Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4rz8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TRP 2.A NE1 GLU 48.A OE2 no hydrogen 2.745 N/A LYS 3.A N GLN 337.A O no hydrogen 3.203 N/A ALA 5.A N VAL 335.A O no hydrogen 3.339 N/A LEU 9.A N GLN 60.A OE1 no hydrogen 3.123 N/A PHE 10.A N CYS 102.A O no hydrogen 3.206 N/A CYS 11.A SG ALA 30.A O no hydrogen 3.291 N/A ALA 12.A N HIS 100.A O no hydrogen 2.829 N/A SER 13.A N VAL 32.A O no hydrogen 3.026 N/A LYS 16.A N ASN 24.A OD1 no hydrogen 3.080 N/A VAL 22.A N SER 93.A O no hydrogen 3.066 N/A HIS 23.A N GLU 21.A OE2 no hydrogen 3.136 N/A HIS 23.A ND1 GLU 21.A OE2 no hydrogen 2.686 N/A ASN 24.A N GLU 21.A OE1 no hydrogen 2.580 N/A ASN 24.A ND2 GLU 21.A OE1 no hydrogen 2.818 N/A VAL 25.A N GLU 21.A O no hydrogen 2.859 N/A TRP 26.A N VAL 22.A O no hydrogen 2.915 N/A ALA 27.A N HIS 23.A O no hydrogen 3.016 N/A THR 28.A N ASN 24.A O no hydrogen 3.019 N/A THR 28.A OG1 LYS 16.A O no hydrogen 3.380 N/A THR 28.A OG1 ASN 24.A O no hydrogen 2.535 N/A HIS 29.A N TRP 26.A O no hydrogen 3.297 N/A ALA 30.A N TRP 26.A O no hydrogen 2.907 N/A CYS 31.A N ALA 27.A O no hydrogen 2.886 N/A VAL 32.A N CYS 11.A O no hydrogen 2.937 N/A THR 34.A OG1 ASP 14.A OD1 no hydrogen 2.457 N/A ASN 37.A N ASP 35.A OD1 no hydrogen 3.005 N/A ILE 41.A N SER 128.A O no hydrogen 2.969 N/A LEU 43.A N VAL 126.A O no hydrogen 3.081 N/A GLU 48.A N CYS 123.A O no hydrogen 3.316 N/A PHE 50.A N GLY 121.A O no hydrogen 2.692 N/A MET 52.A N GLY 119.A O no hydrogen 3.180 N/A TRP 53.A N ASN 51.A OD1 no hydrogen 3.138 N/A LYS 54.A N ASN 51.A O no hydrogen 2.975 N/A ASN 55.A ND2 LEU 330.A O no hydrogen 3.539 N/A ASN 55.A ND2 TYR 333.A O no hydrogen 2.847 N/A MET 57.A N ASN 55.A OD1 no hydrogen 2.974 N/A VAL 58.A N ASN 55.A O no hydrogen 2.997 N/A GLN 60.A N ASN 56.A O no hydrogen 3.096 N/A GLN 60.A NE2 THR 7.A O no hydrogen 2.633 N/A GLN 60.A NE2 ASN 56.A OD1 no hydrogen 2.621 N/A MET 61.A N MET 57.A O no hydrogen 3.112 N/A GLN 62.A N VAL 58.A O no hydrogen 2.938 N/A GLU 63.A N GLU 59.A O no hydrogen 2.971 N/A ASP 64.A N GLN 60.A O no hydrogen 3.137 N/A VAL 65.A N MET 61.A O no hydrogen 2.964 N/A ILE 66.A N GLN 62.A O no hydrogen 2.978 N/A SER 67.A N GLU 63.A O no hydrogen 3.011 N/A LEU 68.A N ASP 64.A O no hydrogen 2.875 N/A TRP 69.A N VAL 65.A O no hydrogen 2.887 N/A ASP 70.A N ILE 66.A O no hydrogen 2.947 N/A GLN 71.A N SER 67.A O no hydrogen 3.202 N/A GLN 71.A N LEU 68.A O no hydrogen 3.268 N/A SER 72.A N LEU 68.A O no hydrogen 2.945 N/A SER 72.A OG LEU 68.A O no hydrogen 3.101 N/A LEU 73.A N TRP 69.A O no