Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4rwq_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 8.A N LYS 333.A O no hydrogen 3.286 N/A LEU 11.A N ASP 10.A OD1 no hydrogen 2.320 N/A ASP 12.A N ASP 10.A O no hydrogen 2.444 N/A PHE 14.A N LEU 11.A O no hydrogen 3.091 N/A ILE 15.A N LEU 11.A O no hydrogen 3.350 N/A GLU 16.A N ASP 12.A O no hydrogen 2.757 N/A HIS 18.A N PHE 14.A O no hydrogen 3.042 N/A LEU 20.A N ILE 15.A O no hydrogen 2.841 N/A CYS 24.A N ASN 22.A OD1 no hydrogen 2.999 N/A ARG 26.A N ASN 22.A O no hydrogen 3.088 N/A THR 27.A N THR 23.A O no hydrogen 3.399 N/A THR 27.A OG1 THR 23.A O no hydrogen 3.037 N/A GLN 28.A N CYS 24.A O no hydrogen 3.239 N/A VAL 29.A N PHE 25.A O no hydrogen 3.009 N/A LYS 30.A N ARG 26.A O no hydrogen 2.826 N/A GLU 31.A N THR 27.A O no hydrogen 3.195 N/A ALA 32.A N GLN 28.A O no hydrogen 3.041 N/A ILE 33.A N VAL 29.A O no hydrogen 2.844 N/A ASP 34.A N LYS 30.A O no hydrogen 3.192 N/A ILE 35.A N GLU 31.A O no hydrogen 2.996 N/A VAL 36.A N ALA 32.A O no hydrogen 3.033 N/A CYS 37.A N ILE 33.A O no hydrogen 2.641 N/A ARG 38.A N ASP 34.A O no hydrogen 3.105 N/A PHE 39.A N ILE 35.A O no hydrogen 2.922 N/A LEU 40.A N VAL 36.A O no hydrogen 2.724 N/A LYS 41.A N CYS 37.A O no hydrogen 3.351 N/A ARG 43.A N PHE 39.A O no hydrogen 2.876 N/A ARG 43.A NE GLN 104.A OE1 no hydrogen 3.412 N/A ARG 43.A NH1 GLU 111.A OE1 no hydrogen 2.393 N/A ARG 43.A NH1 GLU 111.A OE2 no hydrogen 3.103 N/A ARG 43.A NH2 GLU 111.A OE2 no hydrogen 3.263 N/A CYS 44.A N LEU 40.A O no hydrogen 3.030 N/A PHE 45.A N GLU 100.A OE2 no hydrogen 2.565 N/A THR 48.A OG1 GLN 46.A O no hydrogen 2.280 N/A VAL 52.A N ASP 50.A OD1 no hydrogen 3.167 N/A SER 55.A N PHE 80.A O no hydrogen 2.900 N/A SER 55.A OG PHE 80.A O no hydrogen 3.354 N/A SER 55.A OG ASP 153.A OD2 no hydrogen 3.035 N/A LYS 56.A NZ ASP 153.A OD1 no hydrogen 3.496 N/A LYS 56.A NZ GLY 156.A O no hydrogen 2.643 N/A LYS 56.A NZ GLU 191.A OE1 no hydrogen 2.791 N/A LYS 56.A NZ GLU 191.A OE2 no hydrogen 3.027 N/A VAL 58.A N VAL 78.A O no hydrogen 3.208 N/A GLY 60.A N ASP 76.A O no hydrogen 2.504 N/A SER 63.A N ASP 74.A O no hydrogen 2.992 N/A LYS 65.A N ARG 72.A O no hydrogen 2.680 N/A LYS 65.A NZ GLY 66.A O no hydrogen 3.452 N/A LEU 69.A N THR 68.A OG1 no hydrogen 2.534 N/A ARG 72.A NH1 GLU 145.A OE1 no hydrogen 3.351 N/A ARG 72.A NH2 ASP 74.A OD1 no hydrogen 3.165 N/A SER 73.A N GLU 143.A O no hydrogen 3.074 N/A ASP 74.A N SER 63.A