Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4r6y_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 6.A N THR 36.A O no hydrogen 2.945 N/A THR 7.A N ASP 61.A OD2 no hydrogen 2.741 N/A VAL 8.A N ARG 38.A O no hydrogen 2.880 N/A TYR 9.A N VAL 62.A O no hydrogen 2.907 N/A TYR 9.A OH GLU 54.A OE1 no hydrogen 2.635 N/A TYR 9.A OH GLU 54.A OE2 no hydrogen 3.277 N/A SER 10.A N VAL 40.A O no hydrogen 2.872 N/A SER 10.A OG ILE 11.A O no hydrogen 2.766 N/A SER 10.A OG TYR 22.A OH no hydrogen 2.811 N/A ILE 11.A N VAL 64.A O no hydrogen 2.861 N/A ASP 12.A N GLY 42.A O no hydrogen 3.244 N/A HIS 15.A ND1 HIS 15.A O no hydrogen 2.749 N/A GLY 17.A N HIS 15.A O no hydrogen 2.984 N/A SER 20.A N GLY 17.A O no hydrogen 3.051 N/A SER 20.A OG LEU 14.A O no hydrogen 3.477 N/A SER 20.A OG GLY 17.A O no hydrogen 2.726 N/A TRP 21.A N SER 264.A OG.B no hydrogen 2.939 N/A TRP 21.A NE1 ALA 256.A O no hydrogen 2.873 N/A TYR 22.A N LEU 14.A O no hydrogen 2.904 N/A TYR 22.A OH SER 10.A OG no hydrogen 2.811 N/A GLN 23.A N SER 20.A OG no hydrogen 3.233 N/A VAL 24.A N SER 20.A O no hydrogen 2.951 N/A GLN 25.A N TRP 21.A O no hydrogen 2.880 N/A PHE 26.A N TYR 22.A O no hydrogen 2.738 N/A ASP 27.A N GLN 23.A O no hydrogen 2.929 N/A ALA 28.A N VAL 24.A O no hydrogen 2.952 N/A PHE 29.A N GLN 25.A O no hydrogen 2.822 N/A THR 30.A N PHE 26.A O no hydrogen 2.895 N/A THR 30.A OG1 PHE 26.A O no hydrogen 3.065 N/A THR 30.A OG1 ILE 35.A O no hydrogen 2.677 N/A LYS 31.A N ASP 27.A O no hydrogen 2.935 N/A ALA 32.A N ALA 28.A O no hydrogen 2.987 N/A THR 33.A N PHE 29.A O no hydrogen 2.902 N/A THR 33.A OG1 PHE 29.A O no hydrogen 2.767 N/A GLY 34.A N THR 30.A O no hydrogen 2.845 N/A ILE 35.A N THR 33.A OG1 no hydrogen 3.030 N/A THR 36.A N SER 4.A O no hydrogen 2.837 N/A THR 36.A OG1 GLU 3.A OE2 no hydrogen 2.645 N/A ARG 38.A N VAL 6.A O no hydrogen 2.809 N/A TYR 39.A OH GLU 41.A OE1 no hydrogen 2.630 N/A VAL 40.A N VAL 8.A O no hydrogen 2.897 N/A GLY 42.A N SER 10.A O no hydrogen 3.048 N/A VAL 47.A N GLY 43.A O no hydrogen 3.075 N/A GLU 49.A N GLY 45.A O no hydrogen 2.818 N/A ARG 50.A N VAL 46.A O no hydrogen 2.954 N/A ARG 50.A NE GLU 54.A OE2 no hydrogen 2.901 N/A LEU 51.A N VAL 47.A O no hydrogen 3.138 N/A ALA 52.A N VAL 48.A O no hydrogen 3.023 N/A LYS 53.A N GLU 49.A O no hydrogen 2.870 N/A GLU 54.A N ARG 50.A O no hydrogen 2.949 N/A GLU 54.A N LEU 51.A O no