Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4r7o_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 2.A ND2 LYS 1.A O no hydrogen 3.018 N/A LEU 5.A N THR 263.A O no hydrogen 2.955 N/A ASN 6.A N ASP 33.A OD2 no hydrogen 2.813 N/A ASN 6.A ND2 PRO 270.A O no hydrogen 3.120 N/A ILE 7.A N MET 265.A O no hydrogen 3.120 N/A ALA 8.A N TYR 34.A O no hydrogen 2.996 N/A HIS 9.A N THR 267.A O no hydrogen 2.845 N/A HIS 9.A ND1 ASN 268.A OD1 no hydrogen 2.899 N/A ARG 10.A N GLU 36.A OE1 no hydrogen 2.982 N/A ARG 10.A NH1 GLU 18.A OE1 no hydrogen 3.033 N/A ARG 10.A NH1 GLU 18.A OE2 no hydrogen 3.321 N/A GLY 11.A N ALA 8.A O no hydrogen 3.077 N/A ALA 12.A N SER 23.A O no hydrogen 3.169 N/A SER 13.A OG HIS 9.A O no hydrogen 2.693 N/A GLY 14.A N ASN 268.A O no hydrogen 2.981 N/A HIS 15.A N ALA 12.A O no hydrogen 2.926 N/A HIS 15.A NE2 ASP 271.A OD1 no hydrogen 2.746 N/A ALA 16.A N ALA 12.A O no hydrogen 3.201 N/A HIS 19.A N ARG 10.A O no hydrogen 3.189 N/A HIS 19.A ND1 TYR 24.A OH no hydrogen 2.752 N/A HIS 19.A NE2 ASP 38.A OD2 no hydrogen 2.816 N/A THR 20.A OG1 PRO 17.A O no hydrogen 2.692 N/A ALA 22.A N GLN 97.A OE1 no hydrogen 3.334 N/A SER 23.A N THR 20.A O no hydrogen 3.110 N/A SER 23.A N THR 20.A OG1 no hydrogen 3.320 N/A SER 23.A OG ARG 10.A O no hydrogen 2.959 N/A TYR 24.A N THR 20.A O no hydrogen 3.021 N/A TYR 24.A OH HIS 19.A ND1 no hydrogen 2.752 N/A ASP 25.A N PHE 21.A O no hydrogen 2.777 N/A VAL 27.A N TYR 24.A O no hydrogen 3.289 N/A LYS 28.A NZ SER 112.A O no hydrogen 2.671 N/A MET 30.A N LEU 26.A O no hydrogen 2.941 N/A LYS 31.A N LYS 28.A O no hydrogen 3.165 N/A ALA 32.A N VAL 27.A O no hydrogen 3.109 N/A ASP 33.A N ASN 6.A O no hydrogen 2.703 N/A TYR 34.A N ASN 6.A O no hydrogen 3.217 N/A LEU 35.A N LYS 114.A O no hydrogen 2.882 N/A GLU 36.A N ALA 8.A O no hydrogen 3.084 N/A LEU 37.A N TYR 116.A O no hydrogen 2.899 N/A GLN 40.A N ILE 48.A O no hydrogen 2.902 N/A GLN 40.A NE2 MET 50.A O no hydrogen 2.986 N/A THR 42.A N GLN 46.A O no hydrogen 2.869 N/A THR 42.A OG1 ASP 44.A OD1 no hydrogen 2.750 N/A THR 42.A OG1 GLN 46.A O no hydrogen 3.360 N/A LYS 43.A N LYS 68.A O no hydrogen 2.736 N/A ASP 44.A N ASP 44.A OD1 no hydrogen 2.529 N/A GLY 45.A N THR 42.A O no hydrogen 2.886 N/A GLN 46.A N THR 42.A OG1 no hydrogen 3.106 N/A ILE 48.A N GLN 40.A O no hydrogen 3.008 N/A ALA 49.A N PRO 100.A O no hydrogen 2.900 N/A MET 50.A N ASP 38.A O no hydrogen 3.107 N/A HIS 51.A ND1 ASP 52.A OD1 no hydrogen 3.063 N/A THR 53.A OG1 GLU 64.A OE1 no hydrogen 3.181 N/A VAL 55.A N GLY 63.A O no hydrogen 2.935 N/A ARG 57.A NE ASP 52.A OD2 no hydrogen 2.844 N/A ARG 57.A NH1 GLU 18.A OE1 no hydrogen 3.204 N/A ARG 57.A NH2 GLU 18.A OE2 no hydrogen 