Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4qqk_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 6.A N CYS 2.A O no hydrogen 3.110 N/A SER 7.A N TYR 3.A O no hydrogen 2.956 N/A SER 7.A OG TYR 3.A O no hydrogen 2.527 N/A VAL 8.A N SER 4.A O no hydrogen 2.985 N/A HIS 9.A N ASP 5.A O no hydrogen 3.353 N/A GLU 10.A N VAL 6.A O no hydrogen 2.816 N/A GLU 11.A N SER 7.A O no hydrogen 3.025 N/A MET 12.A N VAL 8.A O no hydrogen 3.181 N/A ILE 13.A N HIS 9.A O no hydrogen 3.073 N/A ALA 14.A N GLU 10.A O no hydrogen 2.834 N/A ASP 15.A N MET 12.A O no hydrogen 3.103 N/A ARG 18.A N ASP 15.A OD1 no hydrogen 2.997 N/A ARG 18.A NE MET 12.A O no hydrogen 3.014 N/A ARG 18.A NH1 GLU 107.A OE1 no hydrogen 2.684 N/A ARG 18.A NH2 MET 12.A O no hydrogen 3.434 N/A ARG 18.A NH2 THR 19.A OG1 no hydrogen 3.117 N/A THR 19.A N ASP 15.A O no hydrogen 2.913 N/A THR 19.A OG1 MET 12.A O no hydrogen 3.057 N/A THR 19.A OG1 ASP 15.A O no hydrogen 3.050 N/A ASP 20.A N ARG 16.A O no hydrogen 2.796 N/A ALA 21.A N VAL 17.A O no hydrogen 3.066 N/A TYR 22.A N ARG 18.A O no hydrogen 3.129 N/A TYR 22.A OH SER 106.A O no hydrogen 2.732 N/A ARG 23.A N THR 19.A O no hydrogen 2.886 N/A ARG 23.A NE GLN 54.A OE1 no hydrogen 3.030 N/A ARG 23.A NH2 GLN 54.A OE1 no hydrogen 3.075 N/A LEU 24.A N ASP 20.A O no hydrogen 2.860 N/A GLY 25.A N ALA 21.A O no hydrogen 2.716 N/A ILE 26.A N TYR 22.A O no hydrogen 2.941 N/A LEU 27.A N ARG 23.A O no hydrogen 2.829 N/A ARG 28.A N LEU 24.A O no hydrogen 2.941 N/A ARG 28.A NH1 LYS 253.A O no hydrogen 2.698 N/A ARG 28.A NH2 LYS 253.A O no hydrogen 3.057 N/A ASN 29.A N ILE 26.A O no hydrogen 2.958 N/A ASN 29.A ND2 GLY 25.A O no hydrogen 2.777 N/A ASN 29.A ND2 PRO 249.A O no hydrogen 2.856 N/A TRP 30.A N LEU 27.A O no hydrogen 2.983 N/A ALA 32.A N ASN 29.A O no hydrogen 2.982 N/A LEU 33.A N ASN 29.A O no hydrogen 3.025 N/A LEU 33.A N TRP 30.A O no hydrogen 3.133 N/A ARG 34.A N TRP 30.A O no hydrogen 2.815 N/A GLY 35.A N GLY 56.A O no hydrogen 2.862 N/A LYS 36.A N LEU 33.A O no hydrogen 2.811 N/A THR 37.A N ASP 102.A OD2 no hydrogen 2.894 N/A THR 37.A OG1 ASP 102.A OD2 no hydrogen 3.068 N/A VAL 38.A N ARG 59.A O no hydrogen 2.962 N/A LEU 39.A N ALA 103.A O no hydrogen 2.879 N/A ASP 40.A N TYR 61.A O no hydrogen 2.818 N/A VAL 41.A N VAL 105.A O no hydrogen 3.022 N/A GLY 42.A N VAL 63.A O no