hydrogen 3.135 N/A ARG 55.A N ALA 52.A O no hydrogen 3.263 N/A ARG 55.A NH1 GLU 76.A O no hydrogen 3.023 N/A ARG 55.A NH2 GLU 76.A O no hydrogen 2.870 N/A ASN 57.A N GLU 54.A O no hydrogen 2.925 N/A GLN 59.A NE2 ASN 57.A O no hydrogen 3.023 N/A ASP 61.A N THR 7.A O no hydrogen 2.828 N/A VAL 62.A N THR 7.A O no hydrogen 3.058 N/A LEU 63.A N GLY 233.A O no hydrogen 2.937 N/A VAL 64.A N TYR 9.A O no hydrogen 2.935 N/A THR 65.A N VAL 231.A O no hydrogen 2.937 N/A THR 65.A OG1 GLY 44.A O no hydrogen 2.791 N/A ALA 66.A N THR 65.A OG1 no hydrogen 2.826 N/A PHE 69.A N ALA 66.A O no hydrogen 2.883 N/A ILE 70.A N ALA 66.A O no hydrogen 3.245 N/A GLN 71.A NE2 TYR 97.A OH no hydrogen 3.549 N/A ARG 72.A N PRO 68.A O no hydrogen 2.905 N/A ARG 72.A NE ALA 301.A O no hydrogen 3.307 N/A ARG 72.A NH2 ALA 301.A O no hydrogen 2.950 N/A ALA 73.A N PHE 69.A O no hydrogen 2.919 N/A ALA 74.A N ILE 70.A O no hydrogen 3.030 N/A ALA 75.A N GLN 71.A O no hydrogen 2.879 N/A GLU 76.A N ARG 72.A O no hydrogen 2.918 N/A LYS 77.A N ALA 74.A O no hydrogen 3.014 N/A LEU 78.A N ALA 73.A O no hydrogen 2.951 N/A ALA 80.A N LEU 234.A O no hydrogen 2.780 N/A ASN 81.A ND2 ASN 95.A OD1 no hydrogen 2.854 N/A PHE 82.A N ASN 95.A O no hydrogen 2.823 N/A ASP 85.A N ASN 249.A OD1 no hydrogen 2.930 N/A SER 88.A OG THR 86.A O no hydrogen 3.006 N/A ALA 89.A N THR 86.A O no hydrogen 2.505 N/A ILE 90.A N ALA 87.A O no hydrogen 2.507 N/A ALA 93.A N ILE 90.A O no hydrogen 3.413 N/A ASN 94.A N TYR 97.A O no hydrogen 2.951 N/A LEU 96.A N ASN 94.A OD1 no hydrogen 2.822 N/A TYR 97.A N ASN 94.A OD1 no hydrogen 2.988 N/A SER 98.A N ILE 232.A O no hydrogen 2.917 N/A SER 98.A OG.B PRO 99.A O no hydrogen 2.941 N/A LEU 100.A N TYR 230.A O no hydrogen 2.768 N/A VAL 101.A N TYR 230.A O no hydrogen 3.337 N/A LYS 102.A N MET 267.A O no hydrogen 2.784 N/A ASN 103.A ND2 ASP 197.A OD1 no hydrogen 2.927 N/A LEU 105.A N LEU 226.A O no hydrogen 2.976 N/A SER 106.A N GLY 196.A O no hydrogen 3.183 N/A SER 106.A OG ASN 201.A OD1 no hydrogen 2.709 N/A PHE 107.A N PHE 214.A O no hydrogen 3.128 N/A ILE 108.A N ALA 194.A O no hydrogen 2.906 N/A TYR 109.A N LYS 212.A O no hydrogen 2.877 N/A ASN 110.A N TYR 192.A O no hydrogen 2.895 N/A ASN 110.A ND2 VAL 186.A O no hydrogen 2.804 N/A SER 111.A N ASN 210.A O no hydrogen 2.864 N/A SER 111.A OG ASN 210.A O no hydrogen 3.346 N/A LEU 113.A N ASN 110.A OD1 no