Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4p6w_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLN 2.A NE2 THR 4.A O no hydrogen 2.897 N/A GLN 2.A NE2 THR 4.A OG1 no hydrogen 3.346 N/A VAL 8.A N GLU 171.A OE2 no hydrogen 3.139 N/A SER 9.A N THR 6.A O no hydrogen 3.199 N/A SER 9.A N THR 6.A OG1 no hydrogen 3.102 N/A SER 9.A OG THR 6.A O no hydrogen 2.594 N/A SER 9.A OG THR 6.A OG1 no hydrogen 3.330 N/A LEU 11.A N LEU 7.A O no hydrogen 2.979 N/A GLU 12.A N VAL 8.A O no hydrogen 2.981 N/A VAL 13.A N LEU 10.A O no hydrogen 2.909 N/A ILE 14.A N LEU 10.A O no hydrogen 3.080 N/A ALA 21.A N ASP 101.A OD1 no hydrogen 2.846 N/A GLY 22.A N ASP 101.A OD2 no hydrogen 2.643 N/A TYR 23.A N ASP 101.A OD2 no hydrogen 3.334 N/A TYR 23.A OH ASP 29.A OD1 no hydrogen 2.493 N/A SER 26.A N ASP 24.A OD1 no hydrogen 3.172 N/A SER 26.A OG ASP 24.A OD1 no hydrogen 2.707 N/A SER 26.A OG ASP 24.A OD2 no hydrogen 3.431 N/A THR 31.A OG1 PRO 112.A O no hydrogen 2.667 N/A ARG 33.A N SER 30.A OG no hydrogen 3.054 N/A ARG 33.A NH1 ASP 24.A O no hydrogen 2.663 N/A ARG 33.A NH2 ASP 24.A O no hydrogen 3.199 N/A ARG 33.A NH2 PRO 28.A O no hydrogen 2.983 N/A ILE 34.A N SER 30.A O no hydrogen 3.147 N/A MET 35.A N THR 31.A O no hydrogen 2.918 N/A THR 36.A N TRP 32.A O no hydrogen 3.010 N/A THR 36.A OG1 TRP 32.A O no hydrogen 3.215 N/A THR 37.A N ARG 33.A O no hydrogen 3.011 N/A THR 37.A OG1 ARG 33.A O no hydrogen 2.809 N/A LEU 38.A N ILE 34.A O no hydrogen 2.883 N/A ASN 39.A N MET 35.A O no hydrogen 2.874 N/A ASN 39.A ND2 GLU 223.A O no hydrogen 3.000 N/A MET 40.A N THR 36.A O no hydrogen 3.016 N/A LEU 41.A N THR 37.A O no hydrogen 3.007 N/A GLY 42.A N LEU 38.A O no hydrogen 2.720 N/A GLY 43.A N ASN 39.A O no hydrogen 2.952 N/A ARG 44.A N MET 40.A O no hydrogen 3.316 N/A ARG 44.A NH1 TYR 20.A O no hydrogen 2.958 N/A ARG 44.A NH2 TYR 20.A O no hydrogen 3.275 N/A GLN 45.A N LEU 41.A O no hydrogen 2.918 N/A VAL 46.A N GLY 42.A O no hydrogen 2.877 N/A ILE 47.A N GLY 43.A O no hydrogen 3.091 N/A ALA 48.A N ARG 44.A O no hydrogen 3.027 N/A ALA 49.A N GLN 45.A O no hydrogen 2.890 N/A VAL 50.A N VAL 46.A O no hydrogen 3.050 N/A VAL 50.A N ILE 47.A O no hydrogen 3.169 N/A LYS 51.A N ILE 47.A O no hydrogen 3.451 N/A TRP 52.A N ALA 48.A O no hydrogen 3.044 N/A ALA 53.A N ALA 49.A O no hydrogen 2.804 N/A LYS 54.A N VAL 50.A O no