hydrogen 2.854 N/A ALA 43.A N VAL 63.A O no hydrogen 2.924 N/A GLY 44.A N GLU 64.A OE1 no hydrogen 2.718 N/A GLY 46.A N ALA 43.A O no hydrogen 2.832 N/A SER 49.A OG ASP 40.A OD2 no hydrogen 2.646 N/A ILE 50.A N GLY 46.A O no hydrogen 3.047 N/A PHE 51.A N ILE 47.A O no hydrogen 2.954 N/A CYS 52.A N LEU 48.A O no hydrogen 3.033 N/A CYS 52.A SG LEU 48.A O no hydrogen 3.363 N/A ALA 53.A N SER 49.A O no hydrogen 3.090 N/A GLN 54.A N ILE 50.A O no hydrogen 2.830 N/A ALA 55.A N PHE 51.A O no hydrogen 2.939 N/A GLY 56.A N ALA 53.A O no hydrogen 2.939 N/A ALA 57.A N CYS 52.A O no hydrogen 3.084 N/A ARG 58.A N LYS 36.A O no hydrogen 2.807 N/A ARG 59.A N LYS 36.A O no hydrogen 3.473 N/A VAL 60.A N ARG 84.A O no hydrogen 2.741 N/A TYR 61.A N VAL 38.A O no hydrogen 2.781 N/A TYR 61.A OH GLU 99.A OE2 no hydrogen 2.604 N/A ALA 62.A N HIS 86.A O no hydrogen 2.869 N/A VAL 63.A N ASP 40.A O no hydrogen 3.082 N/A GLU 64.A N LEU 88.A O no hydrogen 3.014 N/A SER 66.A N GLU 64.A OE2 no hydrogen 2.856 N/A SER 66.A OG GLU 64.A OE2 no hydrogen 2.822 N/A TRP 69.A N SER 66.A O no hydrogen 3.105 N/A GLN 70.A N ALA 67.A O no hydrogen 3.050 N/A GLN 71.A NE2 ALA 67.A O no hydrogen 3.496 N/A ALA 72.A N ILE 68.A O no hydrogen 2.995 N/A ARG 73.A N TRP 69.A O no hydrogen 2.882 N/A GLU 74.A N GLN 70.A O no hydrogen 3.145 N/A VAL 75.A N GLN 71.A O no hydrogen 2.846 N/A VAL 76.A N ALA 72.A O no hydrogen 2.887 N/A ARG 77.A N ARG 73.A O no hydrogen 2.983 N/A PHE 78.A N GLU 74.A O no hydrogen 2.721 N/A ASN 79.A N VAL 75.A O no hydrogen 3.035 N/A ASN 79.A ND2 VAL 75.A O no hydrogen 2.687 N/A GLY 80.A N ARG 77.A O no hydrogen 2.759 N/A LEU 81.A N VAL 76.A O no hydrogen 3.005 N/A GLU 82.A N GLU 82.A OE2 no hydrogen 3.066 N/A ARG 84.A N LEU 81.A O no hydrogen 2.926 N/A ARG 84.A NE ALA 57.A O no hydrogen 3.225 N/A ARG 84.A NH2 ALA 53.A O no hydrogen 2.773 N/A ARG 84.A NH2 ALA 57.A O no hydrogen 2.765 N/A VAL 85.A N LEU 81.A O no hydrogen 2.760 N/A HIS 86.A N VAL 60.A O no hydrogen 2.801 N/A LEU 88.A N ALA 62.A O no hydrogen 2.802 N/A GLY 90.A N GLU 64.A O no hydrogen 2.934 N/A GLU 93.A N GLU 93.A OE1 no hydrogen 2.794 N/A THR 94.A N PRO 91.A O no hydrogen 3.211 N/A THR 94.A OG1 PRO 91.A O no hydrogen 3.486 N/A VAL 95.A N PRO 91.A O no hydrogen 3.194 N/A VAL 95.A N VAL 92.A O no hydrogen 3.414 N/A GLN 100.A NE2.A LYS 128.A O no