2.957 N/A ARG 57.A NH2 ASP 52.A OD2 no hydrogen 3.510 N/A THR 59.A OG1 VAL 55.A O no hydrogen 2.817 N/A GLY 61.A N THR 59.A OG1 no hydrogen 2.885 N/A THR 62.A OG1 ASP 56.A OD2 no hydrogen 2.907 N/A GLY 63.A N ASP 56.A OD1 no hydrogen 3.171 N/A VAL 65.A N THR 53.A O no hydrogen 2.778 N/A ARG 66.A NH2 VAL 124.A O no hydrogen 3.084 N/A ASP 67.A N GLU 64.A O no hydrogen 3.355 N/A LYS 68.A N VAL 65.A O no hydrogen 2.777 N/A LYS 68.A NZ THR 62.A O no hydrogen 2.532 N/A THR 69.A N GLU 72.A OE2 no hydrogen 3.015 N/A THR 69.A OG1 GLU 72.A OE2 no hydrogen 3.014 N/A LEU 70.A N ASP 44.A OD1 no hydrogen 2.938 N/A GLU 72.A N THR 69.A OG1 no hydrogen 3.355 N/A ILE 73.A N THR 69.A O no hydrogen 3.160 N/A LYS 74.A N LEU 70.A O no hydrogen 2.974 N/A LYS 74.A NZ VAL 99.A O no hydrogen 2.679 N/A LYS 74.A NZ GLU 104.A OE1 no hydrogen 2.827 N/A LYS 74.A NZ GLU 104.A OE2 no hydrogen 3.229 N/A SER 75.A N GLU 72.A O no hydrogen 3.301 N/A SER 75.A OG GLU 72.A O no hydrogen 2.909 N/A LEU 76.A N ILE 73.A O no hydrogen 3.119 N/A ASP 77.A N ASN 60.A OD1 no hydrogen 2.905 N/A ALA 78.A N GLN 97.A O no hydrogen 2.786 N/A GLY 79.A N ASP 77.A OD1 no hydrogen 2.925 N/A SER 80.A N ASP 77.A OD1 no hydrogen 3.148 N/A SER 80.A OG ASP 77.A OD2 no hydrogen 2.592 N/A PHE 82.A N GLY 79.A O no hydrogen 3.314 N/A ASN 83.A ND2 LYS 91.A O no hydrogen 2.814 N/A LYS 84.A N SER 80.A O no hydrogen 3.247 N/A ALA 85.A N TRP 81.A O no hydrogen 2.865 N/A TYR 86.A N PHE 82.A O no hydrogen 2.826 N/A LYS 89.A N TYR 86.A O no hydrogen 2.879 N/A LYS 89.A NZ GLY 14.A O no hydrogen 2.838 N/A LYS 89.A NZ TYR 269.A OH no hydrogen 3.045 N/A ALA 90.A N PRO 87.A O no hydrogen 3.400 N/A LYS 91.A N ASN 83.A OD1 no hydrogen 3.110 N/A TYR 94.A N LYS 91.A O no hydrogen 2.990 N/A TYR 94.A OH HIS 15.A O no hydrogen 2.748 N/A VAL 95.A N GLN 92.A O no hydrogen 2.972 N/A GLY 96.A N ASP 77.A OD1 no hydrogen 3.042 N/A GLN 97.A N TYR 94.A O no hydrogen 3.413 N/A GLN 97.A NE2 GLU 93.A O no hydrogen 3.183 N/A LYS 98.A NZ LYS 74.A O no hydrogen 3.216 N/A THR 101.A N GLU 104.A OE1 no hydrogen 2.967 N/A LEU 102.A N LEU 47.A O no hydrogen 2.978 N/A GLU 104.A N THR 101.A OG1 no hydrogen 3.037 N/A ILE 105.A N THR 101.A O no hydrogen 3.201 N/A PHE 106.A N LEU 102.A O no hydrogen 3.041 N/A GLN 107.A N GLU 103.A O no hydrogen 2.788 N/A LYS 108.A N GLU 104.A O no hydrogen 3.014 N/A LYS 108.A N ILE 105.A O no hydrogen 3.176 N/A LYS 108.A NZ ASP 25.A OD1 no hydrogen 3.086 N/A LYS 108.A NZ ASP 25.A OD2 no hydrogen 3.278 N/A TYR 109.A N ILE 105.A O no hydrogen 3.187 N/A TYR 109.A OH ASP 25.A OD1 no hydrogen 2.545 N/A GLY 110.A N PHE 106.A O no hydrogen 2.866 N/A ARG 111.A NE ASN 140.A O no hydrogen 3.275 N/A ARG 111.A NH2 