Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4r6f_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 2.A N GLN 36.A OE1 no hydrogen 2.768 N/A THR 6.A N VAL 34.A O no hydrogen 3.055 N/A THR 6.A OG1 VAL 4.A O no hydrogen 2.711 N/A ILE 8.A N ASP 32.A O no hydrogen 2.934 N/A LYS 9.A N VAL 30.A O no hydrogen 2.939 N/A GLN 10.A N PRO 7.A O no hydrogen 2.977 N/A ILE 11.A N ILE 8.A O no hydrogen 2.956 N/A PHE 12.A N ILE 8.A O no hydrogen 2.963 N/A PHE 17.A N ASP 14.A OD1 no hydrogen 2.941 N/A ALA 18.A N ASP 14.A O no hydrogen 2.836 N/A GLU 19.A N ASP 15.A O no hydrogen 3.117 N/A THR 20.A N ALA 16.A O no hydrogen 3.021 N/A THR 20.A OG1 ALA 16.A O no hydrogen 3.048 N/A ILE 21.A N PHE 17.A O no hydrogen 2.965 N/A LYS 22.A N ALA 18.A O no hydrogen 2.933 N/A LYS 22.A NZ GLU 19.A OE1 no hydrogen 2.776 N/A ALA 23.A N GLU 19.A O no hydrogen 2.909 N/A ASN 24.A N THR 20.A O no hydrogen 2.958 N/A ASN 24.A ND2 GLN 44.A O no hydrogen 2.875 N/A LEU 25.A N ILE 21.A O no hydrogen 2.982 N/A LYS 26.A N ALA 23.A O no hydrogen 3.100 N/A LYS 27.A N LYS 22.A O no hydrogen 2.972 N/A LYS 27.A NZ GLU 38.A OE2 no hydrogen 2.687 N/A SER 29.A N ASP 32.A OD2 no hydrogen 2.977 N/A SER 29.A OG THR 31.A OG1 no hydrogen 2.772 N/A THR 31.A N SER 29.A OG no hydrogen 3.002 N/A THR 31.A OG1 SER 29.A OG no hydrogen 2.772 N/A ASP 32.A N SER 29.A O no hydrogen 3.133 N/A VAL 34.A N THR 6.A O no hydrogen 2.802 N/A THR 35.A N GLU 38.A OE1 no hydrogen 3.219 N/A THR 35.A OG1 GLU 38.A OE1 no hydrogen 3.352 N/A GLN 36.A NE2 ASN 40.A OD1 no hydrogen 3.023 N/A GLN 36.A NE2 TYR 60.A O no hydrogen 2.980 N/A GLU 38.A N THR 35.A O no hydrogen 3.062 N/A GLU 38.A N THR 35.A OG1 no hydrogen 3.089 N/A LEU 39.A N THR 35.A O no hydrogen 3.123 N/A ASN 40.A N GLN 36.A O no hydrogen 2.686 N/A SER 41.A N GLU 38.A O no hydrogen 3.166 N/A SER 41.A OG GLU 38.A O no hydrogen 2.608 N/A ILE 42.A N LEU 39.A O no hydrogen 3.185 N/A ILE 45.A N TYR 66.A O no hydrogen 2.896 N/A ALA 47.A N ALA 68.A O no hydrogen 2.862 N/A ASN 49.A N GLY 70.A O no hydrogen 2.694 N/A SER 50.A N ASN 72.A OD1 no hydrogen 2.831 N/A SER 50.A OG ASN 48.A O no hydrogen 3.024 N/A ILE 52.A N ASN 72.A OD1 no hydrogen 2.978 N/A LYS 53.A N ASP 14.A OD2 no hydrogen 2.953 N/A GLN 56.A N SER 54.A OG no hydrogen 3.034 N/A GLY 57.A N GLN 59.A OE1 no hydrogen 2.798 N/A ILE 58.A N VAL 55.A O no hydrogen 2.971 N/A GLN 59.A N GLN 59.A OE1 no hydrogen 2.803 N/A GLN 59.A NE2 GLN 56.A OE1 no hydrogen 2.965 N/A TYR 