hydrogen 3.330 N/A GLN 100.A NE2.B LYS 128.A O no hydrogen 2.996 N/A VAL 101.A N TRP 129.A O no hydrogen 2.738 N/A ASP 102.A N THR 37.A O no hydrogen 2.947 N/A ASP 102.A N THR 37.A OG1 no hydrogen 3.126 N/A ALA 103.A N THR 37.A O no hydrogen 3.112 N/A ILE 104.A N LEU 135.A O no hydrogen 2.892 N/A VAL 105.A N LEU 39.A O no hydrogen 2.955 N/A SER 106.A N LEU 137.A O no hydrogen 3.108 N/A SER 106.A OG VAL 41.A O no hydrogen 2.927 N/A MET 109.A N GLU 107.A OE2 no hydrogen 3.265 N/A GLY 110.A N LEU 113.A O no hydrogen 2.913 N/A LEU 114.A N GLY 112.A O no hydrogen 2.730 N/A HIS 115.A N TYR 111.A O no hydrogen 3.071 N/A GLU 116.A N ARG 301.A O no hydrogen 2.876 N/A MET 118.A N TRP 108.A O no hydrogen 2.858 N/A LEU 119.A N SER 117.A OG no hydrogen 3.006 N/A SER 121.A OG GLU 93.A OE2 no hydrogen 2.594 N/A VAL 122.A N MET 118.A O no hydrogen 3.051 N/A LEU 123.A N LEU 119.A O no hydrogen 2.880 N/A HIS 124.A N SER 120.A O no hydrogen 2.963 N/A ALA 125.A N SER 121.A O no hydrogen 2.938 N/A ARG 126.A N VAL 122.A O no hydrogen 2.830 N/A ARG 126.A NH2.B LEU 210.A O no hydrogen 3.045 N/A THR 127.A N LEU 123.A O no hydrogen 3.081 N/A THR 127.A OG1 LEU 123.A O no hydrogen 3.257 N/A LYS 128.A N HIS 124.A O no hydrogen 2.957 N/A LYS 128.A NZ GLU 93.A O no hydrogen 3.226 N/A TRP 129.A N ALA 125.A O no hydrogen 2.773 N/A LEU 130.A N ARG 126.A O no hydrogen 3.151 N/A LYS 131.A N VAL 101.A O no hydrogen 2.921 N/A LYS 131.A NZ ASP 102.A OD1 no hydrogen 2.896 N/A GLY 134.A N LYS 131.A O no hydrogen 2.757 N/A LEU 135.A N ASP 102.A O no hydrogen 2.972 N/A LEU 137.A N ILE 104.A O no hydrogen 2.857 N/A ALA 139.A N THR 247.A O no hydrogen 2.843 N/A ALA 141.A N LEU 208.A O no hydrogen 2.961 N/A GLU 142.A N GLN 245.A O no hydrogen 2.885 N/A LEU 143.A N ALA 206.A O no hydrogen 2.939 N/A PHE 144.A N TRP 243.A O no hydrogen 2.902 N/A ILE 145.A N GLN 203.A O no hydrogen 2.909 N/A VAL 146.A N ALA 241.A O no hydrogen 3.078 N/A ILE 148.A N GLY 239.A O no hydrogen 2.910 N/A SER 149.A N ASP 197.A O no hydrogen 2.803 N/A SER 149.A OG PRO 236.A O no hydrogen 2.596 N/A ASP 150.A N HIS 238.A ND1 no hydrogen 2.964 N/A GLN 151.A NE2 ASP 197.A OD1 no hydrogen 2.767 N/A LEU 153.A N ASP 150.A OD1 no hydrogen 3.093 N/A GLU 154.A N ASP 150.A O no hydrogen 2.893 N/A TRP 155.A N GLN 151.A O no hydrogen 2.978 N/A ARG 156.A N MET 152.A O