Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4q8l_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 2.A N ASP 25.A O no hydrogen 2.929 N/A SER 4.A OG SER 8.A OG no hydrogen 3.025 N/A ILE 6.A N PRO 3.A O no hydrogen 2.965 N/A THR 7.A N PRO 3.A O no hydrogen 3.010 N/A SER 8.A N SER 4.A O no hydrogen 2.855 N/A SER 8.A OG SER 4.A O no hydrogen 2.835 N/A SER 8.A OG SER 4.A OG no hydrogen 3.025 N/A GLY 9.A N ILE 6.A O no hydrogen 3.171 N/A SER 10.A OG SER 4.A O no hydrogen 3.483 N/A ILE 11.A N SER 5.A O no hydrogen 3.143 N/A PHE 12.A N SER 5.A O no hydrogen 3.164 N/A ASP 13.A N LYS 50.A O no hydrogen 2.779 N/A GLU 15.A N GLU 48.A O no hydrogen 2.719 N/A LEU 22.A N ASN 20.A OD1 no hydrogen 3.046 N/A VAL 23.A N THR 27.A O no hydrogen 3.239 N/A SER 26.A N ASP 24.A OD1 no hydrogen 2.742 N/A SER 26.A OG ASP 25.A OD2 no hydrogen 2.838 N/A THR 27.A N ASP 24.A O no hydrogen 3.521 N/A THR 27.A OG1 ASP 24.A OD1 no hydrogen 2.778 N/A THR 27.A OG1 ASP 24.A OD2 no hydrogen 3.245 N/A LEU 28.A N MET 217.A O no hydrogen 2.937 N/A VAL 29.A N PRO 21.A O no hydrogen 2.719 N/A PHE 30.A N VAL 215.A O no hydrogen 2.773 N/A VAL 31.A N HIS 47.A ND1 no hydrogen 2.847 N/A GLU 34.A N VAL 31.A O no hydrogen 2.953 N/A ALA 35.A N VAL 31.A O no hydrogen 2.858 N/A GLN 36.A N PRO 32.A O no hydrogen 2.744 N/A HIS 37.A NE2 GLU 15.A OE1 no hydrogen 2.781 N/A TRP 45.A N LEU 181.A O no hydrogen 3.133 N/A TRP 45.A NE1 SER 198.A OG no hydrogen 2.809 N/A ARG 46.A N HIS 37.A O no hydrogen 2.722 N/A ARG 46.A NH1 GLU 48.A OE1 no hydrogen 2.763 N/A ARG 46.A NH2 ILE 38.A O no hydrogen 3.032 N/A HIS 47.A N ASN 179.A O no hydrogen 2.957 N/A GLU 48.A N GLU 15.A O no hydrogen 3.095 N/A TYR 49.A N PHE 177.A O no hydrogen 2.857 N/A LYS 50.A N ASP 13.A O no hydrogen 2.981 N/A LYS 50.A NZ ASP 13.A OD1 no hydrogen 3.065 N/A LYS 50.A NZ GLU 15.A OE2 no hydrogen 2.827 N/A VAL 51.A N PHE 175.A O no hydrogen 2.987 N/A LYS 52.A N ILE 11.A O no hydrogen 2.986 N/A LYS 52.A NZ GLY 9.A O no hydrogen 2.854 N/A LYS 52.A NZ SER 10.A O no hydrogen 2.856 N/A LEU 55.A N LYS 52.A O no hydrogen 3.075 N/A ARG 56.A N GLU 53.A O no hydrogen 3.191 N/A ARG 56.A NE VAL 51.A O no hydrogen 3.076 N/A ARG 56.A NH2 VAL 51.A O no hydrogen 2.996 N/A ALA 58.A N GLN 61.A OE1 no hydrogen 2.955 N/A MET 59.A N ASP 170.A O no hydrogen 3.150 N/A THR 60.A N ASP 169.A OD1 no hydrogen 3.029 N/A THR 60.A OG1 ASP 169.A OD1 no hydrogen 3.406 N/A THR 60.A OG1 ASP 169.A OD2 no hydrogen 2.568 N/A GLN 61.A N ALA 58.A O no hydrogen 2.916 N/A THR 62.A N MET 59.A O no hydrogen 3.176 