hydrogen 3.013 N/A ALA 55.A N TRP 52.A O no hydrogen 2.965 N/A ILE 56.A N ALA 53.A O no hydrogen 3.003 N/A PHE 59.A N ILE 56.A O no hydrogen 2.969 N/A ASN 61.A N GLY 58.A O no hydrogen 2.956 N/A LEU 62.A N PHE 59.A O no hydrogen 3.130 N/A HIS 63.A N SER 157.A OG no hydrogen 2.912 N/A ASP 65.A N HIS 63.A ND1 no hydrogen 2.910 N/A GLN 67.A N HIS 63.A O no hydrogen 3.022 N/A GLN 67.A NE2 LEU 62.A O no hydrogen 2.997 N/A MET 68.A N LEU 64.A O no hydrogen 3.030 N/A THR 69.A N ASP 65.A O no hydrogen 2.913 N/A THR 69.A OG1 ASP 65.A O no hydrogen 2.710 N/A LEU 70.A N ASP 66.A O no hydrogen 2.909 N/A LEU 71.A N GLN 67.A O no hydrogen 3.329 N/A GLN 72.A N MET 68.A O no hydrogen 2.959 N/A TYR 73.A N THR 69.A O no hydrogen 3.002 N/A TYR 73.A OH ASN 243.A O no hydrogen 2.537 N/A SER 74.A N LEU 70.A O no hydrogen 3.094 N/A SER 74.A OG LEU 70.A O no hydrogen 2.741 N/A LEU 78.A N SER 74.A O no hydrogen 2.863 N/A MET 79.A N TRP 75.A O no hydrogen 2.917 N/A ALA 80.A N MET 76.A O no hydrogen 2.840 N/A PHE 81.A N ALA 77.A O no hydrogen 2.955 N/A ALA 82.A N LEU 78.A O no hydrogen 3.123 N/A LEU 83.A N MET 79.A O no hydrogen 3.002 N/A GLY 84.A N ALA 80.A O no hydrogen 2.911 N/A TRP 85.A N PHE 81.A O no hydrogen 2.946 N/A ARG 86.A N ALA 82.A O no hydrogen 2.980 N/A ARG 86.A NE TYR 97.A O no hydrogen 3.046 N/A SER 87.A N LEU 83.A O no hydrogen 3.001 N/A SER 87.A OG LEU 83.A O no hydrogen 2.811 N/A SER 87.A OG LEU 95.A O no hydrogen 3.566 N/A TYR 88.A N GLY 84.A O no hydrogen 2.859 N/A ARG 89.A N TRP 85.A O no hydrogen 2.863 N/A GLN 90.A N ARG 86.A O no hydrogen 2.930 N/A SER 91.A N SER 87.A O no hydrogen 3.459 N/A SER 91.A OG ALA 93.A O no hydrogen 3.101 N/A LEU 96.A N ILE 104.A O no hydrogen 2.940 N/A TYR 97.A N SER 87.A OG no hydrogen 2.964 N/A ALA 99.A N LEU 102.A O no hydrogen 3.377 N/A LEU 102.A N ALA 99.A O no hydrogen 2.992 N/A ILE 104.A N LEU 96.A O no hydrogen 2.932 N/A ARG 108.A N ASN 105.A OD1 no hydrogen 2.999 N/A ARG 108.A NE ASP 29.A OD2 no hydrogen 2.890 N/A ARG 108.A NH1 ILE 103.A O no hydrogen 2.919 N/A ARG 108.A NH2 ASP 29.A OD1 no hydrogen 3.040 N/A ARG 108.A NH2 ASP 29.A OD2 no hydrogen 3.328 N/A MET 109.A N ASN 105.A O no hydrogen 3.169 N/A THR 110.A N GLN 107.A O no hydrogen 2.948 N/A THR 110.A OG1 GLN 107.A O no hydrogen 2.533 N/A THR 110.A OG1 GLN 107.A OE1 no hydrogen 3.288 N/A LEU 111.A N