no hydrogen 3.056 N/A LEU 157.A N LEU 153.A O no hydrogen 2.815 N/A GLY 158.A N GLU 154.A O no hydrogen 3.065 N/A PHE 159.A N ARG 156.A O no hydrogen 3.416 N/A SER 161.A N GLY 158.A O no hydrogen 3.063 N/A SER 161.A OG GLU 175.A OE2 no hydrogen 2.834 N/A GLN 162.A N PHE 159.A O no hydrogen 2.982 N/A HIS 166.A N VAL 163.A O no hydrogen 2.806 N/A TYR 167.A N VAL 163.A O no hydrogen 2.840 N/A GLY 168.A N LYS 164.A O no hydrogen 2.999 N/A SER 172.A N ASP 170.A OD1 no hydrogen 3.084 N/A SER 172.A OG ASP 170.A OD1 no hydrogen 2.727 N/A CYS 173.A SG ASP 170.A O no hydrogen 4.038 N/A LEU 174.A N MET 171.A O no hydrogen 2.806 N/A GLU 175.A N SER 172.A O no hydrogen 3.203 N/A ALA 178.A N LEU 174.A O no hydrogen 2.887 N/A THR 179.A N GLU 175.A O no hydrogen 2.844 N/A THR 179.A OG1 GLU 175.A O no hydrogen 2.864 N/A ARG 180.A N GLY 176.A O no hydrogen 2.872 N/A CYS 181.A N PHE 177.A O no hydrogen 2.882 N/A CYS 181.A SG PHE 177.A O no hydrogen 3.140 N/A LEU 182.A N ALA 178.A O no hydrogen 2.859 N/A MET 183.A N THR 179.A O no hydrogen 2.893 N/A GLY 184.A N ARG 180.A O no hydrogen 2.926 N/A HIS 185.A NE2 LEU 182.A O no hydrogen 2.816 N/A SER 186.A OG ASP 320.A O no hydrogen 3.408 N/A GLU 187.A N HIS 185.A ND1 no hydrogen 3.038 N/A ILE 188.A N ALA 322.A O no hydrogen 2.986 N/A VAL 189.A N LEU 272.A O no hydrogen 3.078 N/A GLN 191.A N GLN 270.A O no hydrogen 2.959 N/A GLN 191.A NE2 ASP 150.A OD1 no hydrogen 2.974 N/A LEU 193.A N GLN 270.A OE1 no hydrogen 2.705 N/A SER 194.A N ASP 197.A OD2 no hydrogen 2.901 N/A SER 194.A OG GLU 196.A OE1 no hydrogen 3.158 N/A ASP 197.A N SER 194.A O no hydrogen 3.025 N/A VAL 198.A N GLY 195.A O no hydrogen 3.193 N/A LEU 199.A N PRO 147.A O no hydrogen 2.965 N/A GLN 203.A N ILE 145.A O no hydrogen 2.887 N/A GLN 203.A NE2 ARG 201.A O no hydrogen 2.889 N/A ARG 204.A NH1 GLU 142.A OE2 no hydrogen 2.915 N/A PHE 205.A N LEU 143.A O no hydrogen 2.766 N/A GLN 207.A NE2 GLU 209.A OE1 no hydrogen 3.112 N/A LEU 208.A N ALA 141.A O no hydrogen 2.745 N/A LEU 210.A N ALA 139.A O no hydrogen 3.094 N/A ARG 212.A N GLU 209.A O no hydrogen 2.882 N/A ARG 212.A NE GLU 218.A OE2 no hydrogen 2.817 N/A ARG 212.A NH1 GLN 207.A O no hydrogen 3.072 N/A ARG 212.A NH1 GLU 218.A OE1 no hydrogen 2.950 N/A ARG 212.A NH1 GLU 218.A OE2 no hydrogen 3.516 N/A ARG 212.A NH2 GLN 207.A O no hydrogen 3.476 