Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4rae_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 4.A N ASP 7.A OD2 no hydrogen 3.167 N/A ASP 7.A N THR 4.A O no hydrogen 2.691 N/A LEU 10.A N LEU 8.A O no hydrogen 2.759 N/A LEU 14.A N ARG 11.A O no hydrogen 2.895 N/A ARG 15.A N ARG 11.A O no hydrogen 3.097 N/A GLN 24.A N GLY 21.A O no hydrogen 2.775 N/A LEU 25.A N ALA 22.A O no hydrogen 2.905 N/A VAL 29.A N GLY 328.A O no hydrogen 3.350 N/A LEU 31.A N LEU 330.A O no hydrogen 2.741 N/A THR 33.A OG1 GLU 35.A OE1 no hydrogen 2.685 N/A THR 33.A OG1 GLU 35.A OE2 no hydrogen 3.454 N/A GLU 35.A N GLU 35.A OE1 no hydrogen 2.581 N/A ASN 36.A ND2 ALA 228.A O no hydrogen 3.596 N/A HIS 38.A N ASN 36.A OD1 no hydrogen 2.754 N/A THR 41.A OG1 ASP 275.A OD2 no hydrogen 3.121 N/A VAL 45.A N THR 41.A O no hydrogen 2.659 N/A ASP 46.A N ARG 42.A O no hydrogen 2.573 N/A ASP 47.A N ALA 43.A O no hydrogen 3.342 N/A VAL 48.A N LEU 44.A O no hydrogen 2.816 N/A VAL 49.A N VAL 45.A O no hydrogen 2.757 N/A ARG 50.A N ASP 46.A O no hydrogen 2.954 N/A SER 51.A N ASP 47.A O no hydrogen 2.787 N/A SER 51.A OG ASP 47.A O no hydrogen 3.201 N/A SER 51.A OG ASP 47.A OD1 no hydrogen 3.285 N/A VAL 52.A N VAL 48.A O no hydrogen 2.830 N/A ARG 53.A N VAL 49.A O no hydrogen 2.634 N/A GLU 54.A N ARG 50.A O no hydrogen 2.911 N/A ALA 55.A N SER 51.A O no hydrogen 3.046 N/A ALA 56.A N ARG 53.A O no hydrogen 3.187 N/A VAL 68.A N ASP 64.A OD2 no hydrogen 2.529 N/A ALA 69.A N ASP 64.A OD2 no hydrogen 3.090 N/A ARG 71.A N ALA 67.A O no hydrogen 2.872 N/A ARG 71.A NE ILE 91.A O no hydrogen 2.724 N/A ARG 71.A NH1 ASP 66.A O no hydrogen 2.752 N/A ARG 71.A NH2 VAL 88.A O no hydrogen 2.935 N/A ARG 71.A NH2 ILE 91.A O no hydrogen 3.377 N/A ALA 72.A N VAL 68.A O no hydrogen 2.860 N/A ASP 73.A N ALA 69.A O no hydrogen 2.953 N/A LEU 74.A N LEU 70.A O no hydrogen 2.809 N/A ALA 75.A N ARG 71.A O no hydrogen 2.996 N/A GLY 76.A N ALA 72.A O no hydrogen 2.892 N/A TYR 77.A N ASP 73.A O no hydrogen 2.738 N/A TYR 77.A OH GLU 201.A OE1 no hydrogen 2.758 N/A LEU 78.A N LEU 74.A O no hydrogen 2.791 N/A LEU 78.A N ALA 75.A O no hydrogen 2.870 N/A THR 79.A N ALA 75.A O no hydrogen 2.791 N/A THR 79.A OG1 ALA 75.A O no hydrogen 2.736 N/A THR 79.A OG1 LEU 86.A O no hydrogen 3.138 N/A ALA 80.A N GLY 76.A O no hydrogen 3.336 N/A GLN 81.A N TYR 77.A O no hydrogen 3.124 N/A THR 82.A N LEU 78.A O no hydrogen 2.729 N/A THR 82.A OG1 LEU 78.A O no hydrogen 2.975 N/A GLY 83.A N THR 79.A O no hydrogen 2.508 N/A GLU 89.A N GLU 89.A OE2 no hydrogen 2.896 N/A ASN 90.A N GLY 87.A O no hydrogen 2.872 N/A ASN 90.A ND2 GLY 87.A O no hydrogen 3.389 N/A ILE 91.A N VAL 88.A O no hydrogen 3.434 N/A TRP 92.A N LEU 239.A O no hydrogen 3.207 N/A ALA 94.A N GLY 237.A O no hydrogen 2.919 