Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4rvs_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 2.A N GLN 21.A O no hydrogen 2.751 N/A HIS 3.A N GLU 99.A OE1 no hydrogen 2.833 N/A ALA 4.A N VAL 19.A O no hydrogen 3.084 N/A ILE 5.A N TYR 97.A O no hydrogen 2.938 N/A GLU 6.A N ARG 17.A O no hydrogen 2.864 N/A VAL 7.A N PHE 58.A O no hydrogen 2.836 N/A GLY 11.A N ARG 48.A O no hydrogen 2.930 N/A VAL 15.A N GLY 12.A O no hydrogen 2.988 N/A LEU 16.A N PRO 13.A O no hydrogen 3.097 N/A ARG 17.A N GLU 6.A O no hydrogen 3.194 N/A VAL 19.A N ALA 4.A O no hydrogen 2.845 N/A GLN 21.A N MET 2.A O no hydrogen 2.787 N/A GLN 21.A NE2 GLU 6.A OE2 no hydrogen 3.566 N/A GLY 27.A N GLU 30.A OE1 no hydrogen 2.739 N/A GLY 29.A N PRO 73.A O no hydrogen 2.882 N/A GLU 30.A N GLY 27.A O no hydrogen 3.115 N/A LEU 31.A N ALA 103.A O no hydrogen 2.707 N/A LEU 32.A N ALA 70.A O no hydrogen 2.814 N/A ILE 33.A N CYS 101.A O no hydrogen 2.861 N/A LYS 34.A N THR 67.A O no hydrogen 2.823 N/A ALA 35.A N GLU 99.A O no hydrogen 2.907 N/A GLU 36.A N CYS 65.A O no hydrogen 2.753 N/A ALA 37.A N CYS 65.A O no hydrogen 3.049 N/A ILE 38.A N LEU 327.A O no hydrogen 2.808 N/A GLY 39.A N GLU 63.A O no hydrogen 2.959 N/A VAL 40.A N VAL 325.A O no hydrogen 3.096 N/A ASN 41.A N ASP 44.A OD2 no hydrogen 3.131 N/A ASN 41.A ND2 GLU 63.A OE1 no hydrogen 2.886 N/A ASP 44.A N ASN 41.A O no hydrogen 3.042 N/A ASP 44.A N ASN 41.A OD1 no hydrogen 3.084 N/A THR 45.A OG1 PHE 42.A O no hydrogen 2.663 N/A TYR 46.A N PHE 42.A O no hydrogen 3.180 N/A TYR 46.A N ILE 43.A O no hydrogen 3.079 N/A PHE 47.A N ILE 43.A O no hydrogen 3.162 N/A ARG 48.A N ASP 44.A O no hydrogen 2.928 N/A ARG 48.A NE GLY 11.A O no hydrogen 2.862 N/A ARG 48.A NH1 HIS 313.A ND1 no hydrogen 2.974 N/A ARG 48.A NH1 GLU 317.A OE1 no hydrogen 2.733 N/A ARG 48.A NH2 GLY 11.A O no hydrogen 3.560 N/A ARG 48.A NH2 GLU 317.A OE1 no hydrogen 2.778 N/A SER 49.A N THR 45.A O no hydrogen 2.910 N/A SER 49.A OG THR 45.A O no hydrogen 3.442 N/A SER 49.A OG TYR 46.A O no hydrogen 3.314 N/A GLY 50.A N PHE 47.A O no hydrogen 3.199 N/A GLN 51.A N SER 49.A OG no hydrogen 3.175 N/A TYR 52.A N TYR 46.A O no hydrogen 3.026 N/A PHE 58.A N VAL 7.A O no hydrogen 3.027 N/A ILE 60.A N ILE 5.A O no hydrogen 3.235 N/A SER 62.A OG ALA 91.A O no hydrogen 3.490 N/A VAL 64.A N SER 90.A O no hydrogen 3.010 N/A CYS 65.A N ALA 