N/A THR 62.A OG1 GLU 64.A OE1 no hydrogen 3.361 N/A TYR 63.A N GLU 225.A O no hydrogen 2.821 N/A GLU 64.A N ASN 149.A O no hydrogen 2.994 N/A VAL 65.A N THR 223.A O no hydrogen 2.869 N/A PHE 66.A N VAL 147.A O no hydrogen 2.902 N/A GLU 67.A N SER 221.A O no hydrogen 2.941 N/A ALA 68.A N LEU 145.A O no hydrogen 3.045 N/A THR 69.A N THR 218.A O no hydrogen 2.814 N/A THR 69.A OG1 ASN 144.A OD1 no hydrogen 2.708 N/A THR 69.A OG1 ASN 219.A OD1 no hydrogen 3.102 N/A VAL 70.A N PHE 143.A O no hydrogen 2.747 N/A LYS 71.A N THR 216.A O no hydrogen 2.848 N/A VAL 72.A N GLU 141.A O no hydrogen 3.172 N/A GLU 73.A N LYS 214.A O no hydrogen 2.918 N/A MET 74.A N SER 139.A OG no hydrogen 2.943 N/A SER 75.A N GLU 212.A O no hydrogen 2.961 N/A SER 75.A OG GLY 209.A O no hydrogen 3.480 N/A SER 75.A OG GLU 212.A O no hydrogen 3.421 N/A GLY 77.A N ASP 100.A OD2 no hydrogen 2.839 N/A GLY 78.A N SER 75.A O no hydrogen 2.983 N/A THR 80.A N VAL 98.A O no hydrogen 3.026 N/A THR 80.A OG1 ILE 81.A O no hydrogen 3.526 N/A THR 80.A OG1 ASN 179.A OD1 no hydrogen 2.618 N/A ILE 81.A N TYR 180.A O no hydrogen 2.889 N/A ILE 82.A N VAL 96.A O no hydrogen 2.960 N/A GLN 84.A N LYS 176.A O no hydrogen 2.890 N/A HIS 85.A N SER 94.A O no hydrogen 2.927 N/A HIS 85.A N SER 94.A OG no hydrogen 3.032 N/A HIS 85.A ND1 SER 94.A OG no hydrogen 2.923 N/A HIS 85.A NE2 GLU 64.A OE1 no hydrogen 2.855 N/A HIS 86.A N TYR 174.A O no hydrogen 2.900 N/A ALA 87.A N GLY 91.A O no hydrogen 2.801 N/A SER 88.A N ASP 170.A OD1 no hydrogen 2.821 N/A SER 88.A OG ASP 170.A OD1 no hydrogen 3.161 N/A SER 88.A OG ASP 170.A OD2 no hydrogen 3.321 N/A THR 90.A N ALA 87.A O no hydrogen 2.799 N/A ILE 93.A N HIS 85.A O no hydrogen 2.873 N/A SER 94.A N HIS 85.A O no hydrogen 3.259 N/A SER 94.A OG HIS 85.A ND1 no hydrogen 2.923 N/A LYS 95.A N ARG 121.A O no hydrogen 2.866 N/A VAL 96.A N SER 83.A O no hydrogen 2.896 N/A TYR 97.A N TYR 119.A O no hydrogen 2.826 N/A VAL 98.A N THR 80.A O no hydrogen 2.982 N/A SER 99.A N ASP 117.A O no hydrogen 2.849 N/A ASP 100.A N GLY 78.A O no hydrogen 3.001 N/A ASP 102.A N PRO 186.A O no hydrogen 3.022 N/A GLU 103.A N THR 101.A OG1 no hydrogen 3.180 N/A PHE 106.A N SER 109.A OG no hydrogen 2.950 N/A ASP 108.A N ASP 117.A OD1 no hydrogen 2.866 N/A SER 109.A N ASP 117.A OD1 no hydrogen 3.390 N/A SER 109.A N ASP 117.A OD2 no hydrogen 2.958 N/A SER 109.A OG GLU 103.A O no hydrogen 2.772 N/A VAL 110.A N ASP 108.A OD2 no hydrogen 2.775 N/A ASN 112.A N ASP 100.A O no hydrogen 2.947 N/A ASN 112.A ND2 TYR 187.A OH no hydrogen 3.269 