N/A ASN 95.A N GLU 99.A OE2 no hydrogen 2.922 N/A ASN 95.A ND2 GLU 99.A OE1 no hydrogen 2.648 N/A ASN 95.A ND2 HIS 257.A O no hydrogen 3.030 N/A ILE 100.A N GLY 96.A O no hydrogen 3.318 N/A LEU 101.A N SER 97.A O no hydrogen 3.195 N/A GLN 102.A N ASN 98.A O no hydrogen 2.749 N/A GLN 103.A N GLU 99.A O no hydrogen 2.748 N/A LEU 104.A N ILE 100.A O no hydrogen 2.864 N/A LEU 105.A N LEU 101.A O no hydrogen 3.273 N/A LEU 105.A N GLN 102.A O no hydrogen 2.912 N/A GLN 106.A N GLN 102.A O no hydrogen 2.820 N/A ALA 107.A N GLN 103.A O no hydrogen 2.917 N/A PHE 108.A N LEU 104.A O no hydrogen 2.918 N/A GLY 109.A N LEU 105.A O no hydrogen 2.810 N/A ARG 113.A N GLY 110.A O no hydrogen 3.229 N/A ARG 113.A NH1 PHE 108.A O no hydrogen 3.203 N/A SER 114.A N ASP 162.A OD1 no hydrogen 2.858 N/A ALA 115.A N HIS 133.A O no hydrogen 2.893 N/A ILE 116.A N VAL 163.A O no hydrogen 2.887 N/A GLY 117.A N GLU 135.A O no hydrogen 2.859 N/A VAL 119.A N ILE 137.A O no hydrogen 2.879 N/A THR 134.A OG1 THR 132.A O no hydrogen 3.065 N/A GLU 135.A N ALA 115.A O no hydrogen 2.898 N/A ILE 137.A N GLY 117.A O no hydrogen 3.048 N/A ALA 139.A N VAL 119.A O no hydrogen 2.886 N/A ARG 141.A NH1 ASP 144.A OD2 no hydrogen 2.603 N/A PHE 145.A N ARG 141.A O no hydrogen 2.668 N/A GLY 146.A N ASP 144.A OD2 no hydrogen 3.374 N/A ASP 148.A N ALA 139.A O no hydrogen 2.489 N/A VAL 149.A N LEU 147.A O no hydrogen 2.922 N/A ASP 150.A N ASP 148.A OD1 no hydrogen 3.305 N/A VAL 151.A N ASP 148.A OD1 no hydrogen 3.324 N/A ALA 152.A N ASP 148.A O no hydrogen 3.020 N/A VAL 153.A N VAL 149.A O no hydrogen 2.816 N/A ALA 154.A N ASP 150.A O no hydrogen 3.220 N/A ALA 155.A N VAL 151.A O no hydrogen 2.938 N/A VAL 156.A N ALA 152.A O no hydrogen 2.757 N/A VAL 157.A N VAL 153.A O no hydrogen 2.921 N/A ASP 158.A N ALA 154.A O no hydrogen 3.297 N/A ARG 159.A N ALA 155.A O no hydrogen 2.763 N/A LYS 160.A N VAL 156.A O no hydrogen 3.111 N/A LYS 160.A NZ VAL 157.A O no hydrogen 3.461 N/A ASP 162.A N SER 114.A O no hydrogen 2.821 N/A VAL 163.A N SER 114.A O no hydrogen 3.195 N/A VAL 164.A N ILE 192.A O no hydrogen 2.815 N/A PHE 165.A N ILE 116.A O no hydrogen 3.074 N/A ILE 166.A N ILE 194.A O no hydrogen 2.907 N/A SER 168.A N ASP 196.A O no hydrogen 3.032 N/A ASN 170.A N GLN 175.A O no hydrogen 3.052 N/A ASN 171.A N SER 121.A O no hydrogen 3.174 N/A SER 173.A OG PHE 145.A O no hydrogen 3.245 N/A SER 173.A OG ASN 170.A OD1 no hydrogen 3.147 N/A GLN 175.A NE2 ASP 144.A OD1 no hydrogen 3.526 N/A SER 176.A N ASP 305.A OD2 no hydrogen 3.455 N/A SER 176.A OG SER 203.A OG no hydrogen 3.000 N/A VAL 177.A N SER 168.A OG no hydrogen 3.081 N/A ASP 181.A N SER 178.A OG no hydrogen 3.212 N/A LEU 182.A N SER 178.A O no hydrogen 3.018 N/A CYS 183.A N LEU 179.A O no hydrogen 3.244 N/A CYS 