Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4r28_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 6.A N ALA 2.A O no hydrogen 3.364 N/A ALA 7.A N TRP 3.A O no hydrogen 2.914 N/A GLU 8.A N ALA 4.A O no hydrogen 2.902 N/A VAL 9.A N ALA 5.A O no hydrogen 2.900 N/A ALA 10.A N SER 6.A O no hydrogen 2.905 N/A ASN 11.A N ALA 7.A O no hydrogen 2.915 N/A LYS 12.A N GLU 8.A O no hydrogen 3.272 N/A ARG 14.A NH1 PHE 214.A O no hydrogen 2.863 N/A ARG 14.A NH2 TRP 43.A O no hydrogen 3.529 N/A ARG 14.A NH2 LEU 44.A O no hydrogen 2.327 N/A VAL 16.A N VAL 212.A O no hydrogen 2.898 N/A VAL 18.A N ASP 210.A O no hydrogen 3.125 N/A GLY 19.A N PHE 171.A O no hydrogen 3.384 N/A ASP 20.A N PHE 17.A O no hydrogen 3.359 N/A LEU 22.A N VAL 169.A O no hydrogen 2.886 N/A ARG 23.A N VAL 39.A O no hydrogen 3.430 N/A ARG 23.A NH1 GLY 167.A O no hydrogen 3.146 N/A TYR 24.A N GLY 167.A O no hydrogen 3.412 N/A ALA 28.A N ALA 25.A O no hydrogen 3.444 N/A LEU 35.A N PHE 38.A O no hydrogen 2.558 N/A PHE 38.A N LEU 35.A O no hydrogen 3.024 N/A ASN 40.A N VAL 33.A O no hydrogen 2.928 N/A TYR 41.A N ARG 23.A O no hydrogen 3.351 N/A TRP 43.A N ASN 40.A OD1 no hydrogen 2.624 N/A LEU 44.A N ASN 40.A O no hydrogen 3.364 N/A THR 45.A N TYR 41.A O no hydrogen 2.901 N/A THR 45.A OG1 TYR 41.A O no hydrogen 2.594 N/A SER 46.A N HIS 42.A O no hydrogen 2.874 N/A LEU 50.A N PRO 47.A O no hydrogen 3.233 N/A LYS 54.A NZ GLN 26.A O no hydrogen 2.689 N/A LYS 54.A NZ ALA 28.A O no hydrogen 3.441 N/A GLU 58.A N ASN 62.A OD1 no hydrogen 2.798 N/A GLY 60.A N ARG 81.A O no hydrogen 2.914 N/A ASN 62.A N ALA 79.A O no hydrogen 2.891 N/A ASN 62.A ND2 GLU 58.A O no hydrogen 2.261 N/A VAL 67.A N ARG 74.A O no hydrogen 2.965 N/A SER 73.A OG VAL 67.A O no hydrogen 3.315 N/A ARG 74.A N VAL 67.A O no hydrogen 2.455 N/A ILE 78.A N PRO 148.A O no hydrogen 2.931 N/A ALA 79.A N ASN 62.A O no hydrogen 2.914 N/A ILE 80.A N PHE 150.A O no hydrogen 2.932 N/A ARG 81.A N GLY 60.A O no hydrogen 2.897 N/A SER 82.A N PHE 152.A O no hydrogen 2.915 N/A HIS 89.A N LYS 86.A O no hydrogen 3.024 N/A THR 91.A OG1 HIS 89.A O no hydrogen 3.568 N/A HIS 95.A N ASN 92.A O no hydrogen 3.404 N/A HIS 95.A ND1 ASN 92.A O no hydrogen 2.341 N/A GLU 97.A N ARG 106.A O no hydrogen 2.928 N/A ASP 99.A N HIS 104.A O no hydrogen 2.922 N/A HIS 104.A N ASP 99.A O no hydrogen 2.880 N/A VAL 105.A N LEU 201.A O no hydrogen 2.898 N/A ARG 106.A N GLU 97.A O no hydrogen 2.879 N/A ARG 106.A NE HIS 104.A NE2 no hydrogen 3.054 N/A ARG 106.A NH2 GLU 307.A O no hydrogen 3.425 N/A TYR 107.A N LEU 199.A O no hydrogen 2.907 N/A PHE 108.A N ASP 96.A OD2 