N/A ASN 113.A N ASP 100.A OD1 no hydrogen 3.096 N/A ASN 113.A ND2 ASP 108.A OD1 no hydrogen 3.126 N/A GLY 114.A N ASP 100.A OD2 no hydrogen 2.753 N/A ILE 115.A N ASN 113.A OD1 no hydrogen 2.976 N/A PHE 116.A N MET 137.A O no hydrogen 2.691 N/A ASP 117.A N SER 99.A O no hydrogen 2.706 N/A VAL 118.A N GLY 135.A O no hydrogen 2.835 N/A TYR 119.A N TYR 97.A O no hydrogen 3.177 N/A VAL 120.A N PHE 132.A O no hydrogen 2.960 N/A ARG 121.A N LYS 95.A O no hydrogen 2.787 N/A ARG 121.A NH1 GLU 129.A OE1 no hydrogen 3.121 N/A ARG 121.A NH2 GLU 103.A OE1 no hydrogen 2.711 N/A LEU 122.A N GLU 130.A O no hydrogen 2.907 N/A ARG 123.A N ILE 93.A O no hydrogen 2.856 N/A ARG 123.A NE THR 92.A O no hydrogen 2.682 N/A ARG 123.A NH1 THR 92.A O no hydrogen 3.569 N/A ARG 123.A NH2 GLY 127.A O no hydrogen 2.886 N/A ASN 124.A N ASN 128.A O no hydrogen 2.739 N/A GLY 127.A N ASN 124.A O no hydrogen 2.908 N/A GLU 130.A N LEU 122.A O no hydrogen 2.805 N/A LYS 131.A NZ GLU 103.A OE1 no hydrogen 2.813 N/A LYS 131.A NZ SER 104.A O no hydrogen 2.950 N/A PHE 132.A N VAL 120.A O no hydrogen 3.059 N/A LEU 134.A N VAL 118.A O no hydrogen 2.782 N/A GLY 135.A N VAL 118.A O no hydrogen 3.130 N/A MET 137.A N PHE 116.A O no hydrogen 2.959 N/A THR 138.A N GLU 141.A OE2 no hydrogen 3.052 N/A SER 139.A OG MET 74.A O no hydrogen 3.451 N/A GLY 140.A N VAL 72.A O no hydrogen 2.628 N/A GLU 141.A N THR 138.A O no hydrogen 3.088 N/A PHE 143.A N VAL 70.A O no hydrogen 2.807 N/A LEU 145.A N ALA 68.A O no hydrogen 2.800 N/A ARG 146.A N THR 157.A O no hydrogen 2.818 N/A ARG 146.A NH1 THR 157.A OG1 no hydrogen 3.327 N/A VAL 147.A N PHE 66.A O no hydrogen 2.839 N/A VAL 148.A N GLU 155.A O no hydrogen 2.758 N/A ASN 149.A N GLU 64.A O no hydrogen 2.861 N/A ASN 149.A ND2 MET 59.A O no hydrogen 3.504 N/A ASN 149.A ND2 GLU 64.A OE1 no hydrogen 3.219 N/A ASN 150.A N ASP 153.A O no hydrogen 2.789 N/A TYR 151.A N THR 62.A O no hydrogen 2.941 N/A GLY 152.A N ASN 149.A OD1 no hydrogen 2.846 N/A ASP 153.A N ASN 150.A O no hydrogen 2.988 N/A VAL 154.A N ILE 165.A O no hydrogen 2.990 N/A GLU 155.A N VAL 148.A O no hydrogen 2.788 N/A VAL 156.A N PHE 163.A O no hydrogen 2.856 N/A THR 157.A N ARG 146.A O no hydrogen 2.773 N/A THR 157.A OG1 SER 162.A OG no hydrogen 2.706 N/A ALA 158.A N ASN 161.A O no hydrogen 2.910 N/A ASN 161.A N ALA 158.A O no hydrogen 2.808 N/A SER 162.A OG THR 157.A OG1 no hydrogen 2.706 N/A PHE 163.A N VAL 156.A O no hydrogen 3.052 N/A ILE 165.A N VAL 154.A O no hydrogen 3.046 N/A VAL 167.A N GLY 152.A O no hydrogen 2.881 N/A GLU 168.A