Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4q7i_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 2.A ND2 TYR 239.A O no hydrogen 3.592 N/A LYS 3.A NZ THR 62.A OG1 no hydrogen 2.934 N/A VAL 4.A N ASP 32.A OD2 no hydrogen 2.872 N/A GLY 5.A N ILE 243.A O no hydrogen 2.765 N/A MET 6.A N LEU 33.A O no hydrogen 3.143 N/A PHE 7.A N MET 245.A O no hydrogen 2.963 N/A TYR 8.A N GLU 35.A O no hydrogen 2.979 N/A TYR 8.A OH TRP 15.A O no hydrogen 2.613 N/A TYR 10.A N PHE 7.A O no hydrogen 3.218 N/A TYR 10.A OH MET 274.A O.A no hydrogen 2.646 N/A TYR 10.A OH MET 274.A O.B no hydrogen 2.642 N/A SER 12.A OG GLU 14.A O no hydrogen 2.819 N/A GLU 14.A N SER 12.A OG no hydrogen 3.004 N/A ALA 21.A N ASP 18.A OD1 no hydrogen 3.100 N/A THR 22.A N ASP 18.A O no hydrogen 2.997 N/A THR 22.A OG1 ASP 18.A O no hydrogen 2.794 N/A ALA 23.A N PHE 19.A O no hydrogen 2.890 N/A LYS 24.A N PRO 20.A O no hydrogen 2.980 N/A ARG 25.A N ALA 21.A O no hydrogen 3.035 N/A ARG 25.A NE ASP 275.A OD1 no hydrogen 2.882 N/A ARG 25.A NE ASP 275.A OD2 no hydrogen 3.371 N/A ARG 25.A NH2 GLU 272.A OE2 no hydrogen 3.264 N/A ARG 25.A NH2 ASP 275.A OD1 no hydrogen 3.407 N/A ARG 25.A NH2 ASP 275.A OD2 no hydrogen 2.828 N/A ILE 26.A N THR 22.A O no hydrogen 3.010 N/A ALA 27.A N ALA 23.A O no hydrogen 2.910 N/A GLY 28.A N LYS 24.A O no hydrogen 2.945 N/A LEU 29.A N ARG 25.A O no hydrogen 3.241 N/A LEU 29.A N ILE 26.A O no hydrogen 3.148 N/A GLY 30.A N ALA 27.A O no hydrogen 2.905 N/A ASP 32.A N VAL 4.A O no hydrogen 3.066 N/A MET 34.A N THR 62.A O no hydrogen 2.953 N/A GLU 35.A N MET 6.A O no hydrogen 3.204 N/A ILE 36.A N MET 64.A O no hydrogen 2.883 N/A LEU 38.A N CYS 66.A O no hydrogen 2.942 N/A GLY 39.A N SER 37.A OG no hydrogen 3.220 N/A HIS 42.A N LEU 38.A O no hydrogen 2.941 N/A HIS 42.A ND1 ASP 96.A OD2 no hydrogen 2.760 N/A ASN 43.A N GLU 40.A O no hydrogen 2.952 N/A LEU 44.A N PHE 41.A O no hydrogen 3.012 N/A LYS 48.A N SER 45.A OG no hydrogen 3.096 N/A LYS 48.A NZ GLU 51.A OE1 no hydrogen 2.934 N/A LYS 49.A N SER 45.A O no hydrogen 3.021 N/A LYS 49.A NZ HIS 42.A O no hydrogen 2.917 N/A LYS 49.A NZ ASP 96.A OD1 no hydrogen 2.889 N/A LYS 49.A NZ ASP 96.A OD2 no hydrogen 3.444 N/A ARG 50.A N ASP 46.A O no hydrogen 2.899 N/A ARG 50.A NH1 ARG 50.A O no hydrogen 3.162 N/A GLU 51.A N ALA 47.A O no hydrogen 2.885 N/A LEU 52.A N LYS 48.A O no hydrogen 3.279 N/A LYS 53.A