no hydrogen 3.391 N/A GLY 109.A N LEU 197.A O no hydrogen 3.178 N/A ASP 110.A N ASN 125.A OD1 no hydrogen 3.093 N/A ARG 126.A N THR 122.A O no hydrogen 3.314 N/A LEU 127.A N LYS 123.A O no hydrogen 2.936 N/A LEU 128.A N GLY 124.A O no hydrogen 2.903 N/A LEU 129.A N ASN 125.A O no hydrogen 2.897 N/A LEU 129.A N ARG 126.A O no hydrogen 2.870 N/A GLU 130.A N ARG 126.A O no hydrogen 2.940 N/A ALA 131.A N LEU 127.A O no hydrogen 2.910 N/A ALA 132.A N LEU 128.A O no hydrogen 2.890 N/A ARG 133.A N LEU 129.A O no hydrogen 2.904 N/A ARG 133.A NH1 ARG 133.A O no hydrogen 3.031 N/A LEU 134.A N GLU 130.A O no hydrogen 2.943 N/A HIS 135.A N ALA 131.A O no hydrogen 2.864 N/A HIS 135.A NE2 PRO 147.A O no hydrogen 3.041 N/A ALA 136.A N ALA 132.A O no hydrogen 2.915 N/A THR 139.A OG1 THR 138.A O no hydrogen 2.284 N/A ARG 143.A NE VAL 242.A O no hydrogen 2.595 N/A LEU 144.A N ARG 140.A O no hydrogen 2.943 N/A ALA 146.A N ARG 143.A O no hydrogen 3.348 N/A PHE 150.A N ILE 78.A O no hydrogen 2.897 N/A LEU 151.A N GLY 173.A O no hydrogen 3.306 N/A PHE 152.A N ILE 80.A O no hydrogen 2.847 N/A ARG 153.A N GLU 170.A O no hydrogen 2.946 N/A ALA 154.A N SER 82.A O no hydrogen 3.415 N/A ARG 159.A N ARG 162.A O no hydrogen 2.556 N/A ARG 162.A N ARG 159.A O no hydrogen 3.106 N/A HIS 168.A ND1 GLY 167.A O no hydrogen 2.886 N/A VAL 169.A N LEU 22.A O no hydrogen 2.915 N/A GLU 170.A N ARG 153.A O no hydrogen 2.872 N/A CYS 172.A N LEU 151.A O no hydrogen 2.901 N/A CYS 172.A SG GLU 170.A OE2 no hydrogen 3.440 N/A ALA 175.A N LEU 149.A O no hydrogen 2.876 N/A ILE 176.A N ALA 202.A O no hydrogen 2.969 N/A ILE 177.A N HIS 135.A ND1 no hydrogen 3.217 N/A GLU 178.A N ASP 200.A O no hydrogen 2.974 N/A ARG 179.A N ASP 200.A O no hydrogen 2.939 N/A ARG 179.A NE GLU 181.A OE2 no hydrogen 2.588 N/A ARG 179.A NH2 GLU 181.A OE2 no hydrogen 2.870 N/A GLU 181.A N SER 198.A O no hydrogen 2.889 N/A VAL 183.A N ASN 196.A O no hydrogen 2.903 N/A GLN 185.A N PHE 194.A O no hydrogen 2.902 N/A SER 193.A OG ARG 192.A O no hydrogen 2.623 N/A PHE 194.A N GLN 185.A O no hydrogen 2.914 N/A ASN 196.A N VAL 183.A O no hydrogen 2.893 N/A ASN 196.A ND2 GLY 109.A O no hydrogen 3.495 N/A ASN 196.A ND2 GLN 185.A OE1 no hydrogen 2.711 N/A LEU 197.A N ASN 196.A OD1 no hydrogen 2.713 N/A SER 198.A N GLU 181.A O no hydrogen 2.902 N/A LEU 199.A N TYR 107.A O no hydrogen 2.889 N/A ASP 200.A N ARG 179.A O no hydrogen 2.912 N/A LEU 201.A N VAL 105.A O no hydrogen 2.942 N/A ALA 202.A N ILE 176.A O no hydrogen 3.158 N/A VAL 203.A N GLY 103.A O no hydrogen 3.092 N/A VAL 204.A N ALA 174.A O no hydrogen 3.031 N/A VAL 212.A