hydrogen 2.826 N/A GLN 74.A NE2 GLN 87.A OE1 no hydrogen 2.737 N/A CYS 76.A N MET 281.A O no hydrogen 2.825 N/A VAL 77.A N MET 281.A O no hydrogen 3.322 N/A LYS 78.A N ILE 85.A O no hydrogen 2.993 N/A SER 83.A OG THR 80.A O no hydrogen 2.591 N/A ILE 85.A N LYS 78.A O no hydrogen 2.994 N/A GLN 87.A N CYS 76.A O no hydrogen 3.174 N/A LYS 91.A NZ GLU 242.A OE2 no hydrogen 2.734 N/A LYS 91.A NZ ALA 283.A O no hydrogen 3.251 N/A LYS 91.A NZ PRO 284.A O no hydrogen 2.753 N/A ASP 95.A N GLU 21.A OE2 no hydrogen 2.743 N/A ILE 99.A N ILE 135.A O no hydrogen 2.818 N/A HIS 100.A N ALA 12.A O no hydrogen 2.788 N/A HIS 100.A ND1 THR 132.A O no hydrogen 2.841 N/A TYR 101.A N THR 132.A OG1 no hydrogen 3.155 N/A TYR 101.A OH ASP 64.A OD2 no hydrogen 2.861 N/A CYS 102.A N PHE 10.A O no hydrogen 2.841 N/A THR 103.A N GLN 130.A O no hydrogen 3.095 N/A THR 103.A OG1 TYR 107.A O no hydrogen 3.057 N/A TYR 107.A N PRO 104.A O no hydrogen 3.292 N/A VAL 108.A N VAL 336.A O no hydrogen 3.095 N/A ILE 109.A N VAL 129.A O no hydrogen 3.016 N/A LEU 110.A N LYS 334.A O no hydrogen 2.927 N/A LYS 111.A N SER 127.A O no hydrogen 2.886 N/A CYS 112.A N LYS 332.A O no hydrogen 2.798 N/A ASN 113.A N ASN 125.A O no hydrogen 2.508 N/A ASN 113.A ND2 SER 127.A OG no hydrogen 3.048 N/A LYS 115.A NZ GLU 151.A OE1 no hydrogen 2.265 N/A PHE 117.A N ASP 114.A O no hydrogen 3.123 N/A THR 120.A N ASN 118.A OD1 no hydrogen 3.106 N/A GLY 121.A N PHE 50.A O no hydrogen 3.000 N/A CYS 123.A N GLU 48.A O no hydrogen 2.614 N/A CYS 123.A SG ASP 114.A OD2 no hydrogen 3.146 N/A CYS 123.A SG ASN 125.A O no hydrogen 3.531 N/A LYS 124.A N ASP 114.A OD2 no hydrogen 2.890 N/A ASN 125.A N ASP 114.A OD1 no hydrogen 3.111 N/A ASN 125.A ND2 ASN 113.A O no hydrogen 3.573 N/A SER 127.A N LYS 111.A O no hydrogen 3.000 N/A SER 127.A OG GLU 40.A OE2 no hydrogen 2.870 N/A SER 128.A N ILE 41.A O no hydrogen 2.522 N/A VAL 129.A N ILE 109.A O no hydrogen 2.998 N/A THR 132.A N TYR 101.A O no hydrogen 2.858 N/A THR 132.A OG1 HIS 133.A O no hydrogen 3.247 N/A HIS 133.A N TYR 333.A OH no hydrogen 3.279 N/A HIS 133.A ND1 TYR 333.A OH no hydrogen 2.457 N/A HIS 133.A NE2 GLU 329.A OE1 no hydrogen 2.973 N/A ILE 135.A N ILE 99.A O no hydrogen 3.023 N/A VAL 138.A N LYS 136.A O no hydrogen 2.728 N/A SER 140.A OG LEU 143.A O no hydrogen 2.810 N/A THR 141.A N SER 236.A O no hydrogen 3.068 N/A THR 141.A OG1 GLU 231.A O no hydrogen 2.632 N/A THR 141.A OG1 MET 234.A O no hydrogen 3.000 N/A THR 141.A OG1 SER 236.A OG no hydrogen 2.897 N/A GLN 142.A N GLY 318.A O no hydrogen 3.128 N/A GLN 142.A NE2 ILE 232.A O no hydrogen 