hydrogen 2.853 N/A LEU 114.A N ASN 110.A O no hydrogen 2.966 N/A LYS 115.A NZ SER 111.A O no hydrogen 3.481 N/A LYS 115.A NZ LYS 112.A O no hydrogen 3.494 N/A ALA 119.A N ASP 123.A OD2 no hydrogen 3.147 N/A SER 120.A N ASP 123.A OD2 no hydrogen 3.077 N/A TRP 121.A N ALA 217.A O no hydrogen 3.037 N/A ASP 123.A N SER 120.A OG no hydrogen 2.983 N/A LEU 124.A N TRP 121.A O no hydrogen 3.133 N/A LEU 125.A N GLN 122.A O no hydrogen 2.975 N/A ASP 126.A N ASP 123.A O no hydrogen 3.013 N/A LYS 128.A N ASP 126.A OD1 no hydrogen 2.894 N/A PHE 129.A N ASP 126.A O no hydrogen 3.009 N/A LYS 130.A N GLY 127.A O no hydrogen 2.995 N/A ASN 131.A N ASN 171.A O no hydrogen 2.885 N/A LYS 132.A N PHE 129.A O no hydrogen 2.837 N/A LYS 132.A NZ GLY 189.A O no hydrogen 2.993 N/A LYS 132.A NZ GLU 190.A O no hydrogen 3.435 N/A GLN 134.A N VAL 193.A O no hydrogen 3.053 N/A GLN 134.A NE2 GLY 174.A O no hydrogen 2.987 N/A TYR 135.A N ASN 172.A OD1 no hydrogen 3.226 N/A SER 136.A N ASN 195.A OD1 no hydrogen 3.074 N/A SER 136.A OG THR 179.A OG1 no hydrogen 2.672 N/A THR 137.A N SER 176.A O no hydrogen 2.893 N/A THR 137.A OG1 SER 176.A O no hydrogen 3.197 N/A GLY 139.A N THR 145.A OG1 no hydrogen 2.782 N/A GLN 140.A N THR 137.A O no hydrogen 3.124 N/A ALA 141.A N THR 137.A O no hydrogen 2.924 N/A THR 145.A N ALA 141.A O no hydrogen 2.981 N/A THR 145.A OG1 ALA 141.A O no hydrogen 3.396 N/A ALA 146.A N ALA 142.A O no hydrogen 3.025 N/A VAL 147.A N ASP 143.A O no hydrogen 3.120 N/A MET 148.A N GLY 144.A O no hydrogen 3.198 N/A LEU 149.A N THR 145.A O no hydrogen 3.098 N/A GLN 150.A N ALA 146.A O no hydrogen 2.828 N/A GLN 150.A NE2 SER 154.A OG no hydrogen 2.949 N/A GLN 150.A NE2 SER 224.A OG no hydrogen 2.935 N/A ALA 151.A N VAL 147.A O no hydrogen 2.864 N/A PHE 152.A N MET 148.A O no hydrogen 3.180 N/A HIS 153.A N LEU 149.A O no hydrogen 3.171 N/A SER 154.A N GLN 150.A O no hydrogen 2.800 N/A SER 154.A OG GLN 150.A O no hydrogen 3.385 N/A PHE 155.A N ALA 151.A O no hydrogen 3.011 N/A GLY 156.A N HIS 153.A O no hydrogen 3.254 N/A LYS 158.A NZ ASP 307.A OD2 no hydrogen 2.689 N/A ALA 160.A N SER 157.A OG no hydrogen 2.979 N/A GLY 161.A N SER 157.A O no hydrogen 2.933 N/A PHE 162.A N LYS 158.A O no hydrogen 2.807 N/A ALA 163.A N ASP 159.A O no hydrogen 2.913 N/A TYR 164.A N ALA 160.A O no hydrogen 3.061 N/A TYR 164.A OH TRP 121.A O no hydrogen 2.736 N/A LEU 165.A N