N LYS 49.A O no hydrogen 3.330 N/A LYS 53.A NZ ASP 57.A OD1 no hydrogen 3.451 N/A LYS 53.A NZ ASP 57.A OD2 no hydrogen 2.679 N/A ALA 54.A N ARG 50.A O no hydrogen 2.938 N/A VAL 55.A N GLU 51.A O no hydrogen 3.114 N/A ALA 56.A N LEU 52.A O no hydrogen 2.919 N/A ASP 57.A N LYS 53.A O no hydrogen 2.866 N/A ASP 58.A N ALA 54.A O no hydrogen 3.019 N/A LEU 59.A N VAL 55.A O no hydrogen 3.045 N/A GLY 60.A N ASP 57.A O no hydrogen 3.155 N/A LEU 61.A N ALA 56.A O no hydrogen 2.945 N/A THR 62.A N ASP 32.A O no hydrogen 2.982 N/A MET 64.A N MET 34.A O no hydrogen 2.945 N/A CYS 65.A N VAL 104.A O no hydrogen 3.188 N/A CYS 66.A N ILE 36.A O no hydrogen 2.785 N/A CYS 66.A SG ILE 36.A O no hydrogen 3.601 N/A ILE 67.A N ALA 106.A O no hydrogen 3.027 N/A LEU 69.A N LEU 108.A O no hydrogen 3.354 N/A GLU 72.A N GLU 72.A OE2.B no hydrogen 2.425 N/A TYR 73.A N LYS 70.A O no hydrogen 2.831 N/A ASP 74.A N SER 71.A O no hydrogen 3.179 N/A ALA 76.A N ASP 74.A OD1 no hydrogen 2.983 N/A SER 77.A N ASP 74.A O no hydrogen 3.038 N/A ASP 79.A N SER 77.A OG no hydrogen 3.053 N/A LYS 80.A NZ ASP 84.A OD1 no hydrogen 2.768 N/A LYS 80.A NZ ASP 84.A OD2 no hydrogen 2.740 N/A SER 81.A N ASP 79.A OD1 no hydrogen 2.948 N/A VAL 82.A N ASP 79.A O no hydrogen 2.976 N/A ARG 83.A N ASP 79.A O no hydrogen 3.123 N/A ARG 83.A NH2 SER 77.A O no hydrogen 2.721 N/A ASP 84.A N LYS 80.A O no hydrogen 2.729 N/A ALA 85.A N SER 81.A O no hydrogen 3.043 N/A GLY 86.A N VAL 82.A O no hydrogen 2.888 N/A THR 87.A N.A ARG 83.A O no hydrogen 2.883 N/A THR 87.A N.B ARG 83.A O no hydrogen 2.870 N/A THR 87.A OG1.A ARG 83.A O no hydrogen 3.161 N/A THR 87.A OG1.A ASP 84.A O no hydrogen 3.226 N/A THR 87.A OG1.B ARG 83.A O no hydrogen 3.190 N/A THR 87.A OG1.B ASP 84.A O no hydrogen 3.243 N/A GLU 88.A N ASP 84.A O no hydrogen 3.126 N/A TYR 89.A N ALA 85.A O no hydrogen 2.909 N/A VAL 90.A N GLY 86.A O no hydrogen 2.889 N/A LYS 91.A N THR 87.A O.A no hydrogen 3.049 N/A LYS 91.A N THR 87.A O.B no hydrogen 3.043 N/A LYS 91.A NZ GLU 88.A OE2 no hydrogen 2.907 N/A ARG 92.A N GLU 88.A O no hydrogen 3.135 N/A LEU 93.A N TYR 89.A O no hydrogen 2.921 N/A LEU 94.A N VAL 90.A O no hydrogen 2.843 N/A ASP 95.A N LYS 91.A O no hydrogen 2.968 N/A ASP 96.A N ARG 92.A O no hydrogen 3.171 N/A CYS 97.A N LEU 93.A O no hydrogen 2.971 N/A CYS 97.A SG LEU 93.A O no hydrogen 3.444 N/A HIS 98.A N LEU 94.A O no hydrogen 2.880 