ARG 108.A O no hydrogen 3.142 N/A MET 114.A N LEU 111.A O no hydrogen 3.307 N/A GLN 117.A NE2 CYS 113.A O no hydrogen 2.898 N/A CYS 118.A N MET 114.A O no hydrogen 3.118 N/A CYS 118.A SG MET 114.A O no hydrogen 3.115 N/A LYS 119.A N TYR 115.A O no hydrogen 3.000 N/A HIS 120.A N ASP 116.A O no hydrogen 3.180 N/A MET 121.A N GLN 117.A O no hydrogen 3.085 N/A LEU 122.A N CYS 118.A O no hydrogen 2.766 N/A TYR 123.A N LYS 119.A O no hydrogen 3.175 N/A TYR 123.A OH SER 199.A OG no hydrogen 3.139 N/A VAL 124.A N MET 121.A O no hydrogen 3.240 N/A SER 125.A OG LEU 122.A O no hydrogen 2.886 N/A SER 126.A N LEU 122.A O no hydrogen 2.889 N/A GLU 127.A N TYR 123.A O no hydrogen 2.927 N/A LEU 128.A N VAL 124.A O no hydrogen 3.016 N/A HIS 129.A N SER 125.A O no hydrogen 3.048 N/A ARG 130.A N SER 126.A O no hydrogen 2.898 N/A ARG 130.A NE GLU 127.A OE2 no hydrogen 2.922 N/A ARG 130.A NH2 GLU 127.A OE1 no hydrogen 2.869 N/A ARG 130.A NH2 GLU 127.A OE2 no hydrogen 3.554 N/A LEU 131.A N GLU 127.A O no hydrogen 2.966 N/A GLN 132.A N HIS 129.A O no hydrogen 3.197 N/A GLN 132.A NE2 HIS 129.A O no hydrogen 2.922 N/A VAL 133.A N LEU 128.A O no hydrogen 3.102 N/A SER 134.A N GLU 137.A OE1 no hydrogen 2.868 N/A GLU 137.A N SER 134.A OG no hydrogen 3.147 N/A TYR 138.A N SER 134.A O no hydrogen 2.855 N/A LEU 139.A N TYR 135.A O no hydrogen 2.958 N/A CYS 140.A N GLU 136.A O no hydrogen 3.238 N/A CYS 140.A SG GLU 136.A O no hydrogen 3.407 N/A MET 141.A N GLU 137.A O no hydrogen 2.926 N/A LYS 142.A N TYR 138.A O no hydrogen 2.872 N/A LYS 142.A NZ GLU 15.A OE1 no hydrogen 2.786 N/A LYS 142.A NZ GLU 15.A OE2 no hydrogen 3.450 N/A VAL 143.A N LEU 139.A O no hydrogen 3.328 N/A LEU 144.A N CYS 140.A O no hydrogen 3.153 N/A LEU 145.A N MET 141.A O no hydrogen 3.011 N/A LEU 146.A N LYS 142.A O no hydrogen 3.317 N/A LEU 147.A N VAL 143.A O no hydrogen 3.205 N/A LEU 147.A N LEU 144.A O no hydrogen 3.017 N/A SER 148.A N LEU 145.A O no hydrogen 3.160 N/A SER 148.A OG LEU 145.A O no hydrogen 2.624 N/A ILE 150.A N LYS 245.A O no hydrogen 3.065 N/A LYS 152.A N ASN 243.A OD1 no hydrogen 3.065 N/A LYS 152.A NZ ASP 153.A OD1 no hydrogen 3.497 N/A GLY 154.A N PRO 151.A O no hydrogen 2.913 N/A LEU 155.A N GLN 158.A OE1 no hydrogen 2.882 N/A LYS 156.A N ASP 66.A OD1 no hydrogen 2.963 N/A LYS 156.A NZ ASP 65.A OD2 no hydrogen 2.790 N/A SER 157.A