37.A O no hydrogen 2.946 N/A CYS 65.A SG VAL 88.A O no hydrogen 3.330 N/A GLY 66.A N VAL 88.A O no hydrogen 3.009 N/A THR 67.A N LYS 34.A O no hydrogen 2.994 N/A VAL 68.A N ASP 86.A O no hydrogen 2.949 N/A GLU 69.A N LEU 32.A O no hydrogen 2.738 N/A GLY 72.A N GLU 30.A O no hydrogen 2.818 N/A THR 76.A OG1 ASP 79.A OD2 no hydrogen 3.522 N/A ASP 79.A N THR 76.A O no hydrogen 3.047 N/A THR 80.A N THR 76.A O no hydrogen 3.230 N/A ILE 82.A N THR 80.A OG1 no hydrogen 3.094 N/A SER 83.A N ASP 86.A OD2 no hydrogen 2.828 N/A SER 83.A OG ALA 81.A O no hydrogen 3.529 N/A GLY 85.A N VAL 68.A O no hydrogen 2.786 N/A ASP 86.A N SER 83.A O no hydrogen 3.077 N/A ARG 87.A NH1 PRO 112.A O no hydrogen 3.076 N/A ARG 87.A NH1 VAL 115.A O no hydrogen 3.349 N/A ARG 87.A NH2 VAL 115.A O no hydrogen 2.852 N/A VAL 88.A N GLY 66.A O no hydrogen 2.793 N/A VAL 89.A N ALA 109.A O no hydrogen 2.785 N/A SER 90.A N VAL 64.A O no hydrogen 2.966 N/A SER 90.A OG LEU 107.A O no hydrogen 2.787 N/A SER 92.A N SER 90.A OG no hydrogen 2.970 N/A ALA 93.A N SER 62.A O no hydrogen 2.967 N/A ASN 94.A N THR 102.A O no hydrogen 2.842 N/A ALA 96.A N GLY 61.A O no hydrogen 3.017 N/A TYR 97.A N ILE 60.A O no hydrogen 2.921 N/A TYR 97.A OH ASP 44.A OD2 no hydrogen 2.673 N/A TYR 97.A OH HIS 313.A NE2 no hydrogen 2.846 N/A ALA 98.A N ALA 96.A O no hydrogen 2.730 N/A GLU 99.A N HIS 3.A O no hydrogen 3.147 N/A CYS 101.A N ILE 33.A O no hydrogen 2.956 N/A ALA 103.A N LEU 31.A O no hydrogen 3.125 N/A ALA 105.A N GLY 29.A O no hydrogen 2.879 N/A LEU 107.A N PRO 104.A O no hydrogen 3.041 N/A THR 108.A N ALA 105.A O no hydrogen 3.176 N/A THR 108.A OG1 PRO 104.A O no hydrogen 2.803 N/A ALA 109.A N VAL 89.A O no hydrogen 2.864 N/A LYS 110.A NZ ALA 81.A O no hydrogen 3.254 N/A VAL 111.A N ARG 87.A O no hydrogen 2.952 N/A VAL 115.A N PRO 112.A O no hydrogen 3.161 N/A GLU 118.A N GLU 118.A OE1 no hydrogen 2.703 N/A VAL 119.A N THR 116.A OG1 no hydrogen 3.300 N/A ALA 120.A N THR 116.A O no hydrogen 2.957 N/A ALA 121.A N SER 117.A O no hydrogen 2.940 N/A SER 122.A N GLU 118.A O no hydrogen 3.108 N/A SER 122.A OG GLU 118.A O no hydrogen 2.748 N/A ALA 123.A N ALA 120.A O no hydrogen 3.256 N/A LEU 124.A N ALA 120.A O no hydrogen 3.144 N/A LYS 126.A NZ SER 122.A O no hydrogen 2.832 N/A GLY 127.A N ALA 123.A O no hydrogen 2.724 N/A LEU 128.A N LEU 124.A O no hydrogen 2.791 N/A THR 