Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4r1c_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 1.A ND2 THR 258.A O no hydrogen 2.899 N/A TRP 3.A N ASN 1.A OD1 no hydrogen 2.957 N/A THR 4.A OG1 ASN 1.A O no hydrogen 3.131 N/A MET 7.A N TRP 3.A O no hydrogen 2.732 N/A ALA 8.A N GLU 5.A O no hydrogen 3.311 N/A LYS 9.A NZ LYS 173.A O no hydrogen 3.402 N/A TYR 10.A N MET 7.A O no hydrogen 2.923 N/A ASP 11.A N ALA 8.A O no hydrogen 3.069 N/A GLU 14.A N ASP 11.A O no hydrogen 2.939 N/A GLU 14.A N ASP 11.A OD2 no hydrogen 3.319 N/A VAL 15.A N ASP 11.A O no hydrogen 2.840 N/A HIS 16.A N ILE 12.A O no hydrogen 2.980 N/A HIS 16.A NE2 GLY 19.A O no hydrogen 2.955 N/A GLY 17.A N ILE 12.A O no hydrogen 3.114 N/A SER 18.A OG ASP 23.A OD1 no hydrogen 2.589 N/A SER 18.A OG SER 39.A OG no hydrogen 3.176 N/A SER 18.A OG ASP 221.A OD2 no hydrogen 3.144 N/A GLY 19.A N SER 18.A OG no hydrogen 2.752 N/A GLY 19.A N ASP 221.A OD2 no hydrogen 3.056 N/A ILE 20.A N ALA 219.A O no hydrogen 2.675 N/A ARG 21.A N ALA 219.A O no hydrogen 3.139 N/A ARG 21.A NE GLU 216.A OE1 no hydrogen 3.074 N/A ARG 21.A NH1 GLU 144.A OE1 no hydrogen 2.837 N/A ARG 21.A NH1 GLU 144.A OE2 no hydrogen 3.395 N/A ARG 21.A NH2 GLU 144.A OE2 no hydrogen 2.714 N/A ASP 23.A N GLN 143.A OE1 no hydrogen 2.776 N/A LEU 24.A N ASP 221.A OD2 no hydrogen 2.824 N/A GLU 26.A N LEU 37.A O no hydrogen 3.339 N/A ALA 28.A N TYR 35.A O no hydrogen 2.749 N/A VAL 30.A N THR 33.A O no hydrogen 2.752 N/A ALA 31.A N ASP 117.A OD2 no hydrogen 2.560 N/A THR 33.A N VAL 30.A O no hydrogen 3.258 N/A TYR 35.A N ALA 28.A O no hydrogen 2.682 N/A ARG 36.A NH1 ASP 221.A O no hydrogen 2.928 N/A ARG 36.A NH2 ASP 221.A O no hydrogen 2.911 N/A ARG 36.A NH2 TYR 231.A O no hydrogen 3.198 N/A LEU 37.A N GLU 26.A O no hydrogen 3.051 N/A SER 39.A N ASP 23.A OD1 no hydrogen 2.868 N/A SER 39.A N ASP 23.A OD2 no hydrogen 3.047 N/A SER 39.A OG SER 18.A OG no hydrogen 3.176 N/A GLY 40.A N ASP 23.A OD2 no hydrogen 2.701 N/A LYS 41.A N HIS 16.A O no hydrogen 2.901 N/A LYS 41.A NZ GLU 14.A O no hydrogen 2.984 N/A LYS 41.A NZ VAL 15.A O no hydrogen 3.506 N/A CYS 42.A N HIS 16.A ND1 no hydrogen 3.113 N/A CYS 42.A SG VAL 15.A O no hydrogen 3.671 N/A VAL 44.A N TYR 162.A O no hydrogen 3.056 N/A PHE 45.A N LEU 272.A O no hydrogen 3.138 N/A GLY 46.A N TYR 160.A O no hydrogen 2.818 N/A LYS 47.A NZ ILE 20.A O no