Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4p6v_F.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 4.A N SER 1.A O no hydrogen 3.291 N/A PHE 5.A N SER 1.A O no hydrogen 3.391 N/A VAL 8.A N ILE 4.A O no hydrogen 2.783 N/A MET 9.A N PHE 5.A O no hydrogen 3.102 N/A THR 11.A N VAL 8.A O no hydrogen 3.311 N/A LEU 12.A N MET 9.A O no hydrogen 3.249 N/A ILE 13.A N MET 9.A O no hydrogen 3.370 N/A LEU 15.A N THR 11.A O no hydrogen 2.877 N/A ALA 16.A N LEU 12.A O no hydrogen 2.276 N/A LEU 17.A N ILE 13.A O no hydrogen 3.238 N/A VAL 18.A N ILE 14.A O no hydrogen 3.133 N/A LEU 19.A N LEU 15.A O no hydrogen 3.121 N/A VAL 20.A N ALA 16.A O no hydrogen 2.933 N/A ILE 21.A N LEU 17.A O no hydrogen 2.705 N/A LEU 22.A N VAL 18.A O no hydrogen 2.625 N/A PHE 23.A N LEU 19.A O no hydrogen 2.841 N/A ALA 24.A N VAL 20.A O no hydrogen 2.841 N/A LYS 25.A N ILE 21.A O no hydrogen 3.232 N/A SER 26.A N LEU 22.A O no hydrogen 2.493 N/A SER 26.A OG SER 26.A O no hydrogen 2.603 N/A LEU 28.A N LYS 25.A O no hydrogen 3.437 N/A VAL 29.A N LYS 25.A O no hydrogen 3.142 N/A SER 37.A N MET 118.A O no hydrogen 2.849 N/A SER 37.A OG GLU 43.A OE1 no hydrogen 2.762 N/A GLY 40.A N ASN 39.A OD1 no hydrogen 2.591 N/A ILE 46.A N ILE 36.A O no hydrogen 3.084 N/A LEU 54.A N VAL 112.A O no hydrogen 3.137 N/A THR 56.A OG1 LYS 53.A O no hydrogen 2.534 N/A ALA 57.A N LYS 53.A O no hydrogen 3.116 N/A LEU 58.A N LEU 54.A O no hydrogen 3.025 N/A ALA 59.A N LEU 55.A O no hydrogen 3.369 N/A GLY 60.A N THR 56.A O no hydrogen 3.180 N/A GLY 60.A N ALA 57.A O no hydrogen 3.231 N/A CYS 69.A SG GLY 71.A O no hydrogen 3.579 N/A SER 74.A OG GLY 72.A O no hydrogen 3.094 N/A LYS 83.A NZ GLU 121.A OE1 no hydrogen 3.546 N/A LEU 94.A N LEU 90.A O no hydrogen 2.694 N/A HIS 96.A ND1 THR 92.A O no hydrogen 3.313 N/A ILE 97.A N GLU 93.A O no hydrogen 3.077 N/A ALA 102.A N GLU 101.A OE1 no hydrogen 2.774 N/A ARG 103.A NH1 ARG 103.A O no hydrogen 3.251 N/A GLY 105.A N ALA 102.A O no hydrogen 2.614 N/A ARG 107.A NH1 GLU 93.A OE1 no hydrogen 2.896 N/A GLN 111.A N LEU 108.A O no hydrogen 3.238 N/A VAL 112.A N LEU 108.A O no hydrogen 2.951 N/A LEU 120.A N SER 37.A O no hydrogen 2.597 N/A GLU 121.A N LYS 81.A O no hydrogen 3.246 N/A TRP 132.A N ILE 259.A O no hydrogen 2.986 N/A CYS 134.A N CYS 257.A O no hydrogen 2.391 N/A THR 135.A N ALA 152.A O no hydrogen 3.114 N/A VAL 136.A N ASP 255.A O no hydrogen 3.227 N/A ILE 137.A N LYS 150.A O no hydrogen 2.496 N/A SER 138.A N LYS 150.A O no hydrogen 3.322 N/A ASN 139.A ND2 ILE 248.A O no hydrogen 3.383 N/A ASN 139.A ND2 LEU 251.A O no hydrogen 3.170 N/A ASN 141.A ND2 