ASN 140.A O no hydrogen 2.993 N/A SER 112.A N TYR 109.A O no hydrogen 2.935 N/A SER 112.A OG TYR 109.A O no hydrogen 2.712 N/A LYS 114.A NZ SER 149.A O no hydrogen 3.440 N/A TYR 115.A N ARG 150.A O no hydrogen 2.818 N/A TYR 115.A OH GLY 110.A O no hydrogen 2.585 N/A TYR 116.A N LEU 35.A O no hydrogen 3.060 N/A TYR 116.A OH HIS 244.A ND1 no hydrogen 2.694 N/A ILE 117.A N MET 152.A O no hydrogen 2.905 N/A GLU 118.A N LEU 37.A O no hydrogen 2.855 N/A THR 119.A N GLN 154.A O no hydrogen 3.019 N/A THR 119.A OG1 SER 155.A OG no hydrogen 3.126 N/A THR 119.A OG1 SER 160.A OG no hydrogen 2.542 N/A VAL 124.A N SER 121.A O no hydrogen 2.967 N/A TYR 125.A OH GLN 40.A OE1 no hydrogen 2.492 N/A MET 128.A N TYR 125.A O no hydrogen 3.021 N/A GLU 129.A N GLU 129.A OE1 no hydrogen 2.953 N/A GLU 130.A N GLU 130.A OE1 no hydrogen 2.658 N/A LYS 131.A N GLY 127.A O no hydrogen 3.148 N/A LEU 132.A N MET 128.A O no hydrogen 2.825 N/A LEU 133.A N GLU 129.A O no hydrogen 2.863 N/A ALA 134.A N GLU 130.A O no hydrogen 3.020 N/A LEU 135.A N LYS 131.A O no hydrogen 3.024 N/A LEU 136.A N LEU 132.A O no hydrogen 3.034 N/A GLU 137.A N LEU 133.A O no hydrogen 3.180 N/A LYS 138.A N ALA 134.A O no hydrogen 2.845 N/A LYS 138.A NZ GLU 103.A OE2 no hydrogen 2.491 N/A TYR 139.A N LEU 135.A O no hydrogen 3.309 N/A TYR 139.A OH GLU 103.A OE2 no hydrogen 2.862 N/A ASN 140.A N GLU 137.A O no hydrogen 3.156 N/A LEU 141.A N LEU 136.A O no hydrogen 2.962 N/A SER 149.A OG VAL 151.A O no hydrogen 3.329 N/A ARG 150.A N LEU 141.A O no hydrogen 3.424 N/A MET 152.A N TYR 115.A O no hydrogen 2.746 N/A ILE 153.A N PRO 172.A O no hydrogen 2.984 N/A GLN 154.A N ILE 117.A O no hydrogen 2.881 N/A GLN 154.A NE2 GLU 36.A OE2 no hydrogen 2.920 N/A SER 155.A N VAL 174.A O no hydrogen 3.219 N/A SER 155.A OG THR 119.A O no hydrogen 2.715 N/A SER 155.A OG THR 119.A OG1 no hydrogen 3.126 N/A SER 157.A N SER 155.A OG no hydrogen 3.233 N/A SER 160.A N SER 157.A OG no hydrogen 3.086 N/A SER 160.A OG THR 119.A OG1 no hydrogen 2.542 N/A SER 160.A OG LYS 120.A O no hydrogen 3.364 N/A SER 160.A OG GLU 129.A OE2 no hydrogen 2.878 N/A LEU 161.A N SER 157.A O no hydrogen 3.301 N/A LYS 162.A N LYS 158.A O no hydrogen 2.948 N/A LYS 163.A N ASP 159.A O no hydrogen 3.021 N/A ILE 164.A N SER 160.A O no hydrogen 3.160 N/A HIS 165.A N LEU 161.A O no hydrogen 2.789 N/A SER 166.A N LYS 162.A O no hydrogen 3.099 N/A SER 166.A N LYS 163.A O no hydrogen 3.038 N/A ILE 167.A N LYS 163.A O no hydrogen 3.128 N/A ASN 168.A N ILE 164.A O no hydrogen 2.823 N/A LYS 169.A NZ HIS 165.A O no hydrogen 2.698 N/A ASN 170.A N ASN 168.A OD1 no hydrogen 2.916 N/A VAL 174.A N ILE 153.A O no hydrogen 2.773 N/A GLN 175.A N GLY 214.A