Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4to8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PRO 1.A N ILE 77.A O no hydrogen 2.834 N/A VAL 3.A N VAL 79.A O no hydrogen 2.832 N/A MET 5.A N SER 132.A OG no hydrogen 2.941 N/A LYS 6.A N SER 4.A OG no hydrogen 3.102 N/A LEU 9.A N MET 5.A O no hydrogen 2.905 N/A ILE 10.A N LYS 6.A O no hydrogen 3.184 N/A ASP 11.A N GLU 7.A O no hydrogen 2.949 N/A ALA 12.A N MET 8.A O no hydrogen 3.176 N/A LYS 13.A N LEU 9.A O no hydrogen 2.897 N/A GLU 14.A N ILE 10.A O no hydrogen 2.969 N/A ASN 15.A N ASP 11.A O no hydrogen 3.047 N/A TYR 17.A N ALA 12.A O no hydrogen 3.068 N/A TYR 17.A OH ASP 11.A OD2.B no hydrogen 2.416 N/A ALA 18.A N PHE 271.A O no hydrogen 2.875 N/A VAL 19.A N ALA 220.A O no hydrogen 2.810 N/A GLN 21.A N ILE 222.A O no hydrogen 2.900 N/A GLN 21.A NE2 ASN 23.A OD1 no hydrogen 2.873 N/A GLN 21.A NE2 ASP 84.A OD2 no hydrogen 3.102 N/A TYR 22.A N ILE 45.A O no hydrogen 2.970 N/A ASN 23.A N VAL 224.A O no hydrogen 3.101 N/A ASN 23.A ND2 ASP 84.A OD2 no hydrogen 3.311 N/A ILE 24.A N GLY 47.A O no hydrogen 2.873 N/A GLU 28.A N GLU 28.A OE1 no hydrogen 2.745 N/A PHE 29.A N ASN 26.A OD1 no hydrogen 3.100 N/A THR 30.A N ASN 26.A O no hydrogen 3.211 N/A THR 30.A OG1 ASN 26.A O no hydrogen 2.894 N/A GLN 31.A N LEU 27.A O no hydrogen 2.911 N/A ALA 32.A N GLU 28.A O no hydrogen 3.065 N/A ILE 33.A N PHE 29.A O no hydrogen 3.090 N/A LEU 34.A N THR 30.A O no hydrogen 3.082 N/A GLU 35.A N GLN 31.A O no hydrogen 2.930 N/A ALA 36.A N ALA 32.A O no hydrogen 2.945 N/A SER 37.A N ILE 33.A O no hydrogen 3.150 N/A SER 37.A OG ILE 33.A O no hydrogen 2.941 N/A GLN 38.A N LEU 34.A O no hydrogen 2.976 N/A GLN 38.A NE2 THR 76.A OG1 no hydrogen 2.904 N/A GLU 39.A N GLU 35.A O no hydrogen 2.948 N/A GLU 40.A N ALA 36.A O no hydrogen 3.039 N/A GLU 40.A N SER 37.A O no hydrogen 3.147 N/A ASN 41.A N GLN 38.A O no hydrogen 3.047 N/A ASN 41.A ND2 ASN 275.A OD1 no hydrogen 2.838 N/A ALA 42.A N SER 37.A O no hydrogen 2.859 N/A VAL 44.A N PRO 78.A O no hydrogen 3.070 N/A ILE 45.A N GLY 20.A O no hydrogen 3.341 N/A LEU 46.A N ALA 80.A O no hydrogen 2.810 N/A GLY 47.A N TYR 22.A O no hydrogen 2.999 N/A VAL 48.A N HIS 82.A O no hydrogen 2.832 N/A ALA 52.A N SER 49.A OG no hydrogen 3.041 N/A ALA 53.A N SER 49.A O no hydrogen 2.939 N/A ARG 54.A N GLU 50.A O no hydrogen 3.085 N/A TYR 55.A N GLY 51.A O no hydrogen 3.029 N/A MET 56.A N ALA 52.A O no hydrogen 2.890 N/A SER 57.A N ARG 54.A O no hydrogen 3.085 N/A ILE 62.A N GLY 58.A O no hydrogen 3.183 N/A VAL 63.A