3.049 N/A LEU 143.A N THR 141.A O no hydrogen 2.467 N/A LEU 144.A N GLY 298.A O no hydrogen 2.850 N/A ASN 146.A N ASN 295.A O no hydrogen 2.887 N/A GLY 147.A N THR 297.A OG1 no hydrogen 3.192 N/A SER 148.A N GLU 329.A OE2 no hydrogen 2.577 N/A SER 148.A OG GLU 329.A OE1 no hydrogen 2.577 N/A SER 148.A OG GLU 329.A OE2 no hydrogen 3.118 N/A ALA 150.A N LEU 172.A O no hydrogen 2.823 N/A ILE 155.A N HIS 171.A O no hydrogen 3.297 N/A ARG 157.A N ILE 169.A O no hydrogen 2.950 N/A ARG 157.A NH1 PHE 117.A O no hydrogen 3.057 N/A ARG 157.A NH2 HIS 171.A ND1 no hydrogen 2.931 N/A ASN 160.A N SER 158.A OG no hydrogen 3.244 N/A ASN 163.A N ASN 160.A O no hydrogen 3.057 N/A ALA 165.A N ASN 163.A OD1 no hydrogen 2.824 N/A LYS 166.A N ASN 163.A O no hydrogen 3.135 N/A LYS 166.A NZ GLU 159.A OE1 no hydrogen 3.369 N/A THR 167.A OG1 ASP 324.A OD2 no hydrogen 3.422 N/A ILE 168.A N LEU 301.A O no hydrogen 3.021 N/A ILE 169.A N ARG 157.A O no hydrogen 2.832 N/A VAL 170.A N ILE 299.A O no hydrogen 2.834 N/A HIS 171.A N ILE 155.A O no hydrogen 2.991 N/A HIS 171.A NE2 SER 148.A O no hydrogen 2.695 N/A LEU 172.A N THR 297.A O no hydrogen 3.145 N/A ASN 173.A ND2 GLU 152.A O no hydrogen 2.650 N/A VAL 176.A N ILE 296.A O no hydrogen 3.406 N/A ILE 178.A N SER 294.A O no hydrogen 2.860 N/A ASN 179.A N GLU 194.A O no hydrogen 3.092 N/A CYS 180.A N CYS 292.A O no hydrogen 3.162 N/A THR 181.A N TYR 192.A O no hydrogen 2.797 N/A THR 181.A OG1 ASN 179.A OD1 no hydrogen 3.490 N/A ARG 182.A N ILE 290.A O no hydrogen 2.663 N/A ARG 182.A NE ARG 182.A O no hydrogen 2.824 N/A ARG 182.A NH1 ILE 188.A O no hydrogen 2.674 N/A ARG 182.A NH2 ILE 286.A O no hydrogen 2.683 N/A ARG 182.A NH2 GLY 288.A O no hydrogen 2.827 N/A ARG 189.A NE GLN 269.A OE1 no hydrogen 2.842 N/A ARG 189.A NH2 GLN 269.A OE1 no hydrogen 2.502 N/A LYS 190.A N ASP 187.A O no hydrogen 3.131 N/A ALA 191.A N CYS 265.A O no hydrogen 2.991 N/A TYR 192.A N THR 181.A O no hydrogen 3.204 N/A CYS 193.A N LEU 263.A O no hydrogen 3.058 N/A GLU 194.A N ASN 179.A O no hydrogen 2.783 N/A ILE 195.A N ILE 261.A O no hydrogen 2.814 N/A GLY 197.A N GLY 259.A O no hydrogen 2.724 N/A THR 198.A OG1 ASN 258.A O no hydrogen 2.761 N/A TRP 200.A N ASN 196.A O no hydrogen 3.062 N/A TRP 200.A NE1 LEU 251.A O no hydrogen 3.168 N/A ASN 201.A N GLY 197.A O no hydrogen 2.916 N/A LYS 202.A N THR 198.A O no hydrogen 3.382 N/A VAL 203.A N LYS 199.A O no hydrogen 3.277 N/A LEU 204.A N TRP 200.A O no hydrogen 2.842 N/A LYS 205.A N ASN 201.A O no hydrogen 3.245 N/A GLN 206.A N LYS 202.A O no hydrogen 3.213 N/A VAL 207.A N VAL 