N/A ARG 212.A NH2 GLN 207.A OE1 no hydrogen 3.276 N/A LEU 215.A N ARG 212.A O no hydrogen 3.391 N/A GLU 216.A N GLU 216.A OE1 no hydrogen 3.016 N/A GLU 218.A N GLY 214.A O no hydrogen 3.042 N/A LEU 219.A N LEU 215.A O no hydrogen 2.937 N/A GLU 220.A N GLU 216.A O no hydrogen 3.108 N/A ALA 221.A N GLN 217.A O no hydrogen 3.079 N/A GLY 222.A N GLU 218.A O no hydrogen 2.758 N/A VAL 223.A N LEU 293.A O no hydrogen 3.035 N/A GLY 225.A N ILE 291.A O no hydrogen 2.897 N/A PHE 227.A N GLY 289.A O no hydrogen 2.930 N/A ARG 228.A NH1 ASP 286.A OD2 no hydrogen 2.571 N/A CYS 229.A N VAL 287.A O no hydrogen 2.901 N/A CYS 229.A SG VAL 287.A O no hydrogen 3.707 N/A CYS 231.A N THR 285.A O no hydrogen 2.817 N/A CYS 231.A SG THR 285.A O no hydrogen 3.548 N/A TYR 232.A N LEU 199.A O no hydrogen 2.801 N/A SER 234.A OG GLU 282.A OE1 no hydrogen 2.273 N/A ALA 235.A N VAL 281.A O no hydrogen 3.169 N/A MET 237.A N VAL 279.A O no hydrogen 2.726 N/A HIS 238.A N ILE 148.A O no hydrogen 2.930 N/A PHE 240.A N LEU 273.A O no hydrogen 2.877 N/A ALA 241.A N VAL 146.A O no hydrogen 2.918 N/A ILE 242.A N ALA 271.A O no hydrogen 2.827 N/A TRP 243.A N PHE 144.A O no hydrogen 3.058 N/A PHE 244.A N THR 259.A OG1 no hydrogen 3.030 N/A GLN 245.A N GLU 142.A O no hydrogen 3.005 N/A GLN 245.A NE2 GLU 142.A OE1 no hydrogen 2.704 N/A VAL 246.A N LEU 257.A O no hydrogen 2.909 N/A THR 247.A N SER 140.A O no hydrogen 3.056 N/A PHE 248.A N LEU 255.A O no hydrogen 2.745 N/A LEU 255.A N PHE 248.A O no hydrogen 2.866 N/A LEU 257.A N VAL 246.A O no hydrogen 2.859 N/A SER 258.A OG HIS 263.A ND1 no hydrogen 2.717 N/A THR 259.A N PHE 244.A O no hydrogen 2.993 N/A THR 259.A OG1 PHE 244.A O no hydrogen 2.653 N/A SER 260.A N SER 258.A OG no hydrogen 3.179 N/A PHE 262.A N SER 260.A OG no hydrogen 3.037 N/A HIS 263.A N SER 260.A O no hydrogen 3.051 N/A HIS 263.A ND1 SER 258.A OG no hydrogen 2.717 N/A HIS 267.A N ASP 15.A OD2 no hydrogen 2.926 N/A HIS 267.A ND1 ASP 15.A OD2 no hydrogen 2.729 N/A TRP 268.A N THR 266.A OG1 no hydrogen 3.109 N/A TRP 268.A NE1 MET 109.A O no hydrogen 2.980 N/A LYS 269.A N THR 266.A O no hydrogen 3.140 N/A GLN 270.A N GLN 191.A O no hydrogen 3.193 N/A GLN 270.A NE2 THR 259.A O no hydrogen 2.876 N/A ALA 271.A N ILE 242.A O no hydrogen 3.021 N/A LEU 272.A N VAL 189.A O no hydrogen 2.687 N/A LEU 273.A N PHE 240.A