60.A N GLY 57.A O no hydrogen 2.933 N/A LEU 61.A N ILE 58.A O no hydrogen 2.927 N/A ASN 63.A ND2 ASN 40.A O no hydrogen 2.898 N/A VAL 64.A N LEU 61.A O no hydrogen 3.040 N/A ARG 65.A N ASP 43.A O no hydrogen 2.843 N/A ARG 65.A NH1 ASP 43.A OD2 no hydrogen 2.758 N/A ARG 65.A NH2 ASP 43.A OD2 no hydrogen 3.088 N/A ARG 65.A NH2 GLN 44.A OE1 no hydrogen 3.038 N/A TYR 66.A N ASP 43.A O no hydrogen 3.283 N/A LEU 67.A N TRP 88.A O no hydrogen 2.855 N/A ALA 68.A N ILE 45.A O no hydrogen 2.862 N/A LEU 69.A N ASN 90.A O no hydrogen 2.778 N/A GLY 70.A N ASN 48.A OD1 no hydrogen 2.820 N/A GLY 71.A N SER 92.A O.A no hydrogen 2.882 N/A GLY 71.A N SER 92.A O.B no hydrogen 2.848 N/A ASN 72.A ND2 ALA 47.A O no hydrogen 2.982 N/A ASN 72.A ND2 LEU 69.A O no hydrogen 3.001 N/A LYS 73.A N ILE 52.A O no hydrogen 2.722 N/A LEU 74.A N ASN 94.A OD1 no hydrogen 3.000 N/A SER 78.A N ASP 76.A OD2 no hydrogen 2.898 N/A SER 78.A OG ASP 76.A OD2 no hydrogen 2.645 N/A LEU 80.A N ILE 77.A O no hydrogen 2.950 N/A LYS 81.A N SER 78.A O no hydrogen 3.210 N/A LYS 81.A NZ GLU 82.A OE2 no hydrogen 3.100 N/A LEU 83.A N LEU 80.A O no hydrogen 3.077 N/A ASN 85.A ND2 PRO 62.A O no hydrogen 3.025 N/A LEU 86.A N LEU 83.A O no hydrogen 3.076 N/A GLY 87.A N ARG 65.A O no hydrogen 2.819 N/A TRP 88.A N ARG 65.A O no hydrogen 3.064 N/A LEU 89.A N THR 112.A O no hydrogen 2.928 N/A ASN 90.A N LEU 67.A O no hydrogen 2.857 N/A LEU 91.A N ASN 114.A O no hydrogen 2.786 N/A SER 92.A N.A ASN 90.A OD1 no hydrogen 2.919 N/A SER 92.A N.B ASN 90.A OD1 no hydrogen 2.933 N/A SER 92.A OG.A SER 116.A O no hydrogen 3.150 N/A SER 92.A OG.A SER 116.A OG no hydrogen 2.771 N/A SER 92.A OG.B ASN 90.A OD1 no hydrogen 2.884 N/A ASN 93.A N SER 116.A O no hydrogen 2.833 N/A ASN 94.A N ASN 118.A OD1 no hydrogen 3.087 N/A ASN 94.A ND2 LEU 69.A O no hydrogen 2.903 N/A ASN 94.A ND2 LEU 91.A O no hydrogen 3.083 N/A GLN 95.A N LEU 74.A O no hydrogen 2.827 N/A LEU 96.A N ASN 118.A OD1 no hydrogen 3.126 N/A VAL 103.A N PRO 100.A O no hydrogen 3.092 N/A GLU 105.A N GLY 102.A O no hydrogen 2.992 N/A LEU 107.A N PHE 104.A O no hydrogen 3.253 N/A ASN 109.A ND2 THR 84.A O no hydrogen 2.945 N/A LEU 110.A N LEU 107.A O no hydrogen 3.130 N/A THR 111.A N GLY 87.A O no hydrogen 2.716 N/A THR 111.A OG1 GLY 87.A O no hydrogen 3.124 N/A THR 111.A OG1 THR 112.A OG1 no hydrogen 3.386 N/A THR 112.A N GLY 87.A O no hydrogen 3.368 N/A THR 112.A OG1 THR 111.A OG1 no hydrogen 3.386 N/A LEU 113.A N THR 136.A