N PHE 59.A O no hydrogen 3.015 N/A LYS 64.A N TYR 60.A O no hydrogen 2.983 N/A MET 65.A N.A THR 61.A O no hydrogen 2.975 N/A MET 65.A N.B THR 61.A O no hydrogen 2.964 N/A VAL 66.A N ILE 62.A O no hydrogen 2.992 N/A GLU 67.A N VAL 63.A O no hydrogen 2.905 N/A GLY 68.A N LYS 64.A O no hydrogen 2.883 N/A LEU 69.A N MET 65.A O.A no hydrogen 2.921 N/A LEU 69.A N MET 65.A O.B no hydrogen 2.946 N/A MET 70.A N VAL 66.A O no hydrogen 2.766 N/A HIS 71.A N GLU 67.A O no hydrogen 3.260 N/A ASP 72.A N GLY 68.A O no hydrogen 2.868 N/A LEU 73.A N LEU 69.A O no hydrogen 2.776 N/A ASN 74.A N HIS 71.A O no hydrogen 3.152 N/A ILE 75.A N MET 70.A O no hydrogen 3.027 N/A THR 76.A N GLN 38.A OE1 no hydrogen 2.702 N/A ILE 77.A N GLN 38.A OE1 no hydrogen 3.209 N/A VAL 79.A N PRO 1.A O no hydrogen 2.826 N/A ALA 80.A N VAL 44.A O no hydrogen 3.048 N/A ILE 81.A N THR 101.A OG1 no hydrogen 2.965 N/A HIS 82.A N LEU 46.A O no hydrogen 2.788 N/A HIS 82.A ND1 SER 102.A OG no hydrogen 2.961 N/A LEU 83.A N SER 102.A O no hydrogen 2.960 N/A ASP 84.A N VAL 48.A O no hydrogen 2.730 N/A HIS 85.A ND1 ASP 106.A OD2 no hydrogen 2.794 N/A GLY 86.A N MET 104.A O no hydrogen 2.762 N/A SER 87.A N GLU 50.A OE2 no hydrogen 2.723 N/A SER 87.A OG GLU 50.A OE1 no hydrogen 2.748 N/A SER 87.A OG GLU 50.A OE2 no hydrogen 3.038 N/A LYS 91.A N SER 88.A OG no hydrogen 3.087 N/A LYS 91.A NZ GLU 94.A OE1 no hydrogen 3.190 N/A CYS 92.A N SER 88.A O no hydrogen 3.090 N/A CYS 92.A SG SER 88.A O no hydrogen 3.410 N/A LYS 93.A N PHE 89.A O no hydrogen 2.815 N/A GLU 94.A N GLU 90.A O no hydrogen 2.937 N/A ALA 95.A N LYS 91.A O no hydrogen 3.095 N/A ILE 96.A N CYS 92.A O no hydrogen 3.057 N/A ASP 97.A N LYS 93.A O no hydrogen 2.806 N/A ALA 98.A N GLU 94.A O no hydrogen 3.089 N/A ALA 98.A N ALA 95.A O no hydrogen 3.202 N/A GLY 99.A N ILE 96.A O no hydrogen 3.017 N/A PHE 100.A N ALA 95.A O no hydrogen 2.983 N/A THR 101.A N ILE 81.A O no hydrogen 3.050 N/A THR 101.A OG1 VAL 3.A O no hydrogen 2.769 N/A THR 101.A OG1 ILE 81.A O no hydrogen 3.513 N/A SER 102.A OG HIS 82.A ND1 no hydrogen 2.961 N/A SER 102.A OG SER 132.A O no hydrogen 3.419 N/A SER 102.A OG SER 132.A OG no hydrogen 2.633 N/A VAL 103.A N SER 132.A O no hydrogen 2.955 N/A MET 104.A N LEU 83.A O no hydrogen 2.788 N/A ILE 105.A N GLU 134.A O no hydrogen 2.919 N/A ASP 106.A N GLY 86.A O no hydrogen 2.738 N/A SER 108.A N ASP 106.A OD1 no hydrogen 3.058 N/A SER 108.A OG ASP 106.A OD1 no hydrogen 2.821 N/A SER 110.A N ALA 107.A O no hydrogen 3.066 N/A GLU 114.A N PRO 111.A O no hydrogen 2.844 