129.A N LEU 125.A O no hydrogen 3.074 N/A THR 129.A OG1 LEU 125.A O no hydrogen 2.839 N/A ALA 130.A N LYS 126.A O no hydrogen 2.931 N/A HIS 131.A N GLY 127.A O no hydrogen 2.840 N/A HIS 131.A NE2 GLU 286.A OE1 no hydrogen 2.820 N/A TYR 132.A N LEU 128.A O no hydrogen 2.987 N/A LEU 133.A N THR 129.A O no hydrogen 3.109 N/A LEU 134.A N ALA 130.A O no hydrogen 3.043 N/A LYS 135.A N HIS 131.A O no hydrogen 2.833 N/A LYS 135.A NZ GLU 286.A OE1 no hydrogen 3.250 N/A SER 136.A N TYR 132.A O no hydrogen 2.951 N/A VAL 137.A N TYR 132.A O no hydrogen 2.858 N/A TYR 138.A N LEU 133.A O no hydrogen 3.314 N/A TYR 138.A OH ASP 144.A OD2 no hydrogen 2.573 N/A VAL 140.A N LEU 134.A O no hydrogen 3.017 N/A LYS 141.A N ASP 144.A OD2 no hydrogen 3.065 N/A LYS 141.A NZ TYR 138.A OH no hydrogen 3.321 N/A LYS 141.A NZ ASP 144.A OD1 no hydrogen 2.709 N/A LYS 141.A NZ ASP 144.A OD2 no hydrogen 3.563 N/A GLY 143.A N GLY 167.A O no hydrogen 3.020 N/A ASP 144.A N LYS 141.A O no hydrogen 3.060 N/A THR 145.A N GLN 215.A OE1 no hydrogen 2.828 N/A VAL 146.A N ARG 169.A O no hydrogen 2.845 N/A LEU 147.A N ALA 216.A O no hydrogen 3.009 N/A VAL 148.A N ILE 171.A O no hydrogen 2.774 N/A HIS 149.A N TYR 218.A O no hydrogen 3.133 N/A HIS 149.A ND1 THR 173.A OG1 no hydrogen 2.905 N/A HIS 149.A NE2 SER 229.A OG no hydrogen 2.673 N/A ALA 150.A N THR 173.A OG1 no hydrogen 3.295 N/A GLY 151.A N THR 173.A O no hydrogen 2.919 N/A GLY 153.A N ALA 150.A O no hydrogen 3.021 N/A LEU 157.A N GLY 153.A O no hydrogen 2.861 N/A ILE 158.A N GLY 154.A O no hydrogen 3.444 N/A LEU 159.A N VAL 155.A O no hydrogen 2.716 N/A THR 160.A N GLY 156.A O no hydrogen 2.910 N/A THR 160.A OG1 GLY 156.A O no hydrogen 2.776 N/A GLN 161.A N LEU 157.A O no hydrogen 3.079 N/A GLN 161.A NE2 LEU 157.A O no hydrogen 3.395 N/A GLN 161.A NE2 THR 297.A O no hydrogen 3.063 N/A TRP 162.A N ILE 158.A O no hydrogen 2.875 N/A ALA 163.A N LEU 159.A O no hydrogen 2.917 N/A THR 164.A N THR 160.A O no hydrogen 3.038 N/A THR 164.A OG1 THR 160.A O no hydrogen 2.756 N/A THR 164.A OG1 GLY 187.A O no hydrogen 3.360 N/A HIS 165.A N GLN 161.A O no hydrogen 2.982 N/A LEU 166.A N TRP 162.A O no hydrogen 3.022 N/A LEU 166.A N ALA 163.A O no hydrogen 3.004 N/A GLY 167.A N THR 164.A O no hydrogen 2.920 N/A VAL 168.A N ALA 163.A O no hydrogen 2.904 N/A ARG 169.A N ASP 144.A O no hydrogen 2.940 N/A ARG 169.A NE