136.A NH1 GLU 147.A OE2 no hydrogen 3.272 N/A ARG 136.A NH2 ASP 138.A OD1 no hydrogen 2.878 N/A LEU 137.A N THR 124.A OG1 no hydrogen 2.933 N/A ASP 138.A N ASP 149.A OD1 no hydrogen 2.754 N/A SER 139.A N ASP 149.A OD1 no hydrogen 3.088 N/A SER 139.A OG ASP 149.A OD1 no hydrogen 3.566 N/A SER 139.A OG ASP 149.A OD2 no hydrogen 2.593 N/A GLU 141.A N ASN 111.A OD1 no hydrogen 2.936 N/A GLU 143.A N TRP 140.A O no hydrogen 3.085 N/A ASN 145.A ND2 PRO 142.A O no hydrogen 3.181 N/A ARG 148.A N ASP 146.A OD2 no hydrogen 3.282 N/A ARG 148.A NH1 ASP 146.A OD2 no hydrogen 3.097 N/A ASP 149.A N ASP 138.A OD2 no hydrogen 2.952 N/A THR 150.A OG1 GLU 147.A O no hydrogen 2.641 N/A THR 151.A N PHE 41.A O no hydrogen 3.005 N/A THR 151.A OG1 THR 135.A OG1 no hydrogen 2.822 N/A THR 151.A OG1 THR 152.A O no hydrogen 3.342 N/A VAL 154.A N PRO 37.A O no hydrogen 3.051 N/A ALA 155.A N THR 152.A OG1 no hydrogen 3.060 N/A MET 156.A N THR 152.A O no hydrogen 2.955 N/A ALA 157.A N PRO 153.A O no hydrogen 2.928 N/A THR 158.A N.A VAL 154.A O no hydrogen 3.040 N/A THR 158.A N.B VAL 154.A O no hydrogen 3.079 N/A THR 158.A OG1.A VAL 154.A O no hydrogen 2.767 N/A THR 158.A OG1.B VAL 154.A O no hydrogen 2.918 N/A THR 158.A OG1.B ALA 155.A O no hydrogen 3.262 N/A THR 159.A N ALA 155.A O no hydrogen 2.850 N/A THR 159.A OG1 ASP 132.A OD2 no hydrogen 2.601 N/A THR 159.A OG1 ALA 155.A O no hydrogen 3.139 N/A LEU 160.A N MET 156.A O no hydrogen 2.849 N/A ARG 161.A N ALA 157.A O no hydrogen 2.814 N/A ARG 161.A NE LEU 26.A O no hydrogen 2.768 N/A ARG 161.A NH2 ALA 27.A O no hydrogen 2.845 N/A LYS 162.A N THR 158.A O.A no hydrogen 2.840 N/A LYS 162.A N THR 158.A O.B no hydrogen 3.028 N/A LYS 162.A NZ MET 130.A O no hydrogen 2.883 N/A LEU 163.A N THR 159.A O no hydrogen 2.984 N/A LEU 164.A N LEU 160.A O no hydrogen 2.961 N/A LEU 164.A N ARG 161.A O no hydrogen 3.153 N/A THR 165.A N ARG 161.A O no hydrogen 2.865 N/A THR 165.A OG1 ARG 161.A O no hydrogen 3.005 N/A GLY 166.A N LYS 162.A O no hydrogen 3.048 N/A THR 170.A N ASP 60.A OD2 no hydrogen 2.814 N/A THR 170.A OG1 ASP 60.A OD1 no hydrogen 2.684 N/A THR 170.A OG1 ASP 60.A OD2 no hydrogen 3.372 N/A SER 173.A N THR 170.A OG1 no hydrogen 3.358 N/A SER 173.A OG ASP 60.A OD1 no hydrogen 2.686 N/A SER 173.A OG ASP 60.A OD2 no hydrogen 3.511 N/A ARG 174.A N THR 170.A O no hydrogen 2.834 N/A ARG 174.A NH1 LEU 169.A O no hydrogen 2.879 N/A GLN 175.A N ALA 171.A O no hydrogen 3.035 N/A GLN 175.A NE2 ASP 179.A OD1 no hydrogen 2.863 N/A GLN 176.A N ALA 172.A O no hydrogen 2.951 N/A LEU 177.A N SER 173.A O no hydrogen 2.990 N/A ILE 178.A N ARG 174.A O no hydrogen 3.115 N/A ASP 179.A N GLN 175.A O no hydrogen 2.893 N/A TRP 180.A N GLN 176.A O no hydrogen 3.085 N/A MET 181.A N LEU 177.A O no hydrogen 3.150 N/A GLU 182.A N ILE 178.A O no hydrogen 2.831 N/A ALA 183.A N ASP 179.A O no hydrogen 3.250 N/A ALA 183.A N TRP 180.A O no hydrogen 3.292 N/A ASP 184.A N MET 181.A O no hydrogen 3.216 N/A LYS 185.A N THR 103.A O no hydrogen 2.948 N/A VAL 186.A N ASP 184.A OD1 no hydrogen 3.244 N/A LEU 190.A N ALA 187.A O no hydrogen 3.194 N/A ARG 192.A NE ASP 203.A OD1 no hydrogen 3.067 N/A ARG 192.A NE ASP 203.A OD2 no hydrogen 3.085 N/A ARG 192.A NH2 GLU 182.A O no hydrogen 3.146 N/A ARG 192.A NH2 ASP 203.A