N ARG 123.A O no hydrogen 2.966 N/A ASP 170.A N ASP 169.A OD1 no hydrogen 2.862 N/A GLN 172.A N ASP 170.A OD1 no hydrogen 3.045 N/A SER 173.A N VAL 57.A O no hydrogen 2.908 N/A SER 173.A OG VAL 57.A O no hydrogen 2.822 N/A TYR 174.A N HIS 86.A O no hydrogen 2.949 N/A LYS 176.A N GLN 84.A O no hydrogen 2.810 N/A LYS 176.A NZ GLU 48.A OE1 no hydrogen 2.735 N/A PHE 177.A N TYR 49.A O no hydrogen 3.073 N/A GLY 178.A N ILE 82.A O no hydrogen 2.867 N/A ASN 179.A N HIS 47.A O no hydrogen 2.863 N/A ASN 179.A ND2 PHE 30.A O no hydrogen 3.187 N/A ASN 179.A ND2 SER 213.A OG no hydrogen 3.084 N/A TYR 180.A N ILE 81.A O no hydrogen 2.892 N/A LEU 181.A N TRP 45.A O no hydrogen 2.836 N/A GLN 182.A N LYS 79.A O no hydrogen 2.776 N/A SER 183.A N ASN 43.A O no hydrogen 2.846 N/A SER 183.A OG CYS 192.A O no hydrogen 2.964 N/A ASP 185.A N ASP 190.A O no hydrogen 2.893 N/A TYR 187.A N ASP 185.A OD1 no hydrogen 2.874 N/A THR 188.A N ASP 185.A OD1 no hydrogen 3.135 N/A LEU 189.A N ASP 185.A O no hydrogen 2.770 N/A ASP 190.A N THR 188.A OG1 no hydrogen 2.991 N/A CYS 192.A N SER 183.A O no hydrogen 2.836 N/A GLU 194.A N SER 200.A OG no hydrogen 2.877 N/A ASN 197.A N GLU 194.A O no hydrogen 3.007 N/A SER 198.A OG GLN 36.A O no hydrogen 3.550 N/A SER 200.A N ASN 197.A O no hydrogen 3.147 N/A SER 200.A OG GLU 194.A O no hydrogen 3.396 N/A SER 200.A OG ASN 197.A O no hydrogen 2.707 N/A PHE 201.A N SER 198.A O no hydrogen 3.031 N/A LYS 202.A N SER 198.A O no hydrogen 3.275 N/A ASN 203.A N ASN 199.A O no hydrogen 3.431 N/A CYS 204.A N SER 200.A O no hydrogen 3.166 N/A CYS 204.A SG SER 200.A O no hydrogen 3.183 N/A PHE 205.A N PHE 201.A O no hydrogen 2.991 N/A GLU 206.A N LYS 202.A O no hydrogen 3.111 N/A ASP 207.A N ASN 203.A O no hydrogen 2.997 N/A LEU 208.A N CYS 204.A O no hydrogen 2.915 N/A GLY 209.A N GLU 206.A O no hydrogen 3.110 N/A ILE 210.A N PHE 205.A O no hydrogen 2.824 N/A THR 211.A N SER 75.A OG no hydrogen 3.067 N/A GLU 212.A N SER 75.A OG no hydrogen 2.915 N/A LYS 214.A N GLU 73.A O no hydrogen 2.716 N/A VAL 215.A N PHE 30.A O no hydrogen 3.061 N/A THR 216.A N LYS 71.A O no hydrogen 2.919 N/A MET 217.A N LEU 28.A O no hydrogen 2.849 N/A THR 218.A N THR 69.A O no hydrogen 2.940 N/A SER 221.A N GLU 67.A O no hydrogen 2.865 N/A TYR 222.A OH GLU 64.A OE2 no hydrogen 2.584 N/A THR 223.A N VAL 65.A O no hydrogen 2.894 N/A ARG 224.A NH1 TYR 222.A OH no hydrogen 3.069 N/A ARG 224.A NH2 LEU 55.A O no hydrogen 2.984 N/A GLU 225.A N TYR 63.A O no hydrogen 2.786 N/A ASN 227.A N GLN 61.A O no hydrogen 3.032 N/A