ASP 189.A OD2 no hydrogen 2.688 N/A ARG 169.A NH1 LEU 208.A O no hydrogen 2.689 N/A ARG 169.A NH2 ASP 189.A OD2 no hydrogen 3.265 N/A ILE 171.A N VAL 146.A O no hydrogen 2.884 N/A THR 172.A N VAL 190.A O no hydrogen 2.960 N/A THR 172.A OG1 SER 183.A OG no hydrogen 2.737 N/A THR 173.A N VAL 148.A O no hydrogen 3.302 N/A THR 173.A OG1 HIS 149.A ND1 no hydrogen 2.905 N/A VAL 174.A N LEU 192.A O no hydrogen 3.115 N/A GLU 178.A N GLU 178.A OE2 no hydrogen 2.837 N/A LYS 179.A N THR 176.A OG1 no hydrogen 3.114 N/A ALA 180.A N THR 176.A O no hydrogen 2.851 N/A LYS 181.A N ALA 177.A O no hydrogen 3.046 N/A LYS 181.A NZ ASP 185.A OD2 no hydrogen 3.199 N/A LEU 182.A N GLU 178.A O no hydrogen 3.201 N/A SER 183.A N LYS 179.A O no hydrogen 2.888 N/A SER 183.A OG THR 172.A OG1 no hydrogen 2.737 N/A LYS 184.A N ALA 180.A O no hydrogen 2.953 N/A ASP 185.A N LYS 181.A O no hydrogen 2.906 N/A ALA 186.A N LEU 182.A O no hydrogen 3.120 N/A ALA 186.A N SER 183.A O no hydrogen 3.131 N/A GLY 187.A N LYS 184.A O no hydrogen 2.992 N/A ALA 188.A N SER 183.A O no hydrogen 3.140 N/A ASP 189.A N VAL 170.A O no hydrogen 2.839 N/A LEU 192.A N THR 172.A O no hydrogen 2.753 N/A GLN 200.A N ASP 197.A OD2 no hydrogen 2.949 N/A PHE 201.A N ASP 197.A O no hydrogen 2.981 N/A ALA 202.A N ALA 198.A O no hydrogen 2.913 N/A GLY 203.A N TRP 199.A O no hydrogen 2.862 N/A ARG 204.A N GLN 200.A O no hydrogen 3.079 N/A ARG 204.A NH2 GLN 200.A OE1 no hydrogen 2.814 N/A VAL 205.A N PHE 201.A O no hydrogen 2.951 N/A ARG 206.A N ALA 202.A O no hydrogen 2.814 N/A ARG 206.A NH1 LEU 233.A O no hydrogen 3.320 N/A ARG 206.A NH2 ALA 231.A O no hydrogen 2.952 N/A ARG 206.A NH2 LEU 233.A O no hydrogen 2.865 N/A GLU 207.A N GLY 203.A O no hydrogen 3.048 N/A LEU 208.A N ARG 204.A O no hydrogen 3.130 N/A THR 209.A N VAL 205.A O no hydrogen 3.089 N/A THR 209.A N ARG 206.A O no hydrogen 3.180 N/A THR 209.A OG1 VAL 205.A O no hydrogen 2.857 N/A THR 209.A OG1 ARG 206.A O no hydrogen 3.399 N/A GLY 211.A N ARG 206.A O no hydrogen 2.593 N/A THR 212.A N THR 209.A O no hydrogen 3.220 N/A THR 212.A OG1 THR 209.A O no hydrogen 3.456 N/A GLY 213.A N THR 209.A OG1 no hydrogen 2.841 N/A VAL 214.A N SER 232.A O no hydrogen 3.017 N/A GLN 215.A N THR 145.A O no hydrogen 2.981 N/A VAL 217.A N THR 238.A O no hydrogen 2.949 N/A TYR 218.A N LEU 147.A O no hydrogen 2.808 N/A TYR 218.A OH LEU 133.A