O no hydrogen 2.746 N/A TYR 274.A OH ASP 150.A OD2 no hydrogen 2.609 N/A LEU 275.A N HIS 238.A O no hydrogen 2.867 N/A VAL 279.A N MET 237.A O no hydrogen 3.005 N/A VAL 281.A N ALA 235.A O no hydrogen 2.942 N/A GLU 282.A N THR 285.A OG1 no hydrogen 2.898 N/A ASP 284.A N CYS 231.A O no hydrogen 2.789 N/A THR 285.A N GLU 282.A O no hydrogen 3.034 N/A THR 285.A OG1 GLU 282.A O no hydrogen 2.993 N/A VAL 287.A N CYS 229.A O no hydrogen 2.928 N/A SER 288.A N LYS 310.A O no hydrogen 3.038 N/A GLY 289.A N PHE 227.A O no hydrogen 3.059 N/A GLU 290.A N ARG 308.A O no hydrogen 2.804 N/A ILE 291.A N GLY 225.A O no hydrogen 2.979 N/A THR 292.A N LEU 306.A O no hydrogen 2.880 N/A LEU 293.A N VAL 223.A O no hydrogen 2.791 N/A LEU 294.A N ARG 304.A O no hydrogen 2.905 N/A SER 296.A N ARG 302.A O no hydrogen 2.951 N/A SER 296.A OG ASN 299.A O no hydrogen 2.720 N/A ARG 297.A NE ASP 298.A OD1 no hydrogen 3.159 N/A ARG 297.A NH2 ASP 298.A OD1 no hydrogen 3.511 N/A ASN 299.A N SER 296.A OG no hydrogen 3.173 N/A ARG 301.A N ASN 299.A OD1 no hydrogen 3.137 N/A ARG 302.A N ASN 299.A O no hydrogen 2.996 N/A LEU 303.A N HIS 115.A ND1 no hydrogen 3.075 N/A ARG 304.A N LEU 294.A O no hydrogen 2.908 N/A ARG 304.A NE PRO 295.A O no hydrogen 3.336 N/A ARG 304.A NH2 PRO 295.A O no hydrogen 3.132 N/A VAL 305.A N PHE 321.A O no hydrogen 2.887 N/A LEU 306.A N THR 292.A O no hydrogen 2.836 N/A LEU 307.A N ASP 320.A OD1 no hydrogen 3.147 N/A ARG 308.A N GLU 290.A O no hydrogen 2.954 N/A ARG 308.A NE GLU 316.A OE1 no hydrogen 2.880 N/A ARG 308.A NH1 THR 318.A OG1 no hydrogen 2.871 N/A ARG 308.A NH2 GLU 316.A OE1 no hydrogen 3.326 N/A TYR 309.A N LYS 317.A O no hydrogen 2.891 N/A LYS 310.A N SER 288.A O no hydrogen 2.800 N/A LYS 310.A NZ GLY 312.A O no hydrogen 3.235 N/A LYS 310.A NZ GLN 314.A O no hydrogen 2.540 N/A GLY 312.A N ASP 286.A O no hydrogen 2.798 N/A GLN 314.A N VAL 311.A O no hydrogen 3.039 N/A GLU 315.A N GLU 315.A OE1 no hydrogen 2.655 N/A LYS 317.A N TYR 309.A O no hydrogen 2.855 N/A LYS 319.A N LEU 307.A O no hydrogen 2.942 N/A LYS 319.A NZ HIS 185.A O no hydrogen 2.905 N/A LYS 319.A NZ TYR 274.A O no hydrogen 2.783 N/A LYS 319.A NZ ASN 276.A OD1 no hydrogen 2.800 N/A PHE 321.A N VAL 305.A O no hydrogen 2.813 N/A ALA 322.A N SER 186.A O no hydrogen 2.942 N/A MET 323.A N LEU 303.A O no hydrogen 3.037 N/A