N/A LEU 99.A N ASP 95.A O no hydrogen 3.044 N/A LEU 100.A N ASP 96.A O no hydrogen 3.001 N/A GLY 101.A N HIS 98.A O no hydrogen 3.114 N/A ALA 102.A N CYS 97.A O no hydrogen 2.879 N/A PHE 105.A N ILE 148.A O no hydrogen 2.757 N/A ALA 106.A N CYS 65.A O no hydrogen 2.886 N/A GLY 107.A N GLN 183.A OE1 no hydrogen 2.983 N/A THR 109.A OG1 GLY 107.A O no hydrogen 3.563 N/A THR 109.A OG1 ALA 150.A O no hydrogen 2.837 N/A TRP 113.A N LEU 69.A O no hydrogen 2.958 N/A TRP 113.A NE1 GLU 158.A OE1 no hydrogen 2.831 N/A GLN 115.A N GLU 158.A O no hydrogen 2.738 N/A GLN 115.A NE2 ASP 74.A OD2 no hydrogen 2.751 N/A MET 121.A N PRO 118.A O no hydrogen 2.934 N/A LYS 124.A NZ TRP 160.A O no hydrogen 2.928 N/A LYS 124.A NZ LEU 161.A O no hydrogen 3.180 N/A LYS 124.A NZ GLU 167.A OE2 no hydrogen 2.731 N/A ARG 125.A N ASP 123.A OD1 no hydrogen 3.210 N/A VAL 128.A N LYS 124.A O no hydrogen 2.959 N/A ASP 129.A N ARG 125.A O no hydrogen 2.805 N/A ARG 130.A N PRO 126.A O no hydrogen 3.067 N/A ARG 130.A NE ALA 76.A O no hydrogen 2.918 N/A ARG 130.A NH2 ALA 76.A O no hydrogen 3.507 N/A ALA 131.A N TYR 127.A O no hydrogen 2.998 N/A ILE 132.A N VAL 128.A O no hydrogen 2.936 N/A GLU 133.A N ASP 129.A O no hydrogen 3.014 N/A SER 134.A N ARG 130.A O no hydrogen 2.849 N/A SER 134.A OG PHE 75.A O no hydrogen 2.799 N/A SER 134.A OG ARG 130.A O no hydrogen 3.179 N/A VAL 135.A N ALA 131.A O no hydrogen 2.913 N/A ARG 136.A N ILE 132.A O no hydrogen 2.923 N/A ARG 136.A NH1 ALA 174.A O no hydrogen 3.484 N/A ARG 136.A NH1 VAL 175.A O no hydrogen 2.986 N/A ARG 137.A N GLU 133.A O no hydrogen 3.032 N/A ARG 137.A N SER 134.A O no hydrogen 3.015 N/A ARG 137.A NH1 ASP 84.A OD1 no hydrogen 2.900 N/A ARG 137.A NH2 ASP 84.A OD1 no hydrogen 2.632 N/A VAL 138.A N VAL 135.A O no hydrogen 2.988 N/A ILE 139.A N VAL 135.A O no hydrogen 2.948 N/A LYS 140.A NZ ASP 144.A OD2 no hydrogen 3.194 N/A VAL 141.A N VAL 138.A O no hydrogen 3.028 N/A GLU 143.A N ILE 139.A O no hydrogen 2.874 N/A ASP 144.A N LYS 140.A O no hydrogen 2.813 N/A TYR 145.A N VAL 141.A O no hydrogen 3.008 N/A TYR 145.A OH ASP 95.A OD1 no hydrogen 2.519 N/A GLY 146.A N GLU 143.A O no hydrogen 3.063 N/A ILE 147.A N ALA 142.A O no hydrogen 2.969 N/A ILE 148.A N PRO 103.A O no hydrogen 2.992 N/A TYR 149.A N ALA 179.A O no hydrogen 2.822 N/A TYR 149.A OH THR 109.A O no hydrogen 2.559 N/A ALA 150.A N PHE 105.A O no hydrogen 