N/A ASN 115.A N PRO 111.A O no hydrogen 2.978 N/A ASN 115.A ND2 GLU 136.A O no hydrogen 3.078 N/A VAL 116.A N PHE 112.A O no hydrogen 2.970 N/A ALA 117.A N GLU 113.A O no hydrogen 3.090 N/A THR 118.A N GLU 114.A O no hydrogen 2.862 N/A THR 118.A OG1 GLU 114.A O no hydrogen 3.221 N/A THR 119.A N ASN 115.A O no hydrogen 2.935 N/A THR 119.A OG1 ASN 115.A O no hydrogen 2.791 N/A THR 119.A OG1 ASN 115.A OD1 no hydrogen 3.066 N/A LYS 120.A N VAL 116.A O no hydrogen 2.896 N/A LYS 121.A N ALA 117.A O no hydrogen 3.113 N/A VAL 122.A N THR 118.A O no hydrogen 3.016 N/A VAL 123.A N THR 119.A O no hydrogen 2.897 N/A GLU 124.A N LYS 120.A O no hydrogen 3.068 N/A TYR 125.A N LYS 121.A O no hydrogen 3.297 N/A TYR 125.A OH ASP 97.A OD1 no hydrogen 2.562 N/A ALA 126.A N VAL 122.A O no hydrogen 2.798 N/A HIS 127.A N VAL 123.A O no hydrogen 2.810 N/A HIS 127.A NE2 ASP 168.A OD2 no hydrogen 2.830 N/A LYS 129.A N ALA 126.A O no hydrogen 2.913 N/A GLY 130.A N HIS 127.A O no hydrogen 3.470 N/A VAL 131.A N ALA 126.A O no hydrogen 2.794 N/A SER 132.A N THR 101.A O no hydrogen 3.281 N/A SER 132.A OG SER 102.A OG no hydrogen 2.633 N/A VAL 133.A N ASP 168.A OD2 no hydrogen 2.755 N/A GLU 134.A N VAL 103.A O no hydrogen 2.851 N/A ALA 135.A N ALA 169.A O no hydrogen 3.281 N/A LEU 137.A N ALA 171.A O no hydrogen 3.047 N/A THR 139.A N ILE 151.A O no hydrogen 2.823 N/A GLY 141.A N SER 176.A O no hydrogen 3.033 N/A GLY 142.A N ASP 148.A O no hydrogen 2.830 N/A ASP 144.A N ASP 143.A OD1 no hydrogen 2.807 N/A ASP 148.A N VAL 145.A O no hydrogen 2.937 N/A GLY 149.A N VAL 146.A O no hydrogen 3.011 N/A ILE 150.A N ALA 147.A O no hydrogen 3.042 N/A ILE 151.A N THR 139.A O no hydrogen 3.236 N/A ALA 153.A N ALA 173.A O no hydrogen 2.857 N/A GLU 157.A N ASP 154.A OD1 no hydrogen 2.863 N/A CYS 158.A N ASP 154.A O no hydrogen 2.676 N/A CYS 158.A SG ASP 154.A O no hydrogen 3.381 N/A GLN 159.A N PRO 155.A O no hydrogen 2.976 N/A GLN 159.A NE2 GLU 163.A OE2 no hydrogen 2.683 N/A GLN 159.A NE2 SER 193.A O no hydrogen 3.326 N/A GLU 160.A N LYS 156.A O no hydrogen 2.931 N/A LEU 161.A N GLU 157.A O no hydrogen 2.831 N/A VAL 162.A N CYS 158.A O no hydrogen 3.116 N/A GLU 163.A N GLN 159.A O no hydrogen 3.105 N/A LYS 164.A N GLU 160.A O no hydrogen 2.925 N/A LYS 164.A NZ GLU 160.A OE1 no hydrogen 2.500 N/A THR 165.A N LEU 161.A O no hydrogen 2.982 N/A THR 165.A OG1 LEU 161.A O no hydrogen 2.644 N/A GLY 166.A N VAL 162.A O no hydrogen 3.052 N/A ILE 167.A N THR 165.A OG1 no hydrogen 3.387 N/A ASP 168.A N VAL 133.A O no hydrogen 2.963 