hydrogen 3.039 N/A LYS 47.A NZ ARG 21.A O no hydrogen 2.999 N/A LYS 47.A NZ GLN 143.A OE1 no hydrogen 2.719 N/A GLY 48.A N ALA 152.A O no hydrogen 2.926 N/A ILE 50.A N ARG 150.A O no hydrogen 2.858 N/A GLU 52.A N CYS 148.A O no hydrogen 2.634 N/A THR 56.A N SER 54.A OG no hydrogen 3.335 N/A THR 56.A OG1 THR 60.A OG1 no hydrogen 3.231 N/A THR 60.A N THR 57.A O no hydrogen 3.031 N/A THR 60.A OG1 THR 56.A OG1 no hydrogen 3.231 N/A THR 60.A OG1 THR 57.A O no hydrogen 3.040 N/A VAL 62.A N ALA 70.A O no hydrogen 2.656 N/A GLY 68.A N PRO 61.A O no hydrogen 3.147 N/A PHE 69.A N PHE 58.A O no hydrogen 2.654 N/A ALA 70.A N THR 60.A O no hydrogen 3.292 N/A PHE 71.A N ILE 137.A O no hydrogen 2.811 N/A THR 74.A OG1 PRO 76.A O no hydrogen 3.340 N/A MET 78.A N THR 74.A OG1 no hydrogen 3.078 N/A MET 81.A N CYS 135.A O no hydrogen 2.949 N/A THR 82.A N GLU 85.A OE1 no hydrogen 2.973 N/A LEU 83.A N LYS 133.A O no hydrogen 2.978 N/A GLU 85.A N THR 82.A OG1 no hydrogen 3.090 N/A MET 86.A N THR 82.A O no hydrogen 2.869 N/A ARG 87.A N LEU 83.A O no hydrogen 3.031 N/A ARG 87.A NH1 LYS 97.A O no hydrogen 2.620 N/A ARG 87.A NH1 LEU 99.A O no hydrogen 2.998 N/A ARG 87.A NH2 LEU 99.A O no hydrogen 3.164 N/A HIS 88.A N ASP 84.A O no hydrogen 2.983 N/A PHE 89.A N GLU 85.A O no hydrogen 2.854 N/A TYR 90.A N MET 86.A O no hydrogen 3.091 N/A TYR 90.A OH HIS 108.A ND1 no hydrogen 2.540 N/A LYS 91.A N HIS 88.A O no hydrogen 3.026 N/A ASN 93.A N TYR 90.A O no hydrogen 3.096 N/A LYS 97.A N ASN 93.A O no hydrogen 3.095 N/A LYS 97.A NZ ASN 98.A OD1 no hydrogen 3.427 N/A LEU 99.A N VAL 96.A O no hydrogen 3.070 N/A LEU 102.A N ASP 100.A OD2 no hydrogen 3.048 N/A THR 103.A N ASP 100.A OD2 no hydrogen 3.219 N/A THR 103.A OG1 ASP 100.A OD1 no hydrogen 2.590 N/A THR 103.A OG1 ASP 100.A OD2 no hydrogen 3.518 N/A THR 103.A OG1 VAL 168.A O no hydrogen 3.404 N/A LEU 104.A N ASP 100.A O no hydrogen 2.935 N/A CYS 105.A N GLU 101.A O no hydrogen 3.029 N/A SER 106.A N LEU 102.A O no hydrogen 2.993 N/A SER 106.A OG SER 164.A O no hydrogen 2.769 N/A ARG 107.A N THR 103.A O no hydrogen 2.780 N/A ARG 107.A NH1 VAL 167.A O no hydrogen 2.933 N/A ARG 107.A NH2 VAL 167.A O no hydrogen 2.832 N/A HIS 108.A N LEU 104.A O no hydrogen 2.870 N/A HIS 108.A ND1 TYR 90.A OH no hydrogen 2.540 N/A HIS 108.A NE2 MET 78.A O no hydrogen 3.066 N/A ALA 109.A N CYS 105.A O no hydrogen 3.027 N/A GLY 