O no hydrogen 2.937 N/A GLN 175.A NE2 PHE 156.A O no hydrogen 3.338 N/A GLN 175.A NE2 LEU 176.A O no hydrogen 2.909 N/A LEU 176.A N SER 155.A O no hydrogen 2.938 N/A LEU 177.A N GLY 216.A O no hydrogen 2.980 N/A TRP 178.A N GLU 189.A OE2 no hydrogen 2.960 N/A TYR 179.A N ASN 218.A OD1 no hydrogen 2.822 N/A TYR 179.A OH THR 194.A OG1 no hydrogen 2.738 N/A TYR 179.A OH TYR 232.A OH no hydrogen 2.704 N/A TYR 180.A N VAL 188.A O no hydrogen 3.145 N/A ASN 182.A N GLU 186.A O no hydrogen 2.721 N/A ASN 182.A ND2 GLU 186.A OE1 no hydrogen 3.108 N/A ASN 184.A N ASN 182.A OD1 no hydrogen 2.843 N/A ASN 184.A ND2 GLU 186.A OE1 no hydrogen 3.412 N/A ASN 185.A N ASN 182.A O no hydrogen 2.830 N/A GLU 186.A N ASN 182.A OD1 no hydrogen 2.971 N/A VAL 188.A N TYR 180.A O no hydrogen 2.965 N/A TRP 190.A N TRP 178.A O no hydrogen 2.823 N/A SER 191.A N GLU 189.A OE1 no hydrogen 2.666 N/A SER 191.A OG PHE 156.A O no hydrogen 3.508 N/A GLY 192.A N GLU 189.A O no hydrogen 2.974 N/A ILE 193.A N GLU 189.A OE1 no hydrogen 3.080 N/A THR 194.A OG1 TYR 179.A OH no hydrogen 2.738 N/A THR 194.A OG1 HIS 195.A O no hydrogen 2.644 N/A HIS 195.A N ASP 204.A OD2 no hydrogen 2.932 N/A HIS 195.A ND1 ASP 204.A OD1 no hydrogen 3.076 N/A HIS 195.A ND1 ASP 204.A OD2 no hydrogen 2.694 N/A ARG 199.A N GLU 196.A O no hydrogen 2.881 N/A ARG 199.A NH1 GLU 196.A OE2 no hydrogen 2.952 N/A THR 201.A N ASP 204.A OD2 no hydrogen 3.171 N/A ASP 204.A N THR 201.A OG1 no hydrogen 3.081 N/A PHE 205.A N THR 201.A O no hydrogen 3.481 N/A GLN 206.A N ASN 202.A O no hydrogen 2.778 N/A GLN 206.A NE2 ASN 239.A OD1 no hydrogen 2.743 N/A GLU 207.A N ASP 203.A O no hydrogen 2.986 N/A LYS 209.A N PHE 205.A O no hydrogen 2.894 N/A LYS 210.A N GLU 207.A O no hydrogen 3.341 N/A LYS 210.A NZ GLU 207.A OE1 no hydrogen 3.383 N/A LYS 210.A NZ GLU 207.A OE2 no hydrogen 2.928 N/A TYR 211.A N ILE 208.A O no hydrogen 3.101 N/A TYR 211.A OH GLN 175.A OE1 no hydrogen 2.730 N/A ALA 212.A N ILE 208.A O no hydrogen 2.901 N/A VAL 213.A N LEU 173.A O no hydrogen 2.868 N/A ILE 215.A N LEU 242.A O no hydrogen 2.842 N/A GLY 216.A N GLN 175.A O no hydrogen 2.959 N/A ASN 218.A ND2 TYR 179.A O no hydrogen 3.034 N/A ASN 218.A ND2 ARG 220.A O no hydrogen 2.799 N/A LEU 219.A N TYR 246.A O no hydrogen 3.088 N/A ARG 220.A NE ASP 253.A OD2 no hydrogen 2.783 N/A ARG 220.A NH1 ASP 253.A OD1 no hydrogen 2.773 N/A ARG 220.A NH1 ASP 253.A OD2 no hydrogen 3.310 N/A ARG 220.A NH2 GLY 224.A O no hydrogen 2.860 N/A ASN 221.A N ASP 225.A O no hydrogen 2.774 N/A GLY 224.A N ASN 221.A O no hydrogen 2.978 N/A ASP 225.A N ASN 221.A OD1 no hydrogen 2.834 N/A ILE 227.A N LEU 219.A O no hydrogen 3.011 N/A TYR 232.A N ASN 229.A OD1 no hydrogen 