ALA 143.A O no hydrogen 3.050 N/A LYS 142.A N ILE 146.A O no hydrogen 2.793 N/A LYS 142.A NZ GLU 148.A OE1 no hydrogen 3.411 N/A ALA 143.A N ILE 146.A O no hydrogen 3.265 N/A THR 144.A N GLU 315.A OE1 no hydrogen 2.715 N/A THR 144.A OG1 GLU 315.A OE1 no hydrogen 3.036 N/A THR 144.A OG1 GLU 315.A OE2 no hydrogen 2.538 N/A ILE 146.A N ALA 143.A O no hydrogen 3.528 N/A LYS 147.A N VAL 227.A O no hydrogen 3.494 N/A LYS 147.A NZ ASN 139.A O no hydrogen 3.288 N/A LYS 147.A NZ ASN 141.A OD1 no hydrogen 2.697 N/A LYS 147.A NZ ASP 182.A O no hydrogen 2.938 N/A GLU 148.A N ASP 140.A O no hydrogen 2.599 N/A LEU 149.A N LEU 225.A O no hydrogen 3.246 N/A LYS 150.A N SER 138.A O no hydrogen 2.819 N/A LEU 151.A N ILE 223.A O no hydrogen 3.251 N/A ALA 152.A N THR 135.A O no hydrogen 2.622 N/A ILE 153.A N GLY 221.A O no hydrogen 3.429 N/A GLY 156.A N ILE 153.A O no hydrogen 3.286 N/A GLY 165.A N ARG 162.A O no hydrogen 3.009 N/A TYR 166.A N PHE 263.A O no hydrogen 3.054 N/A ILE 167.A N TYR 211.A O no hydrogen 2.772 N/A GLN 168.A N SER 260.A O no hydrogen 2.881 N/A ILE 169.A N ARG 209.A O no hydrogen 2.936 N/A GLU 170.A N THR 258.A O no hydrogen 3.074 N/A ALA 171.A N ILE 207.A O no hydrogen 3.166 N/A HIS 174.A N VAL 203.A O no hydrogen 3.349 N/A HIS 174.A ND1 PRO 172.A O no hydrogen 2.423 N/A HIS 175.A NE2 GLU 200.A OE1 no hydrogen 2.599 N/A VAL 176.A N SER 201.A O no hydrogen 2.926 N/A TYR 178.A N TYR 199.A O no hydrogen 2.909 N/A TYR 178.A OH SER 246.A OG no hydrogen 2.746 N/A ASP 180.A N LYS 177.A O no hydrogen 3.021 N/A PHE 181.A N TYR 178.A O no hydrogen 2.862 N/A LYS 186.A NZ TYR 187.A OH no hydrogen 3.061 N/A TYR 187.A N PRO 184.A O no hydrogen 2.833 N/A TYR 187.A OH ARG 314.A O no hydrogen 3.231 N/A ARG 188.A N GLU 185.A O no hydrogen 3.068 N/A ARG 188.A NH1 VAL 183.A O no hydrogen 3.563 N/A TRP 191.A NE1 THR 144.A O no hydrogen 3.025 N/A ASP 192.A N ARG 188.A O no hydrogen 2.759 N/A LYS 193.A N GLY 189.A O no hydrogen 2.743 N/A PHE 194.A N ASP 190.A O no hydrogen 3.000 N/A ASN 195.A N ASP 192.A O no hydrogen 3.285 N/A LEU 196.A N TRP 191.A O no hydrogen 2.781 N/A ARG 198.A N ASN 195.A O no hydrogen 3.146 N/A ARG 198.A NE ASN 195.A O no hydrogen 3.124 N/A ARG 198.A NH2 PHE 194.A O no hydrogen 3.053 N/A TYR 199.A N LEU 196.A O no hydrogen 3.425 N/A SER 201.A N VAL 176.A O no hydrogen 2.930 N/A LYS 202.A NZ ASP 204.A OD1 no hydrogen 3.087 N/A VAL 203.A N HIS 174.A O no hydrogen 3.264 N/A ARG 209.A N ILE 169.A O no hydrogen 3.249 N/A ARG 209.A NH1 ILE 208.A O no hydrogen 2.779 N/A TYR 211.A N ILE 167.A O no hydrogen 2.701 N/A MET 213.A N GLY 165.A O no hydrogen 