N ASP 66.A OD2 no hydrogen 2.647 N/A SER 157.A OG ASP 66.A OD2 no hydrogen 3.284 N/A GLN 158.A NE2 ASP 162.A OD2 no hydrogen 2.968 N/A PHE 161.A N SER 157.A O no hydrogen 2.959 N/A ASP 162.A N GLN 158.A O no hydrogen 2.926 N/A GLU 163.A N GLU 159.A O no hydrogen 3.186 N/A ILE 164.A N LEU 160.A O no hydrogen 2.979 N/A ARG 165.A N PHE 161.A O no hydrogen 2.887 N/A ARG 165.A NE LEU 147.A O no hydrogen 2.900 N/A MET 166.A N ASP 162.A O no hydrogen 2.941 N/A THR 167.A N GLU 163.A O no hydrogen 3.029 N/A THR 167.A OG1 GLU 163.A O no hydrogen 2.817 N/A TYR 168.A N ILE 164.A O no hydrogen 3.208 N/A TYR 168.A N ARG 165.A O no hydrogen 3.213 N/A ILE 169.A N ARG 165.A O no hydrogen 3.070 N/A LYS 170.A N MET 166.A O no hydrogen 2.994 N/A GLU 171.A N THR 167.A O no hydrogen 2.948 N/A LEU 172.A N TYR 168.A O no hydrogen 2.848 N/A GLY 173.A N ILE 169.A O no hydrogen 3.138 N/A ALA 174.A N LYS 170.A O no hydrogen 2.978 N/A ALA 175.A N GLU 171.A O no hydrogen 2.947 N/A ILE 176.A N LEU 172.A O no hydrogen 3.052 N/A VAL 177.A N GLY 173.A O no hydrogen 3.102 N/A ALA 178.A N ALA 174.A O no hydrogen 2.846 N/A ARG 179.A N ALA 175.A O no hydrogen 2.890 N/A ARG 179.A N ILE 176.A O no hydrogen 3.273 N/A ARG 179.A NE GLN 132.A O no hydrogen 3.438 N/A ARG 179.A NH2 GLN 132.A O no hydrogen 3.340 N/A SER 184.A OG ASN 182.A OD1 no hydrogen 3.367 N/A GLN 185.A N ASN 182.A O no hydrogen 3.373 N/A ASN 186.A N SER 183.A O no hydrogen 3.222 N/A ARG 189.A N GLN 185.A O no hydrogen 2.980 N/A ARG 189.A NE GLU 137.A OE2 no hydrogen 2.654 N/A ARG 189.A NH1 LEU 131.A O no hydrogen 2.821 N/A ARG 189.A NH2 LEU 131.A O no hydrogen 2.847 N/A ARG 189.A NH2 GLU 137.A OE1 no hydrogen 2.772 N/A ARG 189.A NH2 GLU 137.A OE2 no hydrogen 3.459 N/A PHE 190.A N ASN 186.A O no hydrogen 2.874 N/A TYR 191.A N TRP 187.A O no hydrogen 3.190 N/A GLN 192.A N GLN 188.A O no hydrogen 2.993 N/A LEU 193.A N ARG 189.A O no hydrogen 2.844 N/A THR 194.A N PHE 190.A O no hydrogen 3.097 N/A THR 194.A OG1 PHE 190.A O no hydrogen 2.812 N/A THR 194.A OG1 TYR 191.A O no hydrogen 3.096 N/A THR 194.A OG1 HIS 250.A NE2 no hydrogen 2.818 N/A LYS 195.A N TYR 191.A O no hydrogen 2.790 N/A LEU 196.A N GLN 192.A O no hydrogen 2.995 N/A LEU 197.A N LEU 193.A O no hydrogen 3.089 N/A ASP 198.A N THR 194.A O no hydrogen 3.065 N/A SER 199.A N LYS 195.A O no hydrogen 3.040 N/A