N VAL 16.A O no hydrogen 2.914 N/A PHE 214.A N ARG 14.A O no hydrogen 2.676 N/A ARG 215.A N ASP 213.A OD1 no hydrogen 2.946 N/A ARG 215.A NH1 ALA 10.A O no hydrogen 2.488 N/A ASP 218.A N PHE 214.A O no hydrogen 3.072 N/A ASP 219.A N ARG 215.A O no hydrogen 2.920 N/A ARG 220.A N TRP 216.A O no hydrogen 2.884 N/A ARG 220.A NE ALA 76.A O no hydrogen 3.109 N/A ARG 220.A NH1 LEU 144.A O no hydrogen 2.849 N/A ARG 220.A NH2 LEU 144.A O no hydrogen 3.372 N/A ARG 221.A N ILE 217.A O no hydrogen 2.780 N/A THR 230.A OG1 ASP 219.A O no hydrogen 3.547 N/A SER 237.A OG SER 205.A O no hydrogen 2.408 N/A TRP 238.A N PRO 235.A O no hydrogen 3.268 N/A ARG 240.A N GLU 236.A O no hydrogen 2.902 N/A TRP 241.A N SER 237.A O no hydrogen 2.910 N/A VAL 242.A N TRP 238.A O no hydrogen 2.883 N/A ARG 243.A N ILE 239.A O no hydrogen 2.921 N/A GLN 244.A N ARG 240.A O no hydrogen 2.899 N/A GLY 245.A N TRP 241.A O no hydrogen 2.665 N/A ARG 246.A NH1 GLU 178.A O no hydrogen 3.390 N/A ARG 246.A NH2 GLU 178.A O no hydrogen 2.995 N/A ALA 248.A N GLY 245.A O no hydrogen 3.404 N/A ILE 249.A N ARG 246.A O no hydrogen 3.077 N/A GLY 251.A N ALA 248.A O no hydrogen 3.079 N/A ILE 252.A N ALA 248.A O no hydrogen 2.987 N/A ARG 253.A NH1 GLU 178.A OE1 no hydrogen 2.523 N/A ARG 254.A N VAL 203.A O no hydrogen 2.950 N/A ARG 254.A NE ASP 210.A OD1 no hydrogen 3.472 N/A ARG 254.A NH2 ASP 210.A OD2 no hydrogen 3.246 N/A ARG 255.A NH1 ASP 101.A O no hydrogen 2.919 N/A VAL 256.A N ASP 101.A O no hydrogen 3.049 N/A VAL 261.A N SER 259.A OG no hydrogen 3.406 N/A GLN 262.A N GLN 389.A OE1 no hydrogen 2.473 N/A SER 263.A N GLU 266.A OE1 no hydrogen 3.243 N/A GLU 266.A N SER 263.A OG no hydrogen 3.354 N/A GLN 267.A N SER 263.A O no hydrogen 3.220 N/A GLN 268.A N SER 264.A O no hydrogen 3.131 N/A GLN 268.A NE2 THR 381.A O no hydrogen 2.782 N/A GLN 268.A NE2 SER 383.A OG no hydrogen 3.109 N/A SER 273.A N ALA 270.A O no hydrogen 3.299 N/A ALA 276.A N SER 273.A O no hydrogen 3.369 N/A THR 278.A OG1 GLU 275.A O no hydrogen 2.324 N/A LEU 279.A N GLU 275.A O no hydrogen 2.902 N/A GLN 280.A N ALA 276.A O no hydrogen 2.912 N/A THR 281.A N ALA 277.A O no hydrogen 2.917 N/A THR 281.A OG1 ALA 277.A O no hydrogen 3.391 N/A THR 281.A OG1 THR 278.A O no hydrogen 2.421 N/A LEU 282.A N THR 278.A O no hydrogen 2.897 N/A TYR 283.A N LEU 279.A O no hydrogen 2.905 N/A TYR 283.A OH GLN 353.A OE1 no hydrogen 2.959 N/A LYS 284.A N GLN 280.A O no hydrogen 2.923 N/A PHE 285.A N THR 281.A O no hydrogen 2.896 N/A TYR 286.A N LEU 282.A O no hydrogen 2.963 N/A TYR 286.A OH THR 430.A OG1 no hydrogen 2.578 N/A ARG 289.A NH1 HIS 291.A