O no hydrogen 2.983 N/A ALA 75.A N GLU 145.A O no hydrogen 3.103 N/A ASP 76.A N GLY 61.A O no hydrogen 3.124 N/A LEU 77.A N ASP 147.A O no hydrogen 2.868 N/A VAL 78.A N VAL 58.A O no hydrogen 3.006 N/A PHE 80.A N LYS 56.A O no hydrogen 3.001 N/A LEU 81.A N ALA 151.A O no hydrogen 2.894 N/A THR 82.A N ARG 53.A O no hydrogen 2.933 N/A THR 82.A OG1 ARG 53.A O no hydrogen 3.194 N/A SER 86.A N ASP 89.A OD2 no hydrogen 3.008 N/A PHE 87.A N GLU 175.A OE1 no hydrogen 3.388 N/A GLU 88.A N GLU 175.A OE2 no hydrogen 2.989 N/A ASP 89.A N SER 86.A O no hydrogen 3.218 N/A GLN 90.A N PHE 87.A O no hydrogen 3.325 N/A LEU 91.A N GLU 88.A O no hydrogen 3.029 N/A ARG 92.A N GLU 88.A O no hydrogen 3.139 N/A ARG 93.A N ASP 89.A O no hydrogen 2.798 N/A ARG 93.A NE GLU 96.A OE1 no hydrogen 2.843 N/A ARG 93.A NH1 ASP 50.A OD2 no hydrogen 3.372 N/A ARG 93.A NH1 GLU 96.A OE1 no hydrogen 3.366 N/A ARG 93.A NH1 GLU 96.A OE2 no hydrogen 3.158 N/A PHE 97.A N ARG 93.A O no hydrogen 2.910 N/A ILE 98.A N ARG 94.A O no hydrogen 2.798 N/A ILE 101.A N PHE 97.A O no hydrogen 3.013 N/A ARG 102.A N ILE 98.A O no hydrogen 3.132 N/A ARG 103.A N GLN 99.A O no hydrogen 2.965 N/A GLN 104.A N GLU 100.A O no hydrogen 3.361 N/A LEU 105.A N ILE 101.A O no hydrogen 2.837 N/A GLU 106.A N ARG 102.A O no hydrogen 3.119 N/A ALA 107.A N ARG 103.A O no hydrogen 3.305 N/A CYS 108.A N GLN 104.A O no hydrogen 2.625 N/A GLN 109.A N LEU 105.A O no hydrogen 3.115 N/A ARG 110.A N GLU 106.A O no hydrogen 3.350 N/A GLU 111.A N ALA 107.A O no hydrogen 2.941 N/A GLN 112.A N CYS 108.A O no hydrogen 2.878 N/A THR 117.A N SER 136.A O no hydrogen 2.949 N/A THR 117.A OG1 SER 136.A O no hydrogen 2.467 N/A GLU 119.A N VAL 134.A O no hydrogen 2.906 N/A GLN 121.A N SER 132.A O no hydrogen 3.181 N/A ARG 124.A NH2 GLU 145.A OE2 no hydrogen 2.324 N/A SER 132.A OG GLU 145.A OE2 no hydrogen 2.671 N/A PHE 133.A N PHE 146.A O no hydrogen 3.080 N/A VAL 134.A N GLU 119.A O no hydrogen 2.616 N/A LEU 135.A N VAL 144.A O no hydrogen 2.723 N/A SER 136.A N THR 117.A O no hydrogen 3.434 N/A SER 136.A OG THR 117.A OG1 no hydrogen 2.545 N/A SER 137.A N GLN 142.A O no hydrogen 2.909 N/A SER 137.A OG GLN 139.A OE1 no hydrogen 3.046 N/A GLN 139.A N GLN 139.A OE1 no hydrogen 2.637 N/A LEU 140.A N SER 137.A O no hydrogen 2.953 N/A GLN 142.A N SER 137.A O no hydrogen 3.392 N/A VAL 144.A N LEU 135.A O no hydrogen 2.953 N/A GLU 145.A N SER 73.A O no hydrogen 3.176 N/A PHE 146.A N PHE 133.A