GLY 161.A O no hydrogen 2.957 N/A GLY 166.A N PHE 162.A O no hydrogen 2.802 N/A LYS 167.A N ALA 163.A O no hydrogen 3.085 N/A LEU 168.A N TYR 164.A O no hydrogen 2.841 N/A GLN 169.A N LEU 165.A O no hydrogen 3.001 N/A GLN 169.A N GLY 166.A O no hydrogen 3.327 N/A ALA 170.A N LYS 167.A O no hydrogen 3.137 N/A ASN 171.A N LEU 168.A O no hydrogen 2.942 N/A ASN 171.A ND2 LEU 124.A O no hydrogen 2.933 N/A ASN 171.A ND2 ASP 126.A O no hydrogen 3.013 N/A ASN 172.A N LEU 168.A O no hydrogen 2.973 N/A ASN 172.A ND2 GLN 169.A OE1 no hydrogen 2.958 N/A VAL 173.A N LEU 133.A O no hydrogen 2.845 N/A SER 176.A N THR 137.A OG1 no hydrogen 3.030 N/A SER 176.A OG SER 178.A O no hydrogen 2.756 N/A THR 179.A OG1 SER 136.A OG no hydrogen 2.672 N/A LEU 182.A N THR 179.A O no hydrogen 2.869 N/A THR 183.A N GLY 180.A O no hydrogen 3.255 N/A THR 183.A OG1 GLY 180.A O no hydrogen 3.471 N/A THR 183.A OG1 GLN 204.A OE1 no hydrogen 2.743 N/A VAL 186.A N LEU 182.A O no hydrogen 2.991 N/A ASN 187.A N THR 183.A O no hydrogen 2.881 N/A LYS 188.A N ALA 184.A O no hydrogen 3.028 N/A GLY 189.A N VAL 186.A O no hydrogen 2.957 N/A ILE 191.A N LEU 185.A O no hydrogen 3.403 N/A TYR 192.A N LYS 132.A O no hydrogen 2.732 N/A ALA 194.A N ILE 108.A O no hydrogen 2.980 N/A ASN 195.A ND2 SER 136.A OG no hydrogen 2.967 N/A LEU 198.A N TYR 104.A O no hydrogen 2.834 N/A GLN 199.A N ASN 103.A OD1 no hydrogen 2.920 N/A GLN 199.A NE2 GLY 13.A O no hydrogen 2.928 N/A GLN 199.A NE2 SER 264.A O.A no hydrogen 2.827 N/A GLN 199.A NE2 SER 264.A O.B no hydrogen 2.804 N/A MET 200.A N ASP 197.A OD1 no hydrogen 3.162 N/A ASN 201.A N ASP 197.A O no hydrogen 2.872 N/A ASN 201.A ND2 GLN 204.A OE1 no hydrogen 2.958 N/A LEU 202.A N LEU 198.A O no hydrogen 2.828 N/A ALA 203.A N GLN 199.A O no hydrogen 3.366 N/A GLN 204.A N MET 200.A O no hydrogen 3.116 N/A GLN 204.A N ASN 201.A O no hydrogen 3.009 N/A GLN 204.A NE2 GLY 180.A O no hydrogen 3.093 N/A MET 205.A N LEU 202.A O no hydrogen 3.337 N/A ASN 208.A N MET 205.A O no hydrogen 3.081 N/A ASN 208.A ND2 GLN 204.A O no hydrogen 2.882 N/A ASN 210.A N ASN 187.A OD1 no hydrogen 2.845 N/A ASN 210.A ND2 ASN 187.A O no hydrogen 2.962 N/A VAL 211.A N ASN 208.A O no hydrogen 3.005 N/A LYS 212.A N TYR 109.A O no hydrogen 2.915 N/A PHE 214.A N PHE 107.A O no hydrogen 2.860 N/A TRP 215.A NE1 LEU 105.A O no hydrogen 2.815 N/A ALA 217.A N ALA 119.A O no