183.A SG LEU 179.A O no hydrogen 3.293 N/A LYS 184.A N PRO 180.A O no hydrogen 3.128 N/A LEU 185.A N ASP 181.A O no hydrogen 3.159 N/A LEU 185.A N LEU 182.A O no hydrogen 2.982 N/A LEU 186.A N LEU 182.A O no hydrogen 2.771 N/A ASP 187.A N CYS 183.A O no hydrogen 2.900 N/A VAL 188.A N LEU 185.A O no hydrogen 2.872 N/A ALA 189.A N LEU 186.A O no hydrogen 3.311 N/A ILE 192.A N ASP 162.A O no hydrogen 2.916 N/A ALA 193.A N LYS 218.A O no hydrogen 2.861 N/A ILE 194.A N VAL 164.A O no hydrogen 2.931 N/A VAL 195.A N VAL 220.A O no hydrogen 2.831 N/A ASP 196.A N ILE 166.A O no hydrogen 2.780 N/A GLU 197.A N THR 222.A O no hydrogen 2.869 N/A ALA 198.A N ASP 196.A OD1 no hydrogen 2.900 N/A GLY 200.A N GLU 197.A O no hydrogen 3.029 N/A PHE 202.A N TYR 199.A O no hydrogen 2.982 N/A SER 203.A N GLY 200.A O no hydrogen 2.970 N/A SER 203.A OG SER 176.A OG no hydrogen 3.000 N/A SER 203.A OG GLN 205.A O no hydrogen 3.250 N/A SER 207.A OG GLU 197.A OE1 no hydrogen 3.229 N/A SER 207.A OG GLU 197.A OE2 no hydrogen 3.456 N/A ALA 208.A N GLU 197.A OE2 no hydrogen 2.797 N/A VAL 209.A N SER 207.A OG no hydrogen 2.844 N/A SER 210.A N SER 207.A O no hydrogen 3.380 N/A SER 210.A OG SER 207.A O no hydrogen 2.800 N/A LEU 211.A N ALA 208.A O no hydrogen 2.852 N/A GLU 214.A N LEU 211.A O no hydrogen 2.812 N/A TYR 215.A N VAL 212.A O no hydrogen 2.986 N/A TYR 215.A OH ASP 187.A OD2 no hydrogen 2.625 N/A LYS 218.A N TYR 215.A O no hydrogen 2.985 N/A LYS 218.A NZ LEU 186.A O no hydrogen 2.467 N/A LYS 218.A NZ ALA 189.A O no hydrogen 2.897 N/A LEU 219.A N TYR 215.A O no hydrogen 3.046 N/A VAL 220.A N ALA 193.A O no hydrogen 2.929 N/A VAL 221.A N ILE 240.A O no hydrogen 3.186 N/A THR 222.A N VAL 195.A O no hydrogen 2.872 N/A THR 222.A OG1 ASP 196.A OD1 no hydrogen 3.541 N/A ARG 223.A N TYR 238.A O no hydrogen 3.024 N/A ARG 223.A NH2 GLU 201.A OE1 no hydrogen 3.567 N/A THR 224.A OG1 SER 226.A OG no hydrogen 2.893 N/A THR 224.A OG1 LEU 236.A O no hydrogen 3.400 N/A MET 225.A N LEU 236.A O no hydrogen 3.219 N/A SER 226.A N THR 224.A OG1 no hydrogen 3.249 N/A SER 226.A OG THR 224.A OG1 no hydrogen 2.893 N/A PHE 229.A N MET 225.A O no hydrogen 2.900 N/A GLY 234.A N PHE 231.A O no hydrogen 2.961 N/A GLY 237.A N ALA 94.A O no hydrogen 2.942 N/A TYR 238.A N ARG 223.A O no hydrogen 3.371 N/A LEU 239.A N TRP 92.A O no hydrogen 2.952 N/A ILE 240.A N VAL 221.A O no hydrogen 2.802 N/A ALA 241.A N ASN 90.A O no hydrogen 2.922 N/A VAL 245.A N THR 242.A O no hydrogen 2.786 N/A ASP 247.A N PRO 243.A O no hydrogen 2.907 N/A ALA 248.A N ALA 244.A O no hydrogen 3.174 N/A MET 249.A N VAL 245.A O no hydrogen 2.917 N/A LEU 250.A N ILE 246.A O no hydrogen 2.997 N/A LEU 251.A N ASP 247.A O no hydrogen 3.221 N/A VAL 252.A N ALA 248.A O no hydrogen 3.184 N/A ARG 