3.305 N/A TYR 232.A OH TYR 179.A OH no hydrogen 2.704 N/A MET 233.A N ASN 229.A O no hydrogen 3.450 N/A LYS 234.A N GLU 230.A O no hydrogen 2.964 N/A MET 235.A N SER 231.A O no hydrogen 3.075 N/A ALA 236.A N TYR 232.A O no hydrogen 3.080 N/A ARG 237.A N MET 233.A O no hydrogen 2.982 N/A ARG 237.A NE LEU 241.A O no hydrogen 3.113 N/A ARG 237.A NH1 ASN 2.A OD1 no hydrogen 3.365 N/A ARG 237.A NH1 LEU 241.A O no hydrogen 3.311 N/A ARG 237.A NH2 ASN 2.A OD1 no hydrogen 3.101 N/A GLN 238.A N LYS 234.A O no hydrogen 3.018 N/A GLN 238.A NE2 ASN 202.A OD1 no hydrogen 3.490 N/A ASN 239.A N MET 235.A O no hydrogen 3.273 N/A ASN 239.A N ALA 236.A O no hydrogen 3.170 N/A ASN 239.A ND2 ASN 202.A OD1 no hydrogen 2.987 N/A ASN 239.A ND2 MET 235.A O no hydrogen 2.735 N/A GLY 240.A N ARG 237.A O no hydrogen 2.938 N/A LEU 241.A N ALA 236.A O no hydrogen 3.125 N/A LEU 242.A N VAL 213.A O no hydrogen 2.981 N/A ILE 243.A N THR 263.A OG1 no hydrogen 2.946 N/A HIS 244.A N ILE 215.A O no hydrogen 2.866 N/A HIS 244.A ND1 TYR 116.A OH no hydrogen 2.694 N/A TYR 246.A N PRO 217.A O no hydrogen 3.193 N/A TYR 246.A OH LEU 177.A O no hydrogen 2.679 N/A ILE 248.A N PHE 266.A O no hydrogen 2.776 N/A MET 254.A N GLU 250.A O no hydrogen 2.873 N/A ARG 255.A N LYS 251.A O no hydrogen 2.796 N/A ARG 255.A NE GLU 279.A OE1 no hydrogen 3.147 N/A ARG 255.A NH2 GLU 279.A OE2 no hydrogen 3.066 N/A LEU 256.A N PRO 252.A O no hydrogen 3.045 N/A LEU 257.A N ASP 253.A O no hydrogen 3.203 N/A MET 258.A N MET 254.A O no hydrogen 3.171 N/A LYS 259.A N ARG 255.A O no hydrogen 3.241 N/A TRP 260.A N LEU 256.A O no hydrogen 2.890 N/A GLY 261.A N LEU 257.A O no hydrogen 2.961 N/A GLY 261.A N MET 258.A O no hydrogen 3.042 N/A ALA 262.A N LEU 257.A O no hydrogen 2.984 N/A THR 263.A N ILE 243.A O no hydrogen 3.015 N/A THR 263.A OG1 ILE 243.A O no hydrogen 3.354 N/A GLY 264.A N ILE 243.A O no hydrogen 3.250 N/A MET 265.A N LEU 5.A O no hydrogen 3.092 N/A PHE 266.A N PRO 245.A O no hydrogen 2.843 N/A THR 267.A N ILE 7.A O no hydrogen 3.006 N/A THR 267.A OG1 ILE 248.A O no hydrogen 2.791 N/A ASN 268.A N ASN 249.A OD1 no hydrogen 2.849 N/A TYR 269.A N THR 267.A OG1 no hydrogen 2.915 N/A ASP 271.A N ASP 271.A OD1 no hydrogen 2.596 N/A ARG 272.A NH1 ASN 249.A O no hydrogen 2.859 N/A LEU 273.A N TYR 269.A O no hydrogen 3.288 N/A HIS 274.A N PRO 270.A O no hydrogen 3.090 N/A THR 275.A N ASP 271.A O no hydrogen 3.041 N/A THR 275.A OG1 ASP 271.A O no hydrogen 3.183 N/A VAL 276.A N ARG 272.A O no hydrogen 3.007 N/A LEU 277.A N LEU 273.A O no hydrogen 2.770 N/A LYS 278.A N HIS 274.A O no hydrogen 3.074 N/A LYS 278.A N THR 275.A O no hydrogen 3.114 N/A GLU 279.A N VAL 276.A O no hydrogen 3.305 N/A