O no hydrogen 2.845 N/A ASP 147.A N ALA 75.A O no hydrogen 2.920 N/A LEU 149.A N LEU 77.A O no hydrogen 2.884 N/A ALA 151.A N VAL 79.A O no hydrogen 2.880 N/A ASP 153.A N LEU 81.A O no hydrogen 2.914 N/A GLY 156.A N ASP 153.A OD1 no hydrogen 2.955 N/A TRP 158.A NE1 TYR 162.A O no hydrogen 2.499 N/A TYR 162.A N THR 159.A O no hydrogen 3.270 N/A LYS 163.A NZ GLU 273.A O no hydrogen 3.509 N/A LYS 163.A NZ ASP 277.A OD1 no hydrogen 3.514 N/A GLU 167.A N ASN 165.A OD1 no hydrogen 2.986 N/A ILE 168.A N ASN 165.A O no hydrogen 2.899 N/A TYR 169.A OH ALA 302.A O no hydrogen 3.363 N/A VAL 170.A N PRO 166.A O no hydrogen 2.996 N/A GLN 171.A N GLU 167.A O no hydrogen 3.140 N/A LEU 172.A N ILE 168.A O no hydrogen 3.170 N/A ILE 173.A N TYR 169.A O no hydrogen 2.906 N/A LYS 174.A N VAL 170.A O no hydrogen 3.020 N/A GLU 175.A N GLN 171.A O no hydrogen 3.146 N/A CYS 176.A N LEU 172.A O no hydrogen 2.850 N/A CYS 176.A SG LYS 181.A O no hydrogen 3.682 N/A LYS 177.A N ILE 173.A O no hydrogen 2.787 N/A SER 178.A N LYS 174.A O no hydrogen 3.272 N/A SER 178.A OG LYS 174.A O no hydrogen 3.224 N/A SER 178.A OG GLU 175.A O no hydrogen 3.314 N/A ARG 179.A N GLU 175.A O no hydrogen 3.095 N/A SER 186.A OG GLY 183.A O no hydrogen 3.042 N/A SER 186.A OG ASP 303.A OD2 no hydrogen 2.217 N/A CYS 188.A N PHE 185.A O no hydrogen 3.061 N/A CYS 188.A SG PHE 152.A O no hydrogen 3.291 N/A CYS 188.A SG PHE 185.A O no hydrogen 3.362 N/A PHE 189.A N SER 186.A O no hydrogen 3.039 N/A THR 190.A N THR 187.A O no hydrogen 3.362 N/A THR 190.A OG1 THR 187.A O no hydrogen 2.415 N/A LEU 192.A N PHE 189.A O no hydrogen 2.775 N/A GLN 193.A N PHE 189.A O no hydrogen 3.332 N/A ARG 194.A N THR 190.A O no hydrogen 2.994 N/A ARG 194.A NH1 LYS 59.A O no hydrogen 3.173 N/A ASP 195.A N GLU 191.A O no hydrogen 3.110 N/A PHE 196.A N LEU 192.A O no hydrogen 3.007 N/A ASN 199.A ND2 ASP 195.A O no hydrogen 2.385 N/A ASN 199.A ND2 PHE 196.A O no hydrogen 3.206 N/A ARG 200.A NE PHE 196.A O no hydrogen 3.093 N/A LYS 205.A N PRO 201.A O no hydrogen 3.004 N/A SER 206.A N THR 202.A O no hydrogen 2.985 N/A SER 206.A OG THR 202.A O no hydrogen 3.254 N/A SER 206.A OG LYS 203.A O no hydrogen 2.560 N/A LEU 207.A N LYS 203.A O no hydrogen 3.103 N/A ILE 208.A N LEU 204.A O no hydrogen 2.868 N/A ARG 209.A N LYS 205.A O no hydrogen 3.198 N/A LEU 210.A N SER 206.A O no hydrogen 3.190 N/A VAL 211.A N LEU 207.A O no hydrogen 3.039 N/A LYS 212.A N ILE 208.A O no hydrogen 