110.A N SER 106.A O no hydrogen 2.946 N/A ASN 111.A N HIS 108.A O no hydrogen 3.133 N/A MET 112.A N ALA 109.A O no hydrogen 3.174 N/A ASP 117.A N PRO 114.A O no hydrogen 3.268 N/A ASN 119.A N ASP 117.A OD1 no hydrogen 3.195 N/A SER 120.A N ASP 117.A O no hydrogen 3.114 N/A SER 120.A OG GLU 29.A O no hydrogen 2.669 N/A TYR 122.A N SER 120.A OG no hydrogen 2.988 N/A ALA 126.A N LEU 163.A O no hydrogen 2.851 N/A VAL 127.A N HIS 136.A O no hydrogen 2.882 N/A TYR 128.A N THR 161.A O no hydrogen 3.051 N/A TYR 128.A OH GLU 101.A OE2 no hydrogen 3.161 N/A ASP 129.A N LYS 134.A O no hydrogen 2.856 N/A ASP 130.A N ASN 159.A O no hydrogen 2.842 N/A LYS 131.A N ASP 129.A OD1 no hydrogen 2.837 N/A LYS 134.A N ASP 129.A O no hydrogen 3.182 N/A CYS 135.A N MET 81.A O no hydrogen 2.787 N/A CYS 135.A SG CYS 105.A O no hydrogen 3.464 N/A HIS 136.A N VAL 127.A O no hydrogen 2.871 N/A ILE 137.A N SER 79.A OG no hydrogen 2.913 N/A LEU 138.A N PRO 125.A O no hydrogen 2.968 N/A ILE 140.A N PHE 69.A O no hydrogen 3.046 N/A GLN 143.A NE2 ASP 23.A O no hydrogen 3.029 N/A GLN 143.A NE2 ALA 141.A O no hydrogen 2.817 N/A ASN 145.A N PHE 149.A O no hydrogen 2.835 N/A ASN 145.A ND2 PHE 147.A O no hydrogen 3.099 N/A PHE 149.A N ASN 145.A O no hydrogen 2.962 N/A ARG 150.A N ILE 50.A O no hydrogen 2.969 N/A ARG 150.A NE GLU 52.A OE2 no hydrogen 2.641 N/A ALA 152.A N GLY 48.A O no hydrogen 2.965 N/A LYS 153.A NZ PHE 45.A O no hydrogen 2.883 N/A LYS 153.A NZ ASN 211.A OD1 no hydrogen 2.818 N/A LYS 153.A NZ ALA 271.A O no hydrogen 2.732 N/A SER 156.A N ASP 154.A OD1 no hydrogen 2.859 N/A SER 156.A OG ASP 154.A OD1 no hydrogen 2.494 N/A PHE 157.A N ASP 154.A O no hydrogen 2.672 N/A GLN 158.A N ILE 155.A O no hydrogen 3.360 N/A TYR 160.A N PHE 157.A O no hydrogen 2.760 N/A THR 161.A N TYR 128.A O no hydrogen 2.957 N/A TYR 162.A N VAL 44.A O no hydrogen 2.976 N/A LEU 163.A N ALA 126.A O no hydrogen 2.830 N/A SER 164.A OG GLY 40.A O no hydrogen 2.537 N/A LYS 165.A NZ GLU 26.A OE2 no hydrogen 2.895 N/A LYS 165.A NZ ASN 166.A OD1 no hydrogen 2.927 N/A ASN 166.A N SER 164.A OG no hydrogen 2.839 N/A ASN 166.A ND2 GLU 26.A OE1 no hydrogen 2.929 N/A ASN 166.A ND2 SER 39.A O no hydrogen 2.774 N/A VAL 167.A N SER 164.A O no hydrogen 3.523 N/A VAL 168.A N LYS 41.A O no hydrogen 2.984 N/A TRP 171.A NE1 ASP 100.A OD2 no hydrogen 2.725 N/A LYS 173.A N ASN 170.A O no