O no hydrogen 2.906 N/A ASP 219.A N ALA 240.A O no hydrogen 2.919 N/A VAL 221.A N ASP 219.A OD1 no hydrogen 2.829 N/A GLY 222.A N ASP 219.A OD1 no hydrogen 2.801 N/A ALA 223.A N GLY 247.A O no hydrogen 2.962 N/A THR 224.A N SER 246.A OG no hydrogen 2.996 N/A THR 224.A OG1 SER 246.A OG no hydrogen 3.351 N/A THR 225.A N GLY 222.A O no hydrogen 3.080 N/A THR 225.A OG1 ASP 219.A OD1 no hydrogen 3.019 N/A THR 225.A OG1 ASP 219.A OD2 no hydrogen 2.865 N/A THR 225.A OG1 GLY 222.A O no hydrogen 3.431 N/A PHE 226.A N GLY 222.A O no hydrogen 2.878 N/A SER 229.A N THR 225.A O no hydrogen 2.904 N/A SER 229.A OG HIS 149.A NE2 no hydrogen 2.673 N/A SER 229.A OG ASP 219.A OD2 no hydrogen 2.813 N/A SER 229.A OG THR 225.A O no hydrogen 3.129 N/A LEU 230.A N PHE 226.A O no hydrogen 2.939 N/A ALA 231.A N ASP 227.A O no hydrogen 3.066 N/A SER 232.A N SER 229.A O no hydrogen 3.187 N/A SER 232.A OG ALA 228.A O no hydrogen 2.728 N/A ALA 234.A N VAL 214.A O no hydrogen 2.723 N/A ARG 236.A N GLY 261.A O no hydrogen 2.773 N/A GLY 237.A N ALA 234.A O no hydrogen 2.886 N/A THR 238.A N GLN 215.A O no hydrogen 3.143 N/A LEU 239.A N TYR 264.A O no hydrogen 2.800 N/A ALA 240.A N VAL 217.A O no hydrogen 2.844 N/A LEU 241.A N THR 266.A O no hydrogen 2.954 N/A PHE 242.A N ASP 219.A O no hydrogen 2.911 N/A ALA 245.A N GLY 220.A O no hydrogen 3.200 N/A SER 246.A N VAL 221.A O no hydrogen 2.813 N/A SER 246.A OG VAL 221.A O no hydrogen 2.807 N/A SER 246.A OG THR 224.A OG1 no hydrogen 3.351 N/A GLY 247.A N ALA 244.A O no hydrogen 3.009 N/A GLN 255.A N ASP 253.A OD1 no hydrogen 3.066 N/A ARG 256.A N ASP 253.A O no hydrogen 2.828 N/A ARG 256.A NH2 ASP 227.A OD1 no hydrogen 2.876 N/A LEU 257.A N PRO 254.A O no hydrogen 2.880 N/A ALA 259.A N GLN 255.A O no hydrogen 2.988 N/A ALA 260.A N ARG 256.A O no hydrogen 3.024 N/A GLY 261.A N ASN 258.A O no hydrogen 2.935 N/A SER 262.A N ASN 258.A O no hydrogen 3.106 N/A VAL 263.A N LEU 257.A O no hydrogen 3.074 N/A TYR 264.A N GLY 237.A O no hydrogen 2.869 N/A THR 266.A N LEU 239.A O no hydrogen 3.037 N/A ARG 267.A NH1 PRO 268.A O no hydrogen 3.018 N/A HIS 272.A N SER 269.A O no hydrogen 3.122 N/A PHE 273.A N LEU 270.A O no hydrogen 2.828 N/A THR 274.A N PHE 271.A O no hydrogen 3.504 N/A THR 274.A OG1 LEU 270.A O no hydrogen 3.134 N/A ARG 275.A N GLU 279.A OE1 no hydrogen 2.967 N/A GLU 279.A N THR 276.A OG1 no