2.710 N/A HIS 213.A N ARG 209.A O no hydrogen 3.201 N/A TRP 214.A N LEU 210.A O no hydrogen 3.231 N/A TYR 215.A N VAL 211.A O no hydrogen 3.146 N/A TYR 215.A OH PRO 227.A O no hydrogen 2.822 N/A GLN 216.A N LYS 212.A O no hydrogen 3.322 N/A GLN 216.A NE2 GLY 64.A O no hydrogen 3.248 N/A THR 217.A N HIS 213.A O no hydrogen 3.036 N/A THR 217.A OG1 HIS 213.A O no hydrogen 3.400 N/A THR 217.A OG1 TRP 214.A O no hydrogen 2.497 N/A CYS 218.A N TRP 214.A O no hydrogen 3.367 N/A CYS 218.A SG TRP 214.A O no hydrogen 3.413 N/A CYS 218.A SG GLU 322.A OE1 no hydrogen 3.276 N/A LYS 219.A N GLN 216.A O no hydrogen 3.242 N/A LYS 219.A NZ ASN 224.A OD1 no hydrogen 3.043 N/A THR 221.A N CYS 218.A O no hydrogen 3.285 N/A HIS 222.A N CYS 218.A O no hydrogen 3.195 N/A GLY 223.A N LYS 219.A O no hydrogen 3.208 N/A GLN 229.A NE2 LYS 212.A O no hydrogen 3.489 N/A TYR 230.A OH ASP 300.A OD1 no hydrogen 3.108 N/A ALA 231.A N PRO 228.A O no hydrogen 3.250 N/A LEU 232.A N GLN 229.A O no hydrogen 3.072 N/A GLU 233.A N GLN 229.A O no hydrogen 3.228 N/A LEU 234.A N TYR 230.A O no hydrogen 3.114 N/A LEU 235.A N ALA 231.A O no hydrogen 3.007 N/A THR 236.A N LEU 232.A O no hydrogen 3.075 N/A THR 236.A OG1 LEU 232.A O no hydrogen 2.846 N/A VAL 237.A N GLU 233.A O no hydrogen 3.228 N/A TYR 238.A N LEU 234.A O no hydrogen 3.019 N/A ALA 239.A N LEU 235.A O no hydrogen 3.001 N/A TRP 240.A N THR 236.A O no hydrogen 3.193 N/A TRP 240.A NE1 LYS 246.A O no hydrogen 3.040 N/A GLU 241.A N VAL 237.A O no hydrogen 2.857 N/A GLN 242.A N TYR 238.A O no hydrogen 3.121 N/A SER 244.A OG TRP 240.A O no hydrogen 2.271 N/A ARG 245.A N TRP 240.A O no hydrogen 3.249 N/A ARG 245.A N SER 244.A OG no hydrogen 2.593 N/A ARG 245.A NE GLU 241.A O no hydrogen 2.670 N/A THR 251.A OG1 ASP 12.A OD1 no hydrogen 3.253 N/A THR 251.A OG1 ASP 12.A OD2 no hydrogen 3.054 N/A GLY 254.A N SER 250.A O no hydrogen 3.279 N/A PHE 255.A N THR 251.A O no hydrogen 2.884 N/A GLN 256.A N ALA 252.A O no hydrogen 3.185 N/A THR 257.A N GLN 253.A O no hydrogen 3.056 N/A THR 257.A OG1 GLN 253.A O no hydrogen 2.678 N/A VAL 258.A N GLY 254.A O no hydrogen 2.982 N/A LEU 259.A N PHE 255.A O no hydrogen 3.279 N/A GLU 260.A N GLN 256.A O no hydrogen 3.204 N/A LEU 261.A N VAL 258.A O no hydrogen 3.141 N/A VAL 262.A N LEU 259.A O no hydrogen 3.322 N/A LYS 264.A N LEU 261.A O no hydrogen 3.050 N/A HIS 265.A ND1 VAL 262.A O no hydrogen 2.786 N/A LYS 267.A N LYS 264.A O no hydrogen 2.623 