2.880 N/A LEU 151.A N LYS 181.A O no hydrogen 2.727 N/A GLU 152.A N GLY 107.A O no hydrogen 2.912 N/A VAL 153.A N GLN 183.A O no hydrogen 2.978 N/A ASN 155.A N HIS 188.A ND1 no hydrogen 3.086 N/A ASN 155.A ND2 HIS 188.A ND1 no hydrogen 2.923 N/A ARG 156.A N GLU 192.A OE2 no hydrogen 2.823 N/A ARG 156.A NE GLU 192.A OE1 no hydrogen 3.467 N/A ARG 156.A NE GLU 192.A OE2 no hydrogen 2.888 N/A ARG 156.A NH2 GLU 192.A OE1 no hydrogen 2.911 N/A TYR 157.A N ASN 155.A OD1 no hydrogen 2.882 N/A GLU 158.A N ASN 155.A O no hydrogen 2.994 N/A GLN 159.A N ASN 155.A O no hydrogen 3.323 N/A TRP 160.A NE1 GLN 115.A OE1 no hydrogen 2.771 N/A CYS 162.A SG GLU 167.A O no hydrogen 3.781 N/A ASN 163.A N GLU 167.A OE1 no hydrogen 2.742 N/A ASN 163.A ND2 VAL 154.A O no hydrogen 2.903 N/A ASN 163.A ND2 GLN 159.A O no hydrogen 2.971 N/A ALA 165.A N GLU 193.A OE2 no hydrogen 2.799 N/A GLU 167.A N ASP 164.A OD1 no hydrogen 2.951 N/A ALA 168.A N ASP 164.A O no hydrogen 3.085 N/A ILE 169.A N ALA 165.A O no hydrogen 2.767 N/A ALA 170.A N LYS 166.A O no hydrogen 3.011 N/A PHE 171.A N GLU 167.A O no hydrogen 3.066 N/A ALA 172.A N ALA 168.A O no hydrogen 2.822 N/A ASP 173.A N ILE 169.A O no hydrogen 2.751 N/A ALA 174.A N ALA 170.A O no hydrogen 3.123 N/A VAL 175.A N PHE 171.A O no hydrogen 3.004 N/A ASP 176.A N ALA 172.A O no hydrogen 2.990 N/A SER 177.A OG GLU 143.A OE2 no hydrogen 2.514 N/A ALA 179.A N SER 177.A OG no hydrogen 2.983 N/A CYS 180.A N SER 177.A O no hydrogen 3.079 N/A LYS 181.A N TYR 149.A O no hydrogen 2.944 N/A LYS 181.A NZ GLY 205.A O no hydrogen 3.050 N/A VAL 182.A N LYS 206.A O no hydrogen 2.784 N/A GLN 183.A N LEU 151.A O no hydrogen 2.914 N/A THR 186.A N HIS 211.A O no hydrogen 3.004 N/A THR 186.A OG1 GLY 213.A O no hydrogen 2.685 N/A PHE 187.A N ASP 185.A OD1 no hydrogen 3.015 N/A MET 189.A N ASP 185.A O no hydrogen 2.818 N/A ASN 190.A N THR 186.A O no hydrogen 2.991 N/A GLU 192.A N HIS 188.A O no hydrogen 3.042 N/A GLU 193.A N MET 189.A O no hydrogen 2.852 N/A ARG 197.A N GLU 229.A OE2 no hydrogen 2.960 N/A ARG 197.A NH1 GLU 236.A OE2 no hydrogen 2.731 N/A ASP 198.A N SER 195.A OG no hydrogen 2.982 N/A ALA 199.A N SER 195.A O no hydrogen 3.123 N/A ILE 200.A N PHE 196.A O no hydrogen 3.034 N/A LEU 201.A N ARG 197.A O no hydrogen 2.867 N/A ALA 202.A N ASP 198.A O no hydrogen 3.034 N/A CYS 203.A N ILE 200.A O no hydrogen 2.882 N/A CYS 203.A SG