hydrogen 2.946 N/A VAL 174.A N ASN 170.A O no hydrogen 3.273 N/A CYS 175.A N TRP 171.A O no hydrogen 2.888 N/A ARG 177.A NE GLU 277.A OE2 no hydrogen 2.736 N/A ARG 177.A NH2 GLU 277.A OE1 no hydrogen 2.869 N/A ARG 177.A NH2 GLU 277.A OE2 no hydrogen 3.511 N/A ASN 179.A N GLU 277.A O no hydrogen 2.908 N/A ASN 179.A ND2 HIS 274.A O no hydrogen 2.831 N/A ASN 179.A ND2 GLU 277.A O no hydrogen 2.890 N/A LEU 180.A N ALA 268.A O no hydrogen 3.083 N/A GLN 181.A N GLU 279.A O no hydrogen 2.958 N/A ALA 183.A N TYR 266.A O no hydrogen 3.168 N/A LYS 184.A N ILE 261.A O no hydrogen 2.878 N/A LYS 184.A NZ ASP 195.A OD1 no hydrogen 2.664 N/A PHE 185.A N ASN 242.A OD1 no hydrogen 2.741 N/A GLY 186.A N CYS 259.A O no hydrogen 2.839 N/A LEU 187.A N GLU 194.A O no hydrogen 2.866 N/A TRP 188.A N THR 258.A OG1 no hydrogen 2.786 N/A VAL 189.A N ASN 192.A O no hydrogen 2.957 N/A ASN 192.A N VAL 189.A O no hydrogen 3.264 N/A GLU 194.A N LEU 187.A O no hydrogen 2.909 N/A ASN 200.A N ILE 252.A O no hydrogen 2.775 N/A PHE 202.A N CYS 250.A O no hydrogen 2.983 N/A ALA 204.A N GLN 248.A O no hydrogen 3.017 N/A GLU 209.A N ASP 206.A OD1 no hydrogen 2.938 N/A CYS 210.A N ASP 206.A O no hydrogen 3.165 N/A ASN 211.A N LEU 207.A O no hydrogen 2.781 N/A ASN 211.A ND2 THR 269.A OG1 no hydrogen 2.877 N/A ASN 211.A ND2 THR 270.A O no hydrogen 2.895 N/A ASN 211.A ND2 SER 273.A O no hydrogen 3.668 N/A LYS 212.A N PHE 208.A O no hydrogen 2.937 N/A LYS 212.A NZ GLU 209.A OE1 no hydrogen 3.499 N/A LYS 212.A NZ GLU 209.A OE2 no hydrogen 3.522 N/A LEU 213.A N GLU 209.A O no hydrogen 3.092 N/A VAL 214.A N CYS 210.A O no hydrogen 3.000 N/A PHE 215.A N ASN 211.A O no hydrogen 2.896 N/A GLU 216.A N LYS 212.A O no hydrogen 2.951 N/A LEU 217.A N LEU 213.A O no hydrogen 3.178 N/A LEU 217.A N VAL 214.A O no hydrogen 3.128 N/A SER 218.A N PHE 215.A O no hydrogen 3.117 N/A SER 218.A OG PHE 215.A O no hydrogen 2.742 N/A ALA 219.A N ASN 239.A OD1 no hydrogen 2.748 N/A SER 220.A OG GLN 222.A O no hydrogen 3.191 N/A ASP 221.A N VAL 22.A O no hydrogen 2.911 N/A GLN 222.A NE2 GLU 144.A O no hydrogen 2.862 N/A LYS 224.A NZ GLU 216.A OE1 no hydrogen 2.896 N/A ARG 230.A NH1 TYR 231.A OH no hydrogen 3.182 N/A TYR 231.A N ALA 228.A O no hydrogen 3.231 N/A LYS 232.A N ASP 229.A O no hydrogen 2.847 N/A LYS 232.A NZ ASP 27.A OD2 no hydrogen 2.824 N/A SER 233.A N ASP 221.A OD1 no hydrogen 