253.A N MET 249.A O no hydrogen 2.978 N/A ARG 253.A NH1 LEU 250.A O no hydrogen 3.238 N/A HIS 257.A NE2 ALA 93.A O no hydrogen 3.371 N/A SER 259.A OG THR 262.A OG1 no hydrogen 3.016 N/A SER 260.A OG LEU 59.A O no hydrogen 3.038 N/A THR 262.A N SER 259.A OG no hydrogen 2.969 N/A THR 262.A OG1 SER 259.A O no hydrogen 3.170 N/A THR 262.A OG1 SER 259.A OG no hydrogen 3.016 N/A GLN 263.A N SER 259.A O no hydrogen 2.711 N/A ALA 264.A N SER 260.A O no hydrogen 2.859 N/A ALA 265.A N VAL 261.A O no hydrogen 2.978 N/A ALA 266.A N THR 262.A O no hydrogen 3.226 N/A ARG 267.A N GLN 263.A O no hydrogen 3.141 N/A ARG 267.A NE ASP 73.A OD2 no hydrogen 3.171 N/A ALA 268.A N ALA 264.A O no hydrogen 3.132 N/A ALA 269.A N ALA 265.A O no hydrogen 3.242 N/A LEU 270.A N ALA 266.A O no hydrogen 2.984 N/A ARG 271.A N ARG 267.A O no hydrogen 3.085 N/A ARG 271.A N ALA 268.A O no hydrogen 2.664 N/A ARG 271.A NH1 ASP 47.A OD1 no hydrogen 2.840 N/A ARG 271.A NH2 SER 51.A OG no hydrogen 2.886 N/A HIS 272.A N ALA 269.A O no hydrogen 2.964 N/A SER 273.A N LEU 270.A O no hydrogen 3.405 N/A SER 273.A OG LEU 270.A O no hydrogen 3.299 N/A SER 273.A OG ASP 274.A OD1 no hydrogen 3.562 N/A THR 276.A N HIS 272.A O no hydrogen 3.395 N/A THR 276.A OG1 SER 273.A O no hydrogen 3.411 N/A LEU 277.A N SER 273.A O no hydrogen 2.724 N/A SER 278.A N ASP 274.A O no hydrogen 3.030 N/A SER 278.A OG ASP 275.A O no hydrogen 2.847 N/A SER 279.A N ASP 275.A O no hydrogen 3.223 N/A SER 279.A OG THR 276.A O no hydrogen 3.078 N/A VAL 280.A N THR 276.A O no hydrogen 2.884 N/A ALA 281.A N LEU 277.A O no hydrogen 2.773 N/A ALA 282.A N SER 278.A O no hydrogen 3.198 N/A LEU 283.A N SER 279.A O no hydrogen 3.168 N/A ILE 284.A N VAL 280.A O no hydrogen 2.952 N/A ALA 285.A N ALA 281.A O no hydrogen 2.867 N/A GLU 286.A N ALA 282.A O no hydrogen 2.813 N/A ARG 287.A N LEU 283.A O no hydrogen 2.698 N/A GLU 288.A N ILE 284.A O no hydrogen 2.780 N/A ARG 289.A N ALA 285.A O no hydrogen 3.057 N/A ARG 289.A NE GLU 286.A OE2 no hydrogen 2.916 N/A ARG 289.A NH1 ASP 351.A OD1 no hydrogen 2.875 N/A ARG 289.A NH2 GLU 286.A OE1 no hydrogen 2.599 N/A ARG 289.A NH2 GLU 286.A OE2 no hydrogen 3.199 N/A ARG 289.A NH2 ASP 351.A OD1 no hydrogen 3.152 N/A VAL 290.A N GLU 286.A O no hydrogen 2.925 N/A THR 291.A N ARG 287.A O no hydrogen 2.830 N/A THR 291.A OG1 ARG 287.A O no hydrogen 2.871 N/A THR 292.A N GLU 288.A O no hydrogen 2.790 N/A THR 292.A OG1 GLU 288.A O no hydrogen 2.981 N/A THR 292.A OG1 ARG 289.A O no hydrogen 2.997 N/A SER 293.A N ARG 289.A O no hydrogen 2.747 N/A LEU 294.A N VAL 290.A O no hydrogen 2.666 N/A ASN 295.A N THR 291.A O no hydrogen 2.969 N/A ASN 295.A ND2 PHE 299.A O no hydrogen 2.778 N/A ASP 296.A N THR 292.A O no hydrogen 2.882 N/A MET 297.A N SER 293.A O no hydrogen 