N/A LEU 268.A N HIS 265.A O no hydrogen 3.069 N/A CYS 269.A SG LEU 291.A O no hydrogen 3.703 N/A ILE 270.A N VAL 297.A O no hydrogen 3.051 N/A TRP 272.A NE1 GLU 241.A OE1 no hydrogen 2.905 N/A TYR 275.A OH ASP 195.A OD2 no hydrogen 2.766 N/A TYR 276.A OH ASP 300.A O no hydrogen 2.655 N/A THR 279.A N ASP 277.A OD2 no hydrogen 3.455 N/A THR 279.A OG1 ASP 277.A OD2 no hydrogen 2.585 N/A VAL 283.A N ASN 280.A OD1 no hydrogen 3.108 N/A GLY 284.A N ASN 280.A O no hydrogen 2.847 N/A ARG 285.A N PRO 281.A O no hydrogen 3.213 N/A CYS 286.A N VAL 282.A O no hydrogen 3.391 N/A MET 287.A N VAL 283.A O no hydrogen 2.955 N/A LEU 288.A N GLY 284.A O no hydrogen 3.022 N/A GLN 289.A N ARG 285.A O no hydrogen 2.905 N/A GLN 290.A N CYS 286.A O no hydrogen 3.384 N/A GLN 290.A NE2 GLU 182.A OE1 no hydrogen 3.324 N/A LYS 292.A N LEU 288.A O no hydrogen 3.351 N/A LYS 293.A N GLN 290.A O no hydrogen 3.252 N/A LYS 293.A NZ ASN 307.A OD1 no hydrogen 3.151 N/A ARG 295.A NH2 LEU 291.A O no hydrogen 3.281 N/A VAL 297.A N LEU 268.A O no hydrogen 3.299 N/A LEU 299.A N ILE 270.A O no hydrogen 2.958 N/A ASP 300.A N GLY 306.A O no hydrogen 3.227 N/A ALA 302.A N ASP 300.A OD1 no hydrogen 3.071 N/A ASP 303.A N ASP 300.A O no hydrogen 2.942 N/A THR 305.A OG1 ASP 303.A OD1 no hydrogen 2.790 N/A ASN 307.A ND2 ILE 298.A O no hydrogen 3.111 N/A VAL 308.A N ILE 298.A O no hydrogen 2.807 N/A HIS 314.A N ASP 312.A OD1 no hydrogen 2.741 N/A SER 315.A OG LYS 225.A O no hydrogen 2.671 N/A TRP 316.A NE1 GLY 309.A O no hydrogen 2.396 N/A ARG 318.A N HIS 314.A O no hydrogen 3.119 N/A LEU 319.A N SER 315.A O no hydrogen 3.127 N/A ALA 320.A N TRP 316.A O no hydrogen 2.546 N/A GLN 321.A N GLN 317.A O no hydrogen 2.940 N/A ALA 323.A N LEU 319.A O no hydrogen 2.831 N/A ARG 324.A N ALA 320.A O no hydrogen 2.938 N/A VAL 325.A N GLN 321.A O no hydrogen 3.374 N/A TRP 326.A N GLU 322.A O no hydrogen 3.137 N/A LEU 327.A N ARG 324.A O no hydrogen 3.284 N/A GLY 328.A N VAL 325.A O no hydrogen 3.000 N/A TYR 329.A N TRP 326.A O no hydrogen 3.307 N/A CYS 331.A SG LEU 3.A O no hydrogen 2.826 N/A CYS 331.A SG ARG 4.A O no hydrogen 2.900 N/A CYS 332.A N TYR 329.A O no hydrogen 3.407 N/A CYS 332.A SG TRP 326.A O no hydrogen 3.904 N/A LYS 333.A N PRO 330.A O no hydrogen 2.923 N/A ASN 334.A N SER 338.A O no hydrogen 3.149 N/A GLY 337.A N ASN 334.A O no hydrogen 2.940 N/A VAL 340.A N CYS 332.A O no hydrogen 3.392 N/A TRP 343.A N THR 257.A OG1 no hydrogen 2.759 N/A