Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4rf1_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 3.A N LEU 19.A O no hydrogen 2.794 N/A GLU 4.A N ASN 49.A OD1 no hydrogen 3.020 N/A VAL 5.A N VAL 17.A O no hydrogen 3.110 N/A LEU 6.A N HIS 51.A O no hydrogen 2.920 N/A VAL 7.A N ARG 15.A O no hydrogen 2.852 N/A THR 8.A N LEU 53.A O no hydrogen 2.935 N/A THR 8.A OG1 ASN 13.A O no hydrogen 2.860 N/A ASP 10.A N THR 8.A OG1 no hydrogen 3.118 N/A GLY 11.A N THR 8.A OG1 no hydrogen 2.790 N/A VAL 12.A N ASP 10.A OD1 no hydrogen 2.948 N/A ASN 13.A N ASP 10.A OD1 no hydrogen 2.871 N/A ARG 15.A N VAL 7.A O no hydrogen 3.076 N/A ARG 15.A NE GLU 63.A OE2 no hydrogen 2.520 N/A ARG 15.A NH2 GLU 63.A OE1 no hydrogen 3.315 N/A ARG 15.A NH2 GLU 63.A OE2 no hydrogen 3.362 N/A VAL 17.A N VAL 5.A O no hydrogen 2.905 N/A LEU 19.A N ILE 3.A O no hydrogen 2.871 N/A ASN 20.A N GLN 28.A OE1 no hydrogen 2.915 N/A ASN 21.A N LEU 1.A O no hydrogen 3.195 N/A LYS 22.A N ASN 20.A OD1 no hydrogen 3.027 N/A TYR 25.A N THR 42.A O no hydrogen 3.050 N/A TYR 25.A OH GLN 48.A OE1 no hydrogen 2.827 N/A ARG 26.A N SER 40.A O no hydrogen 2.872 N/A SER 27.A N THR 24.A OG1 no hydrogen 3.119 N/A GLN 28.A N THR 24.A O no hydrogen 3.060 N/A GLN 28.A N TYR 25.A O no hydrogen 3.173 N/A GLN 28.A NE2 ASN 20.A O no hydrogen 2.980 N/A GLN 28.A NE2 ASN 23.A O no hydrogen 2.849 N/A GLN 28.A NE2 THR 24.A O no hydrogen 3.647 N/A LEU 29.A N TYR 25.A O no hydrogen 2.699 N/A GLY 30.A N TYR 25.A O no hydrogen 3.027 N/A CYS 31.A N ASP 57.A OD1 no hydrogen 2.797 N/A CYS 31.A SG ASP 38.A OD2 no hydrogen 3.766 N/A CYS 31.A SG SER 40.A OG no hydrogen 3.612 N/A VAL 32.A N SER 40.A OG no hydrogen 2.926 N/A PHE 33.A N TYR 54.A O no hydrogen 2.829 N/A PHE 34.A N ALA 37.A O no hydrogen 2.708 N/A ALA 37.A N PHE 34.A O no hydrogen 3.095 N/A ILE 39.A N VAL 32.A O no hydrogen 3.131 N/A SER 40.A N ASP 38.A OD1 no hydrogen 2.934 N/A SER 40.A OG VAL 32.A O no hydrogen 3.539 N/A SER 40.A OG ASP 38.A OD1 no hydrogen 2.515 N/A THR 42.A N ILE 39.A O no hydrogen 3.075 N/A THR 42.A OG1 ILE 39.A O no hydrogen 2.654 N/A ASP 45.A N GLN 48.A OE1 no hydrogen 3.041 N/A GLU 46.A N ASP 45.A OD1 no hydrogen 2.429 N/A GLN 48.A N ASP 45.A O no hydrogen 3.150 N/A ASN 49.A N GLU 46.A O no hydrogen 3.156 N/A GLY 50.A N GLU 4.A O no hydrogen 2.635 N/A HIS 51.A N GLN 48.A O no hydrogen 3.105 N/A LEU 53.A N LEU 6.A O no hydrogen 2.608 N/A TYR 54.A N PHE 33.A O no hydrogen 2.954 N/A LEU 55.A N THR 8.A O no hydrogen 3.112 N/A ALA 56.A N CYS 31.A O no hydrogen 2.875 N/A THR 60.A N GLU 63.A OE1 no hydrogen 2.917 N/A GLU 63.A N THR 60.A OG1 no hydrogen 3.109 N/A THR 64.A N THR 