O no hydrogen 2.951 N/A ASN 114.A N LEU 89.A O no hydrogen 2.964 N/A LEU 115.A N ASN 138.A O no hydrogen 2.725 N/A SER 116.A N ASN 114.A OD1 no hydrogen 2.965 N/A SER 116.A OG SER 92.A OG.A no hydrogen 2.771 N/A SER 116.A OG ASN 114.A OD1 no hydrogen 2.797 N/A ASN 117.A N SER 140.A O no hydrogen 2.812 N/A ASN 117.A ND2 SER 116.A OG no hydrogen 3.334 N/A ASN 118.A ND2 LEU 91.A O no hydrogen 2.961 N/A ASN 118.A ND2 LEU 115.A O no hydrogen 3.100 N/A GLN 119.A N LEU 96.A O no hydrogen 2.800 N/A GLN 119.A NE2 ASN 94.A O no hydrogen 3.160 N/A LEU 120.A N ASN 142.A OD1 no hydrogen 3.037 N/A VAL 127.A N PRO 124.A O no hydrogen 3.152 N/A GLU 129.A N GLY 126.A O no hydrogen 3.105 N/A ARG 130.A NE GLU 105.A OE2 no hydrogen 2.845 N/A ARG 130.A NH2 GLU 105.A OE2 no hydrogen 3.537 N/A LEU 131.A N PHE 128.A O no hydrogen 3.118 N/A ALA 132.A N ARG 130.A O no hydrogen 2.951 N/A SER 133.A OG THR 108.A O no hydrogen 2.928 N/A LEU 134.A N LEU 131.A O no hydrogen 3.128 N/A THR 135.A N THR 111.A O no hydrogen 2.774 N/A THR 135.A OG1 THR 111.A O no hydrogen 3.053 N/A THR 136.A N THR 111.A O no hydrogen 3.027 N/A LEU 137.A N THR 160.A O no hydrogen 3.025 N/A ASN 138.A N LEU 113.A O no hydrogen 3.034 N/A LEU 139.A N ASN 162.A O no hydrogen 2.881 N/A SER 140.A N ASN 138.A OD1 no hydrogen 2.989 N/A SER 140.A OG ASN 138.A OD1 no hydrogen 3.180 N/A ASN 141.A N SER 164.A O no hydrogen 2.877 N/A ASN 141.A ND2 SER 140.A OG no hydrogen 3.020 N/A ASN 142.A N HIS 165.A O no hydrogen 3.226 N/A ASN 142.A ND2 LEU 115.A O no hydrogen 3.022 N/A ASN 142.A ND2 LEU 139.A O no hydrogen 3.079 N/A ASN 143.A N LEU 120.A O no hydrogen 2.794 N/A ILE 144.A N ASN 166.A OD1 no hydrogen 2.943 N/A ALA 145.A N THR 121.A O no hydrogen 2.956 N/A ASN 148.A ND2 GLN 125.A OE1 no hydrogen 2.416 N/A GLN 150.A N.A ASN 148.A OD1 no hydrogen 3.099 N/A GLN 150.A N.B ASN 148.A OD1 no hydrogen 3.075 N/A GLN 150.A NE2.A ASP 149.A OD1 no hydrogen 3.269 N/A MET 151.A N ASN 148.A O no hydrogen 3.140 N/A GLU 153.A N GLN 150.A O.B no hydrogen 2.843 N/A LEU 155.A N LEU 152.A O no hydrogen 3.158 N/A ASN 157.A ND2 ALA 132.A O no hydrogen 2.981 N/A LEU 158.A N LEU 155.A O no hydrogen 3.053 N/A THR 159.A N THR 135.A O no hydrogen 2.816 N/A THR 159.A OG1 THR 135.A O no hydrogen 3.055 N/A THR 160.A N THR 135.A O no hydrogen 2.968 N/A LEU 161.A N THR 192.A O no hydrogen 2.927 N/A ASN 162.A N LEU 137.A O no hydrogen 2.999 N/A LEU 163.A N ASN 194.A O no hydrogen 2.853 N/A SER 164.A N