3.165 N/A GLY 298.A N ASN 295.A O no hydrogen 2.517 N/A PHE 299.A N LEU 294.A O no hydrogen 2.974 N/A ARG 300.A NH2 ASN 143.A O no hydrogen 3.285 N/A ILE 302.A N LEU 310.A O no hydrogen 2.911 N/A SER 304.A OG PHE 308.A O no hydrogen 2.727 N/A ASP 305.A N GLY 174.A O no hydrogen 2.522 N/A ALA 306.A N SER 304.A OG no hydrogen 3.094 N/A VAL 309.A N ALA 342.A O no hydrogen 2.896 N/A PHE 311.A N LEU 340.A O no hydrogen 2.964 N/A GLY 312.A N ARG 300.A O no hydrogen 2.787 N/A PHE 314.A N GLY 338.A O no hydrogen 2.833 N/A ALA 315.A N ASP 363.A O no hydrogen 3.476 N/A ALA 319.A N ASP 316.A O no hydrogen 3.026 N/A ALA 319.A N ASP 316.A OD2 no hydrogen 3.259 N/A ALA 320.A N ASP 316.A O no hydrogen 3.090 N/A ALA 320.A N ALA 317.A O no hydrogen 3.046 N/A TRP 321.A N ALA 317.A O no hydrogen 2.860 N/A TRP 321.A NE1 ILE 331.A O no hydrogen 2.442 N/A ARG 322.A N PRO 318.A O no hydrogen 3.208 N/A ARG 323.A N ALA 319.A O no hydrogen 3.200 N/A TYR 324.A N ALA 320.A O no hydrogen 2.993 N/A TYR 324.A OH SER 357.A OG no hydrogen 2.652 N/A LEU 325.A N TRP 321.A O no hydrogen 3.064 N/A GLU 326.A N ARG 322.A O no hydrogen 2.982 N/A ALA 327.A N ARG 323.A O no hydrogen 3.120 N/A GLY 328.A N LEU 325.A O no hydrogen 2.751 N/A ILE 329.A N TYR 324.A O no hydrogen 2.924 N/A LEU 330.A N VAL 29.A O no hydrogen 2.830 N/A ARG 332.A N ARG 341.A O no hydrogen 3.008 N/A ARG 332.A NE ASN 32.A O no hydrogen 3.289 N/A ARG 332.A NH2 ASN 32.A O no hydrogen 3.364 N/A GLY 335.A N ASP 333.A OD1 no hydrogen 2.661 N/A LEU 340.A N PHE 311.A O no hydrogen 2.906 N/A ARG 341.A N ARG 332.A O no hydrogen 2.928 N/A ALA 342.A N VAL 309.A O no hydrogen 2.934 N/A THR 343.A N LEU 31.A O no hydrogen 3.137 N/A THR 343.A OG1 THR 33.A O no hydrogen 3.160 N/A THR 344.A N ASN 307.A O no hydrogen 2.957 N/A GLY 345.A N ASN 350.A OD1 no hydrogen 2.994 N/A LEU 346.A N GLU 349.A OE1 no hydrogen 2.728 N/A GLU 348.A N GLU 348.A OE1 no hydrogen 2.637 N/A ASN 350.A N LEU 346.A O no hydrogen 2.787 N/A ASN 350.A ND2 GLU 286.A OE1 no hydrogen 2.977 N/A ASP 351.A N ALA 347.A O no hydrogen 2.912 N/A ALA 352.A N GLU 348.A O no hydrogen 3.057 N/A PHE 353.A N GLU 349.A O no hydrogen 2.976 N/A LEU 354.A N ASN 350.A O no hydrogen 3.080 N/A ARG 355.A N ASP 351.A O no hydrogen 2.848 N/A ALA 356.A N ALA 352.A O no hydrogen 3.033 N/A SER 357.A N PHE 353.A O no hydrogen 2.811 N/A SER 357.A OG TYR 324.A OH no hydrogen 2.652 N/A SER 357.A OG PHE 353.A O no hydrogen 2.834 N/A ALA 358.A N LEU 354.A O no hydrogen 2.723 N/A ARG 359.A N ARG 355.A O no hydrogen 3.445 N/A ILE 360.A N ALA 356.A O no hydrogen 2.957 N/A THR 362.A N ARG 359.A O no hydrogen 3.314 N/A THR 362.A OG1 ARG 359.A O no hydrogen 3.211 N/A LEU 364.A N ALA 361.A O no hydrogen 3.160 N/A VAL 365.A N GLU 313.A O no hydrogen 3.191 N/A