ALA 199.A O no hydrogen 3.418 N/A LYS 204.A N LEU 201.A O no hydrogen 3.097 N/A LYS 206.A N CYS 203.A O no hydrogen 2.780 N/A LYS 206.A NZ ASP 173.A OD1 no hydrogen 2.775 N/A GLY 208.A N VAL 182.A O no hydrogen 2.730 N/A HIS 209.A ND1 THR 242.A OG1 no hydrogen 2.797 N/A HIS 209.A NE2 GLU 35.A OE1 no hydrogen 2.844 N/A HIS 211.A N LEU 184.A O no hydrogen 2.937 N/A HIS 211.A NE2 GLU 35.A OE1 no hydrogen 2.662 N/A LEU 212.A N VAL 244.A O no hydrogen 2.807 N/A GLY 213.A N THR 186.A OG1 no hydrogen 2.948 N/A GLU 214.A N LEU 218.A O no hydrogen 2.914 N/A GLN 215.A N GLN 215.A OE1 no hydrogen 2.832 N/A ARG 217.A N GLU 214.A O no hydrogen 2.852 N/A LEU 218.A N ASN 216.A OD1 no hydrogen 3.269 N/A GLY 221.A N GLU 214.A OE2 no hydrogen 2.819 N/A GLU 222.A N PRO 219.A O no hydrogen 3.051 N/A GLY 223.A N GLU 214.A OE2 no hydrogen 2.787 N/A ARG 224.A N GLN 215.A OE1 no hydrogen 2.989 N/A LEU 225.A N GLU 214.A OE1 no hydrogen 2.966 N/A TRP 227.A NE1 GLU 214.A OE2 no hydrogen 2.838 N/A ILE 230.A N PRO 226.A O no hydrogen 3.036 N/A PHE 231.A N TRP 227.A O no hydrogen 2.882 N/A GLY 232.A N ASP 228.A O no hydrogen 2.961 N/A ALA 233.A N GLU 229.A O no hydrogen 3.078 N/A LEU 234.A N ILE 230.A O no hydrogen 3.119 N/A LYS 235.A N PHE 231.A O no hydrogen 3.062 N/A LYS 235.A NZ LYS 288.A O no hydrogen 2.883 N/A LYS 235.A NZ ALA 290.A O no hydrogen 3.043 N/A LYS 235.A NZ GLU 292.A OE2 no hydrogen 3.412 N/A GLU 236.A N GLY 232.A O no hydrogen 2.992 N/A ILE 237.A N ALA 233.A O no hydrogen 3.088 N/A GLY 238.A N LYS 235.A O no hydrogen 2.881 N/A TYR 239.A N LEU 234.A O no hydrogen 2.967 N/A TYR 239.A OH THR 242.A O no hydrogen 2.613 N/A THR 242.A OG1 HIS 209.A ND1 no hydrogen 2.797 N/A ILE 243.A N LYS 3.A O no hydrogen 2.990 N/A VAL 244.A N PHE 210.A O no hydrogen 2.927 N/A MET 245.A N GLY 5.A O no hydrogen 2.913 N/A GLU 246.A N LEU 212.A O no hydrogen 2.892 N/A PHE 248.A N ARG 217.A O no hydrogen 2.996 N/A ARG 250.A NH1 TRP 11.A O no hydrogen 2.869 N/A ARG 250.A NH1 ASP 271.A OD1 no hydrogen 2.845 N/A ARG 250.A NH2 ALA 269.A O no hydrogen 3.006 N/A ARG 250.A NH2 ASP 271.A OD1 no hydrogen 2.835 N/A THR 251.A OG1 VAL 261.A O no hydrogen 2.864 N/A GLY 253.A N SER 256.A OG no hydrogen 3.312 N/A SER 254.A N GLU 14.A OE1 no hydrogen 3.458 N/A SER 254.A N GLU 14.A OE2 no hydrogen 3.333 N/A SER 254.A OG GLU 14.A OE1 no hydrogen 2.768 N/A VAL 255.A N THR 13.A O no