ASN 162.A OD1 no hydrogen 2.992 N/A SER 164.A OG ASN 162.A OD1 no hydrogen 2.830 N/A HIS 165.A N SER 196.A O no hydrogen 2.949 N/A ASN 166.A N SER 197.A O no hydrogen 3.255 N/A ASN 166.A ND2 LEU 139.A O no hydrogen 2.924 N/A ASN 166.A ND2 LEU 163.A O no hydrogen 3.129 N/A ASN 167.A N ILE 144.A O no hydrogen 2.820 N/A LEU 168.A N ASN 198.A OD1 no hydrogen 3.089 N/A LEU 171.A N LEU 168.A O no hydrogen 2.950 N/A TRP 172.A N ALA 169.A O no hydrogen 3.170 N/A TRP 172.A NE1 ILE 181.A O no hydrogen 2.907 N/A LYS 173.A N ARG 170.A O no hydrogen 3.388 N/A LYS 173.A NZ ASP 201.A OD1 no hydrogen 3.142 N/A LYS 173.A NZ ASP 201.A OD2 no hydrogen 3.174 N/A HIS 174.A N GLU 202.A OE1 no hydrogen 2.797 N/A HIS 174.A ND1 GLU 202.A OE1 no hydrogen 2.686 N/A ASN 176.A N LYS 173.A O no hydrogen 2.930 N/A ASN 176.A ND2 GLY 179.A O no hydrogen 3.102 N/A GLY 179.A N ASN 176.A O no hydrogen 2.787 N/A ILE 181.A N LEU 171.A O no hydrogen 2.840 N/A TYR 182.A OH ARG 205.A O no hydrogen 2.820 N/A LYS 185.A N TYR 182.A O no hydrogen 3.411 N/A GLY 186.A N ASP 210.A OD2 no hydrogen 2.765 N/A THR 188.A N GLY 186.A O no hydrogen 2.935 N/A ASN 189.A ND2 THR 156.A O no hydrogen 2.678 N/A LEU 190.A N LEU 187.A O no hydrogen 3.177 N/A THR 191.A N THR 159.A O no hydrogen 2.816 N/A THR 191.A OG1 THR 159.A O no hydrogen 3.162 N/A THR 192.A N THR 159.A O no hydrogen 3.021 N/A LEU 193.A N THR 216.A O no hydrogen 3.009 N/A ASN 194.A N LEU 161.A O no hydrogen 3.001 N/A LEU 195.A N ASN 218.A O no hydrogen 2.807 N/A SER 196.A N ASN 194.A OD1 no hydrogen 2.924 N/A SER 196.A OG ASN 194.A OD1 no hydrogen 2.782 N/A SER 197.A N SER 220.A O no hydrogen 3.062 N/A ASN 198.A N ASN 222.A OD1 no hydrogen 2.804 N/A ASN 198.A ND2 LEU 163.A O no hydrogen 2.917 N/A ASN 198.A ND2 LEU 195.A O no hydrogen 3.416 N/A ASN 198.A ND2 SER 196.A O no hydrogen 3.217 N/A PHE 200.A N ASN 222.A OD1 no hydrogen 3.042 N/A VAL 207.A N PRO 204.A O no hydrogen 3.238 N/A LYS 209.A N GLU 206.A O no hydrogen 3.112 N/A LEU 211.A N PHE 208.A O no hydrogen 3.083 N/A SER 213.A OG THR 188.A O no hydrogen 2.689 N/A LEU 214.A N LEU 211.A O no hydrogen 3.056 N/A THR 215.A N THR 191.A O no hydrogen 2.827 N/A THR 215.A OG1 THR 191.A O no hydrogen 3.157 N/A THR 216.A N THR 191.A O no hydrogen 2.983 N/A LEU 217.A N THR 240.A O no hydrogen 2.973 N/A ASN 218.A N LEU 193.A O no hydrogen 2.963 N/A LEU 219.A N ASN 242.A O no hydrogen 2.830 N/A SER 220.A N ASN 218.A OD1 no hydrogen 2.918 N/A SER 220.A OG