3.290 N/A ALA 214.A N MET 224.A O no hydrogen 2.666 N/A TYR 216.A N GLU 219.A OE2 no hydrogen 3.053 N/A GLU 219.A N TYR 216.A O no hydrogen 2.897 N/A GLY 221.A N SER 158.A OG no hydrogen 2.785 N/A ILE 223.A N LEU 151.A O no hydrogen 3.423 N/A MET 224.A N ASN 215.A OD1 no hydrogen 3.529 N/A LEU 225.A N LEU 149.A O no hydrogen 3.363 N/A ASN 226.A ND2 TYR 318.A OH no hydrogen 3.417 N/A VAL 227.A N LYS 147.A O no hydrogen 3.371 N/A ILE 229.A N PHE 145.A O no hydrogen 3.251 N/A ALA 230.A N SER 245.A OG no hydrogen 2.997 N/A THR 231.A N ILE 229.A O no hydrogen 3.151 N/A ASN 236.A N PRO 233.A O no hydrogen 2.887 N/A VAL 239.A N ASN 236.A O no hydrogen 3.501 N/A GLY 242.A N ALA 230.A O no hydrogen 2.960 N/A SER 246.A N GLY 242.A O no hydrogen 3.385 N/A SER 246.A OG TYR 178.A OH no hydrogen 2.746 N/A SER 246.A OG GLY 242.A O no hydrogen 2.685 N/A TYR 247.A N GLN 243.A O no hydrogen 3.473 N/A ILE 248.A N MET 244.A O no hydrogen 2.942 N/A TRP 249.A N SER 245.A O no hydrogen 3.046 N/A TRP 249.A NE1 VAL 227.A O no hydrogen 2.811 N/A SER 250.A N SER 246.A O no hydrogen 3.121 N/A SER 250.A N TYR 247.A O no hydrogen 2.959 N/A SER 250.A OG TYR 247.A O no hydrogen 2.480 N/A LEU 251.A N ILE 248.A O no hydrogen 3.068 N/A LYS 252.A N ASP 255.A OD2 no hydrogen 2.946 N/A LYS 252.A NZ ASP 180.A O no hydrogen 2.851 N/A LYS 252.A NZ ASP 182.A OD2 no hydrogen 3.319 N/A GLY 254.A N VAL 136.A O no hydrogen 3.390 N/A ASP 255.A N LYS 252.A O no hydrogen 3.016 N/A LYS 256.A NZ GLU 133.A OE2 no hydrogen 2.289 N/A CYS 257.A N CYS 134.A O no hydrogen 2.851 N/A ILE 259.A N TRP 132.A O no hydrogen 2.585 N/A SER 260.A N GLN 168.A O no hydrogen 2.655 N/A PHE 263.A N TYR 166.A O no hydrogen 3.016 N/A PHE 267.A N GLU 265.A O no hydrogen 2.821 N/A LYS 269.A N TYR 375.A OH no hydrogen 2.769 N/A LYS 269.A NZ GLU 398.A O no hydrogen 2.222 N/A LYS 269.A NZ ASN 399.A OD1 no hydrogen 3.290 N/A THR 271.A OG1 GLU 373.A OE2 no hydrogen 2.443 N/A ALA 273.A N THR 271.A OG1 no hydrogen 3.379 N/A MET 275.A N LYS 303.A O no hydrogen 2.928 N/A VAL 276.A N GLU 373.A O no hydrogen 2.887 N/A PHE 277.A N SER 305.A O no hydrogen 2.797 N/A ILE 278.A N TYR 375.A O no hydrogen 2.924 N/A GLY 279.A N TRP 307.A O no hydrogen 2.722 N/A GLY 280.A N CYS 377.A O no hydrogen 3.039 N/A GLY 283.A N GLY 280.A O no hydrogen 2.917 N/A MET 284.A N GLY 281.A O no hydrogen 3.298 N/A ALA 285.A N ALA 282.A O no hydrogen 3.171 N/A MET 287.A N GLY 283.A O no hydrogen 3.415 N/A ARG 288.A N MET 284.A O no hydrogen 2.699 N/A ARG 288.A NH1 ALA 214.A O no hydrogen 2.864 N/A ARG 288.A NH1 GLU 219.A OE2 no hydrogen 3.212 N/A ARG 288.A NH2 