hydrogen 3.117 N/A PHE 280.A N THR 276.A O no hydrogen 2.973 N/A SER 281.A N GLY 277.A O no hydrogen 2.809 N/A SER 281.A OG GLY 277.A O no hydrogen 2.888 N/A TRP 282.A N GLU 278.A O no hydrogen 3.112 N/A TRP 282.A NE1 GLU 286.A OE2 no hydrogen 3.100 N/A ARG 283.A N GLU 279.A O no hydrogen 3.172 N/A ARG 283.A NE PHE 273.A O no hydrogen 2.786 N/A ARG 283.A NH1 HIS 131.A ND1 no hydrogen 2.992 N/A ARG 283.A NH1 SER 136.A OG no hydrogen 2.987 N/A ARG 283.A NH2 SER 136.A OG no hydrogen 3.026 N/A ARG 283.A NH2 GLU 279.A OE2 no hydrogen 2.831 N/A ALA 284.A N PHE 280.A O no hydrogen 3.015 N/A ALA 285.A N SER 281.A O no hydrogen 2.863 N/A GLU 286.A N TRP 282.A O no hydrogen 3.150 N/A LEU 287.A N ARG 283.A O no hydrogen 2.975 N/A PHE 288.A N ALA 284.A O no hydrogen 2.859 N/A ASP 289.A N ALA 285.A O no hydrogen 2.914 N/A ALA 290.A N GLU 286.A O no hydrogen 3.163 N/A ILE 291.A N LEU 287.A O no hydrogen 2.968 N/A GLY 292.A N PHE 288.A O no hydrogen 2.867 N/A ASN 293.A N ASP 289.A O no hydrogen 2.931 N/A GLU 294.A N ILE 291.A O no hydrogen 2.882 N/A ALA 295.A N ALA 290.A O no hydrogen 2.918 N/A ILE 296.A N ALA 290.A O no hydrogen 3.283 N/A THR 297.A N GLN 161.A OE1 no hydrogen 2.850 N/A THR 297.A OG1 GLN 161.A OE1 no hydrogen 3.388 N/A GLY 301.A N SER 324.A O no hydrogen 2.794 N/A GLY 302.A N SER 324.A O no hydrogen 3.235 N/A ARG 303.A NH2 GLU 118.A OE2 no hydrogen 2.388 N/A TYR 304.A N VAL 326.A O no hydrogen 2.983 N/A TYR 304.A OH ASP 315.A OD2 no hydrogen 2.445 N/A LEU 306.A N LEU 328.A O no hydrogen 3.157 N/A ASP 308.A N PRO 305.A O no hydrogen 2.947 N/A ALA 309.A N LEU 306.A O no hydrogen 3.221 N/A ALA 312.A N ASP 308.A O no hydrogen 2.978 N/A HIS 313.A N ALA 309.A O no hydrogen 2.940 N/A HIS 313.A NE2 TYR 97.A OH no hydrogen 2.846 N/A GLN 314.A N LEU 310.A O no hydrogen 2.987 N/A ASP 315.A N ARG 311.A O no hydrogen 2.882 N/A LEU 316.A N ALA 312.A O no hydrogen 2.815 N/A GLU 317.A N HIS 313.A O no hydrogen 2.973 N/A ALA 318.A N GLN 314.A O no hydrogen 2.962 N/A ARG 319.A N LEU 316.A O no hydrogen 3.255 N/A LYS 320.A N ASP 315.A O no hydrogen 2.966 N/A THR 321.A OG1 THR 321.A O no hydrogen 2.395 N/A SER 324.A N ALA 299.A O no hydrogen 2.910 N/A SER 324.A OG ALA 299.A O no hydrogen 3.510 N/A VAL 326.A N GLY 302.A O no hydrogen 2.857 N/A LEU 327.A N ILE 38.A O no hydrogen 2.808 N/A LEU 328.A N TYR 304.A O no hydrogen 2.789 N/A