203.A O no hydrogen 2.907 N/A THR 208.A N LEU 204.A O no hydrogen 2.780 N/A THR 208.A OG1 LEU 204.A O no hydrogen 2.724 N/A GLU 209.A N LYS 205.A O no hydrogen 2.834 N/A LYS 210.A N GLN 206.A O no hydrogen 3.043 N/A LYS 210.A NZ GLU 213.A OE1 no hydrogen 3.080 N/A LEU 211.A N VAL 207.A O no hydrogen 3.235 N/A GLU 213.A N LYS 210.A O no hydrogen 3.232 N/A HIS 214.A N LEU 211.A O no hydrogen 3.139 N/A HIS 214.A ND1 LYS 210.A O no hydrogen 2.475 N/A PHE 215.A N LEU 211.A O no hydrogen 3.104 N/A PHE 215.A N LYS 212.A O no hydrogen 3.309 N/A ASN 217.A N LYS 212.A O no hydrogen 2.612 N/A THR 219.A N SER 311.A O no hydrogen 2.939 N/A THR 219.A OG1 SER 311.A O no hydrogen 3.358 N/A ILE 221.A N GLU 313.A O no hydrogen 3.113 N/A GLN 223.A N PHE 315.A O no hydrogen 2.906 N/A GLU 231.A N GLU 231.A OE1 no hydrogen 2.748 N/A ILE 232.A N ASP 229.A O no hydrogen 3.199 N/A THR 233.A N ASP 229.A O no hydrogen 2.982 N/A THR 233.A OG1 ASP 229.A O no hydrogen 3.038 N/A MET 234.A N LEU 230.A O no hydrogen 3.042 N/A HIS 235.A N CYS 246.A O no hydrogen 2.845 N/A HIS 235.A ND1 THR 141.A O no hydrogen 2.896 N/A SER 236.A N THR 141.A OG1 no hydrogen 3.033 N/A SER 236.A OG THR 141.A OG1 no hydrogen 2.897 N/A SER 236.A OG GLU 231.A O no hydrogen 3.072 N/A PHE 237.A N PHE 244.A O no hydrogen 3.120 N/A CYS 239.A N GLU 242.A O no hydrogen 2.623 N/A ARG 240.A NE ASN 291.A O no hydrogen 3.031 N/A ARG 240.A NH2 ASN 291.A O no hydrogen 3.002 N/A GLY 241.A N ASN 238.A OD1 no hydrogen 2.918 N/A GLU 242.A N CYS 239.A O no hydrogen 2.958 N/A PHE 244.A N PHE 237.A O no hydrogen 2.706 N/A TYR 245.A N LYS 266.A O no hydrogen 2.602 N/A TYR 245.A OH GLU 231.A OE2 no hydrogen 2.484 N/A CYS 246.A N HIS 235.A O no hydrogen 3.042 N/A ASN 247.A N PRO 264.A O no hydrogen 2.910 N/A THR 248.A OG1 GLN 142.A OE1 no hydrogen 2.627 N/A THR 249.A N ASN 247.A OD1 no hydrogen 2.630 N/A THR 249.A OG1 ASN 247.A OD1 no hydrogen 2.472 N/A GLN 250.A NE2 THR 262.A O no hydrogen 2.694 N/A LEU 251.A N THR 248.A O no hydrogen 3.016 N/A PHE 252.A N THR 248.A O no hydrogen 2.956 N/A ILE 261.A N ILE 195.A O no hydrogen 2.657 N/A LEU 263.A N CYS 193.A O no hydrogen 2.845 N/A CYS 265.A N ALA 191.A O no hydrogen 2.893 N/A CYS 265.A SG LEU 263.A O no hydrogen 3.540 N/A LYS 266.A N TYR 245.A O no hydrogen 2.539 N/A ILE 267.A N ARG 189.A O no hydrogen 2.664 N/A LYS 268.A N PHE 243.A O no hydrogen 3.212 N/A GLN 269.A NE2 TYR 282.A O no hydrogen 3.052 N/A ILE 271.A N ALA 280.A O no hydrogen 2.693 N/A ASN 272.A N GLU 231.A OE2 no hydrogen 3.068 N/A MET 273.A N GLY 278.A O no hydrogen 2.841 N/A GLN 275.A