ASN 218.A OD1 no hydrogen 2.866 N/A ASN 221.A N SER 244.A O no hydrogen 2.869 N/A ASN 221.A ND2 SER 220.A OG no hydrogen 3.212 N/A ASN 222.A ND2 LEU 195.A O no hydrogen 3.132 N/A ASN 222.A ND2 LEU 219.A O no hydrogen 3.045 N/A ASN 223.A N PHE 200.A O no hydrogen 2.757 N/A ASN 223.A ND2 GLY 199.A O no hydrogen 3.307 N/A ILE 224.A N ASN 246.A OD1 no hydrogen 2.963 N/A GLN 230.A N ASN 228.A OD1 no hydrogen 2.697 N/A GLN 230.A NE2 GLU 233.A OE2 no hydrogen 2.956 N/A MET 231.A N ASN 228.A O no hydrogen 3.515 N/A GLU 233.A N GLN 230.A O no hydrogen 3.021 N/A LEU 235.A N LEU 232.A O no hydrogen 3.392 N/A THR 236.A OG1 ASN 237.A OD1 no hydrogen 3.521 N/A ASN 237.A ND2 THR 212.A O no hydrogen 3.085 N/A LEU 238.A N LEU 235.A O no hydrogen 3.309 N/A THR 239.A N THR 215.A O no hydrogen 2.781 N/A THR 239.A OG1 THR 215.A O no hydrogen 3.277 N/A THR 240.A N THR 215.A O no hydrogen 2.885 N/A LEU 241.A N THR 272.A O no hydrogen 2.972 N/A ASN 242.A N LEU 217.A O no hydrogen 2.958 N/A LEU 243.A N ASN 274.A O no hydrogen 2.845 N/A SER 244.A N ASN 242.A OD1 no hydrogen 3.035 N/A SER 244.A OG ASN 242.A OD1 no hydrogen 2.781 N/A HIS 245.A N SER 276.A O no hydrogen 2.966 N/A ASN 246.A N SER 277.A O no hydrogen 3.298 N/A ASN 246.A ND2 LEU 219.A O no hydrogen 2.953 N/A ASN 246.A ND2 LEU 243.A O no hydrogen 3.077 N/A ASN 247.A N ILE 224.A O no hydrogen 2.903 N/A LEU 248.A N ASN 278.A OD1 no hydrogen 3.077 N/A ALA 249.A N ASN 278.A O no hydrogen 3.272 N/A LEU 251.A N LEU 248.A O no hydrogen 2.921 N/A TRP 252.A N ALA 249.A O no hydrogen 3.063 N/A TRP 252.A NE1 ILE 261.A O no hydrogen 3.128 N/A LYS 253.A N ARG 250.A O no hydrogen 3.181 N/A LYS 253.A NZ ASP 281.A OD1 no hydrogen 3.030 N/A LYS 253.A NZ ASP 281.A OD2 no hydrogen 2.769 N/A LYS 253.A NZ GLU 282.A OE2 no hydrogen 3.013 N/A HIS 254.A N GLU 282.A OE1 no hydrogen 2.811 N/A HIS 254.A ND1 GLU 282.A OE1 no hydrogen 2.874 N/A ASN 256.A N LYS 253.A O no hydrogen 2.983 N/A ASN 256.A ND2 GLY 259.A O no hydrogen 3.085 N/A GLY 259.A N ASN 256.A O no hydrogen 2.652 N/A ILE 261.A N LEU 251.A O no hydrogen 2.885 N/A LYS 265.A N TYR 262.A O no hydrogen 3.285 N/A LYS 265.A NZ ASP 229.A OD2 no hydrogen 2.870 N/A GLY 266.A N ASP 290.A OD2 no hydrogen 2.825 N/A LEU 267.A N LEU 264.A O no hydrogen 3.477 N/A THR 268.A N GLY 266.A O no hydrogen 2.880 N/A ASN 269.A ND2 THR 236.A O no hydrogen 2.725 N/A LEU 270.A N LEU 267.A O no hydrogen 3.239 N/A THR 271.A N THR 239.A O no hydrogen 2.853 N/A THR 