N/A ALA 169.A N VAL 133.A O no hydrogen 3.200 N/A LEU 170.A N PRO 197.A O no hydrogen 3.201 N/A ALA 171.A N ALA 135.A O no hydrogen 2.843 N/A ALA 173.A N LEU 137.A O no hydrogen 2.948 N/A SER 176.A OG HIS 201.A O no hydrogen 2.823 N/A HIS 178.A N GLY 141.A O no hydrogen 2.621 N/A GLY 183.A N LEU 174.A O no hydrogen 2.894 N/A GLU 186.A N GLU 186.A OE1 no hydrogen 2.635 N/A MET 187.A N GLY 183.A O no hydrogen 2.828 N/A GLU 188.A N PHE 184.A O no hydrogen 2.975 N/A GLU 189.A N LYS 185.A O no hydrogen 3.072 N/A ILE 190.A N GLU 186.A O no hydrogen 3.046 N/A GLY 191.A N MET 187.A O no hydrogen 2.995 N/A LEU 192.A N GLU 188.A O no hydrogen 2.977 N/A SER 193.A N GLU 189.A O no hydrogen 2.819 N/A SER 193.A OG GLN 159.A OE1 no hydrogen 2.699 N/A SER 193.A OG GLU 189.A O no hydrogen 3.328 N/A SER 193.A OG ILE 190.A O no hydrogen 3.535 N/A THR 194.A N ILE 190.A O no hydrogen 2.934 N/A THR 194.A OG1 ILE 190.A O no hydrogen 2.676 N/A GLY 195.A N GLY 191.A O no hydrogen 2.872 N/A LEU 196.A N THR 194.A OG1 no hydrogen 3.340 N/A LEU 198.A N GLY 218.A O no hydrogen 2.919 N/A VAL 199.A N LEU 170.A O no hydrogen 2.714 N/A LEU 200.A N LYS 221.A O no hydrogen 2.845 N/A HIS 201.A NE2 GLU 134.A OE2 no hydrogen 2.766 N/A THR 204.A OG1 THR 226.A OG1 no hydrogen 2.977 N/A ILE 206.A N GLY 203.A O no hydrogen 2.929 N/A THR 208.A OG1 GLU 270.A OE1 no hydrogen 3.235 N/A ILE 211.A N PRO 207.A O no hydrogen 3.120 N/A GLN 212.A N THR 208.A O no hydrogen 2.719 N/A GLN 212.A NE2 GLU 270.A O no hydrogen 3.381 N/A LYS 213.A N LYS 209.A O no hydrogen 2.937 N/A ALA 214.A N ASP 210.A O no hydrogen 2.880 N/A ILE 215.A N ILE 211.A O no hydrogen 3.361 N/A PHE 217.A N ALA 214.A O no hydrogen 3.168 N/A GLY 218.A N ILE 215.A O no hydrogen 3.021 N/A THR 219.A N ALA 214.A O no hydrogen 3.275 N/A THR 219.A OG1 ALA 214.A O no hydrogen 3.423 N/A ALA 220.A N LEU 198.A O no hydrogen 2.798 N/A LYS 221.A N LEU 198.A O no hydrogen 3.267 N/A LYS 221.A NZ GLN 21.A OE1 no hydrogen 2.767 N/A LYS 221.A NZ GLU 134.A OE1 no hydrogen 2.853 N/A LYS 221.A NZ ASN 223.A OD1 no hydrogen 2.872 N/A ILE 222.A N VAL 19.A O no hydrogen 3.281 N/A ASN 223.A N LEU 200.A O no hydrogen 3.192 N/A VAL 224.A N GLN 21.A O no hydrogen 2.711 N/A THR 226.A OG1 THR 204.A OG1 no hydrogen 2.977 N/A ASN 228.A N ASN 225.A O no hydrogen 2.955 N/A GLN 229.A N ASN 225.A O no hydrogen 3.195 N/A GLN 229.A NE2 ASN 25.A OD1 no hydrogen 3.271 N/A ILE 230.A N THR 226.A O no hydrogen 2.814 N/A ALA 231.A N GLU 227.A O no hydrogen 3.168 N/A SER 232.A N ASN 228.A O no hydrogen 2.986 