GLU 219.A OE1 no hydrogen 3.003 N/A SER 289.A N ALA 285.A O no hydrogen 2.974 N/A SER 289.A OG ASN 215.A O no hydrogen 2.663 N/A HIS 290.A N PRO 286.A O no hydrogen 2.961 N/A ILE 291.A N MET 287.A O no hydrogen 2.931 N/A PHE 292.A N ARG 288.A O no hydrogen 2.935 N/A ASP 293.A N SER 289.A O no hydrogen 3.030 N/A GLN 294.A N HIS 290.A O no hydrogen 3.022 N/A LEU 295.A N ILE 291.A O no hydrogen 3.041 N/A LYS 296.A N PHE 292.A O no hydrogen 2.752 N/A ARG 297.A N ASP 293.A O no hydrogen 3.026 N/A ARG 297.A NE ASP 293.A OD1 no hydrogen 2.474 N/A ARG 297.A NE ASP 293.A OD2 no hydrogen 3.344 N/A ARG 297.A NH2 ASP 293.A OD2 no hydrogen 2.806 N/A LEU 298.A N ASP 293.A O no hydrogen 2.797 N/A SER 300.A N GLN 294.A O no hydrogen 2.786 N/A ARG 302.A N SER 300.A OG no hydrogen 3.205 N/A ARG 302.A NE ALA 273.A O no hydrogen 2.497 N/A ARG 302.A NH1 LYS 269.A O no hydrogen 3.096 N/A ARG 302.A NH2 ALA 273.A O no hydrogen 2.653 N/A ARG 302.A NH2 GLU 373.A OE1 no hydrogen 2.792 N/A MET 304.A N ASN 331.A O no hydrogen 2.714 N/A SER 305.A N MET 275.A O no hydrogen 3.251 N/A TYR 306.A N VAL 333.A O no hydrogen 3.238 N/A TRP 307.A N PHE 277.A O no hydrogen 2.737 N/A TRP 307.A NE1 SER 305.A OG no hydrogen 2.848 N/A TYR 308.A N HIS 335.A O no hydrogen 3.027 N/A TYR 308.A OH GLY 281.A O no hydrogen 2.912 N/A GLY 309.A N GLY 279.A O no hydrogen 3.033 N/A ALA 310.A N ALA 337.A O no hydrogen 2.950 N/A ARG 311.A NH2 ASP 190.A OD2 no hydrogen 2.519 N/A LYS 313.A N ASP 345.A OD2 no hydrogen 3.273 N/A ARG 314.A NE THR 144.A OG1 no hydrogen 2.975 N/A GLU 315.A N SER 312.A O no hydrogen 2.995 N/A MET 316.A N LYS 313.A O no hydrogen 2.999 N/A TYR 318.A OH GLU 148.A OE2 no hydrogen 2.850 N/A GLU 320.A N GLU 320.A OE1 no hydrogen 2.674 N/A PHE 322.A N TYR 318.A O no hydrogen 3.011 N/A ASP 323.A N VAL 319.A O no hydrogen 2.906 N/A GLY 324.A N GLU 320.A O no hydrogen 2.875 N/A LEU 325.A N ASP 321.A O no hydrogen 3.186 N/A ALA 326.A N PHE 322.A O no hydrogen 2.942 N/A ALA 327.A N ASP 323.A O no hydrogen 3.127 N/A GLU 328.A N GLY 324.A O no hydrogen 3.172 N/A ASN 329.A ND2 LEU 325.A O no hydrogen 2.911 N/A ASN 331.A ND2 SER 300.A O no hydrogen 3.210 N/A ASN 331.A ND2 ARG 302.A O no hydrogen 2.414 N/A PHE 332.A N ASN 329.A O no hydrogen 3.350 N/A VAL 333.A N MET 304.A O no hydrogen 3.266 N/A TRP 334.A NE1 ASP 323.A OD1 no hydrogen 3.046 N/A HIS 335.A N TYR 306.A O no hydrogen 2.902 N/A CYS 336.A SG TYR 308.A O no hydrogen 3.120 N/A CYS 336.A SG ALA 337.A O no hydrogen 3.780 N/A ALA 337.A N TYR 308.A O no hydrogen 2.760 N/A LEU 338.A N TYR 350.A O no hydrogen 3.426 N/A SER 339.A N ALA 310.A