60.A O no hydrogen 3.001 N/A THR 64.A OG1 THR 60.A O no hydrogen 2.772 N/A LYS 65.A N ALA 61.A O no hydrogen 3.125 N/A ALA 66.A N ASP 62.A O no hydrogen 3.010 N/A LEU 67.A N GLU 63.A O no hydrogen 2.861 N/A LYS 68.A N THR 64.A O no hydrogen 3.061 N/A GLU 69.A N LYS 65.A O no hydrogen 3.160 N/A LEU 70.A N ALA 66.A O no hydrogen 2.914 N/A TYR 71.A N LEU 67.A O no hydrogen 2.852 N/A THR 77.A N ASP 75.A OD1 no hydrogen 2.874 N/A THR 77.A OG1 ASP 75.A OD1 no hydrogen 2.308 N/A PHE 78.A N ASP 75.A O no hydrogen 3.059 N/A ARG 81.A N THR 77.A O no hydrogen 3.063 N/A ARG 81.A NE THR 77.A OG1 no hydrogen 3.097 N/A ARG 81.A NH1 ALA 153.A O no hydrogen 2.883 N/A ARG 81.A NH2 ASP 75.A OD2 no hydrogen 2.672 N/A PHE 82.A N PHE 78.A O no hydrogen 2.797 N/A TYR 83.A N LEU 79.A O no hydrogen 2.939 N/A SER 84.A N HIS 80.A O no hydrogen 2.814 N/A LEU 85.A N ARG 81.A O no hydrogen 2.813 N/A LYS 86.A N PHE 82.A O no hydrogen 2.957 N/A LYS 86.A NZ ASP 146.A OD1 no hydrogen 3.319 N/A ALA 87.A N TYR 83.A O no hydrogen 3.265 N/A ALA 88.A N SER 84.A O no hydrogen 3.013 N/A VAL 89.A N LEU 85.A O no hydrogen 2.911 N/A TRP 92.A N VAL 89.A O no hydrogen 3.233 N/A TRP 92.A NE1 ASP 107.A OD2 no hydrogen 3.022 N/A LYS 93.A NZ GLY 91.A O no hydrogen 2.991 N/A VAL 95.A N SER 102.A O no hydrogen 2.639 N/A CYS 97.A N.A VAL 100.A O no hydrogen 2.943 N/A CYS 97.A N.B VAL 100.A O no hydrogen 2.941 N/A VAL 100.A N CYS 97.A O.A no hydrogen 3.151 N/A VAL 100.A N CYS 97.A O.B no hydrogen 3.144 N/A ARG 101.A NH2 SER 144.A OG no hydrogen 2.974 N/A SER 102.A N VAL 95.A O no hydrogen 2.798 N/A SER 102.A OG ASN 113.A OD1 no hydrogen 2.687 N/A LEU 103.A N ASN 113.A OD1 no hydrogen 2.875 N/A LYS 104.A N LYS 93.A O no hydrogen 2.859 N/A LEU 105.A N SER 291.A O no hydrogen 3.059 N/A SER 106.A N ASN 109.A OD1 no hydrogen 2.964 N/A SER 106.A OG ASP 107.A OD2 no hydrogen 2.677 N/A ASN 108.A ND2 GLY 160.A O no hydrogen 2.801 N/A ASN 109.A N SER 106.A O no hydrogen 3.170 N/A ASN 109.A ND2 LYS 104.A O no hydrogen 3.140 N/A CYS 110.A SG HIS 277.A ND1 no hydrogen 3.647 N/A LEU 112.A N ASN 109.A O no hydrogen 2.932 N/A ASN 113.A N ASN 109.A O no hydrogen 3.141 N/A ASN 113.A ND2 PHE 289.A O no hydrogen 3.472 N/A ALA 114.A N CYS 110.A O no hydrogen 3.228 N/A VAL 115.A N TYR 111.A O no hydrogen 3.149 N/A ILE 116.A N LEU 112.A O no hydrogen 2.896 N/A MET 117.A N ASN 113.A O no hydrogen 2.927 N/A THR 118.A N ALA 114.A O no hydrogen 3.187 N/A THR 118.A OG1 ALA 114.A O no hydrogen 2.740 N/A LEU 119.A N VAL 115.A O no hydrogen 2.993 N/A ASP 120.A N ILE 116.A O no hydrogen 2.954 N/A LEU 121.A N THR 118.A O no hydrogen 3.039 N/A LEU 122.A N LEU 119.A O