OD1 no hydrogen 2.914 N/A SER 193.A N LEU 190.A O no hydrogen 3.114 N/A SER 193.A OG LEU 190.A O no hydrogen 2.674 N/A ALA 194.A N LEU 191.A O no hydrogen 2.872 N/A LEU 195.A N ARG 192.A O no hydrogen 3.339 N/A PHE 200.A N GLY 220.A O no hydrogen 2.863 N/A ALA 202.A N ALA 218.A O no hydrogen 2.898 N/A ASP 203.A N MET 181.A O no hydrogen 3.142 N/A LYS 204.A N ILE 216.A O no hydrogen 3.022 N/A LYS 204.A NZ SER 105.A OG no hydrogen 2.837 N/A LYS 204.A NZ SER 205.A O no hydrogen 2.856 N/A GLY 206.A N GLY 214.A O no hydrogen 2.993 N/A SER 208.A N SER 212.A O no hydrogen 3.164 N/A SER 212.A OG THR 234.A OG1 no hydrogen 2.837 N/A ARG 213.A N MET 233.A O no hydrogen 3.043 N/A ARG 213.A NE ASN 244.A OD1 no hydrogen 2.891 N/A ARG 213.A NH1 GLY 206.A O no hydrogen 3.070 N/A ARG 213.A NH2 ASN 244.A OD1 no hydrogen 2.948 N/A GLY 214.A N GLY 206.A O no hydrogen 2.926 N/A ILE 215.A N ILE 231.A O no hydrogen 2.819 N/A ILE 216.A N LYS 204.A O no hydrogen 2.957 N/A ALA 217.A N VAL 229.A O no hydrogen 2.856 N/A ALA 218.A N ALA 202.A O no hydrogen 2.861 N/A LEU 219.A N ARG 227.A O no hydrogen 2.989 N/A GLY 220.A N PHE 200.A O no hydrogen 3.157 N/A GLY 223.A N GLY 198.A O no hydrogen 3.149 N/A SER 226.A N LEU 219.A O no hydrogen 2.866 N/A ARG 227.A N LEU 219.A O no hydrogen 3.080 N/A ARG 227.A NH1 GLU 23.A OE2 no hydrogen 2.630 N/A ARG 227.A NH1 TRP 258.A O no hydrogen 3.252 N/A ARG 227.A NH2 TRP 258.A O no hydrogen 2.910 N/A ILE 228.A N LEU 24.A O no hydrogen 2.918 N/A VAL 229.A N ALA 217.A O no hydrogen 2.871 N/A VAL 230.A N ILE 22.A O no hydrogen 2.990 N/A ILE 231.A N ILE 215.A O no hydrogen 2.886 N/A TYR 232.A N GLY 20.A O no hydrogen 2.998 N/A TYR 232.A OH THR 46.A OG1 no hydrogen 2.736 N/A MET 233.A N ARG 213.A O no hydrogen 2.829 N/A THR 234.A N ARG 18.A O no hydrogen 2.959 N/A THR 234.A OG1 SER 212.A OG no hydrogen 2.837 N/A THR 239.A N GLU 242.A OE2 no hydrogen 3.237 N/A GLU 242.A N THR 239.A OG1 no hydrogen 3.189 N/A ARG 243.A N THR 239.A O no hydrogen 3.020 N/A ARG 243.A NE ALA 238.A O no hydrogen 3.258 N/A ARG 243.A NE THR 239.A O no hydrogen 3.316 N/A ARG 243.A NH1 SER 208.A O no hydrogen 3.070 N/A ARG 243.A NH1 SER 212.A O no hydrogen 3.064 N/A ARG 243.A NH2 GLU 209.A O no hydrogen 3.330 N/A ARG 243.A NH2 ALA 238.A O no hydrogen 3.320 N/A ASN 244.A N MET 240.A O no hydrogen 2.892 N/A ARG 245.A N ASP 241.A O no hydrogen 3.023 N/A ARG 245.A NH1 GLU 249.A OE2 no hydrogen 2.448 N/A GLN 246.A N GLU 242.A O no hydrogen 3.129 N/A GLN 246.A NE2 GLN 14.A OE1.B no hydrogen 3.486 N/A ILE 247.A N ARG 243.A O no hydrogen 3.256 N/A ALA 248.A N ASN 244.A O no hydrogen 2.947 N/A GLU 249.A N ARG 245.A O no hydrogen 2.789 N/A ILE 250.A N GLN 246.A O no hydrogen 2.924 N/A GLY 251.A N ILE 247.A O no hydrogen 2.912 N/A ALA 252.A N ALA 248.A O no hydrogen 2.931 N/A SER 253.A N GLU 249.A O no hydrogen 3.096 N/A SER 253.A OG PRO 2.A O no hydrogen 2.500 N/A SER 253.A OG THR 4.A OG1 no hydrogen 3.144 N/A LEU 254.A N.A ILE 250.A O no hydrogen 3.027 N/A LEU 254.A N.B ILE 250.A O no hydrogen 2.975 N/A ILE 255.A N GLY 251.A O no hydrogen 3.069 N/A LYS 256.A N ALA 252.A O no hydrogen 2.854 N/A HIS 257.A N SER 253.A O no hydrogen 3.091 N/A HIS 257.A NE2 HIS 1.A O no hydrogen 3.151 N/A TRP 258.A N ILE 255.A O no hydrogen 3.167 N/A