ND1 no hydrogen 2.956 N/A ARG 289.A NH2 SER 320.A O no hydrogen 2.590 N/A GLU 294.A N LYS 290.A O no hydrogen 2.911 N/A LEU 295.A N HIS 291.A O no hydrogen 2.926 N/A LEU 296.A N ALA 292.A O no hydrogen 2.930 N/A ALA 297.A N PHE 293.A O no hydrogen 2.895 N/A SER 298.A N GLU 294.A O no hydrogen 2.900 N/A SER 298.A OG LEU 295.A O no hydrogen 2.297 N/A ARG 299.A N LEU 295.A O no hydrogen 2.961 N/A VAL 300.A N LEU 296.A O no hydrogen 2.898 N/A ALA 301.A N ALA 297.A O no hydrogen 2.898 N/A ALA 302.A N SER 298.A O no hydrogen 2.922 N/A GLU 303.A N ARG 299.A O no hydrogen 2.924 N/A VAL 304.A N VAL 300.A O no hydrogen 2.888 N/A PHE 305.A N ALA 301.A O no hydrogen 2.924 N/A ARG 306.A N ALA 302.A O no hydrogen 2.907 N/A GLU 307.A N VAL 304.A O no hydrogen 3.290 N/A GLY 309.A N ARG 306.A O no hydrogen 3.003 N/A LYS 313.A N ARG 331.A O no hydrogen 3.463 N/A LEU 317.A N ALA 437.A O no hydrogen 2.996 N/A SER 318.A OG VAL 326.A O no hydrogen 2.501 N/A ARG 319.A NH1 VAL 326.A O no hydrogen 2.667 N/A SER 321.A OG ARG 319.A O no hydrogen 2.950 N/A ASP 327.A N GLN 348.A OE1 no hydrogen 3.022 N/A PHE 328.A N GLY 347.A O no hydrogen 2.891 N/A ILE 329.A N TRP 316.A O no hydrogen 3.218 N/A GLY 330.A N VAL 345.A O no hydrogen 2.888 N/A ILE 332.A N VAL 343.A O no hydrogen 2.919 N/A ASP 333.A N ARG 311.A O no hydrogen 3.367 N/A MET 334.A N THR 341.A O no hydrogen 2.901 N/A LEU 337.A N SER 336.A OG no hydrogen 2.400 N/A SER 340.A OG SER 336.A O no hydrogen 2.435 N/A SER 340.A OG ALA 339.A O no hydrogen 2.888 N/A THR 341.A N MET 334.A O no hydrogen 2.914 N/A VAL 343.A N ILE 332.A O no hydrogen 2.897 N/A VAL 345.A N GLY 330.A O no hydrogen 2.900 N/A LEU 346.A N ILE 375.A O no hydrogen 2.987 N/A GLY 347.A N PHE 328.A O no hydrogen 2.870 N/A GLN 348.A N VAL 377.A O no hydrogen 3.029 N/A ALA 349.A N ASP 327.A OD2 no hydrogen 2.250 N/A CYS 351.A SG TYR 283.A O no hydrogen 4.040 N/A CYS 351.A SG TYR 286.A O no hydrogen 3.975 N/A GLN 353.A N GLN 353.A OE1 no hydrogen 2.574 N/A SER 356.A N GLN 353.A O no hydrogen 2.876 N/A GLU 361.A N GLU 361.A OE1 no hydrogen 2.637 N/A GLN 362.A N SER 359.A O no hydrogen 3.209 N/A ALA 364.A N PRO 360.A O no hydrogen 2.917 N/A ARG 365.A N GLU 361.A O no hydrogen 2.916 N/A VAL 366.A N VAL 363.A O no hydrogen 2.993 N/A VAL 367.A N VAL 363.A O no hydrogen 2.930 N/A ALA 368.A N ALA 364.A O no hydrogen 2.905 N/A ARG 369.A N VAL 366.A O no hydrogen 3.471 N/A LEU 370.A N VAL 367.A O no hydrogen 2.949 N/A TRP 374.A N ARG 371.A O no hydrogen 3.209 N/A ILE 375.A N VAL 344.A O no hydrogen 3.315 N/A GLY 376.A N PRO 398.A O no hydrogen 3.098 N/A VAL 377.A N