no hydrogen 3.055 N/A LYS 126.A N GLU 177.A O no hydrogen 2.968 N/A LYS 126.A NZ GLU 177.A OE2 no hydrogen 3.115 N/A PHE 127.A N GLN 133.A OE1 no hydrogen 2.718 N/A ALA 131.A N LEU 70.A O no hydrogen 3.104 N/A GLN 133.A N ILE 129.A O no hydrogen 2.965 N/A HIS 134.A N PRO 130.A O no hydrogen 2.841 N/A ALA 135.A N ALA 131.A O no hydrogen 2.939 N/A PHE 136.A N LEU 132.A O no hydrogen 2.857 N/A MET 137.A N GLN 133.A O no hydrogen 2.896 N/A LYS 138.A N HIS 134.A O no hydrogen 3.090 N/A LYS 138.A NZ ASP 146.A OD2 no hydrogen 2.843 N/A HIS 139.A N ALA 135.A O no hydrogen 2.940 N/A HIS 139.A ND1 SER 144.A OG no hydrogen 2.719 N/A HIS 139.A NE2 ASP 120.A OD1 no hydrogen 2.683 N/A LYS 140.A N PHE 136.A O no hydrogen 3.099 N/A GLY 141.A N LYS 138.A O no hydrogen 2.978 N/A GLY 142.A N HIS 139.A O no hydrogen 3.237 N/A ASP 143.A N LYS 138.A O no hydrogen 3.066 N/A SER 144.A OG HIS 139.A ND1 no hydrogen 2.719 N/A ILE 148.A N SER 144.A O no hydrogen 2.940 N/A ALA 149.A N THR 145.A O no hydrogen 3.024 N/A LEU 150.A N ASP 146.A O no hydrogen 2.885 N/A ILE 151.A N PHE 147.A O no hydrogen 3.038 N/A MET 152.A N ILE 148.A O no hydrogen 3.114 N/A ALA 153.A N ALA 149.A O no hydrogen 2.904 N/A TYR 154.A N LEU 150.A O no hydrogen 2.792 N/A TYR 154.A OH TYR 71.A O no hydrogen 2.665 N/A GLY 155.A N ILE 151.A O no hydrogen 2.835 N/A ASN 156.A N ALA 153.A O no hydrogen 3.104 N/A CYS 157.A N MET 152.A O no hydrogen 2.717 N/A CYS 157.A SG ASP 163.A OD2 no hydrogen 3.468 N/A ALA 161.A N THR 158.A O no hydrogen 3.070 N/A ASP 164.A N ASP 163.A OD1 no hydrogen 2.526 N/A ALA 165.A N TYR 278.A OH no hydrogen 3.253 N/A SER 166.A OG ASP 306.A OD1 no hydrogen 2.906 N/A SER 166.A OG ASP 306.A OD2 no hydrogen 2.493 N/A ARG 167.A N ASP 164.A OD1 no hydrogen 2.869 N/A ARG 167.A NH1 GLY 155.A O no hydrogen 3.007 N/A ARG 167.A NH2 GLY 155.A O no hydrogen 2.953 N/A LEU 168.A N ASP 164.A O no hydrogen 3.206 N/A LEU 169.A N ALA 165.A O no hydrogen 2.799 N/A HIS 170.A N SER 166.A O no hydrogen 3.046 N/A HIS 170.A NE2 SER 246.A OG no hydrogen 2.945 N/A THR 171.A N ARG 167.A O no hydrogen 3.091 N/A THR 171.A OG1 ARG 167.A O no hydrogen 2.780 N/A VAL 172.A N LEU 168.A O no hydrogen 2.853 N/A LEU 173.A N LEU 169.A O no hydrogen 2.916 N/A ALA 174.A N HIS 170.A O no hydrogen 2.980 N/A ALA 174.A N THR 171.A O no hydrogen 3.299 N/A LYS 175.A N VAL 172.A O no hydrogen 3.019 N/A ALA 176.A N LEU 173.A O no hydrogen 3.143 N/A GLU 177.A N LYS 126.A O no hydrogen 2.697 N/A CYS 179.A N ASP 124.A O no hydrogen 2.622 N/A CYS 179.A SG ASP 124.A O no hydrogen 3.754 N/A CYS 180.A SG ASP 124.A OD2 no hydrogen 3.445 N/A CYS 180.A SG SER 181.A O no hydrogen 