hydrogen 2.885 N/A ASN 218.A N GLU 222.A O no hydrogen 2.926 N/A ASN 218.A ND2 SER 154.A O no hydrogen 3.225 N/A ASN 218.A ND2 GLU 222.A OE1.B no hydrogen 3.081 N/A LYS 220.A N ASN 218.A OD1 no hydrogen 2.975 N/A GLY 221.A N ASN 218.A O no hydrogen 2.931 N/A GLU 222.A N ASN 218.A OD1 no hydrogen 3.007 N/A ARG 223.A NH2 GLU 288.A O no hydrogen 3.108 N/A ALA 225.A N GLN 291.A O no hydrogen 2.884 N/A ALA 227.A N TRP 293.A O no hydrogen 2.923 N/A ILE 228.A N ASN 103.A O no hydrogen 2.848 N/A TYR 230.A N VAL 101.A O no hydrogen 2.865 N/A TYR 230.A OH GLN 199.A OE1 no hydrogen 2.624 N/A VAL 231.A N THR 65.A O no hydrogen 2.833 N/A ILE 232.A N SER 98.A O no hydrogen 2.819 N/A GLY 233.A N LEU 63.A O no hydrogen 2.917 N/A VAL 235.A N ASP 61.A O no hydrogen 2.883 N/A GLN 236.A N LEU 78.A O no hydrogen 2.824 N/A ALA 238.A N VAL 235.A O no hydrogen 3.161 N/A GLN 240.A N ASP 61.A OD1 no hydrogen 2.720 N/A ASN 243.A ND2 VAL 5.A O no hydrogen 2.919 N/A GLY 244.A N GLN 240.A O no hydrogen 2.841 N/A LYS 245.A N SER 241.A O no hydrogen 2.906 N/A LYS 245.A NZ GLU 242.A OE2 no hydrogen 3.243 N/A LYS 246.A N GLU 242.A O no hydrogen 3.147 N/A LEU 247.A N ASN 243.A O no hydrogen 2.944 N/A ILE 248.A N GLY 244.A O no hydrogen 2.900 N/A ASN 249.A N LYS 245.A O no hydrogen 2.989 N/A PHE 250.A N LYS 246.A O no hydrogen 2.940 N/A LEU 251.A N LEU 247.A O no hydrogen 2.858 N/A LEU 252.A N ILE 248.A O no hydrogen 3.092 N/A SER 253.A N PHE 250.A O no hydrogen 3.038 N/A SER 253.A OG PHE 250.A O no hydrogen 2.677 N/A ALA 256.A N SER 253.A OG no hydrogen 3.202 N/A GLN 257.A N SER 253.A O no hydrogen 2.885 N/A GLN 257.A NE2 LEU 100.A O no hydrogen 2.928 N/A GLN 257.A NE2 LEU 251.A O no hydrogen 3.040 N/A THR 258.A N LYS 254.A O no hydrogen 2.985 N/A THR 258.A OG1.A GLU 255.A O no hydrogen 2.756 N/A ARG 259.A N ALA 256.A O no hydrogen 3.116 N/A ARG 259.A NE GLU 262.A OE1 no hydrogen 2.824 N/A ARG 259.A NH2 GLU 262.A OE1 no hydrogen 3.561 N/A ARG 259.A NH2 GLU 262.A OE2 no hydrogen 2.887 N/A VAL 260.A N GLN 257.A O no hydrogen 3.267 N/A SER 261.A OG.A ASP 277.A OD1 no hydrogen 3.569 N/A SER 261.A OG.A ASP 277.A OD2 no hydrogen 2.859 N/A SER 261.A OG.B ASP 277.A OD1 no hydrogen 2.579 N/A SER 261.A OG.B ASP 277.A OD2 no hydrogen 3.434 N/A LEU 263.A N ARG 259.A O no hydrogen 2.979 N/A SER 264.A N.A VAL 260.A O no hydrogen 2.918 N/A SER 264.A N.B VAL 260.A O no hydrogen 