N/A SER 232.A OG ASN 228.A O no hydrogen 2.748 N/A SER 232.A OG GLN 229.A O no hydrogen 3.095 N/A ALA 233.A N GLN 229.A O no hydrogen 2.946 N/A LYS 234.A N ILE 230.A O no hydrogen 3.017 N/A LYS 234.A NZ ASP 238.A OD2 no hydrogen 2.884 N/A ALA 235.A N ALA 231.A O no hydrogen 3.170 N/A VAL 236.A N SER 232.A O no hydrogen 3.044 N/A ARG 237.A N ALA 233.A O no hydrogen 2.996 N/A ASP 238.A N LYS 234.A O no hydrogen 3.010 N/A VAL 239.A N ALA 235.A O no hydrogen 3.107 N/A LEU 240.A N VAL 236.A O no hydrogen 2.934 N/A ASN 241.A N ARG 237.A O no hydrogen 2.746 N/A ASN 242.A N ASP 238.A O no hydrogen 3.204 N/A ASP 243.A N VAL 239.A O no hydrogen 3.094 N/A GLU 245.A N ASP 243.A OD1 no hydrogen 2.819 N/A ARG 250.A N ASP 248.A OD1 no hydrogen 2.963 N/A LYS 251.A N ASP 248.A O no hydrogen 2.946 N/A TYR 252.A N PRO 249.A O no hydrogen 3.391 N/A LEU 253.A N PRO 249.A O no hydrogen 2.896 N/A GLY 254.A N ARG 250.A O no hydrogen 2.912 N/A ALA 256.A N TYR 252.A O no hydrogen 3.180 N/A ARG 257.A N LEU 253.A O no hydrogen 2.882 N/A ARG 257.A NH1 GLN 31.A OE1 no hydrogen 2.813 N/A GLU 258.A N GLY 254.A O no hydrogen 2.976 N/A ALA 259.A N PRO 255.A O no hydrogen 2.874 N/A ILE 260.A N ALA 256.A O no hydrogen 2.980 N/A LYS 261.A N ARG 257.A O no hydrogen 2.935 N/A LYS 261.A NZ GLU 35.A OE1 no hydrogen 2.740 N/A LYS 261.A NZ GLU 39.A OE1 no hydrogen 3.306 N/A LYS 261.A NZ GLU 39.A OE2 no hydrogen 2.748 N/A GLU 262.A N GLU 258.A O no hydrogen 3.003 N/A THR 263.A N ALA 259.A O no hydrogen 3.072 N/A THR 263.A OG1 ALA 259.A O no hydrogen 2.887 N/A VAL 264.A N ILE 260.A O no hydrogen 2.840 N/A LYS 265.A N LYS 261.A O no hydrogen 3.058 N/A LYS 265.A NZ GLU 39.A OE1 no hydrogen 2.708 N/A GLY 266.A N GLU 262.A O no hydrogen 3.157 N/A LYS 267.A N THR 263.A O no hydrogen 3.089 N/A LYS 267.A NZ GLU 227.A OE1 no hydrogen 3.513 N/A LYS 267.A NZ GLU 227.A OE2 no hydrogen 2.855 N/A LYS 267.A NZ GLU 270.A OE2 no hydrogen 3.164 N/A ILE 268.A N VAL 264.A O no hydrogen 2.791 N/A LYS 269.A N LYS 265.A O no hydrogen 2.917 N/A LYS 269.A NZ GLU 40.A OE2 no hydrogen 2.770 N/A GLU 270.A N GLY 266.A O no hydrogen 3.037 N/A PHE 271.A N LYS 267.A O no hydrogen 2.829 N/A GLY 272.A N ILE 268.A O no hydrogen 3.034 N/A THR 273.A N ILE 268.A O no hydrogen 3.173 N/A THR 273.A OG1 ALA 18.A O no hydrogen 2.677 N/A SER 274.A OG GLU 40.A OE2 no hydrogen 2.638 N/A ASN 275.A N GLU 40.A O no hydrogen 2.920 N/A ARG 276.A NE GLY 272.A O no hydrogen 2.858 N/A ARG 276.A NH2 GLY 272.A O no hydrogen 3.462 N/A ALA 277.A N ASN 41.A O no hydrogen 2.962 N/A