LEU 346.A O no hydrogen 3.275 N/A TYR 378.A N VAL 400.A O no hydrogen 2.900 N/A VAL 379.A N GLN 348.A O no hydrogen 3.175 N/A THR 380.A N ILE 402.A O no hydrogen 2.916 N/A THR 380.A OG1 LYS 350.A O no hydrogen 3.340 N/A SER 383.A OG SER 264.A O no hydrogen 2.995 N/A PHE 384.A N GLN 267.A OE1 no hydrogen 2.621 N/A SER 385.A N VAL 358.A O no hydrogen 3.251 N/A SER 385.A OG VAL 358.A O no hydrogen 2.482 N/A GLN 389.A N SER 385.A O no hydrogen 3.316 N/A GLN 389.A NE2 GLN 262.A O no hydrogen 2.539 N/A GLN 389.A NE2 PHE 384.A O no hydrogen 2.893 N/A GLN 389.A NE2 SER 385.A O no hydrogen 3.640 N/A VAL 390.A N ARG 386.A O no hydrogen 2.909 N/A GLU 391.A N GLN 387.A O no hydrogen 2.908 N/A ILE 392.A N ALA 388.A O no hydrogen 2.908 N/A ILE 393.A N GLN 389.A O no hydrogen 2.933 N/A ASP 394.A N VAL 390.A O no hydrogen 2.904 N/A ASP 395.A N GLU 391.A O no hydrogen 3.275 N/A GLN 396.A N ILE 393.A O no hydrogen 3.367 N/A TYR 397.A N ILE 392.A O no hydrogen 2.935 N/A VAL 399.A N TYR 397.A O no hydrogen 3.073 N/A VAL 400.A N GLY 376.A O no hydrogen 2.906 N/A ILE 402.A N TYR 378.A O no hydrogen 2.909 N/A GLY 405.A N GLN 267.A O no hydrogen 2.621 N/A THR 406.A OG1 ALA 403.A O no hydrogen 3.329 N/A ALA 408.A N GLY 404.A O no hydrogen 3.279 N/A ALA 409.A N GLY 405.A O no hydrogen 2.897 N/A THR 410.A N THR 406.A O no hydrogen 2.936 N/A VAL 411.A N LEU 407.A O no hydrogen 2.907 N/A ARG 412.A N ALA 408.A O no hydrogen 2.912 N/A ARG 413.A N ALA 409.A O no hydrogen 2.916 N/A MET 414.A N THR 410.A O no hydrogen 2.921 N/A VAL 415.A N VAL 411.A O no hydrogen 2.898 N/A GLN 416.A N ARG 412.A O no hydrogen 2.927 N/A ALA 417.A N ARG 413.A O no hydrogen 3.301 N/A ALA 417.A N MET 414.A O no hydrogen 3.244 N/A ASN 418.A ND2 MET 414.A O no hydrogen 3.304 N/A GLY 421.A N VAL 415.A O no hydrogen 3.117 N/A ASP 424.A N ASP 422.A OD1 no hydrogen 3.272 N/A LEU 427.A N LEU 423.A O no hydrogen 2.911 N/A ALA 428.A N ASP 424.A O no hydrogen 2.912 N/A SER 429.A N ALA 425.A O no hydrogen 2.905 N/A SER 429.A OG GLU 433.A OE2 no hydrogen 3.145 N/A THR 430.A N LEU 426.A O no hydrogen 2.912 N/A THR 430.A OG1 TYR 286.A OH no hydrogen 2.578 N/A THR 430.A OG1 LEU 426.A O no hydrogen 3.562 N/A THR 430.A OG1 LEU 427.A O no hydrogen 2.364 N/A VAL 431.A N LEU 427.A O no hydrogen 2.926 N/A ASP 432.A N ALA 428.A O no hydrogen 2.909 N/A ALA 436.A N GLU 433.A O no hydrogen 3.269 N/A ALA 437.A N GLU 433.A O no hydrogen 3.494 N/A THR 439.A N LEU 317.A O no hydrogen 3.106 N/A GLU 445.A N ARG 442.A O no hydrogen 2.925 N/A SER 448.A N GLU 445.A O no hydrogen 3.233 N/A SER 448.A OG GLU 445.A O no hydrogen 2.422 N/A