271.A OG1 THR 239.A O no hydrogen 3.118 N/A THR 272.A N THR 239.A O no hydrogen 3.027 N/A LEU 273.A N THR 296.A O no hydrogen 2.998 N/A ASN 274.A N LEU 241.A O no hydrogen 3.013 N/A LEU 275.A N ASN 298.A O no hydrogen 2.826 N/A SER 276.A N ASN 274.A OD1 no hydrogen 3.015 N/A SER 276.A OG ASN 274.A OD1 no hydrogen 2.640 N/A SER 277.A N SER 300.A O no hydrogen 3.060 N/A ASN 278.A N ASN 302.A OD1 no hydrogen 2.828 N/A ASN 278.A ND2 LEU 243.A O no hydrogen 2.950 N/A ASN 278.A ND2 LEU 275.A O no hydrogen 3.424 N/A ASN 278.A ND2 SER 276.A O no hydrogen 3.239 N/A PHE 280.A N ASN 302.A OD1 no hydrogen 3.021 N/A ARG 285.A NH1 ARG 285.A O no hydrogen 3.289 N/A VAL 287.A N PRO 284.A O no hydrogen 3.230 N/A LYS 289.A N GLU 286.A O no hydrogen 3.180 N/A LYS 289.A NZ ASP 290.A OD1 no hydrogen 3.069 N/A LEU 291.A N PHE 288.A O no hydrogen 3.046 N/A THR 292.A N ASP 290.A O no hydrogen 2.942 N/A THR 292.A OG1 ASP 290.A O no hydrogen 3.454 N/A SER 293.A OG THR 268.A O no hydrogen 2.639 N/A LEU 294.A N LEU 291.A O no hydrogen 3.047 N/A THR 295.A N THR 271.A O no hydrogen 2.838 N/A THR 295.A OG1 SER 293.A O no hydrogen 2.798 N/A THR 296.A N THR 271.A O no hydrogen 2.920 N/A LEU 297.A N THR 320.A O no hydrogen 2.872 N/A ASN 298.A N LEU 273.A O no hydrogen 2.917 N/A LEU 299.A N ASN 322.A O no hydrogen 2.805 N/A SER 300.A N ASN 298.A OD1 no hydrogen 2.954 N/A SER 300.A OG ASN 298.A OD1 no hydrogen 2.649 N/A ASN 301.A N SER 324.A O no hydrogen 2.853 N/A ASN 302.A ND2 LEU 275.A O no hydrogen 3.123 N/A ASN 302.A ND2 LEU 299.A O no hydrogen 3.031 N/A GLN 303.A N PHE 280.A O no hydrogen 2.678 N/A LEU 304.A N ASN 326.A OD1 no hydrogen 3.083 N/A GLN 309.A N GLN 309.A OE1 no hydrogen 2.499 N/A VAL 311.A N PRO 308.A O no hydrogen 3.310 N/A GLU 313.A N GLY 310.A O no hydrogen 3.034 N/A LEU 315.A N PHE 312.A O no hydrogen 3.173 N/A ASN 317.A ND2 THR 292.A O no hydrogen 2.933 N/A LEU 318.A N LEU 315.A O no hydrogen 3.231 N/A LYS 319.A N THR 295.A O no hydrogen 2.754 N/A THR 320.A N THR 295.A O no hydrogen 2.935 N/A ASN 322.A N LEU 297.A O no hydrogen 2.916 N/A SER 324.A N ASN 322.A OD1 no hydrogen 3.019 N/A SER 324.A OG ASN 322.A OD1 no hydrogen 2.655 N/A ASN 325.A ND2 ASN 301.A OD1 no hydrogen 2.773 N/A ASN 326.A ND2 LEU 299.A O no hydrogen 3.018 N/A ASN 326.A ND2 LEU 323.A O no hydrogen 2.939 N/A GLN 327.A N LEU 304.A O no hydrogen 2.821 N/A GLN 327.A NE2 ASN 302.A O no hydrogen 3.355 N/A GLN 327.A NE2 GLN 303.A OE1 no hydrogen 3.521 N/A