SER 199.A OG TYR 123.A OH no hydrogen 3.139 N/A SER 199.A OG LEU 196.A O no hydrogen 2.771 N/A MET 200.A N LEU 196.A O no hydrogen 3.151 N/A MET 200.A N LEU 197.A O no hydrogen 3.218 N/A HIS 201.A N ASP 198.A O no hydrogen 3.221 N/A GLU 202.A N SER 199.A O no hydrogen 3.071 N/A VAL 203.A N SER 199.A O no hydrogen 3.163 N/A VAL 204.A N MET 200.A O no hydrogen 2.861 N/A GLU 205.A N HIS 201.A O no hydrogen 2.967 N/A ASN 206.A N GLU 202.A O no hydrogen 3.048 N/A LEU 207.A N VAL 203.A O no hydrogen 3.077 N/A LEU 208.A N VAL 204.A O no hydrogen 2.820 N/A ASN 209.A N GLU 205.A O no hydrogen 3.158 N/A TYR 210.A N ASN 206.A O no hydrogen 3.253 N/A CYS 211.A N LEU 207.A O no hydrogen 2.897 N/A PHE 212.A N LEU 208.A O no hydrogen 2.767 N/A GLN 213.A N ASN 209.A O no hydrogen 3.079 N/A THR 214.A N TYR 210.A O no hydrogen 2.927 N/A THR 214.A OG1 TYR 210.A O no hydrogen 2.943 N/A PHE 215.A N CYS 211.A O no hydrogen 2.876 N/A LEU 216.A N PHE 212.A O no hydrogen 3.011 N/A LEU 216.A N GLN 213.A O no hydrogen 3.267 N/A ASP 217.A N THR 214.A O no hydrogen 3.152 N/A THR 219.A N ASP 217.A OD2 no hydrogen 2.939 N/A THR 219.A OG1 ASP 217.A OD1 no hydrogen 3.079 N/A THR 219.A OG1 ASP 217.A OD2 no hydrogen 2.697 N/A GLU 223.A N THR 36.A OG1 no hydrogen 3.165 N/A ALA 229.A N PRO 225.A O no hydrogen 3.020 N/A GLU 230.A N GLU 226.A O no hydrogen 2.940 N/A ILE 231.A N MET 227.A O no hydrogen 3.315 N/A ILE 232.A N LEU 228.A O no hydrogen 2.813 N/A THR 233.A N ALA 229.A O no hydrogen 3.026 N/A THR 233.A OG1 ALA 229.A O no hydrogen 2.687 N/A ASN 234.A N GLU 230.A O no hydrogen 3.077 N/A GLN 235.A N ILE 231.A O no hydrogen 2.967 N/A GLN 235.A N ILE 232.A O no hydrogen 3.214 N/A GLN 235.A NE2 ASN 234.A OD1 no hydrogen 3.043 N/A ILE 236.A N ILE 232.A O no hydrogen 3.069 N/A LYS 238.A NZ ASN 234.A OD1 no hydrogen 2.897 N/A TYR 239.A N GLN 235.A O no hydrogen 3.159 N/A SER 240.A N ILE 236.A O no hydrogen 3.286 N/A ASN 241.A N PRO 237.A O no hydrogen 2.732 N/A ASN 243.A N LYS 238.A O no hydrogen 2.906 N/A ILE 244.A N GLY 242.A O no hydrogen 2.908 N/A LYS 245.A N ILE 150.A O no hydrogen 2.806 N/A LYS 245.A NZ LYS 152.A O no hydrogen 2.922 N/A LEU 247.A N SER 148.A O no hydrogen 2.885 N/A PHE 249.A N ASP 198.A OD1 no hydrogen 2.843 N/A HIS 250.A N ASP 198.A OD2 no hydrogen 2.865 N/A HIS 250.A NE2 THR 194.A OG1 no hydrogen 2.818 N/A