O no hydrogen 2.899 N/A SER 339.A OG ALA 310.A O no hydrogen 3.554 N/A ASP 340.A N ARG 311.A O no hydrogen 3.008 N/A GLN 342.A N ASP 345.A OD2 no hydrogen 2.874 N/A GLN 342.A NE2 ASP 340.A O no hydrogen 3.319 N/A GLU 344.A N GLU 344.A OE2 no hydrogen 2.635 N/A ASP 345.A N GLN 342.A O no hydrogen 2.959 N/A TRP 347.A NE1 TYR 350.A O no hydrogen 2.567 N/A GLY 352.A N LEU 338.A O no hydrogen 3.104 N/A VAL 357.A N PHE 353.A O no hydrogen 3.030 N/A LEU 358.A N ILE 354.A O no hydrogen 2.827 N/A TYR 359.A N HIS 355.A O no hydrogen 3.295 N/A GLU 360.A N ASN 356.A O no hydrogen 2.866 N/A ASN 361.A N VAL 357.A O no hydrogen 2.947 N/A ASN 361.A ND2 VAL 357.A O no hydrogen 2.738 N/A TYR 362.A N LEU 358.A O no hydrogen 3.021 N/A TYR 362.A N TYR 359.A O no hydrogen 3.430 N/A TYR 362.A OH GLU 274.A OE2 no hydrogen 2.227 N/A LEU 363.A N LEU 358.A O no hydrogen 2.965 N/A LYS 364.A N TYR 359.A O no hydrogen 2.779 N/A LYS 364.A NZ GLU 360.A OE2 no hydrogen 2.712 N/A HIS 366.A N LEU 363.A O no hydrogen 3.082 N/A HIS 366.A NE2 GLU 274.A OE1 no hydrogen 2.839 N/A ALA 368.A N HIS 366.A ND1 no hydrogen 2.941 N/A GLU 370.A N GLU 370.A OE1 no hydrogen 2.705 N/A ASP 371.A N ALA 368.A O no hydrogen 2.967 N/A CYS 372.A N PRO 369.A O no hydrogen 3.212 N/A CYS 372.A SG HIS 366.A NE2 no hydrogen 3.317 N/A GLU 373.A N GLU 274.A O no hydrogen 2.726 N/A TYR 374.A N ASN 399.A O no hydrogen 2.928 N/A TYR 374.A OH PRO 369.A O no hydrogen 2.825 N/A TYR 375.A N VAL 276.A O no hydrogen 3.049 N/A TYR 375.A OH GLU 373.A OE1 no hydrogen 2.659 N/A MET 376.A N LEU 401.A O no hydrogen 3.001 N/A CYS 377.A N ILE 278.A O no hydrogen 3.015 N/A CYS 377.A SG ASP 403.A O no hydrogen 3.648 N/A ASN 383.A N PRO 379.A O no hydrogen 2.853 N/A ASN 383.A ND2 GLY 378.A O no hydrogen 2.850 N/A ALA 384.A N PRO 380.A O no hydrogen 2.842 N/A ALA 385.A N MET 381.A O no hydrogen 2.800 N/A VAL 386.A N MET 382.A O no hydrogen 2.703 N/A ILE 387.A N ASN 383.A O no hydrogen 2.800 N/A ASN 388.A N ALA 384.A O no hydrogen 2.855 N/A MET 389.A N ALA 385.A O no hydrogen 2.928 N/A LEU 390.A N VAL 386.A O no hydrogen 2.761 N/A LYS 391.A N ILE 387.A O no hydrogen 2.943 N/A ASN 392.A N ASN 388.A O no hydrogen 3.025 N/A ASN 392.A ND2 ASN 388.A OD1 no hydrogen 3.385 N/A LEU 393.A N MET 389.A O no hydrogen 3.008 N/A GLY 394.A N LYS 391.A O no hydrogen 3.128 N/A VAL 395.A N LEU 390.A O no hydrogen 3.099 N/A ASN 399.A N GLU 396.A O no hydrogen 2.876 N/A ILE 400.A N GLU 397.A O no hydrogen 3.288 N/A LEU 401.A N TYR 374.A O no hydrogen 2.721 N/A ASP 403.A N MET 376.A O no hydrogen 3.026 N/A GLY 406.A N ASP 404.A OD1 no hydrogen 3.007 N/A