3.827 N/A ARG 183.A N THR 239.A O no hydrogen 2.958 N/A MET 184.A N LEU 200.A O no hydrogen 2.864 N/A VAL 185.A N GLU 237.A O no hydrogen 2.856 N/A TRP 186.A N VAL 198.A O no hydrogen 2.847 N/A ARG 187.A N GLN 234.A O no hydrogen 2.918 N/A ARG 187.A NE ASP 197.A OD1 no hydrogen 2.823 N/A ARG 187.A NH2 ASP 197.A OD1 no hydrogen 3.518 N/A ARG 187.A NH2 ASP 197.A OD2 no hydrogen 2.757 N/A GLU 188.A N LYS 196.A O no hydrogen 2.758 N/A TRP 189.A N HIS 232.A O no hydrogen 3.220 N/A CYS 190.A N GLY 194.A O no hydrogen 3.039 N/A CYS 190.A SG GLU 230.A O no hydrogen 3.946 N/A GLY 194.A N CYS 190.A O no hydrogen 2.772 N/A LYS 196.A N GLU 188.A O no hydrogen 2.665 N/A VAL 198.A N TRP 186.A O no hydrogen 2.749 N/A LEU 200.A N MET 184.A O no hydrogen 2.757 N/A GLY 202.A N ALA 182.A O no hydrogen 3.100 N/A ALA 205.A N GLY 202.A O no hydrogen 3.051 N/A CYS 206.A N LEU 203.A O no hydrogen 2.833 N/A CYS 206.A SG GLY 202.A O no hydrogen 3.656 N/A CYS 207.A SG LEU 203.A O no hydrogen 3.787 N/A TYR 208.A N LEU 244.A O no hydrogen 3.164 N/A GLY 210.A N SER 246.A O no hydrogen 2.723 N/A GLN 212.A NE2 THR 248.A O no hydrogen 3.205 N/A GLN 212.A NE2 VAL 304.A O no hydrogen 2.951 N/A GLN 212.A NE2 THR 305.A O no hydrogen 2.596 N/A GLU 215.A N GLU 215.A OE1 no hydrogen 2.791 N/A ASP 216.A N THR 213.A OG1 no hydrogen 3.101 N/A LEU 217.A N THR 213.A O no hydrogen 3.133 N/A ARG 218.A N VAL 214.A O no hydrogen 3.030 N/A ARG 218.A NH2 GLN 312.A OE1 no hydrogen 2.848 N/A ARG 220.A NE GLN 234.A OE1 no hydrogen 2.791 N/A ARG 220.A NH2 GLN 234.A OE1 no hydrogen 3.074 N/A ARG 220.A NH2 ASN 319.A OXT no hydrogen 3.120 N/A MET 221.A N ARG 233.A O no hydrogen 2.700 N/A THR 222.A OG1 HIS 232.A ND1 no hydrogen 2.998 N/A TYR 223.A N ARG 231.A O no hydrogen 2.848 N/A CYS 225.A N GLY 229.A O no hydrogen 2.677 N/A GLY 228.A N CYS 225.A O no hydrogen 2.856 N/A ARG 231.A N TYR 223.A O no hydrogen 2.798 N/A ARG 231.A NH2 GLU 188.A OE1 no hydrogen 2.887 N/A HIS 232.A N TRP 189.A O no hydrogen 3.119 N/A HIS 232.A ND1 THR 222.A OG1 no hydrogen 2.998 N/A ARG 233.A N MET 221.A O no hydrogen 2.976 N/A GLN 234.A N ARG 187.A O no hydrogen 3.043 N/A VAL 236.A N VAL 185.A O no hydrogen 3.044 N/A HIS 238.A N TYR 314.A O no hydrogen 2.929 N/A HIS 238.A NE2 ALA 205.A O no hydrogen 2.759 N/A THR 239.A N ARG 183.A O no hydrogen 2.868 N/A THR 240.A N GLN 312.A O no hydrogen 2.972 N/A THR 240.A OG1 TRP 242.A O no hydrogen 2.912 N/A TRP 242.A NE1 LYS 123.A O no hydrogen 2.998 N/A LEU 243.A N PHE 309.A O no hydrogen 2.998 N/A LEU 244.A N CYS 206.A O no hydrogen 2.791 N/A LEU 245.A N VAL 307.A O no hydrogen 2.892 N/A SER 246.A N TYR 208.A O no hydrogen 