2.957 N/A SER 264.A OG.A VAL 260.A O no hydrogen 2.726 N/A TRP 265.A N SER 261.A O no hydrogen 2.977 N/A GLY 266.A N SER 264.A OG.A no hydrogen 2.691 N/A MET 267.A N LYS 102.A O no hydrogen 3.411 N/A VAL 269.A N GLN 257.A OE1 no hydrogen 2.867 N/A ARG 270.A NE ASP 272.A OD1 no hydrogen 2.749 N/A ARG 270.A NH1 LEU 252.A O no hydrogen 2.897 N/A ARG 270.A NH2 ASP 272.A OD1 no hydrogen 3.479 N/A ARG 270.A NH2 ASP 272.A OD2 no hydrogen 2.885 N/A HIS 279.A ND1 SER 261.A O no hydrogen 2.897 N/A TYR 280.A N ASP 277.A OD2 no hydrogen 2.963 N/A LYS 281.A NZ GLU 278.A OE2 no hydrogen 2.783 N/A ALA 282.A N GLU 278.A O no hydrogen 3.246 N/A ALA 283.A N HIS 279.A O no hydrogen 3.010 N/A THR 284.A N TYR 280.A O no hydrogen 2.905 N/A THR 284.A OG1 TYR 280.A O no hydrogen 3.093 N/A ALA 285.A N LYS 281.A O no hydrogen 2.980 N/A ALA 286.A N ALA 282.A O no hydrogen 2.997 N/A LEU 287.A N ALA 283.A O no hydrogen 3.052 N/A GLU 288.A N ALA 285.A O no hydrogen 3.336 N/A VAL 290.A N LEU 287.A O no hydrogen 2.960 N/A GLN 291.A N ARG 223.A O no hydrogen 2.864 N/A GLN 291.A NE2 SER 292.A O no hydrogen 2.938 N/A TRP 293.A N ALA 225.A O no hydrogen 3.184 N/A TRP 293.A NE1 GLN 150.A OE1 no hydrogen 2.859 N/A ASP 299.A N ASN 296.A OD1 no hydrogen 2.952 N/A VAL 300.A N ASN 296.A O no hydrogen 2.943 N/A ALA 301.A N TRP 297.A O no hydrogen 2.849 N/A VAL 302.A N ASP 299.A O no hydrogen 3.108 N/A SER 303.A N ASP 299.A O no hydrogen 3.122 N/A SER 303.A OG ASP 299.A O no hydrogen 3.210 N/A SER 303.A OG VAL 300.A O no hydrogen 3.522 N/A LEU 304.A N VAL 300.A O no hydrogen 2.830 N/A ASP 307.A N SER 303.A O no hydrogen 3.015 N/A ILE 308.A N LEU 304.A O no hydrogen 2.846 N/A SER 309.A N SER 305.A O no hydrogen 2.979 N/A SER 309.A OG SER 305.A O no hydrogen 3.244 N/A ARG 310.A N ALA 306.A O no hydrogen 2.984 N/A ARG 310.A NH1 ASP 159.A OD1 no hydrogen 3.233 N/A ARG 310.A NH2 ASP 159.A OD1 no hydrogen 2.860 N/A TRP 311.A N ASP 307.A O no hydrogen 2.851 N/A TRP 311.A NE1 TYR 135.A OH no hydrogen 2.858 N/A HIS 312.A N ILE 308.A O no hydrogen 3.154 N/A HIS 312.A ND1 GLU 316.A OE2 no hydrogen 2.775 N/A LYS 313.A N SER 309.A O no hydrogen 3.100 N/A VAL 314.A N ARG 310.A O no hydrogen 2.828 N/A THR 315.A N TRP 311.A O no hydrogen 2.954 N/A THR 315.A OG1 TRP 311.A O no hydrogen 2.861 N/A GLU 316.A N HIS 312.A O no hydrogen 2.900 N/A SER 317.A OG LYS 313.A O no hydrogen 2.646 N/A