hydrogen 2.839 N/A SER 256.A OG ARG 250.A O no hydrogen 2.971 N/A ARG 257.A N GLY 253.A O no hydrogen 3.028 N/A ALA 258.A N SER 254.A O no hydrogen 3.023 N/A VAL 259.A N VAL 255.A O no hydrogen 3.169 N/A CYS 260.A N ARG 257.A O no hydrogen 3.165 N/A VAL 261.A N SER 256.A O no hydrogen 2.836 N/A LEU 265.A N MET 249.A O no hydrogen 2.923 N/A SER 266.A N ASP 264.A OD1 no hydrogen 3.044 N/A SER 266.A OG ASP 264.A OD1 no hydrogen 2.506 N/A SER 266.A OG ASP 264.A OD2 no hydrogen 3.290 N/A GLY 268.A N ASP 264.A OD2 no hydrogen 2.724 N/A ALA 269.A N SER 266.A O no hydrogen 3.143 N/A ALA 269.A N SER 266.A OG no hydrogen 3.413 N/A THR 270.A N GLU 273.A OE1 no hydrogen 2.815 N/A GLU 273.A N THR 270.A OG1 no hydrogen 2.953 N/A MET 274.A N.A THR 270.A O no hydrogen 2.808 N/A MET 274.A N.B THR 270.A O no hydrogen 2.795 N/A ASP 275.A N ASP 271.A O no hydrogen 2.782 N/A GLU 276.A N GLU 272.A O no hydrogen 3.009 N/A ARG 277.A N GLU 273.A O no hydrogen 2.988 N/A ARG 277.A NE GLU 222.A OE2 no hydrogen 2.881 N/A ARG 277.A NH1 SER 266.A O no hydrogen 3.279 N/A ARG 277.A NH2 GLU 222.A OE1 no hydrogen 2.765 N/A ALA 278.A N MET 274.A O.A no hydrogen 2.962 N/A ALA 278.A N MET 274.A O.B no hydrogen 2.971 N/A ARG 279.A N ASP 275.A O no hydrogen 3.019 N/A ARG 279.A NH1 GLU 276.A OE1 no hydrogen 2.533 N/A ARG 280.A N GLU 276.A O no hydrogen 3.038 N/A SER 281.A N ARG 277.A O no hydrogen 2.992 N/A SER 281.A OG PRO 220.A O no hydrogen 2.741 N/A LEU 282.A N ALA 278.A O no hydrogen 2.926 N/A GLN 283.A N ARG 279.A O no hydrogen 3.081 N/A GLN 283.A NE2 GLN 283.A O no hydrogen 3.364 N/A GLN 283.A NE2 ASP 287.A OD1 no hydrogen 2.666 N/A PHE 284.A N ARG 280.A O no hydrogen 2.926 N/A VAL 285.A N SER 281.A O no hydrogen 3.001 N/A ARG 286.A N LEU 282.A O no hydrogen 2.889 N/A ARG 286.A NH1 ASP 32.A OD2 no hydrogen 3.292 N/A ARG 286.A NH2 GLY 30.A O no hydrogen 2.914 N/A ARG 286.A NH2 ASP 32.A OD1 no hydrogen 3.500 N/A ARG 286.A NH2 ASP 32.A OD2 no hydrogen 3.388 N/A ASP 287.A N GLN 283.A O no hydrogen 2.820 N/A LYS 288.A N PHE 284.A O no hydrogen 3.057 N/A LYS 288.A NZ ASP 228.A OD1 no hydrogen 2.943 N/A LEU 289.A N VAL 285.A O no hydrogen 2.921 N/A ALA 290.A N ASP 287.A O no hydrogen 3.327 N/A GLU 292.A N GLU 292.A OE1 no hydrogen 2.635 N/A HIS 295.A N GLU 292.A O no hydrogen 3.265 N/A HIS 296.A N HIS 293.A O no hydrogen 2.932 N/A HIS 297.A N HIS 294.A O no hydrogen 2.960 N/A