2.786 N/A SER 233.A OG ASP 221.A OD1 no hydrogen 2.904 N/A HIS 234.A NE2 ASP 229.A OD1 no hydrogen 2.861 N/A GLY 235.A N SER 233.A OG no hydrogen 3.022 N/A LYS 236.A N SER 233.A O no hydrogen 3.085 N/A LYS 236.A NZ SER 233.A O no hydrogen 3.167 N/A TYR 238.A N LEU 217.A O no hydrogen 3.238 N/A ASN 239.A ND2 GLY 235.A O no hydrogen 2.740 N/A TRP 240.A NE1 TYR 10.A O no hydrogen 2.785 N/A GLY 241.A N THR 269.A O no hydrogen 2.987 N/A ASN 242.A N GLU 251.A O no hydrogen 2.743 N/A ASN 242.A ND2 PHE 185.A O no hydrogen 3.334 N/A TYR 243.A N ILE 267.A O no hydrogen 2.739 N/A TYR 243.A OH ALA 204.A O no hydrogen 2.540 N/A ASN 244.A N LYS 249.A O no hydrogen 2.922 N/A ASN 244.A ND2 TYR 266.A OH no hydrogen 3.127 N/A THR 245.A N SER 265.A O no hydrogen 2.831 N/A THR 245.A OG1 SER 265.A O no hydrogen 2.999 N/A THR 247.A N ASN 244.A OD1 no hydrogen 3.023 N/A GLN 248.A NE2 ILE 205.A O no hydrogen 3.119 N/A LYS 249.A N ASN 244.A O no hydrogen 3.314 N/A CYS 250.A N PHE 202.A O no hydrogen 2.688 N/A CYS 250.A SG CYS 210.A O no hydrogen 3.495 N/A GLU 251.A N ASN 242.A O no hydrogen 2.893 N/A ILE 252.A N ASN 200.A O no hydrogen 2.719 N/A PHE 253.A N TRP 240.A O no hydrogen 3.152 N/A LYS 256.A NZ ASP 11.A OD1 no hydrogen 3.261 N/A THR 258.A N GLY 186.A O no hydrogen 2.947 N/A CYS 259.A N GLY 186.A O no hydrogen 3.257 N/A ILE 261.A N LYS 184.A O no hydrogen 2.781 N/A ASN 263.A N ASN 182.A O no hydrogen 2.995 N/A SER 265.A N ASN 263.A OD1 no hydrogen 2.912 N/A SER 265.A OG ASN 263.A OD1 no hydrogen 3.405 N/A TYR 266.A N ASN 263.A O no hydrogen 2.990 N/A TYR 266.A OH GLU 251.A OE1 no hydrogen 2.550 N/A ILE 267.A N TYR 243.A O no hydrogen 2.794 N/A ALA 268.A N LEU 180.A O no hydrogen 3.081 N/A THR 269.A N GLY 241.A O no hydrogen 2.991 N/A THR 269.A OG1 ASN 179.A OD1 no hydrogen 2.498 N/A THR 270.A N SER 273.A OG no hydrogen 3.111 N/A THR 270.A OG1 SER 273.A OG no hydrogen 2.687 N/A ALA 271.A N ASN 239.A O no hydrogen 2.933 N/A LEU 272.A N THR 270.A OG1 no hydrogen 3.134 N/A SER 273.A N THR 270.A O no hydrogen 2.976 N/A SER 273.A N THR 270.A OG1 no hydrogen 3.241 N/A SER 273.A OG THR 270.A O no hydrogen 3.229 N/A SER 273.A OG THR 270.A OG1 no hydrogen 2.687 N/A HIS 274.A N ARG 177.A O no hydrogen 2.747 N/A ILE 276.A N HIS 274.A ND1 no hydrogen 2.993 N/A GLU 277.A N HIS 274.A ND1 no hydrogen 3.049 N/A GLU 279.A N ASN 179.A O no hydrogen 2.801 N/A