2.982 N/A SER 246.A OG HIS 170.A NE2 no hydrogen 2.945 N/A SER 246.A OG ASP 306.A OD2 no hydrogen 2.531 N/A GLY 247.A N THR 305.A O no hydrogen 3.261 N/A ASN 250.A N VAL 304.A O no hydrogen 3.253 N/A LYS 252.A N CYS 302.A O no hydrogen 3.040 N/A VAL 254.A N TRP 300.A O no hydrogen 3.186 N/A THR 256.A N SER 298.A O no hydrogen 3.273 N/A SER 257.A N THR 255.A OG1 no hydrogen 3.170 N/A ALA 259.A N THR 256.A O no hydrogen 3.408 N/A VAL 263.A N LEU 308.A O no hydrogen 2.703 N/A ALA 264.A N LEU 308.A O no hydrogen 3.417 N/A PHE 265.A N ALA 281.A O no hydrogen 2.903 N/A ASN 266.A N ASP 306.A O no hydrogen 2.853 N/A ASN 266.A ND2 THR 118.A OG1 no hydrogen 2.975 N/A ASN 266.A ND2 ASP 306.A OD1 no hydrogen 3.304 N/A VAL 267.A N VAL 279.A O no hydrogen 2.917 N/A PHE 268.A N LYS 303.A O no hydrogen 3.031 N/A GLN 269.A N HIS 277.A O no hydrogen 2.745 N/A ALA 274.A N ILE 271.A O no hydrogen 3.431 N/A HIS 277.A N GLN 269.A O no hydrogen 2.940 N/A HIS 277.A NE2 ASP 290.A OD1 no hydrogen 2.566 N/A VAL 279.A N VAL 267.A O no hydrogen 2.983 N/A HIS 280.A N PHE 289.A O no hydrogen 3.382 N/A HIS 280.A ND1 ASN 266.A OD1 no hydrogen 2.739 N/A ALA 281.A N PHE 265.A O no hydrogen 2.922 N/A ARG 282.A N LEU 287.A O no hydrogen 2.811 N/A ARG 282.A NE HIS 280.A NE2 no hydrogen 3.047 N/A ARG 282.A NH2 MET 117.A O no hydrogen 2.898 N/A LEU 283.A N VAL 263.A O no hydrogen 2.935 N/A LYS 284.A N LEU 285.A O no hydrogen 3.372 N/A ILE 286.A N THR 297.A O no hydrogen 3.019 N/A LEU 287.A N ARG 282.A O no hydrogen 2.664 N/A LYS 288.A N SER 295.A O no hydrogen 2.800 N/A PHE 289.A N HIS 280.A O no hydrogen 2.641 N/A ASP 290.A N THR 293.A O no hydrogen 2.650 N/A THR 293.A N ASP 290.A O no hydrogen 3.169 N/A SER 295.A N LYS 288.A O no hydrogen 3.118 N/A THR 297.A N ILE 286.A O no hydrogen 3.294 N/A THR 297.A OG1 ASP 299.A O no hydrogen 3.131 N/A TRP 300.A N VAL 254.A O no hydrogen 3.060 N/A LYS 301.A NZ GLU 251.A OE2 no hydrogen 1.990 N/A CYS 302.A N LYS 252.A O no hydrogen 3.218 N/A CYS 302.A SG TRP 300.A O no hydrogen 3.672 N/A LYS 303.A NZ GLY 270.A O no hydrogen 2.753 N/A VAL 304.A N ASN 250.A O no hydrogen 3.183 N/A THR 305.A N ASN 266.A O no hydrogen 2.779 N/A VAL 307.A N LEU 245.A O no hydrogen 2.712 N/A LEU 308.A N ALA 264.A O no hydrogen 2.717 N/A PHE 309.A N LEU 243.A O no hydrogen 2.701 N/A GLN 312.A N THR 240.A O no hydrogen 2.883 N/A GLN 312.A N THR 240.A OG1 no hydrogen 3.301 N/A GLN 312.A NE2 PRO 310.A O no hydrogen 3.011 N/A TYR 314.A N HIS 238.A O no hydrogen 2.899 N/A SER 316.A N VAL 236.A O no hydrogen 2.947 N/A CYS 318.A N SER 316.A OG no hydrogen 3.236 N/A CYS 318.A SG GLN 234.A OE1 no hydrogen 4.026 N/A