N GLN 275.A OE1 no hydrogen 2.531 N/A GLY 276.A N MET 273.A O no hydrogen 3.012 N/A ALA 280.A N ILE 271.A O no hydrogen 2.682 N/A MET 281.A N VAL 77.A O no hydrogen 3.099 N/A TYR 282.A N GLN 269.A O no hydrogen 2.799 N/A TYR 282.A OH LEU 73.A O no hydrogen 3.214 N/A ILE 286.A N GLU 242.A OE2 no hydrogen 3.262 N/A ILE 290.A N ARG 182.A O no hydrogen 2.984 N/A ASN 291.A ND2 ASN 179.A OD1 no hydrogen 2.744 N/A ASN 291.A ND2 THR 181.A OG1 no hydrogen 2.722 N/A CYS 292.A N CYS 180.A O no hydrogen 2.916 N/A CYS 292.A SG ASN 291.A O no hydrogen 3.354 N/A SER 294.A N ILE 178.A O no hydrogen 3.024 N/A ASN 295.A N ASN 146.A OD1 no hydrogen 3.162 N/A ILE 296.A N VAL 176.A O no hydrogen 3.039 N/A THR 297.A N LEU 144.A O no hydrogen 2.965 N/A GLY 298.A N LEU 144.A O no hydrogen 3.376 N/A ILE 299.A N VAL 170.A O no hydrogen 2.944 N/A LEU 300.A N GLN 142.A O no hydrogen 2.588 N/A LEU 301.A N ILE 168.A O no hydrogen 3.151 N/A THR 302.A N ARG 316.A O no hydrogen 2.638 N/A THR 302.A OG1 ARG 316.A O no hydrogen 3.292 N/A ARG 303.A NH1 GLU 313.A OE1 no hydrogen 3.036 N/A ASP 304.A N THR 314.A O no hydrogen 2.953 N/A THR 310.A OG1 ASN 312.A O no hydrogen 3.078 N/A GLU 313.A N THR 219.A O no hydrogen 2.753 N/A PHE 315.A N ILE 221.A O no hydrogen 2.711 N/A ARG 316.A N THR 302.A O no hydrogen 3.014 N/A ARG 316.A NE ASP 304.A OD1 no hydrogen 3.306 N/A ARG 316.A NE ASP 304.A OD2 no hydrogen 3.325 N/A ARG 316.A NH1 PRO 224.A O no hydrogen 2.478 N/A ARG 316.A NH2 ASP 304.A OD2 no hydrogen 3.304 N/A GLY 318.A N LEU 300.A O no hydrogen 2.831 N/A LYS 323.A N ASN 321.A OD1 no hydrogen 3.110 N/A LYS 323.A NZ GLU 59.A OE1 no hydrogen 2.474 N/A ASP 324.A N ASN 321.A O no hydrogen 2.806 N/A ASN 325.A N ILE 322.A O no hydrogen 2.922 N/A ASN 325.A ND2 VAL 138.A O no hydrogen 3.477 N/A ASN 325.A ND2 SER 140.A O no hydrogen 3.047 N/A TRP 326.A NE1 GLN 62.A OE1 no hydrogen 2.611 N/A ARG 327.A N LYS 323.A O no hydrogen 3.097 N/A ARG 327.A NE MET 52.A O no hydrogen 3.349 N/A SER 328.A N ASP 324.A O no hydrogen 3.088 N/A SER 328.A OG ASN 325.A O no hydrogen 2.524 N/A GLU 329.A N TRP 326.A O no hydrogen 3.281 N/A LEU 330.A N TRP 326.A O no hydrogen 2.809 N/A TYR 333.A OH HIS 133.A ND1 no hydrogen 2.457 N/A LYS 334.A N LEU 110.A O no hydrogen 3.132 N/A LYS 334.A NZ ASP 4.A OD1 no hydrogen 2.940 N/A LYS 334.A NZ GLU 48.A OE1 no hydrogen 2.503 N/A LYS 334.A NZ ASN 49.A O no hydrogen 3.163 N/A VAL 336.A N VAL 108.A O no hydrogen 3.088 N/A GLN 337.A N LYS 3.A O no hydrogen 2.855 N/A ILE 338.A N GLY 106.A O no hydrogen 3.221 N/A GLU 339.A N VAL 1.A O no hydrogen 2.713 N/A